Maria B. Grant - Publications

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Cell Biology

231 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lin Y, Gil CH, Banno K, Yokoyama M, Wingo M, Go E, Prasain N, Liu Y, Hato T, Naito H, Wakabayashi T, Sominskaia M, Gao M, Chen K, Geng F, ... ... Grant MB, et al. ABCG2-Expressing Clonal Repopulating Endothelial Cells Serve to Form and Maintain Blood Vessels. Circulation. PMID 38682338 DOI: 10.1161/CIRCULATIONAHA.122.061833  0.346
2023 Dorofeeva I, Zhylkibayev A, Saltykova IV, Atigadda V, Adhikari B, Gorbatyuk OS, Grant MB, Gorbatyuk MS. Retinoid X Receptor Activation Prevents Diabetic Retinopathy in Murine Models. Cells. 12. PMID 37830574 DOI: 10.3390/cells12192361  0.335
2023 Dorofeeva I, Zhylkibayev A, Saltykova IV, Atigadda V, Adhikari B, Gorbatyuk O, Grant MB, Gorbatyuk M. Retinoid X Receptor activation prevents diabetic retinopathy in murine models. Biorxiv : the Preprint Server For Biology. PMID 37577690 DOI: 10.1101/2023.08.03.551887  0.335
2023 Adu-Agyeiwaah Y, Vieira CP, Asare-Bediako B, Li Calzi S, DuPont M, Floyd J, Boye S, Chiodo V, Busik JV, Grant MB. Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes. Translational Vision Science & Technology. 12: 20. PMID 37070938 DOI: 10.1167/tvst.12.4.20  0.311
2023 Prasad R, Adu-Agyeiwaah Y, Floyd JL, Asare-Bediako B, Li Calzi S, Chakraborty D, Harbour A, Rohella A, Busik JV, Li Q, Grant MB. Sustained ACE2 Expression by Probiotic Improves Integrity of Intestinal Lymphatics and Retinopathy in Type 1 Diabetic Model. Journal of Clinical Medicine. 12. PMID 36902558 DOI: 10.3390/jcm12051771  0.325
2022 Chaqour B, Grant MB, Lau LF, Wang B, Urbanski MM, Melendez-Vasquez CV. Atomic Force Microscopy-Based Measurements of Retinal Microvessel Stiffness in Mice with Endothelial-Specific Deletion of CCN1. Methods in Molecular Biology (Clifton, N.J.). 2582: 323-334. PMID 36370360 DOI: 10.1007/978-1-0716-2744-0_22  0.305
2022 Asare-Bediako B, Adu-Agyeiwaah Y, Abad A, Li Calzi S, Floyd JL, Prasad R, DuPont M, Asare-Bediako R, Bustelo XR, Grant MB. Hematopoietic Cells Influence Vascular Development in the Retina. Cells. 11. PMID 36291075 DOI: 10.3390/cells11203207  0.355
2022 Gheblawi M, de Oliveira AA, Williams VR, John R, Grant MB, Scholey JW, Oudit GY. An advanced endothelial murine HFpEF model: eNOS is critical for angiotensin 1-7 rescue of the diabetic phenotype. Journal of Molecular and Cellular Cardiology. 169: 10-12. PMID 35489389 DOI: 10.1016/j.yjmcc.2022.04.015  0.309
2022 Gil CH, Chakraborty D, Vieira CP, Prasain N, Calzi SL, Fortmann SD, Hu P, Banno K, Jamal M, Huang C, Sielski MS, Lin Y, Huang X, Dupont MD, Floyd JL, ... ... Grant MB, et al. Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice. Science Advances. 8: eabm5559. PMID 35245116 DOI: 10.1126/sciadv.abm5559  0.41
2021 Pitale PM, Saltykova IV, Adu-Agyeiwaah Y, Calzi SL, Satoh T, Akira S, Gorbatyuk O, Boulton ME, Pardue MT, Garvey WT, Athar M, Grant MB, Gorbatyuk MS. Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy. Diabetes. PMID 33975909 DOI: 10.2337/db20-1268  0.343
2021 Hammer SS, Vieira CP, McFarland D, Sandler M, Levitsky Y, Dorweiler TF, Lydic TA, Asare-Bediako B, Adu-Agyeiwaah Y, Sielski MS, Dupont M, Longhini AL, Li Calzi S, Chakraborty D, Seigel GM, ... ... Grant MB, et al. Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction. Diabetologia. PMID 33770194 DOI: 10.1007/s00125-021-05431-5  0.303
2020 Obukhov AG, Stevens BR, Prasad R, Calzi SL, Boulton ME, Raizada MK, Oudit GY, Grant MB. SARS-CoV-2 Infections and ACE2: Clinical Outcomes Linked With Increased Morbidity and Mortality in Individuals With Diabetes. Diabetes. PMID 32669391 DOI: 10.2337/Dbi20-0019  0.342
2020 Vieira CP, Fortmann SD, Hossain M, Longhini AL, Hammer SS, Asare-Bediako B, Crossman DK, Sielski MS, Adu-Agyeiwaah Y, Dupont M, Floyd JL, Li Calzi S, Lydic T, Welner RS, Blanchard GJ, ... ... Grant MB, et al. Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes. Jci Insight. 5. PMID 32641586 DOI: 10.1172/Jci.Insight.137230  0.387
2020 Floyd JL, Grant MB. The Gut-Eye Axis: Lessons Learned from Murine Models. Ophthalmology and Therapy. PMID 32617914 DOI: 10.1007/S40123-020-00278-2  0.315
2020 Qi X, Mitter SK, Yan Y, Busik JV, Grant MB, Boulton ME. Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic Retina. Cells. 9. PMID 32272782 DOI: 10.3390/Cells9040905  0.422
2020 Gheblawi M, Wang K, Viveiros A, Nguyen Q, Zhong JC, Turner AJ, Raizada MK, Grant MB, Oudit GY. Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System. Circulation Research. PMID 32264791 DOI: 10.1161/Circresaha.120.317015  0.323
2020 Asare-Bediako B, Noothi SK, Li Calzi S, Athmanathan B, Vieira CP, Adu-Agyeiwaah Y, Dupont M, Jones BA, Wang XX, Chakraborty D, Levi M, Nagareddy PR, Grant MB. Characterizing the Retinal Phenotype in the High-Fat Diet and Western Diet Mouse Models of Prediabetes. Cells. 9. PMID 32085589 DOI: 10.3390/Cells9020464  0.348
2020 Sreejit G, Abdel-Latif A, Athmanathan B, Annabathula R, Dhyani A, Noothi SK, Quaife-Ryan GA, Al-Sharea A, Pernes G, Dragoljevic D, Lal H, Schroder K, Hanaoka BY, Raman C, Grant MB, et al. Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis Following Myocardial Infarction. Circulation. PMID 31941367 DOI: 10.1161/Circulationaha.119.043833  0.3
2020 Vieira CP, Fortmann SD, Longhini AL, Lydic TA, Busik JV, Grant MB. 333-OR: DMHCA Reduces the Development of Diabetic Retinopathy (DR) in db/db Mice by Lowering Cholesterol Levels and Altering the Transcriptomic Profile of Hematopoietic Stem Cells Diabetes. 69. DOI: 10.2337/Db20-333-Or  0.423
2019 Li Calzi S, Cook T, Della Rocca DG, Zhang J, Shenoy V, Yan Y, Espejo A, Rathinasabapathy A, Jacobsen MH, Salazar T, Sandusky GE, Shaw LC, March K, Raizada MK, Pepine CJ, ... ... Grant MB, et al. Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model. Stem Cells International. 2019: 3945850. PMID 31781239 DOI: 10.1155/2019/3945850  0.361
2019 Li Calzi S, Shaw LC, Moldovan L, Shelley WC, Qi X, Racette L, Quigley JL, Fortmann SD, Boulton ME, Yoder MC, Grant MB. Progenitor cell combination normalizes retinal vascular development in the oxygen-induced retinopathy (OIR) model. Jci Insight. 4. PMID 31672944 DOI: 10.1172/Jci.Insight.129224  0.483
2019 Duan Y, Prasad R, Feng D, Beli E, Li Calzi S, Longhini ALF, Lamendella R, Floyd JL, Dupont M, Noothi S, Sreejit G, Athmanathan B, Wright J, Jensen AR, Oudit GY, ... ... Grant MB, et al. Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency. Circulation Research. PMID 31610731 DOI: 10.1161/Circresaha.119.315743  0.458
2019 Beli E, Prabakaran S, Krishnan P, Evans-Molina C, Grant MB. Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Changes in Circulating Metabolites in Type 2 Diabetic db/db Mice. Nutrients. 11. PMID 31569518 DOI: 10.3390/Nu11102310  0.34
2019 Verma A, Xu K, Du T, Zhu P, Liang Z, Liao S, Zhang J, Raizada MK, Grant MB, Li Q. Expression of Human ACE2 in Lactobacillus and Beneficial Effects in Diabetic Retinopathy in Mice. Molecular Therapy. Methods & Clinical Development. 14: 161-170. PMID 31380462 DOI: 10.1016/J.Omtm.2019.06.007  0.42
2019 Lee S, Ahad A, Luu M, Moon S, Caesar J, Cardoso WV, Grant M, Chaqour B. CCN1-YAP Feedback Loop Regulates Physiological and Pathological Angiogenesis. Molecular and Cellular Biology. PMID 31262999 DOI: 10.1128/Mcb.00107-19  0.43
2019 Longhini ALF, Salazar TE, Vieira C, Trinh T, Duan Y, Pay LM, Li Calzi S, Losh M, Johnston NA, Xie H, Kim M, Hunt RJ, Yoder MC, Santoro D, McCarrel TM, ... Grant MB, et al. Peripheral blood-derived mesenchymal stem cells demonstrate immunomodulatory potential for therapeutic use in horses. Plos One. 14: e0212642. PMID 30870461 DOI: 10.1371/Journal.Pone.0212642  0.381
2019 Chen X, Duan Y, Riley AM, Welch MA, White FA, Grant MB, Obukhov AG. Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons. Molecules (Basel, Switzerland). 24. PMID 30795543 DOI: 10.3390/Molecules24040775  0.315
2019 DUPONT MD, LONGHINI AL, SREEJIT G, PRASAD R, NAGAREDDY P, GRANT MB. 603-P: Circulating Inflammatory Cells and Inflammasome Activation in Diabetics with Diabetic Retinopathy (DR) Diabetes. 68: 603-P. DOI: 10.2337/Db19-603-P  0.397
2019 PRASAD R, DUAN Y, FLOYD JL, GRANT MB. 48-OR: Gut Dysbiosis Promotes Diabetic Retinopathy (DR) through TLR-2 Activation by Peptidoglycan (PGN) in Angiotensin Converting Enzyme 2 (ACE2) Deficient Type 1 Diabetic (T1D) Mice Diabetes. 68: 48-OR. DOI: 10.2337/Db19-48-Or  0.437
2019 VIEIRA CP, LONGHINI AL, CALZI SL, DESIREE` DUPONT M, BUSIK JV, GRANT MB. 47-OR: Regulation of SIRT1 as a Target of Prevention of Diabetic Retinopathy in db/db Mice Diabetes. 68: 47-OR. DOI: 10.2337/Db19-47-Or  0.448
2019 Fortmann SD, Grant MB. Molecular mechanisms of retinal ischemia Current Opinion in Physiology. 7: 41-48. DOI: 10.1016/J.Cophys.2018.12.008  0.399
2018 Saadane A, Mast N, Trichonas G, Chakraborty D, Hammer S, Busik JV, Grant MB, Pikuleva IA. Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in CYP46A1-Mediated Cholesterol Removal. The American Journal of Pathology. PMID 30448403 DOI: 10.1016/J.Ajpath.2018.10.013  0.425
2018 McAnally D, Siddiquee K, Gomaa A, Szabo A, Vasile S, Maloney PR, Divlianska DB, Peddibhotla S, Morfa CJ, Hershberger P, Falter R, Williamson R, Terry DB, Farjo R, Pinkerton AB, ... ... Grant MB, et al. Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization. Plos One. 13: e0202436. PMID 30208056 DOI: 10.1371/Journal.Pone.0202436  0.419
2018 Duan Y, Beli E, Li Calzi S, Quigley JL, Miller RC, Moldovan L, Feng D, Salazar TE, Hazra S, Al-Sabah J, Chalam KV, Le Phuong Trinh T, Meroueh M, Markel TA, Murray MC, ... ... Grant MB, et al. Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction. Stem Cells (Dayton, Ohio). PMID 29761600 DOI: 10.1002/Stem.2848  0.756
2018 Beli E, Yan Y, Moldovan L, Vieira CP, Gao R, Duan Y, Prasad R, Bhatwadekar A, White FA, Townsend S, Chan L, Ryan CN, Morton D, Moldovan EG, Chu FI, ... ... Grant MB, et al. Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice. Diabetes. PMID 29712667 DOI: 10.2337/Db18-0158  0.402
2018 Malek G, Busik J, Grant MB, Choudhary M. Models of retinal diseases and their applicability in drug discovery. Expert Opinion On Drug Discovery. 1-19. PMID 29382242 DOI: 10.1080/17460441.2018.1430136  0.333
2018 LONGHINI AL, THINSCHMIDT J, BOULTON M, KING MA, GRANT MB. Loss of Hypothalamic Somatostatin (SST) Contributes to Bone Marrow (BM) Dysfunction and Diabetic Retinopathy (DR) in Type 2 Diabetic Rats Diabetes. 67: 238-OR. DOI: 10.2337/Db18-238-Or  0.35
2018 DUAN Y, FENG D, BELI E, CALZI SL, LONGHINI ALF, LAMENDELLA R, WRIGHT JR, MARKEL TA, OBUKHOV AG, GRANT MB. Angiotensin-Converting Enzyme 2 Deficiency Increases Translocation of Gut Bacteria by Depletion of Bone Marrow-Derived Circulating Angiogenic Cells Diabetes. 67: 1899-P. DOI: 10.2337/Db18-1899-P  0.401
2018 Calzi SL, Vieira CP, Chakraborty D, Jayagopal A, Yoder MC, Grant MB. “Seeing” iPSCs in the Retina During Retinal Repair in Diabetic Retinopathy Microscopy and Microanalysis. 24: 2306-2307. DOI: 10.1017/S1431927618012011  0.415
2018 Loghmani MT, Metzger T, Kim MS, Grant M. Electro-acupuncture and massage mobilizes mesenchymal stem cell into circulation in canines Journal of Bodywork and Movement Therapies. 22: 871. DOI: 10.1016/J.Jbmt.2018.09.067  0.357
2017 Lakshmikanthan S, Sobczak M, Li Calzi S, Shaw L, Grant MB, Chrzanowska-Wodnicka M. Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of endothelial barrier. Journal of Cell Science. PMID 29222111 DOI: 10.1242/Jcs.207605  0.425
2017 Cole-Jeffrey CT, Pepine CJ, Katovich MJ, Grant MB, Raizada MK, Hazra S. Beneficial Effects Of Angiotensin-(1-7) On Cd34 + Cells From Heart Failure Patients. Journal of Cardiovascular Pharmacology. PMID 29140957 DOI: 10.1097/Fjc.0000000000000556  0.705
2017 Caballero S, Kent DL, Sengupta N, Li Calzi S, Shaw L, Beli E, Moldovan L, Dominguez JM, Moorthy RS, Grant MB. Bone Marrow-Derived Cell Recruitment to the Neurosensory Retina and Retinal Pigment Epithelial Cell Layer Following Subthreshold Retinal Phototherapy. Investigative Ophthalmology & Visual Science. 58: 5164-5176. PMID 29049716 DOI: 10.1167/Iovs.16-20736  0.778
2017 Bhatwadekar AD, Duan Y, Korahw M, Thinschmidt JS, Hu P, Leley SP, Caballero S, Shaw L, Busik J, Grant MB. Hematopoietic stem/progenitor involvement in retinal microvascular repair during diabetes: Implications for bone marrow rejuvenation. Vision Research. PMID 29042190 DOI: 10.1016/J.Visres.2017.06.016  0.4
2017 Moldovan L, Barnard A, Gil CH, Lin Y, Grant MB, Yoder MC, Prasain N, Moldovan NI. iPSC-Derived Vascular Cell Spheroids as Building Blocks for Scaffold-Free Biofabrication. Biotechnology Journal. PMID 29030959 DOI: 10.1002/Biot.201700444  0.392
2017 Hu P, Hunt NH, Arfuso F, Shaw LC, Uddin MN, Zhu M, Devasahayam R, Adamson SJ, Benson VL, Chan-Ling T, Grant MB. Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina. Investigative Ophthalmology & Visual Science. 58: 5043-5055. PMID 28980000 DOI: 10.1167/Iovs.17-21654  0.408
2017 Hammer SS, Beli E, Kady N, Wang Q, Wood K, Lydic TA, Malek G, Saban DR, Wang XX, Hazra S, Levi M, Busik JV, Grant MB. The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor. Ebiomedicine. PMID 28774737 DOI: 10.1016/J.Ebiom.2017.07.008  0.726
2017 Yan Y, Gao R, Trinh TLP, Grant MB. Immunodeficiency in Pancreatic Adenocarcinoma with Diabetes Revealed by Comparative Genomics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28684632 DOI: 10.1158/1078-0432.Ccr-17-0250  0.352
2017 Lee S, Elaskandrany M, Lau LF, Lazzaro D, Grant MB, Chaqour B. Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy. Scientific Reports. 7: 1405. PMID 28469167 DOI: 10.1038/S41598-017-01585-8  0.476
2017 Kady N, Yan Y, Salazar T, Wang Q, Chakravarthy H, Huang C, Beli E, Navitskaya S, Grant M, Busik J. Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34(+) circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes. Journal of Clinical Lipidology. PMID 28457994 DOI: 10.1016/J.Jacl.2017.03.007  0.499
2017 Bhatwadekar AD, Beli E, Yanpeng D, Chen J, Luo Q, Alex A, Caballero S, Dominguez JM, Salazar TE, Busik JV, Segal MS, Grant MB. Conditional Deletion of Bmal1 Accentuates Microvascular and Macrovascular Injury. The American Journal of Pathology. PMID 28432873 DOI: 10.1016/J.Ajpath.2017.02.014  0.441
2017 Beli E, Dominguez JM, Hu P, Thinschmidt JS, Caballero S, Calzi SL, Luo D, Shanmugam S, Salazar TE, Duan Y, Boulton ME, Mohr S, Abcouwer SF, Saban DR, Harrison JK, ... Grant MB, et al. Erratum to: CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes. Journal of Molecular Medicine (Berlin, Germany). PMID 28421250 DOI: 10.1007/S00109-017-1530-8  0.37
2017 Basavarajappa HD, Sulaiman RS, Qi X, Shetty T, Sheik Pran Babu S, Sishtla KL, Lee B, Quigley J, Alkhairy S, Briggs CM, Gupta K, Tang B, Shadmand M, Grant MB, Boulton ME, et al. Ferrochelatase is a therapeutic target for ocular neovascularization. Embo Molecular Medicine. PMID 28377496 DOI: 10.15252/Emmm.201606561  0.401
2017 Salazar TE, Richardson MR, Beli E, Ripsch MS, George J, Kim Y, Duan Y, Moldovan L, Yan Y, Bhatwadekar A, Jadhav V, Smith JA, McGorray S, Bertone AL, Traktuev DO, ... ... Grant MB, et al. Electroacupuncture Promotes CNS-Dependent Release of Mesenchymal Stem Cells. Stem Cells (Dayton, Ohio). PMID 28299842 DOI: 10.1002/Stem.2613  0.338
2017 Song C, Mitter SK, Qi X, Beli E, Rao HV, Ding J, Ip CS, Gu H, Akin D, Dunn WA, Bowes Rickman C, Lewin AS, Grant MB, Boulton ME. Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy. Plos One. 12: e0171940. PMID 28222108 DOI: 10.1371/Journal.Pone.0171940  0.306
2017 Qi X, Pay SL, Yan Y, Thomas J, Lewin AS, Chang LJ, Grant MB, Boulton ME. Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28202390 DOI: 10.1016/J.Ymthe.2017.01.015  0.399
2016 Trinh TLP, Li Calzi S, Shaw LC, Yoder MC, Grant MB. Promoting vascular repair in the retina: can stem/progenitor cells help? Eye and Brain. 8: 113-122. PMID 28539806 DOI: 10.2147/EB.S94451  0.316
2016 Park SS, Moisseiev E, Bauer G, Anderson JD, Grant MB, Zam A, Zawadzki RJ, Werner JS, Nolta JA. Advances in bone marrow stem cell therapy for retinal dysfunction. Progress in Retinal and Eye Research. PMID 27784628 DOI: 10.1016/J.Preteyeres.2016.10.002  0.457
2016 Jadhav V, Luo Q, M Dominguez J, Al-Sabah J, Chaqour B, Grant MB, Bhatwadekar AD. Per2-Mediated Vascular Dysfunction Is Caused by the Upregulation of the Connective Tissue Growth Factor (CTGF). Plos One. 11: e0163367. PMID 27662578 DOI: 10.1371/Journal.Pone.0163367  0.403
2016 Wang Q, Navitskaya S, Chakravarthy H, Huang C, Kady N, Lydic TA, Chen YE, Yin KJ, Powell FL, Martin PM, Grant MB, Busik JV. Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy. Ebiomedicine. PMID 27531575 DOI: 10.1016/J.Ebiom.2016.08.013  0.354
2016 Beli E, Dominguez JM, Hu P, Thinschmidt JS, Caballero S, Li Calzi S, Luo D, Shanmugam S, Salazar TE, Duan Y, Boulton ME, Mohr S, Abcouwer SF, Saban DR, Harrison JK, ... Grant MB, et al. CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes. Journal of Molecular Medicine (Berlin, Germany). PMID 27344677 DOI: 10.1007/S00109-016-1433-0  0.449
2016 Wert KJ, Mahajan VB, Zhang L, Yan Y, Li Y, Tosi J, Hsu CW, Nagasaki T, Janisch KM, Grant MB, Mahajan M, Bassuk AG, Tsang SH. Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy. Signal Transduction and Targeted Therapy. 1. PMID 27195131 DOI: 10.1038/Sigtrans.2016.5  0.43
2016 Dominguez JM, Hu P, Caballero S, Moldovan L, Verma A, Oudit GY, Li Q, Grant MB. Adeno-Associated Virus Overexpression of Angiotensin-Converting Enzyme-2 Reverses Diabetic Retinopathy in Type 1 Diabetes in Mice. The American Journal of Pathology. PMID 27178803 DOI: 10.1016/J.Ajpath.2016.01.023  0.408
2016 Thinschmidt JS, Perez LM, Febo M, Caballero S, King MA, White FA, Grant MB. Depressed basal hypothalamic neuronal activity in type-1 diabetic mice is correlated with proinflammatory secretion of HMBG1. Neuroscience Letters. PMID 26777426 DOI: 10.1016/J.Neulet.2016.01.014  0.369
2016 Chakravarthy H, Beli E, Navitskaya S, O'Reilly S, Wang Q, Kady N, Huang C, Grant MB, Busik JV. Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy. Plos One. 11: e0146829. PMID 26760976 DOI: 10.1371/Journal.Pone.0146829  0.489
2016 Qian Q, Mitter SK, Pay SL, Qi X, Rickman CB, Grant MB, Boulton ME. A Non-Canonical Role for β-Secretase in the Retina. Advances in Experimental Medicine and Biology. 854: 333-9. PMID 26427429 DOI: 10.1007/978-3-319-17121-0_44  0.349
2015 Chakravarthy H, Navitskaya S, O'Reilly S, Gallimore J, Mize H, Beli E, Wang Q, Kady N, Huang C, Blanchard GJ, Grant MB, Busik JV. Role of acid sphingomyelinase in shifting the balance between pro-inflammatory and reparative bone marrow cells in diabetic retinopathy. Stem Cells (Dayton, Ohio). PMID 26676316 DOI: 10.1002/Stem.2259  0.495
2015 Taylor DA, Perin EC, Willerson JT, Zierold C, Resende M, Carlson M, Nestor B, Wise E, Orozco A, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Traverse JH, Cooke JP, ... ... Grant MB, et al. Identification of Bone Marrow Cell Subpopulations Associated with Improved Functional Outcomes in Patients with Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial. Cell Transplantation. PMID 26590374 DOI: 10.3727/096368915X689901  0.325
2015 Bhatwadekar AD, Duan Y, Chakravarthy H, Korah M, Caballero S, Busik JV, Grant MB. Ataxia Telangiectasia Mutated (ATM) Dysregulation Results in Diabetic Retinopathy. Stem Cells (Dayton, Ohio). PMID 26502796 DOI: 10.1002/Stem.2235  0.462
2015 Bhatwadekar AD, Yan Y, Stepps V, Hazra S, Korah M, Bartelmez S, Chaqour B, Grant MB. miR-92a Corrects CD34+ Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation. Diabetes. PMID 26283734 DOI: 10.2337/Db15-0521  0.72
2015 Yan L, Lee S, Lazzaro DR, Aranda J, Grant MB, Chaqour B. Single and Compound Knockouts of MicroRNA (miRNA)-155 and its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia. The Journal of Biological Chemistry. PMID 26242736 DOI: 10.1074/Jbc.M115.646950  0.327
2015 Chintala H, Krupska I, Yan L, Lau L, Grant M, Chaqour B. The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling Development (Cambridge). 142: 2364-2374. PMID 26002917 DOI: 10.1242/Dev.121913  0.414
2015 Busik JV, Grant MB. Wnting out ocular neovascularization: using nanoparticle delivery of very-low density lipoprotein receptor extracellular domain as Wnt pathway inhibitor in the retina. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1046-7. PMID 25903649 DOI: 10.1161/Atvbaha.115.305395  0.44
2015 Hu P, Thinschmidt JS, Caballero S, Adamson S, Cole L, Chan-Ling T, Grant MB. Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice. American Journal of Physiology. Endocrinology and Metabolism. 308: E688-98. PMID 25714673 DOI: 10.1152/Ajpendo.00504.2014  0.396
2015 Dominguez JM, Yorek MA, Grant MB. Combination therapies prevent the neuropathic, proinflammatory characteristics of bone marrow in streptozotocin-induced diabetic rats. Diabetes. 64: 643-53. PMID 25204979 DOI: 10.2337/Db14-0433  0.412
2014 Hudson N, Powner MB, Sarker MH, Burgoyne T, Campbell M, Ockrim ZK, Martinelli R, Futter CE, Grant MB, Fraser PA, Shima DT, Greenwood J, Turowski P. Differential apicobasal VEGF signaling at vascular blood-neural barriers. Developmental Cell. 30: 541-52. PMID 25175707 DOI: 10.1016/J.Devcel.2014.06.027  0.354
2014 Balaiya S, Grant MB, Priluck J, Chalam KV. Growth factors/chemokines in diabetic vitreous and aqueous alter the function of bone marrow-derived progenitor (CD34⁺) cells in humans. American Journal of Physiology. Endocrinology and Metabolism. 307: E695-702. PMID 25159325 DOI: 10.1152/Ajpendo.00253.2014  0.451
2014 Cogle CR, Wise E, Meacham AM, Zierold C, Traverse JH, Henry TD, Perin EC, Willerson JT, Ellis SG, Carlson M, Zhao DX, Bolli R, Cooke JP, Anwaruddin S, Bhatnagar A, ... ... Grant MB, et al. Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes. Circulation Research. 115: 867-74. PMID 25136078 DOI: 10.1161/Circresaha.115.304353  0.303
2014 Wang Q, Bozack SN, Yan Y, Boulton ME, Grant MB, Busik JV. Regulation of retinal inflammation by rhythmic expression of MiR-146a in diabetic retina. Investigative Ophthalmology & Visual Science. 55: 3986-94. PMID 24867582 DOI: 10.1167/Iovs.13-13076  0.349
2014 Wang Q, Tikhonenko M, Bozack SN, Lydic TA, Yan L, Panchy NL, McSorley KM, Faber MS, Yan Y, Boulton ME, Grant MB, Busik JV. Changes in the daily rhythm of lipid metabolism in the diabetic retina. Plos One. 9: e95028. PMID 24736612 DOI: 10.1371/Journal.Pone.0095028  0.397
2014 Jarajapu YP, Hazra S, Segal M, LiCalzi S, Jhadao C, Qian K, Mitter SK, Raizada MK, Boulton ME, Grant MB. Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms. Plos One. 9: e93965. PMID 24713821 DOI: 10.1371/Journal.Pone.0093965  0.758
2014 Keats EC, Dominguez JM, Grant MB, Khan ZA. Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced adipogenesis. Stem Cells (Dayton, Ohio). 32: 1649-60. PMID 24496952 DOI: 10.1002/Stem.1659  0.454
2014 Rowan S, Weikel K, Chang ML, Nagel BA, Thinschmidt JS, Carey A, Grant MB, Fliesler SJ, Smith D, Taylor A. Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice. Investigative Ophthalmology & Visual Science. 55: 492-501. PMID 24370827 DOI: 10.1167/Iovs.13-12413  0.303
2013 Hazra S, Stepps V, Bhatwadekar AD, Caballero S, Boulton ME, Higgins PJ, Nikonova EV, Pepine CJ, Thut C, Finney EM, Stone DJ, Bartelmez SH, Grant MB. Enhancing the function of CD34(+) cells by targeting plasminogen activator inhibitor-1. Plos One. 8: e79067. PMID 24223881 DOI: 10.1371/Journal.Pone.0079067  0.754
2013 Hu P, Thinschmidt JS, Yan Y, Hazra S, Bhatwadekar A, Caballero S, Salazar T, Miyan JA, Li W, Derbenev A, Zsombok A, Tikhonenko M, Dominguez JM, McGorray SP, Saban DR, ... ... Grant MB, et al. CNS inflammation and bone marrow neuropathy in type 1 diabetes. The American Journal of Pathology. 183: 1608-20. PMID 24160325 DOI: 10.1016/J.Ajpath.2013.07.009  0.718
2013 Choi J, Lin A, Shrier E, Lau LF, Grant MB, Chaqour B. Degradome products of the matricellular protein CCN1 as modulators of pathological angiogenesis in the retina. The Journal of Biological Chemistry. 288: 23075-89. PMID 23798676 DOI: 10.1074/Jbc.M113.475418  0.412
2013 Nguyen DV, Li Calzi S, Shaw LC, Kielczewski JL, Korah HE, Grant MB. An ocular view of the IGF-IGFBP system. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 23: 45-52. PMID 23578754 DOI: 10.1016/J.Ghir.2013.03.001  0.776
2013 Caballero S, Hazra S, Bhatwadekar A, Li Calzi S, Paradiso LJ, Miller LP, Chang LJ, Kern TS, Grant MB. Circulating mononuclear progenitor cells: differential roles for subpopulations in repair of retinal vascular injury. Investigative Ophthalmology & Visual Science. 54: 3000-9. PMID 23572102 DOI: 10.1167/Iovs.12-10280  0.755
2013 Liu L, Qi X, Chen Z, Shaw L, Cai J, Smith LH, Grant MB, Boulton ME. Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization. The American Journal of Pathology. 182: 1412-24. PMID 23395094 DOI: 10.1016/J.Ajpath.2012.12.020  0.418
2013 Tikhonenko M, Lydic TA, Opreanu M, Li Calzi S, Bozack S, McSorley KM, Sochacki AL, Faber MS, Hazra S, Duclos S, Guberski D, Reid GE, Grant MB, Busik JV. N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function. Plos One. 8: e55177. PMID 23383097 DOI: 10.1371/Journal.Pone.0055177  0.759
2013 Jarajapu YP, Bhatwadekar AD, Caballero S, Hazra S, Shenoy V, Medina R, Kent D, Stitt AW, Thut C, Finney EM, Raizada MK, Grant MB. Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors. Diabetes. 62: 1258-69. PMID 23230080 DOI: 10.2337/Db12-0808  0.757
2013 Bhatwadekar AD, Yan Y, Qi X, Thinschmidt JS, Neu MB, Li Calzi S, Shaw LC, Dominiguez JM, Busik JV, Lee C, Boulton ME, Grant MB. Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow. Diabetes. 62: 273-82. PMID 23193187 DOI: 10.2337/Db12-0172  0.463
2013 Hazra S, Jarajapu YP, Stepps V, Caballero S, Thinschmidt JS, Sautina L, Bengtsson N, Licalzi S, Dominguez J, Kern TS, Segal MS, Ash JD, Saban DR, Bartelmez SH, Grant MB. Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model. Diabetologia. 56: 644-53. PMID 23192694 DOI: 10.1007/S00125-012-2781-0  0.754
2012 Nguyen DV, Shaw LC, Grant MB. Inflammation in the pathogenesis of microvascular complications in diabetes. Frontiers in Endocrinology. 3: 170. PMID 23267348 DOI: 10.3389/Fendo.2012.00170  0.372
2012 Chintala H, Liu H, Parmar R, Kamalska M, Kim YJ, Lovett D, Grant MB, Chaqour B. Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene. The Journal of Biological Chemistry. 287: 40570-85. PMID 23048035 DOI: 10.1074/Jbc.M112.386565  0.382
2012 Jun JY, Zubcevic J, Qi Y, Afzal A, Carvajal JM, Thinschmidt JS, Grant MB, Mocco J, Raizada MK. Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension. Hypertension. 60: 1316-23. PMID 23045460 DOI: 10.1161/Hypertensionaha.112.199547  0.327
2012 Cai J, Qi X, Kociok N, Skosyrski S, Emilio A, Ruan Q, Han S, Liu L, Chen Z, Bowes Rickman C, Golde T, Grant MB, Saftig P, Serneels L, de Strooper B, et al. β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment. Embo Molecular Medicine. 4: 980-91. PMID 22903875 DOI: 10.1002/Emmm.201101084  0.428
2012 Hazra S, Rasheed A, Bhatwadekar A, Wang X, Shaw LC, Patel M, Caballero S, Magomedova L, Solis N, Yan Y, Wang W, Thinschmidt JS, Verma A, Li Q, Levi M, ... ... Grant MB, et al. Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes. Diabetes. 61: 3270-9. PMID 22891211 DOI: 10.2337/Db11-1596  0.754
2012 Jarajapu YP, Cai J, Yan Y, Li Calzi S, Kielczewski JL, Hu P, Shaw LC, Firth SM, Chan-Ling T, Boulton ME, Baxter RC, Grant MB. Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3. Plos One. 7: e39398. PMID 22792172 DOI: 10.1371/Journal.Pone.0039398  0.775
2012 Yellowlees Douglas J, Bhatwadekar AD, Li Calzi S, Shaw LC, Carnegie D, Caballero S, Li Q, Stitt AW, Raizada MK, Grant MB. Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Progress in Retinal and Eye Research. 31: 481-94. PMID 22609081 DOI: 10.1016/J.Preteyeres.2012.04.005  0.445
2012 Patel VB, Bodiga S, Basu R, Das SK, Wang W, Wang Z, Lo J, Grant MB, Zhong J, Kassiri Z, Oudit GY. Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis. Circulation Research. 110: 1322-35. PMID 22474255 DOI: 10.1161/Circresaha.112.268029  0.42
2012 Jadhao CS, Bhatwadekar AD, Jiang Y, Boulton ME, Steinle JJ, Grant MB. Nerve growth factor promotes endothelial progenitor cell-mediated angiogenic responses. Investigative Ophthalmology & Visual Science. 53: 2030-7. PMID 22410557 DOI: 10.1167/Iovs.11-8430  0.406
2012 Park SS, Caballero S, Bauer G, Shibata B, Roth A, Fitzgerald PG, Forward KI, Zhou P, McGee J, Telander DG, Grant MB, Nolta JA. Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury. Investigative Ophthalmology & Visual Science. 53: 986-94. PMID 22247454 DOI: 10.1167/Iovs.11-8833  0.393
2012 Qi X, Cai J, Ruan Q, Liu L, Boye SL, Chen Z, Hauswirth WW, Ryals RC, Shaw L, Caballero S, Grant MB, Boulton ME. γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines. Investigative Ophthalmology & Visual Science. 53: 574-85. PMID 22205609 DOI: 10.1167/Iovs.11-8728  0.393
2012 Mitter SK, Rao HV, Qi X, Cai J, Sugrue A, Dunn WA, Grant MB, Boulton ME. Autophagy in the retina: a potential role in age-related macular degeneration. Advances in Experimental Medicine and Biology. 723: 83-90. PMID 22183319 DOI: 10.1007/978-1-4614-0631-0_12  0.32
2012 Segal MS, Sautina L, Li S, Diao Y, Agoulnik AI, Kielczewski J, McGuane JT, Grant MB, Conrad KP. Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice. Blood. 119: 629-36. PMID 22028476 DOI: 10.1182/Blood-2011-04-346007  0.754
2012 Verma A, Shan Z, Lei B, Yuan L, Liu X, Nakagawa T, Grant MB, Lewin AS, Hauswirth WW, Raizada MK, Li Q. ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 28-36. PMID 21792177 DOI: 10.1038/Mt.2011.155  0.415
2011 Cai J, Chen Z, Ruan Q, Han S, Liu L, Qi X, Boye SL, Hauswirth WW, Grant MB, Boulton ME. γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. The Journal of Biological Chemistry. 286: 42514-23. PMID 22016384 DOI: 10.1074/Jbc.M111.296590  0.4
2011 Kielczewski JL, Li Calzi S, Shaw LC, Cai J, Qi X, Ruan Q, Wu L, Liu L, Hu P, Chan-Ling T, Mames RN, Firth S, Baxter RC, Turowski P, Busik JV, ... ... Grant MB, et al. Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Investigative Ophthalmology & Visual Science. 52: 8278-86. PMID 21931131 DOI: 10.1167/Iovs.11-8167  0.737
2011 Opreanu M, Tikhonenko M, Bozack S, Lydic TA, Reid GE, McSorley KM, Sochacki A, Perez GI, Esselman WJ, Kern T, Kolesnick R, Grant MB, Busik JV. The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models. Diabetes. 60: 2370-8. PMID 21771974 DOI: 10.2337/Db10-0550  0.428
2011 Cai J, Wu L, Qi X, Li Calzi S, Caballero S, Shaw L, Ruan Q, Grant MB, Boulton ME. PEDF regulates vascular permeability by a γ-secretase-mediated pathway. Plos One. 6: e21164. PMID 21695048 DOI: 10.1371/Journal.Pone.0021164  0.419
2011 Jarajapu YP, Caballero S, Verma A, Nakagawa T, Lo MC, Li Q, Grant MB. Blockade of NADPH oxidase restores vasoreparative function in diabetic CD34+ cells. Investigative Ophthalmology & Visual Science. 52: 5093-104. PMID 21676908 DOI: 10.1167/Iovs.10-70911  0.483
2011 Shaw LC, Neu MB, Grant MB. Cell-based therapies for diabetic retinopathy. Current Diabetes Reports. 11: 265-74. PMID 21611766 DOI: 10.1007/S11892-011-0197-8  0.457
2011 McGuane JT, Debrah JE, Sautina L, Jarajapu YP, Novak J, Rubin JP, Grant MB, Segal M, Conrad KP. Relaxin induces rapid dilation of rodent small renal and human subcutaneous arteries via PI3 kinase and nitric oxide. Endocrinology. 152: 2786-96. PMID 21558316 DOI: 10.1210/En.2010-1126  0.329
2011 Cai J, Wu L, Qi X, Shaw L, Li Calzi S, Caballero S, Jiang WG, Vinores SA, Antonetti D, Ahmed A, Grant MB, Boulton ME. Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability. Plos One. 6: e18076. PMID 21464949 DOI: 10.1371/Journal.Pone.0018076  0.387
2011 Kielczewski JL, Hu P, Shaw LC, Li Calzi S, Mames RN, Gardiner TA, McFarland E, Chan-Ling T, Grant MB. Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury. The American Journal of Pathology. 178: 1517-28. PMID 21435441 DOI: 10.1016/J.Ajpath.2010.12.031  0.797
2011 Kirabo A, Kearns PN, Jarajapu YP, Sasser JM, Oh SP, Grant MB, Kasahara H, Cardounel AJ, Baylis C, Wagner KU, Sayeski PP. Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species. Cardiovascular Research. 91: 171-9. PMID 21354995 DOI: 10.1093/Cvr/Cvr059  0.307
2011 Hasan A, Pokeza N, Shaw L, Lee HS, Lazzaro D, Chintala H, Rosenbaum D, Grant MB, Chaqour B. The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy. The Journal of Biological Chemistry. 286: 9542-54. PMID 21212276 DOI: 10.1074/Jbc.M110.198689  0.467
2011 Caballero S, Yang R, Grant MB, Chaqour B. Selective blockade of cytoskeletal actin remodeling reduces experimental choroidal neovascularization. Investigative Ophthalmology & Visual Science. 52: 2490-6. PMID 21178140 DOI: 10.1167/Iovs.10-6351  0.334
2011 Nakagawa T, Tanabe K, Croker BP, Johnson RJ, Grant MB, Kosugi T, Li Q. Endothelial dysfunction as a potential contributor in diabetic nephropathy. Nature Reviews. Nephrology. 7: 36-44. PMID 21045790 DOI: 10.1038/Nrneph.2010.152  0.429
2010 Bhatwadekar AD, Shaw LC, Grant MB. Promise of endothelial progenitor cell for treatment of diabetic retinopathy. Expert Review of Endocrinology & Metabolism. 5: 29-37. PMID 23678364 DOI: 10.1586/Eem.09.75  0.521
2010 Li Calzi S, Neu MB, Shaw LC, Grant MB. Endothelial progenitor dysfunction in the pathogenesis of diabetic retinopathy: treatment concept to correct diabetes-associated deficits. The Epma Journal. 1: 88-100. PMID 21494317 DOI: 10.1007/S13167-010-0011-8  0.526
2010 Bhatwadekar AD, Guerin EP, Jarajapu YP, Caballero S, Sheridan C, Kent D, Kennedy L, Lansang MC, Ruscetti FW, Pepine CJ, Higgins PJ, Bartelmez SH, Grant MB. Transient inhibition of transforming growth factor-beta1 in human diabetic CD34+ cells enhances vascular reparative functions. Diabetes. 59: 2010-9. PMID 20460428 DOI: 10.2337/Db10-0287  0.434
2010 Li Q, Verma A, Han PY, Nakagawa T, Johnson RJ, Grant MB, Campbell-Thompson M, Jarajapu YP, Lei B, Hauswirth WW. Diabetic eNOS-knockout mice develop accelerated retinopathy. Investigative Ophthalmology & Visual Science. 51: 5240-6. PMID 20435587 DOI: 10.1167/Iovs.09-5147  0.471
2010 Jarajapu YP, Grant MB. The promise of cell-based therapies for diabetic complications: challenges and solutions. Circulation Research. 106: 854-69. PMID 20299675 DOI: 10.1161/Circresaha.109.213140  0.48
2010 Li Calzi S, Neu MB, Shaw LC, Kielczewski JL, Moldovan NI, Grant MB. EPCs and pathological angiogenesis: when good cells go bad. Microvascular Research. 79: 207-16. PMID 20188747 DOI: 10.1016/J.Mvr.2010.02.011  0.776
2010 Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T. Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice. American Journal of Physiology. Renal Physiology. 298: F609-16. PMID 20015944 DOI: 10.1152/Ajprenal.00377.2009  0.416
2010 Sengupta N, Afzal A, Caballero S, Chang KH, Shaw LC, Pang JJ, Bond VC, Bhutto I, Baba T, Lutty GA, Grant MB. Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Investigative Ophthalmology & Visual Science. 51: 2697-704. PMID 20007826 DOI: 10.1167/Iovs.09-4137  0.771
2010 Afzal A, Caballero S, Palii SS, Jurczyk S, Pardue M, Geroski D, Edelhauser H, Hochhaus G, Kim M, Franklin A, Shapiro G, Grant MB. Targeting retinal and choroid neovascularization using the small molecule inhibitor carboxyamidotriazole. Brain Research Bulletin. 81: 320-6. PMID 19679174 DOI: 10.1016/J.Brainresbull.2009.08.001  0.444
2010 Bhatwadekar A, Stepps V, Grant MB, Bartelmez SH. Differential Expression of Transforming Growth Factor Beta Receptor 2 (TGFβR2) In Diabetic CD34+ Cells: Implications for Vascular Repair Blood. 116: 4795-4795. DOI: 10.1182/Blood.V116.21.4795.4795  0.372
2010 Jarajapu YP, Caballero S, Liu L, Shenoy V, Katovich MJ, Raizada MK, Grant MB. Activation of the Protective Arm of Renin Angiotensin System (RAS) Corrects the Reparative Dysfunction of Diabetic CD34+ Cells. Blood. 116: 2637-2637. DOI: 10.1182/Blood.V116.21.2637.2637  0.415
2010 Hazra S, Jarajapu YP, Liu L, Caballero S, Stepps V, Bhatwadekar A, Boulton ME, Higgins PJ, Bartelmez SH, Grant MB. Inhibition of Plasminogen Activator Inhibitor (PAI)-1 Corrects Diabetic CD34+ Dysfunction. Blood. 116: 1601-1601. DOI: 10.1182/Blood.V116.21.1601.1601  0.747
2010 Sengupta N, Caballero S, Moldovan N, Grant MB. Stem and progenitor cells in the retina Frontiers in Diabetes. 20: 174-193. DOI: 10.1159/000262669  0.803
2009 Sengupta N, Caballero S, Sullivan SM, Chang LJ, Afzal A, Li Calzi S, Kielczewski JL, Prabarakan S, Ellis EA, Moldovan L, Moldovan NI, Boulton ME, Grant MB. Regulation of Adult Hematopoietic Stem Cells Fate for Enhanced Tissue-specific Repair. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1594-1604. PMID 28178547 DOI: 10.1038/mt.2009.145  0.802
2009 Sengupta N, Caballero S, Sullivan SM, Chang LJ, Afzal A, Calzi SL, Kielczewski JL, Prabarakan S, Ellis EA, Moldovan L, Moldovan NI, Boulton ME, Grant MB. Erratum: "Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair" (Molecular Theraphy (2009) 10.1038/mt.2009.145) Molecular Therapy. 17. PMID 28160916 DOI: 10.1038/Mt.2009.180  0.774
2009 Busik JV, Tikhonenko M, Bhatwadekar A, Opreanu M, Yakubova N, Caballero S, Player D, Nakagawa T, Afzal A, Kielczewski J, Sochacki A, Hasty S, Li Calzi S, Kim S, Duclas SK, ... ... Grant MB, et al. Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock. The Journal of Experimental Medicine. 206: 2897-906. PMID 19934019 DOI: 10.1084/Jem.20090889  0.772
2009 Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, ... ... Grant MB, et al. Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circulation Research. 105: 897-905. PMID 19762684 DOI: 10.1161/Circresaha.109.199059  0.763
2009 Chen B, Caballero S, Seo S, Grant MB, Lewin AS. Delivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature. Investigative Ophthalmology & Visual Science. 50: 5587-95. PMID 19628743 DOI: 10.1167/Iovs.09-3633  0.333
2009 Sengupta N, Caballero S, Sullivan SM, Chang LJ, Afzal A, Li Calzi S, Kielczewski JL, Prabarakan S, Ellis EA, Moldovan L, Moldovan NI, Boulton ME, Grant MB, Scott EW, Harris JR. Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1594-604. PMID 19584817 DOI: 10.1038/Mt.2009.145  0.801
2009 Bhatwadekar AD, Glenn JV, Curtis TM, Grant MB, Stitt AW, Gardiner TA. Retinal endothelial cell apoptosis stimulates recruitment of endothelial progenitor cells. Investigative Ophthalmology & Visual Science. 50: 4967-73. PMID 19474402 DOI: 10.1167/Iovs.09-3616  0.505
2009 Li Calzi S, Kent DL, Chang KH, Padgett KR, Afzal A, Chandra SB, Caballero S, English D, Garlington W, Hiscott PS, Sheridan CM, Grant MB, Forder JR. Labeling of stem cells with monocrystalline iron oxide for tracking and localization by magnetic resonance imaging. Microvascular Research. 78: 132-9. PMID 19345699 DOI: 10.1016/J.Mvr.2009.03.007  0.378
2009 Kosugi T, Heinig M, Nakayama T, Connor T, Yuzawa Y, Li Q, Hauswirth WW, Grant MB, Croker BP, Campbell-Thompson M, Zhang L, Atkinson MA, Segal MS, Nakagawa T. Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice. The American Journal of Pathology. 174: 1221-9. PMID 19246639 DOI: 10.2353/Ajpath.2009.080605  0.366
2009 Caballero S, Swaney J, Moreno K, Afzal A, Kielczewski J, Stoller G, Cavalli A, Garland W, Hansen G, Sabbadini R, Grant MB. Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization. Experimental Eye Research. 88: 367-77. PMID 18723015 DOI: 10.1016/J.Exer.2008.07.012  0.756
2009 Bartelmez S, Bhatwadekar A, Iversen P, Ruscetti FW, Grant M. Transient Inhibition of Transforming Growth Factor-β1 in Human Blood-Derived CD34+ Cells Enhances Survival and Proliferation in Vitro and Vascular Reparative functions In Vivo. Blood. 114: 3546-3546. DOI: 10.1182/Blood.V114.22.3546.3546  0.402
2008 Kramerov AA, Saghizadeh M, Caballero S, Shaw LC, Li Calzi S, Bretner M, Montenarh M, Pinna LA, Grant MB, Ljubimov AV. Inhibition of protein kinase CK2 suppresses angiogenesis and hematopoietic stem cell recruitment to retinal neovascularization sites Molecular and Cellular Biochemistry. 316: 177-186. PMID 18612802 DOI: 10.1007/S11010-008-9831-4  0.44
2008 Sato W, Kosugi T, Zhang L, Roncal CA, Heinig M, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Grant MB, Croker BP, Nakagawa T. The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 949-61. PMID 18607348 DOI: 10.1038/Labinvest.2008.60  0.446
2008 Li Calzi S, Purich DL, Chang KH, Afzal A, Nakagawa T, Busik JV, Agarwal A, Segal MS, Grant MB. Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetes. Diabetes. 57: 2488-94. PMID 18559661 DOI: 10.2337/Db08-0381  0.321
2008 Busik JV, Mohr S, Grant MB. Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators. Diabetes. 57: 1952-65. PMID 18420487 DOI: 10.2337/Db07-1520  0.366
2008 Diao Y, Guthrie S, Xia SL, Ouyang X, Zhang L, Xue J, Lee P, Grant M, Scott E, Segal MS. Long-term engraftment of bone marrow-derived cells in the intimal hyperplasia lesion of autologous vein grafts. The American Journal of Pathology. 172: 839-48. PMID 18276778 DOI: 10.2353/Ajpath.2008.070840  0.335
2008 Guerin E, Sheridan C, Assheton D, Kent D, Wong D, Grant M, Hiscott P. SDF1-alpha is associated with VEGFR-2 in human choroidal neovascularisation. Microvascular Research. 75: 302-307. PMID 18234239 DOI: 10.1016/J.Mvr.2007.12.001  0.432
2008 Grant MB, Boulton ME, Ljubimov AV. Erythropoietin: when liability becomes asset in neurovascular repair. The Journal of Clinical Investigation. 118: 467-70. PMID 18219388 DOI: 10.1172/Jci34643  0.365
2008 Boulton ME, Cai J, Grant MB, Zhang Y. Gamma-secretase regulates VEGFR-1 signalling in vascular endothelium and RPE. Advances in Experimental Medicine and Biology. 613: 313-9. PMID 18188959 DOI: 10.1007/978-0-387-74904-4_36  0.423
2008 Santulli RJ, Kinney WA, Ghosh S, Decorte BL, Liu L, Tuman RW, Zhou Z, Huebert N, Bursell SE, Clermont AC, Grant MB, Shaw LC, Mousa SA, Galemmo RA, Johnson DL, et al. Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats. The Journal of Pharmacology and Experimental Therapeutics. 324: 894-901. PMID 18083913 DOI: 10.1124/Jpet.107.131656  0.396
2008 Jarajapu YP, Guberski DL, Grant MB, Knot HJ. Myogenic tone and reactivity of cerebral arteries in type II diabetic BBZDR/Wor rat. European Journal of Pharmacology. 579: 298-307. PMID 18036520 DOI: 10.1016/J.Ejphar.2007.10.028  0.368
2008 Bartelmez S, Ruscetti FW, Iversen P, Bhatwadekar A, Grant M. Accelerated Repair of Vascular Injury in Diabetes by TGF-β1 Modified Hematopoietic Stem Cells (HSC). Blood. 112: 1398-1398. DOI: 10.1182/Blood.V112.11.1398.1398  0.468
2007 Afzal A, Shaw LC, Ljubimov AV, Boulton ME, Segal MS, Grant MB. Retinal and choroidal microangiopathies: therapeutic opportunities. Microvascular Research. 74: 131-44. PMID 17585951 DOI: 10.1016/J.Mvr.2007.04.011  0.372
2007 Chang KH, Chan-Ling T, McFarland EL, Afzal A, Pan H, Baxter LC, Shaw LC, Caballero S, Sengupta N, Li Calzi S, Sullivan SM, Grant MB. IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development. Proceedings of the National Academy of Sciences of the United States of America. 104: 10595-600. PMID 17567755 DOI: 10.1073/Pnas.0702072104  0.817
2007 Lu SJ, Feng Q, Caballero S, Chen Y, Moore MA, Grant MB, Lanza R. Generation of functional hemangioblasts from human embryonic stem cells. Nature Methods. 4: 501-9. PMID 17486087 DOI: 10.1038/Nmeth1041  0.481
2007 Kornberg LJ, Grant MB. Adenoviruses increase endothelial cell proliferation, migration, and tube formation: partial reversal by the focal adhesion kinase inhibitor, FRNK. Microvascular Research. 73: 157-62. PMID 17407784 DOI: 10.1016/J.Mvr.2007.02.005  0.372
2007 Caballero S, Sengupta N, Afzal A, Chang KH, Li Calzi S, Guberski DL, Kern TS, Grant MB. Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes. 56: 960-7. PMID 17395742 DOI: 10.2337/Db06-1254  0.817
2007 Deshane J, Chen S, Caballero S, Grochot-Przeczek A, Was H, Li Calzi S, Lach R, Hock TD, Chen B, Hill-Kapturczak N, Siegal GP, Dulak J, Jozkowicz A, Grant MB, Agarwal A. Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism. The Journal of Experimental Medicine. 204: 605-18. PMID 17339405 DOI: 10.1084/Jem.20061609  0.458
2007 Palii SS, Caballero S, Shapiro G, Grant MB. Medical treatment of diabetic retinopathy with somatostatin analogues. Expert Opinion On Investigational Drugs. 16: 73-82. PMID 17155855 DOI: 10.1517/13543784.16.1.73  0.394
2007 Ellis E, Guberski D, Grant M. Cytochemical Localization of Sites of Superoxide and Hydrogen Peroxide Production in Diabetic and Non-diabetic Kidneys Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607072613  0.332
2007 Sengupta N, Grant MB, Caballero S, Boulton ME. Hematopoietic stem cells in vascular development and ocular neovascularization Retinal Vascular Disease. 78-96. DOI: 10.1007/978-3-540-29542-6_4  0.781
2006 Neu J, Afzal A, Pan H, Gallego E, Li N, Li Calzi S, Caballero S, Spoerri PE, Shaw LC, Grant MB. The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy. Investigative Ophthalmology & Visual Science. 47: 3151-5. PMID 16799062 DOI: 10.1167/Iovs.05-1473  0.413
2006 Kramerov AA, Saghizadeh M, Pan H, Kabosova A, Montenarh M, Ahmed K, Penn JS, Chan CK, Hinton DR, Grant MB, Ljubimov AV. Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. The American Journal of Pathology. 168: 1722-36. PMID 16651637 DOI: 10.2353/Ajpath.2006.050533  0.384
2006 Harris JR, Brown GA, Jorgensen M, Kaushal S, Ellis EA, Grant MB, Scott EW. Bone marrow-derived cells home to and regenerate retinal pigment epithelium after injury. Investigative Ophthalmology & Visual Science. 47: 2108-13. PMID 16639022 DOI: 10.1167/Iovs.05-0928  0.408
2006 Chan-Ling T, Baxter L, Afzal A, Sengupta N, Caballero S, Rosinova E, Grant MB. Hematopoietic stem cells provide repair functions after laser-induced Bruch's membrane rupture model of choroidal neovascularization. The American Journal of Pathology. 168: 1031-44. PMID 16507916 DOI: 10.2353/Ajpath.2006.050697  0.81
2006 Spoerri PE, Afzal A, Li Calzi S, Shaw LC, Cai J, Pan H, Boulton M, Grant MB. Effects of VEGFR-1, VEGFR-2, and IGF-IR hammerhead ribozymes on glucose-mediated tight junction expression in cultured human retinal endothelial cells. Molecular Vision. 12: 32-42. PMID 16446700  0.307
2006 Shaw LC, Pan H, Afzal A, Calzi SL, Spoerri PE, Sullivan SM, Grant MB. Proliferating endothelial cell-specific expression of IGF-I receptor ribozyme inhibits retinal neovascularization Gene Therapy. 13: 752-760. PMID 16437130 DOI: 10.1038/Sj.Gt.3302718  0.467
2006 Segal MS, Shah R, Afzal A, Perrault CM, Chang K, Schuler A, Beem E, Shaw LC, Li Calzi S, Harrison JK, Tran-Son-Tay R, Grant MB. Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes. Diabetes. 55: 102-9. PMID 16380482 DOI: 10.2337/Diabetes.55.01.06.Db05-0803  0.49
2006 Cai J, Jiang WG, Grant MB, Boulton M. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. The Journal of Biological Chemistry. 281: 3604-13. PMID 16339148 DOI: 10.1074/Jbc.M507401200  0.403
2006 Villegas LR, Sullivan S, Grant M. 927. Development of Non-Viral Gene Therapy Targeting Insulin-Like Growth Factor (IGF) System for Treatment of Brain Tumors Molecular Therapy. 13: S358. DOI: 10.1016/J.Ymthe.2006.08.1018  0.301
2005 Ellis EA, Sengupta N, Caballero S, Guthrie SM, Mames RN, Grant MB. Nitric oxide synthases modulate progenitor and resident endothelial cell behavior in galactosemia. Antioxidants & Redox Signaling. 7: 1413-22. PMID 16356104 DOI: 10.1089/Ars.2005.7.1413  0.787
2005 Grant MB, Caballero S. The potential role of octreotide in the treatment of diabetic retinopathy. Treatments in Endocrinology. 4: 199-203. PMID 16053337 DOI: 10.2165/00024677-200504040-00001  0.428
2005 Ljubimov AV, Grant MB. P450 in the angiogenesis affair: the unusual suspect. The American Journal of Pathology. 166: 341-4. PMID 15681818 DOI: 10.1016/S0002-9440(10)62257-2  0.405
2005 Butler JM, Guthrie SM, Koc M, Afzal A, Caballero S, Brooks HL, Mames RN, Segal MS, Grant MB, Scott EW. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. The Journal of Clinical Investigation. 115: 86-93. PMID 15630447 DOI: 10.1172/Jci22869  0.539
2005 Sengupta N, Caballero S, Mames RN, Timmers AM, Saban D, Grant MB. Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors. Investigative Ophthalmology & Visual Science. 46: 343-8. PMID 15623794 DOI: 10.1167/Iovs.04-0153  0.809
2005 Guthrie SM, Curtis LM, Mames RN, Simon GG, Grant MB, Scott EW. The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells. Blood. 105: 1916-22. PMID 15546953 DOI: 10.1182/Blood-2004-09-3415  0.444
2005 Guthrie SM, Caballero S, Mames RN, Grant MB, Scott EW. Analysis of the vascular potential of hematopoietic stem cells. Methods in Molecular Medicine. 105: 369-80. PMID 15492408 DOI: 10.1385/1-59259-826-9:369  0.421
2005 Ellis EA, Grant MB. Lack of Vascular Nitric Oxide Results in Basement Membrane Thickening in Galactose Induced Diabetic Retinopathy Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605501612  0.386
2004 Brooks HL, Caballero S, Newell CK, Steinmetz RL, Watson D, Segal MS, Harrison JK, Scott EW, Grant MB. Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinolone. Archives of Ophthalmology. 122: 1801-7. PMID 15596583 DOI: 10.1001/Archopht.122.12.1801  0.457
2004 Ljubimov AV, Caballero S, Aoki AM, Pinna LA, Grant MB, Castellon R. Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization. Investigative Ophthalmology & Visual Science. 45: 4583-91. PMID 15557471 DOI: 10.1167/Iovs.04-0686  0.407
2004 Kornberg LJ, Shaw LC, Spoerri PE, Caballero S, Grant MB. Focal adhesion kinase overexpression induces enhanced pathological retinal angiogenesis Investigative Ophthalmology and Visual Science. 45: 4463-4469. PMID 15557455 DOI: 10.1167/Iovs.03-1201  0.405
2004 Grant MB, Afzal A, Spoerri P, Pan H, Shaw LC, Mames RN. The role of growth factors in the pathogenesis of diabetic retinopathy Expert Opinion On Investigational Drugs. 13: 1275-1293. PMID 15461557 DOI: 10.1517/13543784.13.10.1275  0.44
2004 Pan H, Nguyen NQN, Yoshida H, Bentzien F, Shaw LC, Rentier-Delrue F, Martial JA, Weiner R, Struman I, Grant MB. Molecular targeting of antiangiogenic factor 16K hPRL inhibits oxygen-induced retinopathy in mice Investigative Ophthalmology and Visual Science. 45: 2413-2419. PMID 15223825 DOI: 10.1167/Iovs.03-1001  0.313
2004 Shaw LC, Grant MB. Insulin like growth factor-1 and insulin-like growth factor binding proteins: Their possible roles in both maintaining normal retinal vascular function and in promoting retinal pathology Reviews in Endocrine and Metabolic Disorders. 5: 199-207. PMID 15211091 DOI: 10.1023/B:Remd.0000032408.18015.B1  0.361
2004 Caballero S, Sengupta N, Crafoord S, Lund R, Kruse FE, Young M, Grant MB. The many possible roles of stem cells in age-related macular degeneration Graefe's Archive For Clinical and Experimental Ophthalmology. 242: 85-90. PMID 14685872 DOI: 10.1007/S00417-003-0813-7  0.775
2004 Ellis EA, Littleton RL, Grant MB. Decreased NADH Oxidase in Galactose Induced Diabetic Retinopathy in Female as Compared to Male C57BL/6J Mice Microscopy and Microanalysis. 10: 202-203. DOI: 10.1017/S1431927604881728  0.338
2003 Chen W, Jump DB, Grant MB, Esselman WJ, Busik JV. Dyslipidemia, but not hyperglycemia, induces inflammatory adhesion molecules in human retinal vascular endothelial cells. Investigative Ophthalmology & Visual Science. 44: 5016-22. PMID 14578429 DOI: 10.1167/Iovs.03-0418  0.484
2003 Sengupta N, Caballero S, Mames RN, Butler JM, Scott EW, Grant MB. The role of adult bone marrow-derived stem cells in choroidal neovascularization. Investigative Ophthalmology & Visual Science. 44: 4908-13. PMID 14578416 DOI: 10.1167/Iovs.03-0342  0.79
2003 Shaw LC, Afzal A, Lewin AS, Timmers AM, Spoerri PE, Grant MB. Decreased expression of the insulin-like growth factor 1 receptor by ribozyme cleavage Investigative Ophthalmology and Visual Science. 44: 4105-4113. PMID 12939334 DOI: 10.1167/Iovs.03-0295  0.315
2003 Afzal A, Shaw LC, Caballero S, Spoerri PE, Lewin AS, Zeng D, Belardinelli L, Grant MB. Reduction in preretinal neovascularization by ribozymes that cleave the A2B adenosine receptor mRNA Circulation Research. 93: 500-506. PMID 12919950 DOI: 10.1161/01.Res.0000091260.78959.Bc  0.342
2003 Grant MB, Caballero S, Brown GA, Guthrie SM, Mames RN, Vaught T, Scott EW. The contribution of adult hematopoietic stem cells to retinal neovascularization. Advances in Experimental Medicine and Biology. 522: 37-45. PMID 12674209 DOI: 10.1007/978-1-4615-0169-5_5  0.494
2003 Wilson SH, Ljubimov AV, Morla AO, Caballero S, Shaw LC, Spoerri PE, Tarnuzzer RW, Grant MB. Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through α5β1 integrin and PI 3-kinase Investigative Ophthalmology and Visual Science. 44: 1704-1715. PMID 12657612 DOI: 10.1167/Iovs.02-0773  0.343
2003 Grant MB, Caballero S. Somatostatin analogues as drug therapies for retinopathies. Drugs of Today (Barcelona, Spain : 1998). 38: 783-91. PMID 12582462 DOI: 10.1358/Dot.2002.38.11.820138  0.485
2003 Spoerri PE, Caballero S, Wilson SH, Shaw LC, Grant MB. Expression of IGFBP-3 by human retinal endothelial cell cultures: IGFBP-3 involvement in growth inhibition and apoptosis Investigative Ophthalmology and Visual Science. 44: 365-369. PMID 12506097 DOI: 10.1167/Iovs.02-0309  0.402
2003 Ann Ellis E, Guy JR, Grant MB. Correlative Imaging in the Study of Oxidative Stress in Two Animal Models: Experimental Allergic Encephalomyelitis and Diabetic Retinopathy Microscopy and Microanalysis. 9: 1548-1549. DOI: 10.1017/S1431927603447740  0.312
2002 Fritz JJ, Lewin A, Hauswirth W, Agarwal A, Grant M, Shaw L. Development of hammerhead ribozymes to modulate endogenous gene expression for functional studies. Methods (San Diego, Calif.). 28: 276-85. PMID 12413427 DOI: 10.1016/S1046-2023(02)00233-5  0.3
2002 Castellon R, Caballero S, Hamdi HK, Atilano SR, Aoki AM, Tarnuzzer RW, Kenney MC, Grant MB, Ljubimov AV. Effects of tenascin-C on normal and diabetic retinal endothelial cells in culture. Investigative Ophthalmology & Visual Science. 43: 2758-66. PMID 12147613  0.346
2002 Raisler BJ, Berns KI, Grant MB, Beliaev D, Hauswirth WW. Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization. Proceedings of the National Academy of Sciences of the United States of America. 99: 8909-14. PMID 12072560 DOI: 10.1073/Pnas.122247299  0.441
2002 McGarry MA, Charles GD, Medrano T, Bubb MR, Grant MB, Campbell-Thompson M, Shiverick KT. Benzo(a)pyrene, but not 2,3,7,8-tetrachlorodibenzo-p-dioxin, alters cell adhesion proteins in human uterine RL95-2 cells. Biochemical and Biophysical Research Communications. 294: 101-7. PMID 12054747 DOI: 10.1016/S0006-291X(02)00437-0  0.37
2002 Grant MB, May WS, Caballero S, Brown GA, Guthrie SM, Mames RN, Byrne BJ, Vaught T, Spoerri PE, Peck AB, Scott EW. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nature Medicine. 8: 607-12. PMID 12042812 DOI: 10.1038/Nm0602-607  0.445
2002 Ellis EA, Guberski DL, Hutson B, Grant MB. Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat. Nitric Oxide : Biology and Chemistry. 6: 295-304. PMID 12009847 DOI: 10.1006/Niox.2001.0419  0.408
2001 Wilson SH, Davis MI, Caballero S, Grant MB. Modulation of retinal endothelial cell behaviour by insulin-like growth factor I and somatostatin analogues: implications for diabetic retinopathy. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 11: S53-9. PMID 11527089 DOI: 10.1016/S1096-6374(01)80009-5  0.425
2001 Davis MI, Wilson SH, Grant MB. The therapeutic problem of proliferative diabetic retinopathy: targeting somatostatin receptors. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 33: 295-9. PMID 11440276 DOI: 10.1055/S-2001-15286  0.438
2001 Grant M, Mames R, Fitzgerald C, Hazariwala K, Cooper-DeHoff R, Caballero S, Estes K. Efficacy of Octreotide in the Therapy of Severe Nonproliferative and Early Proliferative Diabetic Retinopathy: A Randomized Controlled Study: Response to Gehrs Diabetes Care. 24: 182-183. DOI: 10.2337/Diacare.24.1.182-A  0.335
2001 Ellis EA, Grant MB. Oxidative Stress in Galactose Induced Diabetic Retinopathy in Inducible Nitric Oxide Synthase Knockout Mice Microscopy and Microanalysis. 7: 638-639. DOI: 10.1017/S1431927600029263  0.331
2000 Spoerri PE, Ellis EA, Tarnuzzer RW, Grant MB. Insulin-like growth factor: receptor and binding proteins in human retinal endothelial cell cultures of diabetic and non-diabetic origin. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 8: 125-32. PMID 10987679 DOI: 10.1016/S1096-6374(98)80102-0  0.4
2000 Grant MB, Mames RN, Fitzgerald C, Hazariwala KM, Cooper-DeHoff R, Caballero S, Estes KS. The efficacy of octreotide in the therapy of severe nonproliferative and early proliferative diabetic retinopathy: a randomized controlled study. Diabetes Care. 23: 504-9. PMID 10857943 DOI: 10.2337/Diacare.23.4.504  0.39
2000 Ellis EA, Guberski DL, Somogyi-Mann M, Grant MB. Increased H2O2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat. Free Radical Biology & Medicine. 28: 91-101. PMID 10656295 DOI: 10.1016/S0891-5849(99)00216-6  0.39
2000 Ellis EA, Guberski DL, Grant MB, Armstrong D. Oxidative Stress and Lipid Peroxides in the Retina of the BBZ/WOR Diabetic Rat: An Ultrastructural Cytochemical Study Microscopy and Microanalysis. 6: 336-337. DOI: 10.1017/S1431927600034176  0.319
1999 Grant MB, Tarnuzzer RW, Caballero S, Ozeck MJ, Davis MI, Spoerri PE, Feoktistov I, Biaggioni I, Shryock JC, Belardinelli L. Adenosine receptor activation induces vascular endothelial growth factor in human retinal endothelial cells. Circulation Research. 85: 699-706. PMID 10521243 DOI: 10.1161/01.Res.85.8.699  0.385
1999 Charles GD, Grant MB, Medrano TA, Saunders P, Edery M, Kelly PA, Shiverick KT. Endothelial cell chemotaxic activity expressed in rat placenta is not associated with prolactin-like proteins B and C. Life Sciences. 65: 795-804. PMID 10466745 DOI: 10.1016/S0024-3205(99)00306-9  0.306
1999 Ellis EA, Grant MB, Guberski DL. Oxidative Injury by Oxygen and Nitrogen Radicals in Diabetic Retinopathy in the BBZ/WOR Rat: CytoChemical and ImmunoCytochemical Studies Microscopy and Microanalysis. 5: 482-483. DOI: 10.1017/S1431927600015737  0.317
1998 Grant MB, Caballero S, Bush DM, Spoerri PE. Fibronectin fragments modulate human retinal capillary cell proliferation and migration. Diabetes. 47: 1335-40. PMID 9703336 DOI: 10.2337/Diab.47.8.1335  0.392
1998 Grant MB, Caballero S, Tarnuzzer RW, Bass KE, Ljubimov AV, Spoerri PE, Galardy RE. Matrix metalloproteinase expression in human retinal microvascular cells Diabetes. 47: 1311-1317. PMID 9703333 DOI: 10.2337/Diab.47.8.1311  0.319
1998 Ellis EA, Grant MB, Murray FT, Wachowski MB, Guberski DL, Kubilis PS, Lutty GA. Increased NADH oxidase activity in the retina of the BBZ/Wor diabetic rat. Free Radical Biology & Medicine. 24: 111-20. PMID 9436620 DOI: 10.1016/S0891-5849(97)00202-5  0.427
1998 Ellis EA, Grant MB, Guberski DL. Nitric Oxide Synthase in Diabetic Retinopathy in the BBZ/WOR Rat: An Immunocytochemical Study Microscopy and Microanalysis. 4: 1074-1075. DOI: 10.1017/S1431927600025496  0.338
1997 Spoerri PE, Grant MB, Gomez J, Vernadakis A. Endothelial cell conditioned media mediated regulation of glutamine synthetase activity in glial cells. Brain Research. Developmental Brain Research. 104: 205-8. PMID 9466724 DOI: 10.1016/S0165-3806(97)00173-9  0.32
1996 Grant MB, Ellis EA, Caballero S, Mames RN. Plasminogen activator inhibitor-1 overexpression in nonproliferative diabetic retinopathy. Experimental Eye Research. 63: 233-44. PMID 8943696 DOI: 10.1006/Exer.1996.0112  0.432
1995 Munjal ID, McLean NV, Grant MB, Blake DA. Differences in the Synthesis of Secreted Proteins in Human Retinal Endothelial Cells of Diabetic and Nondiabetic Origin Retina. 15: 174. DOI: 10.1097/00006982-199515020-00020  0.361
1994 Munjal ID, Mclean NV, Grant MB, Blake DA. Differences in the synthesis of secreted proteins in human retinal endothelial cells of diabetic and nondiabetic origin Current Eye Research. 13: 303-310. PMID 8033591 DOI: 10.3109/02713689408995792  0.467
1993 Grant MB, Mames RN, Fitzgerald C, Ellis EA, Aboufriekha M, Guy J. Insulin-like growth factor I acts as an angiogenic agent in rabbit cornea and retina: comparative studies with basic fibroblast growth factor. Diabetologia. 36: 282-91. PMID 7682976 DOI: 10.1007/Bf00400229  0.344
1993 Grant MB, Caballero S, Millard WJ. Inhibition of IGF-I and b-FGF stimulated growth of human retinal endothelial cells by the somatostatin analogue, octreotide: a potential treatment for ocular neovascularization. Regulatory Peptides. 48: 267-78. PMID 7505469 DOI: 10.1016/0167-0115(93)90356-D  0.389
1991 Schultz GS, Grant MB. Neovascular growth factors. Eye (London, England). 170-80. PMID 1712736 DOI: 10.1038/eye.1991.31  0.302
1990 Grant MB, Guay C, Marsh R. Insulin-like growth factor I stimulates proliferation, migration, and plasminogen activator release by human retinal pigment epithelial cells. Current Eye Research. 9: 323-35. PMID 2111235 DOI: 10.3109/02713689008999620  0.38
1989 Grant MB, Fitzgerald C, Guay C, Lottenberg R. Fibrinolytic capacity following stimulation with desmopressin acetate in patients with diabetes mellitus. Metabolism: Clinical and Experimental. 38: 901-7. PMID 2505017 DOI: 10.1016/0026-0495(89)90239-4  0.326
1987 Grant M, Jerdan J, Merimee TJ. Insulin-like growth factor-I modulates endothelial cell chemotaxis. The Journal of Clinical Endocrinology and Metabolism. 65: 370-371. PMID 3597713 DOI: 10.1210/Jcem-65-2-370  0.331
1987 Misbin RI, Grant MB, Pecker MS, Atlas SA. Elevated levels of plasma prorenin (inactive renin) in diabetic and nondiabetic patients with autonomic dysfunction. The Journal of Clinical Endocrinology and Metabolism. 64: 964-8. PMID 3549762 DOI: 10.1210/Jcem-64-5-964  0.312
1986 Grant M, Russell B, Fitzgerald C, Merimee TJ. Insulin-like growth factors in vitreous. Studies in control and diabetic subjects with neovascularization. Diabetes. 35: 416-20. PMID 2420665 DOI: 10.2337/Diab.35.4.416  0.362
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