Leaf Huang - Publications

Affiliations: 
1976-1991 University of Tennessee, Knoxville, Knoxville, TN, United States 
 1991-2005 University of Pittsburgh, Pittsburgh, PA, United States 
 2005-2012 Pharmaceutical Sciences University of North Carolina, Chapel Hill, Chapel Hill, NC 
Website:
https://pharmacy.unc.edu/news/directory/leafh/

303 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang M, Rousseau B, Qiu K, Huang G, Zhang Y, Su H, Le Bihan-Benjamin C, Khati I, Artz O, Foote MB, Cheng YY, Lee KH, Miao MZ, Sun Y, Bousquet PJ, ... ... Huang L, et al. Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses. Nature Biotechnology. PMID 37749267 DOI: 10.1038/s41587-023-01957-8  0.762
2022 Liu X, Zhou J, Wu H, Chen S, Zhang L, Tang W, Duan L, Wang Y, McCabe E, Hu M, Yu Z, Liu H, Choi CHJ, Sung JJ, Huang L, et al. Fibrotic immune microenvironment remodelling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36146933 DOI: 10.1016/j.ymthe.2022.09.012  0.671
2022 Hu M, Huang L. Strategies targeting tumor immune and stromal microenvironment and their clinical relevance. Advanced Drug Delivery Reviews. 183: 114137. PMID 35143893 DOI: 10.1016/j.addr.2022.114137  0.689
2022 Yu Z, Guo J, Liu Y, Wang M, Liu Z, Gao Y, Huang L. Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma. Journal of Nanobiotechnology. 20: 9. PMID 34983554 DOI: 10.1186/s12951-021-01205-8  0.542
2021 Sendi H, Yazdimamaghani M, Hu M, Sultanpuram N, Wang J, Moody AS, McCabe E, Zhang J, Graboski A, Li L, Rojas JD, Dayton PA, Huang L, Wang AZ. Nanoparticle delivery of miR-122 inhibits colorectal cancer liver metastasis. Cancer Research. PMID 34753773 DOI: 10.1158/0008-5472.CAN-21-2269  0.657
2021 Xi Y, Li Y, Xu P, Li S, Liu Z, Tung HC, Cai X, Wang J, Huang H, Wang M, Xu M, Ren S, Li S, Zhang M, Lee YJ, ... Huang L, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Science Advances. 7: eabg9241. PMID 34516906 DOI: 10.1126/sciadv.abg9241  0.573
2021 Qiu N, Liu Y, Liu Q, Chen Y, Shen L, Hu M, Zhou X, Shen Y, Gao J, Huang L. Corrigendum to "Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy" [Biomaterials 269 (2021) 120604]. Biomaterials. 277: 121121. PMID 34507130 DOI: 10.1016/j.biomaterials.2021.121121  0.63
2021 Musetti SN, Huang L. Tinagl1 Gene Therapy Suppresses Growth and Remodels the Microenvironment of Triple Negative Breast Cancer. Molecular Pharmaceutics. 18: 2032-2038. PMID 33877834 DOI: 10.1021/acs.molpharmaceut.1c00008  0.787
2021 Zhou X, Liu Y, Hu M, Wang M, Liu X, Huang L. Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy. Science Advances. 7. PMID 33597232 DOI: 10.1126/sciadv.abb6596  0.78
2021 Liu Y, Tiruthani K, Wang M, Zhou X, Qiu N, Xiong Y, Pecot CV, Liu R, Huang L. Tumor-targeted gene therapy with lipid nanoparticles inhibits tumor-associated adipocytes and remodels the immunosuppressive tumor microenvironment in triple-negative breast cancer. Nanoscale Horizons. PMID 33587080 DOI: 10.1039/d0nh00588f  0.624
2021 Hu M, Wang Y, Liu Z, Yu Z, Guan K, Liu M, Wang M, Tan J, Huang L. Hepatic macrophages act as a central hub for relaxin-mediated alleviation of liver fibrosis. Nature Nanotechnology. PMID 33495618 DOI: 10.1038/s41565-020-00836-6  0.744
2020 Qiu N, Liu Y, Liu Q, Chen Y, Shen L, Hu M, Zhou X, Shen Y, Gao J, Huang L. Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy. Biomaterials. 269: 120604. PMID 33383300 DOI: 10.1016/j.biomaterials.2020.120604  0.673
2020 Qiu N, Liu Y, Liu Q, Chen Y, Shen L, Hu M, Zhou X, Shen Y, Gao J, Huang L. Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy. Biomaterials. 269: 120604. PMID 33383300 DOI: 10.1016/j.biomaterials.2020.120604  0.673
2020 Chen R, Huang L, Hu K. Natural products remodel cancer-associated fibroblasts in desmoplastic tumors. Acta Pharmaceutica Sinica. B. 10: 2140-2155. PMID 33304782 DOI: 10.1016/J.Apsb.2020.04.005  0.388
2020 Harrison EB, Porrello A, Bowman BM, Belanger AR, Yacovone G, Azam SH, Windham IA, Ghosh SK, Wang M, McKenzie N, Waugh TA, Van Swearingen AED, Cohen SM, Allen DG, Goodwin TJ, ... ... Huang L, et al. A circle RNA regulatory axis promotes lung squamous metastasis via CDR1-mediated regulation of Golgi trafficking. Cancer Research. PMID 32978168 DOI: 10.1158/0008-5472.CAN-20-1162  0.513
2020 Yang Y, Guo J, Huang L. Tackling TAMs for Cancer Immunotherapy: It's Nano Time. Trends in Pharmacological Sciences. 41: 701-714. PMID 32946772 DOI: 10.1016/j.tips.2020.08.003  0.308
2020 Das M, Zhou X, Liu Y, Das A, Vincent BG, Li J, Liu R, Huang L. Tumor neoantigen heterogeneity impacts bystander immune inhibition of pancreatic cancer growth. Translational Oncology. 13: 100856. PMID 32862105 DOI: 10.1016/J.Tranon.2020.100856  0.411
2020 Das M, Li J, Bao M, Huang L. Nano-delivery of Gemcitabine Derivative as a Therapeutic Strategy in a Desmoplastic KRAS Mutant Pancreatic Cancer. The Aaps Journal. 22: 88. PMID 32572645 DOI: 10.1208/S12248-020-00467-8  0.412
2020 Zhang J, Li X, Huang L. Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment. Advanced Drug Delivery Reviews. PMID 32473991 DOI: 10.1016/J.Addr.2020.05.006  0.411
2020 Guo J, Huang L. Membrane-core nanoparticles for cancer nanomedicine. Advanced Drug Delivery Reviews. PMID 32450105 DOI: 10.1016/J.Addr.2020.05.005  0.361
2020 Liu Y, Qiu N, Shen L, Liu Q, Zhang J, Cheng YY, Lee KH, Huang L. Nanocarrier-mediated immunogenic chemotherapy for triple negative breast cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32360890 DOI: 10.1016/J.Jconrel.2020.04.040  0.712
2020 Guo J, Yu Z, Das M, Huang L. Nano Codelivery of Oxaliplatin and Folinic Acid Achieves Synergistic Chemo-Immunotherapy with 5-Fluorouracil for Colorectal Cancer and Liver Metastasis. Acs Nano. PMID 32283007 DOI: 10.1021/Acsnano.0C01676  0.391
2020 Yu Z, Guo J, Hu M, Gao Y, Huang L. Icaritin Exacerbates Mitophagy and Synergizes with Doxorubicin to Induce Immunogenic Cell Death in Hepatocellular Carcinoma. Acs Nano. PMID 32188241 DOI: 10.1021/Acsnano.0C00708  0.646
2020 Yu Z, Guo J, Hu M, Gao Y, Huang L. Icaritin Exacerbates Mitophagy and Synergizes with Doxorubicin to Induce Immunogenic Cell Death in Hepatocellular Carcinoma. Acs Nano. PMID 32188241 DOI: 10.1021/Acsnano.0C00708  0.646
2020 Zhu H, Liu Q, Miao L, Musetti S, Huo M, Huang L. Remodeling the fibrotic tumor microenvironment of desmoplastic melanoma to facilitate vaccine immunotherapy. Nanoscale. PMID 31989142 DOI: 10.1039/C9Nr09610H  0.787
2020 Zhu H, Liu Q, Miao L, Musetti S, Huo M, Huang L. Remodeling the fibrotic tumor microenvironment of desmoplastic melanoma to facilitate vaccine immunotherapy. Nanoscale. PMID 31989142 DOI: 10.1039/C9Nr09610H  0.787
2020 Xu H, Hu M, Liu M, An S, Guan K, Wang M, Li L, Zhang J, Li J, Huang L. Nano-puerarin regulates tumor microenvironment and facilitates chemo- and immunotherapy in murine triple negative breast cancer model. Biomaterials. 235: 119769. PMID 31986348 DOI: 10.1016/J.Biomaterials.2020.119769  0.776
2020 Xu H, Hu M, Liu M, An S, Guan K, Wang M, Li L, Zhang J, Li J, Huang L. Nano-puerarin regulates tumor microenvironment and facilitates chemo- and immunotherapy in murine triple negative breast cancer model. Biomaterials. 235: 119769. PMID 31986348 DOI: 10.1016/J.Biomaterials.2020.119769  0.776
2019 Hu M, Zhou X, Wang Y, Guan K, Huang L. Relaxin-FOLFOX-IL-12 triple combination therapy engages memory response and achieves long-term survival in colorectal cancer liver metastasis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31899270 DOI: 10.1016/J.Jconrel.2019.12.053  0.683
2019 Gusti-Ngurah-Putu EP, Huang L, Hsu YC. Effective Combined Photodynamic Therapy with Lipid Platinum Chloride Nanoparticles Therapies of Oral Squamous Carcinoma Tumor Inhibition. Journal of Clinical Medicine. 8. PMID 31810241 DOI: 10.3390/Jcm8122112  0.406
2019 Zhang J, Shen L, Li X, Song W, Liu Y, Huang L. Nanoformulated Codelivery of Quercetin and Alantolactone Promotes an Antitumor Response through Synergistic Immunogenic Cell Death for Microsatellite-Stable Colorectal Cancer. Acs Nano. PMID 31664821 DOI: 10.1021/Acsnano.9B02875  0.376
2019 Hu M, Wang Y, Xu L, An S, Tang Y, Zhou X, Li J, Liu R, Huang L. Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy. Nature Communications. 10: 2993. PMID 31278269 DOI: 10.1038/S41467-019-10893-8  0.692
2019 Wang M, Zhai Y, Ye H, Lv Q, Sun B, Luo C, Jiang Q, Zhang H, Xu Y, Jing Y, Huang L, Sun J, He Z. High Co-loading Capacity and Stimuli-Responsive Release Based on Cascade Reaction of Self-Destructive Polymer for Improved Chemo-Photodynamic Therapy. Acs Nano. PMID 31188559 DOI: 10.1021/acsnano.9b02096  0.575
2019 Qi C, Musetti S, Fu LH, Zhu YJ, Huang L. Biomolecule-assisted green synthesis of nanostructured calcium phosphates and their biomedical applications. Chemical Society Reviews. PMID 31080987 DOI: 10.1039/c8cs00489g  0.749
2019 An S, Tiruthani K, Wang Y, Xu L, Hu M, Li J, Song W, Jiang H, Sun J, Liu R, Huang L. Locally Trapping the C-C Chemokine Receptor Type 7 by Gene Delivery Nanoparticle Inhibits Lymphatic Metastasis Prior to Tumor Resection. Small (Weinheim An Der Bergstrasse, Germany). e1805182. PMID 30690891 DOI: 10.1002/Smll.201805182  0.703
2019 Chen Y, Song W, Shen L, Qiu N, Hu M, Liu Y, Liu Q, Huang L. Vasodilator Hydralazine Promotes Nanoparticle Penetration in Advanced Desmoplastic Tumor. Acs Nano. PMID 30642161 DOI: 10.1021/acsnano.8b07830  0.698
2018 Das M, Musetti S, Huang L. RNA Interference-Based Cancer Drugs: The Roadblocks, and the "Delivery" of the Promise. Nucleic Acid Therapeutics. PMID 30562145 DOI: 10.1089/nat.2018.0762  0.761
2018 Das M, Shen L, Liu Q, Goodwin TJ, Huang L. Nanoparticle Delivery of RIG-I Agonist Enables Effective and Safe Adjuvant Therapy in Pancreatic Cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30545600 DOI: 10.1016/j.ymthe.2018.11.012  0.311
2018 Sun H, Yang W, Tian Y, Zeng X, Zhou J, Mok MTS, Tang W, Feng Y, Xu L, Chan AWH, Tong JH, Cheung YS, Lai PBS, Wang HKS, Tsang SW, ... ... Huang L, et al. An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma. Nature Communications. 9: 5214. PMID 30523261 DOI: 10.1038/S41467-018-07402-8  0.629
2018 Musetti S, Huang L. Nanoparticle-Mediated Remodeling of the Tumor Microenvironment to Enhance Immunotherapy. Acs Nano. PMID 30508378 DOI: 10.1021/acsnano.8b05893  0.78
2018 Song W, Tiruthani K, Wang Y, Shen L, Hu M, Dorosheva O, Qiu K, Kinghorn KA, Liu R, Huang L. Trapping of Lipopolysaccharide to Promote Immunotherapy against Colorectal Cancer and Attenuate Liver Metastasis. Advanced Materials (Deerfield Beach, Fla.). e1805007. PMID 30387230 DOI: 10.1002/adma.201805007  0.674
2017 Liu L, Wang Y, Miao L, Liu Q, Musetti S, Li J, Huang L. Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29258739 DOI: 10.1016/j.ymthe.2017.10.020  0.768
2017 Liu Q, Zhu H, Liu Y, Musetti S, Huang L. BRAF peptide vaccine facilitates therapy of murine BRAF-mutant melanoma. Cancer Immunology, Immunotherapy : Cii. PMID 29094184 DOI: 10.1007/s00262-017-2079-7  0.774
2017 Song W, Musetti SN, Huang L. Nanomaterials for cancer immunotherapy. Biomaterials. 148: 16-30. PMID 28961532 DOI: 10.1016/j.biomaterials.2017.09.017  0.766
2017 Goodwin TJ, Shen L, Hu M, Li J, Feng R, Dorosheva O, Liu R, Huang L. Liver specific gene immunotherapies resolve immune suppressive ectopic lymphoid structures of liver metastases and prolong survival. Biomaterials. 141: 260-271. PMID 28700955 DOI: 10.1016/j.biomaterials.2017.07.007  0.684
2017 Miao L, Guo S, Lin CM, Liu Q, Huang L. Nanoformulations for Combination or Cascade Anticancer Therapy. Advanced Drug Delivery Reviews. PMID 28624477 DOI: 10.1016/J.Addr.2017.06.003  0.649
2017 Shi K, Zhao Y, Miao L, Satterlee A, Haynes M, Luo C, Musetti S, Huang L. Dual Functional LipoMET Mediates Envelope-type Nanoparticles to Combinational Oncogene Silencing and Tumor Growth Inhibition. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28274796 DOI: 10.1016/j.ymthe.2017.02.008  0.785
2016 Miao L, Liu Q, Lin CM, Luo C, Wang Y, Liu L, Yin W, Hu S, Kim WY, Huang L. Targeting Tumor-associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors. Cancer Research. PMID 27864344 DOI: 10.1158/0008-5472.CAN-16-0866  0.309
2016 Goodwin TJ, Zhou Y, Musetti SN, Liu R, Huang L. Local and transient gene expression primes the liver to resist cancer metastasis. Science Translational Medicine. 8: 364ra153. PMID 27831902 DOI: 10.1126/scitranslmed.aag2306  0.771
2016 Luo C, Sun J, Liu D, Sun B, Miao L, Musetti S, Li J, Han X, Du Y, Li L, Huang L, He Z. Self-Assembled Redox Dual-Responsive Prodrug-Nanosystem Formed by Single Thioether-Bridged Paclitaxel-Fatty Acid Conjugate for Cancer Chemotherapy. Nano Letters. PMID 27490088 DOI: 10.1021/acs.nanolett.6b01632  0.765
2016 Wang B, Liu Y, Huang L, Chen J, Li JJ, Wang R, Kim E, Chen Y, Justicia C, Sakata K, Chen H, Planas A, Ostrom RS, Li W, Yang G, et al. A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism. Molecular Psychiatry. PMID 27457810 DOI: 10.1038/Mp.2016.104  0.418
2016 Huang LB, Tsai YF, Liu CY, Chen YJ. Influencing and protective factors of suicidal ideation among older adults. International Journal of Mental Health Nursing. PMID 27452945 DOI: 10.1111/inm.12247  0.374
2016 Chen CW, Tsao N, Huang LY, Yen Y, Liu X, Lehman C, Wang YH, Tseng MC, Chen YJ, Ho YC, Chen CF, Chang ZF. The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells. Cell Reports. PMID 27452458 DOI: 10.1016/j.celrep.2016.06.094  0.433
2016 Zhang Z, Li Y, Huang L, Xiao Q, Chen X, Zhong J, Chen Y, Yang D, Han Z, Shu Y, Dai M, Cao K. Corrigendum to 'Let-7a suppresses macrophage infiltrations and malignant phenotype of Ewing sarcoma via STAT3/NF-κB positive regulatory circuit' [Cancer Lett. 374 (2016) 192-201]. Cancer Letters. PMID 27448532 DOI: 10.1016/j.canlet.2016.07.010  0.426
2016 Huo WY, Li Z, Chen YH, Xie X, Lan K, Liu J, Ren G, Li Y, Liu Y, Jiang X, Yang D, Li S, Guo L, Zhang H, Hou L, ... ... Huang L, et al. First Investigation on the Radiation Field of the Spherical Hohlraum. Physical Review Letters. 117: 025002. PMID 27447512 DOI: 10.1103/PhysRevLett.117.025002  0.387
2016 Sheen JM, Chen YC, Hsu MH, Tain YL, Yu HR, Huang LT. Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation. Frontiers in Cellular Neuroscience. 10: 167. PMID 27445694 DOI: 10.3389/Fncel.2016.00167  0.415
2016 Chen Y, Lu Z, Zhao J, Zou Z, Gong Y, Qu F, Bao Z, Qiu G, Song M, Zhang Q, Liu L, Hu M, Han X, Tian S, Zhao J, ... ... Huang L, et al. Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus from China. Antimicrobial Agents and Chemotherapy. PMID 27431231 DOI: 10.1128/AAC.01005-16  0.394
2016 Huang L, Chen YT, Li YX, Yu LS. Application of Chiral Ionic Liquid-Modified Gold Nanoparticles in the Chiral Recognition of Amino Acid Enantiomers. Applied Spectroscopy. PMID 27418633 DOI: 10.1177/0003702816645353  0.407
2016 Liang XE, Zhong C, Huang L, Yang S, Zhu Y, Chen Y, Hou J. Stepwise Application of Transient Elastography and Routine Biomarkers Optimizes Hepatitis B Cirrhosis Detection. Journal of Gastroenterology and Hepatology. PMID 27346683 DOI: 10.1111/jgh.13475  0.406
2016 Hou J, Huang L, Yang Z, Zhao Y, Deng C, Chen Y, Li X. Adsorption of ammonium on biochar prepared from giant reed. Environmental Science and Pollution Research International. PMID 27344654 DOI: 10.1007/s11356-016-7084-4  0.383
2016 Luo C, Miao L, Zhao Y, Musetti S, Wang Y, Shi K, Huang L. A novel cationic lipid with intrinsic antitumor activity to facilitate gene therapy of TRAIL DNA. Biomaterials. 102: 239-248. PMID 27344367 DOI: 10.1016/j.biomaterials.2016.06.030  0.791
2016 Chu Y, Zhu Y, Chen Y, Li W, Zhang Z, Liu D, Wang T, Ma J, Deng H, Liu ZJ, Ouyang S, Huang L. aKMT catalyzes extensive protein lysine methylation in the hyperthermophilic archaeon Sulfolobus islandicus but is dispensable for the growth of the organism. Molecular & Cellular Proteomics : McP. PMID 27329856 DOI: 10.1074/mcp.M115.057778  0.41
2016 Feng SW, Chen Y, Tsai WC, Chiou HC, Wu ST, Huang LC, Lin C, Hsieh CC, Yang YJ, Hueng DY. Overexpression of TELO2 decreases survival in human high-grade gliomas. Oncotarget. PMID 27329594 DOI: 10.18632/oncotarget.10021  0.431
2016 Huang L, Liu S, Lei Y, Wang K, Xu M, Chen Y, Liu B, Chen Y, Fu Q, Zhang P, Qin K, Cai Y, Fu S, Ge S, Yuan X. Systemic immune-inflammation index, thymidine phosphorylase and survival of localized gastric cancer patients after curative resection. Oncotarget. PMID 27283904 DOI: 10.18632/oncotarget.9923  0.449
2016 Zhao Y, Wang W, Guo S, Wang Y, Miao L, Xiong Y, Huang L. PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery. Nature Communications. 7: 11822. PMID 27264609 DOI: 10.1038/Ncomms11822  0.663
2016 Zhou X, Dong Y, Zhao J, Huang L, Ren X, Chen Y, Huang S, Liao B, Lei Y, Yan L, Jiang H. Genomic survey sequencing for development and validation of single-locus SSR markers in peanut (Arachis hypogaea L.). Bmc Genomics. 17: 420. PMID 27251557 DOI: 10.1186/s12864-016-2743-x  0.39
2016 Huang L, Wu B, Zhao J, Li H, Chen W, Zheng Y, Ren X, Chen Y, Zhou X, Lei Y, Liao B, Jiang H. Characterization and Transferable Utility of Microsatellite Markers in the Wild and Cultivated Arachis Species. Plos One. 11: e0156633. PMID 27243460 DOI: 10.1371/journal.pone.0156633  0.396
2016 Chen Y, Li C, Liu L, Guo F, Li S, Huang L, Sun C, Feng R. Serum metabonomics of NAFLD plus T2DM based on liquid chromatography-mass spectrometry. Clinical Biochemistry. PMID 27211699 DOI: 10.1016/j.clinbiochem.2016.05.016  0.394
2016 Chen Y, Huang L, Zhu J, Wu K. Effects of short-term glucocorticoid administration on bone mineral density, biomechanics and microstructure in rats' femur. Human & Experimental Toxicology. PMID 27193967 DOI: 10.1177/0960327116649674  0.385
2016 Chen YS, Li HR, Zhang W, Hua ZD, Lin XH, Lin MQ, Huang WS, Huang LP, Yu XL, Xu NL, Lin M, Xie BS, Shen XN, Xie JF, Wang Y, et al. Development of a bead-based suspension array for the detection of pathogens in acute respiratory tract infections. Experimental Biology and Medicine (Maywood, N.J.). PMID 27190247 DOI: 10.1177/1535370216647128  0.409
2016 Wei FJ, Tsai YC, Hsu YM, Chen YA, Huang CT, Wu HP, Huang LT, Lai MH, Kuang LY, Lo SF, Yu SM, Lin YR, Hsing YC. Lack of Genotype and Phenotype Correlation in a Rice T-DNA Tagged Line Is Likely Caused by Introgression in the Seed Source. Plos One. 11: e0155768. PMID 27186981 DOI: 10.1371/journal.pone.0155768  0.411
2016 Huang LY, Wang YC, Wu CC, Chen YC, Huang YL. Risk of Flood-Related Diseases of Eyes, Skin and Gastrointestinal Tract in Taiwan: A Retrospective Cohort Study. Plos One. 11: e0155166. PMID 27171415 DOI: 10.1371/journal.pone.0155166  0.383
2016 Huang L, Tang S, Peng L, Chen Y, Cheng J. Molecular Autopsy of Desmosomal Protein Plakophilin-2 in Sudden Unexplained Nocturnal Death Syndrome. Journal of Forensic Sciences. 61: 687-91. PMID 27122407 DOI: 10.1111/1556-4029.13027  0.389
2016 Huang L, Chen L, Huang P, Wu F, Tan L, Xiao S, Zhong W, Sun L, Chen Y. Triple Dipole Effect from Self-Assembled Small-Molecules for High Performance Organic Photovoltaics. Advanced Materials (Deerfield Beach, Fla.). PMID 27115312 DOI: 10.1002/adma.201600197  0.398
2016 Hu B, Zhang K, Li S, Li H, Yan Z, Huang L, Wu J, Han X, Jiang W, Mulatibieke T, Zheng L, Wan R, Wang X, Hu G. HIC1 attenuates invasion and metastasis by inhibiting the IL-6/STAT3 signalling pathway in human pancreatic cancer. Cancer Letters. PMID 27085461 DOI: 10.1016/j.canlet.2016.04.013  0.488
2016 Zhang HH, Lechuga TJ, Chen Y, Yang Y, Huang L, Chen DB. Quantitative Proteomics Analysis of VEGF-responsive Endothelial Protein S-Nitrosylation Using Stable Isotope Labeling of Amino Acids in Cell Culture (SILAC) and LC-MS/MS. Biology of Reproduction. PMID 27075618 DOI: 10.1095/biolreprod.116.139337  0.416
2016 Sheen JM, Hsieh CS, Tain YL, Li SW, Yu HR, Chen CC, Tiao MM, Chen YC, Huang LT. Programming Effects of Prenatal Glucocorticoid Exposure with a Postnatal High-Fat Diet in Diabetes Mellitus. International Journal of Molecular Sciences. 17. PMID 27070590 DOI: 10.3390/ijms17040533  0.394
2016 Wong TY, Chen YH, Liu SH, Solis MA, Yu CH, Chang CH, Huang LL. Differential Proteomic Analysis of Human Placenta-Derived Mesenchymal Stem Cells Cultured on Normal Tissue Culture Surface and Hyaluronan-Coated Surface. Stem Cells International. 2016: 2809192. PMID 27057169 DOI: 10.1155/2016/2809192  0.427
2016 Chen YH, Huang L, Wen ZH, Zhang C, Liang CH, Lai ST, Luo LZ, Wang YY, Wang GH. Skin whitening capability of shikimic acid pathway compound. European Review For Medical and Pharmacological Sciences. 20: 1214-1220. PMID 27049279  0.388
2016 Chen YD, Jin XQ, Yu MH, Fang Y, Huang LQ. Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial. Chinese Journal of Integrative Medicine. PMID 27048410 DOI: 10.1007/s11655-016-2453-x  0.4
2016 Gong X, Mao X, Chen Y, Huang L, Liu W, Huang X, Tan Z, Wang X, Zhang H, Wu W, Chene Q, Lic R. The changes of HRV in refractory epilepsy: The potential index to predict the onset of epilepsy in children. Journal of X-Ray Science and Technology. PMID 27002911 DOI: 10.3233/XST-160558  0.367
2016 Chen YW, Guo JY, Tzeng SY, Chou TC, Lin MJ, Huang LL, Yang CC, Hsu CK, Tseng SH. Toward reliable retrieval of functional information of papillary dermis using spatially resolved diffuse reflectance spectroscopy. Biomedical Optics Express. 7: 542-58. PMID 26977361 DOI: 10.1364/BOE.7.000542  0.389
2016 Chen Y, Anwar P, Huang L, Asvial M. Characterizing Nanoscale Transient Communication. Ieee Transactions On Nanobioscience. PMID 26955048 DOI: 10.1109/TNB.2016.2536645  0.395
2016 Fan Z, Wen T, Chen Y, Huang L, Lin W, Yin C, Tan W. Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes. Oxidative Medicine and Cellular Longevity. 2016: 6362812. PMID 26949448 DOI: 10.1155/2016/6362812  0.402
2016 Chen YZ, Li F, Xu H, Huang LC, Gu ZG, Sun ZY, Yan GJ, Zhu YJ, Tang C. [Spatio-temporal distribution of scrub typhus and related influencing factors in coastal beach area of Yancheng, China]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi. 37: 232-7. PMID 26917522  0.374
2016 Zhang Z, Li Y, Huang L, Xiao Q, Chen X, Zhong J, Chen Y, Yang D, Han Z, Shu Y, Dai M, Cao K. Let-7a suppresses macrophage infiltrations and malignant phenotype of ewing sarcoma via STAT3/ NF-κB positive regulatory circuit. Cancer Letters. PMID 26902422 DOI: 10.1016/j.canlet.2016.02.027  0.477
2016 Wu L, Chen Y, Gao H, Yin J, Huang L. Cadmium-induced cell killing in Sacharomyces cerevisiae involves increases in intracellular NO levels. Fems Microbiology Letters. PMID 26872495 DOI: 10.1093/femsle/fnw032  0.441
2016 Huang L, Xi Z, Wang C, Zhang Y, Yang Z, Zhang S, Chen Y, Zuo Z. Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation. Scientific Reports. 6: 20105. PMID 26830171 DOI: 10.1038/srep20105  0.411
2016 Lin YC, Chen YF, Tseng LS, Lee YH, Morris-Natschke SL, Kuo SC, Yang NS, Lee KH, Huang LJ. Synthesis and structure-activity relationship studies of novel 3,9-substituted α-carboline derivatives with high cytotoxic activity against colorectal cancer cells. European Journal of Medicinal Chemistry. 110: 98-114. PMID 26820553 DOI: 10.1016/j.ejmech.2016.01.004  0.431
2016 Chen W, Jiao Y, Cheng L, Huang L, Liao B, Tang M, Ren X, Zhou X, Chen Y, Jiang H. Quantitative trait locus analysis for pod- and kernel-related traits in the cultivated peanut (Arachis hypogaea L.). Bmc Genetics. 17: 25. PMID 26810040 DOI: 10.1186/s12863-016-0337-x  0.384
2016 Huang L, Shen C, Chen Y, Yan H, Cheng Z, Zhu Q. Simotinib as a modulator of P-glycoprotein: substrate, inhibitor, or inducer? Anti-Cancer Drugs. PMID 26766493 DOI: 10.1097/CAD.0000000000000332  0.419
2016 Chen Y, Huang L, Zhang H, Diao X, Zhao S, Zhou W. Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage. Molecular Neurobiology. PMID 26742518 DOI: 10.1007/s12035-015-9629-9  0.403
2016 Wei FJ, Tsai YC, Wu HP, Huang LT, Chen YC, Chen YF, Wu CC, Tseng YT, Hsing YI. Both Hd1 and Ehd1 are important for artificial selection of flowering time in cultivated rice. Plant Science : An International Journal of Experimental Plant Biology. 242: 187-94. PMID 26566836 DOI: 10.1016/j.plantsci.2015.09.005  0.407
2016 Xu YF, Xu GL, Su H, Chen Y, Fang JC, Wang Q, Huang L, Li JT, Sun SG. Porous MnO/C of composite nanostructure consisting of nanorods and nano-octahedra as anode of lithium ion batteries with enhanced electrochemical performances Journal of Alloys and Compounds. 676: 156-163. DOI: 10.1016/J.Jallcom.2016.03.151  0.389
2015 Zheng LH, Huang LY, Chen Y, Lin SE, Huang BL. [Determination of Nucleosides and Nucleobases in Natural, Cultured and Tissue Culture Anoectochilus roxburghii Using LC-MS]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials. 38: 2269-73. PMID 27356374  0.375
2015 Li ZX, Diao JY, Huang LD, Chen YF, Liu DG, Xu ZW. [Removal of Phosphate by Calcite in Open-System]. Huan Jing Ke Xue= Huanjing Kexue / [Bian Ji, Zhongguo Ke Xue Yuan Huan Jing Ke Xue Wei Yuan Hui "Huan Jing Ke Xue" Bian Ji Wei Yuan Hui.]. 36: 4523-30. PMID 27011989  0.388
2015 Chen Y, Huang L, Zhang H, Klebanoff M, Yang Z, Zhang J. Racial disparity in placental pathology in the collaborative perinatal project. International Journal of Clinical and Experimental Pathology. 8: 15042-54. PMID 26823843  0.378
2015 Sun Z, Luo B, Liu Z, Huang L, Liu B, Ma T, Gao B, Liu ZH, Chen YF, Huang JH, Luo Z. Effect of perfluorotributylamine-enriched alginate on nucleus pulposus cell: Implications for intervertebral disc regeneration. Biomaterials. 82: 34-47. PMID 26741882 DOI: 10.1016/j.biomaterials.2015.12.013  0.435
2015 Lin QF, Qiu CS, Wang SL, Huang LF, Chen ZY, Chen Y, Chen G. A Cross-sectional Study of the Relationship Between Habitual Tea Consumption and Arterial Stiffness. Journal of the American College of Nutrition. 1-8. PMID 26709673 DOI: 10.1080/07315724.2015.1058197  0.365
2015 Huang L, Luo X, Shao J, Yan H, Qiu Y, Ke P, Zheng W, Xu B, Li W, Sun D, Cao D, Chen C, Zhuo F, Lin X, Tang F, ... Huang L, et al. Epidemiology and characteristics of the dengue outbreak in Guangdong, Southern China, in 2014. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. PMID 26700953 DOI: 10.1007/s10096-015-2540-5  0.393
2015 Zhu S, Huang L, Chen F, Chen Y. [Application of the Mandarin Tone Identification Test (MTIT) in children with hearing impairment]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 50: 651-6. PMID 26696203  0.377
2015 Chen Z, Qian Y, Liu S, Huang L, Xu S, Yin W, Chen Y, Wu H, Wang G. [Onset time and efficacy of sublingual immunotherapy with Dermatophagoides farinae drops in children with allergic rhinitis]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 50: 622-6. PMID 26696197  0.387
2015 Chen Y, Cheng X, Mo F, Huang L, Wu Z, Wu Y, Xu L, Fu F. Ultra-sensitive speciation analysis of mercury by CE-ICP-MS together with field-amplified sample stacking injection and dispersive solid-phase extraction. Electrophoresis. PMID 26643127 DOI: 10.1002/elps.201500460  0.387
2015 Zeng Q, Wang Q, Chen X, Xia K, Tang J, Zhou X, Cheng Y, Chen Y, Huang L, Xiang H, Cao K, Zhou J. Analysis of lncRNAs expression in UVB-induced stress responses of melanocytes. Journal of Dermatological Science. PMID 26596215 DOI: 10.1016/j.jdermsci.2015.10.019  0.402
2015 Tseng HM, Lee CH, Chen YJ, Hsu HH, Huang LY, Huang JL. Developing a measure of medication-related quality of life for people with polypharmacy. Quality of Life Research : An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. PMID 26584811 DOI: 10.1007/s11136-015-1177-2  0.369
2015 Huang L, Chen Y, Chen Y, Wu H. Centrifugation-assisted single-cell trapping (CAScT) in a truncated cone-shaped microwell array (TCMA) chip for the real-time observation of cellular apoptosis. Analytical Chemistry. PMID 26579559 DOI: 10.1021/Acs.Analchem.5B03031  0.441
2015 Chang D, Gao Y, Wang L, Liu G, Chen Y, Wang T, Tao W, Mei L, Huang L, Zeng X. Polydopamine-based surface modification of mesoporous silica nanoparticles as pH-sensitive drug delivery vehicles for cancer therapy. Journal of Colloid and Interface Science. 463: 279-287. PMID 26550786 DOI: 10.1016/j.jcis.2015.11.001  0.473
2015 Chen Y, Li G, Huang LY. p38 MAPK mediates glial P2X7R-neuronal P2Y1R inhibitory control of P2X3R expression in dorsal root ganglion neurons. Molecular Pain. 11: 68. PMID 26542462 DOI: 10.1186/S12990-015-0073-7  0.411
2015 Chen Y, Sun J, Huang LC, Xu H, Zhao Z. Classification of Cancer Primary Sites Using Machine Learning and Somatic Mutations. Biomed Research International. 2015: 491502. PMID 26539502 DOI: 10.1155/2015/491502  0.445
2015 Wang Y, Cai J, Zeng X, Chen Y, Yan W, Ouyang Y, Xiao D, Zeng Z, Huang L, Liu A. Downregulation of toll-like receptor 4 induces suppressive effects on hepatitis B virus-related hepatocellular carcinoma via ERK1/2 signaling. Bmc Cancer. 15: 821. PMID 26514586 DOI: 10.1186/s12885-015-1866-9  0.447
2015 Wang F, Chen Y, Huang L, Liu T, Huang Y, Zhao J, Wang X, Yang K, Ma S, Huang L, To KK, Gu Y, Fu L. Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/P-glycoprotein-overexpressing cancer cells. Oncotarget. PMID 26506420 DOI: 10.18632/oncotarget.5813  0.493
2015 Li ZX, Huang LD, Chen YF, Miao Y, Liu DG, Xu ZW. [Sorption of o-Phthalate onto Calcite in Open-System]. Huan Jing Ke Xue= Huanjing Kexue / [Bian Ji, Zhongguo Ke Xue Yuan Huan Jing Ke Xue Wei Yuan Hui "Huan Jing Ke Xue" Bian Ji Wei Yuan Hui.]. 36: 2547-53. PMID 26489324  0.386
2015 Huang LC, Chung WF, Liu SW, Chang PY, Chen LF, Wu JC, Chen YC, Huang WC, Liu L, Cheng H, Lo SS. Lower Risk of Stroke after Deformity Surgery: Long Term Benefit Demonstrated by a National Cohort Study. International Journal of Environmental Research and Public Health. 12: 12618-12627. PMID 26473897 DOI: 10.3390/ijerph121012618  0.375
2015 Mu PF, Lee MY, Sheng CC, Tung PC, Huang LY, Chen YW. The experiences of family members in the year following the diagnosis of a child or adolescent with cancer: a qualitative systematic review. Jbi Database of Systematic Reviews and Implementation Reports. 13: 293-329. PMID 26455612 DOI: 10.11124/jbisrir-2015-1698  0.395
2015 Ni C, Huang L, Chen Y, He M, Hu Y, Liu S, Fang X, Li J, Sun Q, Wang X. Implication of cell-in-cell structures in the transmission of HIV to epithelial cells. Cell Research. PMID 26427717 DOI: 10.1038/cr.2015.119  0.407
2015 Yan W, Xu Y, Huang L, Chen Y. Controllable and Reversible Dispersiblity of Graphene Materials by a Generic Organometallic Functionalization. Journal of Nanoscience and Nanotechnology. 15: 2032-9. PMID 26413617 DOI: 10.1166/Jnn.2015.9155  0.386
2015 Chen YS, Li XQ, Li HR, Yu XL, Lu FF, Huang LP, Miao Y, Wang GQ, Lin X, Lian SQ, Lin YH, Zhang XE, Liu T, Wu YL. Spirometric prediction equations and the relationship between metabolic syndrome and spirometric parameters from an island in Fujian, China. The Clinical Respiratory Journal. PMID 26364731 DOI: 10.1111/crj.12381  0.381
2015 Zhao DJ, Chen Y, Wang ZY, Xue L, Mao TL, Liu YM, Wang ZY, Huang L. High-resolution non-contact measurement of the electrical activity of plants in situ using optical recording. Scientific Reports. 5: 13425. PMID 26333536 DOI: 10.1038/srep13425  0.391
2015 Lu YM, Pan J, Zhang WN, Hui AL, Guo WQ, Huang L, Zhu QJ, Chen Y. Synthesis, in silico and in vivo blood brain barrier permeability of ginkgolide B cinnamate. Fitoterapia. 106: 110-114. PMID 26327588 DOI: 10.1016/j.fitote.2015.08.012  0.432
2015 Yuh JY, Lin SW, Huang LJ, Fung HS, Lee LL, Chen YJ, Cheng CP, Chin YY, Lin HJ. Upgrade of beamline BL08B at Taiwan Light Source from a photon-BPM to a double-grating SGM beamline. Journal of Synchrotron Radiation. 22: 1312-8. PMID 26289286 DOI: 10.1107/S1600577515014009  0.382
2015 Chen WH, Lecaros RL, Tseng YC, Huang L, Hsu YC. Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer. Cancer Letters. 359: 65-74. PMID 25596376 DOI: 10.1016/j.canlet.2014.12.052  0.592
2015 He B, Gao SQ, Huang LD, Huang YH, Zhang QY, Zhou MT, Shi HQ, Song QT, Shan YF. MicroRNA-155 promotes the proliferation and invasion abilities of colon cancer cells by targeting quaking. Molecular Medicine Reports. 11: 2355-9. PMID 25420938 DOI: 10.3892/mmr.2014.2994  0.397
2015 Chen Y, Gao DY, Huang L. In vivo delivery of miRNAs for cancer therapy: challenges and strategies. Advanced Drug Delivery Reviews. 81: 128-41. PMID 24859533 DOI: 10.1016/J.Addr.2014.05.009  0.774
2014 Miao L, Guo S, Zhang J, Kim WY, Huang L. Nanoparticles with Precise Ratiometric Co-Loading and Co-Delivery of Gemcitabine Monophosphate and Cisplatin for Treatment of Bladder Cancer. Advanced Functional Materials. 24: 6601-6611. PMID 25395922 DOI: 10.1002/Adfm.201401076  0.663
2014 He B, Huang Y, Li P, Ye X, Lin F, Huang L, Gao S, Shi H, Shan Y. A rare case of primary chondrosarcoma arising from the sternum: A case report. Oncology Letters. 8: 2233-2236. PMID 25289102 DOI: 10.3892/ol.2014.2453  0.327
2014 Tseng YC, Kan LP, Huang LY, Yin T, Yang YS, Lin JC, Siu LK. Successful treatment of a patient with ventriculoperitoneal shunt-associated meningitis caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae. The Tohoku Journal of Experimental Medicine. 233: 301-5. PMID 25142281 DOI: DN/JST.JSTAGE/tjem/233.301  0.487
2014 Guo S, Wang Y, Miao L, Xu Z, Lin CH, Huang L. Turning a water and oil insoluble cisplatin derivative into a nanoparticle formulation for cancer therapy. Biomaterials. 35: 7647-53. PMID 24920436 DOI: 10.1016/J.Biomaterials.2014.05.045  0.646
2014 Guo S, Lin CM, Xu Z, Miao L, Wang Y, Huang L. Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation. Acs Nano. 8: 4996-5009. PMID 24720540 DOI: 10.1021/Nn5010815  0.669
2014 Zhang J, Miao L, Guo S, Zhang Y, Zhang L, Satterlee A, Kim WY, Huang L. Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model. Journal of Controlled Release : Official Journal of the Controlled Release Society. 182: 90-6. PMID 24637468 DOI: 10.1016/J.Jconrel.2014.03.016  0.649
2014 Tseng YC, Xu Z, Guley K, Yuan H, Huang L. Lipid-calcium phosphate nanoparticles for delivery to the lymphatic system and SPECT/CT imaging of lymph node metastases. Biomaterials. 35: 4688-98. PMID 24613050 DOI: 10.1016/j.biomaterials.2014.02.030  0.527
2014 Guo S, Miao L, Wang Y, Huang L. Unmodified drug used as a material to construct nanoparticles: delivery of cisplatin for enhanced anti-cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 174: 137-42. PMID 24280262 DOI: 10.1016/J.Jconrel.2013.11.019  0.623
2014 Guo S, Huang L. Nanoparticles containing insoluble drug for cancer therapy. Biotechnology Advances. 32: 778-88. PMID 24113214 DOI: 10.1016/J.Biotechadv.2013.10.002  0.644
2013 Zhang LL, Huang LH, Zhang ZX, Hao DJ, He BR. Compatibility of olfactory ensheathing cells with functionalized self-assembling peptide scaffold in vitro. Chinese Medical Journal. 126: 3891-6. PMID 24157152  0.329
2013 Li R, Huang L, Li J, Mo Z, He B, Wang Y, Wu X, Minutello M, Guinet-Morlot F, Pichon S. A next-generation, serum-free, highly purified Vero cell rabies vaccine is safe and as immunogenic as the reference vaccine Verorab® when administered according to a post-exposure regimen in healthy children and adults in China. Vaccine. 31: 5940-7. PMID 24148575 DOI: 10.1016/j.vaccine.2013.10.043  0.313
2013 Guo S, Wang Y, Miao L, Xu Z, Lin CM, Zhang Y, Huang L. Lipid-coated Cisplatin nanoparticles induce neighboring effect and exhibit enhanced anticancer efficacy. Acs Nano. 7: 9896-904. PMID 24083505 DOI: 10.1021/Nn403606M  0.662
2013 Tseng YC, Yang A, Huang L. How does the cell overcome LCP nanoparticle-induced calcium toxicity? Molecular Pharmaceutics. 10: 4391-5. PMID 24032396 DOI: 10.1021/mp400028m  0.491
2013 Xu Z, Ramishetti S, Tseng YC, Guo S, Wang Y, Huang L. Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 259-65. PMID 24004885 DOI: 10.1016/J.Jconrel.2013.08.021  0.738
2013 Wang Y, Zhang L, Guo S, Hatefi A, Huang L. Incorporation of histone derived recombinant protein for enhanced disassembly of core-membrane structured liposomal nanoparticles for efficient siRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 179-89. PMID 23978682 DOI: 10.1016/J.Jconrel.2013.08.015  0.626
2013 Zhang Y, Peng L, Mumper RJ, Huang L. Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy. Biomaterials. 34: 8459-68. PMID 23932296 DOI: 10.1016/J.Biomaterials.2013.07.050  0.337
2013 Wang Y, Xu Z, Guo S, Zhang L, Sharma A, Robertson GP, Huang L. Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1919-29. PMID 23774794 DOI: 10.1038/Mt.2013.135  0.632
2013 GUO S, MIAO L, HUANG L. Lipid Coated Calcium Phosphate Nanoparticles for Drug Delivery Acta Biophysica Sinica. 29: 823. DOI: 10.3724/SP.J.1260.2013.30165  0.612
2012 Liu Y, Tseng YC, Huang L. Biodistribution studies of nanoparticles using fluorescence imaging: a qualitative or quantitative method? Pharmaceutical Research. 29: 3273-7. PMID 22806405 DOI: 10.1007/s11095-012-0818-1  0.523
2012 Vasievich EA, Ramishetti S, Zhang Y, Huang L. Trp2 peptide vaccine adjuvanted with (R)-DOTAP inhibits tumor growth in an advanced melanoma model. Molecular Pharmaceutics. 9: 261-8. PMID 22142394 DOI: 10.1021/Mp200350N  0.792
2012 Guo X, Huang L. Recent advances in nonviral vectors for gene delivery. Accounts of Chemical Research. 45: 971-9. PMID 21870813 DOI: 10.1021/Ar200151M  0.382
2012 Chung C, Wang Y, Sheng W, Tseng Y, Dick T, Huang L, Robertson G. Abstract B10: Overcoming resistance to B-Raf targeting agents using LPD nanotechnology Clinical Cancer Research. 18: B10-B10. DOI: 10.1158/1078-0432.Mechres-B10  0.545
2011 Huang L, Liu Y. In vivo delivery of RNAi with lipid-based nanoparticles. Annual Review of Biomedical Engineering. 13: 507-30. PMID 21639780 DOI: 10.1146/Annurev-Bioeng-071910-124709  0.345
2011 Vasievich EA, Huang L. The suppressive tumor microenvironment: a challenge in cancer immunotherapy. Molecular Pharmaceutics. 8: 635-41. PMID 21545153 DOI: 10.1021/Mp1004228  0.804
2011 Vasievich EA, Chen W, Huang L. Enantiospecific adjuvant activity of cationic lipid DOTAP in cancer vaccine. Cancer Immunology, Immunotherapy : Cii. 60: 629-38. PMID 21267720 DOI: 10.1007/S00262-011-0970-1  0.784
2011 Guo S, Huang L. Nanoparticles Escaping RES and Endosome: Challenges for siRNA Delivery for Cancer Therapy Journal of Nanomaterials. 2011: 1-12. DOI: 10.1155/2011/742895  0.656
2010 Bauman JA, Li SD, Yang A, Huang L, Kole R. Anti-tumor activity of splice-switching oligonucleotides. Nucleic Acids Research. 38: 8348-56. PMID 20719743 DOI: 10.1093/Nar/Gkq731  0.518
2010 Chen Y, Bathula SR, Yang Q, Huang L. Targeted nanoparticles deliver siRNA to melanoma. The Journal of Investigative Dermatology. 130: 2790-8. PMID 20686495 DOI: 10.1038/Jid.2010.222  0.578
2010 Chen Y, Zhu X, Zhang X, Liu B, Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1650-6. PMID 20606648 DOI: 10.1038/Mt.2010.136  0.517
2010 Chen Y, Bathula SR, Li J, Huang L. Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. The Journal of Biological Chemistry. 285: 22639-50. PMID 20460382 DOI: 10.1074/Jbc.M110.125906  0.521
2010 Li SD, Huang L. Stealth nanoparticles: high density but sheddable PEG is a key for tumor targeting. Journal of Controlled Release : Official Journal of the Controlled Release Society. 145: 178-81. PMID 20338200 DOI: 10.1016/j.jconrel.2010.03.016  0.51
2010 Chen Y, Wu JJ, Huang L. Nanoparticles targeted with NGR motif deliver c-myc siRNA and doxorubicin for anticancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 828-34. PMID 20068551 DOI: 10.1038/Mt.2009.291  0.546
2010 Li J, Chen YC, Tseng YC, Mozumdar S, Huang L. Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 416-21. PMID 19919845 DOI: 10.1016/j.jconrel.2009.11.008  0.674
2009 Tseng YC, Huang L. Self-assembled lipid nanomedicines for siRNA tumor targeting. Journal of Biomedical Nanotechnology. 5: 351-63. PMID 20055081  0.593
2009 Li SD, Huang L. Nanoparticles evading the reticuloendothelial system: role of the supported bilayer. Biochimica Et Biophysica Acta. 1788: 2259-66. PMID 19595666 DOI: 10.1016/j.bbamem.2009.06.022  0.51
2009 Tseng YC, Mozumdar S, Huang L. Lipid-based systemic delivery of siRNA. Advanced Drug Delivery Reviews. 61: 721-31. PMID 19328215 DOI: 10.1016/J.Addr.2009.03.003  0.598
2009 Chen Y, Sen J, Bathula SR, Yang Q, Fittipaldi R, Huang L. Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells. Molecular Pharmaceutics. 6: 696-705. PMID 19267451 DOI: 10.1021/Mp800136V  0.534
2008 Chen Y, Huang L. Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy. Expert Opinion On Drug Delivery. 5: 1301-11. PMID 19040393 DOI: 10.1517/17425240802568505  0.531
2008 Li SD, Huang L. Targeted delivery of siRNA by nonviral vectors: lessons learned from recent advances. Current Opinion in Investigational Drugs (London, England : 2000). 9: 1317-23. PMID 19037838  0.53
2008 Chono S, Li SD, Conwell CC, Huang L. An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor. Journal of Controlled Release : Official Journal of the Controlled Release Society. 131: 64-9. PMID 18674578 DOI: 10.1016/j.jconrel.2008.07.006  0.529
2008 Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Molecular Pharmaceutics. 5: 496-504. PMID 18611037 DOI: 10.1021/Mp800049W  0.545
2008 Li SD, Chono S, Huang L. Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 942-6. PMID 18388916 DOI: 10.1038/mt.2008.51  0.51
2008 Li SD, Chono S, Huang L. Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 126: 77-84. PMID 18083264 DOI: 10.1016/j.jconrel.2007.11.002  0.515
2008 Li SD, Chen YC, Hackett MJ, Huang L. Tumor-targeted delivery of siRNA by self-assembled nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 163-9. PMID 17923843 DOI: 10.1038/Sj.Mt.6300323  0.663
2007 Li SD, Huang L. Non-viral is superior to viral gene delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 123: 181-3. PMID 17935817 DOI: 10.1016/j.jconrel.2007.09.004  0.463
2006 Li SD, Huang L. Surface-modified LPD nanoparticles for tumor targeting. Annals of the New York Academy of Sciences. 1082: 1-8. PMID 17145918 DOI: 10.1196/annals.1348.001  0.562
2006 Li SD, Huang L. Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells. Molecular Pharmaceutics. 3: 579-88. PMID 17009857 DOI: 10.1021/mp060039w  0.555
2006 Li SD, Huang L. Gene therapy progress and prospects: non-viral gene therapy by systemic delivery. Gene Therapy. 13: 1313-9. PMID 16953249 DOI: 10.1038/sj.gt.3302838  0.525
2006 Holder E, Griesenbach U, Li S, Huang L, Rogers DF, Jeffery PK, Geddes DM, Alton EW. Intravenously administered oligonucleotides can be delivered to conducting airway epithelium via the bronchial circulation. Gene Therapy. 13: 1628-38. PMID 16791284 DOI: 10.1038/Sj.Gt.3302811  0.402
2006 Zhang JS, Liu F, Conwell CC, Tan Y, Huang L. Mechanistic studies of sequential injection of cationic liposome and plasmid DNA. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 429-37. PMID 16242997 DOI: 10.1016/J.Ymthe.2005.08.021  0.312
2006 Banerjee R, Huang L. Vector System: Plasmid DNA Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200500030  0.36
2005 Vangasseri DP, Han SJ, Huang L. Lipid-protamine-DNA-mediated antigen delivery. Current Drug Delivery. 2: 401-6. PMID 16305443 DOI: 10.2174/156720105774370168  0.325
2005 Conwell CC, Huang L. Recent Advances in Non-viral Gene Delivery. Advances in Genetics. 53: 1-18. PMID 16243058 DOI: 10.1016/S0065-2660(05)53001-3  0.341
2005 Wilson A, Zhou W, Champion HC, Alber S, Tang ZL, Kennel S, Watkins S, Huang L, Pitt B, Li S. Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 510-8. PMID 15953766 DOI: 10.1016/J.Ymthe.2005.04.005  0.308
2005 Lemoine JL, Farley R, Huang L. Mechanism of efficient transfection of the nasal airway epithelium by hypotonic shock. Gene Therapy. 12: 1275-82. PMID 15889135 DOI: 10.1038/Sj.Gt.3302548  0.308
2005 Cui Z, Huang L. Liposome-polycation-DNA (LPD) particle as a carrier and adjuvant for protein-based vaccines: therapeutic effect against cervical cancer. Cancer Immunology, Immunotherapy : Cii. 54: 1180-90. PMID 15846491 DOI: 10.1007/S00262-005-0685-2  0.337
2005 Cui Z, Han SJ, Vangasseri DP, Huang L. Immunostimulation mechanism of LPD nanoparticle as a vaccine carrier. Molecular Pharmaceutics. 2: 22-8. PMID 15804174 DOI: 10.1021/Mp049907K  0.332
2005 Zhang JS, Liu F, Huang L. Implications of pharmacokinetic behavior of lipoplex for its inflammatory toxicity. Advanced Drug Delivery Reviews. 57: 689-98. PMID 15757755 DOI: 10.1016/J.Addr.2004.12.004  0.325
2004 Banerjee R, Tyagi P, Li S, Huang L. Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells. International Journal of Cancer. Journal International Du Cancer. 112: 693-700. PMID 15382053 DOI: 10.1002/Ijc.20452  0.455
2004 Liu F, Shollenberger LM, Huang L. Non-immunostimulatory nonviral vectors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1779-81. PMID 15364893 DOI: 10.1096/Fj.04-2187Fje  0.339
2004 Li Z, Huang L. Sustained delivery and expression of plasmid DNA based on biodegradable polyester, poly(D,L-lactide-co-4-hydroxy-L-proline). Journal of Controlled Release : Official Journal of the Controlled Release Society. 98: 437-46. PMID 15312999 DOI: 10.1016/J.Jconrel.2004.05.013  0.303
2004 Cui Z, Han SJ, Huang L. Coating of mannan on LPD particles containing HPV E7 peptide significantly enhances immunity against HPV-positive tumor. Pharmaceutical Research. 21: 1018-25. PMID 15212168 DOI: 10.1023/B:Pham.0000029292.66792.4F  0.348
2004 Liu F, Lei J, Vollmer R, Huang L. Mechanism of liver gene transfer by mechanical massage Molecular Therapy. 9: 452-457. PMID 15006613 DOI: 10.1016/J.Ymthe.2003.12.003  0.309
2004 Stabile LP, Lyker JS, Huang L, Siegfried JM. Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy. Gene Therapy. 11: 325-35. PMID 14737093 DOI: 10.1038/Sj.Gt.3302169  0.336
2004 Tyagi P, Chancellor MB, Li Z, De Groat WC, Yoshimura N, Fraser MO, Huang L. Urodynamic and immunohistochemical evaluation of intravesical capsaicin delivery using thermosensitive hydrogel and liposomes. The Journal of Urology. 171: 483-9. PMID 14665960 DOI: 10.1097/01.Ju.0000102360.11785.D7  0.304
2003 Zhang JS, Li S, Huang L. Cationic liposome-protamine-DNA complexes for gene delivery. Methods in Enzymology. 373: 332-42. PMID 14714413 DOI: 10.1016/S0076-6879(03)73021-3  0.317
2003 Yuan X, Ma Z, Zhou W, Niidome T, Alber S, Huang L, Watkins S, Li S. Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium. Biochemical and Biophysical Research Communications. 302: 6-11. PMID 12593839 DOI: 10.1016/S0006-291X(03)00058-5  0.409
2003 Dileo J, Miller TE, Chesnoy S, Huang L. Gene transfer to subdermal tissues via a new gene gun design. Human Gene Therapy. 14: 79-87. PMID 12573061 DOI: 10.1089/10430340360464732  0.323
2003 Liang KW, Liu F, Huang L. Targeted gene delivery: the role of peptide nucleic acid International Journal of Peptide Research and Therapeutics. 10: 161-167. DOI: 10.1007/S10989-004-4922-X  0.336
2003 Banerjee R, Huang L. Plasmid DNA–Mediated Gene Therapy Burger's Medicinal Chemistry and Drug Discovery. 641-667. DOI: 10.1002/0471266949.Bmc073  0.354
2002 Tan Y, Zhang JS, Huang L. Codelivery of NF-kappaB decoy-related oligodeoxynucleotide improves LPD-mediated systemic gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 804-12. PMID 12498776 DOI: 10.1006/Mthe.2002.0811  0.322
2002 Niidome T, Huang L. Gene therapy progress and prospects: nonviral vectors. Gene Therapy. 9: 1647-52. PMID 12457277 DOI: 10.1038/Sj.Gt.3301923  0.347
2002 Ueno NT, Bartholomeusz C, Xia W, Anklesaria P, Bruckheimer EM, Mebel E, Paul R, Li S, Yo GH, Huang L, Hung MC. Systemic gene therapy in human xenograft tumor models by liposomal delivery of the E1A gene. Cancer Research. 62: 6712-6. PMID 12438271  0.411
2002 Zeng Q, Kanter PM, Dhir R, Gooding WE, Huang L, Grandis JR. Lack of toxicity of EGFR antisense gene therapy. Journal of Experimental Therapeutics & Oncology. 2: 174-86. PMID 12415634 DOI: 10.1046/J.1359-4117.2002.01033.X  0.346
2002 Ma Z, Zhang J, Alber S, Dileo J, Negishi Y, Stolz D, Watkins S, Huang L, Pitt B, Li S. Lipid-mediated delivery of oligonucleotide to pulmonary endothelium. American Journal of Respiratory Cell and Molecular Biology. 27: 151-9. PMID 12151306 DOI: 10.1165/Ajrcmb.27.2.4653  0.405
2002 Liu F, Huang L. Electric gene transfer to the liver following systemic administration of plasmid DNA. Gene Therapy. 9: 1116-9. PMID 12140740 DOI: 10.1038/Sj.Gt.3301733  0.328
2002 Liu F, Huang L. Noninvasive gene delivery to the liver by mechanical massage. Hepatology (Baltimore, Md.). 35: 1314-9. PMID 12029616 DOI: 10.1053/Jhep.2002.33467  0.32
2002 Tan Y, Whitmore M, Li S, Frederik P, Huang L. LPD nanoparticles--novel nonviral vector for efficient gene delivery. Methods in Molecular Medicine. 69: 73-81. PMID 11987799 DOI: 10.1385/1-59259-141-8:073  0.322
2002 Lui VW, He Y, Falo L, Huang L. Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor. Human Gene Therapy. 13: 177-85. PMID 11812275 DOI: 10.1089/10430340252769716  0.367
2002 Chesnoy S, Huang L. Enhanced cutaneous gene delivery following intradermal injection of naked DNA in a high ionic strength solution. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 57-62. PMID 11786046 DOI: 10.1006/Mthe.2001.0511  0.313
2002 Whitmore MM, Li S, Falo L, Huang L. Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses. Cancer Immunology, Immunotherapy : Cii. 50: 503-14. PMID 11776372 DOI: 10.1007/S002620100227  0.443
2002 Liu F, Huang L. Development of non-viral vectors for systemic gene delivery. Journal of Controlled Release. 78: 259-266. PMID 11772466 DOI: 10.1016/S0168-3659(01)00494-1  0.323
2002 Chesnoy S, Durand D, Doucet J, Stolz DB, Huang L. Improved DNA/emulsion complex stabilized by poly(ethylene glycol) conjugated phospholipid. Pharmaceutical Research. 18: 1480-4. PMID 11697477 DOI: 10.1023/A:1012221310136  0.307
2001 Whitemore M, Li S, Huang L. Liposome vectors for in vivo gene delivery. Current Protocols in Human Genetics. Unit 12.8. PMID 18428252 DOI: 10.1002/0471142905.Hg1208S20  0.434
2001 Hofman C, Dileo J, Li Z, Li S, Huang L. Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activity. Gene Therapy. 8: 71-74. PMID 11402304 DOI: 10.1038/Sj.Gt.3301373  0.413
2001 Nishikawa M, Huang L. Nonviral Vectors in the New Millennium: Delivery Barriers in Gene Transfer Human Gene Therapy. 12: 861-870. PMID 11387052 DOI: 10.1089/104303401750195836  0.352
2001 Tan Y, Liu F, Li Z, Li S, Huang L. Sequential Injection of Cationic Liposome and Plasmid DNA Effectively Transfects the Lung with Minimal Inflammatory Toxicity Molecular Therapy. 3: 673-682. PMID 11356072 DOI: 10.1006/Mthe.2001.0311  0.412
2001 Yang J, Chen S, Huang L, Michalopoulos GK, Liu Y. Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth Hepatology. 33: 848-859. PMID 11283849 DOI: 10.1053/Jhep.2001.23438  0.313
2001 Wu X, He Y, Falo LD, Hui KM, Huang L. Regression of human mammary adenocarcinoma by systemic administration of a recombinant gene encoding the hFlex-TRAIL fusion protein. Molecular Therapy. 3: 368-374. PMID 11273779 DOI: 10.1006/Mthe.2001.0280  0.372
2001 Lui VW, He Y, Goyaland K, Huang L. Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma. Molecular Therapy. 3: 169-177. PMID 11237673 DOI: 10.1006/Mthe.2000.0241  0.307
2000 Endo S, Zeng Q, Burke NA, He Y, Melhem MF, Watkins SF, Lango MN, Drenning SD, Huang L, Rubin Grandis J. TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo. Gene Therapy. 7: 1906-14. PMID 11127578 DOI: 10.1038/Sj.Gt.3301315  0.329
2000 Chesnoy S, Huang L. Structure and Function of Lipid-DNA Complexes for Gene Delivery Annual Review of Biophysics and Biomolecular Structure. 29: 27-47. PMID 10940242 DOI: 10.1146/Annurev.Biophys.29.1.27  0.343
2000 Liang KW, Hoffman EP, Huang L. Targeted Delivery of Plasmid DNA to Myogenic Cells via Transferrin-Conjugated Peptide Nucleic Acid Molecular Therapy. 1: 236-243. PMID 10933939 DOI: 10.1006/Mthe.2000.0043  0.332
2000 Grandis JR, Drenning SD, Zeng Q, Watkins SC, Melhem MF, Endo S, Johnson DE, Huang L, He Y, Kim JD. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 97: 4227-32. PMID 10760290 DOI: 10.1073/Pnas.97.8.4227  0.352
2000 Li S, Tan Y, Viroonchatapan E, Pitt BR, Huang L. Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L504-11. PMID 10710522 DOI: 10.1152/Ajplung.2000.278.3.L504  0.434
2000 Li B, Li S, Tan Y, Stolz DB, Watkins SC, Block LH, Huang L. Lyophilization of cationic lipid-protamine-DNA (LPD) complexes. Journal of Pharmaceutical Sciences. 89: 355-364. PMID 10707016 DOI: 10.1002/(Sici)1520-6017(200003)89:3<355::Aid-Jps7>3.0.Co;2-H  0.414
2000 Li S, Huang L. Nonviral gene therapy: promises and challenges. Gene Therapy. 7: 31-34. PMID 10680013 DOI: 10.1038/Sj.Gt.3301110  0.388
2000 Xing X, Wang SC, Xia W, Zou Y, Shao R, Kwong KY, Yu Z, Zhang S, Miller S, Huang L, Hung MC. The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis. Nature Medicine. 6: 189-95. PMID 10655108 DOI: 10.1038/72294  0.363
1999 Whitmore M, Li S, Huang L. LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Therapy. 6: 1867-1875. PMID 10602382 DOI: 10.1038/Sj.Gt.3301026  0.593
1999 Tan Y, Li S, Pitt BR, Huang L. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Human Gene Therapy. 10: 2153-61. PMID 10498247 DOI: 10.1089/10430349950017149  0.426
1999 Li S, Tseng WC, Stolz DB, Wu SP, Watkins SC, Huang L. Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Therapy. 6: 585-594. PMID 10476218 DOI: 10.1038/Sj.Gt.3300865  0.414
1999 Kitson C, Angel B, Judd D, Rothery S, Severs NJ, Dewar A, Huang L, Wadsworth SC, Cheng SH, Geddes DM, Alton EW. The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium. Gene Therapy. 6: 534-46. PMID 10476213 DOI: 10.1038/Sj.Gt.3300840  0.321
1999 Savva M, Torchilin VP, Huang L. Effect of Grafted Amphiphilic PVP-Palmityl Polymers on the Thermotropic Phase Behavior of 1,2 Dipalmitoyl- sn-glycero-3-phosphocholine Bilayer. Journal of Colloid and Interface Science. 217: 166-171. PMID 10441425 DOI: 10.1006/Jcis.1999.6344  0.611
1999 Savva M, Torchilin VP, Huang L. Effect of Polyvinyl Pyrrolidone on the Thermal Phase Transition of 1,2 Dipalmitoyl-sn-glycero-3-phosphocholine Bilayer. Journal of Colloid and Interface Science. 217: 160-165. PMID 10441424 DOI: 10.1006/Jcis.1999.6343  0.607
1999 Brisson M, He Y, Li S, Yang JP, Huang L. A novel T7 RNA polymerase autogene for efficient cytoplasmic expression of target genes Gene Therapy. 6: 263-270. PMID 10435111 DOI: 10.1038/Sj.Gt.3300827  0.371
1999 Savva M, Duda E, Huang L. A genetically modified recombinant tumor necrosis factor-α conjugated to the distal terminals of liposomal surface grafted polyethyleneglycol chains International Journal of Pharmaceutics. 184: 45-51. PMID 10425350 DOI: 10.1016/S0378-5173(99)00092-7  0.65
1999 Li S, Wu SP, Whitmore M, Loeffert EJ, Wang L, Watkins SC, Pitt BR, Huang L. Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. The American Journal of Physiology. 276: L796-804. PMID 10330036 DOI: 10.1152/Ajplung.1999.276.5.L796  0.37
1999 Huang L. LPD nanoparticles for gene delivery Nature Biotechnology. 17: 18. DOI: 10.1038/70136  0.31
1998 Xing X, Zhang S, Chang JY, Tucker SD, Chen H, Huang L, Hung MC. Safety study and characterization of E1A-liposome complex gene-delivery protocol in an ovarian cancer model Gene Therapy. 5: 1538-1544. PMID 9930307 DOI: 10.1038/Sj.Gt.3300771  0.368
1998 He YK, Lui VW, Baar J, Wang L, Shurin M, Almonte C, Watkins SC, Huang L. Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor. Gene Therapy. 5: 1462-71. PMID 9930299 DOI: 10.1038/Sj.Gt.3300769  0.395
1998 Li S, Rizzo MA, Bhattacharya S, Huang L. Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery Gene Therapy. 5: 930-937. PMID 9813664 DOI: 10.1038/Sj.Gt.3300683  0.44
1998 Stern M, Sorgi F, Hughes C, Caplen NJ, Browning JE, Middleton PG, Gruenert DC, Farr SJ, Huang L, Geddes DM, Alton EW. The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro. Gene Therapy. 5: 583-93. PMID 9797862 DOI: 10.1038/Sj.Gt.3300629  0.338
1998 Li S, Deshmukh HM, Huang L. Folate-mediated targeting of antisense oligodeoxynucleotides to ovarian cancer cells. Pharmaceutical Research. 15: 1540-5. PMID 9794495 DOI: 10.1023/A:1011946915209  0.434
1998 Stern M, Caplen NJ, Browning JE, Griesenbach U, Sorgi F, Huang L, Gruenert DC, Marriot C, Crystal RG, Geddes DM, Alton EW. The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro. Gene Therapy. 5: 91-8. PMID 9536269 DOI: 10.1038/Sj.Gt.3300556  0.325
1998 Hara T, Tan Y, Huang L. In vivo gene delivery to the liver using reconstituted chylomicron remnants as a novel nonviral vector. Proceedings of the National Academy of Sciences of the United States of America. 94: 14547-52. PMID 9405650 DOI: 10.1073/Pnas.94.26.14547  0.324
1998 Li S, Huang L. Targeted Delivery of Antisense Oligodeoxynucleotides Formulated in a Novel Lipidic Vector Journal of Liposome Research. 8: 239-250. DOI: 10.3109/08982109809035529  0.42
1998 Brisson M, Huang L. Improved gene delivery formulations and expression systems for enhanced transaction efficiency Pure and Applied Chemistry. 70: 83-88. DOI: 10.1351/Pac199870010083  0.342
1998 Tseng W, Huang L. Liposome-based gene therapy Pharmaceutical Science & Technology Today. 1: 206-213. DOI: 10.1016/S1461-5347(98)00054-6  0.363
1997 Son K, Sorgi F, Gao X, Huang L. Cationic liposome-mediated gene transfer to tumor cells in vitro and in vivo. Methods in Molecular Medicine. 7: 329-337. PMID 24493437 DOI: 10.1385/0-89603-484-4:329  0.788
1997 Sorgi F, Bhattacharya S, Huang L. Protamine sulfate enhances lipid-mediated gene transfer Gene Therapy. 4: 961-968. PMID 9349433 DOI: 10.1038/Sj.Gt.3300484  0.343
1997 Li S, Huang L. In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes Gene Therapy. 4: 891-900. PMID 9349425 DOI: 10.1038/Sj.Gt.3300482  0.551
1997 Hui K, Ang P, Huang L, Tay S. Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes. Gene Therapy. 4: 783-790. PMID 9338006 DOI: 10.1038/Sj.Gt.3300455  0.344
1997 Li S, Brisson M, He Y, Huang L. Delivery of a PCR amplified DNA fragment into cells: A model for using synthetic genes for gene therapy Gene Therapy. 4: 449-454. PMID 9274722 DOI: 10.1038/Sj.Gt.3300413  0.411
1997 Liu F, Qi H, Huang L, Liu D. Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration. Gene Therapy. 4: 517-23. PMID 9231067 DOI: 10.1038/Sj.Gt.3300424  0.34
1997 Huang L, Li S. Liposomal gene delivery: a complex package. Nature Biotechnology. 15: 620-1. PMID 9219259 DOI: 10.1038/Nbt0797-620  0.4
1997 Xing X, Liu V, Xia W, Stephens LC, Huang L, Lopez-Berestein G, Hung MC. Safety studies of the intraperitoneal injection of E1A--liposome complex in mice. Gene Therapy. 4: 238-43. PMID 9135737 DOI: 10.1038/Sj.Gt.3300376  0.369
1997 Chang JY, Xia W, Shao R, Sorgi F, Hortobagyi GN, Huang L, Hung MC. The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer. Oncogene. 14: 561-8. PMID 9053854 DOI: 10.1038/Sj.Onc.1200861  0.8
1997 Liu F, Yang J, Huang L, Liu D. New cationic lipid formulations for gene transfer. Pharmaceutical Research. 13: 1856-60. PMID 8987084 DOI: 10.1023/A:1016041326636  0.318
1997 Li S, Huang L. Protamine Sulfate Provides Enhanced and Reproducible Intravenous Gene Transfer by Cationic Liposome/DNA Complex Journal of Liposome Research. 7: 207-219. DOI: 10.3109/08982109709035496  0.422
1997 Huang L, Li S. Intravenous Delivery of Genes: Introduction to the Forum Journal of Liposome Research. 7: vii-xi. DOI: 10.3109/08982109709035491  0.403
1997 Li S, Huang L. Targeted Delivery of Antisense Oligodeoxynucleotides by LPDII Journal of Liposome Research. 7: 63-75. DOI: 10.3109/08982109709035482  0.432
1997 Huang L. Liposomal Oligonucleotides: Forum Introduction Journal of Liposome Research. 7. DOI: 10.3109/08982109709035477  0.321
1997 Lee RJ, Huang L. Lipidic vector systems for gene transfer. Critical Reviews in Therapeutic Drug Carrier Systems. 14: 173-206. DOI: 10.1615/Critrevtherdrugcarriersyst.V14.I2.30  0.34
1997 Hara T, Liu F, Liu D, Huang L. Emulsion formulations as a vector for gene delivery in vitro and in vivo Advanced Drug Delivery Reviews. 24: 265-271. DOI: 10.1016/S0169-409X(96)00467-X  0.381
1997 Sorgi FL, Huang L. Chapter 12 Drug Delivery Applications Current Topics in Membranes. 44: 449-475. DOI: 10.1016/S0070-2161(08)60216-6  0.783
1996 Liu F, Yang J, Huang L, Liu D. Effect of non-ionic surfactants on the formation of DNA/emulsion complexes and emulsion-mediated gene transfer. Pharmaceutical Research. 13: 1642-1646. PMID 8956328 DOI: 10.1023/A:1016480421204  0.304
1996 Bedu-Addo FK, Huang L. Effect of Matrix Lipid Chain Length on Liposomes Containing Cholesterol and Ganglioside GM1: Implications in Drug Delivery Journal of Pharmaceutical Sciences. 85: 714-719. PMID 8818995 DOI: 10.1021/Js950518E  0.307
1996 Buiting AMJ, Zhou F, Bakker JAJ, Rooijen Nv, Huang L. Biodistribution of clodronate and liposomes used in the liposome mediated macrophage ‘suicide’ approach Journal of Immunological Methods. 192: 55-62. PMID 8699022 DOI: 10.1016/0022-1759(96)00034-8  0.32
1996 Lee RJ, Huang L. Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer Journal of Biological Chemistry. 271: 8481-8487. PMID 8626549 DOI: 10.1074/Jbc.271.14.8481  0.352
1996 Mori A, Wu SP, Han I, Khokhar AR, Perez-Soler R, Huang L. In vivo antitumor activity of cis-bis-neodecanoato-trans-R,R-1, 2-diaminocyclohexane platinum(II) formulated in long-circulating liposomes. Cancer Chemotherapy and Pharmacology. 37: 435-444. PMID 8599866 DOI: 10.1007/S002800050409  0.399
1996 Huang L, Farhood H, Serbina N, Teepe AG, Barsoum J. Endosomolytic activity of cationic liposomes enhances the delivery of human immunodeficiency virus-1 trans-activator protein (TAT) to mammalian cells. Biochemical and Biophysical Research Communications. 217: 761-8. PMID 8554596 DOI: 10.1006/Bbrc.1995.2838  0.348
1996 Gao X, Huang L. Potentiation of Cationic Liposome-Mediated Gene Delivery by Polycations† Biochemistry. 35: 1027-1036. PMID 8547238 DOI: 10.1021/Bi952436A  0.329
1996 Zhou F, Huang L. Delivery of protein antigen to the major histocompatibility complex class I-restricted antigen presentation pathway. Journal of Drug Targeting. 3: 91-109. PMID 7496732 DOI: 10.3109/10611869509059210  0.318
1996 Li S, Huang L. Lipidic Supramolecular Assemblies for Gene Transfer Journal of Liposome Research. 6: 589-608. DOI: 10.3109/08982109609031138  0.402
1996 Sorgi FL, Huang L. Large scale production of DC-Chol cationic liposomes by microfluidization International Journal of Pharmaceutics. 144: 131-139. DOI: 10.1016/S0378-5173(96)04733-3  0.774
1996 Mori A, Duda E, Huang L. Recombinant human tumor necrosis factor-α covalently conjugated to long-circulating liposomes International Journal of Pharmaceutics. 131: 57-66. DOI: 10.1016/0378-5173(95)04304-7  0.36
1996 Li S, Gao X, Son K, Sorgi F, Hofland H, Huang L. DC-Chol lipid system in gene transfer Journal of Controlled Release. 39: 373-381. DOI: 10.1016/0168-3659(95)00167-0  0.802
1995 Mori A, Kennel SJ, van Borssum Waalkes M, Scherphof GL, Huang L. Characterization of organ-specific immunoliposomes for delivery of 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine in a mouse lung-metastasis model. Cancer Chemotherapy and Pharmacology. 35: 447-56. PMID 7882453 DOI: 10.1007/Bf00686828  0.336
1995 Hofland H, Huang L. Inhibition of human ovarian carcinoma cell proliferation by liposome-plasmid DNA complex. Biochemical and Biophysical Research Communications. 207: 492-496. PMID 7864835 DOI: 10.1006/Bbrc.1995.1215  0.346
1995 Zhou F, Huang L. Liposome-mediated cytoplasmic delivery of proteins: an effective means of accessing the MHC class I-restricted antigen presentation pathway. Immunomethods. 4: 229-35. PMID 7820454 DOI: 10.1006/Immu.1994.1025  0.308
1995 Farhood H, Gao X, Barsoum J, Huang L. Codelivery to mammalian cells of a transcriptional factor with cis-acting element using cationic liposomes. Analytical Biochemistry. 225: 89-93. PMID 7778790 DOI: 10.1006/Abio.1995.1112  0.31
1995 Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochimica Et Biophysica Acta. 1235: 289-95. PMID 7756337 DOI: 10.1016/0005-2736(95)80016-9  0.35
1995 Hung MC, Matin A, Zhang Y, Xing X, Sorgi F, Huang L, Yu D. HER-2/neu-targeting gene therapy--a review. Gene. 159: 65-71. PMID 7607574 DOI: 10.1016/0378-1119(94)00459-6  0.805
1995 Goyal K, Huang L. Gene Therapy Using Dc-Chol Liposomes Journal of Liposome Research. 5: 49-60. DOI: 10.3109/08982109509039907  0.362
1995 Mori A, Huang L. Targeted Immunoliposomes: Potential Role in the Delivery of Cytotoxic Drugs Clinical Immunotherapeutics. 3: 227-240. DOI: 10.1007/Bf03259058  0.31
1994 Hui KM, Sabapathy TK, Oei AA, Singhal A, Huang L. Induction of alloreactive cytotoxic T lymphocytes by intra-splenic immunization with allogeneic class I Major Histocompatibility Complex DNA and DC-chol cationic liposomes. Journal of Liposome Research. 4: 1075-1090. PMID 29052490 DOI: 10.3109/08982109409018623  0.406
1994 Zhou X, Huang L. DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochimica Et Biophysica Acta. 1189: 195-203. PMID 8292625 DOI: 10.1016/0005-2736(94)90066-3  0.325
1994 Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proceedings of the National Academy of Sciences of the United States of America. 90: 11307-11. PMID 8248244 DOI: 10.1073/Pnas.90.23.11307  0.348
1994 Litzinger DC, Buiting AMJ, Rooijen Nv, Huang L. Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes Biochimica Et Biophysica Acta. 1190: 99-107. PMID 8110825 DOI: 10.1016/0005-2736(94)90038-8  0.374
1994 Farhood H, Gao X, Son K, Lazo JS, Huang L, Barsoum J, Bottega R, Epand RM. Cationic liposomes for direct gene transfer in therapy of cancer and other diseases. Annals of the New York Academy of Sciences. 716: 23-35. PMID 8024197 DOI: 10.1111/J.1749-6632.1994.Tb21701.X  0.384
1994 Son K, Huang L. Exposure of human ovarian carcinoma to cisplatin transiently sensitizes the tumor cells for liposome-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 91: 12669-12672. PMID 7809098 DOI: 10.1073/Pnas.91.26.12669  0.4
1994 Sternberg B, Sorgi FL, Huang L. New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy. Febs Letters. 356: 361-366. PMID 7805873 DOI: 10.1016/0014-5793(94)01315-2  0.768
1994 Singhal A, Huang L. Direct gene transfer by liposomes Journal of Liposome Research. 4: 289-299. DOI: 10.3109/08982109409037044  0.336
1994 Liu D, Huang L. Interaction of pH-Sensitive Liposomes With Blood Components Journal of Liposome Research. 4: 121-141. DOI: 10.3109/08982109409037033  0.305
1993 Plautz GE, Yang ZY, Wu BY, Gao X, Huang L, Nabel GJ. Immunotherapy of malignancy by in vivo gene transfer into tumors. Proceedings of the National Academy of Sciences of the United States of America. 90: 4645-9. PMID 8506311 DOI: 10.1089/Hum.1992.3.4-399  0.387
1993 Mori A, Kennel SJ, Huang L. Immunotargeting of liposomes containing lipophilic antitumor prodrugs. Pharmaceutical Research. 10: 507-14. PMID 8483832 DOI: 10.1023/A:1018933632318  0.376
1993 Zhou F, Huang L. Monophosphoryl lipid A enhances specific CTL induction by a soluble protein antigen entrapped in liposomes Vaccine. 11: 1139-1144. PMID 8249434 DOI: 10.1016/0264-410X(93)90076-A  0.34
1993 Nabel EG, Gordon D, Yang ZY, Xu L, San H, Plautz GE, Wu BY, Gao X, Huang L, Nabel GJ. Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization. Human Gene Therapy. 3: 649-56. PMID 1482705 DOI: 10.1089/Hum.1992.3.6-649  0.333
1993 Huang L, Klibanov AL, Mori A, Gao X. Targeted Delivery of Drugs and DNA with Liposomes Journal of Liposome Research. 3: 505-515. DOI: 10.3109/08982109309150733  0.315
1993 Gao X, Huang L. Cationic Liposomes and Polymers for Gene Transfer Journal of Liposome Research. 3: 17-30. DOI: 10.3109/08982109309147441  0.369
1992 Stewart MJ, Plautz GE, Del Buono L, Yang ZY, Xu L, Gao X, Huang L, Nabel EG, Nabel GJ. Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice. Human Gene Therapy. 3: 267-75. PMID 1643147 DOI: 10.1089/Hum.1992.3.3-267  0.332
1992 Litzinger DC, Huang L. Amphipathic poly(ethylene glycol) 5000-stabilized dioleoylphosphatidylethanolamine liposomes accumulate in spleen Biochimica Et Biophysica Acta. 1127: 249-254. PMID 1511002 DOI: 10.1016/0005-2760(92)90228-N  0.302
1992 Pinnaduwage P, Huang L. Stable target-sensitive immunoliposomes. Biochemistry. 31: 2850-2855. PMID 1372514 DOI: 10.1021/Bi00126A002  0.305
1992 Kiibanov AL, Huang L. Long-Circulating Liposomes: Development and Perspectives Journal of Liposome Research. 2: 321-334. DOI: 10.3109/08982109209010212  0.308
1991 Gao X, Huang L. A novel cationic liposome reagent for efficient transfection of mammalian cells Biochemical and Biophysical Research Communications. 179: 280-285. PMID 1883357 DOI: 10.1016/0006-291X(91)91366-K  0.305
1990 Klibanov AL, Maruyama K, Torchilin VP, Huang L. Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. Febs Letters. 268: 235-7. PMID 2384160 DOI: 10.1016/0014-5793(90)81016-H  0.328
1974 Huang L, Jaquet DD, Haug A. Effect of fatty acyl chain length on some structural and functional parameters of Acholeplasma membranes. Canadian Journal of Biochemistry. 52: 483-90. PMID 4844283 DOI: 10.1139/O74-072  0.502
1974 Hsung JC, Huang L, Hoy DJ, Haug A. Lipid and temperature dependence of membrane-bound ATPase activity of Acholeplasma laidlawii. Canadian Journal of Biochemistry. 52: 974-80. PMID 4371925 DOI: 10.1139/O74-136  0.492
1974 Huang L, Lorch SK, Smith GG, Haug A. Control of membrane lipid fluidity in Acholeplasma laidlawii. Febs Letters. 43: 1-5. PMID 4368536 DOI: 10.1016/0014-5793(74)81090-2  0.494
1974 Huang L, Haug A. Regulation of membrane lipid fluidity in Acholeplasma laidlawii: Effect of carotenoid pigment content Bba - Biomembranes. 352: 361-370. PMID 4366832 DOI: 10.1016/0005-2736(74)90228-4  0.514
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