Curt M. Horvath - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Philips RL, Wang Y, Cheon H, Kanno Y, Gadina M, Sartorelli V, Horvath CM, Darnell JE, Stark GR, O'Shea JJ. The JAK-STAT pathway at 30: Much learned, much more to do. Cell. 185: 3857-3876. PMID 36240739 DOI: 10.1016/j.cell.2022.09.023  0.372
2021 Parisien JP, Lenoir JJ, Alvarado G, Horvath CM. The Human STAT2 Coiled-Coil Domain Contains a Degron for Zika Virus Interferon Evasion. Journal of Virology. JVI0130121. PMID 34643427 DOI: 10.1128/JVI.01301-21  0.528
2019 Quicke KM, Kim KY, Horvath CM, Suthar MS. RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 31237466 DOI: 10.1089/Jir.2019.0059  0.551
2018 Au-Yeung N, Horvath CM. Transcriptional and chromatin regulation in interferon and innate antiviral gene expression. Cytokine & Growth Factor Reviews. 44: 11-17. PMID 30509403 DOI: 10.1016/J.Cytogfr.2018.10.003  0.536
2018 Saleiro D, Blyth GT, Kosciuczuk EM, Ozark PA, Majchrzak-Kita B, Arslan AD, Fischietti M, Reddy NK, Horvath CM, Davis RJ, Fish EN, Platanias LC. IFN-γ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5. Science Signaling. 11. PMID 30459284 DOI: 10.1126/Scisignal.Aap9921  0.521
2018 Mandhana R, Horvath CM. Sendai Virus Infection Induces Expression of Novel RNAs in Human Cells. Scientific Reports. 8: 16815. PMID 30429577 DOI: 10.1038/S41598-018-35231-8  0.5
2018 Au-Yeung N, Horvath CM. Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2. Iscience. 6: 68-82. PMID 30240626 DOI: 10.1016/J.Isci.2018.07.013  0.44
2018 Mandhana R, Qian LK, Horvath CM. Constitutively Active MDA5 Proteins Are Inhibited by Paramyxovirus V Proteins. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 38: 319-332. PMID 30130154 DOI: 10.1089/Jir.2018.0049  0.555
2018 Parisien JP, Lenoir JJ, Mandhana R, Rodriguez KR, Qian K, Bruns AM, Horvath CM. RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling. Embo Reports. PMID 29661858 DOI: 10.15252/Embr.201745176  0.605
2017 Pollpeter D, Parsons M, Sobala AE, Coxhead S, Lang RD, Bruns AM, Papaioannou S, McDonnell JM, Apolonia L, Chowdhury JA, Horvath CM, Malim MH. Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G. Nature Microbiology. PMID 29158605 DOI: 10.1038/S41564-017-0063-9  0.394
2016 Komuro A, Homma Y, Negoro T, Barber GN, Horvath CM. The TAR-RNA binding protein is required for immunoresponces triggered by Cardiovirus infection. Biochemical and Biophysical Research Communications. PMID 27743889 DOI: 10.1016/J.Bbrc.2016.10.023  0.496
2015 Gale M, Horvath CM. Editorial overview: Antiviral strategies. Current Opinion in Virology. 12: v-vii. PMID 26004174 DOI: 10.1016/J.Coviro.2015.05.001  0.304
2015 Bruns AM, Horvath CM. LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling. Cytokine. 74: 198-206. PMID 25794939 DOI: 10.1016/J.Cyto.2015.02.010  0.582
2015 Horvath CM. A serpin takes a bite out of the flu. Cell Host & Microbe. 17: 283-4. PMID 25766286 DOI: 10.1016/J.Chom.2015.02.018  0.345
2015 Horvath C. ID: 82 Cytokine. 76: 63. DOI: 10.1016/J.Cyto.2015.08.035  0.577
2014 Tell RW, Horvath CM. Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: 12787-92. PMID 25139989 DOI: 10.1073/Pnas.1404881111  0.352
2014 Bruns AM, Leser GP, Lamb RA, Horvath CM. The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly. Molecular Cell. 55: 771-81. PMID 25127512 DOI: 10.1016/J.Molcel.2014.07.003  0.459
2014 Bruns AM, Horvath CM. Antiviral RNA recognition and assembly by RLR family innate immune sensors. Cytokine & Growth Factor Reviews. 25: 507-12. PMID 25081315 DOI: 10.1016/J.Cytogfr.2014.07.006  0.546
2014 Rodriguez KR, Bruns AM, Horvath CM. MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction. Journal of Virology. 88: 8194-200. PMID 24850739 DOI: 10.1128/Jvi.00640-14  0.585
2014 Rodriguez KR, Horvath CM. Paramyxovirus V protein interaction with the antiviral sensor LGP2 disrupts MDA5 signaling enhancement but is not relevant to LGP2-mediated RLR signaling inhibition. Journal of Virology. 88: 8180-8. PMID 24829334 DOI: 10.1128/Jvi.00737-14  0.617
2014 Freaney JE, Zhang Q, Yigit E, Kim R, Widom J, Wang JP, Horvath CM. High-density nucleosome occupancy map of human chromosome 9p21-22 reveals chromatin organization of the type I interferon gene cluster. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 676-85. PMID 24673249 DOI: 10.1089/Jir.2013.0118  0.347
2013 Buggele WA, Krause KE, Horvath CM. Small RNA profiling of influenza A virus-infected cells identifies miR-449b as a regulator of histone deacetylase 1 and interferon beta. Plos One. 8: e76560. PMID 24086750 DOI: 10.1371/Journal.Pone.0076560  0.417
2013 Au-Yeung N, Mandhana R, Horvath CM. Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway. Jak-Stat. 2: e23931. PMID 24069549 DOI: 10.4161/jkst.23931  0.439
2013 Freaney JE, Kim R, Mandhana R, Horvath CM. Extensive cooperation of immune master regulators IRF3 and NFκB in RNA Pol II recruitment and pause release in human innate antiviral transcription. Cell Reports. 4: 959-73. PMID 23994473 DOI: 10.1016/J.Celrep.2013.07.043  0.512
2013 Buggele WA, Horvath CM. MicroRNA profiling of Sendai virus-infected A549 cells identifies miR-203 as an interferon-inducible regulator of IFIT1/ISG56. Journal of Virology. 87: 9260-70. PMID 23785202 DOI: 10.1128/Jvi.01064-13  0.413
2013 Light WH, Freaney J, Sood V, Thompson A, D'Urso A, Horvath CM, Brickner JH. A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory. Plos Biology. 11: e1001524. PMID 23555195 DOI: 10.1371/Journal.Pbio.1001524  0.416
2013 Parisien JP, Horvath CM. Detection of activated STAT proteins. Methods in Molecular Biology (Clifton, N.J.). 967: 135-45. PMID 23296726 DOI: 10.1007/978-1-62703-242-1_9  0.55
2013 Rodriguez KR, Horvath CM. Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I. Journal of Virology. 87: 2974-8. PMID 23269789 DOI: 10.1128/Jvi.02843-12  0.454
2013 Bruns AM, Pollpeter D, Hadizadeh N, Myong S, Marko JF, Horvath CM. ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2). The Journal of Biological Chemistry. 288: 938-46. PMID 23184951 DOI: 10.1074/Jbc.M112.424416  0.483
2013 Freaney JE, Kim R, Horvath CM. 84 Cytokine. 63: 263. DOI: 10.1016/J.Cyto.2013.06.087  0.497
2012 Buggele WA, Johnson KE, Horvath CM. Influenza A virus infection of human respiratory cells induces primary microRNA expression. The Journal of Biological Chemistry. 287: 31027-40. PMID 22822053 DOI: 10.1074/Jbc.M112.387670  0.377
2012 Bruns AM, Horvath CM. Activation of RIG-I-like receptor signal transduction. Critical Reviews in Biochemistry and Molecular Biology. 47: 194-206. PMID 22066529 DOI: 10.3109/10409238.2011.630974  0.544
2012 Bruns A, Pollpeter D, Hadizadeh N, Myong S, Marko J, Horvath C. P143 Single molecule analysis of the RIG-I-like receptor, LGP2 Cytokine. 59: 566. DOI: 10.1016/J.Cyto.2012.06.243  0.402
2012 Horvath C. P124 Transcriptional regulation of the human type I IFN locus Cytokine. 59: 559. DOI: 10.1016/J.Cyto.2012.06.216  0.527
2012 Horvath CM. Activation and inhibition of JAK-STAT signal transduction by RNA viruses Jak-Stat Signaling: From Basics to Disease. 371-385. DOI: 10.1007/978-3-7091-0891-8_20  0.598
2011 Pollpeter D, Komuro A, Barber GN, Horvath CM. Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein. Plos One. 6: e18842. PMID 21533147 DOI: 10.1371/Journal.Pone.0018842  0.553
2011 Horvath CM, Buggele W, Johnson K. CS01-7 Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression Cytokine. 56: 5. DOI: 10.1016/J.Cyto.2011.07.306  0.383
2010 Ramachandran A, Horvath CM. Dissociation of paramyxovirus interferon evasion activities: universal and virus-specific requirements for conserved V protein amino acids in MDA5 interference. Journal of Virology. 84: 11152-63. PMID 20719949 DOI: 10.1128/Jvi.01375-10  0.577
2010 Pollpeter D, Komuro A, Barber GN, Horvath CM. PS3-13 A role for the DEXH box protein LGP2 in innate immune responses induced by cytosolic DNA and Listeria monocytogenes Cytokine. 52: 84-85. DOI: 10.1016/J.Cyto.2010.07.352  0.383
2010 Horvath CM. SS10-1 Activation and inhibition of interferon signaling and antiviral responses by RNA viruses Cytokine. 52: 78. DOI: 10.1016/J.Cyto.2010.07.323  0.494
2010 Ramachandran A, Parisien J, Horvath CM. PS2-74 Molecular identification of MDA5 and STAT2 binding site for measles virus V protein Cytokine. 52: 65-66. DOI: 10.1016/J.Cyto.2010.07.279  0.521
2010 Parisien J, Bamming D, Komuro A, Ramachandran A, Rodriguez JJ, Barber G, Wojahn RD, Horvath CM. PS2-63 A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2 Cytokine. 52: 63. DOI: 10.1016/J.Cyto.2010.07.268  0.702
2010 Schroeder A, Horvath C. PS2-62 Differential STAT targeting by paramyxovirus V proteins Cytokine. 52: 63. DOI: 10.1016/J.Cyto.2010.07.267  0.486
2010 Freaney JE, Horvath CM. PS2-40 Transcriptional regulation of the human Type I IFN gene cluster Cytokine. 52: 58-59. DOI: 10.1016/J.Cyto.2010.07.245  0.375
2010 Buggele WA, Horvath CM. PS2-32 MicroRNA regulation in response to human influenza virus infection Cytokine. 52: 57. DOI: 10.1016/J.Cyto.2010.07.237  0.423
2010 Johnson KE, Horvath CM. PS2-31 Host MicroRNA regulation during influenza virus infection Cytokine. 52: 56-57. DOI: 10.1016/J.Cyto.2010.07.236  0.41
2009 Massich MD, Giljohann DA, Seferos DS, Ludlow LE, Horvath CM, Mirkin CA. Regulating immune response using polyvalent nucleic acid-gold nanoparticle conjugates. Molecular Pharmaceutics. 6: 1934-40. PMID 19810673 DOI: 10.1021/Mp900172M  0.311
2009 Ramachandran A, Horvath CM. Paramyxovirus disruption of interferon signal transduction: STATus report. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 531-7. PMID 19694544 DOI: 10.1089/Jir.2009.0070  0.595
2009 Parisien JP, Bamming D, Komuro A, Ramachandran A, Rodriguez JJ, Barber G, Wojahn RD, Horvath CM. A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2. Journal of Virology. 83: 7252-60. PMID 19403670 DOI: 10.1128/Jvi.00153-09  0.814
2009 Puri M, Lemon K, Duprex WP, Rima BK, Horvath CM. A point mutation, E95D, in the mumps virus V protein disengages STAT3 targeting from STAT1 targeting. Journal of Virology. 83: 6347-56. PMID 19386700 DOI: 10.1128/Jvi.00596-09  0.643
2009 Bamming D, Horvath CM. Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2. The Journal of Biological Chemistry. 284: 9700-12. PMID 19211564 DOI: 10.1074/Jbc.M807365200  0.546
2008 Komuro A, Bamming D, Horvath CM. Negative regulation of cytoplasmic RNA-mediated antiviral signaling. Cytokine. 43: 350-8. PMID 18703349 DOI: 10.1016/J.Cyto.2008.07.011  0.517
2008 Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. Embo Reports. 9: 930-6. PMID 18636086 DOI: 10.1038/Embor.2008.136  0.572
2008 Ramachandran A, Parisien JP, Horvath CM. STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition. Journal of Virology. 82: 8330-8. PMID 18579593 DOI: 10.1128/Jvi.00831-08  0.668
2008 Ludlow LE, Lo MK, Rodriguez JJ, Rota PA, Horvath CM. Henipavirus V protein association with Polo-like kinase reveals functional overlap with STAT1 binding and interferon evasion. Journal of Virology. 82: 6259-71. PMID 18417573 DOI: 10.1128/Jvi.00409-08  0.83
2008 Lu LL, Puri M, Horvath CM, Sen GC. Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1. The Journal of Biological Chemistry. 283: 14269-76. PMID 18362155 DOI: 10.1074/Jbc.M710089200  0.613
2008 Kraus TA, Garza L, Horvath CM. Enabled interferon signaling evasion in an immune-competent transgenic mouse model of parainfluenza virus 5 infection. Virology. 371: 196-205. PMID 17964629 DOI: 10.1016/J.Virol.2007.10.001  0.529
2008 Horvath CM. PL-19 Activation and inhibition of interferon and cytokine signaling by emerging pathogens Cytokine. 43: 303. DOI: 10.1016/J.Cyto.2008.07.333  0.466
2006 Komuro A, Horvath CM. RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2. Journal of Virology. 80: 12332-42. PMID 17020950 DOI: 10.1128/Jvi.01325-06  0.634
2006 Yount JS, Kraus TA, Horvath CM, Moran TM, López CB. A novel role for viral-defective interfering particles in enhancing dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 177: 4503-13. PMID 16982887 DOI: 10.4049/Jimmunol.177.7.4503  0.399
2006 Cruz CD, Palosaari H, Parisien JP, Devaux P, Cattaneo R, Ouchi T, Horvath CM. Measles virus V protein inhibits p53 family member p73. Journal of Virology. 80: 5644-50. PMID 16699046 DOI: 10.1128/Jvi.02400-05  0.574
2006 Nusinzon I, Horvath CM. Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. Molecular and Cellular Biology. 26: 3106-13. PMID 16581785 DOI: 10.1128/Mcb.26.8.3106-3113.2006  0.518
2006 Gu W, Nusinzon I, Smith RD, Horvath CM, Silverman RB. Carbonyl- and sulfur-containing analogs of suberoylanilide hydroxamic acid: Potent inhibition of histone deacetylases. Bioorganic & Medicinal Chemistry. 14: 3320-9. PMID 16434199 DOI: 10.1016/J.Bmc.2005.12.047  0.304
2005 Nusinzon I, Horvath CM. Unexpected roles for deacetylation in interferon- and cytokine-induced transcription. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 25: 745-8. PMID 16375602 DOI: 10.1089/Jir.2005.25.745  0.396
2005 Nusinzon I, Horvath CM. Histone deacetylases as transcriptional activators? Role reversal in inducible gene regulation. Science's Stke : Signal Transduction Knowledge Environment. 2005: re11. PMID 16091625 DOI: 10.1126/Stke.2962005Re11  0.422
2005 Ulane CM, Kentsis A, Cruz CD, Parisien JP, Schneider KL, Horvath CM. Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain. Journal of Virology. 79: 10180-9. PMID 16051811 DOI: 10.1128/Jvi.79.16.10180-10189.2005  0.853
2004 Horvath CM. Weapons of STAT destruction. Interferon evasion by paramyxovirus V protein. European Journal of Biochemistry / Febs. 271: 4621-8. PMID 15606749 DOI: 10.1111/J.1432-1033.2004.04425.X  0.685
2004 Horvath CM. The Jak-STAT pathway stimulated by interleukin 6. Science's Stke : Signal Transduction Knowledge Environment. 2004: tr9. PMID 15561981 DOI: 10.1126/Stke.2602004Tr9  0.477
2004 Horvath CM. The Jak-STAT pathway stimulated by interferon gamma. Science's Stke : Signal Transduction Knowledge Environment. 2004: tr8. PMID 15561980 DOI: 10.1126/Stke.2602004Tr8  0.534
2004 Horvath CM. The Jak-STAT pathway stimulated by interferon alpha or interferon beta. Science's Stke : Signal Transduction Knowledge Environment. 2004: tr10. PMID 15561979 DOI: 10.1126/Stke.2602004Tr10  0.518
2004 Rodriguez JJ, Horvath CM. Host evasion by emerging paramyxoviruses: Hendra virus and Nipah virus v proteins inhibit interferon signaling. Viral Immunology. 17: 210-9. PMID 15279700 DOI: 10.1089/0882824041310568  0.853
2004 Rodriguez JJ, Cruz CD, Horvath CM. Identification of the nuclear export signal and STAT-binding domains of the Nipah virus V protein reveals mechanisms underlying interferon evasion. Journal of Virology. 78: 5358-67. PMID 15113915 DOI: 10.1128/Jvi.78.10.5358-5367.2004  0.842
2004 Horvath CM. Silencing STATs: lessons from paramyxovirus interferon evasion. Cytokine & Growth Factor Reviews. 15: 117-27. PMID 15110796 DOI: 10.1016/J.Cytogfr.2004.02.003  0.648
2004 Horvath CM. Erratum to “Silencing STATs: lessons from paramyxovirus interferon evasion”[Cytokine Growth Factor Rev. 15 (2004) 117–127] Cytokine & Growth Factor Reviews. 15: 477-477. DOI: 10.1016/S1359-6101(04)00073-5  0.344
2004 Horvath CM. Erratum to “Silencing STATs: lessons from paramyxovirus interferon evasion” Cytokine & Growth Factor Reviews. 15: 477. DOI: 10.1016/J.Cytogfr.2004.08.001  0.509
2003 Nusinzon I, Horvath CM. Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1. Proceedings of the National Academy of Sciences of the United States of America. 100: 14742-7. PMID 14645718 DOI: 10.1073/Pnas.2433987100  0.5
2003 Rodriguez JJ, Wang LF, Horvath CM. Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulation. Journal of Virology. 77: 11842-5. PMID 14557668 DOI: 10.1128/Jvi.77.21.11842-11845.2003  0.848
2003 Zhu C, Rao K, Xiong H, Gagnidze K, Li F, Horvath C, Plevy S. Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP. The Journal of Biological Chemistry. 278: 39372-82. PMID 12876285 DOI: 10.1074/Jbc.M306441200  0.39
2003 Palosaari H, Parisien JP, Rodriguez JJ, Ulane CM, Horvath CM. STAT protein interference and suppression of cytokine signal transduction by measles virus V protein. Journal of Virology. 77: 7635-44. PMID 12805463 DOI: 10.1128/Jvi.77.13.7635-7644.2003  0.846
2003 Rogers RS, Horvath CM, Matunis MJ. SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation. The Journal of Biological Chemistry. 278: 30091-7. PMID 12764129 DOI: 10.1074/Jbc.M301344200  0.553
2003 Ulane CM, Rodriguez JJ, Parisien JP, Horvath CM. STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling. Journal of Virology. 77: 6385-93. PMID 12743296 DOI: 10.1128/Jvi.77.11.6385-6393.2003  0.845
2003 Kraus TA, Lau JF, Parisien JP, Horvath CM. A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response. The Journal of Biological Chemistry. 278: 13033-8. PMID 12574168 DOI: 10.1074/Jbc.M212972200  0.832
2003 Lau JF, Nusinzon I, Burakov D, Freedman LP, Horvath CM. Role of metazoan mediator proteins in interferon-responsive transcription. Molecular and Cellular Biology. 23: 620-8. PMID 12509459 DOI: 10.1128/Mcb.23.2.620-628.2003  0.799
2003 Rodriguez JJ, Wang LF, Horvath CM. Erratum: Hendra Virus V Protein Inhibits Interferon Signaling by Preventing STAT1 and STAT2 Nuclear Accumulation (Journal of Virology (2003) 77:21 (11842-11845)) Journal of Virology. 77. DOI: 10.1128/Jvi.77.24.13457.2003  0.835
2003 Aaronson DS, Horvath CM. The IFN-  Pathway Science Signaling. 2003: cm14-cm14. DOI: 10.1126/Stke.2003.197.Cm14  0.51
2003 Aaronson DS, Horvath CM. The STAT3 Pathway Science Signaling. 2003: cm13-cm13. DOI: 10.1126/Stke.2003.197.Cm13  0.498
2003 Aaronson DS, Horvath CM. The Type I Interferon Pathway Science Signaling. 2003: cm12-cm12. DOI: 10.1126/Stke.2003.197.Cm12  0.512
2003 Aaronson DS, Horvath CM. The JAK-STAT Pathway Science Signaling. 2003: cm11-cm11. DOI: 10.1126/Stke.2003.197.Cm11  0.504
2002 Ulane CM, Horvath CM. Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components. Virology. 304: 160-6. PMID 12504558 DOI: 10.1006/Viro.2002.1773  0.857
2002 Rodriguez JJ, Parisien JP, Horvath CM. Nipah virus V protein evades alpha and gamma interferons by preventing STAT1 and STAT2 activation and nuclear accumulation. Journal of Virology. 76: 11476-83. PMID 12388709 DOI: 10.1128/Jvi.76.22.11476-11483.2002  0.855
2002 Parisien JP, Lau JF, Horvath CM. STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication. Journal of Virology. 76: 6435-41. PMID 12050355 DOI: 10.1128/Jvi.76.13.6435-6441.2002  0.802
2002 Aaronson DS, Horvath CM. A road map for those who don't know JAK-STAT. Science (New York, N.Y.). 296: 1653-5. PMID 12040185 DOI: 10.1126/Science.1071545  0.466
2002 Lau JF, Horvath CM. Mechanisms of Type I interferon cell signaling and STAT-mediated transcriptional responses. The Mount Sinai Journal of Medicine, New York. 69: 156-68. PMID 12035075  0.821
2002 Parisien JP, Lau JF, Rodriguez JJ, Ulane CM, Horvath CM. Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2 but is independent of alpha/beta interferon signal transduction. Journal of Virology. 76: 4190-8. PMID 11932384 DOI: 10.1128/Jvi.76.9.4190-4198.2002  0.822
2002 Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P, García-Sastre A. Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. Journal of Virology. 76: 1206-12. PMID 11773396 DOI: 10.1128/Jvi.76.3.1206-1212.2002  0.587
2001 Myers MP, Andersen JN, Cheng A, Tremblay ML, Horvath CM, Parisien JP, Salmeen A, Barford D, Tonks NK. TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B. The Journal of Biological Chemistry. 276: 47771-4. PMID 11694501 DOI: 10.1074/Jbc.C100583200  0.414
2001 Ivanov VN, Bhoumik A, Krasilnikov M, Raz R, Owen-Schaub LB, Levy D, Horvath CM, Ronai Z. Cooperation between STAT3 and c-jun suppresses Fas transcription. Molecular Cell. 7: 517-28. PMID 11463377 DOI: 10.1016/S1097-2765(01)00199-X  0.349
2001 Parisien JP, Lau JF, Rodriguez JJ, Sullivan BM, Moscona A, Parks GD, Lamb RA, Horvath CM. The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. Virology. 283: 230-9. PMID 11336548 DOI: 10.1006/Viro.2001.0856  0.854
2001 Ehret GB, Reichenbach P, Schindler U, Horvath CM, Fritz S, Nabholz M, Bucher P. DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites. The Journal of Biological Chemistry. 276: 6675-88. PMID 11053426 DOI: 10.1074/Jbc.M001748200  0.421
2000 Horvath CM. STAT proteins and transcriptional responses to extracellular signals Trends in Biochemical Sciences. 25: 496-502. PMID 11050435 DOI: 10.1016/S0968-0004(00)01624-8  0.516
2000 Talon J, Horvath CM, Polley R, Basler CF, Muster T, Palese P, García-Sastre A. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. Journal of Virology. 74: 7989-96. PMID 10933707 DOI: 10.1128/Jvi.74.17.7989-7996.2000  0.574
2000 Lau JF, Parisien JP, Horvath CM. Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors. Proceedings of the National Academy of Sciences of the United States of America. 97: 7278-83. PMID 10860992 DOI: 10.1073/Pnas.97.13.7278  0.794
2000 Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM. Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 5208-13. PMID 10792030 DOI: 10.1073/Pnas.080469697  0.554
2000 Zong CS, Chan J, Levy DE, Horvath C, Sadowski HB, Wang LH. Mechanism of STAT3 activation by insulin-like growth factor I receptor Journal of Biological Chemistry. 275: 15099-15105. PMID 10747872 DOI: 10.1074/Jbc.M000089200  0.459
2000 Ram PT, Horvath CM, Iyengar R. Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein. Science (New York, N.Y.). 287: 142-4. PMID 10615050 DOI: 10.1126/Science.287.5450.142  0.474
1999 Zhang X, Wrzeszczynska MH, Horvath CM, Darnell JE. Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation. Molecular and Cellular Biology. 19: 7138-46. PMID 10490649 DOI: 10.1128/Mcb.19.10.7138  0.449
1998 Bromberg JF, Horvath CM, Besser D, Lathem WW, Darnell JE. Stat3 activation is required for cellular transformation by v-src. Molecular and Cellular Biology. 18: 2553-8. PMID 9566875 DOI: 10.1128/Mcb.18.5.2553  0.408
1997 Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR. Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases Science. 278: 1630-1632. PMID 9374464 DOI: 10.1126/Science.278.5343.1630  0.441
1997 Ceresa BP, Horvath CM, Pessin JE. Signal transducer and activator of transcription-3 serine phosphorylation by insulin is mediated by a Ras/Raf/MEK-dependent pathway. Endocrinology. 138: 4131-7. PMID 9322921 DOI: 10.1210/Endo.138.10.5266  0.346
1997 Horvath CM, Darnell JE. The state of the STATs: recent developments in the study of signal transduction to the nucleus. Current Opinion in Cell Biology. 9: 233-9. PMID 9069254 DOI: 10.1016/S0955-0674(97)80067-1  0.559
1996 Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM, Darnell JE. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proceedings of the National Academy of Sciences of the United States of America. 93: 15092-6. PMID 8986769 DOI: 10.1073/Pnas.93.26.15092  0.547
1996 Horvath CM, Stark GR, Kerr IM, Darnell JE. Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex. Molecular and Cellular Biology. 16: 6957-64. PMID 8943351 DOI: 10.1128/Mcb.16.12.6957  0.541
1996 Vaisse C, Halaas JL, Horvath CM, Darnell JE, Stoffel M, Friedman JM. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nature Genetics. 14: 95-7. PMID 8782827 DOI: 10.1038/Ng0996-95  0.435
1996 Bromberg JF, Horvath CM, Wen Z, Schreiber RD, Darnell JE. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proceedings of the National Academy of Sciences of the United States of America. 93: 7673-8. PMID 8755534 DOI: 10.1073/Pnas.93.15.7673  0.499
1996 Horvath CM, Darnell JE. The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein. Journal of Virology. 70: 647-50. PMID 8523587 DOI: 10.1128/Jvi.70.1.647-650.1996  0.631
1995 Horvath CM, Wen Z, Darnell JE. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes & Development. 9: 984-94. PMID 7774815 DOI: 10.1101/Gad.9.8.984  0.42
1994 Improta T, Schindler C, Horvath CM, Kerr IM, Stark GR, Darnell JE. Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 4776-80. PMID 8197134 DOI: 10.1073/Pnas.91.11.4776  0.574
1994 Shuai K, Horvath CM, Huang LH, Qureshi SA, Cowburn D, Darnell JE. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell. 76: 821-8. PMID 7510216 DOI: 10.1016/0092-8674(94)90357-3  0.546
1992 Horvath CM, Paterson RG, Shaughnessy MA, Wood R, Lamb RA. Biological activity of paramyxovirus fusion proteins: factors influencing formation of syncytia. Journal of Virology. 66: 4564-9. PMID 1602561 DOI: 10.1128/Jvi.66.7.4564-4569.1992  0.437
1992 Horvath CM, Lamb RA. Studies on the fusion peptide of a paramyxovirus fusion glycoprotein: roles of conserved residues in cell fusion. Journal of Virology. 66: 2443-55. PMID 1548771 DOI: 10.1128/Jvi.66.4.2443-2455.1992  0.387
1991 Lamb RA, Horvath CM. Diversity of coding strategies in influenza viruses. Trends in Genetics : Tig. 7: 261-6. PMID 1771674 DOI: 10.1016/0168-9525(91)90326-L  0.306
1990 Horvath CM, Williams MA, Lamb RA. Eukaryotic coupled translation of tandem cistrons: identification of the influenza B virus BM2 polypeptide. The Embo Journal. 9: 2639-47. PMID 2114979 DOI: 10.1002/J.1460-2075.1990.Tb07446.X  0.488
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