Yunching Chen, Ph.D. - Publications

Affiliations: 
2010 Pharmaceutical Sciences University of North Carolina, Chapel Hill, Chapel Hill, NC 

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Year Citation  Score
2023 Mu HY, Lin CM, Chu LA, Lin YH, Li J, Yu Liu C, Huang HC, Cheng SL, Lee TY, Lee HM, Chen HM, Tsai YJ, Chen Y, Huang JH. Ex Vivo Evaluation of Combination Immunotherapy Using Tumor-Microenvironment-on-Chip. Advanced Healthcare Materials. e2302268. PMID 37748773 DOI: 10.1002/adhm.202302268  0.559
2023 Lee TY, Lu HH, Cheng HT, Huang HC, Tsai YJ, Chang IH, Tu CP, Chung CW, Lu TT, Peng CH, Chen Y. Delivery of nitric oxide with a pH-responsive nanocarrier for the treatment of renal fibrosis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 354: 417-428. PMID 36627025 DOI: 10.1016/j.jconrel.2022.12.059  0.711
2023 Magoling BJA, Wu AY, Chen YJ, Wong WW, Chuo ST, Huang HC, Sung YC, Hsieh HT, Huang P, Lee KZ, Huang KW, Chen RH, Chen Y, Lai CP. Membrane Protein Modification Modulates Big and Small Extracellular Vesicle Biodistribution and Tumorigenic Potential in Breast Cancers in vivo. Advanced Materials (Deerfield Beach, Fla.). e2208966. PMID 36609913 DOI: 10.1002/adma.202208966  0.783
2022 Hsieh HT, Huang HC, Chung CW, Chiang CC, Hsia T, Wu HF, Huang RL, Chiang CS, Wang J, Lu TT, Chen Y. CXCR4-targeted nitric oxide nanoparticles deliver PD-L1 siRNA for immunotherapy against glioblastoma. Journal of Controlled Release : Official Journal of the Controlled Release Society. 352: 920-930. PMID 36334859 DOI: 10.1016/j.jconrel.2022.10.047  0.81
2022 Hsiao SK, Liang CW, Chang TL, Sung YC, Chen YT, Chen Y, Wang J. An fibrotic liver lobule model through sequential cell-seeding of HSCs and HepG2 on 3D-printed poly(glycerol sebacate) acrylate scaffolds. Journal of Materials Chemistry. B. PMID 36106522 DOI: 10.1039/d1tb02686k  0.577
2022 Chen HY, Chan SJ, Liu X, Wei AC, Jian RI, Huang KW, Lang YD, Shih JH, Liao CC, Luan CL, Kao YT, Chiang SY, Hsiao PW, Jou YS, Chen Y, et al. Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression. Journal of Hematology & Oncology. 15: 85. PMID 35794621 DOI: 10.1186/s13045-022-01306-3  0.729
2022 Cheng HT, Huang HC, Lee TY, Liao YH, Sheng YH, Jin PR, Huang KW, Chen LH, Chen YT, Liu ZY, Lin TC, Wang HC, Chao CH, Juang IP, Su CT, ... ... Chen Y, et al. Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 346: 169-179. PMID 35429575 DOI: 10.1016/j.jconrel.2022.04.004  0.778
2022 Hong YH, Narwane M, Liu LY, Huang YD, Chung CW, Chen YH, Liao BW, Chang YH, Wu CR, Huang HC, Hsu IJ, Cheng LY, Wu LY, Chueh YL, Chen Y, et al. Enhanced Oral NO Delivery through Bioinorganic Engineering of Acid-Sensitive Prodrug into a Transformer-like DNIC@MOF Microrod. Acs Applied Materials & Interfaces. PMID 35019259 DOI: 10.1021/acsami.1c21409  0.458
2021 Huang HC, Sung YC, Li CP, Wan D, Chao PH, Tseng YT, Liao BW, Cheng HT, Hsu FF, Huang CC, Chen YT, Liao YH, Hsieh HT, Shih YC, Liu IJ, ... ... Chen Y, et al. Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours. Gut. PMID 34921062 DOI: 10.1136/gutjnl-2021-325180  0.775
2021 Jin PR, Ta YN, Chen IT, Yu YN, Hsieh HT, Nguyen VT, Hsieh SY, Hsia T, Liu H, Hsu CW, Han JL, Chen Y. Cinchona Alkaloid-Inspired Urea-Containing Autophagy Inhibitor Shows Single-Agent Anticancer Efficacy. Journal of Medicinal Chemistry. PMID 34558909 DOI: 10.1021/acs.jmedchem.1c01036  0.83
2021 Wu CR, Huang YD, Hong YH, Liu YH, Narwane M, Chang YH, Dinh TK, Hsieh HT, Hseuh YJ, Wu PC, Pao CW, Chan TS, Hsu IJ, Chen Y, Chen HC, et al. Endogenous Conjugation of Biomimetic Dinitrosyl Iron Complex with Protein Vehicles for Oral Delivery of Nitric Oxide to Brain and Activation of Hippocampal Neurogenesis. Jacs Au. 1: 998-1013. PMID 34467346 DOI: 10.1021/jacsau.1c00160  0.768
2021 Song JS, Chang CC, Wu CH, Dinh TK, Jan JJ, Huang KW, Chou MC, Shiue TY, Yeh KC, Ke YY, Yeh TK, Ta YN, Lee CJ, Huang JK, Sung YC, ... ... Chen Y, et al. A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33753481 DOI: 10.1073/pnas.2015433118  0.812
2020 Wu AY, Sung YC, Chen YJ, Chou ST, Guo V, Chien JC, Ko JJ, Yang AL, Huang HC, Chuang JC, Wu S, Ho MR, Ericsson M, Lin WW, Cheung CHY, ... ... Chen Y, et al. Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2001467. PMID 33042758 DOI: 10.1002/Advs.202001467  0.773
2020 Chang CC, Dinh TK, Lee YA, Wang FN, Sung YC, Yu PL, Chiu SC, Shih YC, Wu CY, Huang YD, Wang J, Lu TT, Wan D, Chen Y. Nanoparticle Delivery of MnO2 and Anti-angiogenic Therapy to Overcome Hypoxia-Driven Tumor Escape and Suppress Hepatocellular Carcinoma. Acs Applied Materials & Interfaces. PMID 32865389 DOI: 10.1021/Acsami.0C08473  0.806
2020 Huang KW, Hsu FF, Qiu JT, Chern GJ, Lee YA, Chang CC, Huang YT, Sung YC, Chiang CC, Huang RL, Lin CC, Dinh TK, Huang HC, Shih YC, Alson D, ... ... Chen Y, et al. Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer. Science Advances. 6: eaax5032. PMID 31998834 DOI: 10.1126/Sciadv.Aax5032  0.748
2019 Sung YC, Jin PR, Chu LA, Hsu FF, Wang MR, Chang CC, Chiou SJ, Qiu JT, Gao DY, Lin CC, Chen YS, Hsu YC, Wang J, Wang FN, Yu PL, ... ... Chen Y, et al. Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies. Nature Nanotechnology. PMID 31740794 DOI: 10.1038/S41565-019-0570-3  0.778
2019 Lin CH, Wen HC, Chiang CC, Huang JS, Chen Y, Wang SK. Polyproline Tri-Helix Macrocycles as Nanosized Scaffolds to Control Ligand Patterns for Selective Protein Oligomer Interactions. Small (Weinheim An Der Bergstrasse, Germany). e1900561. PMID 30977296 DOI: 10.1002/Smll.201900561  0.758
2018 Huang KW, Lai YT, Chern GJ, Huang SF, Tsai CL, Sung YC, Chiang CC, Hwang PB, Ho TL, Huang RL, Shiue TY, Chen Y, Wang SK. Galactose Derivative-Modified Nanoparticles for Efficient siRNA Delivery to Hepatocellular Carcinoma. Biomacromolecules. PMID 29808997 DOI: 10.1021/Acs.Biomac.8B00358  0.799
2018 Sung YC, Liu YC, Chao PH, Chang CC, Jin PR, Lin TT, Lin JA, Cheng HT, Wang J, Lai CP, Chen LH, Wu AY, Ho TL, Chiang T, Gao DY, ... ... Chen Y, et al. Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development. Theranostics. 8: 894-905. PMID 29463989 DOI: 10.7150/Thno.21168  0.784
2017 Chih-Chun C, Yang Y, Gao DY, Cheng HT, Hoang B, Chao PH, Chen LH, Bteich J, Chiang T, Liu JY, Li SD, Chen Y. Docetaxel-carboxymethylcellulose nanoparticles ameliorate CCl4-induced hepatic fibrosis in Mice. Journal of Drug Targeting. 1-27. PMID 29251522 DOI: 10.1080/1061186X.2017.1419358  0.806
2017 Liu CH, Chern GG, Hsu FF, Huang KW, Sung YC, Huang HC, Qiu JT, Wang SK, Lin CC, Wu CH, Wu HC, Liu JY, Chen Y. A multifunctional nanocarrier for efficient TRAIL-based gene therapy against hepatocellular carcinoma with desmoplasia. Hepatology (Baltimore, Md.). PMID 28885731 DOI: 10.1002/Hep.29513  0.807
2017 Chen Y, Liu YC, Sung YC, Ramjiawan RR, Lin TT, Chang CC, Jeng KS, Chang CF, Liu CH, Gao DY, Hsu FF, Duyverman AM, Kitahara S, Huang P, Dima S, et al. Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors. Scientific Reports. 7: 44123. PMID 28276530 DOI: 10.1038/Srep44123  0.824
2017 Wang L, Chen Y, Lin HY, Hou YT, Yang LC, Sun AY, Liu JY, Chang CW, Wan D. Near-IR-Absorbing Gold Nanoframes with Enhanced Physiological Stability and Improved Biocompatibility for In Vivo Biomedical Applications. Acs Applied Materials & Interfaces. PMID 28071899 DOI: 10.1021/Acsami.6B12591  0.347
2016 Wang B, Liu Y, Huang L, Chen J, Li JJ, Wang R, Kim E, Chen Y, Justicia C, Sakata K, Chen H, Planas A, Ostrom RS, Li W, Yang G, et al. A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism. Molecular Psychiatry. PMID 27457810 DOI: 10.1038/Mp.2016.104  0.35
2016 Chen CW, Tsao N, Huang LY, Yen Y, Liu X, Lehman C, Wang YH, Tseng MC, Chen YJ, Ho YC, Chen CF, Chang ZF. The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells. Cell Reports. PMID 27452458 DOI: 10.1016/j.celrep.2016.06.094  0.347
2016 Zhang Z, Li Y, Huang L, Xiao Q, Chen X, Zhong J, Chen Y, Yang D, Han Z, Shu Y, Dai M, Cao K. Corrigendum to 'Let-7a suppresses macrophage infiltrations and malignant phenotype of Ewing sarcoma via STAT3/NF-κB positive regulatory circuit' [Cancer Lett. 374 (2016) 192-201]. Cancer Letters. PMID 27448532 DOI: 10.1016/j.canlet.2016.07.010  0.345
2016 Sheen JM, Chen YC, Hsu MH, Tain YL, Yu HR, Huang LT. Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation. Frontiers in Cellular Neuroscience. 10: 167. PMID 27445694 DOI: 10.3389/Fncel.2016.00167  0.36
2016 Chen Y, Lu Z, Zhao J, Zou Z, Gong Y, Qu F, Bao Z, Qiu G, Song M, Zhang Q, Liu L, Hu M, Han X, Tian S, Zhao J, et al. Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus from China. Antimicrobial Agents and Chemotherapy. PMID 27431231 DOI: 10.1128/AAC.01005-16  0.308
2016 Huang L, Chen YT, Li YX, Yu LS. Application of Chiral Ionic Liquid-Modified Gold Nanoparticles in the Chiral Recognition of Amino Acid Enantiomers. Applied Spectroscopy. PMID 27418633 DOI: 10.1177/0003702816645353  0.35
2016 Liang XE, Zhong C, Huang L, Yang S, Zhu Y, Chen Y, Hou J. Stepwise Application of Transient Elastography and Routine Biomarkers Optimizes Hepatitis B Cirrhosis Detection. Journal of Gastroenterology and Hepatology. PMID 27346683 DOI: 10.1111/jgh.13475  0.388
2016 Hou J, Huang L, Yang Z, Zhao Y, Deng C, Chen Y, Li X. Adsorption of ammonium on biochar prepared from giant reed. Environmental Science and Pollution Research International. PMID 27344654 DOI: 10.1007/s11356-016-7084-4  0.301
2016 Chu Y, Zhu Y, Chen Y, Li W, Zhang Z, Liu D, Wang T, Ma J, Deng H, Liu ZJ, Ouyang S, Huang L. aKMT catalyzes extensive protein lysine methylation in the hyperthermophilic archaeon Sulfolobus islandicus but is dispensable for the growth of the organism. Molecular & Cellular Proteomics : McP. PMID 27329856 DOI: 10.1074/mcp.M115.057778  0.321
2016 Feng SW, Chen Y, Tsai WC, Chiou HC, Wu ST, Huang LC, Lin C, Hsieh CC, Yang YJ, Hueng DY. Overexpression of TELO2 decreases survival in human high-grade gliomas. Oncotarget. PMID 27329594 DOI: 10.18632/oncotarget.10021  0.349
2016 Huang L, Liu S, Lei Y, Wang K, Xu M, Chen Y, Liu B, Chen Y, Fu Q, Zhang P, Qin K, Cai Y, Fu S, Ge S, Yuan X. Systemic immune-inflammation index, thymidine phosphorylase and survival of localized gastric cancer patients after curative resection. Oncotarget. PMID 27283904 DOI: 10.18632/oncotarget.9923  0.383
2016 Huang L, Wu B, Zhao J, Li H, Chen W, Zheng Y, Ren X, Chen Y, Zhou X, Lei Y, Liao B, Jiang H. Characterization and Transferable Utility of Microsatellite Markers in the Wild and Cultivated Arachis Species. Plos One. 11: e0156633. PMID 27243460 DOI: 10.1371/journal.pone.0156633  0.311
2016 Liu CH, Chan KM, Chiang T, Liu JY, Chern GG, Hsu FF, Wu YH, Liu YC, Chen Y. Dual-functional nanoparticles targeting CXCR4 and delivering anti-angiogenic siRNA ameliorate liver fibrosis. Molecular Pharmaceutics. PMID 27224003 DOI: 10.1021/Acs.Molpharmaceut.5B00913  0.701
2016 Chen Y, Li C, Liu L, Guo F, Li S, Huang L, Sun C, Feng R. Serum metabonomics of NAFLD plus T2DM based on liquid chromatography-mass spectrometry. Clinical Biochemistry. PMID 27211699 DOI: 10.1016/j.clinbiochem.2016.05.016  0.339
2016 Chen YS, Li HR, Zhang W, Hua ZD, Lin XH, Lin MQ, Huang WS, Huang LP, Yu XL, Xu NL, Lin M, Xie BS, Shen XN, Xie JF, Wang Y, et al. Development of a bead-based suspension array for the detection of pathogens in acute respiratory tract infections. Experimental Biology and Medicine (Maywood, N.J.). PMID 27190247 DOI: 10.1177/1535370216647128  0.323
2016 Huang LY, Wang YC, Wu CC, Chen YC, Huang YL. Risk of Flood-Related Diseases of Eyes, Skin and Gastrointestinal Tract in Taiwan: A Retrospective Cohort Study. Plos One. 11: e0155166. PMID 27171415 DOI: 10.1371/journal.pone.0155166  0.305
2016 Huang L, Chen L, Huang P, Wu F, Tan L, Xiao S, Zhong W, Sun L, Chen Y. Triple Dipole Effect from Self-Assembled Small-Molecules for High Performance Organic Photovoltaics. Advanced Materials (Deerfield Beach, Fla.). PMID 27115312 DOI: 10.1002/adma.201600197  0.3
2016 Zhang HH, Lechuga TJ, Chen Y, Yang Y, Huang L, Chen DB. Quantitative Proteomics Analysis of VEGF-responsive Endothelial Protein S-Nitrosylation Using Stable Isotope Labeling of Amino Acids in Cell Culture (SILAC) and LC-MS/MS. Biology of Reproduction. PMID 27075618 DOI: 10.1095/biolreprod.116.139337  0.341
2016 Sheen JM, Hsieh CS, Tain YL, Li SW, Yu HR, Chen CC, Tiao MM, Chen YC, Huang LT. Programming Effects of Prenatal Glucocorticoid Exposure with a Postnatal High-Fat Diet in Diabetes Mellitus. International Journal of Molecular Sciences. 17. PMID 27070590 DOI: 10.3390/ijms17040533  0.314
2016 Wong TY, Chen YH, Liu SH, Solis MA, Yu CH, Chang CH, Huang LL. Differential Proteomic Analysis of Human Placenta-Derived Mesenchymal Stem Cells Cultured on Normal Tissue Culture Surface and Hyaluronan-Coated Surface. Stem Cells International. 2016: 2809192. PMID 27057169 DOI: 10.1155/2016/2809192  0.35
2016 Chen YH, Huang L, Wen ZH, Zhang C, Liang CH, Lai ST, Luo LZ, Wang YY, Wang GH. Skin whitening capability of shikimic acid pathway compound. European Review For Medical and Pharmacological Sciences. 20: 1214-1220. PMID 27049279  0.316
2016 Chen YD, Jin XQ, Yu MH, Fang Y, Huang LQ. Acupuncture for moderate to severe allergic rhinitis: A non-randomized controlled trial. Chinese Journal of Integrative Medicine. PMID 27048410 DOI: 10.1007/s11655-016-2453-x  0.324
2016 Chen YW, Guo JY, Tzeng SY, Chou TC, Lin MJ, Huang LL, Yang CC, Hsu CK, Tseng SH. Toward reliable retrieval of functional information of papillary dermis using spatially resolved diffuse reflectance spectroscopy. Biomedical Optics Express. 7: 542-58. PMID 26977361 DOI: 10.1364/BOE.7.000542  0.303
2016 Lin CJ, Kuan CH, Wang LW, Wu HC, Chen Y, Chang CW, Huang RY, Wang TW. Integrated self-assembling drug delivery system possessing dual responsive and active targeting for orthotopic ovarian cancer theranostics. Biomaterials. 90: 12-26. PMID 26974704 DOI: 10.1016/J.Biomaterials.2016.03.005  0.41
2016 Chen Y, Anwar P, Huang L, Asvial M. Characterizing Nanoscale Transient Communication. Ieee Transactions On Nanobioscience. PMID 26955048 DOI: 10.1109/TNB.2016.2536645  0.308
2016 Fan Z, Wen T, Chen Y, Huang L, Lin W, Yin C, Tan W. Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes. Oxidative Medicine and Cellular Longevity. 2016: 6362812. PMID 26949448 DOI: 10.1155/2016/6362812  0.337
2016 Zhang Z, Li Y, Huang L, Xiao Q, Chen X, Zhong J, Chen Y, Yang D, Han Z, Shu Y, Dai M, Cao K. Let-7a suppresses macrophage infiltrations and malignant phenotype of ewing sarcoma via STAT3/ NF-κB positive regulatory circuit. Cancer Letters. PMID 26902422 DOI: 10.1016/j.canlet.2016.02.027  0.402
2016 Wu L, Chen Y, Gao H, Yin J, Huang L. Cadmium-induced cell killing in Sacharomyces cerevisiae involves increases in intracellular NO levels. Fems Microbiology Letters. PMID 26872495 DOI: 10.1093/femsle/fnw032  0.364
2016 Huang L, Xi Z, Wang C, Zhang Y, Yang Z, Zhang S, Chen Y, Zuo Z. Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation. Scientific Reports. 6: 20105. PMID 26830171 DOI: 10.1038/srep20105  0.325
2016 Lin YC, Chen YF, Tseng LS, Lee YH, Morris-Natschke SL, Kuo SC, Yang NS, Lee KH, Huang LJ. Synthesis and structure-activity relationship studies of novel 3,9-substituted α-carboline derivatives with high cytotoxic activity against colorectal cancer cells. European Journal of Medicinal Chemistry. 110: 98-114. PMID 26820553 DOI: 10.1016/j.ejmech.2016.01.004  0.372
2016 Huang L, Shen C, Chen Y, Yan H, Cheng Z, Zhu Q. Simotinib as a modulator of P-glycoprotein: substrate, inhibitor, or inducer? Anti-Cancer Drugs. PMID 26766493 DOI: 10.1097/CAD.0000000000000332  0.347
2016 Chen Y, Huang L, Zhang H, Diao X, Zhao S, Zhou W. Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage. Molecular Neurobiology. PMID 26742518 DOI: 10.1007/s12035-015-9629-9  0.334
2016 Wei FJ, Tsai YC, Wu HP, Huang LT, Chen YC, Chen YF, Wu CC, Tseng YT, Hsing YI. Both Hd1 and Ehd1 are important for artificial selection of flowering time in cultivated rice. Plant Science : An International Journal of Experimental Plant Biology. 242: 187-94. PMID 26566836 DOI: 10.1016/j.plantsci.2015.09.005  0.328
2016 Chen Y, Liu Y, Lin T, Ramjiawan R, Duda D. Abstract 1315: Nanoparticles targeting RAF/ERK-driven cell-autonomous resistance to sorafenib for effective treatment of hepatocellular carcinoma Cancer Research. 76: 1315-1315. DOI: 10.1158/1538-7445.Am2016-1315  0.496
2016 Xu YF, Xu GL, Su H, Chen Y, Fang JC, Wang Q, Huang L, Li JT, Sun SG. Porous MnO/C of composite nanostructure consisting of nanorods and nano-octahedra as anode of lithium ion batteries with enhanced electrochemical performances Journal of Alloys and Compounds. 676: 156-163. DOI: 10.1016/J.Jallcom.2016.03.151  0.303
2015 Liu JY, Chiang T, Liu CH, Chern GG, Lin TT, Gao DY, Chen Y. Delivery of siRNA Using CXCR4-targeted Nanoparticles Modulates Tumor Microenvironment and Achieves a Potent Antitumor Response in Liver Cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1772-1782. PMID 28142020 DOI: 10.1038/mt.2015.147  0.464
2015 Sun Z, Luo B, Liu Z, Huang L, Liu B, Ma T, Gao B, Liu ZH, Chen YF, Huang JH, Luo Z. Effect of perfluorotributylamine-enriched alginate on nucleus pulposus cell: Implications for intervertebral disc regeneration. Biomaterials. 82: 34-47. PMID 26741882 DOI: 10.1016/j.biomaterials.2015.12.013  0.399
2015 Chen Z, Qian Y, Liu S, Huang L, Xu S, Yin W, Chen Y, Wu H, Wang G. [Onset time and efficacy of sublingual immunotherapy with Dermatophagoides farinae drops in children with allergic rhinitis]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 50: 622-6. PMID 26696197  0.315
2015 Zeng Q, Wang Q, Chen X, Xia K, Tang J, Zhou X, Cheng Y, Chen Y, Huang L, Xiang H, Cao K, Zhou J. Analysis of lncRNAs expression in UVB-induced stress responses of melanocytes. Journal of Dermatological Science. PMID 26596215 DOI: 10.1016/j.jdermsci.2015.10.019  0.318
2015 Huang L, Chen Y, Chen Y, Wu H. Centrifugation-assisted single-cell trapping (CAScT) in a truncated cone-shaped microwell array (TCMA) chip for the real-time observation of cellular apoptosis. Analytical Chemistry. PMID 26579559 DOI: 10.1021/Acs.Analchem.5B03031  0.355
2015 Lin TT, Gao DY, Liu YC, Sung YC, Wan D, Liu JY, Chiang T, Wang L, Chen Y. Development and characterization of sorafenib-loaded PLGA nanoparticles for the systemic treatment of liver fibrosis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26551344 DOI: 10.1016/J.Jconrel.2015.11.003  0.802
2015 Chang D, Gao Y, Wang L, Liu G, Chen Y, Wang T, Tao W, Mei L, Huang L, Zeng X. Polydopamine-based surface modification of mesoporous silica nanoparticles as pH-sensitive drug delivery vehicles for cancer therapy. Journal of Colloid and Interface Science. 463: 279-287. PMID 26550786 DOI: 10.1016/j.jcis.2015.11.001  0.41
2015 Chen Y, Li G, Huang LY. p38 MAPK mediates glial P2X7R-neuronal P2Y1R inhibitory control of P2X3R expression in dorsal root ganglion neurons. Molecular Pain. 11: 68. PMID 26542462 DOI: 10.1186/S12990-015-0073-7  0.336
2015 Chen Y, Sun J, Huang LC, Xu H, Zhao Z. Classification of Cancer Primary Sites Using Machine Learning and Somatic Mutations. Biomed Research International. 2015: 491502. PMID 26539502 DOI: 10.1155/2015/491502  0.365
2015 Wang Y, Cai J, Zeng X, Chen Y, Yan W, Ouyang Y, Xiao D, Zeng Z, Huang L, Liu A. Downregulation of toll-like receptor 4 induces suppressive effects on hepatitis B virus-related hepatocellular carcinoma via ERK1/2 signaling. Bmc Cancer. 15: 821. PMID 26514586 DOI: 10.1186/s12885-015-1866-9  0.484
2015 Wang F, Chen Y, Huang L, Liu T, Huang Y, Zhao J, Wang X, Yang K, Ma S, Huang L, To KK, Gu Y, Fu L. Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/P-glycoprotein-overexpressing cancer cells. Oncotarget. PMID 26506420 DOI: 10.18632/oncotarget.5813  0.437
2015 Mu PF, Lee MY, Sheng CC, Tung PC, Huang LY, Chen YW. The experiences of family members in the year following the diagnosis of a child or adolescent with cancer: a qualitative systematic review. Jbi Database of Systematic Reviews and Implementation Reports. 13: 293-329. PMID 26455612 DOI: 10.11124/jbisrir-2015-1698  0.312
2015 Chen Y, Duda DG. Targeting immunosuppression after standard sorafenib treatment to facilitate immune checkpoint blockade in hepatocellular carcinoma - an auto-commentary on clinical potential and future development. Oncoimmunology. 4: e1029703. PMID 26451297 DOI: 10.1080/2162402X.2015.1029703  0.425
2015 Ni C, Huang L, Chen Y, He M, Hu Y, Liu S, Fang X, Li J, Sun Q, Wang X. Implication of cell-in-cell structures in the transmission of HIV to epithelial cells. Cell Research. PMID 26427717 DOI: 10.1038/cr.2015.119  0.318
2015 Zhao DJ, Chen Y, Wang ZY, Xue L, Mao TL, Liu YM, Wang ZY, Huang L. High-resolution non-contact measurement of the electrical activity of plants in situ using optical recording. Scientific Reports. 5: 13425. PMID 26333536 DOI: 10.1038/srep13425  0.317
2015 Lu YM, Pan J, Zhang WN, Hui AL, Guo WQ, Huang L, Zhu QJ, Chen Y. Synthesis, in silico and in vivo blood brain barrier permeability of ginkgolide B cinnamate. Fitoterapia. 106: 110-114. PMID 26327588 DOI: 10.1016/j.fitote.2015.08.012  0.367
2015 Yuh JY, Lin SW, Huang LJ, Fung HS, Lee LL, Chen YJ, Cheng CP, Chin YY, Lin HJ. Upgrade of beamline BL08B at Taiwan Light Source from a photon-BPM to a double-grating SGM beamline. Journal of Synchrotron Radiation. 22: 1312-8. PMID 26289286 DOI: 10.1107/S1600577515014009  0.304
2015 Liu JY, Chiang T, Liu CH, Chern GG, Lin TT, Gao DY, Chen Y. Delivery of siRNA Using CXCR4-targeted Nanoparticles Modulates Tumor Microenvironment and Achieves a Potent Antitumor Response in Liver Cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26278330 DOI: 10.1038/Mt.2015.147  0.842
2015 Li S, Chen SJ, Chen Y. An ab initio investigation on the ground electronic state of chlorine monoxide and its singly charged cation and anion. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 152: 453-460. PMID 26247329 DOI: 10.1016/j.saa.2015.07.100  0.472
2015 Gao DY, Lin TT, Sung YC, Liu YC, Chiang WH, Chang CC, Liu JY, Chen Y. CXCR4-targeted lipid-coated PLGA nanoparticles deliver sorafenib and overcome acquired drug resistance in liver cancer. Biomaterials. 67: 194-203. PMID 26218745 DOI: 10.1016/J.Biomaterials.2015.07.035  0.84
2015 Reiberger T, Chen Y, Ramjiawan RR, Hato T, Fan C, Samuel R, Roberge S, Huang P, Lauwers GY, Zhu AX, Bardeesy N, Jain RK, Duda DG. An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis. Nature Protocols. 10: 1264-1274. PMID 26203823 DOI: 10.1038/Nprot.2015.080  0.455
2015 Chen Y, Ramjiawan RR, Reiberger T, Ng MR, Hato T, Huang Y, Ochiai H, Kitahara S, Unan EC, Reddy TP, Fan C, Huang P, Bardeesy N, Zhu AX, Jain RK, et al. CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice. Hepatology (Baltimore, Md.). 61: 1591-602. PMID 25529917 DOI: 10.1002/Hep.27665  0.464
2015 Chen Y, Gao DY, Huang L. In vivo delivery of miRNAs for cancer therapy: challenges and strategies. Advanced Drug Delivery Reviews. 81: 128-41. PMID 24859533 DOI: 10.1016/J.Addr.2014.05.009  0.773
2015 Chen Y, Reiberger T, Ramjiawan R, Ng MR, Hato T, Unan EC, Reddy TP, Ochiai H, Huang P, Zhu AX, Jain RK, Duda DG. Abstract B79: CXCR4 inhibition facilitates anti-PD-1 immunotherapy by reprogramming the tumor microenvironment during sorafenib treatment in hepatocellular carcinoma Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-B79  0.451
2014 Chen Y, Huang Y, Reiberger T, Duyverman AM, Huang P, Samuel R, Hiddingh L, Roberge S, Koppel C, Lauwers GY, Zhu AX, Jain RK, Duda DG. Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice. Hepatology (Baltimore, Md.). 59: 1435-47. PMID 24242874 DOI: 10.1002/Hep.26790  0.479
2010 Chen Y, Bathula SR, Yang Q, Huang L. Targeted nanoparticles deliver siRNA to melanoma. The Journal of Investigative Dermatology. 130: 2790-8. PMID 20686495 DOI: 10.1038/Jid.2010.222  0.564
2010 Chen Y, Zhu X, Zhang X, Liu B, Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1650-6. PMID 20606648 DOI: 10.1038/Mt.2010.136  0.551
2010 Chen Y, Bathula SR, Li J, Huang L. Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. The Journal of Biological Chemistry. 285: 22639-50. PMID 20460382 DOI: 10.1074/Jbc.M110.125906  0.553
2010 Chen Y, Wu JJ, Huang L. Nanoparticles targeted with NGR motif deliver c-myc siRNA and doxorubicin for anticancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 828-34. PMID 20068551 DOI: 10.1038/Mt.2009.291  0.567
2010 Li J, Chen YC, Tseng YC, Mozumdar S, Huang L. Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 416-21. PMID 19919845 DOI: 10.1016/j.jconrel.2009.11.008  0.667
2009 Chen Y, Sen J, Bathula SR, Yang Q, Fittipaldi R, Huang L. Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells. Molecular Pharmaceutics. 6: 696-705. PMID 19267451 DOI: 10.1021/Mp800136V  0.552
2008 Chen Y, Huang L. Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy. Expert Opinion On Drug Delivery. 5: 1301-11. PMID 19040393 DOI: 10.1517/17425240802568505  0.558
2008 Li SD, Chen YC, Hackett MJ, Huang L. Tumor-targeted delivery of siRNA by self-assembled nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 163-9. PMID 17923843 DOI: 10.1038/Sj.Mt.6300323  0.674
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