Stanley Perlman - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Microbiology Biology

254 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Shi J, Zheng J, Zhang X, Tai W, Compas R, Deno J, Jachym N, Verma AK, Wang G, Guan X, Odle AE, Wan Y, Li F, Perlman S, Qiao L, et al. A T cell-based SARS-CoV-2 spike protein vaccine provides protection without antibodies. Jci Insight. 9. PMID 38456504 DOI: 10.1172/jci.insight.155789  0.315
2024 Li K, Verma A, Li P, Ortiz ME, Hawkins GM, Schnicker NJ, Szachowicz PJ, Pezullo A, Wohlford-Lenane CL, Kicmal T, Meyerholz DK, Gallagher T, Perlman S, McCray PB. Adaptation of SARS-CoV-2 to ACE2 mice reveals new spike residues that drive mouse infection. Journal of Virology. e0151023. PMID 38168680 DOI: 10.1128/jvi.01510-23  0.386
2023 Li P, Kim Y, Dampalla CS, Nhat Nguyen H, Meyerholz DK, Johnson DK, Lovell S, Groutas WC, Perlman S, Chang K-O. Potent 3CLpro inhibitors effective against SARS-CoV-2 and MERS-CoV in animal models by therapeutic treatment. Mbio. e0287823. PMID 38126789 DOI: 10.1128/mbio.02878-23  0.305
2023 Pan R, Meyerholz DK, Perlman S. Cells that survive acute murine SARS-CoV-2 infection are detected nearly exclusively in the respiratory tract. The Journal of Clinical Investigation. 133. PMID 37966119 DOI: 10.1172/JCI172659  0.314
2023 Wong L-YR, Odle A, Luhmann E, Wu DC, Wang Y, Teo QW, Ptak C, Sariol A, Lowery S, Mack M, Meyerholz DK, Wu NC, Radoshevich L, Perlman S. Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice. Mbio. e0247623. PMID 37882568 DOI: 10.1128/mbio.02476-23  0.378
2023 Fumagalli V, Di Lucia P, Ravà M, Marotta D, Bono E, Grassi S, Donnici L, Cannalire R, Stefanelli I, Ferraro A, Esposito F, Pariani E, Inverso D, Montesano C, Delbue S, ... Perlman S, et al. Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses. Embo Molecular Medicine. e17580. PMID 36946379 DOI: 10.15252/emmm.202317580  0.364
2023 Zheng J, Channappanavar R, Perlman S. Immunization of MERS-CoV-2-infected mice with a sublethal dose of MERS-CoV or VRP-MERS-S. Star Protocols. 4: 102171. PMID 36920912 DOI: 10.1016/j.xpro.2023.102171  0.355
2023 Honrubia JM, Gutierrez-Álvarez J, Sanz-Bravo A, González-Miranda E, Muñoz-Santos D, Castaño-Rodriguez C, Wang L, Villarejo-Torres M, Ripoll-Gómez J, Esteban A, Fernandez-Delgado R, Sánchez-Cordón PJ, Oliveros JC, Perlman S, McCray PB, et al. SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators. Mbio. e0313622. PMID 36625656 DOI: 10.1128/mbio.03136-22  0.341
2022 Verma AK, Zheng J, Meyerholz DK, Perlman S. SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways. Jci Insight. PMID 36378534 DOI: 10.1172/jci.insight.160277  0.302
2022 Meng W, Guo S, Cao S, Shuda M, Robinson-McCarthy LR, McCarthy KR, Shuda Y, Paniz Mondolfi AE, Bryce C, Grimes Z, Sordillo EM, Cordon-Cardo C, Li P, Zhang H, Perlman S, et al. Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp). Journal of Medical Virology. PMID 36271490 DOI: 10.1002/jmv.28246  0.313
2022 El-Kafrawy SA, Odle A, Abbas AT, Hassan AM, Abdel-Dayem UA, Qureshi AK, Wong LR, Zheng J, Meyerholz DK, Perlman S, Zumla A, Azhar EI. SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice. Plos Pathogens. 18: e1010782. PMID 36121829 DOI: 10.1371/journal.ppat.1010782  0.363
2022 Comar CE, Otter CJ, Pfannenstiel J, Doerger E, Renner DM, Tan LH, Perlman S, Cohen NA, Fehr AR, Weiss SR. MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123208119. PMID 35594398 DOI: 10.1073/pnas.2123208119  0.716
2022 Dijkman R, Verma AK, Selvaraj M, Ghimire R, Gad HH, Hartmann R, More S, Perlman S, Thiel V, Channappanavar R. Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice. Journal of Virology. e0036422. PMID 35588276 DOI: 10.1128/jvi.00364-22  0.372
2022 Channappanavar R, Selvaraj M, More S, Perlman S. Alveolar macrophages protect mice from MERS-CoV-induced pneumonia and severe disease. Veterinary Pathology. 3009858221095270. PMID 35499307 DOI: 10.1177/03009858221095270  0.426
2022 Sariol A, Zhao J, Abrahante JE, Perlman S. Virus-Specific Regulatory T Cells Persist as Memory in a Neurotropic Coronavirus Infection. Journal of Immunology (Baltimore, Md. : 1950). 208: 1989-1997. PMID 35365567 DOI: 10.4049/jimmunol.2100794  0.452
2022 Pan R, Kindler E, Cao L, Zhou Y, Zhang Z, Liu Q, Ebert N, Züst R, Sun Y, Gorbalenya AE, Perlman S, Thiel V, Chen Y, Guo D. N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition. Mbio. e0366221. PMID 35073761 DOI: 10.1128/mbio.03662-21  0.41
2022 Halfmann PJ, Iida S, Iwatsuki-Horimoto K, Maemura T, Kiso M, Scheaffer SM, Darling TL, Joshi A, Loeber S, Singh G, Foster SL, Ying B, Case JB, Chong Z, Whitener B, ... ... Perlman S, et al. SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters. Nature. PMID 35062015 DOI: 10.1038/s41586-022-04441-6  0.325
2022 Peiris M, Perlman S. Unresolved questions in the zoonotic transmission of MERS. Current Opinion in Virology. 52: 258-264. PMID 34999369 DOI: 10.1016/j.coviro.2021.12.013  0.329
2021 Comar CE, Otter CJ, Pfannenstiel J, Doerger E, Renner DM, Tan LH, Perlman S, Cohen NA, Fehr AR, Weiss SR. MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells. Biorxiv : the Preprint Server For Biology. PMID 34981054 DOI: 10.1101/2021.12.20.473564  0.737
2021 Diamond M, Halfmann P, Maemura T, Iwatsuki-Horimoto K, Iida S, Kiso M, Scheaffer S, Darling T, Joshi A, Loeber S, Foster S, Ying B, Whitener B, Floyd K, Ujie M, ... ... Perlman S, et al. The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters. Research Square. PMID 34981044 DOI: 10.21203/rs.3.rs-1211792/v1  0.349
2021 Malicoat J, Manivasagam S, Zuñiga S, Sola I, McCabe D, Rong L, Perlman S, Enjuanes L, Manicassamy B. Development of a Single-cycle Infectious SARS-CoV-2 Virus Replicon Particle System for use in BSL2 Laboratories. Journal of Virology. JVI0183721. PMID 34851142 DOI: 10.1128/JVI.01837-21  0.349
2021 Wong LR, Perlman S. Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses - are we our own worst enemy? Nature Reviews. Immunology. PMID 34837062 DOI: 10.1038/s41577-021-00656-2  0.32
2021 Verma AK, Zheng J, Mack M, Ginhoux F, Perlman S. Differential Effects of Prostaglandin D Signaling on Macrophages and Microglia in Murine Coronavirus Encephalomyelitis. Mbio. e0196921. PMID 34488442 DOI: 10.1128/mBio.01969-21  0.374
2021 Wang Y, Perlman S. COVID-19: Inflammatory Profile. Annual Review of Medicine. PMID 34437814 DOI: 10.1146/annurev-med-042220-012417  0.339
2021 Qing E, Kicmal T, Kumar B, Hawkins GM, Timm E, Perlman S, Gallagher T. Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains. Mbio. e0159021. PMID 34340537 DOI: 10.1128/mBio.01590-21  0.356
2021 Dampalla CS, Zheng J, Perera KD, Wong LR, Meyerholz DK, Nguyen HN, Kashipathy MM, Battaile KP, Lovell S, Kim Y, Perlman S, Groutas WC, Chang KO. Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34210738 DOI: 10.1073/pnas.2101555118  0.368
2021 Chu H, Shuai H, Hou Y, Zhang X, Wen L, Huang X, Hu B, Yang D, Wang Y, Yoon C, Wong BH, Li C, Zhao X, Poon VK, Cai JP, ... ... Perlman S, et al. Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity. Science Advances. 7. PMID 34134991 DOI: 10.1126/sciadv.abf8577  0.305
2021 Zheng J, Meyerholz D, Wong LR, Gelb M, Murakami M, Perlman S. Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. The Journal of Clinical Investigation. 131. PMID 34060490 DOI: 10.1172/JCI147201  0.461
2021 Roy Wong LY, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Pezzulo AA, Szachowicz PJ, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Meyerholz DK, Fortney K, ... ... Perlman S, et al. Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19. Biorxiv : the Preprint Server For Biology. PMID 33907749 DOI: 10.1101/2021.04.20.440676  0.317
2021 Zheng J, Wen L, Yen HL, Liu M, Liu Y, Teng O, Wu WF, Ni K, Lam KT, Huang C, Yang J, Lau YL, Perlman S, Peiris M, Tu W. Phenotypic and functional characteristics of a novel influenza hemagglutinin-specific memory NK cell. Journal of Virology. PMID 33827945 DOI: 10.1128/JVI.00165-21  0.37
2020 Heer CD, Sanderson DJ, Voth LS, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C. Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity. The Journal of Biological Chemistry. 295: 17986-17996. PMID 33453811 DOI: 10.1074/jbc.RA120.015138  0.332
2020 Wong LR, Li K, Sun J, Zhuang Z, Zhao J, McCray PB, Perlman S. Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2. Star Protocols. 1: 100169. PMID 33377063 DOI: 10.1016/j.xpro.2020.100169  0.314
2020 Zheng J, Wang Y, Li K, Meyerholz DK, Allamargot C, Perlman S. SARS-CoV-2-induced immune activation and death of monocyte-derived human macrophages and dendritic cells. The Journal of Infectious Diseases. PMID 33277988 DOI: 10.1093/infdis/jiaa753  0.343
2020 Meyerholz DK, Perlman S. Does common cold coronavirus infection protect against severe SARS-CoV2 disease? The Journal of Clinical Investigation. PMID 33216734 DOI: 10.1172/JCI144807  0.313
2020 Zheng J, Wong LR, Li K, Verma AK, Ortiz M, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S. COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature. PMID 33166988 DOI: 10.1038/s41586-020-2943-z  0.321
2020 Ghosh S, Dellibovi-Ragheb TA, Kerviel A, Pak E, Qiu Q, Fisher M, Takvorian PM, Bleck C, Hsu VW, Fehr AR, Perlman S, Achar SR, Straus MR, Whittaker GR, de Haan CAM, et al. β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell. PMID 33157038 DOI: 10.1016/j.cell.2020.10.039  0.649
2020 Gutierrez-Alvarez J, Wang L, Fernandez-Delgado R, Li K, McCray PB, Perlman S, Sola I, Zuñiga S, Enjuanes L. Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice. Journal of Virology. PMID 33144319 DOI: 10.1128/JVI.01172-20  0.433
2020 Channappanavar R, Perlman S. Age-related susceptibility to Coronavirus infections: role of impaired and dysregulated host immunity. The Journal of Clinical Investigation. PMID 33085654 DOI: 10.1172/JCI144115  0.365
2020 Heer CD, Sanderson DJ, Voth LS, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C. Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity. The Journal of Biological Chemistry. PMID 33051211 DOI: 10.1074/jbc.RA120.015138  0.72
2020 Sariol A, Mackin S, Allred MG, Ma C, Zhou Y, Zhang Q, Zou X, Abrahante JE, Meyerholz DK, Perlman S. Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929007 DOI: 10.1073/Pnas.2007814117  0.458
2020 Wang Y, Grunewald M, Perlman S. Coronaviruses: An Updated Overview of Their Replication and Pathogenesis. Methods in Molecular Biology (Clifton, N.J.). 2203: 1-29. PMID 32833200 DOI: 10.1007/978-1-0716-0900-2_1  0.44
2020 Zheng J, Roy Wong LY, Li K, Verma AK, Ortiz M, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S. K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia. Biorxiv : the Preprint Server For Biology. PMID 32817939 DOI: 10.1101/2020.08.07.242073  0.311
2020 Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Science Translational Medicine. PMID 32747425 DOI: 10.1126/Scitranslmed.Abc5332  0.458
2020 Sariol A, Perlman S. Lessons for COVID-19 Immunity from Other Coronavirus Infections. Immunity. PMID 32717182 DOI: 10.1016/J.Immuni.2020.07.005  0.419
2020 Sun J, Zhuang Z, Zheng J, Li K, Wong RL, Liu D, Huang J, He J, Zhu A, Zhao J, Li X, Xi Y, Chen R, Alshukairi AN, Chen Z, ... ... Perlman S, et al. Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell. PMID 32643603 DOI: 10.1016/J.Cell.2020.06.010  0.382
2020 Wang Y, Zhang L, Sang L, Ye F, Ruan S, Zhong B, Song T, Alshukairi AN, Chen R, Zhang Z, Gan M, Zhu A, Huang Y, Luo L, Mok CK, ... ... Perlman S, et al. Kinetics of viral load and antibody response in relation to COVID-19 severity. The Journal of Clinical Investigation. PMID 32634129 DOI: 10.1172/Jci138759  0.365
2020 Zheng J, Sariol A, Meyerholz D, Zhang Q, Abrahante Lloréns JE, Narumiya S, Perlman S. Prostaglandin D2 signaling in dendritic cells is critical for the development of EAE. Journal of Autoimmunity. 102508. PMID 32624353 DOI: 10.1016/J.Jaut.2020.102508  0.384
2020 Pan R, Zhang Q, Anthony SM, Zhou Y, Zou X, Cassell M, Perlman S. Oligodendrocytes that survive acute coronavirus infection induce prolonged inflammatory responses in the CNS. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571951 DOI: 10.1073/Pnas.2003432117  0.482
2020 Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, ... ... Perlman S, et al. A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies. Cell. PMID 32553273 DOI: 10.1016/J.Cell.2020.06.011  0.479
2020 Heer CD, Sanderson DJ, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C. Coronavirus and PARP expression dysregulate the NAD Metabolome: a potentially actionable component of innate immunity. Biorxiv : the Preprint Server For Biology. PMID 32511303 DOI: 10.1101/2020.04.17.047480  0.699
2020 Li K, Li Z, Wohlford-Lenane C, Meyerholz DK, Channappanavar R, An D, Perlman S, McCray PB, He B. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. Mbio. 11. PMID 32265331 DOI: 10.1128/Mbio.00554-20  0.447
2020 Poh CM, Zheng J, Channappanavar R, Chang ZW, Nguyen THO, Rénia L, Kedzierska K, Perlman S, Poon LLM. Multiplex Screening Assay for Identifying Cytotoxic CD8 T Cell Epitopes. Frontiers in Immunology. 11: 400. PMID 32218786 DOI: 10.3389/Fimmu.2020.00400  0.388
2020 Qing E, Hantak M, Perlman S, Gallagher T. Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection. Mbio. 11. PMID 32047128 DOI: 10.1128/Mbio.02764-19  0.478
2020 Perlman S. Another Decade, Another Coronavirus. The New England Journal of Medicine. PMID 31978944 DOI: 10.1056/Nejme2001126  0.395
2020 Channappanavar R, Perlman S. Evaluation of Activation and Inflammatory Activity of Myeloid Cells During Pathogenic Human Coronavirus Infection. Methods in Molecular Biology (Clifton, N.J.). 2099: 195-204. PMID 31883097 DOI: 10.1007/978-1-0716-0211-9_15  0.429
2019 Zheng J, Hassan S, Alagaili AN, Alshukairi AN, Amor NMS, Mukhtar N, Nazeer IM, Tahir Z, Akhter N, Perlman S, Yaqub T. Middle East Respiratory Syndrome Coronavirus Seropositivity in Camel Handlers and Their Families, Pakistan. Emerging Infectious Diseases. 25. PMID 31742530 DOI: 10.3201/Eid2512.191169  0.365
2019 Grunewald ME, Shaban MG, Mackin SR, Fehr AR, Perlman S. Murine coronavirus infection activates AhR in an IDO1-independent manner contributing to cytokine modulation and pro-viral TiPARP expression. Journal of Virology. PMID 31694960 DOI: 10.1128/Jvi.01743-19  0.774
2019 Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB, Meyerholz DK, Perlman S. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. The Journal of Clinical Investigation. 130. PMID 31355779 DOI: 10.1172/Jci126363  0.779
2019 Jia W, Channappanavar R, Zhang C, Li M, Zhou H, Zhang S, Zhou P, Xu J, Shan S, Shi X, Wang X, Zhao J, Zhou D, Perlman S, Zhang L. Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection. Emerging Microbes & Infections. 8: 760-772. PMID 31130102 DOI: 10.1080/22221751.2019.1620083  0.629
2019 Grunewald ME, Chen Y, Kuny C, Maejima T, Lease R, Ferraris D, Aikawa M, Sullivan CS, Perlman S, Fehr AR. The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression. Plos Pathogens. 15: e1007756. PMID 31095648 DOI: 10.1371/Journal.Ppat.1007756  0.737
2019 Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, Tang H, Nishiura K, Peng J, Tan Z, Wu T, Cheung KW, Chan KH, Alvarez X, Qin C, ... ... Perlman S, et al. Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection. Jci Insight. 4. PMID 30830861 DOI: 10.1172/Jci.Insight.123158  0.428
2019 Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, ... ... Perlman S, et al. SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nature Communications. 10: 120. PMID 30631056 DOI: 10.1038/S41467-018-08015-X  0.426
2018 Alshukairi AN, Zheng J, Zhao J, Nehdi A, Baharoon SA, Layqah L, Bokhari A, Al Johani SM, Samman N, Boudjelal M, Ten Eyck P, Al-Mozaini MA, Zhao J, Perlman S, Alagaili AN. High Prevalence of MERS-CoV Infection in Camel Workers in Saudi Arabia. Mbio. 9. PMID 30377284 DOI: 10.1128/Mbio.01985-18  0.461
2018 Perlman S, Gallagher T. Not your usual tRNA synthetase: hWARS serves as an enterovirus entry factor. The Journal of Clinical Investigation. PMID 30320601 DOI: 10.1172/Jci124582  0.394
2018 Hua X, Vijay R, Channappanvar R, Athmer J, Meyerholz DK, Pagedar N, Tilley S, Perlman S. Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia. Jci Insight. 3. PMID 29875310 DOI: 10.1172/Jci.Insight.99025  0.437
2018 Castaño-Rodriguez C, Honrubia JM, Gutiérrez-Álvarez J, DeDiego ML, Nieto-Torres JL, Jimenez-Guardeño JM, Regla-Nava JA, Fernandez-Delgado R, Verdia-Báguena C, Queralt-Martín M, Kochan G, Perlman S, Aguilella VM, Sola I, Enjuanes L. Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis. Mbio. 9. PMID 29789363 DOI: 10.1128/Mbio.02325-17  0.358
2018 Athmer J, Fehr AR, Grunewald ME, Qu W, Wheeler DL, Graepel KW, Channappanavar R, Sekine A, Aldabeeb DS, Gale M, Denison MR, Perlman S. Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses. Mbio. 9. PMID 29717007 DOI: 10.1128/Mbio.00272-18  0.712
2018 Galasiti Kankanamalage AC, Kim Y, Damalanka VC, Rathnayake AD, Fehr AR, Mehzabeen N, Battaile KP, Lovell S, Lushington GH, Perlman S, Chang KO, Groutas WC. Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. European Journal of Medicinal Chemistry. 150: 334-346. PMID 29544147 DOI: 10.1016/J.Ejmech.2018.03.004  0.668
2018 Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, ... ... Perlman S, et al. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507189 DOI: 10.1073/Pnas.1718769115  0.463
2018 Wheeler DL, Sariol A, Meyerholz DK, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. The Journal of Clinical Investigation. PMID 29376888 DOI: 10.1172/Jci97229  0.548
2018 Canton J, Fehr AR, Fernandez-Delgado R, Gutierrez-Alvarez FJ, Sanchez-Aparicio MT, García-Sastre A, Perlman S, Enjuanes L, Sola I. MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection. Plos Pathogens. 14: e1006838. PMID 29370303 DOI: 10.1371/Journal.Ppat.1006838  0.702
2017 Fehr AR, Jankevicius G, Ahel I, Perlman S. Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis. Trends in Microbiology. PMID 29268982 DOI: 10.1016/J.Tim.2017.11.011  0.72
2017 Grunewald ME, Fehr AR, Athmer J, Perlman S. The coronavirus nucleocapsid protein is ADP-ribosylated. Virology. PMID 29199039 DOI: 10.1016/J.Virol.2017.11.020  0.744
2017 Zheng J, Perlman S. Immune responses in influenza A virus and human coronavirus infections: an ongoing battle between the virus and host. Current Opinion in Virology. 28: 43-52. PMID 29172107 DOI: 10.1016/J.Coviro.2017.11.002  0.454
2017 Wheeler DL, Athmer J, Meyerholz DK, Perlman S. Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus. Journal of Virology. PMID 28835503 DOI: 10.1128/Jvi.01099-17  0.485
2017 Zhao J, Alshukairi AN, Baharoon SA, Ahmed WA, Bokhari AA, Nehdi AM, Layqah LA, Alghamdi MG, Al Gethamy MM, Dada AM, Khalid I, Boujelal M, Al Johani SM, Vogel L, Subbarao K, ... ... Perlman S, et al. Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses. Science Immunology. 2. PMID 28778905 DOI: 10.1126/Sciimmunol.Aan5393  0.488
2017 Earnest JT, Hantak MP, Li K, McCray PB, Perlman S, Gallagher T. The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. Plos Pathogens. 13: e1006546. PMID 28759649 DOI: 10.1371/Journal.Ppat.1006546  0.456
2017 Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630327 DOI: 10.1073/Pnas.1704099114  0.704
2017 Wang Y, Sun J, Channappanavar R, Zhao J, Perlman S, Zhao J. Simultaneous Intranasal/Intravascular Antibody Labeling of CD4(+) T Cells in Mouse Lungs. Bio-Protocol. 7. PMID 28516121 DOI: 10.21769/BioProtoc.2099  0.329
2017 Channappanavar R, Perlman S. Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology. Seminars in Immunopathology. PMID 28466096 DOI: 10.1007/S00281-017-0629-X  0.483
2017 Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28373583 DOI: 10.4049/Jimmunol.1601896  0.448
2017 Li K, Wohlford-Lenane CL, Channappanavar R, Park JE, Earnest JT, Bair TB, Bates AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348219 DOI: 10.1073/Pnas.1619109114  0.49
2017 Chi H, Zheng X, Wang X, Wang C, Wang H, Gai W, Perlman S, Yang S, Zhao J, Xia X. DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice. Vaccine. PMID 28314561 DOI: 10.1016/J.Vaccine.2017.02.063  0.388
2017 Athmer J, Fehr AR, Grunewald M, Smith EC, Denison MR, Perlman S. In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins. Mbio. 8. PMID 28143984 DOI: 10.1128/Mbio.02320-16  0.705
2017 Perlman S, Zhao J. Roles of regulatory T cells and IL-10 in virus-induced demyelination. Journal of Neuroimmunology. PMID 28065579 DOI: 10.1016/J.Jneuroim.2017.01.001  0.571
2016 Cui J, Zhao Y, Wang H, Qiu B, Cao Z, Li Q, Zhang Y, Yan F, Jin H, Wang T, Sun W, Feng N, Gao Y, Sun J, Wang Y, ... Perlman S, et al. Equine Immunoglobulin and Equine Neutralizing F(ab')₂ Protect Mice from West Nile Virus Infection. Viruses. 8. PMID 27999340 DOI: 10.3390/V8120332  0.492
2016 Fehr AR, Channappanavar R, Jankevicius G, Fett C, Zhao J, Athmer J, Meyerholz DK, Ahel I, Perlman S. The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection. Mbio. 7. PMID 27965448 DOI: 10.1128/Mbio.01721-16  0.784
2016 Zhao Y, Wang C, Qiu B, Li C, Wang H, Jin H, Gai W, Zheng X, Wang T, Sun W, Yan F, Gao Y, Wang Q, Yan J, Chen L, ... Perlman S, et al. Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model. Antiviral Research. PMID 27890674 DOI: 10.1016/J.Antiviral.2016.11.016  0.504
2016 de Wilde AH, Falzarano D, Zevenhoven-Dobbe JC, Beugeling C, Fett C, Martellaro C, Posthuma CC, Feldmann H, Perlman S, Snijder EJ. Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model. Virus Research. PMID 27840112 DOI: 10.1016/J.Virusres.2016.11.011  0.44
2016 Tai W, Wang Y, Fett CA, Zhao G, Li F, Perlman S, Jiang S, Zhou Y, Du L. Recombinant receptor-binding domains of multiple MERS-coronaviruses induce cross-neutralizing antibodies against divergent human and camel MERS-coronaviruses and antibody-escape mutants. Journal of Virology. PMID 27795425 DOI: 10.1128/Jvi.01651-16  0.365
2016 Park JE, Li K, Barlan A, Fehr AR, Perlman S, McCray PB, Gallagher T. Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism. Proceedings of the National Academy of Sciences of the United States of America. 113: 12262-12267. PMID 27791014 DOI: 10.1073/Pnas.1608147113  0.756
2016 Fehr AR, Channappanavar R, Perlman S. Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus. Annual Review of Medicine. PMID 27576010 DOI: 10.1146/Annurev-Med-051215-031152  0.731
2016 Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity. PMID 27287409 DOI: 10.1016/J.Immuni.2016.05.006  0.479
2016 Zhao J, Vijay R, Zhao J, Gale M, Diamond MS, Perlman S. MAVS expressed by hematopoietic cells is critical for control of West Nile virus infection and pathogenesis. Journal of Virology. PMID 27226371 DOI: 10.1128/Jvi.00707-16  0.569
2016 Alshukairi AN, Khalid I, Ahmed WA, Dada AM, Bayumi DT, Malic LS, Althawadi S, Ignacio K, Alsalmi HS, Al-Abdely HM, Wali GY, Qushmaq IA, Alraddadi BM, Perlman S. Antibody Response and Disease Severity in Healthcare Worker MERS Survivors. Emerging Infectious Diseases. 22. PMID 27192543 DOI: 10.3201/Eid2206.160010  0.32
2016 Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, ... ... Perlman S, et al. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Science Translational Medicine. 8: 326ra21. PMID 26888429 DOI: 10.1126/Scitranslmed.Aaf1061  0.366
2016 Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, Perlman S. Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice. Cell Host & Microbe. 19: 181-93. PMID 26867177 DOI: 10.1016/J.Chom.2016.01.007  0.772
2016 Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Current Opinion in Virology. 16: 70-76. PMID 26855039 DOI: 10.1016/J.Coviro.2016.01.011  0.476
2016 Bedell K, Buchaklian AH, Perlman S. Efficacy of an Automated Multiple Emitter Whole-Room Ultraviolet-C Disinfection System Against Coronaviruses MHV and MERS-CoV. Infection Control and Hospital Epidemiology. 1-2. PMID 26818469 DOI: 10.1017/Ice.2015.348  0.365
2015 Jimenez-Guardeño JM, Regla-Nava JA, Nieto-Torres JL, DeDiego ML, Castaño-Rodriguez C, Fernandez-Delgado R, Perlman S, Enjuanes L. Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine. Plos Pathogens. 11: e1005215. PMID 26513244 DOI: 10.1371/Journal.Ppat.1005215  0.385
2015 Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB. Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. The Journal of Infectious Diseases. PMID 26486634 DOI: 10.1093/Infdis/Jiv499  0.488
2015 Vijay R, Hua X, Meyerholz DK, Miki Y, Yamamoto K, Gelb M, Murakami M, Perlman S. Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection. The Journal of Experimental Medicine. PMID 26392224 DOI: 10.1084/Jem.20150632  0.47
2015 Li Y, Wan Y, Liu P, Zhao J, Lu G, Qi J, Wang Q, Lu X, Wu Y, Liu W, Zhang B, Yuen KY, Perlman S, Gao GF, Yan J. A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Research. PMID 26391698 DOI: 10.1038/Cr.2015.113  0.391
2015 Corti D, Zhao J, Pedotti M, Simonelli L, Agnihothram S, Fett C, Fernandez-Rodriguez B, Foglierini M, Agatic G, Vanzetta F, Gopal R, Langrish CJ, Barrett NA, Sallusto F, Baric RS, ... ... Perlman S, et al. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proceedings of the National Academy of Sciences of the United States of America. 112: 10473-8. PMID 26216974 DOI: 10.1073/Pnas.1510199112  0.476
2015 Perlman S. Research Driven by Curiosity: The Journey from Basic Molecular Biology and Virology to Studies of Human Pathogenic Coronaviruses. Plos Pathogens. 11: e1005023. PMID 26172373 DOI: 10.1371/Journal.Ppat.1005023  0.568
2015 Channappanavar R, Lu L, Xia S, Du L, Meyerholz DK, Perlman S, Jiang S. Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection. The Journal of Infectious Diseases. PMID 26164863 DOI: 10.1093/Infdis/Jiv325  0.44
2015 Zumla A, Hui DS, Perlman S. Middle East respiratory syndrome. Lancet. PMID 26049252 DOI: 10.1016/S0140-6736(15)60454-8  0.374
2015 Zhao J, Perera RA, Kayali G, Meyerholz D, Perlman S, Peiris M. Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection. Journal of Virology. 89: 6117-20. PMID 25787284 DOI: 10.1128/Jvi.00446-15  0.441
2015 Fehr AR, Perlman S. Coronaviruses: an overview of their replication and pathogenesis. Methods in Molecular Biology (Clifton, N.J.). 1282: 1-23. PMID 25720466 DOI: 10.1007/978-1-4939-2438-7_1  0.718
2015 Mielech AM, Deng X, Chen Y, Kindler E, Wheeler DL, Mesecar AD, Thiel V, Perlman S, Baker SC. Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. Journal of Virology. 89: 4907-17. PMID 25694594 DOI: 10.1128/Jvi.00338-15  0.441
2015 Zhang N, Channappanavar R, Ma C, Wang L, Tang J, Garron T, Tao X, Tasneem S, Lu L, Tseng CT, Zhou Y, Perlman S, Jiang S, Du L. Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus. Cellular & Molecular Immunology. PMID 25640653 DOI: 10.1038/Cmi.2015.03  0.356
2015 Regla-Nava JA, Nieto-Torres JL, Jimenez-Guardeño JM, Fernandez-Delgado R, Fett C, Castaño-Rodríguez C, Perlman S, Enjuanes L, DeDiego ML. Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates. Journal of Virology. 89: 3870-87. PMID 25609816 DOI: 10.1128/Jvi.03566-14  0.483
2015 Fehr AR, Athmer J, Channappanavar R, Phillips JM, Meyerholz DK, Perlman S. The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis. Journal of Virology. 89: 1523-36. PMID 25428866 DOI: 10.1128/Jvi.02596-14  0.783
2014 Fett C, Zhao J, Perlman S. Virus Infection and Titration of SARS-CoV in Mouse Lung. Bio-Protocol. 4. PMID 27390761  0.401
2014 Trujillo JA, Croft NP, Dudek NL, Channappanavar R, Theodossis A, Webb AI, Dunstone MA, Illing PT, Butler NS, Fett C, Tscharke DC, Rossjohn J, Perlman S, Purcell AW. The cellular redox environment alters antigen presentation. The Journal of Biological Chemistry. 289: 27979-91. PMID 25135637 DOI: 10.1074/Jbc.M114.573402  0.805
2014 Zhao J, Zhao J, Perlman S. Virus-specific regulatory T cells ameliorate encephalitis by repressing effector T cell functions from priming to effector stages. Plos Pathogens. 10: e1004279. PMID 25102154 DOI: 10.1371/Journal.Ppat.1004279  0.5
2014 Channappanavar R, Fett C, Zhao J, Meyerholz DK, Perlman S. Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection. Journal of Virology. 88: 11034-44. PMID 25056892 DOI: 10.1128/Jvi.01505-14  0.509
2014 Hemida MG, Perera RA, Al Jassim RA, Kayali G, Siu LY, Wang P, Chu KW, Perlman S, Ali MA, Alnaeem A, Guan Y, Poon LL, Saif L, Peiris M. Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity. Euro Surveillance : Bulletin Europã©En Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 19. PMID 24957744 DOI: 10.2807/1560-7917.Es2014.19.23.20828  0.352
2014 Channappanavar R, Zhao J, Perlman S. T cell-mediated immune response to respiratory coronaviruses. Immunologic Research. 59: 118-28. PMID 24845462 DOI: 10.1007/S12026-014-8534-Z  0.516
2014 Trujillo JA, Gras S, Twist KA, Croft NP, Channappanavar R, Rossjohn J, Purcell AW, Perlman S. Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes. Journal of Immunology (Baltimore, Md. : 1950). 192: 5245-56. PMID 24795457 DOI: 10.4049/Jimmunol.1400111  0.729
2014 Zhao J, Li K, Wohlford-Lenane C, Agnihothram SS, Fett C, Zhao J, Gale MJ, Baric RS, Enjuanes L, Gallagher T, McCray PB, Perlman S. Rapid generation of a mouse model for Middle East respiratory syndrome. Proceedings of the National Academy of Sciences of the United States of America. 111: 4970-5. PMID 24599590 DOI: 10.1073/Pnas.1323279111  0.557
2014 Lin SY, Liu CL, Chang YM, Zhao J, Perlman S, Hou MH. Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target. Journal of Medicinal Chemistry. 57: 2247-57. PMID 24564608 DOI: 10.1021/Jm500089R  0.313
2014 Barlan A, Zhao J, Sarkar MK, Li K, McCray PB, Perlman S, Gallagher T. Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection. Journal of Virology. 88: 4953-61. PMID 24554656 DOI: 10.1128/Jvi.00161-14  0.444
2014 DeDiego ML, Nieto-Torres JL, Regla-Nava JA, Jimenez-Guardeño JM, Fernandez-Delgado R, Fett C, Castaño-Rodriguez C, Perlman S, Enjuanes L. Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival. Journal of Virology. 88: 913-24. PMID 24198408 DOI: 10.1128/Jvi.02576-13  0.462
2013 Perlman S. The Middle East respiratory syndrome--how worried should we be? Mbio. 4. PMID 23963179 DOI: 10.1128/Mbio.00531-13  0.477
2013 Zhao J, Fett C, Pewe L, Zhao J, Perlman S. Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor. Journal of Immunological Methods. 396: 56-64. PMID 23928495 DOI: 10.1016/J.Jim.2013.07.011  0.452
2013 Perlman S, McCray PB. Person-to-person spread of the MERS coronavirus--an evolving picture. The New England Journal of Medicine. 369: 466-7. PMID 23902487 DOI: 10.1056/Nejme1308724  0.338
2013 Fett C, DeDiego ML, Regla-Nava JA, Enjuanes L, Perlman S. Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein. Journal of Virology. 87: 6551-9. PMID 23576515 DOI: 10.1128/Jvi.00087-13  0.456
2013 Chen IJ, Yuann JM, Chang YM, Lin SY, Zhao J, Perlman S, Shen YY, Huang TH, Hou MH. Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein. Biochimica Et Biophysica Acta. 1834: 1054-62. PMID 23501675 DOI: 10.1016/J.Bbapap.2013.03.003  0.316
2013 Gallagher T, Perlman S. Public health: Broad reception for coronavirus. Nature. 495: 176-7. PMID 23486053 DOI: 10.1038/495176A  0.47
2013 Perlman S, Zhao J. Human coronavirus EMC is not the same as severe acute respiratory syndrome coronavirus. Mbio. 4. PMID 23322635 DOI: 10.1128/Mbio.00002-13  0.407
2013 Trujillo JA, Fleming EL, Perlman S. Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection. Journal of Virology. 87: 2376-89. PMID 23269787 DOI: 10.1128/Jvi.03089-12  0.802
2012 Zhao J, Zhao J, Perlman S. Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-γ, IL-2 and IL-2R. Plos One. 7: e46241. PMID 23029447 DOI: 10.1371/Journal.Pone.0046241  0.315
2012 Zhao J, Wohlford-Lenane C, Zhao J, Fleming E, Lane TE, McCray PB, Perlman S. Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections. Journal of Virology. 86: 11416-24. PMID 22915814 DOI: 10.1128/Jvi.01410-12  0.464
2011 Zhao J, Zhao J, Legge K, Perlman S. Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. The Journal of Clinical Investigation. 121: 4921-30. PMID 22105170 DOI: 10.1172/Jci59777  0.489
2011 DeDiego ML, Nieto-Torres JL, Jiménez-Guardeño JM, Regla-Nava JA, Alvarez E, Oliveros JC, Zhao J, Fett C, Perlman S, Enjuanes L. Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis. Plos Pathogens. 7: e1002315. PMID 22028656 DOI: 10.1371/Journal.Ppat.1002315  0.425
2011 Zhao J, Zhao J, Fett C, Trandem K, Fleming E, Perlman S. IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis. The Journal of Experimental Medicine. 208: 1571-7. PMID 21746812 DOI: 10.1084/Jem.20110236  0.83
2011 Trandem K, Jin Q, Weiss KA, James BR, Zhao J, Perlman S. Virally expressed interleukin-10 ameliorates acute encephalomyelitis and chronic demyelination in coronavirus-infected mice. Journal of Virology. 85: 6822-31. PMID 21593179 DOI: 10.1128/Jvi.00510-11  0.816
2011 Trandem K, Zhao J, Fleming E, Perlman S. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 186: 3642-52. PMID 21317392 DOI: 10.4049/Jimmunol.1003292  0.809
2011 Shulla A, Heald-Sargent T, Subramanya G, Zhao J, Perlman S, Gallagher T. A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry. Journal of Virology. 85: 873-82. PMID 21068237 DOI: 10.1128/Jvi.02062-10  0.4
2010 Zhou H, Zhao J, Perlman S. Autocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infection. Mbio. 1. PMID 20978536 DOI: 10.1128/Mbio.00219-10  0.613
2010 Zhao J, Zhao J, Perlman S. T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice. Journal of Virology. 84: 9318-25. PMID 20610717 DOI: 10.1128/Jvi.01049-10  0.556
2010 Trandem K, Anghelina D, Zhao J, Perlman S. Regulatory T cells inhibit T cell proliferation and decrease demyelination in mice chronically infected with a coronavirus. Journal of Immunology (Baltimore, Md. : 1950). 184: 4391-400. PMID 20208000 DOI: 10.4049/Jimmunol.0903918  0.836
2010 Netland J, DeDiego ML, Zhao J, Fett C, Alvarez E, Nieto-Torres JL, Enjuanes L, Perlman S. Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease. Virology. 399: 120-8. PMID 20110095 DOI: 10.1016/J.Virol.2010.01.004  0.789
2010 Zhou H, Ferraro D, Zhao J, Hussain S, Shao J, Trujillo J, Netland J, Gallagher T, Perlman S. The N-terminal region of severe acute respiratory syndrome coronavirus protein 6 induces membrane rearrangement and enhances virus replication. Journal of Virology. 84: 3542-51. PMID 20106914 DOI: 10.1128/Jvi.02570-09  0.803
2009 Zhao J, Zhao J, Van Rooijen N, Perlman S. Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice. Plos Pathogens. 5: e1000636. PMID 19851468 DOI: 10.1371/Journal.Ppat.1000636  0.55
2009 Zhao J, Zhao J, Perlman S. De novo recruitment of antigen-experienced and naive T cells contributes to the long-term maintenance of antiviral T cell populations in the persistently infected central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 183: 5163-70. PMID 19786545 DOI: 10.4049/Jimmunol.0902164  0.529
2009 Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB. Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. Journal of Virology. 83: 11385-90. PMID 19710146 DOI: 10.1128/Jvi.01363-09  0.598
2009 Perlman S, Netland J. Coronaviruses post-SARS: update on replication and pathogenesis. Nature Reviews. Microbiology. 7: 439-50. PMID 19430490 DOI: 10.1038/Nrmicro2147  0.77
2009 Anghelina D, Zhao J, Trandem K, Perlman S. Role of regulatory T cells in coronavirus-induced acute encephalitis. Virology. 385: 358-67. PMID 19141357 DOI: 10.1016/J.Virol.2008.12.014  0.847
2009 Zhao J, Falcón A, Zhou H, Netland J, Enjuanes L, Pérez Breña P, Perlman S. Severe acute respiratory syndrome coronavirus protein 6 is required for optimal replication. Journal of Virology. 83: 2368-73. PMID 19091867 DOI: 10.1128/Jvi.02371-08  0.827
2009 Whitman L, Zhou H, Perlman S, Lane TE. IFN-gamma-mediated suppression of coronavirus replication in glial-committed progenitor cells. Virology. 384: 209-15. PMID 19059617 DOI: 10.1016/J.Virol.2008.10.036  0.63
2008 Butler NS, Theodossis A, Webb AI, Nastovska R, Ramarathinam SH, Dunstone MA, Rossjohn J, Purcell AW, Perlman S. Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. Plos Pathogens. 4: e1000186. PMID 18949029 DOI: 10.1371/Journal.Ppat.1000186  0.731
2008 Netland J, Meyerholz DK, Moore S, Cassell M, Perlman S. Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. Journal of Virology. 82: 7264-75. PMID 18495771 DOI: 10.1128/Jvi.00737-08  0.784
2008 Dediego ML, Pewe L, Alvarez E, Rejas MT, Perlman S, Enjuanes L. Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice. Virology. 376: 379-89. PMID 18452964 DOI: 10.1016/J.Virol.2008.03.005  0.458
2008 Hussain S, Perlman S, Gallagher TM. Severe acute respiratory syndrome coronavirus protein 6 accelerates murine hepatitis virus infections by more than one mechanism. Journal of Virology. 82: 7212-22. PMID 18448520 DOI: 10.1128/Jvi.02406-07  0.493
2008 Butler NS, Theodossis A, Webb AI, Dunstone MA, Nastovska R, Ramarathinam SH, Rossjohn J, Purcell AW, Perlman S. Structural and biological basis of CTL escape in coronavirus-infected mice. Journal of Immunology (Baltimore, Md. : 1950). 180: 3926-37. PMID 18322201 DOI: 10.4049/Jimmunol.180.6.3926  0.744
2008 Templeton SP, Perlman S. Role of IFN-gamma responsiveness in CD8 T-cell-mediated viral clearance and demyelination in coronavirus-infected mice. Journal of Neuroimmunology. 194: 18-26. PMID 18082272 DOI: 10.1016/J.Jneuroim.2007.10.030  0.809
2008 Templeton SP, Kim TS, O'Malley K, Perlman S. Maturation and localization of macrophages and microglia during infection with a neurotropic murine coronavirus. Brain Pathology (Zurich, Switzerland). 18: 40-51. PMID 17935605 DOI: 10.1111/J.1750-3639.2007.00098.X  0.826
2008 Perlman S, Butler N. Neurotropic coronavirus infections Neurotropic Viral Infections. 50-74. DOI: 10.1017/CBO9780511541728.007  0.432
2007 Bonthius DJ, Perlman S. Congenital viral infections of the brain: lessons learned from lymphocytic choriomeningitis virus in the neonatal rat. Plos Pathogens. 3: e149. PMID 18052527 DOI: 10.1371/Journal.Ppat.0030149  0.46
2007 Templeton SP, Perlman S. Pathogenesis of acute and chronic central nervous system infection with variants of mouse hepatitis virus, strain JHM. Immunologic Research. 39: 160-72. PMID 17917063 DOI: 10.1007/S12026-007-0079-Y  0.841
2007 Butler NS, Dandekar AA, Perlman S. Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus. Journal of Virology. 81: 13291-8. PMID 17913802 DOI: 10.1128/Jvi.01580-07  0.854
2007 Netland J, Ferraro D, Pewe L, Olivares H, Gallagher T, Perlman S. Enhancement of murine coronavirus replication by severe acute respiratory syndrome coronavirus protein 6 requires the N-terminal hydrophobic region but not C-terminal sorting motifs. Journal of Virology. 81: 11520-5. PMID 17670827 DOI: 10.1128/Jvi.01308-07  0.765
2007 Tangudu C, Olivares H, Netland J, Perlman S, Gallagher T. Severe acute respiratory syndrome coronavirus protein 6 accelerates murine coronavirus infections. Journal of Virology. 81: 1220-9. PMID 17108045 DOI: 10.1128/Jvi.01515-06  0.79
2007 McCray PB, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. Journal of Virology. 81: 813-21. PMID 17079315 DOI: 10.1128/Jvi.02012-06  0.8
2007 Zhou H, Perlman S. Mouse hepatitis virus does not induce Beta interferon synthesis and does not inhibit its induction by double-stranded RNA. Journal of Virology. 81: 568-74. PMID 17079305 DOI: 10.1128/Jvi.01512-06  0.582
2006 Kedzierska K, Day EB, Pi J, Heard SB, Doherty PC, Turner SJ, Perlman S. Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage. Journal of Immunology (Baltimore, Md. : 1950). 177: 6705-12. PMID 17082583 DOI: 10.4049/Jimmunol.177.10.6705  0.408
2006 Butler N, Pewe L, Trandem K, Perlman S. HCoV-OC43-induced encephalitis is in part immune-mediated. Advances in Experimental Medicine and Biology. 581: 531-4. PMID 17037592 DOI: 10.1007/978-0-387-33012-9_96  0.777
2006 Pewe L, Zhou H, Netland J, Tangadu C, Olivares H, Shi L, Look D, Gallagher T, Perlman S. A SARS-CoV-specific protein enhances virulence of an attenuated strain of mouse hepatitis virus. Advances in Experimental Medicine and Biology. 581: 493-8. PMID 17037583 DOI: 10.1007/978-0-387-33012-9_87  0.792
2006 Jia HP, Look DC, Hickey M, Shi L, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization. Advances in Experimental Medicine and Biology. 581: 479-84. PMID 17037581 DOI: 10.1007/978-0-387-33012-9_85  0.745
2006 Zhou H, Perlman S. Preferential infection of mature dendritic cells by the JHM strain of mouse hepatitis virus. Advances in Experimental Medicine and Biology. 581: 411-4. PMID 17037570 DOI: 10.1007/978-0-387-33012-9_74  0.699
2006 Anghelina D, Pewe L, Perlman S. Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis. The American Journal of Pathology. 169: 209-22. PMID 16816374 DOI: 10.2353/Ajpath.2006.051308  0.848
2006 Zhou H, Perlman S. Preferential infection of mature dendritic cells by mouse hepatitis virus strain JHM. Journal of Virology. 80: 2506-14. PMID 16474157 DOI: 10.1128/Jvi.80.5.2506-2514.2006  0.658
2006 Butler N, Pewe L, Trandem K, Perlman S. Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated. Virology. 347: 410-21. PMID 16413043 DOI: 10.1016/J.Virol.2005.11.044  0.823
2006 Perlman S, Dandekar AA. Glucocorticoid contribution to lymphopaenia and immunpathology in patients with SARS Nature Reviews Immunology. 6: 334-334. DOI: 10.1038/Nri1835-C2  0.643
2005 Perlman S, Dandekar AA. Immunopathogenesis of coronavirus infections: implications for SARS. Nature Reviews. Immunology. 5: 917-27. PMID 16322745 DOI: 10.1038/Nri1732  0.764
2005 Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. Journal of Virology. 79: 14614-21. PMID 16282461 DOI: 10.1128/Jvi.79.23.14614-14621.2005  0.772
2005 Pewe L, Zhou H, Netland J, Tangudu C, Olivares H, Shi L, Look D, Gallagher T, Perlman S. A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus. Journal of Virology. 79: 11335-42. PMID 16103185 DOI: 10.1128/Jvi.79.17.11335-11342.2005  0.82
2005 Dandekar AA, O'Malley K, Perlman S. Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus. Journal of Virology. 79: 9388-96. PMID 16014902 DOI: 10.1128/Jvi.79.15.9388-9396.2005  0.765
2005 Kim TS, Perlman S. Viral expression of CCL2 is sufficient to induce demyelination in RAG1-/- mice infected with a neurotropic coronavirus. Journal of Virology. 79: 7113-20. PMID 15890951 DOI: 10.1128/Jvi.79.11.7113-7120.2005  0.703
2005 Kim TS, Perlman S. Virus-specific antibody, in the absence of T cells, mediates demyelination in mice infected with a neurotropic coronavirus. The American Journal of Pathology. 166: 801-9. PMID 15743792 DOI: 10.1016/S0002-9440(10)62301-2  0.676
2005 Kim TS, Perlman S. The role of T cell epitopes in coronavirus infection Experimental Models of Multiple Sclerosis. 771-779. DOI: 10.1007/0-387-25518-4_42  0.612
2005 Bergmann CC, Stohlman SA, Perlman S. The role of T cells in corona-virus-induced demyelination Experimental Models of Multiple Sclerosis. 747-757. DOI: 10.1007/0-387-25518-4_40  0.468
2005 Dandekar AA, Perlman S. Axons and neurons in corona virus-induced demyelination Experimental Models of Multiple Sclerosis. 737-745. DOI: 10.1007/0-387-25518-4_39  0.724
2004 Pewe LL, Netland JM, Heard SB, Perlman S. Very diverse CD8 T cell clonotypic responses after virus infections. Journal of Immunology (Baltimore, Md. : 1950). 172: 3151-6. PMID 14978121 DOI: 10.4049/Jimmunol.172.5.3151  0.794
2004 Dandekar AA, Anghelina D, Perlman S. Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis. The American Journal of Pathology. 164: 363-9. PMID 14742242 DOI: 10.1016/S0002-9440(10)63126-4  0.837
2003 Dandekar AA, Jacobsen G, Waldschmidt TJ, Perlman S. Antibody-mediated protection against cytotoxic T-cell escape in coronavirus-induced demyelination. Journal of Virology. 77: 11867-74. PMID 14581523 DOI: 10.1128/Jvi.77.22.11867-11874.2003  0.771
2003 Ontiveros E, Kim TS, Gallagher TM, Perlman S. Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein. Journal of Virology. 77: 10260-9. PMID 12970410 DOI: 10.1128/Jvi.77.19.10260-10269.2003  0.835
2003 Kim TS, Perlman S. Protection against CTL escape and clinical disease in a murine model of virus persistence. Journal of Immunology (Baltimore, Md. : 1950). 171: 2006-13. PMID 12902505 DOI: 10.4049/Jimmunol.171.4.2006  0.727
2003 Haring JS, Perlman S. Bystander CD4 T cells do not mediate demyelination in mice infected with a neurotropic coronavirus. Journal of Neuroimmunology. 137: 42-50. PMID 12667646 DOI: 10.1016/S0165-5728(03)00041-9  0.798
2002 Dandekar AA, Perlman S. Virus-induced demyelination in nude mice is mediated by gamma delta T cells. The American Journal of Pathology. 161: 1255-63. PMID 12368199 DOI: 10.1016/S0002-9440(10)64402-1  0.785
2002 Haring JS, Pewe LL, Perlman S. Bystander CD8 T cell-mediated demyelination after viral infection of the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 169: 1550-5. PMID 12133983 DOI: 10.4049/Jimmunol.169.3.1550  0.831
2002 Pewe L, Haring J, Perlman S. CD4 T-cell-mediated demyelination is increased in the absence of gamma interferon in mice infected with mouse hepatitis virus. Journal of Virology. 76: 7329-33. PMID 12072531 DOI: 10.1128/Jvi.76.14.7329-7333.2002  0.813
2002 Pewe L, Perlman S. Cutting edge: CD8 T cell-mediated demyelination is IFN-gamma dependent in mice infected with a neurotropic coronavirus. Journal of Immunology (Baltimore, Md. : 1950). 168: 1547-51. PMID 11823480 DOI: 10.4049/Jimmunol.168.4.1547  0.505
2002 Ontiveros E, Kuo L, Masters P, Perlman S. Analysis of nonessential gene function in recombinant MHV-JHM. Gene 4 knockout recombinant virus. Advances in Experimental Medicine and Biology. 494: 83-9. PMID 11774550 DOI: 10.1007/978-1-4615-1325-4_13  0.789
2001 Wu GF, Dandekar AA, Pewe L, Perlman S. The role of CD4 and CD8 T cells in MHV-JHM-induced demyelination. Advances in Experimental Medicine and Biology. 494: 341-7. PMID 11774490 DOI: 10.1007/978-1-4615-1325-4_51  0.799
2001 Ontiveros E, Kuo L, Masters PS, Perlman S. Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS. Virology. 289: 230-8. PMID 11689046 DOI: 10.1006/Viro.2001.1167  0.813
2001 Haring J, Perlman S. Mouse hepatitis virus. Current Opinion in Microbiology. 4: 462-6. PMID 11495812 DOI: 10.1016/S1369-5274(00)00236-8  0.812
2001 Perlman S, Wu GF. Selection of and evasion from cytotoxic T cell responses in the central nervous system. Advances in Virus Research. 56: 219-42. PMID 11450301 DOI: 10.1016/S0065-3527(01)56029-7  0.707
2001 Dandekar AA, Wu GF, Pewe L, Perlman S. Axonal damage is T cell mediated and occurs concomitantly with demyelination in mice infected with a neurotropic coronavirus. Journal of Virology. 75: 6115-20. PMID 11390613 DOI: 10.1128/Jvi.75.13.6115-6120.2001  0.769
2001 Haring JS, Pewe LL, Perlman S. High-magnitude, virus-specific CD4 T-cell response in the central nervous system of coronavirus-infected mice. Journal of Virology. 75: 3043-7. PMID 11222733 DOI: 10.1128/Jvi.75.6.3043-3047.2001  0.818
2001 Kolb AF, Pewe L, Webster J, Perlman S, Whitelaw CB, Siddell SG. Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis. Journal of Virology. 75: 2803-9. PMID 11222704 DOI: 10.1128/Jvi.75.6.2803-2809.2001  0.443
2000 Wang G, Deering C, Macke M, Shao J, Burns R, Blau DM, Holmes KV, Davidson BL, Perlman S, McCray PB. Human coronavirus 229E infects polarized airway epithelia from the apical surface. Journal of Virology. 74: 9234-9. PMID 10982370 DOI: 10.1128/Jvi.74.19.9234-9239.2000  0.398
2000 Wu GF, Dandekar AA, Pewe L, Perlman S. CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. Journal of Immunology (Baltimore, Md. : 1950). 165: 2278-86. PMID 10925317 DOI: 10.4049/Jimmunol.165.4.2278  0.8
2000 Wu GF, Pewe L, Perlman S. Coronavirus-induced demyelination occurs in the absence of inducible nitric oxide synthase. Journal of Virology. 74: 7683-6. PMID 10906226 DOI: 10.1128/Jvi.74.16.7683-7686.2000  0.632
1999 Rakasz E, Mueller A, Perlman S, Lynch RG. Gammadelta T cell response induced by vaginal Herpes simplex 2 infection. Immunology Letters. 70: 89-93. PMID 10569697 DOI: 10.1016/S0165-2478(99)00132-7  0.532
1999 Wu GF, Perlman S. Macrophage infiltration, but not apoptosis, is correlated with immune-mediated demyelination following murine infection with a neurotropic coronavirus. Journal of Virology. 73: 8771-80. PMID 10482631 DOI: 10.1128/Jvi.73.10.8771-8780.1999  0.671
1999 Pewe L, Perlman S. Immune response to the immunodominant epitope of mouse hepatitis virus is polyclonal, but functionally monospecific in C57BI/6 mice Virology. 255: 106-116. PMID 10049826 DOI: 10.1006/Viro.1998.9576  0.528
1999 Xue S, Sun N, Van Rooijen N, Perlman S. Depletion of Blood-Borne Macrophages Does Not Reduce Demyelination in Mice Infected with a Neurotropic Coronavirus Journal of Virology. 73: 6327-6334. DOI: 10.1128/Jvi.73.8.6327-6334.1999  0.445
1998 Perlman S, Pewe L. Role of CTL mutants in demyelination induced by mouse hepatitis virus, strain JHM Advances in Experimental Medicine and Biology. 440: 515-519. PMID 9782323 DOI: 10.1007/978-1-4615-5331-1_66  0.507
1998 Perlman S. Pathogenesis of coronavirus-induced infections: Review of pathological and immunological aspects Advances in Experimental Medicine and Biology. 440: 503-513. PMID 9782322  0.402
1998 LaBrecque FD, LaBrecque DR, Klinzman D, Perlman S, Cederna JB, Winokur PL, Han JQ, Stapleton JT. Recombinant hepatitis A virus antigen: Improved production and utility in diagnostic immunoassays Journal of Clinical Microbiology. 36: 2014-2018. PMID 9650953 DOI: 10.1128/Jcm.36.7.2014-2018.1998  0.307
1998 Pewe L, Xue S, Perlman S. Infection with Cytotoxic T-Lymphocyte Escape Mutants Results in Increased Mortality and Growth Retardation in Mice Infected with a Neurotropic Coronavirus Journal of Virology. 72: 5912-5918. DOI: 10.1128/Jvi.72.7.5912-5918.1998  0.572
1998 Perlman S. Pathogenesis of Coronavirus-Induced Infections Advances in Experimental Medicine and Biology. 440: 503-513. DOI: 10.1007/978-1-4615-5331-1_65  0.501
1997 Xue S, Perlman S. Antigen specificity of CD4 T cell response in the central nervous system of mice infected with mouse hepatitis virus Virology. 238: 68-78. PMID 9375010 DOI: 10.1006/Viro.1997.8819  0.547
1997 Grzybicki DM, Kwack K, Perlman S, Murphy SP. Nitric oxide synthase Type II expression by different cell types in MHV-JHM encephalitis suggests distinct roles for nitric oxide in acute versus persistent virus infection Journal of Neuroimmunology. 73: 15-27. PMID 9058755 DOI: 10.1016/S0165-5728(96)00159-2  0.46
1997 Pewe L, Xue S, Perlman S. Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus. Journal of Virology. 71: 7640-7647. DOI: 10.1128/Jvi.71.10.7640-7647.1997  0.539
1996 Pewe L, Wu GF, Barnett EM, Castro RF, Perlman S. Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. Immunity. 5: 253-62. PMID 8808680 DOI: 10.1016/S1074-7613(00)80320-9  0.689
1996 Castro RF, Perlman S. Differential antigen recognition by T cells from the spleen and central nervous system of coronavirus-infected mice. Virology. 222: 247-51. PMID 8806504 DOI: 10.1006/Viro.1996.0415  0.493
1996 Sun N, Cassell MD, Perlman S. Anterograde, transneuronal transport of herpes simplex virus type 1 strain H129 in the murine visual system. Journal of Virology. 70: 5405-13. PMID 8764051 DOI: 10.1128/Jvi.70.8.5405-5413.1996  0.39
1995 Xue S, Jaszewski A, Perlman S. Identification of a CD4+ T cell epitope within the M protein of a neurotropic coronavirus Virology. 208: 173-179. PMID 11831697 DOI: 10.1006/Viro.1995.1140  0.503
1995 Perlman S, Sun N, Barnett EM. Spread of MHV-JHM from nasal cavity to white matter of spinal cord. Transneuronal movement and involvement of astrocytes. Advances in Experimental Medicine and Biology. 380: 73-8. PMID 8830549 DOI: 10.1007/978-1-4615-1899-0_10  0.414
1995 Sun N, Perlman S. Spread of a neurotropic coronavirus to spinal cord white matter via neurons and astrocytes Journal of Virology. 69: 633-641. PMID 7815526 DOI: 10.1128/Jvi.69.2.633-641.1995  0.389
1995 Castro RF, Perlman S. CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity. Journal of Virology. 69: 8127-31. PMID 7494335 DOI: 10.1128/Jvi.69.12.8127-8131.1995  0.517
1995 Sun N, Grzybicki D, Castro RF, Murphy S, Perlman S. Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus. Virology. 213: 482-93. PMID 7491773 DOI: 10.1006/Viro.1995.0021  0.461
1995 Barnett E, Evans G, Sun N, Perlman S, Cassell M. Anterograde tracing of trigeminal afferent pathways from the murine tooth pulp to cortex using herpes simplex virus type 1 The Journal of Neuroscience. 15: 2972-2984. DOI: 10.1523/Jneurosci.15-04-02972.1995  0.366
1994 Chung S, Li C, Fung LS, Crow A, Gorczynski R, Cole E, Perlman S, Leibowitz J, Levy G. Role of macrophage procoagulant activity in mouse hepatitis virus (MHV) infection: studies using T cell MHV-3 clones and monoclonal antibody 3D4.3. Advances in Experimental Medicine and Biology. 342: 377-84. PMID 8209757 DOI: 10.1007/978-1-4615-2996-5_58  0.463
1994 Gallagher TM, Buchmeier MJ, Perlman S. Dissemination of MHV4 (strain JHM) infection does not require specific coronavirus receptors Advances in Experimental Medicine and Biology. 342: 279-284. PMID 8209743 DOI: 10.1007/978-1-4615-2996-5_43  0.477
1994 Oleszak EL, Perlman S, Parr R, Collisson EW, Leibowitz JL. Molecular mimicry between S peplomer proteins of coronaviruses (MHV, BCV, TGEV and IBV) and Fc receptor Advances in Experimental Medicine and Biology. 342: 183-188. PMID 8209728 DOI: 10.1007/978-1-4615-2996-5_29  0.349
1994 Castro RF, Evans GD, Jaszewski A, Perlman S. Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells. Virology. 200: 733-43. PMID 8178457 DOI: 10.1006/Viro.1994.1237  0.506
1994 Barnett EM, Jacobsen G, Evans G, Cassell M, Perlman S. Herpes simplex encephalitis in the temporal cortex and limbic system after trigeminal nerve inoculation. The Journal of Infectious Diseases. 169: 782-6. PMID 8133092 DOI: 10.1093/Infdis/169.4.782  0.413
1994 Perlman S, Barnett E, Jacobsen G. Mouse hepatitis virus and herpes simplex virus move along different CNS pathways Advances in Experimental Medicine and Biology. 342: 313-318. PMID 7516106 DOI: 10.1007/978-1-4615-2996-5_48  0.46
1993 Barnett EM, Perlman S. The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM Virology. 194: 185-191. PMID 8386871 DOI: 10.1006/Viro.1993.1248  0.34
1993 Barnett EM, Cassell MD, Perlman S. Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb. Neuroscience. 57: 1007-25. PMID 8309541 DOI: 10.1016/0306-4522(93)90045-H  0.473
1992 Gallagher TM, Buchmeier MJ, Perlman S. Cell receptor-independent infection by a neurotropic murine coronavirus Virology. 191: 517-522. PMID 1413526 DOI: 10.1016/0042-6822(92)90223-C  0.484
1992 Mobley J, Evans G, Dailey MO, Perlman S. Immune response to a murine coronavirus: identification of a homing receptor-negative CD4+ T cell subset that responds to viral glycoproteins. Virology. 187: 443-52. PMID 1347668 DOI: 10.1016/0042-6822(92)90446-V  0.559
1992 Oleszak EL, Perlman S, Leibowitz JL. MHV S peplomer protein expressed by a recombinant vaccinia virus vector exhibits IgG Fc-receptor activity Virology. 186: 122-132. PMID 1309271 DOI: 10.1016/0042-6822(92)90066-X  0.396
1990 Perlman S, Jacobsen G, Olson AL, Afifi A. Identification of the spinal cord as a major site of persistence during during chronic infection with a murine coronavirus Virology. 175: 418-426. PMID 2158180 DOI: 10.1016/0042-6822(90)90426-R  0.401
1990 Jacobsen G, Perlman S. Localization of virus and antibody response in mice infected persistently with MHV-JHM Advances in Experimental Medicine and Biology. 276: 573-578. PMID 1966451 DOI: 10.1007/978-1-4684-5823-7_79  0.453
1990 Perlman S, Evans G, Afifi A. Effect of olfactory bulb ablation on spread of a neurotropic coronavirus into the mouse brain Journal of Experimental Medicine. 172: 1127-1132. PMID 1698910 DOI: 10.1084/Jem.172.4.1127  0.34
1989 Perlman S, Jacobsen G, Afifi A. Spread of a neurotropic murine coronavirus into the CNS via the trigeminal and olfactory nerves Virology. 170: 556-560. PMID 2543129 DOI: 10.1016/0042-6822(89)90446-7  0.459
1988 Perlman S, Jacobsen G, Moore S. Regional localization of virus in the central nervous system of mice persistently infected with murine coronavirus JHM Virology. 166: 328-338. PMID 2845647 DOI: 10.1016/0042-6822(88)90503-X  0.459
1987 Denison M, Perlman S. Identification of putative polymerase gene product in cells infected with murine coronavirus A59 Virology. 157: 565-568. PMID 3029990 DOI: 10.1016/0042-6822(87)90303-5  0.412
1987 Bale JF, O'Neil ME, Giller R, Perlman S, Koszinowski U. Murine cytomegalovirus genomic material in marrow cells: relation to altered leukocyte counts during sublethal infection of mice. The Journal of Infectious Diseases. 155: 207-12. PMID 3027192 DOI: 10.1093/Infdis/155.2.207  0.431
1987 Perlman S, Schelper R, Bolger E, Ries D. Late onset, symptomatic, demyelinating encephalomyelitis in mice infected with MHV-JHM in the presence of maternal antibody. Microbial Pathogenesis. 2: 185-94. PMID 2853274 DOI: 10.1016/0882-4010(87)90020-9  0.469
1987 Perlman S, Ries D. The Astrocyte Is a Target Cell in Mice Persistently Infected With Mouse Hepatitis Virus, Strain JHM Microbial Pathogenesis. 3: 309-314. PMID 2849022 DOI: 10.1016/0882-4010(87)90064-7  0.51
1987 Perlman S, Schelper R, Ries D. Maternal antibody-modulated MHV-JHM infection in C57BL/6 and BALB/c mice. Advances in Experimental Medicine and Biology. 218: 297-305. PMID 2829543 DOI: 10.1007/978-1-4684-1280-2_39  0.428
1987 Denison M, Perlman S. Translation and processing of MHV-A59 virion RNA in reticulocyte lysates and infected cells Advances in Experimental Medicine and Biology. 218: 155-156. PMID 2829524 DOI: 10.1007/978-1-4684-1280-2_18  0.342
1986 Perlman S, Ries D, Bolger E, Chang LJ, Stoltzfus CM. MHV nucleocapsid synthesis in the presence of cycloheximide and accumulation of negative strand MHV RNA. Virus Research. 6: 261-72. PMID 3033933 DOI: 10.1016/0168-1702(86)90074-2  0.319
1986 Denison MR, Perlman S. Translation and processing of mouse hepatitis virus virion RNA in a cell-free system Journal of Virology. 60: 12-18. PMID 3018279 DOI: 10.1128/Jvi.60.1.12-18.1986  0.322
1985 Broderick A, Perlman S, Dietz F. Pseudomonas bursitis: Inoculation from a catfish Pediatric Infectious Disease. 4: 693-694. PMID 4080588 DOI: 10.1097/00006454-198511000-00022  0.313
1985 Murph JR, Bale JF, Perlman S, Swack NS, Smith FG. 566 THE PREVALENCE OF CYTOMEGALOVIRUS INFECTION IN MIDWEST DAY CAKE CENTER Pediatric Research. 19: 205A-205A. DOI: 10.1203/00006450-198504000-00596  0.341
1972 Perlman S, Hirsch M, Penman S. Utilization of messenger in adenovirus-2-infected cells at normal and elevated temperatures. Nature: New Biology. 238: 143-4. PMID 4506191 DOI: 10.1038/Newbio238143A0  0.319
Show low-probability matches.