| Year |
Citation |
Score |
| 2019 |
Ma X, Lu JY, Moraru A, Teleman AA, Fang J, Qiu Y, Liu P, Xu T. A novel regulator of ER Ca drives Hippo-mediated tumorigenesis. Oncogene. PMID 31649333 DOI: 10.1038/S41388-019-1076-Z |
0.771 |
|
| 2019 |
Mishra-Gorur K, Li D, Ma X, Yarman Y, Xue L, Xu T. Spz/Toll-6 signal guides organotropic metastasis in . Disease Models & Mechanisms. PMID 31477571 DOI: 10.1242/Dmm.039727 |
0.789 |
|
| 2019 |
Chang H, Pan Y, Landrette S, Ding S, Yang D, Liu L, Tian L, Chai H, Li P, Li DM, Xu T. Efficient genome-wide first-generation phenotypic screening system in mice using the transposon. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451639 DOI: 10.1073/pnas.1906354116 |
0.318 |
|
| 2018 |
Dunn BS, Rush L, Lu JY, Xu T. Mutations in the tricellular junction protein M6 synergize with to induce apical cell delamination and invasion. Proceedings of the National Academy of Sciences of the United States of America. PMID 30061406 DOI: 10.1073/pnas.1807343115 |
0.376 |
|
| 2018 |
Ding Y, Cui J, Wang Q, Shen S, Xu T, Tang H, Han M, Wu X. The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice. Obesity (Silver Spring, Md.). PMID 29963761 DOI: 10.1002/Oby.22206 |
0.553 |
|
| 2018 |
Hu Z, Shen R, Campbell A, McMichael EL, Yu L, Ramaswamy B, London CA, Xu T, Carson WE. Targeting Tissue Factor for Immunotherapy of Triple-Negative Breast Cancer Using a Second-Generation ICON. Cancer Immunology Research. PMID 29622581 DOI: 10.1158/2326-6066.CIR-17-0343 |
0.33 |
|
| 2018 |
Ma X, Guo X, Richardson HE, Xu T, Xue L. POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29440430 DOI: 10.1073/Pnas.1715165115 |
0.788 |
|
| 2017 |
Ma X, Lu JY, Dong Y, Li D, Malagon JN, Xu T. PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-Dependent Tumor Growth and Invasion. Cell Reports. 19: 2657-2664. PMID 28658615 DOI: 10.1016/J.Celrep.2017.05.092 |
0.786 |
|
| 2017 |
Jin Y, Chen Y, Zhao S, Guan KL, Zhuang Y, Zhou W, Wu X, Xu T. DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28645898 DOI: 10.1073/Pnas.1612980114 |
0.467 |
|
| 2017 |
Zhu X, Xie S, Xu T, Wu X, Han M. Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders. Molecular Metabolism. 6: 494-502. PMID 28580280 DOI: 10.1016/J.Molmet.2017.03.003 |
0.555 |
|
| 2017 |
Li G, Ye Z, Shi C, Sun L, Han M, Zhuang Y, Xu T, Zhao S, Wu X. The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice. Scientific Reports. 7: 45401. PMID 28374742 DOI: 10.1038/Srep45401 |
0.597 |
|
| 2017 |
Gayle S, Landrette S, Beeharry N, Conrad C, Hernandez M, Beckett P, Ferguson SM, Xu T, Rothberg J, Lichenstein H. B-cell non-Hodgkin lymphoma: Selective vulnerability to PIKFYVE inhibition. Autophagy. 0. PMID 28350209 DOI: 10.1080/15548627.2017.1304871 |
0.302 |
|
| 2017 |
Chabu C, Li DM, Xu T. EGFR/ARF6 regulation of Hh signalling stimulates oncogenic Ras tumour overgrowth. Nature Communications. 8: 14688. PMID 28281543 DOI: 10.1038/ncomms14688 |
0.334 |
|
| 2017 |
Wu M, Pastor-Pareja JC, Xu T. Corrigendum: Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature. PMID 28199313 DOI: 10.1038/Nature21397 |
0.376 |
|
| 2017 |
Gayle S, Landrette S, Beeharry N, Conrad C, Hernandez M, Beckett P, Ferguson SM, Mandelkern T, Zheng M, Xu T, Rothberg J, Lichenstein H. Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma. Blood. PMID 28104689 DOI: 10.1182/Blood-2016-09-736892 |
0.336 |
|
| 2016 |
Cui J, Ding Y, Chen S, Zhu X, Wu Y, Zhang M, Zhao Y, Li TR, Sun LV, Zhao S, Zhuang Y, Jia W, Xue L, Han M, Xu T, et al. Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. The Journal of Clinical Investigation. PMID 27500489 DOI: 10.1172/Jci85676 |
0.713 |
|
| 2016 |
Ye Z, Sun L, Li R, Han M, Zhuang Y, Wu X, Xu T. Generation of a Mouse Full-length Balancer with Versatile Cassette-shuttling Selection Strategy. International Journal of Biological Sciences. 12: 911-6. PMID 27489495 DOI: 10.7150/Ijbs.15172 |
0.557 |
|
| 2016 |
Wang G, Li R, Yang Y, Cai L, Ding S, Xu T, Han M, Wu X. Disruption of the Golgi protein Otg1 gene causes defective hormone secretion and aberrant glucose homeostasis in mice. Cell & Bioscience. 6: 41. PMID 27293546 DOI: 10.1186/S13578-016-0108-4 |
0.606 |
|
| 2016 |
Li S, Mo K, Tian H, Chu C, Sun S, Tian L, Ding S, Li TR, Wu X, Liu F, Zhang Z, Xu T, Sun LV. Lmod2 piggyBac mutant mice exhibit dilated cardiomyopathy. Cell & Bioscience. 6: 38. PMID 27274810 DOI: 10.1186/S13578-016-0101-Y |
0.468 |
|
| 2016 |
Willsey HR, Zheng X, Carlos Pastor-Pareja J, Willsey AJ, Beachy PA, Xu T. Localized JNK signaling regulates organ size during development. Elife. 5. PMID 26974344 DOI: 10.7554/eLife.11491 |
0.347 |
|
| 2016 |
Willsey HR, Zheng X, Pastor-Pareja JC, Willsey AJ, Beachy PA, Xu T. Author response: Localized JNK signaling regulates organ size during development Elife. DOI: 10.7554/Elife.11491.021 |
0.304 |
|
| 2015 |
Xu T, Xie J, Zong X, Wang W, Ren H, Chen N. Pulse Wave Velocity: A Valuable Predictor for Cardio-Cerebrovascular Disease and Death in PD Patients. Blood Purification. 40: 203-208. PMID 26336918 DOI: 10.1159/000433516 |
0.335 |
|
| 2015 |
Xu T, Xie J, Wang W, Ren H, Chen N. Peritoneal-Pleural Leaks Demonstrated by CT Peritoneography. Case Reports in Nephrology and Dialysis. 5: 135-9. PMID 26266244 DOI: 10.1159/000430806 |
0.346 |
|
| 2015 |
Tian L, Ding S, You Y, Li TR, Liu Y, Wu X, Sun L, Xu T. Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy. Disease Models & Mechanisms. 8: 635-41. PMID 26035871 DOI: 10.1242/Dmm.019430 |
0.483 |
|
| 2015 |
Gayle S, Pan Y, Landrette S, Xu T. piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation. Stem Cell Reports. 4: 926-38. PMID 25866159 DOI: 10.1016/j.stemcr.2015.03.001 |
0.759 |
|
| 2015 |
Ye J, Shi H, Shen Y, Peng C, Liu Y, Li C, Deng K, Geng J, Xu T, Zhuang Y, Zheng B, Tao W. PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling. Journal of Immunology (Baltimore, Md. : 1950). 194: 1654-64. PMID 25609840 DOI: 10.4049/jimmunol.1401692 |
0.573 |
|
| 2014 |
Mishra-Gorur K, Ça?layan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümü? GT, Nishimura S, Han W, Tu S, Baran B, Gümü? H, Dilber C, Zaki MS, Hossni HA, ... ... Xu T, et al. Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors. Neuron. 84: 1226-39. PMID 25521378 DOI: 10.1016/J.Neuron.2014.12.014 |
0.359 |
|
| 2014 |
Chabu C, Xu T. Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth. Development (Cambridge, England). 141: 4729-39. PMID 25411211 DOI: 10.1242/dev.108092 |
0.362 |
|
| 2014 |
Ding S, Xu T, Wu X. Generation of genetically engineered mice by the piggyBac transposon system. Methods in Molecular Biology (Clifton, N.J.). 1194: 171-85. PMID 25064103 DOI: 10.1007/978-1-4939-1215-5_9 |
0.478 |
|
| 2014 |
Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, Zhang T, Ma F, Wang Q, Wang J, Deng K, ... ... Xu T, et al. Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. Nature Immunology. 15: 612-22. PMID 24859449 DOI: 10.1038/Ni.2898 |
0.411 |
|
| 2014 |
Du X, Dong Y, Shi H, Li J, Kong S, Shi D, Sun LV, Xu T, Deng K, Tao W. Mst1 and mst2 are essential regulators of trophoblast differentiation and placenta morphogenesis. Plos One. 9: e90701. PMID 24595170 DOI: 10.1371/journal.pone.0090701 |
0.597 |
|
| 2014 |
Ren J, Zhu H, Chi C, Mehrmohamadi M, Deng K, Wu X, Xu T. Beadex affects gastric emptying in Drosophila. Cell Research. 24: 636-9. PMID 24566770 DOI: 10.1038/Cr.2014.24 |
0.413 |
|
| 2014 |
Shi F, Ding S, Zhao S, Han M, Zhuang Y, Xu T, Wu X. A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Human Molecular Genetics. 23: 3792-800. PMID 24565867 DOI: 10.1093/Hmg/Ddu092 |
0.607 |
|
| 2014 |
Du X, Shi H, Li J, Dong Y, Liang J, Ye J, Kong S, Zhang S, Zhong T, Yuan Z, Xu T, Zhuang Y, Zheng B, Geng JG, Tao W. Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 192: 1525-35. PMID 24453252 DOI: 10.4049/jimmunol.1301060 |
0.572 |
|
| 2014 |
Choi J, Landrette SF, Wang T, Evans P, Bacchiocchi A, Bjornson R, Cheng E, Stiegler AL, Gathiaka S, Acevedo O, Boggon TJ, Krauthammer M, Halaban R, Xu T. Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell & Melanoma Research. 27: 253-62. PMID 24283590 DOI: 10.1111/Pcmr.12197 |
0.301 |
|
| 2014 |
Ma X, Li W, Yu H, Yang Y, Li M, Xue L, Xu T. Bendless modulates JNK-mediated cell death and migration in Drosophila Cell Death and Differentiation. 21: 407-415. PMID 24162658 DOI: 10.1038/Cdd.2013.154 |
0.792 |
|
| 2013 |
Xia M, Liu J, Wu X, Liu S, Li G, Han C, Song L, Li Z, Wang Q, Wang J, Xu T, Cao X. Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20. Immunity. 39: 470-81. PMID 24012418 DOI: 10.1016/J.Immuni.2013.08.016 |
0.42 |
|
| 2013 |
Ni TK, Landrette SF, Bjornson RD, Bosenberg MW, Xu T. Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma. Proceedings of the National Academy of Sciences of the United States of America. 110: E3640-9. PMID 24003131 DOI: 10.1073/Pnas.1314435110 |
0.797 |
|
| 2013 |
Pastor-Pareja JC, Xu T. Dissecting social cell biology and tumors using Drosophila genetics. Annual Review of Genetics. 47: 51-74. PMID 23988119 DOI: 10.1146/annurev-genet-110711-155414 |
0.375 |
|
| 2013 |
Kong S, Du X, Du X, Peng C, Wu Y, Li H, Jin X, Hou L, Deng K, Xu T, Tao W. Dlic1 deficiency impairs ciliogenesis of photoreceptors by destabilizing dynein. Cell Research. 23: 835-50. PMID 23628724 DOI: 10.1038/cr.2013.59 |
0.541 |
|
| 2013 |
Li R, Zhuang Y, Han M, Xu T, Wu X. piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice. Disease Models & Mechanisms. 6: 828-33. PMID 23519027 DOI: 10.1242/Dmm.010827 |
0.588 |
|
| 2012 |
Xu T, Rubin GM. The effort to make mosaic analysis a household tool. Development (Cambridge, England). 139: 4501-3. PMID 23172911 DOI: 10.1242/dev.085183 |
0.519 |
|
| 2012 |
Zhu Y, Liu S, Yin Q, Xu T, Wu X, Zhuang Y. Generation of Dhx9-deficient clones in T-cell development with a mitotic recombination technique. Genesis (New York, N.Y. : 2000). 50: 543-51. PMID 22988576 DOI: 10.1002/Dvg.22005 |
0.506 |
|
| 2012 |
Lei K, Zhu X, Xu R, Shao C, Xu T, Zhuang Y, Han M. Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response. Current Biology : Cb. 22: 1609-15. PMID 22863315 DOI: 10.1016/J.Cub.2012.06.043 |
0.478 |
|
| 2012 |
Peng C, Ye J, Yan S, Kong S, Shen Y, Li C, Li Q, Zheng Y, Deng K, Xu T, Tao W. Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. The Journal of Biological Chemistry. 287: 32861-73. PMID 22854957 DOI: 10.1074/Jbc.M112.384305 |
0.563 |
|
| 2012 |
Peng C, Yan S, Ye J, Shen L, Xu T, Tao W. Vps18 deficiency inhibits dendritogenesis in Purkinje cells by blocking the lysosomal degradation of Lysyl Oxidase. Biochemical and Biophysical Research Communications. 423: 715-20. PMID 22699122 DOI: 10.1016/j.bbrc.2012.06.021 |
0.56 |
|
| 2011 |
Cornett JC, Landrette SF, Xu T. Characterization of fluorescent eye markers for mammalian transgenic studies. Plos One. 6: e29486. PMID 22216292 DOI: 10.1371/journal.pone.0029486 |
0.601 |
|
| 2011 |
Landrette SF, Cornett JC, Ni TK, Bosenberg MW, Xu T. piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice. Plos One. 6: e26650. PMID 22039523 DOI: 10.1371/Journal.Pone.0026650 |
0.794 |
|
| 2011 |
Pastor-Pareja JC, Xu T. Shaping cells and organs in Drosophila by opposing roles of fat body-secreted Collagen IV and perlecan. Developmental Cell. 21: 245-56. PMID 21839919 DOI: 10.1016/j.devcel.2011.06.026 |
0.3 |
|
| 2011 |
Landrette SF, Xu T. Somatic genetics empowers the mouse for modeling and interrogating developmental and disease processes. Plos Genetics. 7: e1002110. PMID 21814514 DOI: 10.1371/journal.pgen.1002110 |
0.322 |
|
| 2011 |
Visser-Grieve S, Zhou Z, She YM, Huang H, Cyr TD, Xu T, Yang X. LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization. Cell Research. 21: 1513-6. PMID 21808298 DOI: 10.1038/cr.2011.122 |
0.315 |
|
| 2011 |
Yang X, Xu T. Molecular mechanism of size control in development and human diseases. Cell Research. 21: 715-29. PMID 21483452 DOI: 10.1038/cr.2011.63 |
0.379 |
|
| 2011 |
Ohsawa S, Sugimura K, Takino K, Xu T, Miyawaki A, Igaki T. Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila. Developmental Cell. 20: 315-28. PMID 21397843 DOI: 10.1016/J.Devcel.2011.02.007 |
0.447 |
|
| 2011 |
Yu J, Lei K, Zhou M, Craft CM, Xu G, Xu T, Zhuang Y, Xu R, Han M. KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Human Molecular Genetics. 20: 1061-73. PMID 21177258 DOI: 10.1093/Hmg/Ddq549 |
0.485 |
|
| 2011 |
Igaki T, Kanda H, Okano H, Xu T, Miura M. Eiger and wengen: the Drosophila orthologs of TNF/TNFR. Advances in Experimental Medicine and Biology. 691: 45-50. PMID 21153308 DOI: 10.1007/978-1-4419-6612-4_5 |
0.393 |
|
| 2011 |
Guo Z, Li H, Han M, Xu T, Wu X, Zhuang Y. Modeling Sjögren's syndrome with Id3 conditional knockout mice. Immunology Letters. 135: 34-42. PMID 20932862 DOI: 10.1016/J.Imlet.2010.09.009 |
0.596 |
|
| 2010 |
Zhang C, Tian L, Chi C, Wu X, Yang X, Han M, Xu T, Zhuang Y, Deng K. Adam10 is essential for early embryonic cardiovascular development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 2594-602. PMID 20803506 DOI: 10.1002/Dvdy.22391 |
0.625 |
|
| 2010 |
Yi J, Chen M, Wu X, Yang X, Xu T, Zhuang Y, Han M, Xu R. Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 2005-13. PMID 20549726 DOI: 10.1002/Dvdy.22343 |
0.629 |
|
| 2010 |
Chi C, Zhu H, Han M, Zhuang Y, Wu X, Xu T. Disruption of lysosome function promotes tumor growth and metastasis in Drosophila. The Journal of Biological Chemistry. 285: 21817-23. PMID 20418542 DOI: 10.1074/Jbc.M110.131714 |
0.631 |
|
| 2010 |
Wu M, Pastor-Pareja JC, Xu T. Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature. 463: 545-8. PMID 20072127 DOI: 10.1038/nature08702 |
0.509 |
|
| 2009 |
Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M. SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 64: 173-87. PMID 19874786 DOI: 10.1016/J.Neuron.2009.08.018 |
0.738 |
|
| 2009 |
Wu Y, Zhuang Y, Han M, Xu T, Deng K. Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye. Bmc Developmental Biology. 9: 53. PMID 19840402 DOI: 10.1186/1471-213X-9-53 |
0.493 |
|
| 2009 |
Dong Y, Du X, Ye J, Han M, Xu T, Zhuang Y, Tao W. A cell-intrinsic role for Mst1 in regulating thymocyte egress. Journal of Immunology (Baltimore, Md. : 1950). 183: 3865-72. PMID 19692642 DOI: 10.4049/Jimmunol.0900678 |
0.644 |
|
| 2009 |
Yu J, Ying M, Zhuang Y, Xu T, Han M, Wu X, Xu R. C-terminal deletion of the atrophin-1 protein results in growth retardation but not neurodegeneration in mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2471-8. PMID 19681162 DOI: 10.1002/Dvdy.22063 |
0.575 |
|
| 2009 |
Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M. SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 10207-12. PMID 19509342 DOI: 10.1073/Pnas.0812037106 |
0.719 |
|
| 2009 |
Igaki T, Pastor-Pareja JC, Aonuma H, Miura M, Xu T. Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila Developmental Cell. 16: 458-465. PMID 19289090 DOI: 10.1016/j.devcel.2009.01.002 |
0.428 |
|
| 2009 |
Liu J, Ghanim M, Xue L, Brown CD, Iossifov I, Angeletti C, Hua S, Nègre N, Ludwig M, Stricker T, Al-Ahmadie HA, Tretiakova M, Camp RL, Perera-Alberto M, Rimm DL, ... Xu T, et al. Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. Science (New York, N.Y.). 323: 1218-22. PMID 19164706 DOI: 10.1126/Science.1157669 |
0.671 |
|
| 2008 |
Pastor-Pareja JC, Wu M, Xu T. An innate immune response of blood cells to tumors and tissue damage in Drosophila. Disease Models & Mechanisms. 1: 144-54; discussion 1. PMID 19048077 DOI: 10.1242/Dmm.000950 |
0.463 |
|
| 2008 |
Nguyen D, Xu T. The expanding role of mouse genetics for understanding human biology and disease Disease Models & Mechanisms. 1: 56-66. PMID 19048054 DOI: 10.1242/Dmm.000232 |
0.349 |
|
| 2008 |
Xu R, Deng K, Zhu Y, Wu Y, Ren J, Wan M, Zhao S, Wu X, Han M, Zhuang Y, Xu T. A large-scale functional approach to uncover human genes and pathways in Drosophila. Cell Research. 18: 1114-27. PMID 18957936 DOI: 10.1038/Cr.2008.295 |
0.618 |
|
| 2008 |
Tian L, Wu X, Chi C, Han M, Xu T, Zhuang Y. ADAM10 is essential for proteolytic activation of Notch during thymocyte development. International Immunology. 20: 1181-7. PMID 18635581 DOI: 10.1093/Intimm/Dxn076 |
0.616 |
|
| 2008 |
Sun L, Wu X, Han M, Xu T, Zhuang Y. A mitotic recombination system for mouse chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. 105: 4237-41. PMID 18326030 DOI: 10.1073/Pnas.0800798105 |
0.57 |
|
| 2008 |
Sun LV, Jin K, Liu Y, Yang W, Xie X, Ye L, Wang L, Zhu L, Ding S, Su Y, Zhou J, Han M, Zhuang Y, Xu T, Wu X, et al. PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Research. 36: D729-34. PMID 17932058 DOI: 10.1093/Nar/Gkm790 |
0.552 |
|
| 2007 |
Xue L, Igaki T, Kuranaga E, Kanda H, Miura M, Xu T. Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila. Developmental Cell. 13: 446-54. PMID 17765686 DOI: 10.1016/j.devcel.2007.07.012 |
0.703 |
|
| 2007 |
Ding X, Xu R, Yu J, Xu T, Zhuang Y, Han M. SUN1 Is Required for Telomere Attachment to Nuclear Envelope and Gametogenesis in Mice Developmental Cell. 12: 863-872. PMID 17543860 DOI: 10.1016/J.Devcel.2007.03.018 |
0.464 |
|
| 2007 |
Srivastava A, Pastor-Pareja JC, Igaki T, Pagliarini R, Xu T. Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. Proceedings of the National Academy of Sciences of the United States of America. 104: 2721-6. PMID 17301221 DOI: 10.1073/Pnas.0611666104 |
0.747 |
|
| 2007 |
Zhang X, Xu R, Zhu B, Yang X, Ding X, Duan S, Xu T, Zhuang Y, Han M. Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation. Development (Cambridge, England). 134: 901-8. PMID 17267447 DOI: 10.1242/Dev.02783 |
0.715 |
|
| 2006 |
Wan M, Wu X, Guan KL, Han M, Zhuang Y, Xu T. Muscle atrophy in transgenic mice expressing a human TSC1 transgene. Febs Letters. 580: 5621-7. PMID 16996505 DOI: 10.1016/J.Febslet.2006.09.008 |
0.597 |
|
| 2006 |
Igaki T, Pagliarini RA, Xu T. Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila. Current Biology : Cb. 16: 1139-46. PMID 16753569 DOI: 10.1016/J.Cub.2006.04.042 |
0.737 |
|
| 2006 |
Ying M, Xu R, Wu X, Zhu H, Zhuang Y, Han M, Xu T. Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. The Journal of Biological Chemistry. 281: 12580-6. PMID 16407196 DOI: 10.1074/Jbc.M511677200 |
0.586 |
|
| 2006 |
Yu J, Starr DA, Wu X, Parkhurst SM, Zhuang Y, Xu T, Xu R, Han M. The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis. Developmental Biology. 289: 336-45. PMID 16337624 DOI: 10.1016/J.Ydbio.2005.10.027 |
0.581 |
|
| 2005 |
Ding S, Wu X, Li G, Han M, Zhuang Y, Xu T. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell. 122: 473-83. PMID 16096065 DOI: 10.1016/J.Cell.2005.07.013 |
0.601 |
|
| 2005 |
Zhu H, Wang G, Li G, Han M, Xu T, Zhuang Y, Wu X. Ubiquitous expression of mRFP1 in transgenic mice. Genesis (New York, N.Y. : 2000). 42: 86-90. PMID 15880439 DOI: 10.1002/Gene.20129 |
0.573 |
|
| 2005 |
Douglas RM, Farahani R, Morcillo P, Kanaan A, Xu T, Haddad GG. Hypoxia induces major effects on cell cycle kinetics and protein expression in Drosophila melanogaster embryos. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R511-21. PMID 15498965 DOI: 10.1152/ajpregu.00520.2004 |
0.335 |
|
| 2004 |
Busygina V, Suphapeetiporn K, Marek LR, Stowers RS, Xu T, Bale AE. Hypermutability in a Drosophila model for multiple endocrine neoplasia type 1 Human Molecular Genetics. 13: 2399-2408. PMID 15333582 DOI: 10.1093/Hmg/Ddh271 |
0.399 |
|
| 2004 |
Yang X, Yu K, Hao Y, Li DM, Stewart R, Insogna KL, Xu T. LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1. Nature Cell Biology. 6: 609-17. PMID 15220930 DOI: 10.1038/Ncb1140 |
0.584 |
|
| 2004 |
Pedraza LG, Stewart RA, Li DM, Xu T. Drosophila Src-family kinases function with Csk to regulate cell proliferation and apoptosis. Oncogene. 23: 4754-62. PMID 15107833 DOI: 10.1038/sj.onc.1207635 |
0.727 |
|
| 2003 |
Pagliarini RA, Xu T. A genetic screen in Drosophila for metastatic behavior. Science (New York, N.Y.). 302: 1227-31. PMID 14551319 DOI: 10.1126/science.1088474 |
0.71 |
|
| 2003 |
Stewart RA, Li DM, Huang H, Xu T. A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila. Oncogene. 22: 6436-44. PMID 14508523 DOI: 10.1038/sj.onc.1206820 |
0.646 |
|
| 2003 |
Chen Q, Behar KL, Xu T, Fan C, Haddad GG. Expression of Drosophila trehalose-phosphate synthase in HEK-293 cells increases hypoxia tolerance. The Journal of Biological Chemistry. 278: 49113-8. PMID 13129920 DOI: 10.1074/jbc.M308652200 |
0.343 |
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| 2003 |
Inoki K, Li Y, Xu T, Guan KL. Rheb GTpase is a direct target of TSC2 GAP activity and regulates mTOR signaling Genes and Development. 17: 1829-1834. PMID 12869586 DOI: 10.1101/gad.1110003 |
0.399 |
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| 2003 |
Pagliarini RA, Quiñones AT, Xu T. Analyzing the function of tumor suppressor genes using a Drosophila model. Methods in Molecular Biology (Clifton, N.J.). 223: 349-82. PMID 12777740 DOI: 10.1385/1-59259-329-1:349 |
0.703 |
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| 2003 |
Potter CJ, Pedraza LG, Huang H, Xu T. The tuberous sclerosis complex (TSC) pathway and mechanism of size control. Biochemical Society Transactions. 31: 584-6. PMID 12773160 DOI: 10.1042/ |
0.739 |
|
| 2002 |
Potter CJ, Pedraza LG, Xu T. Akt regulates growth by directly phosphorylating Tsc2. Nature Cell Biology. 4: 658-65. PMID 12172554 DOI: 10.1038/ncb840 |
0.725 |
|
| 2002 |
Xia H, Qi H, Li Y, Pei J, Barton J, Blackstad M, Xu T, Tao W. LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene. 21: 1233-41. PMID 11850843 DOI: 10.1038/sj.onc.1205174 |
0.615 |
|
| 2002 |
Zhang S, Xu L, Lee J, Xu T. Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes. Cell. 108: 45-56. PMID 11792320 DOI: 10.1016/S0092-8674(01)00630-4 |
0.474 |
|
| 2002 |
Chen Q, Ma E, Behar KL, Xu T, Haddad GG. Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. The Journal of Biological Chemistry. 277: 3274-9. PMID 11719513 DOI: 10.1074/jbc.M109479200 |
0.333 |
|
| 2001 |
Yang X, Li DM, Chen W, Xu T. Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G2/M arrest or apoptosis Oncogene. 20: 6516-6523. PMID 11641775 DOI: 10.1038/sj.onc.1204817 |
0.401 |
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| 2001 |
Potter CJ, Xu T. Mechanisms of size control. Current Opinion in Genetics & Development. 11: 279-86. PMID 11377964 DOI: 10.1016/S0959-437X(00)00191-X |
0.565 |
|
| 2001 |
Potter CJ, Huang H, Xu T. Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell. 105: 357-68. PMID 11348592 DOI: 10.1016/S0092-8674(01)00333-6 |
0.619 |
|
| 2001 |
Douglas RM, Xu T, Haddad GG. Cell cycle progression and cell division are sensitive to hypoxia in Drosophila melanogaster embryos American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 280: R1555-R1563. PMID 11294781 DOI: 10.1152/AJPREGU.2001.280.5.R1555 |
0.318 |
|
| 2000 |
Rooke JE, Theodosiou NA, Xu T. Clonal analysis in the examination of gene function in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 137: 15-22. PMID 10948521 DOI: 10.1385/1-59259-066-7:15 |
0.771 |
|
| 2000 |
Potter CJ, Turenchalk GS, Xu T. Drosophila in cancer research. An expanding role. Trends in Genetics : Tig. 16: 33-9. PMID 10637629 DOI: 10.1016/S0168-9525(99)01878-8 |
0.584 |
|
| 1999 |
Turenchalk GS, St John MA, Tao W, Xu T. The role of lats in cell cycle regulation and tumorigenesis. Biochimica Et Biophysica Acta. 1424: M9-M16. PMID 10528150 DOI: 10.1016/S0304-419X(99)00021-9 |
0.553 |
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| 1999 |
St John MA, Tao W, Fei X, Fukumoto R, Carcangiu ML, Brownstein DG, Parlow AF, McGrath J, Xu T. Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nature Genetics. 21: 182-6. PMID 9988269 DOI: 10.1038/5965 |
0.586 |
|
| 1999 |
Tao W, Zhang S, Turenchalk GS, Stewart RA, St John MA, Chen W, Xu T. Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nature Genetics. 21: 177-81. PMID 9988268 DOI: 10.1038/5960 |
0.729 |
|
| 1999 |
Qi H, Rand MD, Wu X, Sestan N, Wang W, Rakic P, Xu T, Artavanis-Tsakonas S. Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (New York, N.Y.). 283: 91-4. PMID 9872749 DOI: 10.1126/Science.283.5398.91 |
0.763 |
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| 1998 |
Rooke JE, Xu T. Positive and negative signals between interacting cells for establishing neural fate. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 209-14. PMID 9631648 DOI: 10.1002/(SICI)1521-1878(199803)20:3<209::AID-BIES4>3.0.CO;2-M |
0.628 |
|
| 1998 |
Yavari R, Adida C, Bray-Ward P, Brines M, Xu T. Human metalloprotease-disintegrin Kuzbanian regulates sympathoadrenal cell fate in development and neoplasia. Human Molecular Genetics. 7: 1161-7. PMID 9618175 DOI: 10.1093/Hmg/7.7.1161 |
0.716 |
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| 1998 |
Theodosiou NA, Xu T. Use of FLP/FRT system to study Drosophila development. Methods (San Diego, Calif.). 14: 355-65. PMID 9608507 DOI: 10.1006/meth.1998.0591 |
0.753 |
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| 1997 |
Haddad GG, Sun Ya, Wyman RJ, Xu T. Genetic basis of tolerance to O2 deprivation in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 94: 10809-12. PMID 9380715 DOI: 10.1073/pnas.94.20.10809 |
0.304 |
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| 1997 |
Hu G, Zhang S, Vidal M, La Baer J, Xu T, Fearon ER. Mammalian homologs of seven in absentia regulate DCC via the ubiquitin- proteasome pathway Genes and Development. 11: 2701-2714. PMID 9334332 DOI: 10.1101/Gad.11.20.2701 |
0.465 |
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| 1996 |
Rooke J, Pan D, Xu T, Rubin GM. KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis. Science (New York, N.Y.). 273: 1227-31. PMID 8703057 DOI: 10.1126/Science.273.5279.1227 |
0.747 |
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| 1994 |
Xu T, Harrison SD. Mosaic analysis using FLP recombinase. Methods in Cell Biology. 44: 655-81. PMID 7707974 DOI: 10.1016/S0091-679X(08)60937-1 |
0.568 |
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| 1990 |
Xu T, Rebay I, Fleming RJ, Scottgale TN, Artavanis-Tsakonas S. The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis. Genes & Development. 4: 464-75. PMID 2338245 DOI: 10.1101/Gad.4.3.464 |
0.78 |
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| 1985 |
Wharton KA, Johansen KM, Xu T, Artavanis-Tsakonas S. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell. 43: 567-81. PMID 3935325 DOI: 10.1016/0092-8674(85)90229-6 |
0.702 |
|
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