April D. Pyle - Publications

Affiliations: 
Molecular Biology 0573 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Cell Biology, Human Development

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Romero MA, Pyle AD. 'Enhancing' skeletal muscle and stem cells in three-dimensional: genome regulation of skeletal muscle in development and disease. Current Opinion in Genetics & Development. 83: 102133. PMID 37951138 DOI: 10.1016/j.gde.2023.102133  0.376
2023 Hicks MR, Saleh KK, Clock B, Gibbs DE, Yang M, Younesi S, Gane L, Gutierrez-Garcia V, Xi H, Pyle AD. Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells. Nature Cell Biology. PMID 37919520 DOI: 10.1038/s41556-023-01271-0  0.491
2023 Jaime OG, Arias J, Pavani S, Pyle AD, Hicks MR. SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs. Development (Cambridge, England). PMID 37366057 DOI: 10.1242/dev.201509  0.41
2023 Stearns-Reider KM, Hicks MR, Hammond KG, Reynolds JC, Maity A, Kurmangaliyev YZ, Chin J, Stieg AZ, Geisse NA, Hohlbauch S, Kaemmer S, Schmitt LR, Pham TT, Yamauchi K, Novitch BG, ... ... Pyle AD, et al. Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis. Npj Regenerative Medicine. 8: 16. PMID 36922514 DOI: 10.1038/s41536-023-00287-2  0.345
2022 Wei Y, Qin Q, Yan C, Hayes MN, Garcia SP, Xi H, Do D, Jin AH, Eng TC, McCarthy KM, Adhikari A, Onozato ML, Spentzos D, Neilsen GP, Iafrate AJ, ... ... Pyle AD, et al. Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma. Nature Cancer. PMID 35982179 DOI: 10.1038/s43018-022-00414-w  0.394
2022 Hicks MR, Pyle AD. The emergence of the stem cell niche. Trends in Cell Biology. PMID 35934562 DOI: 10.1016/j.tcb.2022.07.003  0.508
2022 Chien P, Xi H, Pyle AD. Recapitulating human myogenesis ex vivo using human pluripotent stem cells. Experimental Cell Research. 411: 112990. PMID 34973262 DOI: 10.1016/j.yexcr.2021.112990  0.511
2021 Nitzahn M, Truong B, Khoja S, Vega-Crespo A, Le C, Eliav A, Makris G, Pyle AD, Häberle J, Lipshutz GS. CRISPR-Mediated Genomic Addition to CPS1 Deficient iPSCs is Insufficient to Restore Nitrogen Homeostasis. The Yale Journal of Biology and Medicine. 94: 545-557. PMID 34970092  0.486
2021 Petrigliano FA, Liu NQ, Lee S, Tassey J, Sarkar A, Lin Y, Li L, Yu Y, Geng D, Zhang J, Shkhyan R, Bogdanov J, Van Handel B, Ferguson GB, Lee Y, ... ... Pyle AD, et al. Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes. Npj Regenerative Medicine. 6: 77. PMID 34815400 DOI: 10.1038/s41536-021-00187-3  0.316
2020 Xi H, Young CS, Pyle AD. Generation of PAX7 Reporter Cells to Investigate Skeletal Myogenesis from Human Pluripotent Stem Cells. Star Protocols. 1: 100158. PMID 33377052 DOI: 10.1016/j.xpro.2020.100158  0.494
2020 Sengupta K, Mishra MK, Loro E, Spencer MJ, Pyle AD, Khurana TS. Genome Editing-Mediated Utrophin Upregulation in Duchenne Muscular Dystrophy Stem Cells. Molecular Therapy. Nucleic Acids. 22: 500-509. PMID 33230452 DOI: 10.1016/J.Omtn.2020.08.031  0.309
2020 Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, ... ... Pyle AD, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 27: 181-185. PMID 32619514 DOI: 10.1016/j.stem.2020.06.006  0.506
2020 Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, ... ... Pyle AD, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. PMID 32396864 DOI: 10.1016/J.Stem.2020.04.017  0.57
2019 Mosich GM, Husman R, Shah P, Sharma A, Ressadeh K, Aderibigbe T, Hu VJ, McClintick DJ, Wu G, Gatto JD, Xi H, Pyle AD, Péault B, Petrigliano FA, Dar A. Non-fibro-adipogenic pericytes from human embryonic stem cells attenuate degeneration of the chronically injured mouse muscle. Jci Insight. 4. PMID 31852842 DOI: 10.1172/Jci.Insight.125334  0.446
2019 Xi H, Pyle A. Beyond the genome: RNA control of stem cells. Science (New York, N.Y.). 366: 684-685. PMID 31699921 DOI: 10.1126/Science.Aaz4859  0.426
2019 Bellmann J, Goswami RY, Girardo S, Rein N, Hosseinzadeh Z, Hicks MR, Busskamp V, Pyle AD, Werner C, Sterneckert J. A customizable microfluidic platform for medium-throughput modeling of neuromuscular circuits. Biomaterials. 225: 119537. PMID 31614290 DOI: 10.1016/J.Biomaterials.2019.119537  0.454
2019 Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Research & Therapy. 10: 52. PMID 30755264 DOI: 10.1186/S13287-019-1147-7  0.409
2018 Ferguson GB, Van Handel B, Bay M, Fiziev P, Org T, Lee S, Shkhyan R, Banks NW, Scheinberg M, Wu L, Saitta B, Elphingstone J, Larson AN, Riester SM, Pyle AD, et al. Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes. Nature Communications. 9: 3634. PMID 30194383 DOI: 10.1038/S41467-018-05573-Y  0.502
2017 Hicks MR, Hiserodt J, Paras K, Fujiwara W, Eskin A, Jan M, Xi H, Young CS, Evseenko D, Nelson SF, Spencer MJ, Handel BV, Pyle AD. ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs. Nature Cell Biology. PMID 29255171 DOI: 10.1038/S41556-017-0010-2  0.561
2017 Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Research & Therapy. 8: 217. PMID 28969679 DOI: 10.1186/S13287-017-0652-9  0.5
2017 Young CS, Mokhonova E, Quinonez M, Pyle AD, Spencer MJ. Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy. Journal of Neuromuscular Diseases. PMID 28505980 DOI: 10.3233/Jnd-170218  0.336
2017 Xi H, Fujiwara W, Gonzalez K, Jan M, Liebscher S, Van Handel B, Schenke-Layland K, Pyle AD. In Vivo Human Somitogenesis Guides Somite Development from hPSCs. Cell Reports. 18: 1573-1585. PMID 28178531 DOI: 10.1016/J.Celrep.2017.01.040  0.528
2016 Lee PC, Truong B, Vega-Crespo A, Gilmore WB, Hermann K, Angarita SA, Tang JK, Chang KM, Wininger AE, Lam AK, Schoenberg BE, Cederbaum SD, Pyle AD, Byrne JA, Lipshutz GS. Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. Molecular Therapy. Nucleic Acids. 5: e394. PMID 28131247 DOI: 10.1038/mtna.2016.98  0.469
2016 Lee PC, Truong B, Vega-Crespo A, Gilmore WB, Hermann K, Angarita SA, Tang JK, Chang KM, Wininger AE, Lam AK, Schoenberg BE, Cederbaum SD, Pyle AD, Byrne JA, Lipshutz GS. Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. Molecular Therapy. Nucleic Acids. 5: e394. PMID 27898091 DOI: 10.1038/Mtna.2016.98  0.554
2016 Young CS, Hicks MR, Ermolova NV, Nakano H, Jan M, Younesi S, Karumbayaram S, Kumagai-Cresse C, Wang D, Zack JA, Kohn DB, Nakano A, Nelson SF, Miceli MC, Spencer MJ, ... Pyle AD, et al. A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells. Cell Stem Cell. PMID 26877224 DOI: 10.1016/J.Stem.2016.01.021  0.364
2016 Young CS, Hicks MR, Ermolova NV, Nakano H, Jan M, Younesi S, Nakano A, Nelson SF, Miceli MC, Spencer MJ, Pyle AD. 735. Functional Restoration of Dystrophin Protein in HiPSC-Derived Skeletal Myotubes and Cardiomyocytes After CRISPR/Cas9-Mediated Deletion of 530-725kb of DMD Molecular Therapy. 24: S290. DOI: 10.1016/S1525-0016(16)33543-2  0.425
2015 Thakore-Shah K, Koleilat T, Jan M, John A, Pyle AD. REST/NRSF Knockdown Alters Survival, Lineage Differentiation and Signaling in Human Embryonic Stem Cells. Plos One. 10: e0145280. PMID 26690059 DOI: 10.1371/Journal.Pone.0145280  0.759
2015 Hicks M, Pyle A. The Path from Pluripotency to Skeletal Muscle: Developmental Myogenesis Guides the Way. Cell Stem Cell. 17: 255-7. PMID 26340524 DOI: 10.1016/J.Stem.2015.08.017  0.505
2015 Hou S, Choi JS, Chen KJ, Zhang Y, Peng J, Garcia MA, Yu JH, Thakore-Shah K, Ro T, Chen JF, Peyda P, Fan G, Pyle AD, Wang H, Tseng HR. Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of Mammalian cells. Small (Weinheim An Der Bergstrasse, Germany). 11: 2499-504. PMID 25613059 DOI: 10.1002/Smll.201402602  0.742
2014 Peng J, Garcia MA, Choi JS, Zhao L, Chen KJ, Bernstein JR, Peyda P, Hsiao YS, Liu KW, Lin WY, Pyle AD, Wang H, Hou S, Tseng HR. Molecular recognition enables nanosubstrate-mediated delivery of gene-encapsulated nanoparticles with high efficiency. Acs Nano. 8: 4621-9. PMID 24708312 DOI: 10.1021/Nn5003024  0.317
2013 Jonas SJ, Alva JA, Richardson W, Sherman SP, Galic Z, Pyle AD, Dunn B. A spatially and chemically defined platform for the uniform growth of human pluripotent stem cells. Materials Science & Engineering. C, Materials For Biological Applications. 33: 234-41. PMID 25428067 DOI: 10.1016/J.Msec.2012.08.035  0.79
2013 Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, et al. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Research & Therapy. 4: 87. PMID 23890092 DOI: 10.1186/Scrt246  0.549
2013 Sherman SP, Pyle AD. Small molecule screening with laser cytometry can be used to identify pro-survival molecules in human embryonic stem cells. Plos One. 8: e54948. PMID 23383009 DOI: 10.1371/Journal.Pone.0054948  0.811
2013 Tran T, Andersen R, Sherman SP, Pyle AD. Insights into skeletal muscle development and applications in regenerative medicine. International Review of Cell and Molecular Biology. 300: 51-83. PMID 23273859 DOI: 10.1016/B978-0-12-405210-9.00002-3  0.765
2013 Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B. Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. Journal of Virology. 87: 2094-108. PMID 23192877 DOI: 10.1128/Jvi.02032-12  0.777
2013 Yanes RE, Tarn D, Hwang AA, Ferris DP, Sherman SP, Thomas CR, Lu J, Pyle AD, Zink JI, Tamanoi F. Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition. Small (Weinheim An Der Bergstrasse, Germany). 9: 697-704. PMID 23152124 DOI: 10.1002/Smll.201201811  0.708
2013 Palomares K, Vigant F, Handel BV, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HKA, Morizono K, Pyle AD, Lee B. Authors correction to Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinb2-positive stem cell populations In vitro and bypass the liver sink when administered In vivo [Journal of Virology, 87, 4, (2013) 2094 2108] Journal of Virology. 87: 4794. DOI: 10.1128/JVI.00279-13  0.76
2012 Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Translational Medicine. 1: 36-43. PMID 23197638 DOI: 10.5966/Sctm.2011-0001  0.504
2011 Alva JA, Lee GE, Escobar EE, Pyle AD. Phosphatase and tensin homolog regulates the pluripotent state and lineage fate choice in human embryonic stem cells. Stem Cells (Dayton, Ohio). 29: 1952-62. PMID 21948699 DOI: 10.1002/Stem.748  0.563
2011 Sherman SP, Alva JA, Thakore-Shah K, Pyle AD. Human pluripotent stem cells: the development of high-content screening strategies. Methods in Molecular Biology (Clifton, N.J.). 767: 283-95. PMID 21822883 DOI: 10.1007/978-1-61779-201-4_21  0.721
2011 Le Belle JE, Orozco NM, Paucar AA, Saxe JP, Mottahedeh J, Pyle AD, Wu H, Kornblum HI. Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell. 8: 59-71. PMID 21211782 DOI: 10.1016/J.Stem.2010.11.028  0.497
2011 Kamei Ki, Ohashi M, Graham NA, Chen Y, Clark AT, Witte ON, Graeber TG, Pyle AD, Tseng HR. Quantitative cytological feature analysis by microfluidic image cytometry reveals phenotypic differences among human pluripotent stem cell lines 15th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2011, Microtas 2011. 1: 148-150.  0.407
2010 Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 7: 329-42. PMID 20727844 DOI: 10.1016/J.Stem.2010.06.024  0.771
2010 Tseng HC, Arasteh A, Paranjpe A, Teruel A, Yang W, Behel A, Alva JA, Walter G, Head C, Ishikawa TO, Herschman HR, Cacalano N, Pyle AD, Park NH, Jewett A. Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells. Plos One. 5: e11590. PMID 20661281 DOI: 10.1371/Journal.Pone.0011590  0.591
2010 Kamei K, Ohashi M, Gschweng E, Ho Q, Suh J, Tang J, For Yu ZT, Clark AT, Pyle AD, Teitell MA, Lee KB, Witte ON, Tseng HR. Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions. Lab On a Chip. 10: 1113-9. PMID 20390128 DOI: 10.1039/B922884E  0.463
2009 Zeng W, de Greef JC, Chen YY, Chien R, Kong X, Gregson HC, Winokur ST, Pyle A, Robertson KD, Schmiesing JA, Kimonis VE, Balog J, Frants RR, Ball AR, Lock LF, et al. Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). Plos Genetics. 5: e1000559. PMID 19593370 DOI: 10.1371/Journal.Pgen.1000559  0.333
2009 Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, ... ... Pyle AD, et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 5: 111-23. PMID 19570518 DOI: 10.1016/J.Stem.2009.06.008  0.525
2009 Conway AE, Lindgren A, Galic Z, Pyle AD, Wu H, Zack JA, Pelligrini M, Teitell MA, Clark AT. A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors. Stem Cells (Dayton, Ohio). 27: 18-28. PMID 19224508 DOI: 10.1634/Stemcells.2008-0529  0.505
2009 Damoiseaux R, Sherman SP, Alva JA, Peterson C, Pyle AD. Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 533-42. PMID 19074420 DOI: 10.1634/Stemcells.2008-0596  0.804
2008 Wu H, Kim KJ, Mehta K, Paxia S, Sundstrom A, Anantharaman T, Kuraishy AI, Doan T, Ghosh J, Pyle AD, Clark A, Lowry W, Fan G, Baxter T, Mishra B, et al. Copy number variant analysis of human embryonic stem cells. Stem Cells (Dayton, Ohio). 26: 1484-9. PMID 18369100 DOI: 10.1634/Stemcells.2007-0993  0.461
2008 Hohenstein KA, Pyle AD, Chern JY, Lock LF, Donovan PJ. Nucleofection mediates high-efficiency stable gene knockdown and transgene expression in human embryonic stem cells. Stem Cells (Dayton, Ohio). 26: 1436-43. PMID 18323409 DOI: 10.1634/Stemcells.2007-0857  0.593
2008 Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 2883-8. PMID 18287077 DOI: 10.1073/Pnas.0711983105  0.615
2006 Fenderson BA, De Miguel MP, Pyle AD, Donovan PJ. Staining embryonic stem cells using monoclonal antibodies to stage-specific embryonic antigens. Methods in Molecular Biology (Clifton, N.J.). 325: 207-24. PMID 16761728 DOI: 10.1385/1-59745-005-7:207  0.567
2006 Pyle AD, Lock LF, Donovan PJ. Neurotrophins mediate human embryonic stem cell survival. Nature Biotechnology. 24: 344-50. PMID 16444268 DOI: 10.1038/Nbt1189  0.541
2005 Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1489-501. PMID 16002782 DOI: 10.1634/Stemcells.2005-0034  0.528
2004 Pyle AD, Donovan PJ, Lock LF. Chipping away at 'stemness'. Genome Biology. 5: 235. PMID 15287966 DOI: 10.1186/Gb-2004-5-8-235  0.578
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