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Year Citation  Score
2014 Eckstein F. Phosphorothioates, essential components of therapeutic oligonucleotides. Nucleic Acid Therapeutics. 24: 374-87. PMID 25353652 DOI: 10.1089/Nat.2014.0506  0.312
2000 Bramlage B, Luzi E, Eckstein F. HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: Site selection and inhibition in cell culture Nucleic Acids Research. 28: 4059-4067. PMID 11058100 DOI: 10.1093/Nar/28.21.4059  0.303
2000 Kore AR, Vaish NK, Morris JA, Eckstein F. In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues. Journal of Molecular Biology. 301: 1113-21. PMID 10966809 DOI: 10.1006/Jmbi.2000.4020  0.313
1999 Eckstein F, Bramlage B. The hammerhead ribozyme Biopolymers. 52: 147-154. PMID 11169382 DOI: 10.1042/Bst0240601  0.322
1999 Kore AR, Eckstein F. Hammerhead ribozyme mechanism: A ribonucleotide 5' to the substrate cleavage site is not essential Biochemistry. 38: 10915-10918. PMID 10460146 DOI: 10.1021/Bi991332N  0.309
1999 Carola C, Eckstein F. Nucleic acid enzymes Current Opinion in Chemical Biology. 3: 274-283. PMID 10359709 DOI: 10.1016/S1367-5931(99)80043-X  0.308
1999 Citti L, Eckstein F, Capecchi B, Mariani L, Nevischi S, Poggi A, Rainaldi G. Transient transfection of a synthetic hammerhead ribozyme targeted against human MGMT gene to cells in culture potentiates the genotoxicity of the alkylation damage induced by mitozolomide Antisense and Nucleic Acid Drug Development. 9: 125-133. PMID 10355819 DOI: 10.1089/Oli.1.1999.9.125  0.339
1998 Vörtler CS, Fedorova O, Persson T, Kutzke U, Eckstein F. Determination of 2'-hydroxyl and phosphate groups important for aminoacylation of Escherichia coli tRNA(Asp): A nucleotide analogue interference study Rna. 4: 1444-1454. PMID 9814764 DOI: 10.1017/S1355838298980967  0.306
1998 Alefelder S, Patel BK, Eckstein F. Incorporation of terminal phosphorothioates into oligonucleotides Nucleic Acids Research. 26: 4983-4988. PMID 9776763 DOI: 10.1093/Nar/26.21.4983  0.55
1998 Venna S, Eckstein F. Modified oligonucleotides: Synthesis and strategy for users Annual Review of Biochemistry. 67: 99-134. PMID 9759484 DOI: 10.1146/Annurev.Biochem.67.1.99  0.333
1998 Vaish NK, Heaton PA, Fedorova O, Eckstein F. In vitro selection of a purine nucleotide-specific hammerhead-like ribozyme Proceedings of the National Academy of Sciences of the United States of America. 95: 2158-2162. PMID 9482855 DOI: 10.1073/Pnas.95.5.2158  0.328
1997 Verma S, Vaish NK, Eckstein F. Structure-function studies of the hammerhead ribozyme Current Opinion in Chemical Biology. 1: 532-536. PMID 9667883 DOI: 10.1016/S1367-5931(97)80049-X  0.302
1997 Earnshaw DJ, Masquida B, Müller S, Sigurdsson ST, Eckstein F, Westhof E, Gait MJ. Inter-domain cross-linking and molecular modelling of the hairpin ribozyme. Journal of Molecular Biology. 274: 197-212. PMID 9398527 DOI: 10.1006/Jmbi.1997.1405  0.554
1997 Luzi E, Eckstein F, Barsacchi G. The newt ribozyme is part of a riboprotein complex. Proceedings of the National Academy of Sciences of the United States of America. 94: 9711-6. PMID 9275189 DOI: 10.1073/Pnas.94.18.9711  0.34
1997 Marusic L, Luzi E, Barsacchi G, Eckstein F. Intermolecular cleavage by the newt ribozyme. European Journal of Biochemistry / Febs. 247: 396-401. PMID 9249052 DOI: 10.1111/J.1432-1033.1997.00396.X  0.304
1997 Birikh KR, Heaton PA, Eckstein F. The structure, function and application of the hammerhead ribozyme European Journal of Biochemistry. 245: 1-16. PMID 9128718 DOI: 10.1111/J.1432-1033.1997.T01-3-00001.X  0.312
1997 Persson T, Vortler CS, Fedorova O, Eckstein F. Incorporation of 2'-modified nucleotides into tRNA to test importance for charging Nucleosides and Nucleotides. 16: 797-800. DOI: 10.1080/07328319708002954  0.344
1997 Patel BK, Eckstein F. 5'-Deoxy-5'-thioribonucleoside-5'-triphosphates Tetrahedron Letters. 38: 1021-1024. DOI: 10.1016/S0040-4039(97)00084-1  0.532
1996 Thomson JB, Patel BK, Jiménez V, Eckart K, Eckstein F. Synthesis and Properties of Diuridine Phosphate Analogues Containing Thio and Amino Modifications. The Journal of Organic Chemistry. 61: 6273-6281. PMID 11667467 DOI: 10.1021/Jo960795L  0.519
1996 Sigurdsson ST, Seeger B, Kutzke U, Eckstein F. A Mild and Simple Method for the Preparation of Isocyanates from Aliphatic Amines Using Trichloromethyl Chloroformate. Synthesis of an Isocyanate Containing an Activated Disulfide. The Journal of Organic Chemistry. 61: 3883-3884. PMID 11667245 DOI: 10.1021/Jo9521920  0.556
1996 Thomson JB, Sigurdsson ST, Zeuch A, Eckstein F. In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II. Nucleic Acids Research. 24: 4401-6. PMID 8948630 DOI: 10.1093/Nar/24.22.4401  0.548
1996 Menger M, Tuschl T, Eckstein F, Porschke D. Mg(2+)-dependent conformational changes in the hammerhead ribozyme. Biochemistry. 35: 14710-6. PMID 8942631 DOI: 10.1021/Bi960440W  0.512
1996 Sigurdsson ST, Eckstein F. Isolation of oligoribonucleotides containing intramolecular cross-links. Analytical Biochemistry. 235: 241-2. PMID 8833336 DOI: 10.1006/Abio.1996.0120  0.514
1996 Snorri TS, Eckstein F. Site specific labelling of sugar residues in oligoribonucleotides: Reactions of aliphatic isocyanates with 2' amino groups Nucleic Acids Research. 24: 3129-3133. PMID 8774891 DOI: 10.1093/Nar/24.16.3129  0.304
1996 Heaton PA, Eckstein F. Diastereomeric specificity of 2′,3′-cyclic nucleotide 3′-phosphodiesterase Nucleic Acids Research. 24: 850-853. PMID 8600451 DOI: 10.1093/Nar/24.5.850  0.321
1996 Schmidt S, Earnshaw DJ, Sigurdsson ST, Eckstein F, Gait MJ. Probing the tertiary structure of the hairpin ribozyme by chemical crosslinking Collection of Czechoslovak Chemical Communications. 61: 276-279. DOI: 10.1135/Cccc1996S276  0.539
1996 Sigurdsson ST, Seeger B, Kutzke U, Eckstein F. A mild and simple method for the preparation of isocyanates from aliphatic amines using trichloromethyl chloroformate. synthesis of an isocyanate containing an activated disulfide Journal of Organic Chemistry. 61: 3883-3884.  0.509
1995 Sigurdsson ST, Eckstein F. Structure-function relationships of hammerhead ribozymes: from understanding to applications. Trends in Biotechnology. 13: 286-9. PMID 7662303 DOI: 10.1016/S0167-7799(00)88966-0  0.571
1995 Heidenreich O, Kang SH, Brown DA, Xu X, Swiderski P, Rossi JJ, Eckstein F, Nerenberg M. Ribozyme-mediated RNA degradation in nuclei suspension Nucleic Acids Research. 23: 2223-2228. PMID 7610051 DOI: 10.1093/Nar/23.12.2223  0.317
1995 Tuschl T, Thomson JB, Eckstein F. RNA cleavage by small catalytic RNAs. Current Opinion in Structural Biology. 5: 296-302. PMID 7583627 DOI: 10.1016/0959-440X(95)80090-5  0.544
1995 Sigurdsson ST, Tuschl T, Eckstein F. Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme. Rna (New York, N.Y.). 1: 575-83. PMID 7489517  0.623
1994 Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity. Nucleic Acids Research. 22: 20-4. PMID 8127651 DOI: 10.1093/Nar/22.1.20  0.535
1994 Nakamaye KL, Eckstein F. AUA-cleaving hammerhead ribozymes: Attempted selection for improved cleavage Biochemistry. 33: 1271-1277. PMID 8110761 DOI: 10.1021/Bi00171A030  0.326
1994 Tuschl T, Gohlke C, Jovin TM, Westhof E, Eckstein F. A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science (New York, N.Y.). 266: 785-9. PMID 7973630 DOI: 10.1126/Science.7973630  0.527
1994 Ng MM, Benseler F, Tuschl T, Eckstein F. Isoguanosine substitution of conserved adenosines in the hammerhead ribozyme. Biochemistry. 33: 12119-26. PMID 7918433 DOI: 10.1021/Bi00206A015  0.482
1994 Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Oligonucleotide duplexes containing 2′-amino-2′deoxycytidines: Thermal stability and chemical reactivity Nucleic Acids Research. 22: 701. DOI: 10.1093/nar/22.4.701  0.442
1994 Tuschl T, Ng MMP, Pieken W, Benseler F, Eckstein F. Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. [Erratum to document cited in CA119(23):244321x] Biochemistry. 33: 848-848. DOI: 10.1021/Bi00169A028  0.481
1993 Tuschl T, Eckstein F. Hammerhead ribozymes: importance of stem-loop II for activity. Proceedings of the National Academy of Sciences of the United States of America. 90: 6991-4. PMID 8346207 DOI: 10.1073/Pnas.90.15.6991  0.497
1993 Eckstein F, Aurup H, Benseler F, Heidenreich O, Marschall P, Ng M, Thomson J, Tuschl T. Design of hammerhead ribozymes for the inhibition of gene expression ex vivo by exogenous application. Nucleic Acids Symposium Series. 115. PMID 8247729  0.409
1993 Tuschl T, Ng MM, Pieken W, Benseler F, Eckstein F. Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. Biochemistry. 32: 11658-68. PMID 8218233 DOI: 10.1021/Bi00094A023  0.53
1993 Herschlag D, Eckstein F, Cech TR. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Biochemistry. 32: 8312-21. PMID 7688573 DOI: 10.1021/Bi00083A035  0.323
1993 Herschlag D, Eckstein F, Cech TR. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA. Biochemistry. 32: 8299-311. PMID 7688572 DOI: 10.1021/Bi00083A034  0.363
1993 Heidenreich O, Pieken W, Eckstein F. Chemically modified RNA: Approaches and applications Faseb Journal. 7: 90-96. PMID 7678566 DOI: 10.1096/Fasebj.7.1.7678566  0.344
1993 Thomson JB, Tuschl T, Eckstein F. Activity of hammerhead ribozymes containing non-nucleotidic linkers. Nucleic Acids Research. 21: 5600-3. PMID 7506829 DOI: 10.1093/Nar/21.24.5600  0.521
1992 Williams DM, Pieken WA, Eckstein F. Function of specific 2′-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2′ modifications Proceedings of the National Academy of Sciences of the United States of America. 89: 918-921. PMID 1736306 DOI: 10.1073/Pnas.89.3.918  0.348
1992 Aurup H, Williams DM, Eckstein F. 2′-Fluoro- and 2′-amino-2′-deoxynucleoside 5′-triphosphates as substrates for T7 RNA polymerase Biochemistry. 31: 9636-9641. PMID 1390741 DOI: 10.1021/Bi00155A016  0.346
1992 Benseler F, Williams DM, Eckstein F. Synthesis of suitably-protected phosphoramidites of 2‘-fluoro-2’-deoxyguanosine and ‘-amino-2’-deoxyguanosine for incorporation into oligoribonucleotides Nucleosides and Nucleotides. 11: 1333-1351. DOI: 10.1080/07328319208021177  0.307
1991 Olsen DB, Kotzorek G, Eckstein F. Investigation of the inhibitory role of phosphorothioate internucleotidic linkages on the catalytic activity of the restriction endonuclease EcoRV. Biochemistry. 29: 9546-51. PMID 2271600 DOI: 10.1021/Bi00493A008  0.353
1991 Schatz D, Leberman R, Eckstein F. Interaction of Escherichia coli tRNA(Ser) with its cognate aminoacyl-tRNA synthetase as determined by footprinting with phosphorothioate-containing tRNA transcripts. Proceedings of the National Academy of Sciences of the United States of America. 88: 6132-6. PMID 2068094 DOI: 10.1073/Pnas.88.14.6132  0.33
1991 Williams DM, Benseler F, Eckstein F. Properties of 2'-fluorothymidine-containing oligonucleotides: interaction with restriction endonuclease EcoRV. Biochemistry. 30: 4001-9. PMID 2018768 DOI: 10.1021/Bi00230A027  0.317
1991 Ueda T, Tohda H, Chikazumi N, Eckstein F, Watanabe K. Phosphorothioate-containing RNAs show mRNA activity in the prokaryotic translation systems in vitro. Nucleic Acids Research. 19: 547-52. PMID 2011526 DOI: 10.1093/Nar/19.3.547  0.325
1991 Olsen DB, Benseler F, Aurup H, Pieken WA, Eckstein F. Study of a hammerhead ribozyme containing 2'-modified adenosine residues. Biochemistry. 30: 9735-41. PMID 1911762 DOI: 10.1021/Bi00104A024  0.365
1991 Pieken WA, Olsen DB, Benseler F, Aurup H, Eckstein F. Kinetic characterization of ribonuclease-resistant 2'-modified hammerhead ribozymes. Science (New York, N.Y.). 253: 314-7. PMID 1857967 DOI: 10.1126/Science.1857967  0.337
1991 Sayers JR, Eckstein F. A single-strand specific endonuclease activity copurifies with overexpressed T5 D15 exonuclease. Nucleic Acids Research. 19: 4127-32. PMID 1651477 DOI: 10.1093/Nar/19.15.4127  0.306
1991 Olsen DB, Sayers JR, Kotzorek G, Eckstein F. Interaction of Restriction Endonucleases with Phosphorothioate-Containing DNA Nucleosides and Nucleotides. 10: 665-667. DOI: 10.1080/07328319108046566  0.307
1990 Olsen DB, Eckstein F. High-efficiency oligonucleotide-directed plasmid mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 87: 1451-5. PMID 2154748 DOI: 10.1073/Pnas.87.4.1451  0.309
1990 van Tol H, Buzayan JM, Feldstein PA, Eckstein F, Bruening G. Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration Nucleic Acids Research. 18: 1971-1975. PMID 1692411 DOI: 10.1093/Nar/18.8.1971  0.341
1989 Nakamaye KL, Gish G, Eckstein F, Vosberg HP. Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside alpha-thiotriphosphates. Nucleic Acids Research. 16: 9947-59. PMID 3194230 DOI: 10.1093/Nar/16.21.9947  0.325
1989 Eckstein F, Gish G. Phosphorothioates in molecular biology. Trends in Biochemical Sciences. 14: 97-100. PMID 2658220 DOI: 10.1016/0968-0004(89)90130-8  0.321
1988 Spitzer S, Eckstein F. Inhibition of deoxyribonucleases by phosphorothioate groups in oligodeoxyribonucleotides Nucleic Acids Research. 16: 11691-11704. PMID 2850541 DOI: 10.1093/Nar/16.24.11691  0.305
1988 Sayers JR, Schmidt W, Wendler A, Eckstein F. Strand specific cleavage of phosphorothioate-containing DNA by reaction with restriction endonucleases in the presence of ethidium bromide. Nucleic Acids Research. 16: 803-14. PMID 2830594 DOI: 10.1093/Nar/16.3.803  0.319
1988 Sayers JR, Schmidt W, Eckstein F. 5'-3' exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis. Nucleic Acids Research. 16: 791-802. PMID 2830593 DOI: 10.1093/Nar/16.3.791  0.31
1988 Gish G, Eckstein F. DNA and RNA sequence determination based on phosphorothioate chemistry. Science (New York, N.Y.). 240: 1520-2. PMID 2453926 DOI: 10.1126/Science.2453926  0.355
1987 Nakamaye KL, Eckstein F. Inhibition of restriction endonuclease Nci I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis. Nucleic Acids Research. 14: 9679-98. PMID 3027659 DOI: 10.1093/Nar/14.24.9679  0.324
1986 Taylor JW, Ott J, Eckstein F. The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Research. 13: 8765-85. PMID 3001650 DOI: 10.1093/Nar/13.24.8765  0.308
1986 Taylor JW, Schmidt W, Cosstick R, Okruszek A, Eckstein F. The use of phosphorothioate-modified DNA in restriction enzyme reactions to prepare nicked DNA. Nucleic Acids Research. 13: 8749-64. PMID 3001649 DOI: 10.1093/Nar/13.24.8749  0.32
1986 Eckstein F, Kutzke U. Synthesis of nucleoside 3′,5′-cyclic phosphorothioates Tetrahedron Letters. 27: 1657-1660. DOI: 10.1016/S0040-4039(00)84340-3  0.304
1984 Connolly BA, Eckstein F, Grotjahn L. Direct mass spectroscopic method for determination of oxygen isotope position in adenosine 5′-O-(1-thiotriphosphate). determination of the stereochemical course of the yeast phenylalanyl-trna synthetase reaction Biochemistry. 23: 2026-2031. PMID 6372864 DOI: 10.1021/Bi00304A022  0.306
1984 Cosstick R, McLaughlin LW, Eckstein F. Fluorescent labelling of tRNA and oligodeoxynucleotides using T4 RNA ligase. Nucleic Acids Research. 12: 1791-810. PMID 6366740 DOI: 10.1093/Nar/12.4.1791  0.356
1984 Potter BV, Eckstein F. Cleavage of phosphorothioate-substituted DNA by restriction endonucleases. The Journal of Biological Chemistry. 259: 14243-8. PMID 6094546  0.449
1984 Connolly BA, Potter BVL, Eckstein F, Pingoud A, Grotjahn L. Synthesis and characterization of an octanucleotide containing the EcoRI recognition sequence with a phosphorothioate group at the cleavage site Biochemistry. 23: 3443-3453. PMID 6087894 DOI: 10.1021/Bi00310A010  0.333
1983 Potter BV, Eckstein F, Uznański B. A stereospecifically 18O-labelled deoxydinucleoside phosphate block for incorporation into an oligonucleotide. Nucleic Acids Research. 11: 7087-103. PMID 6634410 DOI: 10.1093/Nar/11.20.7087  0.494
1983 Potter BVL, Connolly BA, Eckstein F. Synthesis and configurational analysis of a dinucleoside phosphate isotopically chiral at phosphorus. Stereochemical course of Penicillium citrum nuclease P1 reaction Biochemistry. 22: 1369-1377. PMID 6301546 DOI: 10.1021/Bi00275A008  0.302
1983 Potter BV, Romaniuk PJ, Eckstein F. Stereochemical course of DNA hydrolysis by nuclease S1 Journal of Biological Chemistry. 258: 1758-1760. PMID 6296110  0.443
1983 Eckstein F. Phosphorothioate Analogues of Nucleotides?Tools for the Investigation of Biochemical Processes Angewandte Chemie International Edition in English. 22: 423-439. DOI: 10.1002/Anie.198304233  0.33
1982 Connolly BA, Eckstein F. S-methylated nucleoside phosphorothioates as probes of enzyme metal·nucleotide binding sites Biochemistry. 21: 6158-6167. PMID 7150548 DOI: 10.1021/Bi00267A021  0.321
1979 Strotmann H, Bickel-Sandkötter S, Edelmann K, Eckstein F, Schlimme E, Boos KS, Lüstorff J. Thiophosphate analogs of ADP and ATP as substrates in partial reactions of energy conversion in chloroplasts. Biochimica Et Biophysica Acta. 545: 122-30. PMID 758935 DOI: 10.1016/0005-2728(79)90119-1  0.304
1979 Armstrong VW, Eckstein F. Affinity labeling of the 3'-OH terminal binding site of the ribonucleic acid chain on deoxyribonucleic acid dependent ribonucleic acid polymerase from Escherichia coli. Biochemistry. 18: 5117-22. PMID 387081 DOI: 10.1021/Bi00590A014  0.348
1979 Yee D, Armstrong VW, Eckstein F. Mechanistic studies on deoxyribonucleic acid dependent ribonucleic acid polymerase from Escherichia coli using phosphorothioate analogues. 1. Initiation and pyrophosphate exchange reactions. Biochemistry. 18: 4116-20. PMID 226121 DOI: 10.1021/Bi00586A009  0.36
1979 Burgers PM, Eckstein F. Diastereomers of 5'-O-adenosyl 3'-O-uridyl phosphorothioate: chemical synthesis and enzymatic properties. Biochemistry. 18: 592-6. PMID 217419 DOI: 10.1021/Bi00571A007  0.319
1977 Armstrong V, Sternbach H, Eckstein F. 5-Formyl-UTP for DNA-dependent RNA polymerase. Methods in Enzymology. 46: 346-52. PMID 909423 DOI: 10.1016/S0076-6879(77)46040-3  0.335
1977 Vosberg HP, Eckstein F. Incorporation of phosphorothioate groups into fd and phi X174 DNA. Biochemistry. 16: 3633-40. PMID 329875 DOI: 10.1021/Bi00635A020  0.319
1977 Eckstein F, Sternbach H, von der Haar F. Stereochemistry of internucleotidic bond formation by tRNA nucleotidyltransferase from baker's yeast. Biochemistry. 16: 3429-32. PMID 329872 DOI: 10.1021/Bi00634A021  0.304
1976 Eckstein F, Bruns W, Parmeggiani A. Synthesis of guanosine 5'-di- and -triphosphate derivatives with modified terminal phosphates: effect on ribosome-elongation factor G-dependent reactions. Biochemistry. 14: 5225-32. PMID 1103967 DOI: 10.1021/Bi00694A033  0.312
1976 Armstrong VW, Eckstein F. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. European Journal of Biochemistry / Febs. 70: 33-8. PMID 795650 DOI: 10.1111/J.1432-1033.1976.Tb10952.X  0.368
1976 Armstrong VW, Sternbach H, Eckstein F. Modification of an essential arginine in Escherichia coli DNA-dependent RNA polymerase. Febs Letters. 70: 48-50. PMID 791678 DOI: 10.1016/0014-5793(76)80723-5  0.345
1976 Eckstein F, Armstrong VW, Sternbach H. Stereochemistry of polymerization by DNA-dependent RNA-polymerase from Escherichia coli: an investigation with a diastereomeric ATP-analogue. Proceedings of the National Academy of Sciences of the United States of America. 73: 2987-90. PMID 787980 DOI: 10.1073/Pnas.73.9.2987  0.361
1976 Pimmer J, Holler E, Eckstein F. l-Phenylalanine: tRNA Ligase of Escherichia coli K10 Febs Journal. 67: 171-176. PMID 786618 DOI: 10.1111/J.1432-1033.1976.Tb10646.X  0.32
1976 Hobbs J, Eckstein F. Hydrolysis in 2'-chloro-2'-deoxy nucleosides, -nucleotides and -polynucleotides to arabinose-derivatives. Nucleic Acids Research. 2: 1987-94. PMID 174061 DOI: 10.1093/Nar/2.10.1987  0.306
1974 Saenger W, Suck D, Eckstein F. On the mechanism of ribonuclease A. Crystal and molecular structure of uridine 3'-O-thiophosphate methyl ester triethylammonium salt. European Journal of Biochemistry. 46: 559-67. PMID 4853455 DOI: 10.1111/J.1432-1033.1974.Tb03650.X  0.316
1974 Armstrong VW, Sternbach H, Eckstein F. Approaches to the affinity labelling of E. coli DNA-dependent RNA polymerase. Febs Letters. 44: 157-9. PMID 4608720 DOI: 10.1016/0014-5793(74)80715-5  0.3
1974 von Döbeln U, Eckstein F. Ribonucleoside 5'-thiodiphosphates as substrates for Escherichia coli ribonucleotide reductase. European Journal of Biochemistry. 43: 215-20. PMID 4151721 DOI: 10.1111/J.1432-1033.1974.Tb03402.X  0.311
1972 Goody RS, Eckstein F, Schirmer RH. The enzymatic synthesis of thiophosphate analogs of nucleotides. Biochimica Et Biophysica Acta. 276: 155-61. PMID 5065405 DOI: 10.1016/0005-2744(72)90016-2  0.33
1971 Goody RS, Eckstein F. Thiophosphate analogs of nucleoside di- and triphosphates Journal of the American Chemical Society. 93: 6252-6257. DOI: 10.1021/Ja00752A042  0.31
1968 Eckstein F, Gindl H. Synthesis of nucleoside 5'-polyphosphorothioates. Biochimica Et Biophysica Acta. 149: 35-40. PMID 5582754 DOI: 10.1016/0005-2787(67)90688-0  0.304
1968 Matzura H, Eckstein F. A polyribonucleotide containing alternation P=O and P=S linkages. European Journal of Biochemistry. 3: 448-52. PMID 4296031 DOI: 10.1111/J.1432-1033.1967.Tb19551.X  0.312
1966 Eckstein F. Synthesis of Oligodeoxynucleotides with Terminal 5′-Phosphate Groups Angewandte Chemie International Edition in English. 5: 671-672. DOI: 10.1002/Anie.196606713  0.314
1961 Helferich B, Piel W, Eckstein F. Zur Synthese von Glucosiden aus 1-Acyl-β-D-glucose-Derivaten Chemische Berichte. 94: 491-498. DOI: 10.1002/Cber.19610940231  0.475
1960 Helferich B, Eckstein F. Glykosidsynthesen aus 1-Mesitoyl-aldosen Chemische Berichte. 93: 2467-2469. DOI: 10.1002/Cber.19600931105  0.472
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