Bruce A. Tucker, Ph.D. - Publications

Affiliations: 
2001 Regent University 
Area:
Clergy Religion, Management Business Administration, Religious Education, Biography

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Voigt AP, Whitmore SS, Mulfaul K, Chirco KR, Giacalone JC, Flamme-Wiese MJ, Stockman A, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype. Microvascular Research. 104031. PMID 32531351 DOI: 10.1016/J.Mvr.2020.104031  0.302
2020 Voigt AP, Binkley E, Flamme-Wiese MJ, Zeng S, DeLuca AP, Scheetz TE, Tucker BA, Mullins RF, Stone EM. Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations. Cells. 9. PMID 32069977 DOI: 10.3390/Cells9020438  0.464
2019 Voigt AP, Mulfaul K, Mullin NK, Flamme-Wiese MJ, Giacalone JC, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 31712411 DOI: 10.1073/Pnas.1914143116  0.462
2019 Han IC, Burnight E, Ulferts MJ, Worthington KS, Russell SR, Sohn EH, Mullins RF, Stone E, Tucker BA, Wiley LA. Helper-Dependent Adenovirus Transduces the Human and Rat Retina but Elicits an Inflammatory Reaction When Delivered Subretinally in Rats. Human Gene Therapy. PMID 31456426 DOI: 10.1089/Hum.2019.159  0.302
2019 Shrestha A, Allen BN, Wiley LA, Tucker BA, Worthington KS. Development of High-Resolution Three-Dimensional-Printed Extracellular Matrix Scaffolds and Their Compatibility with Pluripotent Stem Cells and Early Retinal Cells. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 31414943 DOI: 10.1089/jop.2018.0146  0.331
2019 Voigt AP, Whitmore SS, Flamme-Wiese MJ, Riker M, Wiley LA, Tucker BA, Stone EM, Mullins RF, Scheetz TE. Molecular characterization of foveal versus peripheral human retina by single-cell RNA sequencing. Experimental Eye Research. PMID 31075224 DOI: 10.1016/J.Exer.2019.05.001  0.384
2019 Thompson JR, Worthington KS, Green BJ, Mullin NK, Jiao C, Kaalberg EE, Wiley LA, Han IC, Russell SR, Sohn EH, Guymon CA, Mullins RF, Stone EM, Tucker BA. Two-photon Polymerized Poly(caprolactone) Retinal Cell Delivery Scaffolds and their Systemic and Retinal Biocompatibility. Acta Biomaterialia. PMID 31055121 DOI: 10.1016/J.Actbio.2019.04.057  0.314
2019 Sohn EH, Flamme-Wiese MJ, Whitmore SS, Workalemahu G, Marneros AG, Boese EA, Kwon YH, Wang K, Abramoff MD, Tucker BA, Stone EM, Mullins RF. Choriocapillaris Degeneration in Geographic Atrophy. The American Journal of Pathology. PMID 31051169 DOI: 10.1016/J.Ajpath.2019.04.005  0.314
2019 Scruggs BA, Jiao C, Cranston CM, Kaalberg E, Wang K, Russell SR, Wiley LA, Mullins RF, Stone EM, Tucker BA, Sohn EH. Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments. Stem Cells Translational Medicine. PMID 31004408 DOI: 10.1002/Sctm.18-0210  0.374
2019 Bohrer LR, Wiley LA, Burnight ER, Cooke JA, Giacalone JC, Anfinson KR, Andorf JL, Mullins RF, Stone EM, Tucker BA. Correction of NR2E3 Associated Enhanced S-cone Syndrome Patient-specific iPSCs using CRISPR-Cas9. Genes. 10. PMID 30959774 DOI: 10.3390/Genes10040278  0.445
2019 Zhang Q, Giacalone JC, Searby C, Stone EM, Tucker BA, Sheffield VC. Disruption of RPGR protein interaction network is the common feature of RPGR missense variations that cause XLRP. Proceedings of the National Academy of Sciences of the United States of America. PMID 30622176 DOI: 10.1073/Pnas.1817639116  0.406
2018 Burnight ER, Bohrer LR, Giacalone JC, Klaahsen DL, Daggett HT, East JS, Madumba RA, Worthington KS, Mullins RF, Stone EM, Tucker BA, Wiley LA. CRISPR-Cas9-Mediated Correction of the 1.02 kb Common Deletion in in Induced Pluripotent Stem Cells from Patients with Batten Disease. The Crispr Journal. 1: 75-87. PMID 31021193 DOI: 10.1089/crispr.2017.0015  0.437
2018 Burnight ER, Giacalone JC, Cooke JA, Thompson JR, Bohrer LR, Chirco KR, Drack AV, Fingert JH, Worthington KS, Wiley LA, Mullins RF, Stone EM, Tucker BA. CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration. Progress in Retinal and Eye Research. PMID 29578069 DOI: 10.1016/J.Preteyeres.2018.03.003  0.443
2017 Wiley LA, Burnight E, Kaalberg EE, Jiao C, Riker MJ, Halder JA, Luse MA, Han IC, Russell SR, Sohn EH, Stone E, Tucker BA, Mullins RF. ASSESSMENT OF AAV SEROTYPE TROPISM IN HUMAN RETINAL EXPLANTS. Human Gene Therapy. PMID 29160116 DOI: 10.1089/Hum.2017.179  0.365
2017 Chirco KR, Lewis CJ, Scheetz TE, Johnston RM, Tucker BA, Stone EM, Fingert JH, Mullins RF. Evaluation of sFLT1 protein levels in human eyes with the FLT1 rs9943922 polymorphism. Ophthalmic Genetics. 1-5. PMID 28949775 DOI: 10.1080/13816810.2017.1369550  0.588
2017 Wiley LA, Anfinson KR, Cranston CM, Kaalberg EE, Collins MM, Mullins RF, Stone EM, Tucker BA. Generation of Xeno-Free, cGMP-Compliant Patient-Specific iPSCs from Skin Biopsy. Current Protocols in Stem Cell Biology. 42: 4A.12.1-4A.12.14. PMID 28806854 DOI: 10.1002/Cpsc.30  0.362
2017 Burnight ER, Gupta M, Wiley LA, Anfinson KR, Tran A, Triboulet R, Hoffmann JM, Klaahsen DL, Andorf JL, Jiao C, Sohn EH, Adur MK, Ross JW, Mullins RF, Daley GQ, ... ... Tucker BA, et al. Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28619647 DOI: 10.1016/J.Ymthe.2017.05.015  0.463
2017 Stone EM, Andorf JL, Whitmore SS, DeLuca AP, Giacalone JC, Streb LM, Braun TA, Mullins RF, Scheetz TE, Sheffield VC, Tucker BA. Clinically Focused Molecular Investigation of 1000 Consecutive Families with Inherited Retinal Disease. Ophthalmology. PMID 28559085 DOI: 10.1016/J.Ophtha.2017.04.008  0.327
2017 Songstad AE, Worthington KS, Chirco KR, Giacalone JC, Whitmore SS, Anfinson KR, Ochoa D, Cranston CM, Riker MJ, Neiman M, Stone EM, Mullins RF, Tucker BA. Connective Tissue Growth Factor Promotes Efficient Generation of Human induced pluripotent stem cell-Derived Choroidal Endothelium. Stem Cells Translational Medicine. PMID 28474838 DOI: 10.1002/Sctm.16-0399  0.364
2017 Sharma TP, Wiley LA, Whitmore SS, Anfinson KR, Cranston CM, Oppedal DJ, Daggett HT, Mullins RF, Tucker BA, Stone EM. Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa. Stem Cell Research. 21: 58-70. PMID 28390992 DOI: 10.1016/J.Scr.2017.03.005  0.478
2017 Worthington KS, Wiley LA, Kaalberg EE, Collins MM, Mullins RF, Stone EM, Tucker BA. Two-photon polymerization for production of human iPSC-derived retinal cell grafts. Acta Biomaterialia. PMID 28351682 DOI: 10.1016/J.Actbio.2017.03.039  0.332
2016 Chirco KR, Sohn EH, Stone EM, Tucker BA, Mullins RF. Structural and molecular changes in the aging choroid: implications for age-related macular degeneration. Eye (London, England). PMID 27716746 DOI: 10.1038/Eye.2016.216  0.432
2016 Wiley LA, Burnight ER, DeLuca AP, Anfinson KR, Cranston CM, Kaalberg EE, Penticoff JA, Affatigato LM, Mullins RF, Stone EM, Tucker BA. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Scientific Reports. 6: 30742. PMID 27471043 DOI: 10.1038/Srep30742  0.428
2016 Wiley LA, Burnight E, Drack AV, Banach BB, Ochoa D, Cranston CM, Madumba RA, East JS, Mullins RF, Stone E, Tucker BA. Using patient-specific induced pluripotent stem cells and wild-type mice to develop a gene augmentation-based strategy to treat CLN3-associated retinal degeneration. Human Gene Therapy. PMID 27400765 DOI: 10.1089/hum.2016.049  0.425
2016 Chirco KR, Scott Whitmore S, Wang K, Potempa LA, Halder JA, Stone EM, Tucker BA, Mullins RF. Monomeric C-reactive protein and inflammation in Age-related Macular Degeneration The role of monomeric C-reactive protein in AMD. The Journal of Pathology. PMID 27376713 DOI: 10.1002/Path.4766  0.412
2016 Zhu W, Gramlich OW, Laboissonniere L, Jain A, Sheffield VC, Trimarchi JM, Tucker BA, Kuehn MH. Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274060 DOI: 10.1073/Pnas.1604153113  0.351
2016 Wiley LA, Kaalberg EE, Penticoff JA, Mullins RF, Stone EM, Tucker BA. Expression of the retina-specific flippase, ABCA4, in epidermal keratinocytes F1000research. 5: 193. DOI: 10.12688/F1000Research.8089.1  0.489
2015 Songstad AE, Wiley LA, Duong K, Kaalberg E, Flamme-Wiese MJ, Cranston CM, Riker MJ, Levasseur D, Stone EM, Mullins RF, Tucker BA. Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 56: 8258-67. PMID 26720480 DOI: 10.1167/Iovs.15-17073  0.349
2015 Giacalone JC, Wiley LA, Burnight ER, Songstad AE, Mullins RF, Stone EM, Tucker BA. Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. Stem Cells Translational Medicine. PMID 26683869 DOI: 10.5966/Sctm.2015-0206  0.386
2015 Zeng S, Whitmore SS, Sohn EH, Riker MJ, Wiley LA, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Molecular Response of Chorioretinal Endothelial Cells to Complement Injury: Implications for Macular Degeneration. The Journal of Pathology. PMID 26564985 DOI: 10.1002/Path.4669  0.317
2015 Small KW, DeLuca AP, Whitmore SS, Rosenberg T, Silva-Garcia R, Udar N, Puech B, Garcia CA, Rice TA, Fishman GA, Héon E, Folk JC, Streb LM, Haas CM, Wiley LA, ... ... Tucker BA, et al. North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13. Ophthalmology. PMID 26507665 DOI: 10.1016/J.Ophtha.2015.10.006  0.414
2015 DeLuca AP, Whitmore SS, Barnes J, Sharma TP, Westfall TA, Scott CA, Weed MC, Wiley JS, Wiley LA, Johnston RM, Schnieders MJ, Lentz SR, Tucker BA, Mullins RF, Scheetz TE, et al. Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. Human Molecular Genetics. PMID 26494905 DOI: 10.1093/Hmg/Ddv446  0.61
2015 Tucker BA, Cranston CM, Anfinson KA, Shrestha S, Streb LM, Leon A, Mullins RF, Stone EM. Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26364624 DOI: 10.1016/J.Trsl.2015.08.007  0.476
2015 Drivas TG, Wojno AP, Tucker BA, Stone EM, Bennett J. Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis. Science Translational Medicine. 7: 291ra97. PMID 26062849 DOI: 10.1126/Scitranslmed.Aaa5370  0.343
2015 Yao J, Ko CW, Baranov PY, Regatieri CV, Redenti S, Tucker BA, Mighty J, Tao SL, Young MJ. Enhanced differentiation and delivery of mouse retinal progenitor cells using a micropatterned biodegradable thin-film polycaprolactone scaffold. Tissue Engineering. Part A. 21: 1247-60. PMID 25517296 DOI: 10.1089/Ten.Tea.2013.0720  0.334
2015 Wiley LA, Burnight ER, Mullins RF, Stone EM, Tucker BA. Stem cells as tools for studying the genetics of inherited retinal degenerations. Cold Spring Harbor Perspectives in Medicine. 5: a017160. PMID 25502747 DOI: 10.1101/Cshperspect.A017160  0.446
2015 Whitmore SS, Sohn EH, Chirco KR, Drack AV, Stone EM, Tucker BA, Mullins RF. Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Progress in Retinal and Eye Research. 45: 1-29. PMID 25486088 DOI: 10.1016/J.Preteyeres.2014.11.005  0.38
2015 Wiley LA, Burnight ER, Songstad AE, Drack AV, Mullins RF, Stone EM, Tucker BA. Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases. Progress in Retinal and Eye Research. 44: 15-35. PMID 25448922 DOI: 10.1016/J.Preteyeres.2014.10.002  0.434
2015 Burnight ER, Wiley LA, Mullins RF, Stone EM, Tucker BA. Gene therapy using stem cells. Cold Spring Harbor Perspectives in Medicine. 5. PMID 25395375 DOI: 10.1101/Cshperspect.A017434  0.381
2015 Maeder ML, Shen S, Burnight ER, Gloskowski S, Mepani R, Friedland AE, Jayaram H, Gotta G, Tucker BA, Bumcrot D. 687. Therapeutic Correction of an LCA-Causing Splice Defect in the CEP290 Gene by CRISPR/Cas-Mediated Genome Editing Molecular Therapy. 23: S273-S274. DOI: 10.1016/S1525-0016(16)34296-4  0.377
2014 Whitmore SS, Wagner AH, DeLuca AP, Drack AV, Stone EM, Tucker BA, Zeng S, Braun TA, Mullins RF, Scheetz TE. Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq. Experimental Eye Research. 129: 93-106. PMID 25446321 DOI: 10.1016/J.Exer.2014.11.001  0.442
2014 Mullins RF, Schoo DP, Sohn EH, Flamme-Wiese MJ, Workamelahu G, Johnston RM, Wang K, Tucker BA, Stone EM. The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning. The American Journal of Pathology. 184: 3142-53. PMID 25204844 DOI: 10.1016/J.Ajpath.2014.07.017  0.57
2014 Tucker BA, Solivan-Timpe F, Roos BR, Anfinson KR, Robin AL, Wiley LA, Mullins RF, Fingert JH. Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma. Journal of Stem Cell Research & Therapy. 3: 161. PMID 24883232 DOI: 10.4172/2157-7633.1000161  0.434
2014 Burnight ER, Wiley LA, Drack AV, Braun TA, Anfinson KR, Kaalberg EE, Halder JA, Affatigato LM, Mullins RF, Stone EM, Tucker BA. CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. Gene Therapy. 21: 662-72. PMID 24807808 DOI: 10.1038/Gt.2014.39  0.395
2014 Boye SE, Huang WC, Roman AJ, Sumaroka A, Boye SL, Ryals RC, Olivares MB, Ruan Q, Tucker BA, Stone EM, Swaroop A, Cideciyan AV, Hauswirth WW, Jacobson SG. Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy. Plos One. 9: e92928. PMID 24671090 DOI: 10.1371/Journal.Pone.0092928  0.421
2014 Mullins RF, Khanna A, Schoo DP, Tucker BA, Sohn EH, Drack AV, Stone EM. Is age-related macular degeneration a microvascular disease? Advances in Experimental Medicine and Biology. 801: 283-9. PMID 24664709 DOI: 10.1007/978-1-4614-3209-8_36  0.35
2014 Tucker BA, Mullins RF, Stone EM. Stem cells for investigation and treatment of inherited retinal disease. Human Molecular Genetics. 23: R9-R16. PMID 24647603 DOI: 10.1093/Hmg/Ddu124  0.445
2014 Worthington KS, Wiley LA, Bartlett AM, Stone EM, Mullins RF, Salem AK, Guymon CA, Tucker BA. Mechanical properties of murine and porcine ocular tissues in compression. Experimental Eye Research. 121: 194-9. PMID 24613781 DOI: 10.1016/J.Exer.2014.02.020  0.313
2014 Thompson S, Blodi FR, Lee S, Welder CR, Mullins RF, Tucker BA, Stasheff SF, Stone EM. Photoreceptor cells with profound structural deficits can support useful vision in mice. Investigative Ophthalmology & Visual Science. 55: 1859-66. PMID 24569582 DOI: 10.1167/Iovs.13-13661  0.341
2014 Sohn EH, Khanna A, Tucker BA, Abràmoff MD, Stone EM, Mullins RF. Structural and biochemical analyses of choroidal thickness in human donor eyes. Investigative Ophthalmology & Visual Science. 55: 1352-60. PMID 24519422 DOI: 10.1167/Iovs.13-13754  0.328
2014 Wojno A, Drivas T, Tucker B, Stone E, Bennett J. Basel exon skipping - a novel model of disease pathogenesis to explain CEP290-associated retinal degeneration and related ciliopathies Journal of Vision. 14: 85-85. DOI: 10.1167/14.15.85  0.404
2013 Tucker BA, Mullins RF, Streb LM, Anfinson K, Eyestone ME, Kaalberg E, Riker MJ, Drack AV, Braun TA, Stone EM. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. Elife. 2: e00824. PMID 23991284 DOI: 10.7554/Elife.00824  0.466
2013 Braun TA, Mullins RF, Wagner AH, Andorf JL, Johnston RM, Bakall BB, Deluca AP, Fishman GA, Lam BL, Weleber RG, Cideciyan AV, Jacobson SG, Sheffield VC, Tucker BA, Stone EM. Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease. Human Molecular Genetics. 22: 5136-45. PMID 23918662 DOI: 10.1093/Hmg/Ddt367  0.6
2013 Tucker BA, Anfinson KR, Mullins RF, Stone EM, Young MJ. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Translational Medicine. 2: 16-24. PMID 23283489 DOI: 10.5966/Sctm.2012-0040  0.324
2013 Tucker BA, Mullins RF, Streb LM, Anfnson K, Eyestone ME, Kaalberg E, Riker MJ, Drack AV, Braun TA, Stone EM. Patient-specifc iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa Elife. 2013. DOI: 10.7554/eLife.00824.001  0.381
2012 Velez G, Weingarden AR, Tucker BA, Lei H, Kazlauskas A, Young MJ. Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRα and Ability to Induce Proliferative Vitreoretinopathy in a Rabbit Model. Stem Cells International. 2012: 106486. PMID 22966235 DOI: 10.1155/2012/106486  0.31
2011 Tucker BA, Scheetz TE, Mullins RF, DeLuca AP, Hoffmann JM, Johnston RM, Jacobson SG, Sheffield VC, Stone EM. Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. 108: E569-76. PMID 21825139 DOI: 10.1073/Pnas.1108918108  0.607
2011 Tucker BA, Park IH, Qi SD, Klassen HJ, Jiang C, Yao J, Redenti S, Daley GQ, Young MJ. Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. Plos One. 6: e18992. PMID 21559507 DOI: 10.1371/Journal.Pone.0018992  0.377
2011 Yao J, Tucker BA, Zhang X, Checa-Casalengua P, Herrero-Vanrell R, Young MJ. Robust cell integration from co-transplantation of biodegradable MMP2-PLGA microspheres with retinal progenitor cells. Biomaterials. 32: 1041-50. PMID 21030072 DOI: 10.1016/j.biomaterials.2010.09.063  0.316
2010 Tucker BA, Redenti SM, Jiang C, Swift JS, Klassen HJ, Smith ME, Wnek GE, Young MJ. The use of progenitor cell/biodegradable MMP2-PLGA polymer constructs to enhance cellular integration and retinal repopulation. Biomaterials. 31: 9-19. PMID 19775744 DOI: 10.1016/J.Biomaterials.2009.09.015  0.319
2010 Tucker B, Young MJ, Klassen H. Cellular repopulation of the retina Ocular Disease: Mechanisms and Management. 607-611. DOI: 10.1016/B978-0-7020-2983-7.00077-2  0.312
2009 Tackenberg MA, Tucker BA, Swift JS, Jiang C, Redenti S, Greenberg KP, Flannery JG, Reichenbach A, Young MJ. Müller cell activation, proliferation and migration following laser injury. Molecular Vision. 15: 1886-96. PMID 19768129  0.305
2009 Aftab U, Jiang C, Tucker B, Kim JY, Klassen H, Miljan E, Sinden J, Young M. Growth kinetics and transplantation of human retinal progenitor cells. Experimental Eye Research. 89: 301-10. PMID 19524569 DOI: 10.1016/J.Exer.2009.03.025  0.339
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