Brandon F. Keele, Ph.D. - Publications

Affiliations: 
2003 Brigham Young University, Provo, UT, United States 
Area:
Microbiology Biology, Molecular Biology, Pathology, Immunology

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kim J, Bose D, Araínga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, et al. TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo. Nature Communications. 15: 1348. PMID 38355731 DOI: 10.1038/s41467-024-45555-x  0.416
2024 Grunst MW, Gil HM, Grandea AG, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S, Fennessey CM, Friedrich TC, ... ... Keele BF, et al. Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge. Plos Pathogens. 20: e1011819. PMID 38252675 DOI: 10.1371/journal.ppat.1011819  0.356
2023 Solis-Leal A, Boby N, Mallick S, Cheng Y, Wu F, De La Torre G, Dufour J, Alvarez X, Shivanna V, Liu Y, Fennessey CM, Lifson JD, Li Q, Keele BF, Ling B. Lymphoid tissues contribute to plasma viral clonotypes early after antiretroviral therapy interruption in SIV-infected rhesus macaques. Science Translational Medicine. 15: eadi9867. PMID 38091409 DOI: 10.1126/scitranslmed.adi9867  0.408
2023 Docken SS, McCormick K, Pampena MB, Samer S, Lindemuth E, Pinkevych M, Viox EG, Wu Y, Schlub TE, Cromer D, Keele BF, Paiardini M, Betts MR, Bar KJ, Davenport MP. Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency. Plos Pathogens. 19: e1011755. PMID 38032851 DOI: 10.1371/journal.ppat.1011755  0.447
2023 Kim J, Bose D, Araínga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, et al. TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs . Biorxiv : the Preprint Server For Biology. PMID 38014094 DOI: 10.1101/2023.09.05.556422  0.418
2023 Pinkevych M, Docken SS, Okoye AA, Fennessey CM, Del Prete GQ, Pino M, Harper JL, Betts MR, Paiardini M, Keele BF, Davenport MP. Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication. Plos Pathogens. 19: e1011660. PMID 37801446 DOI: 10.1371/journal.ppat.1011660  0.465
2023 Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection. Plos Pathogens. 19: e1011676. PMID 37747933 DOI: 10.1371/journal.ppat.1011676  0.571
2023 Smedley J, Turkbey B, Bernardo ML, Del Prete GQ, Estes JD, Griffiths GL, Kobayashi H, Choyke PL, Lifson JD, Keele BF. Correction: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission. Plos One. 18: e0288566. PMID 37418480 DOI: 10.1371/journal.pone.0288566  0.563
2023 Bauer A, Lindemuth E, Marino FE, Krause R, Joy J, Docken SS, Mallick S, McCormick K, Holt C, Georgiev I, Felber B, Keele BF, Veazey R, Davenport MP, Li H, et al. Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques. Plos Pathogens. 19: e1011059. PMID 37399208 DOI: 10.1371/journal.ppat.1011059  0.462
2023 Solis-Leal A, Boby N, Mallick S, Cheng Y, Wu F, De La Torre G, Dufour J, Alvarez X, Shivanna V, Liu Y, Fennessey CM, Lifson JD, Li Q, Keele BF, Ling B. Lymphoid tissues contribute to viral clonotypes present in plasma at early post-ATI in SIV-infected rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 37398418 DOI: 10.1101/2023.05.30.542512  0.432
2023 Lisco A, Lange C, Manion M, Kuriakose S, Dewar R, Gorelick RJ, Huik K, Yu Q, Hammoud DA, Smith BR, Muranski P, Rehm C, Sherman BT, Sykes C, Lindo N, ... ... Keele BF, et al. Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV. Nature Medicine. PMID 37322122 DOI: 10.1038/s41591-023-02387-4  0.435
2023 Sanders-Beer BE, Archin NM, Brumme ZL, Busch M, Deleage C, O'Doherty U, Hughes SH, Jerome K, Jones RB, Karn J, Kearney MF, Keele B, Kulpa D, Laird G, Li JZ, et al. Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary. Aids Research and Human Retroviruses. PMID 37126090 DOI: 10.1089/AID.2022.0188  0.406
2023 Bochart RM, Busman-Sahay K, Bondoc S, Morrow DW, Ortiz AM, Fennessey CM, Fischer MB, Shiel O, Swanson T, Shriver-Munsch CM, Crank HB, Armantrout KM, Barber-Axthelm AM, Langner C, Moats CR, ... ... Keele BF, et al. Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 19: e1011343. PMID 37075022 DOI: 10.1371/journal.ppat.1011343  0.469
2023 Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques. Biorxiv : the Preprint Server For Biology. PMID 36909458 DOI: 10.1101/2023.03.01.530655  0.563
2023 Statzu M, Jin W, Fray EJ, Wong AKH, Kumar MR, Ferrer E, Docken SS, Pinkevych M, McBrien JB, Fennessey CM, Keele BF, Liang S, Harper JL, Mutascio S, Franchitti L, et al. CD8 lymphocytes do not impact SIV reservoir establishment under ART. Nature Microbiology. PMID 36690860 DOI: 10.1038/s41564-022-01311-9  0.519
2022 Woolley G, Mosher M, Kroll K, Jones R, Hueber B, Sugawara S, Manickam C, Terry K, Varner V, Lifton M, Ram D, Fennessey CM, Keele BF, Reeves RK. Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events. Journal of Virology. e0151922. PMID 36511699 DOI: 10.1128/jvi.01519-22  0.45
2022 Gorman J, Wang C, Mason RD, Nazzari AF, Welles HC, Zhou T, Bess JW, Bylund T, Lee M, Tsybovsky Y, Verardi R, Wang S, Yang Y, Zhang B, Rawi R, ... Keele BF, et al. Cryo-EM structures of prefusion SIV envelope trimer. Nature Structural & Molecular Biology. PMID 36344847 DOI: 10.1038/s41594-022-00852-1  0.321
2022 Rawson JMO, Nikolaitchik OA, Shakya S, Keele BF, Pathak VK, Hu WS. Transcription Start Site Heterogeneity and Preferential Packaging of Specific Full-Length RNA Species Are Conserved Features of Primate Lentiviruses. Microbiology Spectrum. e0105322. PMID 35736240 DOI: 10.1128/spectrum.01053-22  0.412
2022 Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, ... ... Keele BF, et al. A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection. Plos Pathogens. 18: e1010507. PMID 35714165 DOI: 10.1371/journal.ppat.1010507  0.338
2022 Pegu A, Xu L, DeMouth ME, Fabozzi G, March K, Almasri CG, Cully MD, Wang K, Yang ES, Dias J, Fennessey CM, Hataye J, Wei RR, Rao E, Casazza JP, ... ... Keele BF, et al. Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys. Cell Reports. 38: 110199. PMID 34986348 DOI: 10.1016/j.celrep.2021.110199  0.504
2021 Moriarty RV, Golfinos AE, Gellerup DD, Schweigert H, Mathiaparanam J, Balgeman AJ, Weiler AM, Friedrich TC, Keele BF, Davenport MP, Venturi V, O'Connor SL. The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth. Plos One. 16: e0260010. PMID 34855793 DOI: 10.1371/journal.pone.0260010  0.464
2021 Frank I, Cigoli M, Arif MS, Fahlberg MD, Maldonado S, Calenda G, Pegu A, Yang ES, Rawi R, Chuang GY, Geng H, Liu C, Zhou T, Kwong PD, Arthos J, ... ... Keele BF, et al. Blocking αβ integrin delays viral rebound in SHIV-infected macaques treated with anti-HIV broadly neutralizing antibodies. Science Translational Medicine. 13. PMID 34408080 DOI: 10.1126/scitranslmed.abf7201  0.412
2021 Immonen TT, Fennessey CM, Lipkey L, Thorpe A, Del Prete GQ, Lifson JD, Davenport MP, Keele BF. Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir. Plos Pathogens. 17: e1009686. PMID 34143853 DOI: 10.1371/journal.ppat.1009686  0.432
2021 Bochart RM, Busman-Sahay K, Bondoc S, Morrow DW, Ortiz AM, Fennessey CM, Fischer MB, Shiel O, Swanson T, Shriver-Munsch CM, Crank HB, Armantrout KM, Barber-Axthelm AM, Langner C, Moats CR, ... ... Keele BF, et al. Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 17: e1009565. PMID 33970966 DOI: 10.1371/journal.ppat.1009565  0.58
2021 Kleinman A, Sivanandham R, Sette P, Brocca-Cofano E, McAndrews C, Keele B, Pandrea I, Apetrei C. Lack of Specific Regulatory T-Cell Depletion and Cytoreduction Associated with Extensive Toxicity after Administration of Low and High Doses of Cyclophosphamide. Aids Research and Human Retroviruses. PMID 33957772 DOI: 10.1089/AID.2021.0036  0.398
2021 Boltz VF, Ceriani C, Rausch JW, Shao W, Bale MJ, Keele BF, Hoh R, Milush JM, Deeks SG, Maldarelli F, Kearney MF, Coffin JM. CpG Methylation Profiles of HIV-1 Pro-Viral DNA in Individuals on ART. Viruses. 13. PMID 33946976 DOI: 10.3390/v13050799  0.384
2021 Li H, Wang S, Lee FH, Roark RS, Murphy AI, Smith J, Zhao C, Rando J, Chohan N, Ding Y, Kim E, Lindemuth E, Bar KJ, Pandrea I, Apetrei C, ... Keele BF, et al. New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure. Journal of Virology. PMID 33658341 DOI: 10.1128/JVI.00071-21  0.575
2021 Okoye AA, Duell DD, Fukazawa Y, Varco-Merth B, Marenco A, Behrens H, Chaunzwa TM, Selseth AN, Gilbride RM, Shao J, Edlefsen PT, Geleziunas R, Pinkevych M, Davenport MP, Busman-Sahay K, ... ... Keele BF, et al. CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification. The Journal of Clinical Investigation. PMID 33630764 DOI: 10.1172/JCI141677  0.624
2021 Swanstrom AE, Immonen TT, Oswald K, Pyle C, Thomas JA, Bosche WJ, Silipino L, Hull M, Newman L, Coalter V, Wiles A, Wiles R, Kiser J, Morcock DR, Shoemaker R, ... ... Keele BF, et al. Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy. The Journal of Clinical Investigation. PMID 33465055 DOI: 10.1172/JCI142421  0.682
2020 Wei Q, Hargett AA, Knoppova B, Duverger A, Rawi R, Shen CH, Farney SK, Hall S, Brown R, Keele BF, Heath SL, Saag MS, Kutsch O, Chuang GY, Kwong PD, et al. Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies. Iscience. 23: 101711. PMID 33205023 DOI: 10.1016/j.isci.2020.101711  0.349
2020 Liu PT, Keele BF, Abbink P, Mercado NB, Liu J, Bondzie EA, Chandrashekar A, Borducchi EN, Hesselgesser J, Mish M, Chin G, Bekerman E, Geleziunas R, Barouch DH. Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation. Nature Communications. 11: 5412. PMID 33110078 DOI: 10.1038/s41467-020-19254-2  0.464
2020 Halvas EK, Joseph KW, Brandt LD, Guo S, Sobolewski MD, Jacobs JL, Tumiotto C, Bui JK, Cyktor JC, Keele BF, Morse GD, Bale MJ, Shao W, Kearney MF, Coffin JM, et al. HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus. The Journal of Clinical Investigation. PMID 33016926 DOI: 10.1172/JCI138099  0.435
2020 Wu Y, Pinkevych M, Xu Z, Keele BF, Davenport MP, Cromer D. Impact of fluctuation in frequency of human immunodeficiency virus/simian immunodeficiency virus reactivation during antiretroviral therapy interruption. Proceedings. Biological Sciences. 287: 20200354. PMID 32811309 DOI: 10.1098/rspb.2020.0354  0.524
2020 Rust BJ, Kean LS, Colonna L, Brandenstein K, Poole NH, Obenza W, Enstrom MR, Maldini CR, Ellis GI, Fennessey CM, Huang ML, Keele BF, Jerome K, Riley JL, Kiem HP, et al. Robust Expansion of HIV CAR T Cells Following Antigen Boosting in ART-Suppressed Nonhuman Primates. Blood. PMID 32614969 DOI: 10.1182/Blood.2020006372  0.502
2020 Raehtz KD, Barrenäs F, Xu C, Busman-Sahay K, Valentine A, Law L, Ma D, Policicchio BB, Wijewardana V, Brocca-Cofano E, Trichel A, Gale M, Keele BF, Estes JD, Apetrei C, et al. African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. Plos Pathogens. 16: e1008333. PMID 32119719 DOI: 10.1371/Journal.Ppat.1008333  0.664
2020 Nixon CC, Mavigner M, Sampey GC, Brooks AD, Spagnuolo RA, Irlbeck DM, Mattingly C, Ho PT, Schoof N, Cammon CG, Tharp GK, Kanke M, Wang Z, Cleary RA, Upadhyay AA, ... ... Keele BF, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. PMID 31969707 DOI: 10.1038/S41586-020-1951-3  0.527
2020 Melody K, Roy CN, Kline C, Cottrell ML, Evans D, Shutt K, Pennings PS, Keele BF, Bility M, Kashuba ADM, Ambrose Z. Long-acting rilpivirine (RPV LA) pre-exposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 nor select for high frequency drug resistance in humanized mice. Journal of Virology. PMID 31969438 DOI: 10.1128/Jvi.01912-19  0.432
2019 Immonen TT, Camus C, Reid C, Fennessey CM, Del Prete GQ, Davenport MP, Lifson JD, Keele BF. Genetically barcoded SIV reveals the emergence of escape mutations in multiple viral lineages during immune escape. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843933 DOI: 10.1073/pnas.1914967117  0.325
2019 Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, ... ... Keele BF, et al. Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31776247 DOI: 10.1073/Pnas.1910334116  0.401
2019 Hataye JM, Casazza JP, Best K, Liang CJ, Immonen TT, Ambrozak DR, Darko S, Henry AR, Laboune F, Maldarelli F, Douek DC, Hengartner NW, Yamamoto T, Keele BF, Perelson AS, et al. Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread. Cell Host & Microbe. PMID 31761718 DOI: 10.1016/j.chom.2019.10.006  0.559
2019 Pinkevych M, Fennessey CM, Cromer D, Reid C, Trubey CM, Lifson JD, Keele BF, Davenport MP. Predictors of SIV recrudescence following antiretroviral treatment interruption. Elife. 8. PMID 31650954 DOI: 10.7554/eLife.49022  0.417
2019 Musick A, Spindler J, Boritz E, Pérez L, Crespo-Vélez D, Patro SC, Sobolewski MD, Bale MJ, Reid C, Keele BF, Capoferri A, Shao W, Wiegand A, Simonetti FR, Mellors JW, et al. HIV Infected T Cells Can Proliferate Without Inducing Expression of the Integrated Provirus. Frontiers in Microbiology. 10: 2204. PMID 31632364 DOI: 10.3389/Fmicb.2019.02204  0.546
2019 Long S, Fennessey CM, Newman L, Reid C, O'Brien SP, Li Y, Del Prete GQ, Lifson JD, Gorelick RJ, Keele BF. Evaluating the intactness of persistent viral genomes in SIV-infected rhesus macaques initiating antiretroviral therapy within one year of infection. Journal of Virology. PMID 31597776 DOI: 10.1128/JVI.01308-19  0.416
2019 Khanal S, Fennessey CM, O'Brien SP, Thorpe A, Reid C, Immonen TT, Smith R, Bess JW, Swanstrom AE, Del Prete GQ, Davenport MP, Okoye AA, Picker LJ, Lifson JD, Keele BF. validation of the viral barcoding of SIVmac239 and the development of new barcoded SIV and subtype B and C SHIVs. Journal of Virology. PMID 31597757 DOI: 10.1128/JVI.01420-19  0.44
2019 Redd AD, Doria-Rose NA, Weiner JA, Nason M, Seivers M, Schmidt SD, Laeyendecker O, Martens C, Bruno D, Keele BF, Raju N, Georgiev IS, Lamers SL, Astemborski J, Kirk GD, et al. Longitudinal antibody responses in people who inject drugs infected with similar HIV strains. The Journal of Infectious Diseases. PMID 31581292 DOI: 10.1093/Infdis/Jiz503  0.424
2019 Abbink P, Mercado NB, Nkolola JP, Peterson RL, Tuyishime H, McMahan K, Moseley ET, Borducchi EN, Chandrashekar A, Bondzie EA, Agarwal A, Belli AJ, Reimann KA, Keele BF, Geleziunas R, et al. Lack of therapeutic efficacy of an antibody to αβ in SIVmac251-infected rhesus macaques. Science (New York, N.Y.). 365: 1029-1033. PMID 31488689 DOI: 10.1126/science.aaw8562  0.493
2019 Di Mascio M, Lifson JD, Srinivasula S, Kim I, DeGrange P, Keele BF, Belli AJ, Reimann KA, Wang Y, Proschan M, Lane HC, Fauci AS. Evaluation of an antibody to αβ in the control of SIVmac239- infection. Science (New York, N.Y.). 365: 1025-1029. PMID 31488688 DOI: 10.1126/Science.Aav6695  0.398
2019 Yu WH, Su D, Torabi J, Fennessey CM, Shiakolas A, Lynch R, Chun TW, Doria-Rose N, Alter G, Seaman MS, Keele BF, Lauffenburger DA, Julg B. Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir. Jci Insight. 4. PMID 31484826 DOI: 10.1172/Jci.Insight.130153  0.456
2019 Deleage C, Immonen TT, Fennessey CM, Reynaldi A, Reid C, Newman L, Lipkey L, Schlub TE, Camus C, O'Brien S, Smedley J, Conway JM, Del Prete GQ, Davenport MP, Lifson JD, ... ... Keele BF, et al. Defining early SIV replication and dissemination dynamics following vaginal transmission. Science Advances. 5: eaav7116. PMID 31149634 DOI: 10.1126/Sciadv.Aav7116  0.648
2019 Schmidt F, Keele BF, Del Prete GQ, Voronin D, Fennessey CM, Soll S, Kane M, Raymond A, Gifford RJ, KewalRamani V, Lifson JD, Bieniasz PD, Hatziioannou T. Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host. Proceedings of the National Academy of Sciences of the United States of America. PMID 31048506 DOI: 10.1073/Pnas.1818059116  0.473
2019 Fennessey CM, Camus C, Immonen TT, Reid C, Maldarelli F, Lifson JD, Keele BF. Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo. Retrovirology. 16: 11. PMID 30947720 DOI: 10.1186/s12977-019-0473-2  0.306
2019 O'Brien SP, Swanstrom AE, Pegu A, Ko SY, Immonen TT, Del Prete GQ, Fennessey CM, Gorman J, Foulds KE, Schmidt SD, Doria-Rose N, Williamson C, Hatziioannou T, Bieniasz PD, Li H, ... ... Keele BF, et al. Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes. Plos Pathogens. 15: e1007632. PMID 30943274 DOI: 10.1371/journal.ppat.1007632  0.484
2019 Martinez-Navio JM, Fuchs SP, Pantry SN, Lauer WA, Duggan NN, Keele BF, Rakasz EG, Gao G, Lifson JD, Desrosiers RC. Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can Drive Long-Term Virologic Suppression. Immunity. PMID 30850342 DOI: 10.1016/J.Immuni.2019.02.005  0.389
2019 Patro SC, Wu X, Guo S, Bale MJ, Wiegand A, Spindler J, Fennessey CM, Halvas EK, Keele BF, Hughes SH, Mellors JW, Coffin JM, Rausch JW, Kearney MF. A9 A method to obtain full-length HIV proviral sequences and their sites of integration Virus Evolution. 5. DOI: 10.1093/Ve/Vez002.008  0.366
2018 Van Rompay KK, Hassounah S, Keele BF, Lifson JD, Ardeshir A, Watanabe J, Pham HT, Chertova E, Sowder R, Balzarini J, Mesplède T, Wainberg MA. Dolutegravir monotherapy of simian immunodeficiency virus-infected macaques selects for several patterns of resistance mutations with variable virological outcomes. Journal of Virology. PMID 30381490 DOI: 10.1128/Jvi.01189-18  0.432
2018 Rawson JMO, Nikolaitchik OA, Keele BF, Pathak VK, Hu WS. Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity. Nucleic Acids Research. PMID 30307534 DOI: 10.1093/nar/gky910  0.405
2018 Struwe WB, Chertova E, Allen JD, Seabright GE, Watanabe Y, Harvey DJ, Medina-Ramirez M, Roser JD, Smith R, Westcott D, Keele BF, Bess JW, Sanders RW, Lifson JD, Moore JP, et al. Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen. Cell Reports. 24: 1958-1966.e5. PMID 30134158 DOI: 10.1016/j.celrep.2018.07.080  0.327
2018 Brocca-Cofano E, Xu C, Wetzel KS, Cottrell ML, Policicchio BB, Raehtz KD, Ma D, Dunsmore T, Haret-Richter GS, Musaitif K, Keele BF, Kashuba AD, Collman RG, Pandrea I, Apetrei C. Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques. Journal of Virology. PMID 29925666 DOI: 10.1128/Jvi.00576-18  0.474
2018 Hensley-McBain T, Berard AR, Manuzak JA, Miller CJ, Zevin AS, Polacino P, Gile J, Agricola B, Cameron M, Hu SL, Estes JD, Reeves RK, Smedley J, Keele BF, Burgener AD, et al. Intestinal damage precedes mucosal immune dysfunction in SIV infection. Mucosal Immunology. PMID 29907866 DOI: 10.1038/S41385-018-0032-5  0.596
2018 Swanstrom AE, Gorelick RJ, Wu G, Howell B, Vijayagopalan A, Shoemaker R, Oswald K, Datta SA, Keele B, Del Prete G, Chertova E, Bess J, Lifson J. Ultrasenstive Immunoassay for SIV p27CA. Aids Research and Human Retroviruses. PMID 29869527 DOI: 10.1089/AID.2018.0075  0.425
2018 Vaccari M, Fourati S, Gordon SN, Brown DR, Bissa M, Schifanella L, Silva de Castro I, Doster MN, Galli V, Omsland M, Fujikawa D, Gorini G, Liyanage NPM, Trinh HV, McKinnon KM, ... ... Keele BF, et al. HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 monocytes is associated with a decreased risk of SIV acquisition. Nature Medicine. PMID 29785023 DOI: 10.1038/S41591-018-0025-7  0.339
2018 Song H, Giorgi EE, Ganusov VV, Cai F, Athreya G, Yoon H, Carja O, Hora B, Hraber P, Romero-Severson E, Jiang C, Li X, Wang S, Li H, Salazar-Gonzalez JF, ... ... Keele BF, et al. Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. Nature Communications. 9: 1928. PMID 29765018 DOI: 10.1038/S41467-018-04217-5  0.512
2018 Houzet L, Pérez-Losada M, Matusali G, Deleage C, Dereuddre-Bosquet N, Satie AP, Aubry F, Becker E, Jégou B, Le Grand R, Keele BF, Crandall KA, Dejucq-Rainsford N. Seminal SIV in chronically-infected cynomolgus macaques is dominated by virus originating from multiple genital organs. Journal of Virology. PMID 29720516 DOI: 10.1128/Jvi.00133-18  0.492
2017 Pinkevych M, Fennessey CM, Cromer D, Tolstrup M, Søgaard OS, Rasmussen TA, Keele BF, Davenport MP. Estimating initial viral levels during HIV/SIV reactivation from latency. Journal of Virology. PMID 29118123 DOI: 10.1128/JVI.01667-17  0.543
2017 Del Prete GQ, Keele BF, Fode J, Thumar K, Swanstrom AE, Rodriguez A, Raymond A, Estes JD, LaBranche CC, Montefiori DC, KewalRamani VN, Lifson JD, Bieniasz PD, Hatziioannou T. A single gp120 residue can affect HIV-1 tropism in macaques. Plos Pathogens. 13: e1006572. PMID 28945790 DOI: 10.1371/Journal.Ppat.1006572  0.674
2017 Sauermann U, Radaelli A, Stolte-Leeb N, Raue K, Bissa M, Zanotto C, Krawczak M, Tenbusch M, Überla K, Keele BF, De Giuli Morghen C, Sopper S, Stahl-Hennig C. Vector order determines protection against pathogenic simian immunodeficiency virus infection in a triple component vaccine by balancing CD4(+) and CD8(+) T-cell responses. Journal of Virology. PMID 28904195 DOI: 10.1128/JVI.01120-17  0.38
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2012 Lee HY, Giorgi EE, Keele BF, Gaschen B, Athreya GS, Salazar-Gonzalez JF, Pham KT, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Hahn BH, Shaw GM, Korber BT, et al. Corrigendum to "Modeling sequence evolution in acute HIV-1 infection" [J. Theor. Biol. 261 (2009) 341-360] Journal of Theoretical Biology. 297: 187. DOI: 10.1016/J.Jtbi.2011.12.010  0.448
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2011 Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. Plos Pathogens. 7: e1002209. PMID 21980282 DOI: 10.1371/Journal.Ppat.1002209  0.408
2011 Fenizia C, Keele BF, Nichols D, Cornara S, Binello N, Vaccari M, Pegu P, Robert-Guroff M, Ma ZM, Miller CJ, Venzon D, Hirsch V, Franchini G. TRIM5α does not affect simian immunodeficiency virus SIV(mac251) replication in vaccinated or unvaccinated Indian rhesus macaques following intrarectal challenge exposure. Journal of Virology. 85: 12399-409. PMID 21917950 DOI: 10.1128/Jvi.05707-11  0.322
2011 Asmal M, Hellmann I, Liu W, Keele BF, Perelson AS, Bhattacharya T, Gnanakaran S, Daniels M, Haynes BF, Korber BT, Hahn BH, Shaw GM, Letvin NL. A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity. Plos One. 6: e23673. PMID 21876761 DOI: 10.1371/Journal.Pone.0023673  0.459
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2011 Ma ZM, Keele BF, Qureshi H, Stone M, Desilva V, Fritts L, Lifson JD, Miller CJ. SIVmac251 is inefficiently transmitted to rhesus macaques by penile inoculation with a single SIVenv variant found in ramp-up phase plasma. Aids Research and Human Retroviruses. 27: 1259-69. PMID 21732792 DOI: 10.1089/Aid.2011.0090  0.531
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2010 Rudicell RS, Holland Jones J, Wroblewski EE, Learn GH, Li Y, Robertson JD, Greengrass E, Grossmann F, Kamenya S, Pintea L, Mjungu DC, Lonsdorf EV, Mosser A, Lehman C, Collins DA, ... Keele BF, et al. Impact of simian immunodeficiency virus infection on chimpanzee population dynamics. Plos Pathogens. 6: e1001116. PMID 20886099 DOI: 10.1371/Journal.Ppat.1001116  0.339
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2010 Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of Virology. 84: 10406-12. PMID 20686016 DOI: 10.1128/Jvi.01155-10  0.502
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2010 Stone M, Keele BF, Ma ZM, Bailes E, Dutra J, Hahn BH, Shaw GM, Miller CJ. A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251. Journal of Virology. 84: 7083-95. PMID 20463069 DOI: 10.1128/Jvi.00481-10  0.477
2010 Bar KJ, Li H, Chamberland A, Tremblay C, Routy JP, Grayson T, Sun C, Wang S, Learn GH, Morgan CJ, Schumacher JE, Haynes BF, Keele BF, Hahn BH, Shaw GM. Wide variation in the multiplicity of HIV-1 infection among injection drug users. Journal of Virology. 84: 6241-7. PMID 20375173 DOI: 10.1128/Jvi.00077-10  0.496
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2010 Kraus MH, Parrish NF, Shaw KS, Decker JM, Keele BF, Salazar-Gonzalez JF, Grayson T, McPherson DT, Ping LH, Anderson JA, Swanstrom R, Williamson C, Shaw GM, Hahn BH. A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays. Virology. 397: 346-57. PMID 20003995 DOI: 10.1016/J.Virol.2009.11.019  0.398
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2009 Haaland RE, Hawkins PA, Salazar-Gonzalez J, Johnson A, Tichacek A, Karita E, Manigart O, Mulenga J, Keele BF, Shaw GM, Hahn BH, Allen SA, Derdeyn CA, Hunter E. Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1. Plos Pathogens. 5: e1000274. PMID 19165325 DOI: 10.1371/Journal.Ppat.1000274  0.463
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