Leon H.F. Mullenders - Publications

Affiliations: 
Leiden University, Leiden, Netherlands 
Area:
Toxicogenetics
Website:
http://www.leidenuniv.nl/professoren/show.php3-medewerker_id=779.htm

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liebelt F, Schimmel J, Verlaan-de Vries M, Klemann E, van Royen ME, van der Weegen Y, Luijsterburg MS, Mullenders LH, Pines A, Vermeulen W, Vertegaal ACO. Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation. Nucleic Acids Research. PMID 31722399 DOI: 10.1093/nar/gkz977  0.303
2018 Pines A, Dijk M, Makowski M, Meulenbroek EM, Vrouwe MG, van der Weegen Y, Baltissen M, French PJ, van Royen ME, Luijsterburg MS, Mullenders LH, Vermeulen M, Vermeulen W, Pannu NS, van Attikum H. TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A. Nature Communications. 9: 1040. PMID 29531219 DOI: 10.1038/s41467-018-03484-6  0.34
2017 Luijsterburg MS, Typas D, Caron MC, Wiegant WW, Heuvel DV, Boonen RA, Couturier AM, Mullenders LH, Masson JY, Attikum HV. A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation. Elife. 6. PMID 28240985 DOI: 10.7554/eLife.20922  0.377
2016 Evans MD, Misty V, Singh R, Gackowski D, Różalski R, Siomek-Gorecka A, Phillips DH, Zuo J, Mullenders L, Pines A, Nakabeppu Y, Sakumi K, Sekiguchi M, Tsuzuki T, Bignami M, et al. Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. Free Radical Biology & Medicine. PMID 27585947 DOI: 10.1016/j.freeradbiomed.2016.08.018  0.344
2015 Mullenders L. DNA damage mediated transcription arrest: Step back to go forward. Dna Repair. 36: 28-35. PMID 26422136 DOI: 10.1016/j.dnarep.2015.09.005  0.378
2015 Tresini M, Warmerdam DO, Kolovos P, Snijder L, Vrouwe MG, Demmers JA, van IJcken WF, Grosveld FG, Medema RH, Hoeijmakers JH, Mullenders LH, Vermeulen W, Marteijn JA. The core spliceosome as target and effector of non-canonical ATM signalling. Nature. PMID 26106861 DOI: 10.1038/nature14512  0.384
2015 Typas D, Luijsterburg MS, Wiegant WW, Diakatou M, Helfricht A, Thijssen PE, van de Broek B, Mullenders LH, van Attikum H. The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80. Nucleic Acids Research. PMID 26101254 DOI: 10.1093/nar/gkv613  0.308
2015 von Stechow L, Typas D, Carreras Puigvert J, Oort L, Siddappa R, Pines A, Vrieling H, van de Water B, Mullenders LH, Danen EH. The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest. Molecular and Cellular Biology. 35: 1254-68. PMID 25624349 DOI: 10.1128/MCB.01152-14  0.39
2014 Dijk M, Typas D, Mullenders L, Pines A. Insight in the multilevel regulation of NER. Experimental Cell Research. 329: 116-23. PMID 25128816 DOI: 10.1016/j.yexcr.2014.08.010  0.365
2014 Tsaalbi-Shtylik A, Moser J, Mullenders LH, Jansen JG, de Wind N. Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A. Nucleic Acids Research. 42: 4406-13. PMID 24464993 DOI: 10.1093/nar/gkt1412  0.391
2013 Fotouhi A, Hagos WW, Ilic M, Wojcik A, Harms-Ringdahl M, de Gruijl F, Mullenders L, Jansen JG, Haghdoost S. Analysis of mutant frequencies and mutation spectra in hMTH1 knockdown TK6 cells exposed to UV radiation. Mutation Research. 751: 8-14. PMID 24144844 DOI: 10.1016/j.mrfmmm.2013.10.001  0.325
2013 Pines A, Mullenders LH, van Attikum H, Luijsterburg MS. Touching base with PARPs: moonlighting in the repair of UV lesions and double-strand breaks. Trends in Biochemical Sciences. 38: 321-30. PMID 23562323 DOI: 10.1016/j.tibs.2013.03.002  0.378
2013 Carreras Puigvert J, von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC, Olsen JV, Vrieling H, Meerman JH, Mullenders LH, van de Water B, Danen EH. Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells. Science Signaling. 6: ra5. PMID 23354688 DOI: 10.1126/scisignal.2003208  0.376
2012 Pines A, Vrouwe MG, Marteijn JA, Typas D, Luijsterburg MS, Cansoy M, Hensbergen P, Deelder A, de Groot A, Matsumoto S, Sugasawa K, Thoma N, Vermeulen W, Vrieling H, Mullenders L. PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1. The Journal of Cell Biology. 199: 235-49. PMID 23045548 DOI: 10.1083/jcb.201112132  0.364
2012 Luijsterburg MS, Lindh M, Acs K, Vrouwe MG, Pines A, van Attikum H, Mullenders LH, Dantuma NP. DDB2 promotes chromatin decondensation at UV-induced DNA damage. The Journal of Cell Biology. 197: 267-81. PMID 22492724 DOI: 10.1083/jcb.201106074  0.376
2012 Cramers P, Filon AR, Pines A, Kleinjans JC, Mullenders LH, van Zeeland AA. Enhanced nucleotide excision repair in human fibroblasts pre-exposed to ionizing radiation. Photochemistry and Photobiology. 88: 147-53. PMID 22017241 DOI: 10.1111/j.1751-1097.2011.01019.x  0.354
2012 Mullenders L. DNA Damage Response in UV Irradiated Cells Qscience Proceedings. 2012: 62. DOI: 10.5339/qproc.2012.mutagens.3.62  0.399
2011 Melis JP, Luijten M, Mullenders LH, van Steeg H. The role of XPC: implications in cancer and oxidative DNA damage. Mutation Research. 728: 107-17. PMID 21763452 DOI: 10.1016/j.mrrev.2011.07.001  0.446
2011 Lagerwerf S, Vrouwe MG, Overmeer RM, Fousteri MI, Mullenders LH. DNA damage response and transcription. Dna Repair. 10: 743-50. PMID 21622031 DOI: 10.1016/j.dnarep.2011.04.024  0.478
2011 Tanori M, Pasquali E, Leonardi S, Giardullo P, Di Majo V, Taccioli G, Essers J, Kanaar R, Mullenders LH, Atkinson MJ, Mancuso M, Saran A, Pazzaglia S. Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum. Oncogene. 30: 4740-9. PMID 21602895 DOI: 10.1038/onc.2011.178  0.44
2011 Cramers P, Verhoeven EE, Filon AR, Rockx DA, Santos SJ, van der Leer AA, Kleinjans JC, van Zeeland AA, Mullenders LH. Impaired repair of ionizing radiation-induced DNA damage in Cockayne syndrome cells. Radiation Research. 175: 432-43. PMID 21299404 DOI: 10.1667/RR1972.1  0.396
2011 Overmeer RM, Moser J, Volker M, Kool H, Tomkinson AE, van Zeeland AA, Mullenders LH, Fousteri M. Replication protein A safeguards genome integrity by controlling NER incision events. The Journal of Cell Biology. 192: 401-15. PMID 21282463 DOI: 10.1083/Jcb.201006011  0.486
2011 Vrouwe MG, Pines A, Overmeer RM, Hanada K, Mullenders LH. UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways. Journal of Cell Science. 124: 435-46. PMID 21224401 DOI: 10.1242/Jcs.075325  0.485
2010 Hendriks G, Jansen JG, Mullenders LH, de Wind N. Transcription-coupled repair and apoptosis provide specific protection against transcription-associated mutagenesis by ultraviolet light. Transcription. 1: 95-8. PMID 21326899 DOI: 10.4161/trns.1.2.12788  0.393
2010 Overmeer RM, Gourdin AM, Giglia-Mari A, Kool H, Houtsmuller AB, Siegal G, Fousteri MI, Mullenders LH, Vermeulen W. Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment. Molecular and Cellular Biology. 30: 4828-39. PMID 20713449 DOI: 10.1128/MCB.00285-10  0.385
2010 Anindya R, Mari PO, Kristensen U, Kool H, Giglia-Mari G, Mullenders LH, Fousteri M, Vermeulen W, Egly JM, Svejstrup JQ. A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair. Molecular Cell. 38: 637-48. PMID 20541997 DOI: 10.1016/J.Molcel.2010.04.017  0.351
2010 Hendriks G, Jansen JG, Mullenders LH, de Wind N. Transcription and replication: far relatives make uneasy bedfellows. Cell Cycle (Georgetown, Tex.). 9: 2300-4. PMID 20519944 DOI: 10.4161/Cc.9.12.11987  0.425
2010 Grosskopf C, Schwerdtle T, Mullenders LH, Hartwig A. Antimony impairs nucleotide excision repair: XPA and XPE as potential molecular targets. Chemical Research in Toxicology. 23: 1175-83. PMID 20509621 DOI: 10.1021/Tx100106X  0.49
2010 Smeenk G, de Groot AJ, Romeijn RJ, van Buul PP, Zdzienicka MZ, Mullenders LH, Pastink A, Godthelp BC. Rad51C is essential for embryonic development and haploinsufficiency causes increased DNA damage sensitivity and genomic instability. Mutation Research. 689: 50-8. PMID 20471405 DOI: 10.1016/j.mrfmmm.2010.05.001  0.417
2010 Ogi T, Limsirichaikul S, Overmeer RM, Volker M, Takenaka K, Cloney R, Nakazawa Y, Niimi A, Miki Y, Jaspers NG, Mullenders LH, Yamashita S, Fousteri MI, Lehmann AR. Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Molecular Cell. 37: 714-27. PMID 20227374 DOI: 10.1016/J.Molcel.2010.02.009  0.41
2010 Schwerdtle T, Ebert F, Thuy C, Richter C, Mullenders LH, Hartwig A. Genotoxicity of soluble and particulate cadmium compounds: impact on oxidative DNA damage and nucleotide excision repair. Chemical Research in Toxicology. 23: 432-42. PMID 20092276 DOI: 10.1021/Tx900444W  0.466
2010 Wiegant WW, Meyers M, Verkaik NS, van der Burg M, Darroudi F, Romeijn R, Bernatowska E, Wolska-Kusnierz B, Mikoluc B, Jaspers NG, Vreeken C, Ijspeert H, Esveldt-van Lange RE, Friedl AA, de Villartay JP, ... Mullenders LH, et al. A novel radiosensitive SCID patient with a pronounced G(2)/M sensitivity. Dna Repair. 9: 365-73. PMID 20079696 DOI: 10.1016/j.dnarep.2009.12.004  0.301
2010 Hendriks G, Calléja F, Besaratinia A, Vrieling H, Pfeifer GP, Mullenders LH, Jansen JG, de Wind N. Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis. Current Biology : Cb. 20: 170-5. PMID 20045328 DOI: 10.1016/j.cub.2009.11.061  0.36
2009 Luijsterburg MS, Dinant C, Lans H, Stap J, Wiernasz E, Lagerwerf S, Warmerdam DO, Lindh M, Brink MC, Dobrucki JW, Aten JA, Fousteri MI, Jansen G, Dantuma NP, Vermeulen W, ... Mullenders LH, et al. Heterochromatin protein 1 is recruited to various types of DNA damage. The Journal of Cell Biology. 185: 577-86. PMID 19451271 DOI: 10.1083/jcb.200810035  0.4
2009 Episkopou H, Kyrtopoulos SA, Sfikakis PP, Fousteri M, Dimopoulos MA, Mullenders LH, Souliotis VL. Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts. Cancer Research. 69: 4424-33. PMID 19417135 DOI: 10.1158/0008-5472.Can-08-3489  0.416
2009 Nollen M, Ebert F, Moser J, Mullenders LH, Hartwig A, Schwerdtle T. Impact of arsenic on nucleotide excision repair: XPC function, protein level, and gene expression. Molecular Nutrition & Food Research. 53: 572-82. PMID 19382146 DOI: 10.1002/mnfr.200800480  0.308
2009 Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B. Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nature Cell Biology. 11: 604-15. PMID 19363488 DOI: 10.1038/Ncb1866  0.413
2009 Jansen JG, Tsaalbi-Shtylik A, Hendriks G, Gali H, Hendel A, Johansson F, Erixon K, Livneh Z, Mullenders LH, Haracska L, de Wind N. Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells. Molecular and Cellular Biology. 29: 3113-23. PMID 19332561 DOI: 10.1128/Mcb.00071-09  0.497
2009 Vreeswijk MP, Meijers CM, Giphart-Gassler M, Vrieling H, van Zeeland AA, Mullenders LH, Loenen WA. Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra. Mutation Research. 663: 7-14. PMID 19150617 DOI: 10.1016/j.mrfmmm.2008.12.007  0.312
2009 Pines A, Backendorf C, Alekseev S, Jansen JG, de Gruijl FR, Vrieling H, Mullenders LH. Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer. Dna Repair. 8: 153-61. PMID 18996499 DOI: 10.1016/j.dnarep.2008.09.011  0.338
2008 Alekseev S, Luijsterburg MS, Pines A, Geverts B, Mari PO, Giglia-Mari G, Lans H, Houtsmuller AB, Mullenders LH, Hoeijmakers JH, Vermeulen W. Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage. Molecular and Cellular Biology. 28: 7402-13. PMID 18936169 DOI: 10.1128/MCB.01108-08  0.418
2008 Hendriks G, Calléja F, Vrieling H, Mullenders LH, Jansen JG, de Wind N. Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells. Dna Repair. 7: 1330-9. PMID 18539547 DOI: 10.1016/j.dnarep.2008.04.015  0.435
2008 Fousteri M, Mullenders LH. Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects. Cell Research. 18: 73-84. PMID 18166977 DOI: 10.1038/cr.2008.6  0.425
2007 Moser J, Kool H, Giakzidis I, Caldecott K, Mullenders LH, Fousteri MI. Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner. Molecular Cell. 27: 311-23. PMID 17643379 DOI: 10.1016/J.Molcel.2007.06.014  0.459
2007 Luijsterburg MS, Goedhart J, Moser J, Kool H, Geverts B, Houtsmuller AB, Mullenders LH, Vermeulen W, van Driel R. Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC. Journal of Cell Science. 120: 2706-16. PMID 17635991 DOI: 10.1242/Jcs.008367  0.466
2007 Vrouwe MG, Elghalbzouri-Maghrani E, Meijers M, Schouten P, Godthelp BC, Bhuiyan ZA, Redeker EJ, Mannens MM, Mullenders LH, Pastink A, Darroudi F. Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair. Human Molecular Genetics. 16: 1478-87. PMID 17468178 DOI: 10.1093/hmg/ddm098  0.45
2007 Stoilov LM, Mullenders LH, Darroudi F, Natarajan AT. Adaptive response to DNA and chromosomal damage induced by X-rays in human blood lymphocytes. Mutagenesis. 22: 117-22. PMID 17229819 DOI: 10.1093/Mutage/Gel061  0.439
2007 Nijhof JG, van Pelt C, Mulder AA, Mitchell DL, Mullenders LH, de Gruijl FR. Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency. Carcinogenesis. 28: 792-800. PMID 17127714 DOI: 10.1093/Carcin/Bgl213  0.47
2007 van der Wees C, Jansen J, Vrieling H, van der Laarse A, Van Zeeland A, Mullenders L. Nucleotide excision repair in differentiated cells Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 614: 16-23. PMID 16879838 DOI: 10.1016/j.mrfmmm.2006.06.005  0.365
2006 Fousteri M, Vermeulen W, van Zeeland AA, Mullenders LH. Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo. Molecular Cell. 23: 471-82. PMID 16916636 DOI: 10.1016/j.molcel.2006.06.029  0.332
2006 van Haaften G, Romeijn R, Pothof J, Koole W, Mullenders LH, Pastink A, Plasterk RH, Tijsterman M. Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi. Current Biology : Cb. 16: 1344-50. PMID 16824923 DOI: 10.1016/J.Cub.2006.05.047  0.35
2006 Abdel-Halim HI, Mullenders LH, Boei JJ. Pairing of heterochromatin in response to cellular stress. Experimental Cell Research. 312: 1961-9. PMID 16626698 DOI: 10.1016/j.yexcr.2006.02.028  0.365
2006 van Schanke A, van Venrooij GM, Jongsma MJ, Banus HA, Mullenders LH, van Kranen HJ, de Gruijl FR. Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposures. Cancer Research. 66: 2608-15. PMID 16510579 DOI: 10.1158/0008-5472.Can-05-2476  0.326
2005 Stout GJ, Westdijk D, Calkhoven DM, Pijper O, Backendorf CM, Willemze R, Mullenders LH, de Gruijl FR. Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: an alternative to in situ apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18980-5. PMID 16365302 DOI: 10.1073/Pnas.0505505102  0.472
2005 Alekseev S, Kool H, Rebel H, Fousteri M, Moser J, Backendorf C, de Gruijl FR, Vrieling H, Mullenders LH. Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation. Cancer Research. 65: 10298-306. PMID 16288018 DOI: 10.1158/0008-5472.Can-05-2295  0.44
2005 Cramers P, Atanasova P, Vrolijk H, Darroudi F, van Zeeland AA, Huiskamp R, Mullenders LH, Kleinjans JC. Pre-exposure to low doses: modulation of X-ray-induced dna damage and repair? Radiation Research. 164: 383-90. PMID 16187740 DOI: 10.1667/RR3430.1  0.391
2005 Backendorf C, de Wit J, van Oosten M, Stout GJ, Mitchell JR, Borgstein AM, van der Horst GT, de Gruijl FR, Brouwer J, Mullenders LH, Hoeijmakers JH. Repair characteristics and differentiation propensity of long-term cultures of epidermal keratinocytes derived from normal and NER-deficient mice. Dna Repair. 4: 1325-36. PMID 16182615 DOI: 10.1016/J.Dnarep.2005.07.011  0.334
2005 Stout GJ, Oosten Mv, Acherrat FZ, Wit Jd, Vermeij WP, Mullenders LH, Gruijl FR, Backendorf C. Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures. Dna Repair. 4: 1337-44. PMID 16182614 DOI: 10.1016/J.Dnarep.2005.07.012  0.488
2005 Theron T, Fousteri MI, Volker M, Harries LW, Botta E, Stefanini M, Fujimoto M, Andressoo JO, Mitchell J, Jaspers NG, McDaniel LD, Mullenders LH, Lehmann AR. Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome. Molecular and Cellular Biology. 25: 8368-78. PMID 16135823 DOI: 10.1128/Mcb.25.18.8368-8378.2005  0.345
2005 Hamdi M, Kool J, Cornelissen-Steijger P, Carlotti F, Popeijus HE, van der Burgt C, Janssen JM, Yasui A, Hoeben RC, Terleth C, Mullenders LH, van Dam H. DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1. Oncogene. 24: 7135-44. PMID 16044158 DOI: 10.1038/sj.onc.1208875  0.377
2005 Fousteri M, van Hoffen A, Vargova H, Mullenders LH. Repair of DNA lesions in chromosomal DNA impact of chromatin structure and Cockayne syndrome proteins. Dna Repair. 4: 919-25. PMID 15961352 DOI: 10.1016/J.Dnarep.2005.04.011  0.508
2005 Moser J, Volker M, Kool H, Alekseev S, Vrieling H, Yasui A, van Zeeland AA, Mullenders LH. The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions. Dna Repair. 4: 571-82. PMID 15811629 DOI: 10.1016/j.dnarep.2005.01.001  0.404
2005 Abdel-Halim HI, Natarajan AT, Mullenders LH, Boei JJ. Mitomycin C-induced pairing of heterochromatin reflects initiation of DNA repair and chromatid exchange formation. Journal of Cell Science. 118: 1757-67. PMID 15797924 DOI: 10.1242/jcs.02306  0.307
2005 Romeijn RJ, Gorski MM, van Schie MA, Noordermeer JN, Mullenders LH, Ferro W, Pastink A. Lig4 and rad54 are required for repair of DNA double-strand breaks induced by P-element excision in Drosophila. Genetics. 169: 795-806. PMID 15545651 DOI: 10.1534/genetics.104.033464  0.31
2005 van Oosten M, Stout GJ, Backendorf C, Rebel H, de Wind N, Darroudi F, van Kranen HJ, de Gruijl FR, Mullenders LH. Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes. Dna Repair. 4: 81-9. PMID 15533840 DOI: 10.1016/j.dnarep.2004.08.008  0.382
2004 Kobayashi K, O'Driscoll M, Macpherson P, Mullenders L, Vreeswijk M, Karran P. XPC lymphoblastoid cells defective in the hMutSα DNA mismatch repair complex exhibit normal sensitivity to UVC radiation and normal transcription-coupled excision repair of DNA cyclobutane pyrimidine dimers Dna Repair. 3: 649-657. PMID 15135732 DOI: 10.1016/j.dnarep.2004.02.007  0.445
2004 Gorski MM, Romeijn RJ, Eeken JC, de Jong AW, van Veen BL, Szuhai K, Mullenders LH, Ferro W, Pastink A. Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae. Dna Repair. 3: 603-15. PMID 15135728 DOI: 10.1016/j.dnarep.2004.02.001  0.394
2004 Riou L, Eveno E, van Hoffen A, van Zeeland AA, Sarasin A, Mullenders LH. Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts. Cancer Research. 64: 889-94. PMID 14871817 DOI: 10.1158/0008-5472.Can-03-2070  0.483
2003 Gorski MM, Eeken JC, de Jong AW, Klink I, Loos M, Romeijn RJ, van Veen BL, Mullenders LH, Ferro W, Pastink A. The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54. Genetics. 165: 1929-41. PMID 14704177  0.388
2003 van der Wees CG, Vreeswijk MP, Persoon M, van der Laarse A, van Zeeland AA, Mullenders LH. Deficient global genome repair of UV-induced cyclobutane pyrimidine dimers in terminally differentiated myocytes and proliferating fibroblasts from the rat heart. Dna Repair. 2: 1297-308. PMID 14642560 DOI: 10.1016/j.dnarep.2003.06.001  0.393
2003 van Hoffen A, Balajee AS, van Zeeland AA, Mullenders LH. Nucleotide excision repair and its interplay with transcription. Toxicology. 193: 79-90. PMID 14599769 DOI: 10.1016/j.tox.2003.06.001  0.448
2003 van Gijssel HE, Mullenders LH, van Oosterwijk MF, Meerman JH. Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts. Life Sciences. 73: 1759-71. PMID 12888115 DOI: 10.1016/S0024-3205(03)00506-X  0.32
2002 Hoogstraten D, Nigg AL, Heath H, Mullenders LH, van Driel R, Hoeijmakers JH, Vermeulen W, Houtsmuller AB. Rapid switching of TFIIH between RNA polymerase I and II transcription and DNA repair in vivo. Molecular Cell. 10: 1163-74. PMID 12453423 DOI: 10.1016/S1097-2765(02)00709-8  0.393
2002 Buterin T, Hess MT, Gunz D, Geacintov NE, Mullenders LH, Naegeli H. Trapping of DNA nucleotide excision repair factors by nonrepairable carcinogen adducts. Cancer Research. 62: 4229-35. PMID 12154024 DOI: 10.5167/Uzh-14526  0.412
2002 Surrallés J, Ramírez MJ, Marcos R, Natarajan AT, Mullenders LH. Clusters of transcription-coupled repair in the human genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 10571-4. PMID 12142466 DOI: 10.1073/Pnas.162278199  0.446
2001 Moné MJ, Volker M, Nikaido O, Mullenders LH, van Zeeland AA, Verschure PJ, Manders EM, van Driel R. Local UV-induced DNA damage in cell nuclei results in local transcription inhibition. Embo Reports. 2: 1013-7. PMID 11713193 DOI: 10.1093/embo-reports/kve224  0.389
2001 de Gruijl FR, van Kranen HJ, Mullenders LH. UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. Journal of Photochemistry and Photobiology. B, Biology. 63: 19-27. PMID 11684448 DOI: 10.1016/S1011-1344(01)00199-3  0.422
2001 Volker M, Moné MJ, Karmakar P, van Hoffen A, Schul W, Vermeulen W, Hoeijmakers JH, van Driel R, van Zeeland AA, Mullenders LH. Sequential assembly of the nucleotide excision repair factors in vivo. Molecular Cell. 8: 213-24. PMID 11511374 DOI: 10.1016/S1097-2765(01)00281-7  0.307
2001 Wijnhoven SW, Kool HJ, Mullenders LH, Slater R, van Zeeland AA, Vrieling H. DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa, Xpc and Csb mice. Carcinogenesis. 22: 1099-106. PMID 11408355 DOI: 10.1093/Carcin/22.7.1099  0.382
2001 van Zeeland AA, Mullenders LH, Vrieling H. Gene and sequence specificity of DNA damage induction and repair: consequences for mutagenesis. Mutation Research. 485: 15-21. PMID 11341990 DOI: 10.1016/S0921-8777(00)00072-0  0.401
2001 Sonneveld E, Vrieling H, Mullenders LH, van Hoffen A. Mouse mismatch repair gene Msh2 is not essential for transcription-coupled repair of UV-induced cyclobutane pyrimidine dimers. Oncogene. 20: 538-41. PMID 11313985 DOI: 10.1038/sj.onc.1204125  0.428
2001 Jansen J, Olsen AK, Wiger R, Naegeli H, de Boer P, van Der Hoeven F, Holme JA, Brunborg G, Mullenders L. Nucleotide excision repair in rat male germ cells: low level of repair in intact cells contrasts with high dual incision activity in vitro. Nucleic Acids Research. 29: 1791-800. PMID 11292852 DOI: 10.1093/nar/29.8.1791  0.371
2001 Kannouche P, Broughton BC, Volker M, Hanaoka F, Mullenders LH, Lehmann AR. Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Genes & Development. 15: 158-72. PMID 11157773 DOI: 10.1101/Gad.187501  0.444
2000 Wijnhoven SW, Kool HJ, Mullenders LH, van Zeeland AA, Friedberg EC, van der Horst GT, van Steeg H, Vrieling H. Age-dependent spontaneous mutagenesis in Xpc mice defective in nucleotide excision repair. Oncogene. 19: 5034-7. PMID 11042691 DOI: 10.1038/Sj.Onc.1203844  0.432
2000 van Oosten M, Rebel H, Friedberg EC, van Steeg H, van der Horst GT, van Kranen HJ, Westerman A, van Zeeland AA, Mullenders LH, de Gruijl FR. Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11268-73. PMID 11005836 DOI: 10.1073/Pnas.200226697  0.444
2000 Rockx DA, Mason R, van Hoffen A, Barton MC, Citterio E, Bregman DB, van Zeeland AA, Vrieling H, Mullenders LH. UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 97: 10503-8. PMID 10973477 DOI: 10.1073/Pnas.180169797  0.429
2000 Asmuss M, Mullenders LH, Hartwig A. Interference by toxic metal compounds with isolated zinc finger DNA repair proteins. Toxicology Letters. 112: 227-31. PMID 10720735 DOI: 10.1016/S0378-4274(99)00273-8  0.389
1999 Van Sloun PP, Jansen JG, Weeda G, Mullenders LH, van Zeeland AA, Lohman PH, Vrieling H. The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage. Nucleic Acids Research. 27: 3276-82. PMID 10454634  0.371
1999 van Hoffen A, Kalle WH, de Jong-Versteeg A, Lehmann AR, van Zeeland AA, Mullenders LH. Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription. Nucleic Acids Research. 27: 2898-904. PMID 10390531 DOI: 10.1093/Nar/27.14.2898  0.413
1998 Abrahams PJ, Houweling A, Cornelissen-Steijger PD, Jaspers NG, Darroudi F, Meijers CM, Mullenders LH, Filon R, Arwert F, Pinedo HM, Natarajan AP, Terleth C, Van Zeeland AA, van der Eb AJ. Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes. Mutation Research. 407: 189-201. PMID 9637247 DOI: 10.1016/S0921-8777(98)00009-3  0.416
1998 Hartwig A, Mullenders L, Asmuß M, Dally H, Hartmann M. Disruption of DNA repair processes by carcinogenic metal compounds Fresenius Journal of Analytical Chemistry. 361: 377-380. DOI: 10.1007/S002160050909  0.387
1997 Cheo DL, Ruven HJ, Meira LB, Hammer RE, Burns DK, Tappe NJ, van Zeeland AA, Mullenders LH, Friedberg EC. Characterization of defective nucleotide excision repair in XPC mutant mice. Mutation Research. 374: 1-9. PMID 9067411 DOI: 10.1016/S0027-5107(97)00046-8  0.465
1997 Mullenders LH, van Hoffen A, Vreeswijk MP, Ruven HJ, Vrieling H, van Zeeland AA. Ultraviolet-induced photolesions: repair and mutagenesis Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 143: 89-99. PMID 8912414 DOI: 10.1007/978-3-642-60393-8_7  0.429
1992 Wiegant J, Kalle W, Mullenders L, Brookes S, Hoovers JMN, Dauwerse JG, Van Ommen GJB, Raap AK. High-resolution in situ hybridization using DNA halo preparations Human Molecular Genetics. 1: 587-591. PMID 1301167 DOI: 10.1093/Hmg/1.8.587  0.397
1990 van Zeeland AA, Vrieling H, van Rooijen ML, Venema J, Zdzienicka MZ, Simons JW, Mullenders LH, Lohman PH. Influence of DNA excision repair on UV-induced mutation spectra in Chinese hamster cells Progress in Clinical and Biological Research. 340: 249-254. PMID 2388913  0.371
1990 Mullenders LH, Venema J, van Hoffen A, Mayne LV, Natarajan AT, van Zeeland AA. The role of the nuclear matrix in DNA repair Progress in Clinical and Biological Research. 340: 223-232. PMID 2388911  0.326
1989 Van Zeeland AA, Mohn GR, Mullenders LH, Natarajan AT, Nivard M, Simons JW, Venema J, Vogel EW, Vrieling H, Zdzienicka MZ. Relationship between DNA-adduct formation, DNA repair, mutation frequency and mutation spectra. Annali Dell'Istituto Superiore Di Sanitã . 25: 223-8. PMID 2665602  0.357
1985 Sankaranarayanan K, Natarajan AT, Mullenders LH, van Rijn JL. Effects of pre-treatment with sodium butyrate on the frequencies of X-ray-induced chromosomal aberrations in human peripheral blood lymphocytes. Mutation Research. 151: 269-74. PMID 4033680 DOI: 10.1016/0027-5107(85)90079-X  0.404
1984 Zwanenburg TS, Mullenders LH, Natarajan AT, van Zeeland AA. Induction of DNA lesions, chromosomal aberrations, and G2 delay by bromo- and chlorodeoxyuridine Basic Life Sciences. 29: 69-82. PMID 6442573 DOI: 10.1007/978-1-4684-4889-4_5  0.374
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