Artur A Indzhykulian - Publications

Affiliations: 
2009-2012 Physiology University of Kentucky, Lexington, KY 
 2012-2017 Neurobiology Harvard Medical School 
 2018- OHNS Harvard Medical School 
Website:
https://ailab.meei.harvard.edu/

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Strelkova OS, Osgood RT, Tian C, Zhang X, Hale E, De-la-Torre P, Hathaway DM, Indzhykulian AA. PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure. Communications Biology. 7: 1423. PMID 39482437 DOI: 10.1038/s42003-024-07121-5  0.388
2024 De-la-Torre P, Wen H, Brower J, Martínez-Pérez K, Narui Y, Yeh F, Hale E, Ivanchenko MV, Corey DP, Sotomayor M, Indzhykulian AA. Elasticity and Thermal Stability are Key Determinants of Hearing Rescue by Mini-Protocadherin-15 Proteins. Biorxiv : the Preprint Server For Biology. PMID 38948700 DOI: 10.1101/2024.06.16.599132  0.76
2024 De-la-Torre P, Martínez-García C, Gratias P, Mun M, Santana P, Akyuz N, González W, Indzhykulian AA, Ramírez D. Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1. Biorxiv : the Preprint Server For Biology. PMID 38826329 DOI: 10.1101/2024.03.05.583611  0.777
2024 Buswinka CJ, Rosenberg DB, Simikyan RG, Osgood RT, Fernandez K, Nitta H, Hayashi Y, Liberman LW, Nguyen E, Yildiz E, Kim J, Jarysta A, Renauld J, Wesson E, Wang H, ... ... Indzhykulian AA, et al. Large-scale annotated dataset for cochlear hair cell detection and classification. Scientific Data. 11: 416. PMID 38653806 DOI: 10.1038/s41597-024-03218-y  0.796
2024 Strelkova OS, Osgood RT, Tian CJ, Zhang X, Hale E, De-la-Torre P, Hathaway DM, Indzhykulian AA. PKHD1L1 is Required for Stereocilia Bundle Maintenance, Prolonged Hearing Function and Enhanced Resilience to Noise Exposure. Biorxiv : the Preprint Server For Biology. PMID 38496629 DOI: 10.1101/2024.02.29.582786  0.388
2024 Redfield SE, De-la-Torre P, Zamani M, Wang H, Khan H, Morris T, Shariati G, Karimi M, Kenna MA, Seo GH, Xu H, Lu W, Naz S, Galehdari H, Indzhykulian AA, et al. PKHD1L1, a gene involved in the stereocilia coat, causes autosomal recessive nonsyndromic hearing loss. Human Genetics. PMID 38459354 DOI: 10.1007/s00439-024-02649-2  0.31
2023 Redfield SE, De-la-Torre P, Zamani M, Khan H, Morris T, Shariati G, Karimi M, Kenna MA, Seo GH, Naz S, Galehdari H, Indzhykulian AA, Shearer AE, Vona B. , A Gene Involved in the Stereociliary Coat, Causes Autosomal Recessive Nonsyndromic Hearing Loss. Medrxiv : the Preprint Server For Health Sciences. PMID 37873491 DOI: 10.1101/2023.10.08.23296081  0.329
2023 Buswinka CJ, Rosenberg DB, Simikyan RG, Osgood RT, Fernandez K, Nitta H, Hayashi Y, Liberman LW, Nguyen E, Yildiz E, Kim J, Jarysta A, Renauld J, Wesson E, Thapa P, ... ... Indzhykulian AA, et al. Large-scale annotated dataset for cochlear hair cell detection and classification. Biorxiv : the Preprint Server For Biology. PMID 37693382 DOI: 10.1101/2023.08.30.553559  0.799
2023 Peters CW, Hanlon KS, Ivanchenko MV, Zinn E, Linarte EF, Li Y, Levy JM, Liu DR, Kleinstiver BP, Indzhykulian AA, Corey DP. Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37312453 DOI: 10.1016/j.ymthe.2023.06.007  0.6
2023 Ivanchenko MV, Hathaway DM, Klein AJ, Pan B, Strelkova O, De-la-Torre P, Wu X, Peters CW, Mulhall EM, Booth KT, Goldstein C, Brower J, Sotomayor M, Indzhykulian AA, Corey DP. Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F. Nature Communications. 14: 2400. PMID 37100771 DOI: 10.1038/s41467-023-38038-y  0.782
2023 Quan YZ, Wei W, Ergin V, Rameshbabu AP, Huang M, Tian C, Saladi SV, Indzhykulian AA, Chen ZY. Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2215253120. PMID 37068229 DOI: 10.1073/pnas.2215253120  0.337
2023 Buswinka CJ, Osgood RT, Simikyan RG, Rosenberg DB, Indzhykulian AA. The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification. Plos Biology. 21: e3002041. PMID 36947567 DOI: 10.1371/journal.pbio.3002041  0.372
2021 Ivanchenko MV, Indzhykulian AA, Corey DP. Electron Microscopy Techniques for Investigating Structure and Composition of Hair-Cell Stereociliary Bundles. Frontiers in Cell and Developmental Biology. 9: 744248. PMID 34746139 DOI: 10.3389/fcell.2021.744248  0.601
2021 Holmgren M, Ravicz ME, Hancock KE, Strelkova O, Kallogjeri D, Indzhykulian AA, Warchol ME, Sheets L. Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish. Elife. 10. PMID 34665127 DOI: 10.7554/eLife.69264  0.32
2021 Hayashi Y, Chiang H, Tian C, Indzhykulian AA, Edge ASB. Norrie disease protein is essential for cochlear hair cell maturation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34544869 DOI: 10.1073/pnas.2106369118  0.391
2020 Ivanchenko MV, Cicconet M, Jandal HA, Wu X, Corey DP, Indzhykulian AA. Serial scanning electron microscopy of anti-PKHD1L1 immuno-gold labeled mouse hair cell stereocilia bundles. Scientific Data. 7: 182. PMID 32555200 DOI: 10.1038/s41597-020-0509-4  0.584
2019 Shu Y, Li W, Huang M, Quan YZ, Scheffer D, Tian C, Tao Y, Liu X, Hochedlinger K, Indzhykulian AA, Wang Z, Li H, Chen ZY. Renewed proliferation in adult mouse cochlea and regeneration of hair cells. Nature Communications. 10: 5530. PMID 31797926 DOI: 10.1038/s41467-019-13157-7  0.379
2019 Wu X, Ivanchenko MV, Al Jandal H, Cicconet M, Indzhykulian AA, Corey DP. PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing. Nature Communications. 10: 3801. PMID 31444330 DOI: 10.1038/s41467-019-11712-w  0.623
2019 György B, Meijer EJ, Ivanchenko MV, Tenneson K, Emond F, Hanlon KS, Indzhykulian AA, Volak A, Karavitaki KD, Tamvakologos PI, Vezina M, Berezovskii VK, Born RT, O'Brien M, Lafond JF, et al. Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate. Molecular Therapy. Methods & Clinical Development. 13: 1-13. PMID 30581889 DOI: 10.1016/J.Omtm.2018.11.003  0.796
2017 Vélez-Ortega AC, Freeman MJ, Indzhykulian AA, Grossheim JM, Frolenkov GI. Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells. Elife. 6. PMID 28350294 DOI: 10.7554/Elife.24661  0.799
2017 Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS. Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c. Nature Biotechnology. PMID 28165476 DOI: 10.1038/Nbt.3801  0.792
2017 György B, Sage C, Indzhykulian AA, Scheffer DI, Brisson AR, Tan S, Wu X, Volak A, Mu D, Tamvakologos PI, Li Y, Fitzpatrick Z, Ericsson M, Breakefield XO, Corey DP, et al. Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28082074 DOI: 10.1016/J.Ymthe.2016.12.010  0.67
2016 Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing SJ, Vilardi F, Indzhykulian AA, Pangršič T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, et al. Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. The Embo Journal. PMID 27458190 DOI: 10.15252/Embj.201593565  0.79
2016 Wu X, Indzhykulian AA, Niksch PD, Webber RM, Garcia-Gonzalez M, Watnick T, Zhou J, Vollrath MA, Corey DP. Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice. Plos One. 11: e0155577. PMID 27196058 DOI: 10.1371/journal.pone.0155577  0.776
2016 Delling M, Indzhykulian AA, Liu X, Li Y, Xie T, Corey DP, Clapham DE. Primary cilia are not calcium-responsive mechanosensors. Nature. PMID 27007841 DOI: 10.1038/Nature17426  0.585
2015 Indzhykulian AA, Corey DP. In the Right Place at the Right Time: Is TMC1/2 the Transduction Channel for Hearing? Cell Reports. 12: 1531-2. PMID 26352665 DOI: 10.1016/j.celrep.2015.08.064  0.566
2015 Fang Q, Indzhykulian AA, Mustapha M, Riordan GP, Dolan DF, Friedman TB, Belyantseva IA, Frolenkov GI, Camper SA, Bird JE. The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing. Elife. 4. PMID 26302205 DOI: 10.7554/Elife.08627  0.691
2015 Scheffer DI, Zhang DS, Shen J, Indzhykulian A, Karavitaki KD, Xu YJ, Wang Q, Lin JJ, Chen ZY, Corey DP. XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia. Cell Reports. 10: 1811-8. PMID 25772365 DOI: 10.1016/J.Celrep.2015.02.042  0.8
2015 Gyorgy B, Sage C, Scheffer D, Indzhykulian AA, Mu D, Breakefield XO, Maguire CA, Corey DP. 16. Exosome-Associated AAV as a Novel Platform for Gene Therapy of Hearing Loss Molecular Therapy. 23: S7. DOI: 10.1016/S1525-0016(16)33620-6  0.627
2013 Indzhykulian AA, Stepanyan R, Nelina A, Spinelli KJ, Ahmed ZM, Belyantseva IA, Friedman TB, Barr-Gillespie PG, Frolenkov GI. Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells. Plos Biology. 11: e1001583. PMID 23776407 DOI: 10.1371/Journal.Pbio.1001583  0.811
2012 Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, Nandamuri SP, Yousaf R, Sinha GP, Lee S, Terrell D, Hegde RS, Ali RA, Anwar S, Andrade-Elizondo PB, Sirmaci A, et al. Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. Nature Genetics. 44: 1265-71. PMID 23023331 DOI: 10.1038/Ng.2426  0.683
2012 Velez-Ortega AC, Indzhykulian AA, Sinha GP, Frolenkov GI. Imaging Stereocilia Links in Live Auditory Hair Cells Biophysical Journal. 102: 655a. DOI: 10.1016/J.Bpj.2011.11.3567  0.772
2011 Stepanyan RS, Indzhykulian AA, Vélez-Ortega AC, Boger ET, Steyger PS, Friedman TB, Frolenkov GI. TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells. Journal of the Association For Research in Otolaryngology : Jaro. 12: 729-40. PMID 21879401 DOI: 10.1007/S10162-011-0288-X  0.809
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