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Billy W. Day - Publications

Affiliations: 
Pharmaceutical Sciences University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Drug Discovery
Website:
http://www.pitt.edu/~bday/bday.html

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pritchard KA, Jing X, Teng M, Wells C, Jia S, Afolayan AJ, Jarzembowski J, Day BW, Naylor S, Hessner MJ, Konduri GG, Teng RJ. Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia. Plos One. 17: e0269564. PMID 36018859 DOI: 10.1371/journal.pone.0269564  0.229
2022 Pritchard KA Jr, Jing X, Teng M, Wells C, Jia S, Afolayan AJ, Jarzembowski J, Day BW, Naylor S, Hessner MJ, Konduri GG, Teng RJ. Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia. Plos One. 17: e0269564. PMID 36018859  0.229
2022 Sabbioni G, Day BW. Quo vadis blood protein adductomics? Archives of Toxicology. 96: 79-103. PMID 34773488 DOI: 10.1007/s00204-021-03165-2  0.255
2021 Teng RJ, Jing X, Martin DP, Hogg N, Haefke A, Konduri GG, Day BW, Naylor S, Pritchard KA. N-Acetyl-Lysyltyrosylcysteine Amide, a Novel Systems Pharmacology Agent, Reduces Bronchopulmonary Dysplasia in Hyperoxic Neonatal Rat Pups. Free Radical Biology & Medicine. PMID 33607217 DOI: 10.1016/j.freeradbiomed.2021.02.006  0.294
2020 Sabbioni G, Berset JD, Day BW. Is It Realistic to Propose Determination of a Lifetime Internal Exposome? Chemical Research in Toxicology. PMID 32672951 DOI: 10.1021/Acs.Chemrestox.0C00092  0.355
2020 Sabbioni G, Day BW. Prioritizing aromatic amines for biomonitoring studies. Chemico-Biological Interactions. 109191. PMID 32649936 DOI: 10.1016/J.Cbi.2020.109191  0.388
2017 Kaltenmeier CT, Vollmer LL, Vernetti LA, Caprio L, Davis K, Korotchenko VN, Day BW, Tsang M, Hulkower KI, Lotze MT, Vogt A. A tumor cell-selective inhibitor of mitogen-activated protein kinase phosphatases sensitizes breast cancer cells to lymphokine-activated killer cell activity. The Journal of Pharmacology and Experimental Therapeutics. PMID 28154014 DOI: 10.1124/Jpet.116.239756  0.754
2016 Colombo R, Wang Z, Han J, Balachandran R, Daghestani HN, Camarco DP, Vogt A, Day BW, Mendel D, Wipf P. Total Synthesis and Biological Evaluation of Tubulysin Analogs. The Journal of Organic Chemistry. PMID 27447195 DOI: 10.1021/Acs.Joc.6B01314  0.822
2016 Emert-Sedlak LA, Loughran HM, Shi H, Kulp JL, Shu ST, Zhao J, Day BW, Wrobel JE, Reitz AB, Smithgall TE. Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists. Bioorganic & Medicinal Chemistry Letters. 26: 1480-4. PMID 26852364 DOI: 10.1016/J.Bmcl.2016.01.043  0.786
2015 Liu H, Li W, Rose ME, Hickey RW, Chen J, Uechi GT, Balasubramani M, Day BW, Patel KV, Graham SH. The point mutation UCH-L1 C152A protects primary neurons against cyclopentenone prostaglandin-induced cytotoxicity: implications for post-ischemic neuronal injury. Cell Death & Disease. 6: e1966. PMID 26539913 DOI: 10.1038/Cddis.2015.323  0.362
2015 Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, ... ... Day BW, et al. N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia. European Journal of Medicinal Chemistry. 96: 504-18. PMID 25951294 DOI: 10.1016/J.Ejmech.2015.02.041  0.814
2014 Smith SE, Dello Buono MC, Carper DJ, Coleman RS, Day BW. Structure elucidation of phase I metabolites of the microtubule perturbagens: ceratamines A and B. Journal of Natural Products. 77: 1572-8. PMID 24964362 DOI: 10.1021/Np4010882  0.43
2014 Korotchenko VN, Saydmohammed M, Vollmer LL, Bakan A, Sheetz K, Debiec KT, Greene KA, Agliori CS, Bahar I, Day BW, Vogt A, Tsang M. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem : a European Journal of Chemical Biology. 15: 1436-45. PMID 24909879 DOI: 10.1002/Cbic.201402000  0.767
2014 Gallo MB, Falso MJ, Balem F, Menezes D, Rocha N, Balachandran R, Sturgeon TS, Pupo MT, Day BW. The anti-promyelocytic leukemia mode of action of two endophytic secondary metabolites unveiled by a proteomic approach. Planta Medica. 80: 473-81. PMID 24710897 DOI: 10.1055/S-0034-1368301  0.792
2014 Wang W, Mohsen AW, Uechi G, Schreiber E, Balasubramani M, Day B, Michael Barmada M, Vockley J. Complex changes in the liver mitochondrial proteome of short chain acyl-CoA dehydrogenase deficient mice Molecular Genetics and Metabolism. 112: 30-39. PMID 24685553 DOI: 10.1016/J.Ymgme.2014.02.014  0.761
2014 Iyer PC, Zhao J, Emert-Sedlak LA, Moore KK, Smithgall TE, Day BW. Synthesis and structure-activity analysis of diphenylpyrazolodiazene inhibitors of the HIV-1 Nef virulence factor. Bioorganic & Medicinal Chemistry Letters. 24: 1702-6. PMID 24650642 DOI: 10.1016/J.Bmcl.2014.02.045  0.798
2014 Alshogran OY, Ocque AJ, Zhao J, Day BW, Leblond FA, Pichette V, Nolin TD. Determination of warfarin alcohols by ultra-high performance liquid chromatography-tandem mass spectrometry: application to in vitro enzyme kinetic studies. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 944: 63-8. PMID 24291722 DOI: 10.1016/J.Jchromb.2013.11.014  0.762
2014 Vollmer L, Vernetti L, Bakan A, Korotchenko V, Bahar I, Day B, Tsang M, Vogt A. Abstract 745: A non-redox reactive allosteric inhibitor of MAPK phosphatases with selective toxicity to human cancer cells Cancer Research. 74: 745-745. DOI: 10.1158/1538-7445.Am2014-745  0.774
2013 Trible RP, Narute P, Emert-Sedlak LA, Alvarado JJ, Atkins K, Thomas L, Kodama T, Yanamala N, Korotchenko V, Day BW, Thomas G, Smithgall TE. Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology. 10: 135. PMID 24229420 DOI: 10.1186/1742-4690-10-135  0.747
2013 Cianciolo Cosentino C, Skrypnyk NI, Brilli LL, Chiba T, Novitskaya T, Woods C, West J, Korotchenko VN, McDermott L, Day BW, Davidson AJ, Harris RC, de Caestecker MP, Hukriede NA. Histone deacetylase inhibitor enhances recovery after AKI. Journal of the American Society of Nephrology : Jasn. 24: 943-53. PMID 23620402 DOI: 10.1681/Asn.2012111055  0.739
2013 Tao L, Day BW, Hu B, Xiang YB, Wang R, Stern MC, Gago-Dominguez M, Cortessis VK, Conti DV, Van Den Berg D, Pike MC, Gao YT, Yu MC, Yuan JM. Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 937-45. PMID 23539508 DOI: 10.1158/1055-9965.Epi-12-1447  0.38
2013 Salum LB, Altei WF, Chiaradia LD, Cordeiro MN, Canevarolo RR, Melo CP, Winter E, Mattei B, Daghestani HN, Santos-Silva MC, Creczynski-Pasa TB, Yunes RA, Yunes JA, Andricopulo AD, Day BW, et al. Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors. European Journal of Medicinal Chemistry. 63: 501-10. PMID 23524161 DOI: 10.1016/J.Ejmech.2013.02.037  0.813
2013 Lessa JA, Soares MA, dos Santos RG, Mendes IC, Salum LB, Daghestani HN, Andricopulo AD, Day BW, Vogt A, Beraldo H. Gallium(III) complexes with 2-acetylpyridine-derived thiosemicarbazones: antimicrobial and cytotoxic effects and investigation on the interactions with tubulin. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 26: 151-65. PMID 23344786 DOI: 10.1007/S10534-012-9603-1  0.778
2013 Yalowich JC, Skwarska A, Rabovsky AJ, Zhao Y, Phelps MA, Day BW, Kanagasabai R. Abstract 4481: Myeloperoxidase as a determinant for activity of etoposide (VP-16) and other phenolic and non-phenolic anticancer agents: implications for drug-induced leukemogenesis. Cancer Research. 73: 4481-4481. DOI: 10.1158/1538-7445.Am2013-4481  0.478
2012 Johnston PA, Shinde SN, Hua Y, Shun TY, Lazo JS, Day BW. Development and validation of a high-content screening assay to identify inhibitors of cytoplasmic dynein-mediated transport of glucocorticoid receptor to the nucleus. Assay and Drug Development Technologies. 10: 432-56. PMID 22830992 DOI: 10.1089/Adt.2012.456  0.474
2012 Lakshman MK, Kumar A, Balachandran R, Day BW, Andrei G, Snoeck R, Balzarini J. Synthesis and biological properties of C-2 triazolylinosine derivatives. The Journal of Organic Chemistry. 77: 5870-83. PMID 22758929 DOI: 10.1021/Jo300628Y  0.756
2012 Soares MA, Lessa JA, Mendes IC, Da Silva JG, Dos Santos RG, Salum LB, Daghestani H, Andricopulo AD, Day BW, Vogt A, Pesquero JL, Rocha WR, Beraldo H. N⁴-Phenyl-substituted 2-acetylpyridine thiosemicarbazones: cytotoxicity against human tumor cells, structure-activity relationship studies and investigation on the mechanism of action. Bioorganic & Medicinal Chemistry. 20: 3396-409. PMID 22564383 DOI: 10.1016/J.Bmc.2012.04.027  0.793
2012 Cui Y, Balachandran R, Day BW, Floreancig PE. Synthesis and biological evaluation of neopeltolide and analogs. The Journal of Organic Chemistry. 77: 2225-35. PMID 22329423 DOI: 10.1021/Jo2023685  0.776
2012 Daghestani HN, Zhu G, Johnston PA, Shinde SN, Brodsky JL, Day BW. Characterization of inhibitors of glucocorticoid receptor nuclear translocation: a model of cytoplasmic dynein-mediated cargo transport. Assay and Drug Development Technologies. 10: 46-60. PMID 21919741 DOI: 10.1089/Adt.2010.0367  0.794
2011 Jiménez M, Zhu W, Vogt A, Day BW, Curran DP. Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents. Beilstein Journal of Organic Chemistry. 7: 1372-8. PMID 22043248 DOI: 10.3762/Bjoc.7.161  0.475
2011 Wan S, Wu F, Rech JC, Green ME, Balachandran R, Horne WS, Day BW, Floreancig PE. Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs. Journal of the American Chemical Society. 133: 16668-79. PMID 21902245 DOI: 10.1021/Ja207331M  0.779
2011 Vollmer LL, Jiménez M, Camarco DP, Zhu W, Daghestani HN, Balachandran R, Reese CE, Lazo JS, Hukriede NA, Curran DP, Day BW, Vogt A. A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos. Molecular Cancer Therapeutics. 10: 994-1006. PMID 21490306 DOI: 10.1158/1535-7163.Mct-10-1048  0.832
2011 Balasubramani M, Nakao C, Uechi GT, Cardamone J, Kamath K, Leslie KL, Balachandran R, Wilson L, Day BW, Jordan MA. Characterization and detection of cellular and proteomic alterations in stable stathmin-overexpressing, taxol-resistant BT549 breast cancer cells using offgel IEF/PAGE difference gel electrophoresis. Mutation Research. 722: 154-64. PMID 20816848 DOI: 10.1016/J.Mrgentox.2010.08.019  0.762
2011 Tao L, Day BW, Hu B, Xiang Y, Wang R, Stern MC, Gago-Dominguez M, Cortessis VK, Conti DV, Berg DVD, Pike MC, Gao Y, Yu MC, Yuan J. Abstract 4647: 4-Aminobiphenyl hemoglobin adducts in relation to risk of bladder cancer among lifelong nonsmokers Epidemiology. 71: 4647-4647. DOI: 10.1158/1538-7445.Am2011-4647  0.333
2011 Osman S, Waud WR, Gorman GS, Day BW, Koide K. Evaluation of FR901464 analogues in vitro and in vivo Medchemcomm. 2: 38-43. DOI: 10.1039/C0Md00179A  0.474
2010 Daghestani HN, Day BW. Theory and applications of surface plasmon resonance, resonant mirror, resonant waveguide grating, and dual polarization interferometry biosensors. Sensors (Basel, Switzerland). 10: 9630-46. PMID 22163431 DOI: 10.3390/S101109630  0.742
2010 Cherra SJ, Kulich SM, Uechi G, Balasubramani M, Mountzouris J, Day BW, Chu CT. Regulation of the autophagy protein LC3 by phosphorylation. The Journal of Cell Biology. 190: 533-9. PMID 20713600 DOI: 10.1083/Jcb.201002108  0.393
2010 Vogt A, Codore H, Day BW, Hukriede NA, Tsang M. Development of automated imaging and analysis for zebrafish chemical screens. Journal of Visualized Experiments : Jove. PMID 20613708 DOI: 10.3791/1900  0.369
2010 Zhu W, Jiménez M, Jung WH, Camarco DP, Balachandran R, Vogt A, Day BW, Curran DP. Streamlined syntheses of (-)-dictyostatin, 16-desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-desmethyl-25,26-dihydrodictyostatin. Journal of the American Chemical Society. 132: 9175-87. PMID 20545347 DOI: 10.1021/Ja103537U  0.781
2010 de Groh ED, Swanhart LM, Cosentino CC, Jackson RL, Dai W, Kitchens CA, Day BW, Smithgall TE, Hukriede NA. Inhibition of histone deacetylase expands the renal progenitor cell population. Journal of the American Society of Nephrology : Jasn. 21: 794-802. PMID 20378823 DOI: 10.1681/Asn.2009080851  0.769
2010 Lakshman MK, Singh MK, Parrish D, Balachandran R, Day BW. Azide-tetrazole equilibrium of C-6 azidopurine nucleosides and their ligation reactions with alkynes. The Journal of Organic Chemistry. 75: 2461-73. PMID 20297785 DOI: 10.1021/Jo902342Z  0.742
2010 You Z, Cao H, Gao J, Shin PH, Day BW, Wang Y. A functionalizable polyester with free hydroxyl groups and tunable physiochemical and biological properties. Biomaterials. 31: 3129-38. PMID 20149441 DOI: 10.1016/J.Biomaterials.2010.01.023  0.381
2010 Beckner ME, Fellows-Mayle W, Zhang Z, Agostino NR, Kant JA, Day BW, Pollack IF. Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas. International Journal of Cancer. Journal International Du Cancer. 126: 2282-95. PMID 19795461 DOI: 10.1002/Ijc.24918  0.469
2010 Yalowich JC, Hornbaker M, Bodnar AJ, Jin S, Zhang Y, Day BW, Fuchs JR, Li P. Abstract 3498: The cytotoxicity and genotoxicity of etoposide and other phenolic and non-phenolic agents in human myeloid leukemia HL-60 cells: role of myeloperoxidase (MPO) Cancer Research. 70: 3498-3498. DOI: 10.1158/1538-7445.Am10-3498  0.467
2010 Daghestani HN, Conway JF, Day BW. Cysteine Mapping of Cytoplasmic Dynein Motor Domain Biophysical Journal. 98: 726a. DOI: 10.1016/J.Bpj.2009.12.3979  0.757
2009 Emert-Sedlak L, Kodama T, Lerner EC, Dai W, Foster C, Day BW, Lazo JS, Smithgall TE. Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compounds. Acs Chemical Biology. 4: 939-47. PMID 19807124 DOI: 10.1021/Cb900195C  0.789
2009 Fan Y, Schreiber EM, Day BW. Human liver microsomal metabolism of (+)-discodermolide. Journal of Natural Products. 72: 1748-54. PMID 19775091 DOI: 10.1021/Np900245K  0.78
2009 Vogt A, McPherson PA, Shen X, Balachandran R, Zhu G, Raccor BS, Nelson SG, Tsang M, Day BW. High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. Chemical Biology & Drug Design. 74: 358-68. PMID 19691472 DOI: 10.1111/J.1747-0285.2009.00866.X  0.819
2009 Albert BJ, McPherson PA, O'Brien K, Czaicki NL, Destefino V, Osman S, Li M, Day BW, Grabowski PJ, Moore MJ, Vogt A, Koide K. Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells. Molecular Cancer Therapeutics. 8: 2308-18. PMID 19671752 DOI: 10.1158/1535-7163.Mct-09-0051  0.49
2009 Daghestani HN, Fernig DG, Day BW. Evaluation of biosensor surfaces for the detection of microtubule perturbation. Biosensors & Bioelectronics. 25: 136-41. PMID 19595587 DOI: 10.1016/J.Bios.2009.06.014  0.775
2009 Molina G, Vogt A, Bakan A, Dai W, Queiroz de Oliveira P, Znosko W, Smithgall TE, Bahar I, Lazo JS, Day BW, Tsang M. Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nature Chemical Biology. 5: 680-7. PMID 19578332 DOI: 10.1038/Nchembio.190  0.781
2009 Brummond KM, Mao S, Shinde SN, Johnston PJ, Day BW. Design and synthesis of a library of tetracyclic hydroazulenoisoindoles. Journal of Combinatorial Chemistry. 11: 486-94. PMID 19366169 DOI: 10.1021/Cc900024P  0.43
2009 Sarachine MJ, Janjic JM, Wipf P, Day BW. Biphenyl C-cyclopropylalkylamides: New scaffolds for targeting estrogen receptor beta. Bioorganic & Medicinal Chemistry Letters. 19: 2404-8. PMID 19356928 DOI: 10.1016/J.Bmcl.2009.03.075  0.794
2009 Gao X, Kuruba R, Damodaran K, Day BW, Liu D, Li S. Polyhydroxylalkyleneamines: a class of hydrophilic cationic polymer-based gene transfer agents. Journal of Controlled Release : Official Journal of the Controlled Release Society. 137: 38-45. PMID 19332088 DOI: 10.1016/J.Jconrel.2009.03.012  0.373
2009 Chiang AN, Valderramos JC, Balachandran R, Chovatiya RJ, Mead BP, Schneider C, Bell SL, Klein MG, Huryn DM, Chen XS, Day BW, Fidock DA, Wipf P, Brodsky JL. Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum. Bioorganic & Medicinal Chemistry. 17: 1527-33. PMID 19195901 DOI: 10.1016/J.Bmc.2009.01.024  0.774
2009 Tierno MB, Kitchens CA, Petrik B, Graham TH, Wipf P, Xu FL, Saunders WS, Raccor BS, Balachandran R, Day BW, Stout JR, Walczak CE, Ducruet AP, Reese CE, Lazo JS. Microtubule binding and disruption and induction of premature senescence by disorazole C(1). The Journal of Pharmacology and Experimental Therapeutics. 328: 715-22. PMID 19066338 DOI: 10.1124/Jpet.108.147330  0.807
2009 Kangani CO, Day BW. A novel and direct synthesis of 1,3,4-oxadiazoles or oxazolines from carboxylic acids using cyanuric chloride/indium Tetrahedron Letters. 50: 5332-5335. DOI: 10.1016/J.Tetlet.2009.07.032  0.379
2008 Su Y, Fu C, Ishikawa S, Stella A, Kojima M, Shitoh K, Schreiber EM, Day BW, Liu B. APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase. Molecular Cell. 32: 652-61. PMID 19061640 DOI: 10.1016/J.Molcel.2008.10.023  0.766
2008 Dietrich DR, Heussner AH, O'Brien E, Gramatté T, Runkel M, Rumpf S, Day BW. Propiverine-induced accumulation of nuclear and cytosolic protein in F344 rat kidneys: isolation and identification of the accumulating protein. Toxicology and Applied Pharmacology. 233: 411-9. PMID 18929589 DOI: 10.1016/J.Taap.2008.09.014  0.356
2008 Eiseman JL, Bai L, Jung WH, Moura-Letts G, Day BW, Curran DP. Improved synthesis of 6-epi-dictyostatin and antitumor efficacy in mice bearing MDA-MB231 human breast cancer xenografts. Journal of Medicinal Chemistry. 51: 6650-3. PMID 18839939 DOI: 10.1021/Jm800979V  0.469
2008 Gibson F, Anderson L, Babnigg G, Baker M, Berth M, Binz PA, Borthwick A, Cash P, Day BW, Friedman DB, Garland D, Gutstein HB, Hoogland C, Jones NA, Khan A, et al. Guidelines for reporting the use of gel electrophoresis in proteomics. Nature Biotechnology. 26: 863-4. PMID 18688234 DOI: 10.1038/Nbt0808-863  0.328
2008 Kangani CO, Day BW. Mild, efficient Friedel-Crafts acylations from carboxylic acids using cyanuric chloride and AlCl3. Organic Letters. 10: 2645-8. PMID 18512929 DOI: 10.1021/Ol800752V  0.767
2008 Thomas CA, Grant SG, Pflug BR, Getzenberg RH, Day BW. (Z)-1,1-Dichloro-2-(4-methoxyphenyl)-3-phenylcyclopropane induces concentration-dependent growth inhibition, apoptosis, and coordinates regulation of apoptotic genes in TRAMP cells. Urologic Oncology. 26: 378-85. PMID 18367102 DOI: 10.1016/J.Urolonc.2007.02.013  0.633
2008 Balachandran R, Hopkins TD, Thomas CA, Wipf P, Day BW. Tubulin-perturbing naphthoquinone spiroketals. Chemical Biology & Drug Design. 71: 117-24. PMID 18194192 DOI: 10.1111/J.1747-0285.2007.00616.X  0.809
2008 Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL. Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation. Bioorganic & Medicinal Chemistry. 16: 3291-301. PMID 18164205 DOI: 10.1016/J.Bmc.2007.12.014  0.621
2008 Raccor BS, Vogt A, Sikorski RP, Madiraju C, Balachandran R, Montgomery K, Shin Y, Fukui Y, Jung WH, Curran DP, Day BW. Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin. Molecular Pharmacology. 73: 718-26. PMID 18073274 DOI: 10.1124/Mol.107.042598  0.816
2008 Hukriede NA, De Groh ED, Jackson R, Dai W, Day BW, Smithgall TE. Utilizing a small molecule screen to delineate kidney development Developmental Biology. 319: 605-606. DOI: 10.1016/J.Ydbio.2008.05.450  0.348
2008 Kangani CO, Day BW, Kelley DE. Controlled conversion of phenylacetic acids to phenylacetonitriles or benzonitriles using bis(2-methoxyethyl)aminosulfur trifluoride Tetrahedron Letters. 49: 914-918. DOI: 10.1016/J.Tetlet.2007.11.090  0.38
2007 Shin Y, Fournier JH, Brückner A, Madiraju C, Balachandran R, Raccor BS, Edler MC, Hamel E, Sikorski RP, Vogt A, Day BW, Curran DP. Synthesis and biological evaluation of (-)-dictyostatin and stereoisomers. Tetrahedron. 63: 8537-8562. PMID 18728696 DOI: 10.1016/J.Tet.2007.05.033  0.816
2007 Wang Z, McPherson PA, Raccor BS, Balachandran R, Zhu G, Day BW, Vogt A, Wipf P. Structure-activity and high-content imaging analyses of novel tubulysins. Chemical Biology & Drug Design. 70: 75-86. PMID 17683369 DOI: 10.1111/J.1747-0285.2007.00541.X  0.8
2007 Wipf P, Gong H, Janjic JM, Li S, Day BW, Xie W. New opportunities for pregnane X receptor (PXR) targeting in drug development. lessons from Enantio- and species-specific PXR ligands identified from a discovery library of amino acid analogues. Mini Reviews in Medicinal Chemistry. 7: 617-25. PMID 17584160 DOI: 10.2174/138955707780859404  0.704
2007 Jung WH, Harrison C, Shin Y, Fournier JH, Balachandran R, Raccor BS, Sikorski RP, Vogt A, Curran DP, Day BW. Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin. Journal of Medicinal Chemistry. 50: 2951-66. PMID 17542572 DOI: 10.1021/Jm061385K  0.814
2007 Escobar PA, Olivero OA, Wade NA, Abrams EJ, Nesel CJ, Ness RB, Day RD, Day BW, Meng Q, O'Neill JP, Walker DM, Poirier MC, Walker VE, Bigbee WL. Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC. Environmental and Molecular Mutagenesis. 48: 330-43. PMID 17358027 DOI: 10.1002/Em.20285  0.38
2007 Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. Nature Chemical Biology. 3: 117-25. PMID 17206139 DOI: 10.1038/Nchembio853  0.45
2007 Heussner AH, Moeller I, Day BW, Dietrich DR, O'Brien E. Production and characterization of monoclonal antibodies against ochratoxin B. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 45: 827-33. PMID 17161512 DOI: 10.1016/J.Fct.2006.10.027  0.376
2007 Kangani CO, Day BW, Kelley DE. Direct, facile synthesis of acyl azides and nitriles from carboxylic acids using bis(2-methoxyethyl)aminosulfur trifluoride Tetrahedron Letters. 48: 5933-5937. DOI: 10.1016/J.Tetlet.2007.06.119  0.402
2006 Beckner ME, Zhang Z, Agostino NR, Day BW, Pollack IF. Albumin marks pseudopodia of astrocytoma cells responding to hepatocyte growth factor or serum. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1103-14. PMID 16969371 DOI: 10.1038/Labinvest.3700470  0.491
2006 Hamel E, Day BW, Miller JH, Jung MK, Northcote PT, Ghosh AK, Curran DP, Cushman M, Nicolaou KC, Paterson I, Sorensen EJ. Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly. Molecular Pharmacology. 70: 1555-64. PMID 16887932 DOI: 10.1124/Mol.106.027847  0.468
2006 Fan Y, Schreiber EM, Giorgianni A, Yalowich JC, Day BW. Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells. Chemical Research in Toxicology. 19: 937-43. PMID 16841962 DOI: 10.1021/Tx0600595  0.799
2006 Zhu G, Yang F, Balachandran R, Höök P, Vallee RB, Curran DP, Day BW. Synthesis and biological evaluation of purealin and analogues as cytoplasmic dynein heavy chain inhibitors. Journal of Medicinal Chemistry. 49: 2063-76. PMID 16539395 DOI: 10.1021/Jm051030L  0.806
2006 Balasubramani M, Day BW, Schoen RE, Getzenberg RH. Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer. Cancer Research. 66: 763-9. PMID 16424007 DOI: 10.1158/0008-5472.Can-05-3771  0.369
2006 Fukui Y, Brückner AM, Shin Y, Balachandran R, Day BW, Curran DP. Fluorous mixture synthesis of (-)-dictyostatin and three stereoisomers. Organic Letters. 8: 301-4. PMID 16408900 DOI: 10.1021/Ol0526827  0.755
2006 Atkins JL, Day BW, Handrigan MT, Zhang Z, Pamnani MB, Gorbunov NV. Brisk production of nitric oxide and associated formation of S-nitrosothiols in early hemorrhage. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 1267-77. PMID 16339342 DOI: 10.1152/Japplphysiol.01059.2005  0.445
2006 Khanday FA, Yamamori T, Mattagajasingh I, Zhang Z, Bugayenko A, Naqvi A, Santhanam L, Nabi N, Kasuno K, Day BW, Irani K. Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress. Molecular Biology of the Cell. 17: 122-9. PMID 16251354 DOI: 10.1091/Mbc.E05-06-0570  0.462
2006 Gong H, Singh SV, Singh SP, Mu Y, Lee JH, Saini SP, Toma D, Ren S, Kagan VE, Day BW, Zimniak P, Xie W. Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells. Molecular Endocrinology (Baltimore, Md.). 20: 279-90. PMID 16195250 DOI: 10.1210/Me.2005-0205  0.41
2006 Kangani CO, Kelley DE, Day BW. One pot direct synthesis of oxazolines, benzoxazoles, and oxadiazoles from carboxylic acids using the Deoxo-Fluor reagent Tetrahedron Letters. 47: 6497-6499. DOI: 10.1016/J.Tetlet.2006.07.032  0.384
2006 Kangani CO, Kelley DE, Day BW. One-pot synthesis of aldehydes or ketones from carboxylic acids via in situ generation of Weinreb amides using the Deoxo-Fluor reagent Tetrahedron Letters. 47: 6289-6292. DOI: 10.1016/J.Tetlet.2006.06.121  0.387
2005 Giuliano KA, Cheung WS, Curran DP, Day BW, Kassick AJ, Lazo JS, Nelson SG, Shin Y, Taylor DL. Systems cell biology knowledge created from high content screening. Assay and Drug Development Technologies. 3: 501-14. PMID 16305307 DOI: 10.1089/Adt.2005.3.501  0.452
2005 Madiraju C, Edler MC, Hamel E, Raccor BS, Balachandran R, Zhu G, Giuliano KA, Vogt A, Shin Y, Fournier JH, Fukui Y, Brückner AM, Curran DP, Day BW. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry. 44: 15053-63. PMID 16274252 DOI: 10.1021/Bi050685L  0.813
2005 Nguyen TL, McGrath C, Hermone AR, Burnett JC, Zaharevitz DW, Day BW, Wipf P, Hamel E, Gussio R. A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. Journal of Medicinal Chemistry. 48: 6107-16. PMID 16162011 DOI: 10.1021/Jm050502T  0.549
2005 Brisson M, Nguyen T, Wipf P, Joo B, Day BW, Skoko JS, Schreiber EM, Foster C, Bansal P, Lazo JS. Redox regulation of Cdc25B by cell-active quinolinediones. Molecular Pharmacology. 68: 1810-20. PMID 16155209 DOI: 10.1124/Mol.105.016360  0.804
2005 Shin Y, Fournier JH, Balachandran R, Madiraju C, Raccor BS, Zhu G, Edler MC, Hamel E, Day BW, Curran DP. Synthesis and biological evaluation of (-)-16-normethyldictyostatin: a potent analogue of (-)-dictyostatin. Organic Letters. 7: 2873-6. PMID 15987158 DOI: 10.1021/Ol050808U  0.801
2005 Mu Y, Stephenson CR, Kendall C, Saini SP, Toma D, Ren S, Cai H, Strom SC, Day BW, Wipf P, Xie W. A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development. Molecular Pharmacology. 68: 403-13. PMID 15872116 DOI: 10.1124/Mol.105.013292  0.526
2005 Keohavong P, Xi L, Day RD, Zhang L, Grant SG, Day BW, Ness RB, Bigbee WL. HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy. Mutation Research. 572: 156-66. PMID 15790499 DOI: 10.1016/J.Mrfmmm.2005.01.014  0.302
2005 Wipf P, Coleman CM, Janjic JM, Iyer PS, Fodor MD, Shafer YA, Stephenson CR, Kendall C, Day BW. Microwave-assisted "libraries from libraries" approach toward the synthesis of allyl- and C-cyclopropylalkylamides. Journal of Combinatorial Chemistry. 7: 322-30. PMID 15762763 DOI: 10.1021/Cc049842A  0.726
2005 Beckner ME, Chen X, An J, Day BW, Pollack IF. Proteomic characterization of harvested pseudopodia with differential gel electrophoresis and specific antibodies. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 316-27. PMID 15654357 DOI: 10.1038/Labinvest.3700239  0.422
2005 Cunningham SL, Cunningham AR, Day BW. CoMFA, HQSAR and molecular docking studies of butitaxel analogues with beta-tubulin. Journal of Molecular Modeling. 11: 48-54. PMID 15616834 DOI: 10.1007/S00894-004-0220-Y  0.435
2005 Janjic JM, Mu Y, Kendall C, Stephenson CR, Balachandran R, Raccor BS, Lu Y, Zhu G, Xie W, Wipf P, Day BW. New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides. Bioorganic & Medicinal Chemistry. 13: 157-64. PMID 15582460 DOI: 10.1016/J.Bmc.2004.09.048  0.794
2005 Day B, Zhang Z, Atkins J, Handrigan M, Pamnani M, Gorbunov N. Methods for mining and modeling of proteomics data sets—application to hemorrhagic shock Journal of Critical Care. 20: 387. DOI: 10.1016/J.Jcrc.2005.09.030  0.379
2004 Fewell SW, Smith CM, Lyon MA, Dumitrescu TP, Wipf P, Day BW, Brodsky JL. Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity. The Journal of Biological Chemistry. 279: 51131-40. PMID 15448148 DOI: 10.1074/Jbc.M404857200  0.526
2004 Cheng P, Kanterewicz B, Hershberger PA, McCarty KS, Day BW, Nichols M. Inhibition of estrogen receptor alpha-mediated transcription by antiestrogenic 1,1-dichloro-2,2,3-triarylcyclopropanes. Molecular Pharmacology. 66: 970-7. PMID 15235102 DOI: 10.1124/Mol.104.000752  0.448
2004 Banni S, Petroni A, Blasevich M, Carta G, Angioni E, Murru E, Day BW, Melis MP, Spada S, Ip C. Detection of conjugated C16 PUFAs in rat tissues as possible partial beta-oxidation products of naturally occurring conjugated linoleic acid and its metabolites. Biochimica Et Biophysica Acta. 1682: 120-7. PMID 15158763 DOI: 10.1016/J.Bbalip.2004.03.003  0.334
2004 Wipf P, Reeves JT, Day BW. Chemistry and biology of curacin A. Current Pharmaceutical Design. 10: 1417-37. PMID 15134491 DOI: 10.2174/1381612043384853  0.6
2003 Balachandran R, Welsh MJ, Day BW. Altered levels and regulation of stathmin in paclitaxel-resistant ovarian cancer cells. Oncogene. 22: 8924-30. PMID 14654788 DOI: 10.1038/Sj.Onc.1207060  0.746
2003 Cunningham AR, Cunningham SL, Day BW. Identification of structural components associated with cytostatic activity in MCF-7 but not in MDA-MB-231 cells. Bioorganic & Medicinal Chemistry. 11: 5249-58. PMID 14604689 DOI: 10.1016/J.Bmc.2003.08.018  0.501
2003 Mínguez JM, Kim SY, Giuliano KA, Balachandran R, Madiraju C, Day BW, Curran DP. Synthesis and biological assessment of simplified analogues of the potent microtubule stabilizer (+)-discodermolide. Bioorganic & Medicinal Chemistry. 11: 3335-57. PMID 12837544 DOI: 10.1016/S0968-0896(03)00186-X  0.819
2003 Choy N, Shin Y, Nguyen PQ, Curran DP, Balachandran R, Madiraju C, Day BW. Simplified discodermolide analogues: synthesis and biological evaluation of 4-epi-7-dehydroxy-14,16-didemethyl-(+)-discodermolides as microtubule-stabilizing agents. Journal of Medicinal Chemistry. 46: 2846-64. PMID 12825928 DOI: 10.1021/Jm0204136  0.81
2002 Minguez JM, Giuliano KA, Balachandran R, Madiraju C, Curran DP, Day BW. Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide. Molecular Cancer Therapeutics. 1: 1305-13. PMID 12516963  0.824
2002 Vogt A, Pestell KE, Day BW, Lazo JS, Wipf P. The antisignaling agent SC-alpha alpha delta 9, 4-(benzyl-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl)- 2-decanoylaminobutyric acid, is a structurally unique phospholipid analogue with phospholipase C inhibitory activity. Molecular Cancer Therapeutics. 1: 885-92. PMID 12481409  0.441
2002 Shin Y, Choy N, Turner TR, Balachandran R, Madiraju C, Day BW, Curran DP. Discodermolide/Dictyostatin hybrids: synthesis and biological evaluation. Organic Letters. 4: 4443-6. PMID 12465908 DOI: 10.1021/Ol026942L  0.789
2002 Wipf P, Reeves JT, Balachandran R, Day BW. Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A. Journal of Medicinal Chemistry. 45: 1901-17. PMID 11960501 DOI: 10.1021/Jm0105171  0.803
2002 Day BW, Kangani CO, Avor KS. Convenient syntheses of (2R,3S,4R)-3-(tert-butyldimethylsilanyloxy)-2,4-dimethyl-5-oxopentanoic acid methoxymethylamide from methacrolein. Preparation of C1-C7 and C17-C24 fragments of (+)-discodermolide Tetrahedron Asymmetry. 13: 1161-1165. DOI: 10.1016/S0957-4166(02)00261-6  0.419
2002 Dessì MA, Deiana M, Day BW, Rosa A, Banni S, Corongiu FP. Oxidative stability of polyunsaturated fatty acids: Effect of squalene European Journal of Lipid Science and Technology. 104: 506-512. DOI: 10.1002/1438-9312(200208)104:8<506::Aid-Ejlt506>3.0.Co;2-1  0.367
2001 Razzaghi H, Day BW, McClure RJ, Kamboh MI. Structure-function analysis of D9N and N291S mutations in human lipoprotein lipase using molecular modelling. Journal of Molecular Graphics & Modelling. 19: 487-94, 587-90. PMID 11552677 DOI: 10.1016/S1093-3263(00)00096-6  0.391
2001 Hasinoff BB, Chee GL, Day BW, Avor KS, Barnabé N, Thampatty P, Yalowich JC. Synthesis and biological activity of a photoaffinity etoposide probe. Bioorganic & Medicinal Chemistry. 9: 1765-71. PMID 11425578 DOI: 10.1016/S0968-0896(01)00102-X  0.433
2001 Kozusko F, Chen P, Grant SG, Day BW, Panetta JC. A mathematical model of in vitro cancer cell growth and treatment with the antimitotic agent curacin A. Mathematical Biosciences. 170: 1-16. PMID 11259801 DOI: 10.1016/S0025-5564(00)00065-1  0.58
2001 Lazo JS, Tamura K, Vogt A, Jung JK, Rodriguez S, Balachandran R, Day BW, Wipf P. Antimitotic actions of a novel analog of the fungal metabolite palmarumycin CP1. The Journal of Pharmacology and Experimental Therapeutics. 296: 364-71. PMID 11160619  0.412
2001 Fewell SW, Day BW, Brodsky JL. Identification of an inhibitor of hsc70-mediated protein translocation and ATP hydrolysis. The Journal of Biological Chemistry. 276: 910-4. PMID 11036084 DOI: 10.1074/Jbc.M008535200  0.446
2001 Zayas-Rivera B, Zhang L, Grant SG, Keohavong P, Day BW. Mutational spectrum of N-hydroxy-N-acetyl-4-aminobiphenyl at exon 3 of the HPRT gene Biomarkers. 6: 262-273. DOI: 10.1080/13547500010017367  0.356
2000 Balachandran R, Grant SG, Welsh MJ, Day BW. Z-1,1-Dichloro-2,3-diphenylcyclopropanes block human prostate carcinoma cell proliferation, inhibit prostate-specific antigen expression, and initiate apoptosis. The Prostate. 45: 277-88. PMID 11102952 DOI: 10.1002/1097-0045(20001201)45:4<277::Aid-Pros1>3.0.Co;2-W  0.422
2000 Day BW. Mutants yield a pharmacophore model for the tubulin-paclitaxel binding site. Trends in Pharmacological Sciences. 21: 321-4. PMID 10973074 DOI: 10.1016/S0165-6147(00)01521-2  0.369
2000 Goldman R, Day BW, Carver TA, Mauthe RJ, Turteltaub KW, Shields PG. Quantitation of benzo[a]pyrene-DNA adducts by postlabeling with 14C-acetic anhydride and accelerator mass spectrometry. Chemico-Biological Interactions. 126: 171-83. PMID 10862816 DOI: 10.1016/S0009-2797(00)00160-5  0.301
2000 Gorbunov NV, Pogue-Geile KL, Epperly MW, Bigbee WL, Draviam R, Day BW, Wald N, Watkins SC, Greenberger JS. Activation of the nitric oxide synthase 2 pathway in the response of bone marrow stromal cells to high doses of ionizing radiation. Radiation Research. 154: 73-86. PMID 10856968 DOI: 10.1667/0033-7587(2000)154[0073:Aotnos]2.0.Co;2  0.392
2000 Wipf P, Reeves JT, Balachandran R, Giuliano KA, Hamel E, Day BW. Synthesis and biological evaluation of a focused mixture library of analogues of the antimitotic marine natural product curacin A Journal of the American Chemical Society. 122: 9391-9395. DOI: 10.1021/Ja002213U  0.593
1999 Lange RW, Day BW, Lemus R, Tyurin VA, Kagan VE, Karol MH. Intracellular S-glutathionyl adducts in murine lung and human bronchoepithelial cells after exposure to diisocyanatotoluene. Chemical Research in Toxicology. 12: 931-6. PMID 10525268 DOI: 10.1021/Tx990045H  0.439
1999 Balachandran R, ter Haar E, Yalowich JC, Welsh MJ, Grant SG, Day BW. Induction of human breast cancer cell apoptosis from G2/M preceded by stimulation into the cell cycle by Z-1,1-dichloro-2,3-diphenylcyclopropane. Biochemical Pharmacology. 57: 97-110. PMID 9920290 DOI: 10.1016/S0006-2952(98)00289-5  0.718
1999 Day BW, Tyurin VA, Tyurina YY, Liu M, Facey JA, Carta G, Kisin ER, Dubey RK, Kagan VE. Peroxidase-catalyzed pro- versus antioxidant effects of 4-hydroxytamoxifen: enzyme specificity and biochemical sequelae. Chemical Research in Toxicology. 12: 28-37. PMID 9894015 DOI: 10.1021/Tx980137R  0.425
1998 Day BW, Bergamini S, Tyurina YY, Carta G, Tyurin VA, Kagan VE. beta-Carotene. An antioxidant or a target of oxidative stress in cells? Sub-Cellular Biochemistry. 30: 209-17. PMID 9932516  0.262
1998 Tyurin VA, Tyurina YY, Quinn PJ, Schor NF, Balachandran R, Day BW, Kagan VE. Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection. Brain Research. Molecular Brain Research. 60: 270-81. PMID 9757062 DOI: 10.1016/S0169-328X(98)00181-8  0.402
1998 Keohavong P, Shukla R, Melacrinos A, Day BW, Reha-Krantz L. Effects of bulky polycyclic aromatic hydrocarbon adducts on DNA replication by exonuclease-deficient T7 and T4 DNA polymerases. Dna and Cell Biology. 17: 541-9. PMID 9655247 DOI: 10.1089/Dna.1998.17.541  0.346
1998 Gorbunov NV, Tyurina YY, Salama G, Day BW, Claycamp HG, Argyros G, Elsayed NM, Kagan VE. Nitric oxide protects cardiomyocytes against tert-butyl hydroperoxide-induced formation of alkoxyl and peroxyl radicals and peroxidation of phosphatidylserine. Biochemical and Biophysical Research Communications. 244: 647-51. PMID 9535719 DOI: 10.1006/Bbrc.1997.7951  0.378
1998 Balachandran R, ter Haar E, Welsh MJ, Grant SG, Day BW. The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells--preliminary comparisons to paclitaxel. Anti-Cancer Drugs. 9: 67-76. PMID 9491794 DOI: 10.1097/00001813-199801000-00008  0.731
1998 Evans RW, Shaten BJ, Day BW, Kuller LH. Prospective association between lipid soluble antioxidants and coronary heart disease in men. The Multiple Risk Factor Intervention Trial. American Journal of Epidemiology. 147: 180-6. PMID 9457009 DOI: 10.1093/Oxfordjournals.Aje.A009432  0.326
1998 Verdier-Pinard P, Lai JY, Yoo HD, Yu J, Marquez B, Nagle DG, Nambu M, White JD, Falck JR, Gerwick WH, Day BW, Hamel E. Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells. Molecular Pharmacology. 53: 62-76. PMID 9443933 DOI: 10.1124/Mol.53.1.62  0.529
1998 Balachandran R, Grant SG, Welsh MJ, Day BW. Increased sensitivity of the antiestrogen-resistant MCF-7/LY2 human breast carcinoma cell line to apoptosis induced by the novel microtubule stabilizing agent (+)-discodermolide Breast Journal. 4: 409-419. DOI: 10.1046/J.1524-4741.1998.460409.X  0.517
1997 Kowalski RJ, Giannakakou P, Gunasekera SP, Longley RE, Day BW, Hamel E. The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells. Molecular Pharmacology. 52: 613-22. PMID 9380024 DOI: 10.1124/Mol.52.4.613  0.454
1997 Nowalk AJ, Vaughan KG, Day BW, Tencza SB, Mietzner TA. Metal-dependent conformers of the periplasmic ferric ion binding protein. Biochemistry. 36: 13054-9. PMID 9335567 DOI: 10.1021/Bi971413O  0.37
1997 ter Haar E, Hamel E, Balachandran R, Day BW. Cellular targets of the anti-breast cancer agent Z-1,1-dichloro-2,3-diphenylcyclopropane: type II estrogen binding sites and tubulin. Anticancer Research. 17: 1861-9. PMID 9216636  0.721
1997 Jonnalagadda SS, ter Haar E, Hamel E, Lin CM, Magarian RA, Day BW. Synthesis and biological evaluation of 1,1-dichloro-2,3-diarylcyclopropanes as antitubulin and anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 5: 715-22. PMID 9158870 DOI: 10.1016/S0968-0896(97)00014-X  0.808
1997 Day BW, Jin R, Basalyga DM, Kramarik JA, Karol MH. Formation, solvolysis, and transcarbamoylation reactions of bis(S-glutathionyl) adducts of 2,4- and 2,6-diisocyanatotoluene. Chemical Research in Toxicology. 10: 424-31. PMID 9114980 DOI: 10.1021/Tx960201+  0.408
1997 Tyurin VA, Carta G, Tyurina YY, Banni S, Day BW, Corongiu FP, Kagan VE. Peroxidase-catalyzed oxidation of beta-carotene in HL-60 cells and in model systems: involvement of phenoxyl radicals. Lipids. 32: 131-42. PMID 9075202 DOI: 10.1007/S11745-997-0017-0  0.303
1996 ter Haar E, Rosenkranz HS, Hamel E, Day BW. Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents. Bioorganic & Medicinal Chemistry. 4: 1659-71. PMID 8931935 DOI: 10.1016/0968-0896(96)00158-7  0.714
1996 Ritov VB, Banni S, Yalowich JC, Day BW, Claycamp HG, Corongiu FP, Kagan VE. Non-random peroxidation of different classes of membrane phospholipids in live cells detected by metabolically integrated cis-parinaric acid. Biochimica Et Biophysica Acta. 1283: 127-40. PMID 8809092 DOI: 10.1016/0005-2736(96)00083-1  0.33
1996 Osipov AN, Gorbunov NV, Day BW, Elsayed NM, Kagan VE. Electron spin resonance and mass spectral analysis of interactions of ferrylhemoglobin and ferrylmyoglobin with nitric oxide Methods in Enzymology. 268: 193-203. PMID 8782585 DOI: 10.1016/S0076-6879(96)68021-5  0.311
1996 Kagan VE, Day BW, Elsayed NM, Gorbunov NV. Dynamics of haemoglobin. Nature. 383: 30-1. PMID 8779713 DOI: 10.1038/383030B0  0.301
1996 Day BW, Jin R, Karol MH. In vivo and in vitro reactions of toluene diisocyanate isomers with guinea pig hemoglobin Chemical Research in Toxicology. 9: 568-573. PMID 8728499 DOI: 10.1021/Tx9501703  0.305
1996 ter Haar E, Day BW. Cytostatic and cytotoxic action of Z-1, 1-dichloro-2,3-diphenylcyclopropane in three human breast cancer cell lines. Anticancer Research. 16: 1107-15. PMID 8702221  0.702
1996 Stoyanovsky DA, Goldman R, Jonnalagadda SS, Day BW, Claycamp HG, Kagan VE. Detection and characterization of the electron paramagnetic resonance-silent glutathionyl-5,5-dimethyl-1-pyrroline N-oxide adduct derived from redox cycling of phenoxyl radicals in model systems and HL-60 cells Archives of Biochemistry and Biophysics. 330: 3-11. PMID 8651701 DOI: 10.1006/Abbi.1996.0219  0.405
1996 Gorbunov NV, Osipov AN, Sweetland MA, Day BW, Elsayed NM, Kagan VE. NO-Redox paradox: Direct oxidation of α-tocopherol and α-tocopherol-mediated oxidation of ascorbate Biochemical and Biophysical Research Communications. 219: 835-841. PMID 8645266 DOI: 10.1006/Bbrc.1996.0319  0.353
1996 ter Haar E, Day BW, Rosenkranz HS. Direct tubulin polymerization perturbation contributes significantly to the induction of micronuclei in vivo. Mutation Research. 350: 331-7. PMID 8600362 DOI: 10.1016/0027-5107(95)00175-1  0.686
1996 ter Haar E, Kowalski RJ, Hamel E, Lin CM, Longley RE, Gunasekera SP, Rosenkranz HS, Day BW. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol. Biochemistry. 35: 243-50. PMID 8555181 DOI: 10.1021/Bi9515127  0.734
1996 Ryan LK, Golenbock DT, Day BW, Wu J, Vermeulen MW. Proinflammatory cytokine production by C3H/HEJ mouse alveolar (AM), peritoneal (PM), and bone marrow (BM) macrophages stimulated with LPS, interferon-γ (IFN) and taxol Faseb Journal. 10: A1050.  0.19
1995 Gorbunov NV, Osipov AN, Day BW, Zayas-Rivera B, Kagan VE, Elsayed NM. Reduction of ferrylmyoglobin and ferrylhemoglobin by nitric oxide: a protective mechanism against ferryl hemoprotein-induced oxidations. Biochemistry. 34: 6689-99. PMID 7756300 DOI: 10.1021/Bi00020A014  0.356
1995 Goldman R, Stoyanovsky DA, Day BW, Kagan VE. Reduction of phenoxyl radicals by thioredoxin results in selective oxidation of its SH-groups to disulfides. An antioxidant function of thioredoxin. Biochemistry. 34: 4765-72. PMID 7718583 DOI: 10.1021/Bi00014A034  0.368
1995 Hopp L, Bunker CH, Day BW. Quinine sensitive changes in cellular Na+ and K+ homeostasis of COS-7 cells caused by a lipophilic phenol red impurity In Vitro Cellular & Developmental Biology - Animal. 31: 352-360. PMID 7543341 DOI: 10.1007/BF02634284  0.274
1995 Banni S, Day BW, Evans RW, Corongiu FP, Lombardi B. Detection of conjugated diene isomers of linoleic acid in liver lipids of rats fed a choline-devoid diet indicates that the diet does not cause lipoperoxidation The Journal of Nutritional Biochemistry. 6: 281-289. DOI: 10.1016/0955-2863(95)00049-6  0.313
1995 Day BW, Jonnalagadda SS. Synthesis of Z- and E-[2,3-2H2] and [2,3-3H2]-1,1-dichloro-2,3-diphenylcyclopropane (2H- and 3H-analog II and its trans isomer) Journal of Labelled Compounds and Radiopharmaceuticals. 36: 73-78. DOI: 10.1002/Jlcr.2580360109  0.386
1994 Hossain MB, van der Helm D, Schmitz FJ, Pordesimo EO, Magarian RA, Meyer KL, Overacre LB, Day BW. Molecular structures and conformational studies of triarylcyclopropyl and related nonsteroidal antiestrogens. Journal of Medicinal Chemistry. 37: 1670-83. PMID 8201601 DOI: 10.1021/Jm00037A018  0.681
1994 Kagan VE, Yalowich JC, Day BW, Goldman R, Gantchev TG, Stoyanovsky DA. Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems. Biochemistry. 33: 9651-60. PMID 8068642 DOI: 10.1021/Bi00198A034  0.387
1994 Day BW, Singh K. Analysis of hemoglobin adducts by fluorescence spectroscopy Methods in Enzymology. 231: 674-681. PMID 8041287 DOI: 10.1016/0076-6879(94)31048-3  0.339
1994 Day BW, Skipper PL, Zaia J, Singh K, Tannenbaum SR. Enantiospecificity of covalent adduct formation by benzo[a]pyrene anti-diol epoxide with human serum albumin. Chemical Research in Toxicology. 7: 829-35. PMID 7696539 DOI: 10.1021/Tx00042A017  0.552
1994 Ryan LK, Jin R, Boggs SS, Karol MH, Day BW. Mouse model for assessing endotoxin involvement in the lung inflammation and cytokine production resulting from inhaled organic dust Inhalation Toxicology. 6: 485-499. DOI: 10.3109/08958379409040506  0.332
1994 Banni S, Day BW, Evans RW, Corongiu FP, Lombardi B. Liquid chromatographic-mass spectrometric analysis of conjugated diene fatty acids in a partially hydrogenated fat Journal of the American Oil Chemists' Society. 71: 1321-1325. DOI: 10.1007/Bf02541348  0.352
1993 Tannenbaum SR, Skipper PL, Wishnok JS, Stillwell WG, Day BW, Taghizadeh K. Characterization of various classes of protein adducts. Environmental Health Perspectives. 99: 51-5. PMID 8319659 DOI: 10.1289/Ehp.939951  0.576
1993 Jin R, Day BW, Karol MH. Toluene diisocyanate protein adducts in the bronchoalveolar lavage of guinea pigs exposed to vapors of the chemical Chemical Research in Toxicology. 6: 906-912. PMID 8117932 DOI: 10.1021/Tx00036A023  0.37
1993 Yalowich J, Claycamp H, Stoyanovsky D, Allan W, Gantchev T, Day B, Kagan V. Two faces of the phenolic antitumor drug etoposide (VP-16): Free radical enhancement of cytotoxicity and protection against free radical-induced DNA damage Free Radical Biology and Medicine. 15: 493. DOI: 10.1016/0891-5849(93)90269-Z  0.235
1992 Day BW, Doxtader MM, Rich RH, Skipper PL, Singh K, Dasari RR, Tannenbaum SR. Human serum albumin-benzo[a]pyrene anti-diol epoxide adduct structure elucidation by fluorescence line narrowing spectroscopy. Chemical Research in Toxicology. 5: 71-6. PMID 1581540 DOI: 10.1021/Tx00025A012  0.515
1992 Day BW, Sahali Y, Hutchins DA, Wildschütte M, Pastorelli R, Nguyen TT, Naylor S, Skipper PL, Wishnok JS, Tannenbaum SR. Fluoranthene metabolism: human and rat liver microsomes display different stereoselective formation of the trans-2,3-dihydrodiol. Chemical Research in Toxicology. 5: 779-86. PMID 1489928 DOI: 10.1021/Tx00030A008  0.543
1992 Du L, Hossain MB, Ji X, van der Helm D, Magarian RA, Day BW. Structure of 1,1-dichloro-2-(4-methoxyphenyl)-2,3-diphenylcyclopropane. Acta Crystallographica. Section C, Crystal Structure Communications. 48: 887-91. PMID 1388936 DOI: 10.1107/S0108270191011186  0.669
1991 Day BW, Naylor S, Gan LS, Sahali Y, Nguyen TT, Skipper PL, Wishnok JS, Tannenbaum SR. Gas chromatographic-mass spectrometric analysis of diols and tetrols from reactions of polycyclic aromatic hydrocarbon epoxides with hemoglobin. Journal of Chromatography. 562: 563-71. PMID 2026719 DOI: 10.1016/0378-4347(91)80608-F  0.529
1991 Day BW, Magarian RA, Jain PT, Pento JT, Mousissian GK, Meyer KL. Synthesis and biological evaluation of a series of 1,1-dichloro-2,2,3-triarylcyclopropanes as pure antiestrogens. Journal of Medicinal Chemistry. 34: 842-51. PMID 1995907  0.719
1991 Hossain MB, Wang JL, van der Helm D, Magarian RA, Griffin MT, Day BW. Structural comparison of a gem-dichlorodiarylcyclopropane antiestrogen and three of its derivatives. Acta Crystallographica. Section B, Structural Science. 47: 511-21. PMID 1930832 DOI: 10.1107/S0108768191000976  0.672
1991 Day BW, Skipper PL, Rich RH, Naylor S, Tannenbaum SR. Conversion of a hemoglobin alpha chain aspartate(47) ester to N-(2,3-dihydroxypropyl)asparagine as a method for identification of the principal binding site for benzo[a]pyrene anti-diol epoxide. Chemical Research in Toxicology. 4: 359-63. PMID 1912320 DOI: 10.1021/Tx00021A016  0.492
1991 Day BW, Skipper PL, Zaia J, Tannenbaum SR. Benzo[a]pyrene anti-diol epoxide covalently modifies human serum albumin carboxylate side chains and imidazole side chain of histidine(146) Journal of the American Chemical Society. 113: 8505-8509. DOI: 10.1021/Ja00022A044  0.522
1990 Day BW, Naylor S, Gan LS, Sahali Y, Nguyen TT, Skipper PL, Wishnok JS, Tannenbaum SR. Molecular dosimetry of polycyclic aromatic hydrocarbon epoxides and diol epoxides via hemoglobin adducts. Cancer Research. 50: 4611-8. PMID 2369737  0.521
1990 Day BW, Skipper PL, Wishnok JS, Coghlin J, Hammond SK, Gann P, Tannenbaum SR. Identification of an in vivo chrysene diol epoxide adduct in human hemoglobin. Chemical Research in Toxicology. 3: 340-3. PMID 2133082 DOI: 10.1021/Tx00016A011  0.51
1990 Naylor S, Gan LS, Day BW, Pastorelli R, Skipper PL, Tannenbaum SR. Benzo[a]pyrene diol epoxide adduct formation in mouse and human hemoglobin: physicochemical basis for dosimetry. Chemical Research in Toxicology. 3: 111-7. PMID 2130937 DOI: 10.1021/Tx00014A005  0.586
1990 Jankowiak R, Day BW, Lu PQ, Doxtader MM, Skipper PL, Tannenbaum SR, Small GJ. Fluorescence line-narrowing spectral analysis of in vivo human hemoglobin-benzo[a]pyrene adducts: Comparison to synthetic analogues Journal of the American Chemical Society. 112: 5866-5869. DOI: 10.1021/Ja00171A030  0.583
1990 Naylor S, Skipper P, Gan L, Day B, Tannebaum S. Origins of the tetrols arising from hemoglobinbenzo[a]pyrene diolepoxide adducts determined by incorporation of 18O from H218O Mutation Research/Environmental Mutagenesis and Related Subjects. 234: 377. DOI: 10.1016/0165-1161(90)90068-Y  0.205
1989 Skipper PL, Naylor S, Gan LS, Day BW, Pastorelli R, Tannenbaum SR. Origin of tetrahydrotetrols derived from human hemoglobin adducts of benzo[a]pyrene. Chemical Research in Toxicology. 2: 280-1. PMID 2519818 DOI: 10.1021/Tx00011A002  0.529
1989 Naylor S, Gan LS, Day BW, Skipper PL, Tannenbaum SR. A rapid method for isolation of human hemoglobin benzo[a]pyrene diol epoxide derived adducts using high performance liquid chromatography. Biomedical Chromatography : Bmc. 3: 266-8. PMID 2515899 DOI: 10.1002/Bmc.1130030608  0.495
1985 Pento JT, Day BW. ACC-9089 Drugs of the Future. 10: 447-448.  0.178
1985 Pento JT, Day BW. Epanolol Drugs of the Future. 10: 392-393.  0.266
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