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Jeffrey Whitsett - Publications

Affiliations: 
Cell & Molecular Biology University of Cincinnati, Cincinnati, OH 
Area:
Genetics, Cell Biology, Molecular Biology
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368 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA. PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function. Biorxiv : the Preprint Server For Biology. PMID 38187557 DOI: 10.1101/2023.12.20.570481  0.435
2023 Guo M, Morley MP, Jiang C, Wu Y, Li G, Du Y, Zhao S, Wagner A, Cakar AC, Kouril M, Jin K, Gaddis N, Kitzmiller JA, Stewart K, Basil MC, ... ... Whitsett JA, et al. Guided construction of single cell reference for human and mouse lung. Nature Communications. 14: 4566. PMID 37516747 DOI: 10.1038/s41467-023-40173-5  0.401
2023 Guo M, Wikenheiser-Brokamp KA, Kitzmiller JA, Jiang C, Wang G, Wang A, Preissl S, Hou X, Buchanan J, Karolak JA, Miao Y, Frank DB, Zacharias WJ, Sun X, Xu Y, ... ... Whitsett JA, et al. Single Cell Multiomics Identifies Cells and Genetic Networks Underlying Alveolar Capillary Dysplasia. American Journal of Respiratory and Critical Care Medicine. PMID 37463497 DOI: 10.1164/rccm.202210-2015OC  0.435
2023 Sikkema L, Ramírez-Suástegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, Markov NS, Zaragosi LE, Ji Y, Ansari M, Arguel MJ, Apperloo L, Banchero M, Bécavin C, Berg M, ... ... Whitsett J, et al. An integrated cell atlas of the lung in health and disease. Nature Medicine. PMID 37291214 DOI: 10.1038/s41591-023-02327-2  0.394
2023 Olatoke T, Wagner A, Astrinidis A, Zhang EY, Guo M, Zhang AG, Mattam U, Kopras EJ, Gupta N, Smith EP, Karbowniczek M, Markiewski MM, Wikenheiser-Brokamp KA, Whitsett JA, McCormack FX, et al. Single-cell multiomic analysis identifies a HOX-PBX gene network regulating the survival of lymphangioleiomyomatosis cells. Science Advances. 9: eadf8549. PMID 37163604 DOI: 10.1126/sciadv.adf8549  0.397
2022 Toth A, Steinmeyer S, Kannan P, Gray J, Jackson CM, Mukherjee S, Demmert M, Sheak JR, Benson D, Kitzmiller J, Wayman JA, Presicce P, Cates C, Rubin R, Chetal K, ... ... Whitsett JA, et al. Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates. Science Translational Medicine. 14: eabl8574. PMID 35353543 DOI: 10.1126/scitranslmed.abl8574  0.346
2021 Clair G, Bramer LM, Misra R, McGraw MD, Bhattacharya S, Kitzmiller JA, Feng S, Danna VG, Bandyopadhyay G, Bhotika H, Huyck HL, Deutsch GH, Mariani TJ, Carson J, Whitsett JA, et al. Proteomic Analysis of Human Lung Development. American Journal of Respiratory and Critical Care Medicine. PMID 34752721 DOI: 10.1164/rccm.202008-3303OC  0.361
2021 Gokey JJ, Snowball J, Sridharan A, Sudha P, Kitzmiller JA, Xu Y, Whitsett JA. YAP regulates alveolar epithelial cell differentiation and via NFIB/KLF5/NKX2-1. Iscience. 24: 102967. PMID 34466790 DOI: 10.1016/j.isci.2021.102967  0.449
2021 Kolesnichenko OA, Whitsett JA, Kalin TV, Kalinichenko VV. Therapeutic Potential of Endothelial Progenitor Cells in Pulmonary Diseases. American Journal of Respiratory Cell and Molecular Biology. PMID 34293272 DOI: 10.1165/rcmb.2021-0152TR  0.342
2021 Kolesnichenko OA, Whitsett JA, Kalin TV, Kalinichenko VV. Therapeutic Potential of Endothelial Progenitor Cells in Pulmonary Diseases. American Journal of Respiratory Cell and Molecular Biology. PMID 34293272 DOI: 10.1165/rcmb.2021-0152TR  0.342
2021 Rindler TN, Brown KM, Stockman CA, van Lieshout LP, Martin EP, Weaver TE, Zacharias WJ, Wootton SK, Whitsett JA, Bridges JP. Efficient Transduction of Alveolar Type 2 Cells with Adeno-associated Virus for the Study of Lung Regeneration. American Journal of Respiratory Cell and Molecular Biology. 65: 118-121. PMID 34241584 DOI: 10.1165/rcmb.2021-0049LE  0.34
2021 Sun YL, Hurley K, Villacorta-Martin C, Huang J, Hinds A, Gopalan K, Caballero IS, Russo SJ, Kitzmiller JA, Whitsett JA, Beers MF, Kotton DN. Heterogeneity in Human iPSC-derived Alveolar Epithelial Type II Cells Revealed with ABCA3/SFTPC Reporters. American Journal of Respiratory Cell and Molecular Biology. PMID 34101541 DOI: 10.1165/rcmb.2020-0259OC  0.4
2021 Jiang M, Fang Y, Li Y, Huang H, Wei Z, Gao X, Sung HK, Hu J, Qiang L, Ruan J, Chen Q, Jiang D, Whitsett JA, Ai X, Que J. VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway. Developmental Cell. PMID 34010630 DOI: 10.1016/j.devcel.2021.04.027  0.364
2021 He H, Snowball J, Sun F, Na CL, Whitsett JA. IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis. Jci Insight. PMID 33591952 DOI: 10.1172/jci.insight.144863  0.416
2021 Li E, Ustiyan V, Wen B, Kalin GT, Whitsett JA, Kalin TV, Kalinichenko VV. Blastocyst Complementation Reveals that NKX2-1 Establishes the Proximal-Peripheral Boundary of the Airway Epithelium. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 33428297 DOI: 10.1002/dvdy.298  0.339
2021 Du Y, Ouyang W, Kitzmiller JA, Guo M, Zhao S, Whitsett JA, Xu Y. Lung Gene Expression Analysis Web Portal Version 3: Lung-at-a-Glance. American Journal of Respiratory Cell and Molecular Biology. 64: 146-149. PMID 33385216 DOI: 10.1165/rcmb.2020-0308LE  0.38
2020 Wen B, Li E, Ustiyan V, Wang G, Guo M, Na CL, Kalin GT, Galvan V, Xu Y, Weaver TE, Kalin TV, Whitsett JA, Kalinichenko VV. Generation of Lung and Thyroid Tissues from Embryonic Stem Cells using Blastocyst Complementation. American Journal of Respiratory and Critical Care Medicine. PMID 32877203 DOI: 10.1164/rccm.201909-1836OC  0.4
2020 Kang MH, van Lieshout LP, Xu L, Domm JM, Vadivel A, Renesme L, Mühlfeld C, Hurskainen M, Mižíková I, Pei Y, van Vloten JP, Thomas SP, Milazzo C, Cyr-Depauw C, Whitsett JA, et al. A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency. Nature Communications. 11: 3929. PMID 32764559 DOI: 10.1038/s41467-020-17577-8  0.391
2020 Guo M, Yu JJ, Perl AK, Wikenheiser-Brokamp KA, Riccetti M, Zhang EY, Sudha P, Adam M, Potter A, Kopras EJ, Giannikou K, Potter SS, Sherman S, Hammes SR, Kwiatkowski DJ, ... Whitsett JA, et al. Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American Journal of Respiratory and Critical Care Medicine. PMID 32603599 DOI: 10.1164/rccm.201912-2445OC  0.35
2020 Bridges JP, Sudha P, Lipps D, Wagner A, Guo M, Du Y, Brown K, Filuta A, Kitzmiller JA, Stockman C, Chen X, Weirauch MT, Jobe AH, Whitsett JA, Xu Y. Glucocorticoid Regulates Mesenchymal Cell Differentiation Required for Perinatal Lung Morphogenesis and Function. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32460513 DOI: 10.1152/ajplung.00459.2019  0.46
2020 Basil MC, Katzen J, Engler AE, Guo M, Herriges MJ, Kathiriya JJ, Windmueller R, Ysasi AB, Zacharias WJ, Chapman HA, Kotton DN, Rock JR, Snoeck HW, Vunjak-Novakovic G, Whitsett JA, et al. The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. Cell Stem Cell. 26: 482-502. PMID 32243808 DOI: 10.1016/J.Stem.2020.03.009  0.365
2019 Ren X, Ustiyan V, Guo M, Wang G, Bolte C, Zhang Y, Xu Y, Whitsett JA, Kalin TV, Kalinichenko VV. Postnatal Alveologenesis Depends on FOXF1 Signaling in c-KIT Endothelial Progenitor Cells. American Journal of Respiratory and Critical Care Medicine. PMID 31233341 DOI: 10.1164/Rccm.201812-2312Oc  0.377
2019 Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, et al. The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental Cell. PMID 30930166 DOI: 10.1016/J.Devcel.2019.03.001  0.388
2019 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y. Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nature Communications. 10: 37. PMID 30604742 DOI: 10.1038/s41467-018-07770-1  0.411
2019 Whitsett JA, Kalin TV, Xu Y, Kalinichenko VV. Building and Regenerating the Lung Cell by Cell. Physiological Reviews. 99: 513-554. PMID 30427276 DOI: 10.1152/physrev.00001.2018  0.475
2019 Wandel M, Davies E, Kelly J, Holgate S, Whitsett J, Davies D, Haitchi H. S130 Maternal allergic airway inflammation during pregnancy alters offspring’s airway hyperresponsiveness dependent on muscarinic receptor and adam33 mediated mechanisms Thorax. 74. DOI: 10.1136/Thorax-2019-Btsabstracts2019.136  0.434
2018 Whitsett JA. Airway Epithelial Differentiation and Mucociliary Clearance. Annals of the American Thoracic Society. 15: S143-S148. PMID 30431340 DOI: 10.1513/AnnalsATS.201802-128AW  0.368
2018 Kyle JE, Clair G, Bandyopadhyay G, Misra RS, Zink EM, Bloodsworth KJ, Shukla AK, Du Y, Lillis J, Myers JR, Ashton J, Bushnell T, Cochran M, Deutsch G, Baker ES, ... ... Whitsett JA, et al. Cell type-resolved human lung lipidome reveals cellular cooperation in lung function. Scientific Reports. 8: 13455. PMID 30194354 DOI: 10.1038/S41598-018-31640-X  0.377
2018 Gokey JJ, Snowball J, Sridharan A, Speth JP, Black KE, Hariri LP, Perl AT, Xu Y, Whitsett JA. MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation. Jci Insight. 3. PMID 30185671 DOI: 10.1172/Jci.Insight.122490  0.467
2018 Bandyopadhyay G, Huyck HL, Misra RS, Bhattacharya S, Wang Q, Mereness J, Lillis JA, Myers JR, Ashton J, Bushnell T, Cochran M, Holden-Wiltse J, Katzman P, Deutsch GH, Whitsett JA, et al. Dissociation, Cellular Isolation and Initial Molecular Characterization of Neonatal and Pediatric Human Lung Tissues. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29975103 DOI: 10.1152/ajplung.00041.2018  0.415
2018 Gokey JJ, Sridharan A, Xu Y, Green J, Carraro G, Stripp BR, Perl AT, Whitsett JA. Active epithelial Hippo signaling in idiopathic pulmonary fibrosis. Jci Insight. 3. PMID 29563341 DOI: 10.1172/Jci.Insight.98738  0.359
2018 Moghieb A, Clair G, Mitchell H, Kitzmiller JA, Zink EM, Kim YM, Petyuk V, Shukla AK, Moore RJ, Metz TO, Carson JP, McDermott JE, Corley RA, Whitsett JA, Ansong C. Time-resolved Proteome Profiling of Normal Lung Development. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29516783 DOI: 10.1152/Ajplung.00316.2017  0.399
2018 Ding J, Aronow B, Kaminski N, Kitzmiller J, Whitsett J, Bar-Joseph Z. Reconstructing differentiation networks and their regulation from time series single cell expression data. Genome Research. PMID 29317474 DOI: 10.1101/Gr.225979.117  0.317
2018 Bolte C, Whitsett JA, Kalin TV, Kalinichenko VV. Transcription Factors Regulating Embryonic Development of Pulmonary Vasculature. Advances in Anatomy, Embryology, and Cell Biology. 228: 1-20. PMID 29288383 DOI: 10.1007/978-3-319-68483-3_1  0.469
2018 Davies E, Kelly J, Whitsett J, Davies D, Haitchi HM. Corticosteroid-resistant neutrophilic airway inflammation and hyperresponsiveness caused by IL-13 European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa973  0.383
2018 Davies E, Wandel M, Kelly J, Holgate S, Whitsett J, Davies D, Haitchi H. S29 The effect of soluble ADAM33 on allergic airway inflammation in early life is age dependent Thorax. 73. DOI: 10.1136/Thorax-2018-212555.35  0.449
2018 Wandel M, Davies E, Kelly J, Holgate S, Whitsett J, Davies D, Haitchi H. S28 Adam33 knock-out is protective against post-natal airway hyperresponsiveness caused by maternal allergy Thorax. 73. DOI: 10.1136/Thorax-2018-212555.34  0.476
2018 Kelly J, Davies E, Bell J, Holgate S, Zu Y, Whitsett J, Davies D, Haitchi H. S27 Adam33 knockout mice have an altered metabolic transcriptional profile in response to house dust mite when compared to wild type mice Thorax. 73. DOI: 10.1136/Thorax-2018-212555.33  0.429
2017 Milewski D, Balli D, Ustiyan V, Le T, Dienemann H, Warth A, Breuhahn K, Whitsett JA, Kalinichenko VV, Kalin TV. FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas. Plos Genetics. 13: e1007097. PMID 29267283 DOI: 10.1371/journal.pgen.1007097  0.429
2017 Rindler TN, Stockman CA, Filuta AL, Brown KM, Snowball JM, Zhou W, Veldhuizen R, Zink EM, Dautel SE, Clair G, Ansong C, Xu Y, Bridges JP, Whitsett JA. Alveolar injury and regeneration following deletion of ABCA3. Jci Insight. 2. PMID 29263307 DOI: 10.1172/Jci.Insight.97381  0.461
2017 Tang X, Snowball JM, Xu Y, Na CL, Weaver TE, Clair G, Kyle JE, Zink EM, Ansong C, Wei W, Huang M, Lin X, Whitsett JA. EMC3 coordinates surfactant protein and lipid homeostasis required for respiration. The Journal of Clinical Investigation. PMID 29083321 DOI: 10.1172/JCI94152  0.372
2017 Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, ... ... Whitsett JA, et al. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. PMID 28965766 DOI: 10.1016/J.Stem.2017.08.014  0.405
2017 Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, Pryhuber GS, Warburton D, Whitsett JA, Palmer SM, Ambalavanan N, et al. LungMAP: The Molecular Atlas of Lung Development Program. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00139.2017. PMID 28798251 DOI: 10.1152/Ajplung.00139.2017  0.363
2017 Brown K, Filuta A, Ludwig MG, Seuwen K, Jaros J, Vidal S, Arora K, Naren AP, Kandasamy K, Parthasarathi K, Offermanns S, Mason RJ, Miller WE, Whitsett JA, Bridges JP. Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling. Jci Insight. 2. PMID 28570277 DOI: 10.1172/Jci.Insight.93700  0.377
2017 Sun L, Ren X, Wang IC, Pradhan A, Zhang Y, Flood HM, Han B, Whitsett JA, Kalin TV, Kalinichenko VV. The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice. Science Signaling. 10. PMID 28420758 DOI: 10.1126/scisignal.aai8583  0.382
2017 Gray J, Oehrle K, Worthen G, Alenghat T, Whitsett J, Deshmukh H. Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection. Science Translational Medicine. 9. PMID 28179507 DOI: 10.1126/Scitranslmed.Aaf9412  0.445
2017 Du Y, Kitzmiller JA, Sridharan A, Perl AK, Bridges JP, Misra RS, Pryhuber GS, Mariani TJ, Bhattacharya S, Guo M, Potter SS, Dexheimer P, Aronow B, Jobe AH, Whitsett JA, et al. Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development. Thorax. PMID 28070014 DOI: 10.1136/thoraxjnl-2016-209598  0.419
2017 Kelly J, Davies E, Holgate S, Xu X, Whitsett J, Davies D, Haitchi H. S89 Soluble adam33 augments the pulmonary immune response promoting allergic airway sensitivity Thorax. 72. DOI: 10.1136/Thoraxjnl-2017-210983.95  0.481
2017 Davies E, Kelly J, Whitsett J, Holgate S, Davies D, Haitchi H. S85 Corticosteroid-resistant neutrophilic airway inflammation and hyperresponsiveness caused by il-13 Thorax. 72. DOI: 10.1136/Thoraxjnl-2017-210983.91  0.377
2016 Guo M, Bao EL, Wagner M, Whitsett JA, Xu Y. SLICE: determining cell differentiation and lineage based on single cell entropy. Nucleic Acids Research. PMID 27998929 DOI: 10.1093/nar/gkw1278  0.311
2016 Xu Y, Mizuno T, Sridharan A, Du Y, Guo M, Tang J, Wikenheiser-Brokamp KA, Perl AT, Funari VA, Gokey JJ, Stripp BR, Whitsett JA. Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. Jci Insight. 1: e90558. PMID 27942595 DOI: 10.1172/Jci.Insight.90558  0.452
2016 Vummidi Giridhar P, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA. Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens. Journal of Immunology (Baltimore, Md. : 1950). PMID 27794000 DOI: 10.4049/jimmunol.1600926  0.365
2016 Whitsett JA, Morrisey EE. INFLAMMATION. Modulating pulmonary inflammation. Science (New York, N.Y.). 351: 662-3. PMID 26912844 DOI: 10.1126/Science.Aaf1429  0.399
2016 Ustiyan V, Zhang Y, Perl AT, Whitsett JA, Kalin TV, Kalinichenko VV. β-Catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 26869074 DOI: 10.1002/dvdy.24393  0.441
2015 Wakata K, Tsuchiya T, Tomoshige K, Takagi K, Yamasaki N, Matsumoto K, Miyazaki T, Nanashima A, Whitsett JA, Maeda Y, Nagayasu T. A favourable prognostic marker for EGFR mutant non-small cell lung cancer: immunohistochemical analysis of MUC5B. Bmj Open. 5: e008366. PMID 26224019 DOI: 10.1136/bmjopen-2015-008366  0.305
2015 Du Y, Guo M, Whitsett JA, Xu Y. 'LungGENS': a web-based tool for mapping single-cell gene expression in the developing lung. Thorax. PMID 26130332 DOI: 10.1136/thoraxjnl-2015-207035  0.358
2015 Snowball J, Ambalavanan M, Whitsett J, Sinner D. Endodermal Wnt signaling is required for tracheal cartilage formation. Developmental Biology. 405: 56-70. PMID 26093309 DOI: 10.1016/J.Ydbio.2015.06.009  0.342
2015 Whitsett JA, Weaver TE. Alveolar development and disease. American Journal of Respiratory Cell and Molecular Biology. 53: 1-7. PMID 25932959 DOI: 10.1165/rcmb.2015-0128PS  0.383
2015 Rajavelu P, Chen G, Xu Y, Kitzmiller JA, Korfhagen TR, Whitsett JA. Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation. The Journal of Clinical Investigation. 125: 2021-31. PMID 25866971 DOI: 10.1172/JCI79422  0.436
2015 Whitsett JA, Wert SE, Weaver TE. Diseases of pulmonary surfactant homeostasis. Annual Review of Pathology. 10: 371-93. PMID 25621661 DOI: 10.1146/annurev-pathol-012513-104644  0.365
2015 Whitsett JA, Alenghat T. Respiratory epithelial cells orchestrate pulmonary innate immunity. Nature Immunology. 16: 27-35. PMID 25521682 DOI: 10.1038/Ni.3045  0.369
2015 Lange AW, Sridharan A, Xu Y, Stripp BR, Perl AK, Whitsett JA. Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung. Journal of Molecular Cell Biology. 7: 35-47. PMID 25480985 DOI: 10.1093/Jmcb/Mju046  0.456
2015 Zhou J, Qu Z, Yan S, Sun F, Whitsett JA, Shapiro SD, Xiao G. Differential roles of STAT3 in the initiation and growth of lung cancer. Oncogene. 34: 3804-14. PMID 25284582 DOI: 10.1038/Onc.2014.318  0.376
2015 Xia H, Ren X, Bolte CS, Ustiyan V, Zhang Y, Shah TA, Kalin TV, Whitsett JA, Kalinichenko VV. Foxm1 regulates resolution of hyperoxic lung injury in newborns. American Journal of Respiratory Cell and Molecular Biology. 52: 611-21. PMID 25275225 DOI: 10.1165/Rcmb.2014-0091Oc  0.446
2015 Davies E, Whitsett J, Davies D, Haitchi H. S128 Soluble ADAM33 Causes Airway Remodelling To Promote Allergic Airway Inflammation Thorax. 70: A73.1-A73. DOI: 10.1136/Thoraxjnl-2015-207770.134  0.421
2014 McCauley HA, Liu CY, Attia AC, Wikenheiser-Brokamp KA, Zhang Y, Whitsett JA, Guasch G. TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium. Development (Cambridge, England). 141: 4628-39. PMID 25377551 DOI: 10.1242/dev.117804  0.352
2014 Hogan BL, Barkauskas CE, Chapman HA, Epstein JA, Jain R, Hsia CC, Niklason L, Calle E, Le A, Randell SH, Rock J, Snitow M, Krummel M, Stripp BR, Vu T, ... ... Whitsett JA, et al. Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell. 15: 123-38. PMID 25105578 DOI: 10.1016/J.Stem.2014.07.012  0.332
2014 Whitsett JA. The molecular era of surfactant biology. Neonatology. 105: 337-43. PMID 24931326 DOI: 10.1159/000360649  0.362
2014 Bridges JP, Schehr A, Wang Y, Huo L, Besnard V, Ikegami M, Whitsett JA, Xu Y. Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation. Plos One. 9: e91376. PMID 24806461 DOI: 10.1371/journal.pone.0091376  0.447
2014 Lange AW, Haitchi HM, LeCras TD, Sridharan A, Xu Y, Wert SE, James J, Udell N, Thurner PJ, Whitsett JA. Sox17 is required for normal pulmonary vascular morphogenesis. Developmental Biology. 387: 109-20. PMID 24418654 DOI: 10.1016/j.ydbio.2013.11.018  0.345
2014 Chen G, Korfhagen TR, Karp CL, Impey S, Xu Y, Randell SH, Kitzmiller J, Maeda Y, Haitchi HM, Sridharan A, Senft AP, Whitsett JA. Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity. American Journal of Respiratory and Critical Care Medicine. 189: 301-13. PMID 24392884 DOI: 10.1164/Rccm.201306-1181Oc  0.412
2013 Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, ... ... Whitsett JA, et al. Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer. Plos One. 8: e71093. PMID 23976985 DOI: 10.1371/journal.pone.0071093  0.375
2013 Tang X, Liu XJ, Tian C, Su Q, Lei Y, Wu Q, He Y, Whitsett JA, Luo F. Foxa2 regulates leukotrienes to inhibit Th2-mediated pulmonary inflammation. American Journal of Respiratory Cell and Molecular Biology. 49: 960-70. PMID 23822876 DOI: 10.1165/rcmb.2013-0122OC  0.478
2013 Marko CK, Menon BB, Chen G, Whitsett JA, Clevers H, Gipson IK. Spdef null mice lack conjunctival goblet cells and provide a model of dry eye. The American Journal of Pathology. 183: 35-48. PMID 23665202 DOI: 10.1016/J.Ajpath.2013.03.017  0.338
2013 Morrisey EE, Cardoso WV, Lane RH, Rabinovitch M, Abman SH, Ai X, Albertine KH, Bland RD, Chapman HA, Checkley W, Epstein JA, Kintner CR, Kumar M, Minoo P, Mariani TJ, ... ... Whitsett JA, et al. Molecular determinants of lung development. Annals of the American Thoracic Society. 10: S12-6. PMID 23607856 DOI: 10.1513/Annalsats.201207-036Ot  0.425
2013 Bridges JP, Ludwig MG, Mueller M, Kinzel B, Sato A, Xu Y, Whitsett JA, Ikegami M. Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. American Journal of Respiratory Cell and Molecular Biology. 49: 348-57. PMID 23590306 DOI: 10.1165/rcmb.2012-0439OC  0.424
2013 Cornett B, Snowball J, Varisco BM, Lang R, Whitsett J, Sinner D. Wntless is required for peripheral lung differentiation and pulmonary vascular development. Developmental Biology. 379: 38-52. PMID 23523683 DOI: 10.1016/J.Ydbio.2013.03.010  0.526
2013 Balli D, Ustiyan V, Zhang Y, Wang IC, Masino AJ, Ren X, Whitsett JA, Kalinichenko VV, Kalin TV. Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. The Embo Journal. 32: 231-44. PMID 23288041 DOI: 10.1038/emboj.2012.336  0.408
2013 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA. Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Developmental Biology. 375: 128-39. PMID 23266329 DOI: 10.1016/j.ydbio.2012.12.010  0.35
2013 Wan H, Liu C, Wert SE, Xu W, Liao Y, Zheng Y, Whitsett JA. CDC42 is required for structural patterning of the lung during development. Developmental Biology. 374: 46-57. PMID 23219958 DOI: 10.1016/j.ydbio.2012.11.030  0.754
2013 Ren X, Shah TA, Ustiyan V, Zhang Y, Shinn J, Chen G, Whitsett JA, Kalin TV, Kalinichenko VV. FOXM1 promotes allergen-induced goblet cell metaplasia and pulmonary inflammation. Molecular and Cellular Biology. 33: 371-86. PMID 23149934 DOI: 10.1128/MCB.00934-12  0.463
2013 Maeda Y, Whitsett J. Abstract 349: Molecular pathogenesis of mucinous adenocarcinoma of the lung. Cancer Research. 73: 349-349. DOI: 10.1158/1538-7445.Am2013-349  0.581
2013 Besnard V, Whitsett JA. Tissue Engineering for the Respiratory Epithelium. Cell-Based Therapies for Treatment of Lung Disease Principles of Tissue Engineering: Fourth Edition. 1543-1560. DOI: 10.1016/B978-0-12-398358-9.00073-2  0.379
2012 Maeda Y, Tsuchiya T, Hao H, Tompkins DH, Xu Y, Mucenski ML, Du L, Keiser AR, Fukazawa T, Naomoto Y, Nagayasu T, Whitsett JA. Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung. The Journal of Clinical Investigation. 122: 4388-400. PMID 23143308 DOI: 10.1172/JCI64048  0.773
2012 Korfhagen TR, Kitzmiller J, Chen G, Sridharan A, Haitchi HM, Hegde RS, Divanovic S, Karp CL, Whitsett JA. SAM-pointed domain ETS factor mediates epithelial cell-intrinsic innate immune signaling during airway mucous metaplasia. Proceedings of the National Academy of Sciences of the United States of America. 109: 16630-5. PMID 23012424 DOI: 10.1073/Pnas.1208092109  0.401
2012 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA. Transcriptional programs controlling perinatal lung maturation. Plos One. 7: e37046. PMID 22916088 DOI: 10.1371/journal.pone.0037046  0.445
2012 Ustiyan V, Wert SE, Ikegami M, Wang IC, Kalin TV, Whitsett JA, Kalinichenko VV. Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways. Developmental Biology. 370: 198-212. PMID 22885335 DOI: 10.1016/j.ydbio.2012.07.028  0.458
2012 Wang IC, Snyder J, Zhang Y, Lander J, Nakafuku Y, Lin J, Chen G, Kalin TV, Whitsett JA, Kalinichenko VV. Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium. Molecular and Cellular Biology. 32: 3838-50. PMID 22826436 DOI: 10.1128/MCB.00355-12  0.344
2012 Sato A, Xu Y, Whitsett JA, Ikegami M. CCAAT/enhancer binding protein-α regulates the protease/antiprotease balance required for bronchiolar epithelium regeneration. American Journal of Respiratory Cell and Molecular Biology. 47: 454-63. PMID 22652201 DOI: 10.1165/rcmb.2011-0239OC  0.456
2012 Varisco BM, Ambalavanan N, Whitsett JA, Hagood JS. Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lung. American Journal of Respiratory Cell and Molecular Biology. 46: 765-72. PMID 22268140 DOI: 10.1165/Rcmb.2011-0316Oc  0.328
2012 Plantier L, Besnard V, Xu Y, Ikegami M, Wert SE, Hunt AN, Postle AD, Whitsett JA. Activation of sterol-response element-binding proteins (SREBP) in alveolar type II cells enhances lipogenesis causing pulmonary lipotoxicity. The Journal of Biological Chemistry. 287: 10099-114. PMID 22267724 DOI: 10.1074/jbc.M111.303669  0.421
2012 Sun X, Zhang L, Xie H, Wan H, Magella B, Whitsett JA, Dey SK. Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation. Proceedings of the National Academy of Sciences of the United States of America. 109: 1145-50. PMID 22233806 DOI: 10.1073/Pnas.1118411109  0.672
2012 Ishikawa ET, Chang K, Olsson HA, Nayak RC, Ficker A, Dunn SK, Sengupta A, Whitsett J, Grimes HL, Cancelas JA. Kruppel-Like-Factor 5 (Klf-5) Controls Hematopoietic Stem Cell/Progenitor Bone Marrow Homing and Lodging Through Rab5-Mediated Expression of Active β1 Integrin Blood. 120: 113-113. DOI: 10.1182/Blood.V120.21.113.113  0.352
2012 Davies E, Chen G, Holgate S, Davies D, Whitsett J, Haitchi H. S118 IL-13 Induced Mouse Airway Inflammation Induces an Increase of Soluble ADAM33 in Bronchoalveolar Lavage Fluid, Which is Enzymatically Active and Associated with Bronchial Hyperresponsiveness Thorax. 67: A57.3-A58. DOI: 10.1136/Thoraxjnl-2012-202678.123  0.435
2011 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA. Maternal synchronization of gestational length and lung maturation. Plos One. 6: e26682. PMID 22096492 DOI: 10.1371/journal.pone.0026682  0.307
2011 Kramer EL, Hardie WD, Mushaben EM, Acciani TH, Pastura PA, Korfhagen TR, Hershey GK, Whitsett JA, Le Cras TD. Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1760-7. PMID 21903885 DOI: 10.1152/japplphysiol.00737.2011  0.326
2011 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA. Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Developmental Biology. 358: 79-90. PMID 21803035 DOI: 10.1016/j.ydbio.2011.07.020  0.3
2011 Whitsett JA, Kalinichenko VV. Integrin α6β4 defines a novel lung epithelial progenitor cell: a step forward for cell-based therapies for pulmonary disease. The Journal of Clinical Investigation. 121: 2543-5. PMID 21701072 DOI: 10.1172/JCI58704  0.414
2011 Borok Z, Whitsett JA, Bitterman PB, Thannickal VJ, Kotton DN, Reynolds SD, Krasnow MA, Bianchi DW, Morrisey EE, Hogan BL, Kurie JM, Walker DC, Radisky DC, Nishimura SL, Violette SM, et al. Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. Proceedings of the American Thoracic Society. 8: 215-22. PMID 21653526 DOI: 10.1513/pats.201012-067CB  0.378
2011 Whitsett JA, Haitchi HM, Maeda Y. Intersections between pulmonary development and disease. American Journal of Respiratory and Critical Care Medicine. 184: 401-6. PMID 21642246 DOI: 10.1164/rccm.201103-0495PP  0.387
2011 Whitsett JA, Kalinichenko VV. Notch and basal cells take center stage during airway epithelial regeneration. Cell Stem Cell. 8: 597-8. PMID 21624798 DOI: 10.1016/j.stem.2011.05.008  0.345
2011 Kenchegowda D, Swamynathan S, Gupta D, Wan H, Whitsett J, Swamynathan SK. Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells. Developmental Biology. 356: 5-18. PMID 21600198 DOI: 10.1016/J.Ydbio.2011.05.005  0.725
2011 Daikoku T, Jackson L, Besnard V, Whitsett J, Ellenson LH, Dey SK. Cell-specific conditional deletion of Pten in the uterus results in differential phenotypes. Gynecologic Oncology. 122: 424-9. PMID 21570712 DOI: 10.1016/J.Ygyno.2011.04.022  0.331
2011 Maeda Y, Chen G, Xu Y, Haitchi HM, Du L, Keiser AR, Howarth PH, Davies DE, Holgate ST, Whitsett JA. Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation. American Journal of Respiratory and Critical Care Medicine. 184: 421-9. PMID 21562130 DOI: 10.1164/rccm.201101-0106OC  0.445
2011 Plantier L, Crestani B, Wert SE, Dehoux M, Zweytick B, Guenther A, Whitsett JA. Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis. Thorax. 66: 651-7. PMID 21422041 DOI: 10.1136/thx.2010.151555  0.355
2011 Chen S, Rong M, Platteau A, Hehre D, Smith H, Ruiz P, Whitsett J, Bancalari E, Wu S. CTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L330-40. PMID 21239535 DOI: 10.1152/Ajplung.00270.2010  0.443
2011 Tompkins DH, Besnard V, Lange AW, Keiser AR, Wert SE, Bruno MD, Whitsett JA. Sox2 activates cell proliferation and differentiation in the respiratory epithelium. American Journal of Respiratory Cell and Molecular Biology. 45: 101-10. PMID 20855650 DOI: 10.1165/Rcmb.2010-0149Oc  0.79
2011 Sinner D, Cornett B, Lang R, Whitsett J. Wntless promotes pulmonary differentiation and growth Developmental Biology. 356: 164. DOI: 10.1016/J.Ydbio.2011.05.608  0.364
2010 Srikiatkhachorn A, Chintapalli J, Liu J, Jamaluddin M, Harrod KS, Whitsett JA, Enelow RI, Ramana CV. Interference with intraepithelial TNF-α signaling inhibits CD8(+) T-cell-mediated lung injury in influenza infection. Viral Immunology. 23: 639-45. PMID 21142450 DOI: 10.1089/vim.2010.0076  0.328
2010 Lin SC, Wani MA, Whitsett JA, Wells JM. Klf5 regulates lineage formation in the pre-implantation mouse embryo. Development (Cambridge, England). 137: 3953-63. PMID 20980403 DOI: 10.1242/dev.054775  0.301
2010 Wang IC, Zhang Y, Snyder J, Sutherland MJ, Burhans MS, Shannon JM, Park HJ, Whitsett JA, Kalinichenko VV. Increased expression of FoxM1 transcription factor in respiratory epithelium inhibits lung sacculation and causes Clara cell hyperplasia. Developmental Biology. 347: 301-14. PMID 20816795 DOI: 10.1016/j.ydbio.2010.08.027  0.501
2010 Hardie WD, Hagood JS, Dave V, Perl AK, Whitsett JA, Korfhagen TR, Glasser S. Signaling pathways in the epithelial origins of pulmonary fibrosis. Cell Cycle (Georgetown, Tex.). 9: 2769-76. PMID 20676040 DOI: 10.4161/cc.9.14.12268  0.341
2010 Xu Y, Zhang M, Wang Y, Kadambi P, Dave V, Lu LJ, Whitsett JA. A systems approach to mapping transcriptional networks controlling surfactant homeostasis. Bmc Genomics. 11: 451. PMID 20659319 DOI: 10.1186/1471-2164-11-451  0.393
2010 Meyer SE, Hasenstein JR, Baktula A, Velu CS, Xu Y, Wan H, Whitsett JA, Gilks CB, Grimes HL. Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival. The American Journal of Pathology. 177: 1503-13. PMID 20639455 DOI: 10.2353/Ajpath.2010.090651  0.736
2010 Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, Wills-Karp M, Whitsett JA. Foxa2 programs Th2 cell-mediated innate immunity in the developing lung. Journal of Immunology (Baltimore, Md. : 1950). 184: 6133-41. PMID 20483781 DOI: 10.4049/Jimmunol.1000223  0.76
2010 Whitsett JA. Review: The intersection of surfactant homeostasis and innate host defense of the lung: lessons from newborn infants. Innate Immunity. 16: 138-42. PMID 20351134 DOI: 10.1177/1753425910366879  0.351
2010 Galambos C, Levy H, Cannon CL, Vargas SO, Reid LM, Cleveland R, Lindeman R, deMello DE, Wert SE, Whitsett JA, Perez-Atayde AR, Kozakewich H. Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome. American Journal of Respiratory and Critical Care Medicine. 182: 549-54. PMID 20203240 DOI: 10.1164/Rccm.201002-0167Cr  0.346
2010 Besnard V, Matsuzaki Y, Clark J, Xu Y, Wert SE, Ikegami M, Stahlman MT, Weaver TE, Hunt AN, Postle AD, Whitsett JA. Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L646-59. PMID 20190032 DOI: 10.1152/ajplung.00409.2009  0.419
2010 Sato A, Whitsett JA, Scheule RK, Ikegami M. Surfactant protein-d inhibits lung inflammation caused by ventilation in premature newborn lambs. American Journal of Respiratory and Critical Care Medicine. 181: 1098-105. PMID 20133924 DOI: 10.1164/rccm.200912-1818OC  0.349
2010 Le Cras TD, Korfhagen TR, Davidson C, Schmidt S, Fenchel M, Ikegami M, Whitsett JA, Hardie WD. Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis. The American Journal of Pathology. 176: 679-86. PMID 20042669 DOI: 10.2353/Ajpath.2010.090123  0.377
2010 Whitsett JA, Wert SE, Weaver TE. Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annual Review of Medicine. 61: 105-19. PMID 19824815 DOI: 10.1146/annurev.med.60.041807.123500  0.401
2010 Noah TK, Kazanjian A, Whitsett J, Shroyer NF. SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. Experimental Cell Research. 316: 452-65. PMID 19786015 DOI: 10.1016/J.Yexcr.2009.09.020  0.465
2010 Wu S, Platteau A, Chen S, McNamara G, Whitsett J, Bancalari E. Conditional overexpression of connective tissue growth factor disrupts postnatal lung development. American Journal of Respiratory Cell and Molecular Biology. 42: 552-63. PMID 19541844 DOI: 10.1165/Rcmb.2009-0068Oc  0.487
2009 Tompkins DH, Besnard V, Lange AW, Wert SE, Keiser AR, Smith AN, Lang R, Whitsett JA. Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. Plos One. 4: e8248. PMID 20011520 DOI: 10.1371/Journal.Pone.0008248  0.791
2009 Chen G, Korfhagen TR, Xu Y, Kitzmiller J, Wert SE, Maeda Y, Gregorieff A, Clevers H, Whitsett JA. SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production. The Journal of Clinical Investigation. 119: 2914-24. PMID 19759516 DOI: 10.1172/Jci39731  0.457
2009 Wang IC, Meliton L, Ren X, Zhang Y, Balli D, Snyder J, Whitsett JA, Kalinichenko VV, Kalin TV. Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis. Plos One. 4: e6609. PMID 19672312 DOI: 10.1371/journal.pone.0006609  0.446
2009 Linnerth NM, Siwicky MD, Campbell CI, Watson KLM, Petrik JJ, Whitsett JA, Moorehead RA. Type I insulin-like growth factor receptor induces pulmonary tumorigenesis Neoplasia. 11: 672-682. PMID 19568412 DOI: 10.1593/neo.09310  0.348
2009 Lange AW, Keiser AR, Wells JM, Zorn AM, Whitsett JA. Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium. Plos One. 4: e5711. PMID 19479035 DOI: 10.1371/journal.pone.0005711  0.458
2009 Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M. C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L286-98. PMID 19465518 DOI: 10.1152/ajplung.00094.2009  0.487
2009 Korfhagen TR, Le Cras TD, Davidson CR, Schmidt SM, Ikegami M, Whitsett JA, Hardie WD. Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 41: 562-72. PMID 19244201 DOI: 10.1165/rcmb.2008-0377OC  0.345
2009 Wert SE, Whitsett JA, Nogee LM. Genetic disorders of surfactant dysfunction. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 12: 253-74. PMID 19220077 DOI: 10.2350/09-01-0586.1  0.331
2009 Kramer EL, Mushaben EM, Pastura PA, Acciani TH, Deutsch GH, Khurana Hershey GK, Korfhagen TR, Hardie WD, Whitsett JA, Le Cras TD. Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice. American Journal of Respiratory Cell and Molecular Biology. 41: 415-25. PMID 19188657 DOI: 10.1165/Rcmb.2008-0470Oc  0.375
2009 Castro M, Ramirez MI, Gern JE, Cutting G, Redding G, Hagood JS, Whitsett J, Abman S, Raj JU, Barst R, Kato GJ, Gozal D, Haddad GG, Prabhakar NR, Gauda E, et al. Strategic plan for pediatric respiratory diseases research: an NHLBI working group report. Proceedings of the American Thoracic Society. 6: 1-10. PMID 19131525 DOI: 10.1513/pats.200810-116CB  0.306
2009 Abman S, Jobe A, Chernick V, Blaisdell C, Castro M, Ramirez MI, Gern JE, Cutting G, Redding G, Hagood JS, Whitsett J, Abman S, Raj JU, Barst R, Kato GJ, et al. Strategic plan for pediatric respiratory diseases research: an NHLBI working group report. Pediatric Pulmonology. 44: 2-13. PMID 19086051 DOI: 10.1002/Ppul.20973  0.418
2009 Besnard V, Wert SE, Stahlman MT, Postle AD, Xu Y, Ikegami M, Whitsett JA. Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts. The Journal of Biological Chemistry. 284: 4018-30. PMID 19074148 DOI: 10.1074/jbc.M805388200  0.43
2008 Kalin TV, Wang IC, Meliton L, Zhang Y, Wert SE, Ren X, Snyder J, Bell SM, Graf L, Whitsett JA, Kalinichenko VV. Forkhead Box m1 transcription factor is required for perinatal lung function. Proceedings of the National Academy of Sciences of the United States of America. 105: 19330-5. PMID 19033457 DOI: 10.1073/pnas.0806748105  0.479
2008 Chaiworapongsa T, Hong JS, Hull WM, Romero R, Whitsett JA. Amniotic fluid concentration of surfactant proteins in intra-amniotic infection. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 21: 663-70. PMID 18828060 DOI: 10.1080/14767050802215664  0.311
2008 Cardoso WV, Whitsett JA. Resident cellular components of the lung: developmental aspects. Proceedings of the American Thoracic Society. 5: 767-71. PMID 18757315 DOI: 10.1513/pats.200803-026HR  0.374
2008 Franks TJ, Colby TV, Travis WD, Tuder RM, Reynolds HY, Brody AR, Cardoso WV, Crystal RG, Drake CJ, Engelhardt J, Frid M, Herzog E, Mason R, Phan SH, Randell SH, ... ... Whitsett J, et al. Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function. Proceedings of the American Thoracic Society. 5: 763-6. PMID 18757314 DOI: 10.1513/pats.200803-025HR  0.432
2008 Wan H, Luo F, Wert SE, Zhang L, Xu Y, Ikegami M, Maeda Y, Bell SM, Whitsett JA. Kruppel-like factor 5 is required for perinatal lung morphogenesis and function. Development (Cambridge, England). 135: 2563-72. PMID 18599506 DOI: 10.1242/Dev.021964  0.785
2008 Glasser SW, Senft AP, Whitsett JA, Maxfield MD, Ross GF, Richardson TR, Prows DR, Xu Y, Korfhagen TR. Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 181: 621-8. PMID 18566429  0.387
2008 Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, Yang J, DeMayo FJ, Whitsett JA, Parmacek MS, Morrisey EE. A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nature Genetics. 40: 862-70. PMID 18536717 DOI: 10.1038/Ng.157  0.414
2008 Kida H, Mucenski ML, Thitoff AR, Le Cras TD, Park KS, Ikegami M, Müller W, Whitsett JA. GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium. The American Journal of Pathology. 172: 1542-54. PMID 18467707 DOI: 10.2353/ajpath.2008.071052  0.375
2008 Hardie WD, Davidson C, Ikegami M, Leikauf GD, Le Cras TD, Prestridge A, Whitsett JA, Korfhagen TR. EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L1217-25. PMID 18424623 DOI: 10.1152/Ajplung.00020.2008  0.367
2008 Kalin TV, Meliton L, Meliton AY, Zhu X, Whitsett JA, Kalinichenko VV. Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene. American Journal of Respiratory Cell and Molecular Biology. 39: 390-9. PMID 18421012 DOI: 10.1165/rcmb.2008-0044OC  0.49
2008 Ikegami M, Falcone A, Whitsett JA. STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury Journal of Applied Physiology. 104: 1753-1760. PMID 18369093 DOI: 10.1152/japplphysiol.00875.2007  0.466
2008 Sun J, Chen H, Chen C, Whitsett JA, Mishina Y, Bringas P, Ma JC, Warburton D, Shi W. Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. The American Journal of Pathology. 172: 571-82. PMID 18258849 DOI: 10.2353/Ajpath.2008.070286  0.507
2008 Bell SM, Schreiner CM, Wert SE, Mucenski ML, Scott WJ, Whitsett JA. R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. Development (Cambridge, England). 135: 1049-58. PMID 18256198 DOI: 10.1242/dev.013359  0.372
2008 Quinton LJ, Jones MR, Robson BE, Simms BT, Whitsett JA, Mizgerd JP. Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia. American Journal of Respiratory Cell and Molecular Biology. 38: 699-706. PMID 18192501 DOI: 10.1165/Rcmb.2007-0365Oc  0.375
2008 Matsuzaki Y, Besnard V, Clark JC, Xu Y, Wert SE, Ikegami M, Whitsett JA. STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells. American Journal of Respiratory Cell and Molecular Biology. 38: 551-8. PMID 18096869 DOI: 10.1165/rcmb.2007-0311OC  0.361
2008 Davé V, Wert SE, Tanner T, Thitoff AR, Loudy DE, Whitsett JA. Conditional deletion of Pten causes bronchiolar hyperplasia. American Journal of Respiratory Cell and Molecular Biology. 38: 337-45. PMID 17921358 DOI: 10.1165/rcmb.2007-0182OC  0.422
2008 Besnard V, Whitsett JA. Tissue engineering for the Respiratory Epithelium: Is there a future for stem cell therapy in the lung? Advances in Tissue Engineering. 861-886. DOI: 10.1142/9781848161832_0039  0.381
2007 Xu Y, Ikegami M, Wang Y, Matsuzaki Y, Whitsett JA. Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells. Bmc Genomics. 8: 455. PMID 18070348 DOI: 10.1186/1471-2164-8-455  0.373
2007 Tichelaar JW, Wesselkamper SC, Chowdhury S, Yin H, Berclaz PY, Sartor MA, Leikauf GD, Whitsett JA. Duration-dependent cytoprotective versus inflammatory effects of lung epithelial fibroblast growth factor-7 expression. Experimental Lung Research. 33: 385-417. PMID 17994369 DOI: 10.1080/01902140701703226  0.747
2007 Ikegami M, Scoville EA, Grant S, Korfhagen T, Brondyk W, Scheule RK, Whitsett JA. Surfactant protein-D and surfactant inhibit endotoxin-induced pulmonary inflammation. Chest. 132: 1447-54. PMID 17925426 DOI: 10.1378/chest.07-0864  0.337
2007 Yanagi S, Kishimoto H, Kawahara K, Sasaki T, Sasaki M, Nishio M, Yajima N, Hamada K, Horie Y, Kubo H, Whitsett JA, Mak TW, Nakano T, Nakazato M, Suzuki A. Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. The Journal of Clinical Investigation. 117: 2929-40. PMID 17909629 DOI: 10.1172/JCI31854  0.42
2007 Besnard V, Xu Y, Whitsett JA. Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression American Journal of Physiology - Lung Cellular and Molecular Physiology. 293. PMID 17890326 DOI: 10.1152/ajplung.00275.2007  0.368
2007 Yamamoto H, Yun EJ, Gerber HP, Ferrara N, Whitsett JA, Vu TH. Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis. Developmental Biology. 308: 44-53. PMID 17583691 DOI: 10.1016/j.ydbio.2007.04.042  0.404
2007 Hardie WD, Korfhagen TR, Sartor MA, Prestridge A, Medvedovic M, Le Cras TD, Ikegami M, Wesselkamper SC, Davidson C, Dietsch M, Nichols W, Whitsett JA, Leikauf GD. Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 37: 309-21. PMID 17496152 DOI: 10.1165/Rcmb.2006-0455Oc  0.375
2007 Park KS, Korfhagen TR, Bruno MD, Kitzmiller JA, Wan H, Wert SE, Khurana Hershey GK, Chen G, Whitsett JA. SPDEF regulates goblet cell hyperplasia in the airway epithelium. The Journal of Clinical Investigation. 117: 978-88. PMID 17347682 DOI: 10.1172/Jci29176  0.763
2007 Maeda Y, Davé V, Whitsett JA. Transcriptional control of lung morphogenesis. Physiological Reviews. 87: 219-44. PMID 17237346 DOI: 10.1152/physrev.00028.2006  0.466
2007 Berclaz PY, Carey B, Fillipi MD, Wernke-Dollries K, Geraci N, Cush S, Richardson T, Kitzmiller J, O'connor M, Hermoyian C, Korfhagen T, Whitsett JA, Trapnell BC. GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. American Journal of Respiratory Cell and Molecular Biology. 36: 114-21. PMID 16917076 DOI: 10.1165/Rcmb.2006-0174Oc  0.725
2007 Besnard V, Whitsett JA. Progenitor cells in the respiratory system Principles of Tissue Engineering. 1113-1123. DOI: 10.1016/B978-012370615-7/50077-9  0.304
2006 Whitsett JA, Matsuzaki Y. Transcriptional Regulation of Perinatal Lung Maturation Pediatric Clinics of North America. 53: 873-887. PMID 17027615 DOI: 10.1016/j.pcl.2006.08.009  0.467
2006 Davé V, Childs T, Xu Y, Ikegami M, Besnard V, Maeda Y, Wert SE, Neilson JR, Crabtree GR, Whitsett JA. Calcineurin/Nfat signaling is required for perinatal lung maturation and function. The Journal of Clinical Investigation. 116: 2597-609. PMID 16998587 DOI: 10.1172/Jci27331  0.438
2006 Stahlman MT, Besnard V, Wert SE, Weaver TE, Dingle S, Xu Y, von Zychlin K, Olson SJ, Whitsett JA. Expression of ABCA3 in developing lung and other tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 71-83. PMID 16982851 DOI: 10.1369/jhc.6A6962.2006  0.464
2006 Whitsett JA. Disorders of lung morphogenesis Paediatric Respiratory Reviews. 7. PMID 16798581 DOI: 10.1016/j.prrv.2006.04.188  0.371
2006 Matsuzaki Y, Xu Y, Ikegami M, Besnard V, Park KS, Hull WM, Wert SE, Whitsett JA. Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 527-37. PMID 16785550 DOI: 10.4049/jimmunol.177.1.527  0.429
2006 Kingma PS, Whitsett JA. In defense of the lung: surfactant protein A and surfactant protein D Current Opinion in Pharmacology. 6: 277-283. PMID 16580255 DOI: 10.1016/j.coph.2006.02.003  0.319
2006 Park KS, Wells JM, Zorn AM, Wert SE, Whitsett JA. Sox17 influences the differentiation of respiratory epithelial cells. Developmental Biology. 294: 192-202. PMID 16574095 DOI: 10.1016/j.ydbio.2006.02.038  0.496
2006 Ikegami M, Carter K, Bishop K, Yadav A, Masterjohn E, Brondyk W, Scheule RK, Whitsett JA. Intratracheal recombinant surfactant protein d prevents endotoxin shock in the newborn preterm lamb. American Journal of Respiratory and Critical Care Medicine. 173: 1342-7. PMID 16556693 DOI: 10.1164/rccm.200509-1485OC  0.319
2006 Martis PC, Whitsett JA, Xu Y, Perl AK, Wan H, Ikegami M. C/EBPalpha is required for lung maturation at birth. Development (Cambridge, England). 133: 1155-64. PMID 16467360 DOI: 10.1242/Dev.02273  0.778
2006 Maeda Y, Hunter TC, Loudy DE, Davé V, Schreiber V, Whitsett JA. PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B. The Journal of Biological Chemistry. 281: 9600-6. PMID 16461352 DOI: 10.1074/jbc.M510435200  0.459
2006 Xu Y, Liu C, Clark JC, Whitsett JA. Functional genomic responses to cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR(delta508) in the lung. The Journal of Biological Chemistry. 281: 11279-91. PMID 16455659 DOI: 10.1074/jbc.M512072200  0.339
2006 Whitsett JA, Wert SE. Molecular Determinants of Lung Morphogenesis Kendig's Disorders of the Respiratory Tract in Children. 1-16. DOI: 10.1016/B978-0-7216-3695-5.50005-5  0.33
2006 Whitsett JA, Wert SE, Trapnell BC. Disorders of pulmonary surfactant homeostasis Principles of Molecular Medicine. 277-285. DOI: 10.1007/978-1-59259-963-9_30  0.338
2005 Lawson WE, Polosukhin VV, Stathopoulos GT, Zoia O, Han W, Lane KB, Li B, Donnelly EF, Holburn GE, Lewis KG, Collins RD, Hull WM, Glasser SW, Whitsett JA, Blackwell TS. Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. The American Journal of Pathology. 167: 1267-77. PMID 16251411 DOI: 10.1016/S0002-9440(10)61214-X  0.408
2005 Park KS, Wells JM, Zorn AM, Wert SE, Laubach VE, Fernandez LG, Whitsett JA. Transdifferentiation of ciliated cells during repair of the respiratory epithelium. American Journal of Respiratory Cell and Molecular Biology. 34: 151-7. PMID 16239640 DOI: 10.1165/rcmb.2005-0332OC  0.433
2005 Besnard V, Wert SE, Kaestner KH, Whitsett JA. Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L750-9. PMID 16214823 DOI: 10.1152/ajplung.00151.2005  0.493
2005 Whitsett JA. Surfactant proteins in innate host defense of the lung Biology of the Neonate. 88: 175-180. PMID 16210839 DOI: 10.1159/000087580  0.37
2005 Perl AK, Wert SE, Loudy DE, Shan Z, Blair PA, Whitsett JA. Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli. American Journal of Respiratory Cell and Molecular Biology. 33: 455-62. PMID 16055670 DOI: 10.1165/rcmb.2005-0180OC  0.443
2005 Floyd HS, Farnsworth CL, Kock ND, Mizesko MC, Little JL, Dance ST, Everitt J, Tichelaar J, Whitsett JA, Miller MS. Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model. Carcinogenesis. 26: 2196-206. PMID 16051643 DOI: 10.1093/carcin/bgi190  0.333
2005 Mucenski ML, Nation JM, Thitoff AR, Besnard V, Xu Y, Wert SE, Harada N, Taketo MM, Stahlman MT, Whitsett JA. Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L971-9. PMID 16040629 DOI: 10.1152/ajplung.00172.2005  0.423
2005 Ikegami M, Whitsett JA, Martis PC, Weaver TE. Reversibility of lung inflammation caused by SP-B deficiency. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L962-70. PMID 16024721 DOI: 10.1152/ajplung.00214.2005  0.382
2005 Whitsett JA, Wert SE, Xu Y. Genetic disorders of surfactant homeostasis. Biology of the Neonate. 87: 283-7. PMID 15985750 DOI: 10.1159/000084875  0.35
2005 Ikegami M, Le Cras TD, Hardie WD, Stahlman MT, Whitsett JA, Korfhagen TR. TGF-alpha perturbs surfactant homeostasis in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L34-43. PMID 15764643 DOI: 10.1152/ajplung.00407.2004  0.303
2005 Nesslein LL, Melton KR, Ikegami M, Na CL, Wert SE, Rice WR, Whitsett JA, Weaver TE. Partial SP-B deficiency perturbs lung function and causes air space abnormalities. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L1154-61. PMID 15722377 DOI: 10.1152/ajplung.00392.2004  0.313
2005 Lappalainen U, Whitsett JA, Wert SE, Tichelaar JW, Bry K. Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung. American Journal of Respiratory Cell and Molecular Biology. 32: 311-8. PMID 15668323 DOI: 10.1165/rcmb.2004-0309OC  0.324
2005 Wan H, Dingle S, Xu Y, Besnard V, Kaestner KH, Ang SL, Wert S, Stahlman MT, Whitsett JA. Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. The Journal of Biological Chemistry. 280: 13809-16. PMID 15668254 DOI: 10.1074/Jbc.M414122200  0.796
2005 Perl AK, Kist R, Shan Z, Scherer G, Whitsett JA. Normal lung development and function after Sox9 inactivation in the respiratory epithelium. Genesis (New York, N.Y. : 2000). 41: 23-32. PMID 15645446 DOI: 10.1002/gene.20093  0.438
2005 Whitsett JA, Wert SE, Trapnell BC. Genetic disorders influencing lung formation and function at birth. Human Molecular Genetics. R207-15. PMID 15358727 DOI: 10.1093/hmg/ddh252  0.403
2005 Whitsett JA. The relationship of agenesis of the lung to emphysema and cor pulmonale The Journal of Pediatrics. 146: 387. DOI: 10.1016/j.jpeds.2004.10.057  0.339
2004 Yoshida M, Whitsett JA. Interactions between pulmonary surfactant and alveolar macrophages in the pathogenesis of lung disease Cellular and Molecular Biology (Noisy-Le-Grand, France). 50. PMID 15579257  0.385
2004 Wan H, Xu Y, Ikegami M, Stahlman MT, Kaestner KH, Ang SL, Whitsett JA. Foxa2 is required for transition to air breathing at birth. Proceedings of the National Academy of Sciences of the United States of America. 101: 14449-54. PMID 15452354 DOI: 10.1073/Pnas.0404424101  0.759
2004 Miller LA, Wert SE, Clark JC, Xu Y, Perl AK, Whitsett JA. Role of Sonic hedgehog in patterning of tracheal-bronchial cartilage and the peripheral lung. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 57-71. PMID 15305287 DOI: 10.1002/dvdy.20105  0.414
2004 Reynolds PR, Mucenski ML, Le Cras TD, Nichols WC, Whitsett JA. Midkine is regulated by hypoxia and causes pulmonary vascular remodeling Journal of Biological Chemistry. 279: 37124-37132. PMID 15197188 DOI: 10.1074/Jbc.M405254200  0.33
2004 Davé V, Childs T, Whitsett JA. Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells Journal of Biological Chemistry. 279: 34578-34588. PMID 15173172 DOI: 10.1074/jbc.M404296200  0.469
2004 Khoor A, Stahlman MT, Johnson JM, Olson SJ, Whitsett JA. Forkhead box A2 transcription factor is expressed in all types of neuroendocrine lung tumors. Human Pathology. 35: 560-4. PMID 15138929 DOI: 10.1016/j.humpath.2004.01.017  0.37
2004 Le Cras TD, Hardie WD, Deutsch GH, Albertine KH, Ikegami M, Whitsett JA, Korfhagen TR. Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L718-29. PMID 15090366 DOI: 10.1152/ajplung.00084.2004  0.34
2004 Shulenin S, Nogee LM, Annilo T, Wert SE, Whitsett JA, Dean M. ABCA3 gene mutations in newborns with fatal surfactant deficiency. The New England Journal of Medicine. 350: 1296-303. PMID 15044640 DOI: 10.1056/NEJMoa032178  0.402
2004 Le Cras TD, Spitzmiller RE, Albertine KH, Greenberg JM, Whitsett JA, Akeson AL. VEGF causes pulmonary hemorrhage, hemosiderosis, and air space enlargement in neonatal mice American Journal of Physiology - Lung Cellular and Molecular Physiology. 287. PMID 15033636 DOI: 10.1152/ajplung.00050.2004  0.301
2004 Park KS, Whitsett JA, Di Palma T, Hong JH, Yaffe MB, Zannini M. TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. The Journal of Biological Chemistry. 279: 17384-90. PMID 14970209 DOI: 10.1074/Jbc.M312569200  0.476
2004 Wan H, Kaestner KH, Ang SL, Ikegami M, Finkelman FD, Stahlman MT, Fulkerson PC, Rothenberg ME, Whitsett JA. Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (Cambridge, England). 131: 953-64. PMID 14757645 DOI: 10.1242/Dev.00966  0.798
2004 Hokuto I, Ikegami M, Yoshida M, Takeda K, Akira S, Perl AK, Hull WM, Wert SE, Whitsett JA. Stat-3 is required for pulmonary homeostasis during hyperoxia. The Journal of Clinical Investigation. 113: 28-37. PMID 14702106 DOI: 10.1172/JCI19491  0.469
2004 Hokuto I, Perl AKT, Whitsett JA. FGF signaling is required for pulmonary homeostasis following hyperoxia American Journal of Physiology - Lung Cellular and Molecular Physiology. 286. PMID 14617521  0.453
2004 Whitsett JA, Wert SE, Elluru R. Trachea, Bronchi, and Lungs Handbook of Stem Cells. 1: 379-390. DOI: 10.1016/B978-012436643-5/50045-6  0.353
2003 Kalinichenko VV, Gusarova GA, Kim IM, Shin B, Yoder HM, Clark J, Sapozhnikov AM, Whitsett JA, Costa RH. Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L521-30. PMID 14607778 DOI: 10.1152/ajplung.00212.2003  0.458
2003 Liu C, Ikegami M, Stahlman MT, Dey CR, Whitsett JA. Inhibition of alveolarization and altered pulmonary mechanics in mice expressing GATA-6. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1246-54. PMID 12909592 DOI: 10.1152/ajplung.00443.2002  0.494
2003 Le Cras TD, Hardie WD, Fagan K, Whitsett JA, Korfhagen TR. Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1046-54. PMID 12896876 DOI: 10.1152/ajplung.00045.2003  0.302
2003 Mucenski ML, Wert SE, Nation JM, Loudy DE, Huelsken J, Birchmeier W, Morrisey EE, Whitsett JA. beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis. The Journal of Biological Chemistry. 278: 40231-8. PMID 12885771 DOI: 10.1074/jbc.M305892200  0.406
2003 DeFelice M, Silberschmidt D, DiLauro R, Xu Y, Wert SE, Weaver TE, Bachurski CJ, Clark JC, Whitsett JA. TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression. The Journal of Biological Chemistry. 278: 35574-83. PMID 12829717 DOI: 10.1074/jbc.M304885200  0.451
2003 Perl AK, Hokuto I, Impagnatiello MA, Christofori G, Whitsett JA. Temporal effects of Sprouty on lung morphogenesis. Developmental Biology. 258: 154-68. PMID 12781690 DOI: 10.1016/S0012-1606(03)00106-4  0.354
2003 Reynolds PR, Mucenski ML, Whitsett JA. Thyroid transcription factor (TTF) - 1 Regulates the expression of midkine (MK) during lung morphogenesis Developmental Dynamics. 227: 227-237. PMID 12761850 DOI: 10.1002/Dvdy.10304  0.507
2003 Glasser SW, Detmer EA, Ikegami M, Na CL, Stahlman MT, Whitsett JA. Pneumonitis and emphysema in sp-C gene targeted mice. The Journal of Biological Chemistry. 278: 14291-8. PMID 12519727 DOI: 10.1074/jbc.M210909200  0.389
2003 Xu Y, Clark JC, Aronow BJ, Dey CR, Liu C, Wooldridge JL, Whitsett JA. Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency. The Journal of Biological Chemistry. 278: 7674-82. PMID 12482874 DOI: 10.1074/jbc.M210277200  0.39
2003 Hokuto I, Perl AKT, Whitsett JA. Prenatal, but not postnatal, inhibition of fibroblast growth factor receptor signaling causes emphysema Journal of Biological Chemistry. 278: 415-421. PMID 12399466 DOI: 10.1074/jbc.M208328200  0.417
2002 Whitsett JA, Weaver TE. Hydrophobic surfactant proteins in lung function and disease New England Journal of Medicine. 347: 2141-2148. PMID 12501227 DOI: 10.1056/NEJMra022387  0.318
2002 Berclaz PY, Zsengellér Z, Shibata Y, Otake K, Strasbaugh S, Whitsett JA, Trapnell BC. Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU.1. Journal of Immunology (Baltimore, Md. : 1950). 169: 6332-42. PMID 12444140 DOI: 10.4049/Jimmunol.169.11.6332  0.729
2002 Berclaz PY, Shibata Y, Whitsett JA, Trapnell BC. GM-CSF, via PU.1, regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma -mediated molecular connection between innate and adaptive immunity in the lung. Blood. 100: 4193-200. PMID 12393686 DOI: 10.1182/Blood-2002-04-1102  0.729
2002 Perl AK, Wert SE, Nagy A, Lobe CG, Whitsett JA. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proceedings of the National Academy of Sciences of the United States of America. 99: 10482-7. PMID 12145322 DOI: 10.1073/Pnas.152238499  0.474
2002 Liu C, Morrisey EE, Whitsett JA. GATA-6 is required for maturation of the lung in late gestation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L468-75. PMID 12114210 DOI: 10.1152/Ajplung.00044.2002  0.471
2002 Kalinichenko VV, Zhou Y, Shin B, Stolz DB, Watkins SC, Whitsett JA, Costa RH. Wild-type levels of the mouse Forkhead Box f1 gene are essential for lung repair. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1253-65. PMID 12003781 DOI: 10.1152/Ajplung.00463.2001  0.474
2002 Stahlman MT, Gray ME, Hull WM, Whitsett JA. Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 50: 651-60. PMID 11967276 DOI: 10.1177/002215540205000506  0.324
2002 Yang H, Lu MM, Zhang L, Whitsett JA, Morrisey EE. GATA6 regulates differentiation of distal lung epithelium. Development (Cambridge, England). 129: 2233-46. PMID 11959831  0.517
2002 Lim L, Kalinichenko VV, Whitsett JA, Costa RH. Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1012-22. PMID 11943666 DOI: 10.1152/ajplung.00371.2001  0.421
2002 Whitsett JA, Clark JC, Picard L, Tichelaar JW, Wert SE, Itoh N, Perl AK, Stahlman MT. Fibroblast growth factor 18 influences proximal programming during lung morphogenesis. The Journal of Biological Chemistry. 277: 22743-9. PMID 11927601 DOI: 10.1074/jbc.M202253200  0.465
2002 McCormack FX, Whitsett JA. The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung Journal of Clinical Investigation. 109: 707-712. PMID 11901176 DOI: 10.1172/JCI200215293  0.345
2002 Whitsett JA. Intrinsic and innate defenses in the lung: Intersection of pathways regulating lung morphogenesis, host defense, and repair Journal of Clinical Investigation. 109: 565-569. PMID 11877462 DOI: 10.1172/JCI200215209  0.357
2002 Perl AKT, Tichelaar JW, Whitsett JA. Conditional gene expression in the respiratory epithelium of the mouse Transgenic Research. 11: 21-29. PMID 11874100 DOI: 10.1023/A:1013986627504  0.355
2002 Johnston SD, Daniels CB, Cenzato D, Whitsett JA, Orgeig S. The pulmonary surfactant system matures upon pipping in the freshwater turtle Chelydra serpentina Journal of Experimental Biology. 205: 415-425. PMID 11854378  0.45
2002 Baughman RP, Henderson RF, Whitsett J, Gunther KL, Keeton DA, Waide JJ, Zaccardelli DS, Pattishall EN, Rashkin MC. Surfactant replacement for ventilator-associated pneumonia: a preliminary report. Respiration; International Review of Thoracic Diseases. 69: 57-62. PMID 11844964 DOI: 10.1159/000049371  0.331
2002 LeVine AM, Hartshorn K, Elliott J, Whitsett J, Korfhagen T. Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection American Journal of Physiology - Lung Cellular and Molecular Physiology. 282. PMID 11839553 DOI: 10.1152/Ajplung.00280.2001  0.441
2002 Trapnell BC, Whitsett JA. GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense Annual Review of Physiology. 64: 775-802. PMID 11826288 DOI: 10.1146/annurev.physiol.64.090601.113847  0.396
2002 Wert SE, Dey CR, Blair PA, Kimura S, Whitsett JA. Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation. Developmental Biology. 242: 75-87. PMID 11820807 DOI: 10.1006/dbio.2001.0540  0.515
2002 Liu C, Glasser SW, Wan H, Whitsett JA. GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. The Journal of Biological Chemistry. 277: 4519-25. PMID 11733512 DOI: 10.1074/Jbc.M107585200  0.697
2001 Miller LAD, Wert SE, Whitsett JA. Immunolocalization of sonic hedgehog (Shh) in developing mouse lung Journal of Histochemistry and Cytochemistry. 49: 1593-1603. PMID 11724907 DOI: 10.1177/002215540104901213  0.414
2001 Krane CM, Fortner CN, Hand AR, McGraw DW, Lorenz JN, Wert SE, Towne JE, Paul RJ, Whitsett JA, Menon AG. Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation. Proceedings of the National Academy of Sciences of the United States of America. 98: 14114-9. PMID 11707570 DOI: 10.1073/Pnas.231273398  0.435
2001 Shibata Y, Berclaz PY, Chroneos ZC, Yoshida M, Whitsett JA, Trapnell BC. GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity. 15: 557-67. PMID 11672538 DOI: 10.1016/S1074-7613(01)00218-7  0.748
2001 Ikegami M, Hull WM, Yoshida M, Wert SE, Whitsett JA. SP-D and GM-CSF regulate surfactant homeostasis via distinct mechanisms. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L697-703. PMID 11504698 DOI: 10.1152/ajplung.2001.281.3.L697  0.349
2001 Amin RS, Wert SE, Baughman RP, Tomashefski JF, Nogee LM, Brody AS, Hull WM, Whitsett JA. Surfactant protein deficiency in familial interstitial lung disease. The Journal of Pediatrics. 139: 85-92. PMID 11445799 DOI: 10.1067/Mpd.2001.114545  0.335
2001 Zhou H, Morotti RA, Profitt SA, Langston C, Wert SE, Whitsett JA, Greco MA. Expression of thyroid transcription factor-1, surfactant proteins, type I cell-associated antigen, and Clara cell secretory protein in pulmonary hypoplasia. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 4: 364-71. PMID 11441338 DOI: 10.1007/s10024001-0002-9  0.41
2001 Kalinichenko VV, Lim L, Stolz DB, Shin B, Rausa FM, Clark J, Whitsett JA, Watkins SC, Costa RH. Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor. Developmental Biology. 235: 489-506. PMID 11437453 DOI: 10.1006/Dbio.2001.0322  0.46
2001 Miller LD, Wert SE, Whitsett JA. Surfactant proteins and cell markers in the respiratory epithelium of the amphibian, Ambystoma mexicanum. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 129: 141-9. PMID 11369539 DOI: 10.1016/S1095-6433(01)00311-7  0.776
2001 Glasser SW, Burhans MS, Korfhagen TR, Na CL, Sly PD, Ross GF, Ikegami M, Whitsett JA. Altered stability of pulmonary surfactant in SP-C-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 6366-71. PMID 11344267 DOI: 10.1073/pnas.101500298  0.355
2001 LeVine AM, Whitsett JA. Pulmonary collectins and innate host defense of the lung Microbes and Infection. 3: 161-166. PMID 11251302 DOI: 10.1016/S1286-4579(00)01363-0  0.327
2001 Epperly MW, Travis EL, Whitsett JA, Raineri I, Epstein CJ, Greenberger JS. Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection. International Journal of Cancer. Journal International Du Cancer. 96: 11-21. PMID 11241326 DOI: 10.1002/1097-0215(20010220)96:1<11::Aid-Ijc2>3.0.Co;2-R  0.365
2001 Clark JC, Tichelaar JW, Wert SE, Itoh N, Perl AK, Stahlman MT, Whitsett JA. FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L705-15. PMID 11238011 DOI: 10.1152/ajplung.2001.280.4.L705  0.471
2001 Zsengellér ZK, Ross GF, Trapnell BC, Szabó C, Whitsett JA. Adenovirus infection increases iNOS and peroxynitrite production in the lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L503-11. PMID 11159034 DOI: 10.1152/Ajplung.2001.280.3.L503  0.395
2000 Naltner A, Wert S, Whitsett JA, Yan C. Temporal/spatial expression of nuclear receptor coactivators in the mouse lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L1066-74. PMID 11076796 DOI: 10.1152/ajplung.2000.279.6.L1066  0.389
2000 Chroneos ZC, Wert SE, Livingston JL, Hassett DJ, Whitsett JA. Role of cystic fibrosis transmembrane conductance regulator in pulmonary clearance of Pseudomonas aeruginosa in vivo. Journal of Immunology (Baltimore, Md. : 1950). 165: 3941-50. PMID 11034402 DOI: 10.4049/Jimmunol.165.7.3941  0.418
2000 LeVine AM, Whitsett JA, Gwozdz JA, Richardson TR, Fisher JH, Burhans MS, Korfhagen TR. Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung. Journal of Immunology (Baltimore, Md. : 1950). 165: 3934-40. PMID 11034401 DOI: 10.4049/jimmunol.165.7.3934  0.31
2000 Hayashida S, Harrod KS, Whitsett JA. Regulation and function of CCSP during pulmonary Pseudomonas aeruginosa infection in vivo American Journal of Physiology - Lung Cellular and Molecular Physiology. 279. PMID 10956619  0.406
2000 Ikegami M, Jobe AH, Whitsett J, Korfhagen T. Tolerance of SP-A-deficient mice to hyperoxia or exercise Journal of Applied Physiology. 89: 644-648. PMID 10926649 DOI: 10.1152/Jappl.2000.89.2.644  0.373
2000 Reed JA, Ikegami M, Robb L, Begley CG, Ross G, Whitsett JA. Distinct changes in pulmonary surfactant homeostasis in common beta-chain- and GM-CSF-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L1164-71. PMID 10835321 DOI: 10.1152/Ajplung.2000.278.6.L1164  0.376
2000 Tichelaar JW, Lu W, Whitsett JA. Conditional expression of fibroblast growth factor-7 in the developing and mature lung Journal of Biological Chemistry. 275: 11858-11864. PMID 10766812 DOI: 10.1074/jbc.275.16.11858  0.518
2000 Harrod KS, Mounday AD, Whitsett JA. Adenoviral E3-14.7K protein in LPS-induced lung inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L631-9. PMID 10749739 DOI: 10.1152/ajplung.2000.278.4.L631  0.308
2000 Paine R, Preston AM, Wilcoxen S, Jin H, Siu BB, Morris SB, Reed JA, Ross G, Whitsett JA, Beck JM. Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 2602-9. PMID 10679099 DOI: 10.4049/jimmunol.164.5.2602  0.309
2000 Byrd-Gloster AL, Khoor A, Glass LF, Messina JL, Whitsett JA, Livingston SK, Cagle PT. Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor. Human Pathology. 31: 58-62. PMID 10665914 DOI: 10.1016/S0046-8177(00)80199-9  0.345
2000 Bruno MD, Korfhagen TR, Liu C, Morrisey EE, Whitsett JA. GATA-6 activates transcription of surfactant protein A Journal of Biological Chemistry. 275: 1043-1049. PMID 10625644 DOI: 10.1074/Jbc.275.2.1043  0.378
2000 Whitsett JA. Conservation of pathways mediating lung morphogenesis and surfactant protein gene expression Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 126: S105. DOI: 10.1016/S0305-0491(00)80207-2  0.384
1999 Ikegami M, Harrod KS, Whitsett JA, Jobe AH. CCSP deficiency does not alter surfactant homeostasis during adenoviral infection. The American Journal of Physiology. 277: L983-7. PMID 10564184 DOI: 10.1152/ajplung.1999.277.5.L983  0.358
1999 Tokieda K, Iwamoto HS, Bachurski C, Wert SE, Hull WM, Ikeda K, Whitsett JA. Surfactant protein-B-deficient mice are susceptible to hyperoxic lung injury. American Journal of Respiratory Cell and Molecular Biology. 21: 463-72. PMID 10502556 DOI: 10.1165/ajrcmb.21.4.3436  0.3
1999 Harrod KS, Trapnell BC, Otake K, Korfhagen TR, Whitsett JA. SP-A enhances viral clearance and inhibits inflammation after pulmonary adenoviral infection. The American Journal of Physiology. 277: L580-8. PMID 10484466 DOI: 10.1152/ajplung.1999.277.3.L580  0.386
1999 Tichelaar JW, Lim L, Costa RH, Whitsett JA. HNF-3/Forkhead homologue-4 influences lung morphogenesis and respiratory epithelial cell differentiation in vivo Developmental Biology. 213: 405-417. PMID 10479457 DOI: 10.1006/dbio.1999.9380  0.5
1999 Perl AKT, Whitsett JA. Molecular mechanisms controlling lung morphogenesis Clinical Genetics. 56: 14-27. PMID 10466413 DOI: 10.1034/j.1399-0004.1999.560103.x  0.395
1999 Hardie WD, Bejarano PA, Miller MA, Yankaskas JR, Ritter JH, Whitsett JA, Korfhagen TR. Immunolocalization of transforming growth factor alpha and epidermal growth factor receptor in lungs of patients with cystic fibrosis. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 2: 415-23. PMID 10441618 DOI: 10.1007/S100249900144  0.39
1999 Whitsett JA, Tichelaar JW. Forkhead transcription factor HFH-4 and respiratory epithelial cell differentiation American Journal of Respiratory Cell and Molecular Biology. 21: 153-154. PMID 10423395  0.326
1999 Khoor A, Whitsett JA, Stahlman MT, Olson SJ, Cagle PT. Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma. Human Pathology. 30: 695-700. PMID 10374779 DOI: 10.1016/S0046-8177(99)90096-5  0.337
1999 Morotti RA, Cangiarella J, Gutierrez MC, Jagirdar J, Askin F, Singh G, Profitt SA, Wert SE, Whitsett JA, Greco MA. Congenital cystic adenomatoid malformation of the lung (CCAM): evaluation of the cellular components. Human Pathology. 30: 618-25. PMID 10374767 DOI: 10.1016/S0046-8177(99)90084-9  0.365
1999 Tichelaar JW, Wert SE, Costa RH, Kimura S, Whitsett JA. HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 47: 823-32. PMID 10330459 DOI: 10.1177/002215549904700612  0.445
1999 Liu AN, Mohammed AZ, Rice WR, Fiedeldey DT, Liebermann JS, Whitsett JA, Braciale TJ, Enelow RI. Perforin-independent CD8+ T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-α: Relative insensitivity to Fas ligand American Journal of Respiratory Cell and Molecular Biology. 20: 849-858. PMID 10226053 DOI: 10.1165/Ajrcmb.20.5.3585  0.31
1999 Reed JA, Ikegami M, Cianciolo ER, Lu W, Cho PS, Hull W, Jobe AH, Whitsett JA. Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM- CSF-deficient mice American Journal of Physiology - Lung Cellular and Molecular Physiology. 276. PMID 10198353 DOI: 10.1152/ajplung.1999.276.4.l556  0.338
1999 LeVine AM, Gwozdz J, Stark J, Bruno M, Whitsett J, Korfhagen T. Surfactant protein-A enhances respiratory syncytial virus clearance in vivo. The Journal of Clinical Investigation. 103: 1015-21. PMID 10194474 DOI: 10.1172/Jci5849  0.437
1999 Sekhon HS, Jia Y, Raab R, Kuryatov A, Pankow JF, Whitsett JA, Lindstrom J, Spindel ER. Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys. The Journal of Clinical Investigation. 103: 637-47. PMID 10074480 DOI: 10.1172/Jci5232  0.311
1999 Ghaffari M, Whitsett JA, Yan C. Inhibition of hSP-B promoter in respiratory epithelial cells by a dominant negative retinoic acid receptor American Journal of Physiology - Lung Cellular and Molecular Physiology. 276. PMID 10070102  0.358
1999 Zsengellér ZK, Halbert C, Miller AD, Wert SE, Whitsett JA, Bachurski CJ. Keratinocyte growth factor stimulates transduction of the respiratory epithelium by retroviral vectors. Human Gene Therapy. 10: 341-53. PMID 10048387 DOI: 10.1089/10430349950018797  0.436
1999 Burke LM, Rush WI, Khoor A, Mackay B, Oliveira P, Whitsett JA, Singh G, Turnicky R, Fleming MV, Koss MN, Travis WD. Alveolar adenoma: a histochemical, immunohistochemical, and ultrastructural analysis of 17 cases. Human Pathology. 30: 158-67. PMID 10029443 DOI: 10.1016/S0046-8177(99)90270-8  0.332
1999 LeVine AM, Reed JA, Kurak KE, Cianciolo E, Whitsett JA. GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection. The Journal of Clinical Investigation. 103: 563-9. PMID 10021465 DOI: 10.1172/JCI5212  0.315
1999 LeVine AM, Kurak KE, Wright JR, Watford WT, Bruno MD, Ross GF, Whitsett JA, Korfhagen TR. Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice. American Journal of Respiratory Cell and Molecular Biology. 20: 279-86. PMID 9922219 DOI: 10.1165/Ajrcmb.20.2.3303  0.304
1999 Shaw-White JR, Bruno MD, Whitsett JA. GATA-6 activates transcription of thyroid transcription factor-1 Journal of Biological Chemistry. 274: 2658-2664. PMID 9915795 DOI: 10.1074/jbc.274.5.2658  0.45
1999 Vanderzwan J, McCaig L, Mehta S, Joseph M, Whitsett J, McCormack DG, Lewis JF. Characterizing alterations in the pulmonary surfactant system in a rat model of Pseudomonas aeruginosa pneumonia. The European Respiratory Journal. 12: 1388-96. PMID 9877497 DOI: 10.1183/09031936.98.12061388  0.467
1999 Levine AM, Gwozdz J, Fisher J, Whitsett J, Korfhagen T. Surfactant protein-a but not SP-D deficient mice are susceptible to bacterial infection in the lung Critical Care Medicine. 27. DOI: 10.1097/00003246-199912001-00317  0.382
1998 Harrod KS, Mounday AD, Stripp BR, Whitsett JA. Clara cell secretory protein decreases lung inflammation after acute virus infection. American Journal of Physiology. Lung Cellular and Molecular Physiology. 275: L924-L930. PMID 29586202 DOI: 10.1152/Ajplung.1998.275.5.L924  0.452
1998 Ross G, Bruno, Uyeda M, Suzuki K, Nagao K, Whitsett J, Korfhagen T. Enhanced reporter gene expression in cells transfected in the presence of DMI-2, an acid nuclease inhibitor Gene Therapy. 5: 1244-1250. PMID 9930326 DOI: 10.1038/Sj.Gt.3300721  0.428
1998 Zeng X, Yutzey KE, Whitsett JA. Thyroid transcription factor-1, hepatocyte nuclear factor-3β and surfactant protein A and B in the developing chick lung Journal of Anatomy. 193: 399-408. PMID 9877295 DOI: 10.1046/J.1469-7580.1998.19330399.X  0.457
1998 Harlamert HA, Mira J, Bejarano PA, Baughman RP, Miller MA, Whitsett JA, Yassin R. Thyroid transcription factor-1 and cytokeratins 7 and 20 in pulmonary and breast carcinoma. Acta Cytologica. 42: 1382-8. PMID 9850647 DOI: 10.1159/000332172  0.34
1998 Whitsett JA, Glasser SW. Regulation of surfactant protein gene transcription Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1408: 303-311. PMID 9813380 DOI: 10.1016/S0925-4439(98)00076-3  0.341
1998 LeVine AM, Kurak KE, Bruno MD, Stark JM, Whitsett JA, Korfhagen TR. Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection. American Journal of Respiratory Cell and Molecular Biology. 19: 700-8. PMID 9761768 DOI: 10.1165/ajrcmb.19.4.3254  0.313
1998 Zsengellér ZK, Reed JA, Bachurski CJ, LeVine AM, Forry-Schaudies S, Hirsch R, Whitsett JA. Adenovirus-mediated granulocyte-macrophage colony-stimulating factor improves lung pathology of pulmonary alveolar proteinosis in granulocyte-macrophage colony-stimulating factor-deficient mice. Human Gene Therapy. 9: 2101-9. PMID 9759936 DOI: 10.1089/Hum.1998.9.14-2101  0.357
1998 Harrod KS, Hermiston TW, Trapnell BC, Wold WSM, Whitsett JA. Lung-specific expression of adenovirus E3-14.7K in transgenic mice attenuates adenoviral vector-mediated lung inflammation and enhances transgene expression Human Gene Therapy. 9: 1885-1898. PMID 9741427 DOI: 10.1089/hum.1998.9.13-1885  0.364
1998 Whitsett J. A lungful of transcription factors Nature Genetics. 20: 7-8. PMID 9731520 DOI: 10.1038/1654  0.361
1998 Reed JA, Whitsett JA. Granulocyte-macrophage colony-stimulating factor and pulmonary surfactant homeostasis Proceedings of the Association of American Physicians. 110: 321-332. PMID 9686680  0.351
1998 Stahlman MT, Gray ME, Whitsett JA. Temporal-spatial distribution of hepatocyte nuclear factor-3beta in developing human lung and other foregut derivatives. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 955-62. PMID 9671445 DOI: 10.1177/002215549804600809  0.333
1998 Zeng X, Wert SE, Federici R, Peters KG, Whitsett JA. VEGF enhances pulmonary vasculogenesis and disrupts lung morphogenesis in vivo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 211: 215-27. PMID 9520109 DOI: 10.1002/(SICI)1097-0177(199803)211:3<215::AID-AJA3>3.0.CO;2-K  0.43
1998 Sullivan LC, Daniels CB, Phillips ID, Orgeig S, Whitsett JA. Conservation of surfactant protein A: Evidence for a single origin for vertebrate pulmonary surfactant Journal of Molecular Evolution. 46: 131-138. PMID 9452514 DOI: 10.1007/PL00006287  0.33
1998 Zhou L, Dey CR, Wert SE, Yan C, Costa RH, Whitsett JA. Hepatocyte nuclear factor-3beta limits cellular diversity in the developing respiratory epithelium and alters lung morphogenesis in vivo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 210: 305-14. PMID 9389455 DOI: 10.1002/(SICI)1097-0177(199711)210:3<305::AID-AJA10>3.0.CO;2-9  0.399
1998 Lcvine AM, Reed J, Kurak K, Korfhageo T, Whitsett J. Group B streptococcal infection in GM-CSF deficient mice Critical Care Medicine. 26. DOI: 10.1097/00003246-199801001-00328  0.471
1997 Ikegami M, Jobe AH, Reed JAH, Whitsett JA. Surfactant metabolic consequences of overexpression of GM-CSF in the epithelium of GM-CSF-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 273: L709-L714. PMID 29585853 DOI: 10.1152/ajplung.1997.273.4.L709  0.339
1997 Reed JAH, Rice WR, Zsengellér ZK, Wert SE, Dranoff G, Whitsett JA. GM-CSF enhances lung growth and causes alveolar type II epithelial cell hyperplasia in transgenic mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 273: L715-L725. PMID 29585841 DOI: 10.1152/ajplung.1997.273.4.L715  0.392
1997 Tokieda K, Whitsett JA, Clark JC, Weaver TE, Ikeda K, McConnell KB, Jobe AH, Ikegami M, Iwamoto HS. Pulmonary dysfunction in neonatal SP-B-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 273: L875-L882. PMID 29585840 DOI: 10.1152/ajplung.1997.273.4.L875  0.301
1997 Ghaffari M, Zeng X, Whitsett JA, Yan C. Nuclear localization domain of thyroid transcription factor-1 in respiratory epithelial cells Biochemical Journal. 328: 757-761. PMID 9396717  0.376
1997 Jain-Vora S, Wert SE, Temann UA, Rankin JA, Whitsett JA. Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung. American Journal of Respiratory Cell and Molecular Biology. 17: 541-51. PMID 9374105 DOI: 10.1165/ajrcmb.17.5.2883  0.431
1997 Zsengellér ZK, Wert SE, Bachurski CJ, Kirwin KL, Trapnell BC, Whitsett JA. Recombinant adenoviral vector disrupts surfactant homeostasis in mouse lung. Human Gene Therapy. 8: 1331-44. PMID 9295128 DOI: 10.1089/hum.1997.8.11-1331  0.402
1997 Horowitz AD, Kurak K, Moussavian B, Whitsett JA, Wert SE, Hull WM, McNanie J, Ikegami M. Preferential uptake of small-aggregate fraction of pulmonary surfactant in vitro. The American Journal of Physiology. 273: L468-77. PMID 9277461 DOI: 10.1152/ajplung.1997.273.2.L468  0.308
1997 Wikenheiser KA, Whitsett JA. Tumor Progression and Cellular Differentiation of Pulmonary Adenocarcinomas in SV40 Large T Antigen Transgenic Mice American Journal of Respiratory Cell and Molecular Biology. 16: 713-723. PMID 9191473  0.376
1997 Ikegami M, Korfhagen TR, Bruno MD, Whitsett JA, Jobe AH. Surfactant metabolism in surfactant protein A-deficient mice. The American Journal of Physiology. 272: L479-85. PMID 9124605 DOI: 10.1152/ajplung.1997.272.3.L479  0.305
1997 Zhang L, Wikenheiser KA, Whitsett JA. Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo Human Gene Therapy. 8: 563-574. PMID 9095408  0.315
1997 Holzinger A, Dingle S, Bejarano PA, Miller MA, Weaver TE, DiLauro R, Whitsett JA. Monoclonal antibody to thyroid transcription factor-1: production, characterization, and usefulness in tumor diagnosis. Hybridoma. 15: 49-53. PMID 9064286 DOI: 10.1089/hyb.1996.15.49  0.321
1997 Jobe AH, Ikegami M, Yei S, Whitsett JA, Trapnell B. Surfactant effects on aerosolized and instilled adenoviral-mediated gene transfer. Human Gene Therapy. 7: 697-704. PMID 8919591 DOI: 10.1089/hum.1996.7.6-697  0.326
1996 Zhou L, Graeff RW, McCray PB, Simonet WS, Whitsett JA. Keratinocyte growth factor stimulates CFTR-independent fluid secretion in the fetal lung in vitro. The American Journal of Physiology. 271: L987-94. PMID 8997270 DOI: 10.1152/ajplung.1996.271.6.L987  0.305
1996 Whitsett JA, Zhou L. Use of transgenic mice to study autocrine-paracrine signaling in lung morphogenesis and differentiation Clinics in Perinatology. 23: 753-769. PMID 8982569  0.417
1996 Stripp BR, Lund J, Mango GW, Doyen KC, Johnston C, Hultenby K, Nord M, Whitsett JA. Clara cell secretory protein: a determinant of PCB bioaccumulation in mammals. The American Journal of Physiology. 271: L656-64. PMID 8897914 DOI: 10.1152/Ajplung.1996.271.4.L656  0.391
1996 Wilmott RW, Amin RS, Perez CR, Wert SE, Keller G, Boivin GP, Hirsch R, De Inocencio J, Lu P, Reising SF, Yei S, Whitsett JA, Trapnell BC. Safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lungs of nonhuman primates. Human Gene Therapy. 7: 301-18. PMID 8835218 DOI: 10.1089/Hum.1996.7.3-301  0.319
1996 Zhou L, Lim L, Costa RH, Whitsett JA. Thyroid transcription factor-1, hepatocyte nuclear factor-3β, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung Journal of Histochemistry and Cytochemistry. 44: 1183-1193. PMID 8813084  0.377
1996 Korfhagen TR, Bruno MD, Ross GF, Huelsman KM, Ikegami M, Jobe AH, Wert SE, Stripp BR, Morris RE, Glasser SW, Bachurski CJ, Iwamoto HS, Whitsett JA. Altered surfactant function and structure in SP-A gene targeted mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 9594-9. PMID 8790375 DOI: 10.1073/Pnas.93.18.9594  0.353
1996 Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, Flavell RA. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proceedings of the National Academy of Sciences of the United States of America. 93: 7821-5. PMID 8755560 DOI: 10.1073/Pnas.93.15.7821  0.418
1996 LeVine AM, Lotze A, Stanley S, Stroud C, O'Donnell R, Whitsett J, Pollack MM. Surfactant content in children with inflammatory lung disease. Critical Care Medicine. 24: 1062-7. PMID 8681574 DOI: 10.1097/00003246-199606000-00029  0.362
1996 Stahlman MT, Gray ME, Whitsett JA. Expression of thyroid transcription factor-1(TTF-1) in fetal and neonatal human lung. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 44: 673-8. PMID 8675988 DOI: 10.1177/44.7.8675988  0.465
1996 Ikeda K, Shaw-White JR, Wert SE, Whitsett JA. Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells. Molecular and Cellular Biology. 16: 3626-36. PMID 8668179 DOI: 10.1128/MCB.16.7.3626  0.346
1996 Chroneos ZC, Abdolrasulnia R, Whitsett JA, Rice WR, Shepherd VL. Purification of a cell-surface receptor for surfactant protein A Journal of Biological Chemistry. 271: 16375-16383. PMID 8663107 DOI: 10.1074/Jbc.271.27.16375  0.311
1996 Whitsett JA, Korfhagen TR. Regulation of Gene Transcription in Respiratory Epithelial Cells American Journal of Respiratory Cell and Molecular Biology. 14: 118-120. PMID 8630260  0.333
1996 Zhou L, Dey CR, Wert SE, Whitsett JA. Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-beta 1 chimeric gene. Developmental Biology. 175: 227-38. PMID 8626028 DOI: 10.1006/dbio.1996.0110  0.362
1996 Simonet WS, DeRose ML, Bucay N, Nguyen HQ, Wert SE, Zhou L, Ulich TR, Thomason A, Danilenko DM, Whitsett JA. Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung. Proceedings of the National Academy of Sciences of the United States of America. 92: 12461-5. PMID 8618921 DOI: 10.1073/pnas.92.26.12461  0.488
1996 Huffman JA, Hull WM, Dranoff G, Mulligan RC, Whitsett JA. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. The Journal of Clinical Investigation. 97: 649-55. PMID 8609219 DOI: 10.1172/Jci118461  0.338
1996 Wert SE, Profitt SA, Kirwin KL, Langston C, Whitsett JA. ACINAR DYSPLASIA IS ASSOCIATED WITH THE ABSENCE OF TTF-1 AND HNF-3β EXPRESSION DURING HUMAN LUNG DEVELOPMENT. † 2117 Pediatric Research. 39: 355-355. DOI: 10.1203/00006450-199604001-02141  0.308
1995 Bruno MD, Bohinski RJ, Huelsman KM, Whitsett JA, Korfhagen TR. Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1. The Journal of Biological Chemistry. 270: 6531-6. PMID 7896788 DOI: 10.1074/jbc.270.12.6531  0.379
1995 DiCosmo B, Geba G, Picarella D, Elias JA, Rankin JA, Stripp B, Whitsett JA, Flavell RA. Expression of interleukin-6 by airway epithelial cells. Effects on airway inflammation and hyperreactivity in transgenic mice. Chest. 107: 131S. PMID 7874993 DOI: 10.1378/Chest.107.3_Supplement.131S  0.354
1995 Ikeda K, Clark JC, Shaw-White JR, Stahlman MT, Boutell CJ, Whitsett JA. Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells. The Journal of Biological Chemistry. 270: 8108-14. PMID 7713914 DOI: 10.1074/jbc.270.14.8108  0.432
1995 Zsengeller ZK, Wert SE, Hull WM, Hu X, Yei S, Trapnell BC, Whitsett JA. Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice. Human Gene Therapy. 6: 457-67. PMID 7612702 DOI: 10.1089/hum.1995.6.4-457  0.41
1995 Vincent MC, Trapnell BC, Baughman RP, Wert SE, Whitsett JA, Iwamoto HS. Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero. Human Gene Therapy. 6: 1019-28. PMID 7578414 DOI: 10.1089/hum.1995.6.8-1019  0.348
1995 Yan C, Sever Z, Whitsett JA. Upstream enhancer activity in the human surfactant protein B gene is mediated by thyroid transcription factor 1 Journal of Biological Chemistry. 270: 24852-24857. PMID 7559607 DOI: 10.1074/jbc.270.42.24852  0.316
1995 Miyazaki Y, Araki K, Vesin C, Garcia I, Kapanci Y, Whitsett JA, Piguet PF, Vassalli P. Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis. The Journal of Clinical Investigation. 96: 250-9. PMID 7542280 DOI: 10.1172/JCI118029  0.383
1995 Whitsett JA, Nogee LM, Weaver TE, Horowitz AD. Human surfactant protein B: structure, function, regulation, and genetic disease. Physiological Reviews. 75: 749-57. PMID 7480161 DOI: 10.1152/physrev.1995.75.4.749  0.311
1994 Wikenheiser KA, Vorbroker DK, Rice WR, Clark JC, Bachurski CJ, Oie HK, Whitsett JA. Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 11029-33. PMID 8248207 DOI: 10.1073/pnas.90.23.11029  0.424
1994 Dranoff G, Crawford AD, Sadelain M, Ream B, Rashid A, Bronson RT, Dickersin GR, Bachurski CJ, Mark EL, Whitsett JA. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science (New York, N.Y.). 264: 713-6. PMID 8171324 DOI: 10.1126/Science.8171324  0.381
1994 Korfhagen TR, Swantz RJ, Wert SE, McCarty JM, Kerlakian CB, Glasser SW, Whitsett JA. Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice. The Journal of Clinical Investigation. 93: 1691-9. PMID 8163670 DOI: 10.1172/JCI117152  0.461
1994 Bohinski RJ, Di Lauro R, Whitsett JA. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis Molecular and Cellular Biology. 14: 5671-5681. PMID 8065304  0.386
1994 Khoor A, Stahlman MT, Gray ME, Whitsett JA. Temporal-spatial distribution of SP-B and SP-C proteins and mRNAs in developing respiratory epithelium of human lung. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 42: 1187-99. PMID 8064126 DOI: 10.1177/42.9.8064126  0.312
1994 Lewis JF, Veldhuizen R, Possmayer F, Sibbald W, Whitsett J, Qanbar R, Mccaig L. Altered alveolar surfactant is an early marker of acute lung injury in septic adult sheep American Journal of Respiratory and Critical Care Medicine. 150: 123-130. PMID 8025737 DOI: 10.1164/Ajrccm.150.1.8025737  0.397
1994 Glasser SW, Korfhagen TR, Wert SE, Whitsett JA. Transgenic models for study of pulmonary development and disease. The American Journal of Physiology. 267: L489-97. PMID 7977760 DOI: 10.1152/ajplung.1994.267.5.L489  0.418
1994 DiCosmo BF, Geba GP, Picarella D, Elias JA, Rankin JA, Stripp BR, Whitsett JA, Flavell RA. Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity. The Journal of Clinical Investigation. 94: 2028-35. PMID 7962549 DOI: 10.1172/Jci117556  0.324
1994 Yei S, Mittereder N, Wert S, Whitsett JA, Wilmott RW, Trapnell BC. In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung. Human Gene Therapy. 5: 731-44. PMID 7948135 DOI: 10.1089/Hum.1994.5.6-731  0.379
1994 Mittereder N, Yei S, Bachurski C, Cuppoletti J, Whitsett JA, Tolstoshev P, Trapnell BC. Evaluation of the efficacy and safety of in vitro, adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA. Human Gene Therapy. 5: 717-29. PMID 7948134 DOI: 10.1089/hum.1994.5.6-717  0.308
1994 Ikeda K, Clark JC, Bachurski CJ, Wikenheiser KA, Cuppoletti J, Mohanti S, Morris RE, Whitsett JA. Immortalization of subpopulations of respiratory epithelial cells from transgenic mice bearing SV40 large T antigen. The American Journal of Physiology. 267: L309-17. PMID 7524342 DOI: 10.1152/ajplung.1994.267.3.L309  0.393
1993 Bohinski RJ, Huffman JA, Whitsett JA, Lattier DL. Cis-active elements controlling lung cell-specific expression of human pulmonary surfactant protein B gene Journal of Biological Chemistry. 268: 11160-11166. PMID 8496176  0.465
1993 Wert SE, Glasser SW, Korfhagen TR, Whitsett JA. Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Developmental Biology. 156: 426-43. PMID 8462742 DOI: 10.1006/dbio.1993.1090  0.352
1993 Baughman RP, Sternberg RI, Hull W, Buchsbaum JA, Whitsett J. Decreased surfactant protein A in patients with bacterial pneumonia American Review of Respiratory Disease. 147: 653-657. PMID 8442601 DOI: 10.1164/Ajrccm/147.3.653  0.325
1993 Sawaya PL, Stripp BR, Whitsett JA, Luse DS. The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families. Molecular and Cellular Biology. 13: 3860-71. PMID 8321193 DOI: 10.1128/Mcb.13.7.3860  0.338
1992 Gerdes J, Whitsett J, Long W. Elastase activity and surfactant protein concentration in tracheal aspirates from neonates receiving synthetic surfactant The Journal of Pediatrics. 120. PMID 1735850 DOI: 10.1016/S0022-3476(05)81231-4  0.346
1992 Wikenheiser KA, Wert SE, Wispé JR, Stahlman M, D'Amore-Bruno M, Singh G, Katyal SL, Whitsett JA. Distinct effects of oxygen on surfactant protein B expression in bronchiolar and alveolar epithelium. The American Journal of Physiology. 262: L32-9. PMID 1733279 DOI: 10.1152/ajplung.1992.262.1.L32  0.316
1992 Stripp BR, Sawaya PL, Luse DS, Wikenheiser KA, Wert SE, Huffman JA, Lattier DL, Singh G, Katyal SL, Whitsett JA. cis-acting elements that confer lung epithelial cell expression of the CC10 gene. The Journal of Biological Chemistry. 267: 14703-12. PMID 1634515  0.435
1992 Plopper CG, St. George JA, Read LC, Nishio SJ, Weir AJ, Edwards L, Tarantal AF, Pinkerton KE, Merritt TA, Whitsett JA, George-Nascimento C, Styne D. Acceleration of alveolar type II cell differentiation in fetal rhesus monkey lung by administration of EGF American Journal of Physiology - Lung Cellular and Molecular Physiology. 262. PMID 1550255 DOI: 10.1152/Ajplung.1992.262.3.L313  0.356
1992 Stahlman MT, Gray ME, Whitsett JA. The ontogeny and distribution of surfactant protein B in human fetuses and newborns. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 40: 1471-80. PMID 1527371  0.32
1992 Korfhagen TR, Bruno MD, Glasser SW, Ciraolo PJ, Whitsett JA, Lattier DL, Wikenheiser KA, Clark JC. Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity. The American Journal of Physiology. 263: L546-54. PMID 1443158 DOI: 10.1152/ajplung.1992.263.5.L546  0.37
1992 Wikenheiser KA, Stahlman MT, Ilona Linnoila R, Whitsett JA, Clark JC. Simian Virus 40 Large T Antigen Directed by Transcriptional Elements of the Human Surfactant Protein C Gene Produces Pulmonary Adenocarcinomas in Transgenic Mice Cancer Research. 52: 5342-5352. PMID 1394139  0.377
1991 Weaver TE, Whitsett JA. Function and regulation of expression of pulmonary surfactant-associated proteins Biochemical Journal. 273: 249-264. PMID 1991023  0.316
1991 Glasser SW, Korfhagen TR, Wert SE, Bruno MD, McWilliams KM, Vorbroker DK, Whitsett JA. Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice. The American Journal of Physiology. 261: L349-56. PMID 1928370 DOI: 10.1152/ajplung.1991.261.4.L349  0.382
1990 Slavkin HC, Johnson R, Oliver P, Bringas P, Don-Wheeler G, Mayo M, Whitsett JA. Lamellar body formation precedes pulmonary surfactant apoprotein expression during embryonic mouse lung development in vivo and in vitro. Differentiation; Research in Biological Diversity. 41: 223-36. PMID 2558940 DOI: 10.1111/j.1432-0436.1989.tb00751.x  0.435
1990 Korfhagen TR, Glasser SW, Wert SE, Bruno MD, Daugherty CC, McNeish JD, Stock JL, Potter SS, Whitsett JA. Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 87: 6122-6. PMID 2385587 DOI: 10.1073/pnas.87.16.6122  0.466
1990 Farrell PM, Bourbon JR, Notter RH, Marin L, Nogee LM, Whitsett JA. Relationships among surfactant fraction lipids, proteins and biophysical properties in the developing rat lung. Biochimica Et Biophysica Acta. 1044: 84-90. PMID 2340311 DOI: 10.1016/0005-2760(90)90222-J  0.339
1988 O'Reilly MA, Gazdar AF, Morris RE, Whitsett JA. Differential effects of glucocorticoid on expression of surfactant proteins in a human lung adenocarcinoma cell line. Biochimica Et Biophysica Acta. 970: 194-204. PMID 3382698 DOI: 10.1016/0167-4889(88)90179-6  0.316
1987 Notter RH, Shapiro DL, Ohning B, Whitsett JA. Biophysical activity of synthetic phospholipids combined with purified lung surfactant 6000 dalton apoprotein. Chemistry and Physics of Lipids. 44: 1-17. PMID 3607971 DOI: 10.1016/0009-3084(87)90002-8  0.302
1986 Weaver TE, Ross G, Daugherty C, Whitsett JA. Synthesis of surfactant-associated protein, 35,000 daltons, in fetal lung. Journal of Applied Physiology (Bethesda, Md. : 1985). 61: 694-700. PMID 2875055 DOI: 10.1152/jappl.1986.61.2.694  0.305
1985 Rice WR, Singleton FM, Whitsett J. 304 Regulation Of Surfactant Secretion From Isolated Type Ii Cells By Low Molecular Weight Polycations Pediatric Research. 19: 161-161. DOI: 10.1203/00006450-198504000-00334  0.304
1985 Nogee L, Dion C, Lorow D, Whitsett J. 296 In Vitro Synthesis Of Surfactant Associated Apolipoprotein A: Developmental Aspects Pediatric Research. 19. DOI: 10.1203/00006450-198504000-00326  0.421
1985 Daugherty C, Dion C, Whitsett J. 253 Organotypic Cultures Of Rat Pulmonary Epithelial Cells: Morphologic Differentiation Pediatric Research. 19: 153-153. DOI: 10.1203/00006450-198504000-00283  0.403
1984 Whitsett JA, Lessard J. APPEARANCE OF c-AMP DEPENDENT ACTIN PHOSPHORYLATION IN RAT LUNG AND TYPE II EPITHELIAL CELLS Pediatric Research. 18: 147A-147A. DOI: 10.1203/00006450-198404001-00326  0.311
1983 Whitsett JA, Darovec-Beckerman C, Rice WR. Ontogeny of adenylate cyclase activity in the rat lung: Guanine nucleotides and cytosolic factors Pediatric Research. 17: 553-561. PMID 6312401  0.342
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