| Year |
Citation |
Score |
| 2018 |
Kühnle S, Martinez-Noël G, Leclere F, Hayes SD, Harper JW, Howley PM. Angelman syndrome-associated point mutations in the Zn-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome. The Journal of Biological Chemistry. PMID 30257870 DOI: 10.1074/Jbc.Ra118.004653 |
0.309 |
|
| 2018 |
Bentley P, Tan MJA, McBride AA, White EA, Howley PM. The SMC5/6 complex interacts with the papillomavirus E2 protein and influences maintenance of viral episomal DNA. Journal of Virology. PMID 29848583 DOI: 10.1128/Jvi.00356-18 |
0.486 |
|
| 2018 |
Martínez-Noël G, Luck K, Kühnle S, Desbuleux A, Szajner P, Galligan JT, Rodriguez D, Zheng L, Boyland K, Leclere F, Zhong Q, Hill DE, Vidal M, Howley PM. Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes. Journal of Molecular Biology. PMID 29426014 DOI: 10.1016/J.Jmb.2018.01.021 |
0.366 |
|
| 2017 |
Chiang C, Pauli EK, Biryukov J, Feister KF, Meng M, White EA, Münger K, Howley PM, Meyers C, Gack MU. The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling. Journal of Virology. PMID 29263274 DOI: 10.1128/Jvi.01737-17 |
0.408 |
|
| 2017 |
Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, ... ... Howley PM, et al. Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. Plos Pathogens. 13: e1006668. PMID 29028833 DOI: 10.1371/Journal.Ppat.1006668 |
0.359 |
|
| 2016 |
White EA, Münger K, Howley PM. High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation. Mbio. 7. PMID 27651363 DOI: 10.1128/Mbio.01530-16 |
0.435 |
|
| 2015 |
Howley PM, Pfister HJ. Beta genus papillomaviruses and skin cancer. Virology. 479: 290-6. PMID 25724416 DOI: 10.1016/J.Virol.2015.02.004 |
0.326 |
|
| 2015 |
White EA, Kramer RE, Hwang JH, Pores Fernando AT, Naetar N, Hahn WC, Roberts TM, Schaffhausen BS, Livingston DM, Howley PM. Papillomavirus E7 oncoproteins share functions with polyomavirus small T antigens. Journal of Virology. 89: 2857-65. PMID 25540383 DOI: 10.1128/Jvi.03282-14 |
0.462 |
|
| 2015 |
Galligan JT, Martinez-Noël G, Arndt V, Hayes S, Chittenden TW, Harper JW, Howley PM. Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2. Journal of Proteome Research. 14: 953-66. PMID 25476789 DOI: 10.1021/Pr501005V |
0.348 |
|
| 2014 |
Vieira VC, Leonard B, White EA, Starrett GJ, Temiz NA, Lorenz LD, Lee D, Soares MA, Lambert PF, Howley PM, Harris RS. Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B. Mbio. 5. PMID 25538195 DOI: 10.1128/Mbio.02234-14 |
0.795 |
|
| 2014 |
Smith JA, Haberstroh FS, White EA, Livingston DM, DeCaprio JA, Howley PM. SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter. Virology. 468: 311-21. PMID 25222147 DOI: 10.1016/J.Virol.2014.08.022 |
0.44 |
|
| 2014 |
French CA, Rahman S, Walsh EM, Kühnle S, Grayson AR, Lemieux ME, Grunfeld N, Rubin BP, Antonescu CR, Zhang S, Venkatramani R, Dal Cin P, Howley PM. NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism. Cancer Discovery. 4: 928-41. PMID 24875858 DOI: 10.1158/2159-8290.Cd-14-0014 |
0.742 |
|
| 2014 |
White EA, Walther J, Javanbakht H, Howley PM. Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes. Journal of Virology. 88: 8201-12. PMID 24850740 DOI: 10.1128/Jvi.01197-14 |
0.422 |
|
| 2014 |
Walsh E, Kuhnle S, Rahman S, Lemieux M, Howley P, French C. Abstract 2476: A novel NUT translocation partner binds to BRD4 and is necessary for the blockade of differentiation in NUT midline carcinoma Cancer Research. 74: 2476-2476. DOI: 10.1158/1538-7445.Am2014-2476 |
0.769 |
|
| 2013 |
White EA, Howley PM. Proteomic approaches to the study of papillomavirus-host interactions. Virology. 435: 57-69. PMID 23217616 DOI: 10.1016/J.Virol.2012.09.046 |
0.365 |
|
| 2012 |
White EA, Kramer RE, Tan MJ, Hayes SD, Harper JW, Howley PM. Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity. Journal of Virology. 86: 13174-86. PMID 23015706 DOI: 10.1128/Jvi.02172-12 |
0.457 |
|
| 2012 |
Martínez-Noël G, Galligan JT, Sowa ME, Arndt V, Overton TM, Harper JW, Howley PM. Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Molecular and Cellular Biology. 32: 3095-106. PMID 22645313 DOI: 10.1128/Mcb.00201-12 |
0.399 |
|
| 2012 |
Tan MJ, White EA, Sowa ME, Harper JW, Aster JC, Howley PM. Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: E1473-80. PMID 22547818 DOI: 10.1073/Pnas.1205991109 |
0.404 |
|
| 2012 |
White EA, Sowa ME, Tan MJ, Jeudy S, Hayes SD, Santha S, Münger K, Harper JW, Howley PM. Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. Proceedings of the National Academy of Sciences of the United States of America. 109: E260-7. PMID 22232672 DOI: 10.1073/Pnas.1116776109 |
0.431 |
|
| 2011 |
Rahman S, Sowa ME, Ottinger M, Smith JA, Shi Y, Harper JW, Howley PM. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Molecular and Cellular Biology. 31: 2641-52. PMID 21555454 DOI: 10.1128/Mcb.01341-10 |
0.761 |
|
| 2010 |
Powell ML, Smith JA, Sowa ME, Harper JW, Iftner T, Stubenrauch F, Howley PM. NCoR1 mediates papillomavirus E8;E2C transcriptional repression. Journal of Virology. 84: 4451-60. PMID 20181716 DOI: 10.1128/Jvi.02390-09 |
0.458 |
|
| 2010 |
Smith JA, White EA, Sowa ME, Powell ML, Ottinger M, Harper JW, Howley PM. Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. Proceedings of the National Academy of Sciences of the United States of America. 107: 3752-7. PMID 20133580 DOI: 10.1073/Pnas.0914818107 |
0.465 |
|
| 2009 |
Fradet-Turcotte A, Brault K, Titolo S, Howley PM, Archambault J. Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9. Virology. 395: 190-201. PMID 19836047 DOI: 10.1016/J.Virol.2009.09.020 |
0.449 |
|
| 2009 |
Ottinger M, Smith JA, Schweiger MR, Robbins D, Powell ML, You J, Howley PM. Cell-type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2. Virology. 395: 161-71. PMID 19836046 DOI: 10.1016/J.Virol.2009.09.027 |
0.449 |
|
| 2009 |
You J, Li Q, Wu C, Kim J, Ottinger M, Howley PM. Regulation of aurora B expression by the bromodomain protein Brd4. Molecular and Cellular Biology. 29: 5094-103. PMID 19596781 DOI: 10.1128/Mcb.00299-09 |
0.302 |
|
| 2009 |
Zheng G, Schweiger MR, Martinez-Noel G, Zheng L, Smith JA, Harper JW, Howley PM. Brd4 regulation of papillomavirus protein E2 stability. Journal of Virology. 83: 8683-92. PMID 19553317 DOI: 10.1128/Jvi.00674-09 |
0.489 |
|
| 2009 |
Vos RM, Altreuter J, White EA, Howley PM. The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability. Journal of Virology. 83: 8885-92. PMID 19553310 DOI: 10.1128/Jvi.00605-09 |
0.475 |
|
| 2009 |
Howley PM, Livingston DM. Small DNA tumor viruses: large contributors to biomedical sciences. Virology. 384: 256-9. PMID 19136134 DOI: 10.1016/J.Virol.2008.12.006 |
0.338 |
|
| 2008 |
Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y. CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation Molecular Cell. 32: 718-726. PMID 19061646 DOI: 10.1016/J.Molcel.2008.10.025 |
0.304 |
|
| 2008 |
Goh AM, Walters KJ, Elsasser S, Verma R, Deshaies RJ, Finley D, Howley PM. Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins. Bmc Biochemistry. 9: 4. PMID 18234089 DOI: 10.1186/1471-2091-9-4 |
0.358 |
|
| 2007 |
Schweiger MR, Ottinger M, You J, Howley PM. Brd4-independent transcriptional repression function of the papillomavirus e2 proteins. Journal of Virology. 81: 9612-22. PMID 17626100 DOI: 10.1128/Jvi.00447-07 |
0.485 |
|
| 2007 |
DeMasi J, Chao MC, Kumar AS, Howley PM. Bovine papillomavirus E7 oncoprotein inhibits anoikis. Journal of Virology. 81: 9419-25. PMID 17596310 DOI: 10.1128/Jvi.00422-07 |
0.433 |
|
| 2006 |
You J, Srinivasan V, Denis GV, Harrington WJ, Ballestas ME, Kaye KM, Howley PM. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes. Journal of Virology. 80: 8909-19. PMID 16940503 DOI: 10.1128/Jvi.00502-06 |
0.35 |
|
| 2006 |
Schweiger MR, You J, Howley PM. Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function. Journal of Virology. 80: 4276-85. PMID 16611886 DOI: 10.1128/Jvi.80.9.4276-4285.2006 |
0.501 |
|
| 2006 |
Nishimura A, Nakahara T, Ueno T, Sasaki K, Yoshida S, Kyo S, Howley PM, Sakai H. Requirement of E7 oncoprotein for viability of HeLa cells. Microbes and Infection / Institut Pasteur. 8: 984-93. PMID 16500131 DOI: 10.1016/J.Micinf.2005.10.015 |
0.461 |
|
| 2006 |
Li L, Li Z, Howley PM, Sacks DB. E6AP and calmodulin reciprocally regulate estrogen receptor stability. The Journal of Biological Chemistry. 281: 1978-85. PMID 16314411 DOI: 10.1074/Jbc.M508545200 |
0.305 |
|
| 2005 |
You J, Schweiger MR, Howley PM. Inhibition of E2 binding to Brd4 enhances viral genome loss and phenotypic reversion of bovine papillomavirus-transformed cells. Journal of Virology. 79: 14956-61. PMID 16282494 DOI: 10.1128/Jvi.79.23.14956-14961.2005 |
0.429 |
|
| 2005 |
DeMasi J, Huh KW, Nakatani Y, Münger K, Howley PM. Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding. Proceedings of the National Academy of Sciences of the United States of America. 102: 11486-91. PMID 16081543 DOI: 10.1073/Pnas.0505322102 |
0.468 |
|
| 2005 |
Huh KW, DeMasi J, Ogawa H, Nakatani Y, Howley PM, Münger K. Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600. Proceedings of the National Academy of Sciences of the United States of America. 102: 11492-7. PMID 16061792 DOI: 10.1073/Pnas.0505337102 |
0.488 |
|
| 2005 |
Bossis I, Roden RB, Gambhira R, Yang R, Tagaya M, Howley PM, Meneses PI. Interaction of tSNARE syntaxin 18 with the papillomavirus minor capsid protein mediates infection. Journal of Virology. 79: 6723-31. PMID 15890910 DOI: 10.1128/Jvi.79.11.6723-6731.2005 |
0.346 |
|
| 2004 |
Walters KJ, Goh AM, Wang Q, Wagner G, Howley PM. Ubiquitin family proteins and their relationship to the proteasome: a structural perspective. Biochimica Et Biophysica Acta. 1695: 73-87. PMID 15571810 DOI: 10.1016/J.Bbamcr.2004.10.005 |
0.35 |
|
| 2004 |
Cooper EM, Hudson AW, Amos J, Wagstaff J, Howley PM. Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. The Journal of Biological Chemistry. 279: 41208-17. PMID 15263005 DOI: 10.1074/Jbc.M401302200 |
0.359 |
|
| 2004 |
You J, Croyle JL, Nishimura A, Ozato K, Howley PM. Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell. 117: 349-60. PMID 15109495 DOI: 10.1016/S0092-8674(04)00402-7 |
0.457 |
|
| 2003 |
Wang Q, Goh AM, Howley PM, Walters KJ. Ubiquitin recognition by the DNA repair protein hHR23a. Biochemistry. 42: 13529-35. PMID 14621999 DOI: 10.1021/Bi035391J |
0.371 |
|
| 2003 |
Walters KJ, Lech PJ, Goh AM, Wang Q, Howley PM. DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a. Proceedings of the National Academy of Sciences of the United States of America. 100: 12694-9. PMID 14557549 DOI: 10.1073/Pnas.1634989100 |
0.364 |
|
| 2003 |
Kleijnen MF, Alarcon RM, Howley PM. The ubiquitin-associated domain of hPLIC-2 interacts with the proteasome. Molecular Biology of the Cell. 14: 3868-75. PMID 12972570 DOI: 10.1091/Mbc.E02-11-0766 |
0.783 |
|
| 2003 |
Wells SI, Aronow BJ, Wise TM, Williams SS, Couget JA, Howley PM. Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 7093-8. PMID 12756294 DOI: 10.1073/Pnas.1232309100 |
0.445 |
|
| 2002 |
Münger K, Howley PM. Human papillomavirus immortalization and transformation functions. Virus Research. 89: 213-28. PMID 12445661 DOI: 10.1016/S0168-1702(02)00190-9 |
0.444 |
|
| 2002 |
Karpova AY, Trost M, Murray JM, Cantley LC, Howley PM. Interferon regulatory factor-3 is an in vivo target of DNA-PK. Proceedings of the National Academy of Sciences of the United States of America. 99: 2818-23. PMID 11867762 DOI: 10.1073/Pnas.052713899 |
0.329 |
|
| 2002 |
Walters KJ, Kleijnen MF, Goh AM, Wagner G, Howley PM. Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a. Biochemistry. 41: 1767-77. PMID 11827521 DOI: 10.1021/Bi011892Y |
0.777 |
|
| 2002 |
Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE, Rubin DH. Fundamental Virology, 4th Edition; and Fields Virology, 4th Edition, Volumes I and II:Fundamental Virology, 4th Edition;Fields Virology, 4th Edition, Volumes I and II Clinical Infectious Diseases. 34: 1029-1030. DOI: 10.1086/339330 |
0.488 |
|
| 2000 |
Karpova AY, Howley PM, Ronco LV. Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene. Genes & Development. 14: 2813-8. PMID 11090129 DOI: 10.1101/Gad.813800 |
0.315 |
|
| 2000 |
Wells SI, Francis DA, Karpova AY, Dowhanick JJ, Benson JD, Howley PM. Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways. The Embo Journal. 19: 5762-71. PMID 11060027 DOI: 10.1093/Emboj/19.21.5762 |
0.47 |
|
| 2000 |
Zhou P, Bogacki R, McReynolds L, Howley PM. Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins. Molecular Cell. 6: 751-6. PMID 11030355 DOI: 10.1016/S1097-2765(00)00074-5 |
0.352 |
|
| 2000 |
Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM. The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome Molecular Cell. 6: 409-419. PMID 10983987 DOI: 10.1016/S1097-2765(00)00040-X |
0.787 |
|
| 2000 |
Kao WH, Beaudenon SL, Talis AL, Huibregtse JM, Howley PM. Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase Journal of Virology. 74: 6408-6417. PMID 10864652 DOI: 10.1128/Jvi.74.14.6408-6417.2000 |
0.816 |
|
| 2000 |
Nishimura A, Ono T, Ishimoto A, Dowhanick JJ, Frizzell MA, Howley PM, Sakai H. Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition. Journal of Virology. 74: 3752-60. PMID 10729150 DOI: 10.1128/Jvi.74.8.3752-3760.2000 |
0.452 |
|
| 2000 |
Francis DA, Schmid SI, Howley PM. Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells. Journal of Virology. 74: 2679-86. PMID 10684283 DOI: 10.1128/Jvi.74.6.2679-2686.2000 |
0.459 |
|
| 1999 |
Huang L, Kinnucan E, Wang G, Beaudenon S, Howley PM, Huibregtse JM, Pavletich NP. Structure of an E6AP-UbcH7 complex: Insights into ubiquitination by the E2-E3 enzyme cascade Science. 286: 1321-1326. PMID 10558980 DOI: 10.1126/Science.286.5443.1321 |
0.673 |
|
| 1999 |
Kumar S, Talis AL, Howley PM. Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination. The Journal of Biological Chemistry. 274: 18785-92. PMID 10373495 DOI: 10.1074/Jbc.274.26.18785 |
0.465 |
|
| 1999 |
Unger T, Sionov RV, Moallem E, Yee CL, Howley PM, Oren M, Haupt Y. Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. Oncogene. 18: 3205-12. PMID 10359526 DOI: 10.1038/Sj.Onc.1202656 |
0.341 |
|
| 1998 |
Zhou P, Howley PM. Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Molecular Cell. 2: 571-80. PMID 9844630 DOI: 10.1016/S1097-2765(00)80156-2 |
0.316 |
|
| 1998 |
Benson JD, Benson M, Howley PM, Struhl K. Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes Embo Journal. 17: 6714-6722. PMID 9822614 DOI: 10.1093/Emboj/17.22.6714 |
0.317 |
|
| 1998 |
Kasukawa H, Howley PM, Benson JD. A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro. Journal of Virology. 72: 8166-73. PMID 9733858 DOI: 10.1128/Jvi.72.10.8166-8173.1998 |
0.431 |
|
| 1998 |
Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, Maniatis T. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Molecular Cell. 1: 507-18. PMID 9660935 DOI: 10.1016/S1097-2765(00)80051-9 |
0.349 |
|
| 1998 |
Ronco LV, Karpova AY, Vidal M, Howley PM. Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes & Development. 12: 2061-72. PMID 9649509 DOI: 10.1101/Gad.12.13.2061 |
0.445 |
|
| 1998 |
Talis AL, Huibregtse JM, Howley PM. The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells Journal of Biological Chemistry. 273: 6439-6445. PMID 9497376 DOI: 10.1074/Jbc.273.11.6439 |
0.701 |
|
| 1998 |
Tong X, Boll W, Kirchhausen T, Howley PM. Interaction of the bovine papillomavirus E6 protein with the clathrin adaptor complex AP-1 Journal of Virology. 72: 476-482. PMID 9420248 DOI: 10.1128/Jvi.72.1.476-482.1998 |
0.394 |
|
| 1998 |
Tong X, Salgia R, Li JL, Griffin JD, Howley PM. The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase. The Journal of Biological Chemistry. 272: 33373-6. PMID 9407131 DOI: 10.1074/Jbc.272.52.33373 |
0.41 |
|
| 1997 |
Benson JD, Lawande R, Howley PM. Conserved interaction of the papillomavirus E2 transcriptional activator proteins with human and yeast TFIIB proteins. Journal of Virology. 71: 8041-7. PMID 9311902 DOI: 10.1128/Jvi.71.10.8041-8047.1997 |
0.464 |
|
| 1997 |
Yasugi T, Vidal M, Sakai H, Howley PM, Benson JD. Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins. Journal of Virology. 71: 5942-51. PMID 9223484 DOI: 10.1128/Jvi.71.8.5942-5951.1997 |
0.475 |
|
| 1997 |
Kumar S, Kao WH, Howley PM. Physical interaction between specific E2 and hect E3 enzymes determines functional cooperativity Journal of Biological Chemistry. 272: 13548-13554. PMID 9153201 DOI: 10.1074/Jbc.272.21.13548 |
0.771 |
|
| 1997 |
Yamamoto Y, Huibregtse JM, Howley PM. The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing Genomics. 41: 263-266. PMID 9143503 DOI: 10.1006/Geno.1997.4617 |
0.695 |
|
| 1997 |
Tong X, Howley PM. The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 94: 4412-7. PMID 9114003 DOI: 10.1073/Pnas.94.9.4412 |
0.454 |
|
| 1997 |
Yasugi T, Benson JD, Sakai H, Vidal M, Howley PM. Mapping and characterization of the interaction domains of human papillomavirus type 16 E1 and E2 proteins. Journal of Virology. 71: 891-9. PMID 8995605 DOI: 10.1128/Jvi.71.2.891-899.1997 |
0.466 |
|
| 1996 |
Yasugi T, Howley PM. Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9. Nucleic Acids Research. 24: 2005-10. PMID 8668529 DOI: 10.1093/Nar/24.11.2005 |
0.405 |
|
| 1996 |
Khleif SN, DeGregori J, Yee CL, Otterson GA, Kaye FJ, Nevins JR, Howley PM. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proceedings of the National Academy of Sciences of the United States of America. 93: 4350-4. PMID 8633069 DOI: 10.1073/Pnas.93.9.4350 |
0.343 |
|
| 1996 |
Sakai H, Yasugi T, Benson JD, Dowhanick JJ, Howley PM. Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions. Journal of Virology. 70: 1602-11. PMID 8627680 DOI: 10.1128/Jvi.70.3.1602-1611.1996 |
0.48 |
|
| 1996 |
Arbeit JM, Howley PM, Hanahan D. Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 93: 2930-2935. PMID 8610145 DOI: 10.1073/Pnas.93.7.2930 |
0.335 |
|
| 1995 |
Vande Pol SB, Howley PM. Negative regulation of the bovine papillomavirus E5, E6, and E7 oncogenes by the viral E1 and E2 genes. Journal of Virology. 69: 395-402. PMID 7983735 DOI: 10.1128/Jvi.69.1.395-402.1995 |
0.421 |
|
| 1995 |
Benson JD, Howley PM. Amino-terminal domains of the bovine papillomavirus type 1 E1 and E2 proteins participate in complex formation. Journal of Virology. 69: 4364-72. PMID 7769698 DOI: 10.1128/Jvi.69.7.4364-4372.1995 |
0.451 |
|
| 1995 |
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase Proceedings of the National Academy of Sciences of the United States of America. 92: 5249. PMID 7761480 DOI: 10.1073/Pnas.92.7.2563 |
0.695 |
|
| 1995 |
Dowhanick JJ, McBride AA, Howley PM. Suppression of cellular proliferation by the papillomavirus E2 protein Journal of Virology. 69: 7791-7799. PMID 7494290 DOI: 10.1128/Jvi.69.12.7791-7799.1995 |
0.481 |
|
| 1995 |
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. Correction: A Family of Proteins Structurally and Functionally Related to the E6-AP Ubiquitin-Protein Ligase Proceedings of the National Academy of Sciences of the United States of America. 92: 5249-5249. DOI: 10.1073/Pnas.92.11.5249-A |
0.655 |
|
| 1994 |
Scheffner M, Romanczuk H, Munger K, Huibregtse JM, Mietz JA, Howley PM. Functions of human papillomavirus proteins Current Topics in Microbiology and Immunology. 186: 83-99. PMID 8205847 DOI: 10.1007/978-3-642-78487-3_5 |
0.637 |
|
| 1994 |
Scheffner M, Huibregtse JM, Howley PM. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53 Proceedings of the National Academy of Sciences of the United States of America. 91: 8797-8801. PMID 8090726 DOI: 10.1073/Pnas.91.19.8797 |
0.699 |
|
| 1994 |
Huibregtse JM, Scheffner M, Howley PM. E6-AP directs the HPV E6-dependent inactivation of p53 and is representative of a family of structurally and functionally related proteins Cold Spring Harbor Symposia On Quantitative Biology. 59: 237-245. PMID 7587075 DOI: 10.1101/Sqb.1994.059.01.028 |
0.689 |
|
| 1994 |
Arbeit JM, Münger K, Howley PM, Hanahan D. Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice Journal of Virology. 68: 4358-4368. PMID 7515971 DOI: 10.1128/Jvi.68.7.4358-4368.1994 |
0.394 |
|
| 1993 |
Huibregtse JM, Scheffner M, Howley PM. Localization of the E6-AP Regions That Direct Human Papillomavirus E6 Binding, Association with p53, and Ubiquitination of Associated Proteins Molecular and Cellular Biology. 13: 4918-4927. PMID 8393140 DOI: 10.1128/Mcb.13.8.4918 |
0.693 |
|
| 1993 |
Huibregtse JM, Scheffner M, Howley PM. Cloning and Expression of the cDNA for E6-AP, a Protein That Mediates the Interaction of the Human Papillomavirus E6 Oncoprotein with p53 Molecular and Cellular Biology. 13: 775-784. PMID 8380895 DOI: 10.1128/Mcb.13.2.775 |
0.711 |
|
| 1993 |
Unger T, Mietz JA, Scheffner M, Yee CL, Howley PM. Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression. Molecular and Cellular Biology. 13: 5186-94. PMID 8355677 DOI: 10.1128/Mcb.13.9.5186 |
0.364 |
|
| 1993 |
Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 Cell. 75: 495-505. PMID 8221889 DOI: 10.1016/0092-8674(93)90384-3 |
0.707 |
|
| 1992 |
Del Vecchio AM, Romanczuk H, Howley PM, Baker CC. Transient replication of human papillomavirus DNAs. Journal of Virology. 66: 5949-58. PMID 1326651 DOI: 10.1128/Jvi.66.10.5949-5958.1992 |
0.417 |
|
| 1992 |
McBride AA, Klausner RD, Howley PM. Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro Proceedings of the National Academy of Sciences of the United States of America. 89: 7531-7535. PMID 1323841 DOI: 10.1073/Pnas.89.16.7531 |
0.443 |
|
| 1992 |
Scheffner M, Takahashi T, Huibregtse JM, Minna JD, Howley PM. Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins Journal of Virology. 66: 5100-5105. PMID 1321290 DOI: 10.1128/Jvi.66.8.5100-5105.1992 |
0.698 |
|
| 1992 |
Scheffner M, Münger K, Huibregtse JM, Howley PM. Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins Embo Journal. 11: 2425-2431. PMID 1321031 DOI: 10.1002/J.1460-2075.1992.Tb05307.X |
0.703 |
|
| 1992 |
Chellappan S, Kraus VB, Kroger B, Munger K, Howley PM, Phelps WC, Nevins JR. Adeno virus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product Proceedings of the National Academy of Sciences of the United States of America. 89: 4549-4553. PMID 1316611 DOI: 10.1073/Pnas.89.10.4549 |
0.462 |
|
| 1992 |
Heck DV, Yee CL, Howley PM, Münger K. Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proceedings of the National Academy of Sciences of the United States of America. 89: 4442-6. PMID 1316608 DOI: 10.1073/Pnas.89.10.4442 |
0.425 |
|
| 1992 |
Thierry F, Spyrou G, Yaniv M, Howley P. Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes. Journal of Virology. 66: 3740-3748. PMID 1316480 DOI: 10.1128/Jvi.66.6.3740-3748.1992 |
0.384 |
|
| 1992 |
Romanczuk H, Howley PM. Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proceedings of the National Academy of Sciences of the United States of America. 89: 3159-63. PMID 1313584 DOI: 10.1073/Pnas.89.7.3159 |
0.466 |
|
| 1992 |
Phelps WC, Münger K, Yee CL, Barnes JA, Howley PM. Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein. Journal of Virology. 66: 2418-27. PMID 1312637 DOI: 10.1128/Jvi.66.4.2418-2427.1992 |
0.435 |
|
| 1992 |
Vande Pol SB, Howley PM. The bovine papillomavirus constitutive enhancer is essential for viral transformation, DNA replication, and the maintenance of latency. Journal of Virology. 66: 2346-58. PMID 1312634 DOI: 10.1128/Jvi.66.4.2346-2358.1992 |
0.406 |
|
| 1992 |
Mietz J, Unger T, Huibregtse J, Howley P. The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. The Embo Journal. 11: 5013-5020. DOI: 10.1002/J.1460-2075.1992.Tb05608.X |
0.692 |
|
| 1992 |
Scheffner M, Münger K, Huibregtse J, Howley P. Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins. The Embo Journal. 11: 2425-2431. DOI: 10.1002/j.1460-2075.1992.tb05307.x |
0.661 |
|
| 1991 |
Romanczuk H, Villa LL, Schlegel R, Howley PM. The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18. Journal of Virology. 65: 2739-44. PMID 1850048 DOI: 10.1128/Jvi.65.5.2739-2744.1991 |
0.44 |
|
| 1991 |
Spalholz BA, Vande Pol SB, Howley PM. Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter. Journal of Virology. 65: 743-53. PMID 1846195 DOI: 10.1128/Jvi.65.2.743-753.1991 |
0.427 |
|
| 1991 |
Phelps WC, Bagchi S, Barnes JA, Raychaudhuri P, Kraus V, Münger K, Howley PM, Nevins JR. Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism. Journal of Virology. 65: 6922-30. PMID 1834862 DOI: 10.1128/Jvi.65.12.6922-6930.1991 |
0.457 |
|
| 1991 |
Howley PM, Scheffner M, Huibregtse J, Munger K. Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes Cold Spring Harbor Symposia On Quantitative Biology. 56: 149-155. PMID 1668080 DOI: 10.1101/Sqb.1991.056.01.019 |
0.614 |
|
| 1991 |
Huibregtse JM, Scheffner M, Howley PM. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18 Embo Journal. 10: 4129-4135. PMID 1661671 DOI: 10.1002/J.1460-2075.1991.Tb04990.X |
0.706 |
|
| 1991 |
McBride AA, Howley PM. Bovine papillomavirus with a mutation in the E2 serine 301 phosphorylation site replicates at a high copy number Journal of Virology. 65: 6528-6534. PMID 1658358 DOI: 10.1128/Jvi.65.12.6528-6534.1991 |
0.482 |
|
| 1991 |
Dostatni N, Lambert PF, Sousa R, Ham J, Howley PM, Yaniv M. The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex Genes and Development. 5: 1657-1671. PMID 1653173 DOI: 10.1101/Gad.5.9.1657 |
0.621 |
|
| 1991 |
Scheffner M, Munger K, Byrne JC, Howley PM. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines Proceedings of the National Academy of Sciences of the United States of America. 88: 5523-5527. PMID 1648218 DOI: 10.1073/Pnas.88.13.5523 |
0.409 |
|
| 1991 |
Münger K, Yee CL, Phelps WC, Pietenpol JA, Moses HL, Howley PM. Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences. Journal of Virology. 65: 3943-8. PMID 1645802 DOI: 10.1128/Jvi.65.7.3943-3948.1991 |
0.443 |
|
| 1991 |
Schiffman MH, Bauer HM, Lorincz AT, Manos MM, Byrne JC, Glass AG, Cadell DM, Howley PM. Comparison of Southern blot hybridization and polymerase chain reaction methods for the detection of human papillomavirus DNA Journal of Clinical Microbiology. 29: 573-577. PMID 1645370 DOI: 10.1128/Jcm.29.3.573-577.1991 |
0.335 |
|
| 1991 |
Huibregtse J, Scheffner M, Howley P. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. The Embo Journal. 10: 4129-4135. DOI: 10.1002/j.1460-2075.1991.tb04990.x |
0.666 |
|
| 1990 |
Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 Cell. 63: 1129-1136. PMID 2175676 DOI: 10.1016/0092-8674(90)90409-8 |
0.719 |
|
| 1990 |
Vande Pol SB, Howley PM. A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor. Journal of Virology. 64: 5420-9. PMID 2170679 DOI: 10.1128/Jvi.64.11.5420-5429.1990 |
0.398 |
|
| 1990 |
Romanczuk H, Thierry F, Howley PM. Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. Journal of Virology. 64: 2849-59. PMID 2159546 DOI: 10.1128/Jvi.64.6.2849-2859.1990 |
0.442 |
|
| 1990 |
Werness BA, Levine AJ, Howley PM. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (New York, N.Y.). 248: 76-9. PMID 2157286 DOI: 10.1126/Science.2157286 |
0.489 |
|
| 1990 |
Lambert PF, Monk BC, Howley PM. Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants Journal of Virology. 64: 950-956. PMID 2153256 DOI: 10.1128/Jvi.64.2.950-956.1990 |
0.61 |
|
| 1990 |
Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM, Pittelkow MR, Münger K, Howley PM, Moses HL. TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell. 61: 777-85. PMID 2140528 DOI: 10.1016/0092-8674(90)90188-K |
0.346 |
|
| 1989 |
Münger K, Werness BA, Dyson N, Phelps WC, Harlow E, Howley PM. Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. The Embo Journal. 8: 4099-105. PMID 2556261 DOI: 10.1002/J.1460-2075.1989.Tb08594.X |
0.441 |
|
| 1989 |
McBride AA, Bolen JB, Howley PM. Phosphorylation sites of the E2 transcriptional regulatory proteins of bovine papillomavirus type 1 Journal of Virology. 63: 5076-5085. PMID 2555544 DOI: 10.1128/Jvi.63.12.5076-5085.1989 |
0.452 |
|
| 1989 |
Phelps WC, Yee CL, Münger K, Howley PM. Functional and sequence similarities between HPV16 E7 and adenovirus E1A. Current Topics in Microbiology and Immunology. 144: 153-66. PMID 2551580 DOI: 10.1007/978-3-642-74578-2_19 |
0.347 |
|
| 1989 |
Lambert PF, Hubbert NL, Howley PM, Schiller JT. Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells Journal of Virology. 63: 3151-3154. PMID 2542621 DOI: 10.1128/Jvi.63.7.3151-3154.1989 |
0.616 |
|
| 1989 |
Lambert PF, Dostatni N, McBride AA, Yaniv M, Howley PM, Arcangioli B. Functional analysis of the papilloma virus E2 trans-activator in Saccharomyces cerevisiae Genes &Amp; Development. 3: 38-48. PMID 2540059 DOI: 10.1101/Gad.3.1.38 |
0.602 |
|
| 1989 |
Dyson N, Howley PM, Münger K, Harlow E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (New York, N.Y.). 243: 934-7. PMID 2537532 DOI: 10.1126/Science.2537532 |
0.425 |
|
| 1989 |
McBride AA, Byrne LC, Howley PM. E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: Transactivation is mediated by the conserved amino-terminal domain Proceedings of the National Academy of Sciences of the United States of America. 86: 510-514. PMID 2536165 DOI: 10.1073/Pnas.86.2.510 |
0.469 |
|
| 1989 |
Munger K, Phelps WC, Bubb V, Howley PM. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes Journal of Virology. 63: 4417-4421. PMID 2476573 DOI: 10.1128/Jvi.63.10.4417-4421.1989 |
0.416 |
|
| 1988 |
Sarver N, Gruss P, Law MF, Khoury G, Howley PM. Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Molecular and Cellular Biology. 1: 486-96. PMID 6100967 DOI: 10.1128/Mcb.1.6.486 |
0.628 |
|
| 1988 |
Lambert PF, Baker CC, Howley PM. The genetics of bovine papillomavirus type 1 Annual Review of Genetics. 22: 235-258. PMID 2853608 DOI: 10.1146/Annurev.Ge.22.120188.001315 |
0.486 |
|
| 1988 |
Lambert PF, Howley PM. Bovine papillomavirus in type 1 E1 replication-defective mutants are altered in their transcriptional regulation Journal of Virology. 62: 4009-4015. PMID 2845119 DOI: 10.1128/Jvi.62.11.4009-4015.1988 |
0.618 |
|
| 1988 |
Spalholz BA, Byrne JC, Howley PM. Evidence for cooperativity between E2 binding sites in E2 trans-regulation of bovine papillomavirus type 1. Journal of Virology. 62: 3143-50. PMID 2841467 DOI: 10.1128/Jvi.62.9.3143-3150.1988 |
0.402 |
|
| 1988 |
Phelps WC, Yee CL, Münger K, Howley PM. The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell. 53: 539-47. PMID 2836062 DOI: 10.1016/0092-8674(88)90570-3 |
0.455 |
|
| 1988 |
Hermonat PL, Spalholz BA, Howley PM. The bovine papillomavirus P2443 promoter is E2 trans-responsive: evidence for E2 autoregulation. The Embo Journal. 7: 2815-2822. DOI: 10.1002/J.1460-2075.1988.Tb03137.X |
0.437 |
|
| 1988 |
McBride AA, Schlegel R, Howley PM. The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity. The Embo Journal. 7: 533-539. DOI: 10.1002/J.1460-2075.1988.Tb02842.X |
0.461 |
|
| 1987 |
Lambert PF, Spalholz BA, Howley PM. A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator Cell. 50: 69-78. PMID 3036366 DOI: 10.1016/0092-8674(87)90663-5 |
0.592 |
|
| 1987 |
Spalholz BA, Lambert PF, Yee CL, Howley PM. Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. Journal of Virology. 61: 2128-37. PMID 3035214 DOI: 10.1128/Jvi.61.7.2128-2137.1987 |
0.6 |
|
| 1987 |
Phelps WC, Howley PM. Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. Journal of Virology. 61: 1630-8. PMID 3033289 DOI: 10.1128/Jvi.61.5.1630-1638.1987 |
0.421 |
|
| 1987 |
Baker CC, Phelps WC, Lindgren V, Braun MJ, Gonda MA, Howley PM. Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. Journal of Virology. 61: 962-71. PMID 3029430 DOI: 10.1128/Jvi.61.4.962-971.1987 |
0.439 |
|
| 1987 |
Hermonat PL, Howley PM. Mutational analysis of the 3' open reading frames and the splice junction at nucleotide 3225 of bovine papillomavirus type 1. Journal of Virology. 61: 3889-95. PMID 2824822 DOI: 10.1128/Jvi.61.12.3889-3895.1987 |
0.421 |
|
| 1987 |
Byrne JC, Tsao MS, Fraser RS, Howley PM. Human papillomavirus-11 DNA in a patient with chronic laryngotracheobronchial papillomatosis and metastatic squamous-cell carcinoma of the lung. The New England Journal of Medicine. 317: 873-8. PMID 2442608 DOI: 10.1056/Nejm198710013171406 |
0.352 |
|
| 1987 |
Baker C, Howley P. Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues. The Embo Journal. 6: 1027-1035. DOI: 10.1002/J.1460-2075.1987.Tb04855.X |
0.337 |
|
| 1986 |
Rabson MS, Yee C, Yang YC, Howley PM. Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions. Journal of Virology. 60: 626-34. PMID 3021996 DOI: 10.1128/Jvi.60.2.626-634.1986 |
0.424 |
|
| 1986 |
Sarver N, Muschel R, Byrne JC, Khoury G, Howley PM. Enhancer-dependent expression of the rat preproinsulin gene in bovine papillomavirus type 1 vectors. Molecular and Cellular Biology. 5: 3507-16. PMID 3018523 DOI: 10.1128/mcb.5.12.3507-3516.1985 |
0.612 |
|
| 1986 |
Eiden M, Newman M, Fisher AG, Mann DL, Howley PM, Reitz MS. Type 1 human T-cell leukemia virus small envelope protein expressed in mouse cells by using a bovine papilloma virus-derived shuttle vector. Molecular and Cellular Biology. 5: 3320-4. PMID 3018517 DOI: 10.1128/Mcb.5.11.3320 |
0.371 |
|
| 1986 |
Levens D, Howley PM. Novel method for identifying sequence-specific DNA-binding proteins. Molecular and Cellular Biology. 5: 2307-15. PMID 3016526 DOI: 10.1128/Mcb.5.9.2307 |
0.361 |
|
| 1986 |
Yang YC, Spalholz BA, Rabson MS, Howley PM. Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1. Nature. 318: 575-7. PMID 2999614 DOI: 10.1038/318575A0 |
0.437 |
|
| 1986 |
Gendelman HE, Phelps W, Feigenbaum L, Ostrove JM, Adachi A, Howley PM, Khoury G, Ginsberg HS, Martin MA. Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proceedings of the National Academy of Sciences of the United States of America. 83: 9759-63. PMID 2432602 DOI: 10.1073/Pnas.83.24.9759 |
0.691 |
|
| 1986 |
Small JA, Khoury G, Jay G, Howley PM, Scangos GA. Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 83: 8288-92. PMID 2430282 DOI: 10.1073/Pnas.83.21.8288 |
0.58 |
|
| 1985 |
Howley PM, Schenborn ET, Lund E, Byrne JC, Dahlberg JE. The bovine papillomavirus distal "enhancer" is not cis essential for transformation or for plasmid maintenance. Molecular and Cellular Biology. 5: 3310-5. PMID 3018516 DOI: 10.1128/Mcb.5.11.3310 |
0.362 |
|
| 1985 |
Spalholz BA, Yang YC, Howley PM. Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product. Cell. 42: 183-91. PMID 2990724 DOI: 10.1016/S0092-8674(85)80114-8 |
0.388 |
|
| 1985 |
Yang YC, Okayama H, Howley PM. Bovine papillomavirus contains multiple transforming genes Proceedings of the National Academy of Sciences of the United States of America. 82: 1030-1034. PMID 2983327 DOI: 10.1073/Pnas.82.4.1030 |
0.389 |
|
| 1984 |
Law MF, Byrne JC, Howley PM. A stable bovine papillomavirus hybrid plasmid that expresses a dominant selective trait. Molecular and Cellular Biology. 3: 2110-5. PMID 6318082 DOI: 10.1128/Mcb.3.11.2110 |
0.301 |
|
| 1984 |
Sarver N, Rabson MS, Yang YC, Byrne JC, Howley PM. Localization and analysis of bovine papillomavirus type 1 transforming functions. Journal of Virology. 52: 377-88. PMID 6092667 DOI: 10.1128/Jvi.52.2.377-388.1984 |
0.401 |
|
| 1983 |
Howley PM, Sarver N, Law MF. Eukaryotic cloning vectors derived from bovine papillomavirus DNA. Methods in Enzymology. 101: 387-402. PMID 6310337 DOI: 10.1016/0076-6879(83)01029-0 |
0.329 |
|
| 1983 |
Danos O, Engel LW, Chen EY, Yaniv M, Howley PM. Comparative analysis of the human type 1a and bovine type 1 papillomavirus genomes Journal of Virology. 46: 557-566. PMID 6302319 DOI: 10.1128/Jvi.46.2.557-566.1983 |
0.365 |
|
| 1983 |
Mitrani-Rosenbaum S, Maroteaux L, Mory Y, Revel M, Howley PM. Inducible expression of the human interferon beta 1 gene linked to a bovine papilloma virus DNA vector and maintained extrachromosomally in mouse cells. Molecular and Cellular Biology. 3: 233-40. PMID 6300659 DOI: 10.1128/Mcb.3.2.233 |
0.336 |
|
| 1983 |
Sarver N, Byrne JC, Howley PM. Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria. Proceedings of the National Academy of Sciences of the United States of America. 79: 7147-51. PMID 6296820 DOI: 10.1073/Pnas.79.23.7147 |
0.325 |
|
| 1983 |
Sarver N, Mitrani-Rosenbaum S, Law M-, McAllister WT, Byrne JC, Howley PM. Bovine Papillomavirus Shuttle Vectors Genetic Engineering. 5: 173-190. DOI: 10.1007/978-1-4684-4556-5_9 |
0.312 |
|
| 1982 |
Heilman CA, Engel L, Lowy DR, Howley PM. Virus-specific transcription in bovine papillomavirus-transformed mouse cells. Virology. 119: 22-34. PMID 6280384 DOI: 10.1016/0042-6822(82)90061-7 |
0.301 |
|
| 1982 |
Turek LP, Byrne JC, Lowy DR, Dvoretzky I, Friedman RM, Howley PM. Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 7914-8. PMID 6185955 DOI: 10.1073/Pnas.79.24.7914 |
0.325 |
|
| 1982 |
Chen EY, Howley PM, Levinson AD, Seeburg PH. The primary structure and genetic organization of the bovine papillomavirus type 1 genome Nature. 299: 529-534. DOI: 10.1038/299529A0 |
0.363 |
|
| 1981 |
Law MF, Lowy DR, Dvoretzky I, Howley PM. Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 78: 2727-31. PMID 6265905 DOI: 10.1073/Pnas.78.5.2727 |
0.35 |
|
| 1981 |
Rentier-Delrue F, Lubiniecki A, Howley PM. Analysis of JC virus DNA purified directly from human progressive multifocal leukoencephalopathy brains. Journal of Virology. 38: 761-9. PMID 6264142 DOI: 10.1128/Jvi.38.2.761-769.1981 |
0.333 |
|
| 1981 |
Goldman ND, Howley P, Khoury G. Functional interaction between the early viral proteins of simian virus 40 and adenovirus. Virology. 109: 303-313. PMID 6259813 DOI: 10.1016/0042-6822(81)90501-8 |
0.627 |
|
| 1980 |
Howley PM, Rentier-Delrue F, Heilman CA, Law MF, Chowdhury K, Israel MA, Takemoto KK. Cloned human polyomavirus JC DNA can transform human amnion cells Journal of Virology. 36: 878-882. PMID 6257931 DOI: 10.1128/Jvi.36.3.878-882.1980 |
0.354 |
|
| 1980 |
Heilman CA, Law MF, Israel MA, Howley PM. Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences Journal of Virology. 36: 395-407. PMID 6253665 DOI: 10.1128/Jvi.36.2.395-407.1980 |
0.38 |
|
| 1980 |
Lowy DR, Dvoretzky I, Shober R, Law MF, Engel L, Howley PM. In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature. 287: 72-4. PMID 6251381 DOI: 10.1038/287072A0 |
0.335 |
|
| 1980 |
Howley PM. DNA sequence of human papovavirus BK. Nature. 284: 124-5. PMID 6244496 DOI: 10.1038/284124A0 |
0.303 |
|
| 1979 |
Takemoto KK, Howley PM, Miyamura T. JC human papovavirus replication in human amnion cells. Journal of Virology. 30: 384-9. PMID 480459 DOI: 10.1128/Jvi.30.1.384-389.1979 |
0.336 |
|
| 1979 |
Law MF, Lancaster WD, Howley PM. Conserved polynucleotide sequences among the genomes of papillomaviruses Journal of Virology. 32: 199-207. PMID 232171 DOI: 10.1128/Jvi.32.1.199-207.1979 |
0.394 |
|
| 1979 |
Law MF, Martin JD, Takemoto KK, Howley PM. The colinear alignment of the genomes of papovaviruses JC, BK, and SV40. Virology. 96: 576-87. PMID 223318 DOI: 10.1016/0042-6822(79)90113-2 |
0.315 |
|
| 1979 |
Israel MA, Martin MA, Takemoto KK, Howley PM, Aaronson SA, Solomon D, Khoury G. Evaluation of normal and neoplastic human tissue for BK virus. Virology. 90: 187-96. PMID 214941 DOI: 10.1016/0042-6822(78)90302-1 |
0.694 |
|
| 1978 |
Bond SB, Howley PM, Takemoto KK. Characterization of K virus and its comparison with polyoma virus. Journal of Virology. 28: 337-43. PMID 81318 DOI: 10.1128/Jvi.28.1.337-343.1978 |
0.314 |
|
| 1977 |
Howley PM, Martin MA. Uniform representation of the human papovavirus BK genome in transformed hamster cells Journal of Virology. 23: 205-208. PMID 196104 DOI: 10.1128/Jvi.23.1.205-208.1977 |
0.581 |
|
| 1977 |
Davoli D, Ganem D, Nussbaum AL, Fareed G, Howley PM, Khoury G, Martin MA. Genome Structures of reiteration mutants of simian virus 40. Virology. 77: 110-24. PMID 190779 DOI: 10.1016/0042-6822(77)90411-1 |
0.7 |
|
| 1976 |
Howley PM, Khoury G, Takemoto KK, Martin MA. Polynucleotide sequences common to the genomes of simian virus 40 and the human papovaviruses JC and BK. Virology. 73: 303-7. PMID 183358 DOI: 10.1016/0042-6822(76)90084-2 |
0.697 |
|
| 1976 |
Martin MA, Howley PM, Byrne JC, Garon CF. Characterization of supercoiled oligomeric SV40 DNA molecules in productively infected cells. Virology. 71: 28-40. PMID 179203 DOI: 10.1016/0042-6822(76)90091-X |
0.556 |
|
| 1976 |
Khoury G, Carter BJ, Ferdinand FJ, Howley PM, Brown M, Martin MA. Genome localization of simian virus 40 RNA species. Journal of Virology. 17: 832-40. PMID 176448 DOI: 10.1128/Jvi.17.3.832-840.1976 |
0.689 |
|
| 1975 |
Khoury G, Howley PM, Garon C, Mullarkey MF, Takemoto KK, Martin MA. Homology and relationship between the genomes of papovaviruses, BK virus and simian virus 40. Proceedings of the National Academy of Sciences of the United States of America. 72: 2563-7. PMID 170606 DOI: 10.1073/Pnas.72.7.2563 |
0.684 |
|
| 1975 |
Howley PM, Khoury G, Byrne JC, Takemoto KK, Martin MA. Physical map of the BK virus genome. Journal of Virology. 16: 959-73. PMID 170425 DOI: 10.1128/Jvi.16.4.959-973.1975 |
0.694 |
|
| 1975 |
Khoury G, Howley P, Nathans D, Martin M. Posttranscriptional selection of simian virus 40-specific RNA. Journal of Virology. 15: 433-7. PMID 163366 DOI: 10.1128/Jvi.15.2.433-437.1975 |
0.708 |
|
| 1975 |
Howley PM, Mullarkey MF, Takemoto KK, Martin MA. Characterization of human papovavirus BK DNA. Journal of Virology. 15: 173-81. PMID 163342 DOI: 10.1128/Jvi.15.1.173-181.1975 |
0.565 |
|
| 1974 |
Khoury G, Howley P, Brown M, Martin M. The Detection and Quantitation of SV40 Nucleic Acid Sequences Using Single-stranded SV40 DNA Probes Cold Spring Harbor Symposia On Quantitative Biology. 39: 147-152. PMID 169053 DOI: 10.1101/Sqb.1974.039.01.020 |
0.675 |
|
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