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Danwei Huangfu - Publications

Affiliations: 
Developmental Biology Sloan-Kettering Institute, New York, NY, United States 
Area:
Stem cells, development, regeneration
Website:
http://www.mskcc.org/research/lab/danwei-huangfu
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rosen BP, Li QV, Cho HS, Liu D, Yang D, Graff S, Yan J, Luo R, Verma N, Damodaran JR, Kale HT, Kaplan SJ, Beer MA, Sidoli S, Huangfu D. Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness. Nature Communications. 15: 8966. PMID 39419994 DOI: 10.1038/s41467-024-53284-4  0.325
2023 Rosen BP, Li QV, Cho H, Liu D, Yang D, Graff S, Yan J, Luo R, Verma N, Damodaran JR, Beer MA, Sidoli S, Huangfu D. Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal. Biorxiv : the Preprint Server For Biology. PMID 37205540 DOI: 10.1101/2023.05.03.539283  0.312
2022 Chen T, Alcorn H, Devbhandari S, Remus D, Lacy E, Huangfu D, Anderson KV. A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation. Biology Open. 11. PMID 35876795 DOI: 10.1242/bio.059307  0.607
2021 Vanoli F, Meskauskaite B, Herviou L, Mallen W, Sung YS, Fujisawa Y, Zhang L, Simon S, Huangfu D, Jasin M, Antonescu CR. Generation of human embryonic stem cell models to exploit the EWSR1-CREB fusion promiscuity as a common pathway of transformation in human tumors. Oncogene. PMID 34193943 DOI: 10.1038/s41388-021-01843-0  0.35
2021 Huangfu D, García-García MJ, Eggenschwiler J. Kathryn Anderson (1952-2020). Developmental Cell. 56: 257-259. PMID 33561421 DOI: 10.1016/j.devcel.2021.01.009  0.616
2020 Beer MA, Shigaki D, Huangfu D. Enhancer Predictions and Genome-Wide Regulatory Circuits. Annual Review of Genomics and Human Genetics. PMID 32443951 DOI: 10.1146/Annurev-Genom-121719-010946  0.333
2019 Vardhana SA, Arnold PK, Rosen BP, Chen Y, Carey BW, Huangfu D, Fontaine CC, Thompson CB, Finley LWS. Glutamine independence is a selectable feature of pluripotent stem cells. Nature Metabolism. 1: 676-687. PMID 31511848 DOI: 10.1038/s42255-019-0082-3  0.318
2019 Li QV, Rosen BP, Huangfu D. Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1464. PMID 31407519 DOI: 10.1002/Wsbm.1464  0.412
2019 Lee K, Cho H, Rickert RW, Li QV, Pulecio J, Leslie CS, Huangfu D. FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation. Cell Reports. 28: 382-393.e7. PMID 31291575 DOI: 10.1016/J.Celrep.2019.06.034  0.392
2019 Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh CL, Yang D, Crespo M, Shukla A, Xiang Q, Dündar F, Zumbo P, ... ... Huangfu D, et al. Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Nature Genetics. PMID 31110351 DOI: 10.1038/S41588-019-0408-9  0.432
2018 Amin S, Cook B, Zhou T, Ghazizadeh Z, Lis R, Zhang T, Khalaj M, Crespo M, Perera M, Xiang JZ, Zhu Z, Tomishima M, Liu C, Naji A, Evans T, ... Huangfu D, et al. Discovery of a drug candidate for GLIS3-associated diabetes. Nature Communications. 9: 2681. PMID 29992946 DOI: 10.1038/S41467-018-04918-X  0.373
2018 Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, et al. Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells. Transplantation. PMID 29781950 DOI: 10.1097/Tp.0000000000002217  0.684
2017 Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang CJ, Papapetrou EP, He C, Elemento O, Huangfu D. Author Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells. Nature Genetics. PMID 29255265 DOI: 10.1038/S41588-017-0025-4  0.344
2017 Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang CJ, Papapetrou EP, He C, Elemento O, Huangfu D. TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells. Nature Genetics. PMID 29203910 DOI: 10.1038/S41588-017-0002-Y  0.384
2017 Pulecio J, Verma N, Mejía-Ramírez E, Huangfu D, Raya A. CRISPR/Cas9-Based Engineering of the Epigenome. Cell Stem Cell. 21: 431-447. PMID 28985525 DOI: 10.1016/J.Stem.2017.09.006  0.371
2017 Shi ZD, Soh CL, Zhu Z, Huangfu D. Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development. Journal of Visualized Experiments : Jove. PMID 28287608 DOI: 10.3791/55267  0.459
2017 Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D. Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell. PMID 28196600 DOI: 10.1016/J.Stem.2017.01.001  0.427
2017 Verma N, Zhu Z, Huangfu D. CRISPR/Cas-Mediated Knockin in Human Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1513: 119-140. PMID 27807834 DOI: 10.1007/978-1-4939-6539-7_9  0.354
2017 Soh CL, Huangfu D. CRISPR/Cas9-Mediated Mutagenesis of Human Pluripotent Stem Cells in Defined Xeno-Free E8 Medium. Methods in Molecular Biology (Clifton, N.J.). 1498: 57-78. PMID 27709569 DOI: 10.1007/978-1-4939-6472-7_5  0.382
2016 Wang Q, Zou Y, Nowotschin S, Kim SY, Li QV, Soh CL, Su J, Zhang C, Shu W, Xi Q, Huangfu D, Hadjantonakis AK, Massagué J. The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells. Cell Stem Cell. PMID 27889317 DOI: 10.1016/J.Stem.2016.10.002  0.373
2016 Zhu Z, Li QV, Lee K, Rosen BP, González F, Soh CL, Huangfu D. Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes. Cell Stem Cell. PMID 27133796 DOI: 10.1016/J.Stem.2016.03.015  0.424
2015 González F, Huangfu D. Mechanisms underlying the formation of induced pluripotent stem cells. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 26383234 DOI: 10.1002/Wdev.206  0.442
2015 Zhu Z, Verma N, González F, Shi ZD, Huangfu D. A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells. Stem Cell Reports. 4: 1103-11. PMID 26028531 DOI: 10.1016/J.Stemcr.2015.04.016  0.4
2015 Kotini AG, Chang CJ, Boussaad I, Delrow JJ, Dolezal EK, Nagulapally AB, Perna F, Fishbein GA, Klimek VM, Hawkins RD, Huangfu D, Murry CE, Graubert T, Nimer SD, Papapetrou EP. Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Nature Biotechnology. 33: 646-55. PMID 25798938 DOI: 10.1038/Nbt.3178  0.35
2014 Zhu Z, González F, Huangfu D. The iCRISPR platform for rapid genome editing in human pluripotent stem cells. Methods in Enzymology. 546: 215-50. PMID 25398343 DOI: 10.1016/B978-0-12-801185-0.00011-8  0.433
2014 Benitah SA, Bracken A, Dou Y, Huangfu D, Ivanova N, Koseki H, Laurent L, Lim DA, Meshorer E, Pombo A, Sander M, Xu GL. Stem cell epigenetics: looking forward. Cell Stem Cell. 14: 706-9. PMID 25032261 DOI: 10.1016/J.Stem.2014.05.011  0.368
2014 González F, Zhu Z, Shi ZD, Lelli K, Verma N, Li QV, Huangfu D. An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells. Cell Stem Cell. 15: 215-26. PMID 24931489 DOI: 10.1016/J.Stem.2014.05.018  0.412
2013 González F, Georgieva D, Vanoli F, Shi ZD, Stadtfeld M, Ludwig T, Jasin M, Huangfu D. Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Cell Reports. 3: 651-60. PMID 23478019 DOI: 10.1016/J.Celrep.2013.02.005  0.411
2013 Zhu Z, Huangfu D. Human pluripotent stem cells: an emerging model in developmental biology. Development (Cambridge, England). 140: 705-17. PMID 23362344 DOI: 10.1242/Dev.086165  0.43
2010 Salpeter SJ, Klein AM, Huangfu D, Grimsby J, Dor Y. Glucose and aging control the quiescence period that follows pancreatic beta cell replication. Development (Cambridge, England). 137: 3205-13. PMID 20823063 DOI: 10.1242/Jcs.080713  0.585
2009 Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, Egli D, Loh KM, Carter AC, Di Giorgio FP, Koszka K, Huangfu D, Akutsu H, Liu DR, Rubin LL, Eggan K. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell. 5: 491-503. PMID 19818703 DOI: 10.1016/J.Stem.2009.09.012  0.43
2008 Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nature Biotechnology. 26: 1269-75. PMID 18849973 DOI: 10.1038/Nbt.1502  0.731
2008 Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nature Biotechnology. 26: 795-7. PMID 18568017 DOI: 10.1038/Nbt1418  0.706
2007 Brennand K, Huangfu D, Melton D. All beta cells contribute equally to islet growth and maintenance. Plos Biology. 5: e163. PMID 17535113 DOI: 10.1371/Journal.Pbio.0050163  0.683
2007 Brennand K, Huangfu D, Melton D. Correction: All ß Cells Contribute Equally to Islet Growth and Maintenance Plos Biology. 5: e240. DOI: 10.1371/Journal.Pbio.0050240  0.644
2006 Huangfu D, Anderson KV. Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development (Cambridge, England). 133: 3-14. PMID 16339192 DOI: 10.1242/Dev.02169  0.573
2005 Huangfu D, Anderson KV. Cilia and Hedgehog responsiveness in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 102: 11325-30. PMID 16061793 DOI: 10.1073/Pnas.0505328102  0.611
2005 García-García MJ, Eggenschwiler JT, Caspary T, Alcorn HL, Wyler MR, Huangfu D, Rakeman AS, Lee JD, Feinberg EH, Timmer JR, Anderson KV. Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proceedings of the National Academy of Sciences of the United States of America. 102: 5913-9. PMID 15755804 DOI: 10.1073/Pnas.0501071102  0.691
2003 Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, Anderson KV. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature. 426: 83-7. PMID 14603322 DOI: 10.1038/Nature02061  0.745
2002 Caspary T, García-García MJ, Huangfu D, Eggenschwiler JT, Wyler MR, Rakeman AS, Alcorn HL, Anderson KV. Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling. Current Biology : Cb. 12: 1628-32. PMID 12372258 DOI: 10.1016/S0960-9822(02)01147-8  0.698
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