| Year |
Citation |
Score |
| 2020 |
Zuo WL, Rostami MR, LeBlanc M, Kaner RJ, O'Beirne SL, Mezey JG, Leopold PL, Quast K, Visvanathan S, Fine JS, Thomas MJ, Crystal RG. Dysregulation of club cell biology in idiopathic pulmonary fibrosis. Plos One. 15: e0237529. PMID 32941426 DOI: 10.1371/Journal.Pone.0237529 |
0.394 |
|
| 2020 |
Sosulski ML, Stiles KM, Frenk EZ, Hart FM, Matsumura Y, De BP, Kaminsky SM, Crystal RG. Gene therapy for alpha 1-antitrypsin deficiency with an oxidant-resistant human alpha 1-antitrypsin. Jci Insight. 5. PMID 32759494 DOI: 10.1172/Jci.Insight.135951 |
0.322 |
|
| 2020 |
Zuo WL, Rostami MR, Shenoy SA, LeBlanc MG, Salit J, Strulovici-Barel Y, O'Beirne SL, Kaner RJ, Leopold PL, Mezey JG, Schymeinsky J, Quast K, Visvanathan S, Fine JS, Thomas MJ, ... Crystal RG, et al. Cell-specific expression of lung disease risk-related genes in the human small airway epithelium. Respiratory Research. 21: 200. PMID 32727470 DOI: 10.1186/S12931-020-01442-9 |
0.367 |
|
| 2020 |
Gindele JA, Kiechle T, Benediktus K, Birk G, Brendel M, Heinemann F, Wohnhaas CT, LeBlanc M, Zhang H, Strulovici-Barel Y, Crystal RG, Thomas MJ, Stierstorfer B, Quast K, Schymeinsky J. Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture. Scientific Reports. 10: 6257. PMID 32277131 DOI: 10.1038/S41598-020-63345-5 |
0.327 |
|
| 2019 |
O'Beirne SL, Kikkers SA, Oromendia C, Salit J, Rostmai MR, Ballman KV, Kaner RJ, Crystal RG, Cloonan SM. Alveolar Macrophage Immunometabolism and Lung Function Impairment in Smoking and Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 31751151 DOI: 10.1164/Rccm.201908-1683Le |
0.315 |
|
| 2019 |
Sacramento CB, Sondhi D, Rosenberg JB, Chen A, Giordano S, Pey E, Lee V, Stiles K, Havlicek D, Leopold P, Kaminsky SM, Crystal RG. Anti-phospho-tau Gene Therapy for Chronic Traumatic Encephalopathy. Human Gene Therapy. PMID 31608704 DOI: 10.1089/Hum.2019.174 |
0.302 |
|
| 2019 |
Wang G, Lou HH, Salit J, Leopold PL, Driscoll S, Schymeinsky J, Quast K, Visvanathan S, Fine JS, Thomas MJ, Crystal RG. Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity. Respiratory Research. 20: 196. PMID 31443657 DOI: 10.1186/S12931-019-1140-9 |
0.334 |
|
| 2019 |
Ogawa F, Walters MS, Shafquat A, O'Beirne SL, Kaner RJ, Mezey JG, Zhang H, Leopold PL, Crystal RG. Role of KRAS in regulating normal human airway basal cell differentiation. Respiratory Research. 20: 181. PMID 31399087 DOI: 10.1186/S12931-019-1129-4 |
0.301 |
|
| 2019 |
Zuo WL, Yang J, Strulovici-Barel Y, Salit J, Rostami M, Mezey JG, O'Beirne SL, Kaner RJ, Crystal RG. Exaggerated BMP4 Signalling Alters Human Airway Basal Progenitor Cell Differentiation to Cigarette Smoking-related Phenotypes. The European Respiratory Journal. PMID 30705127 DOI: 10.1183/13993003.02553-2017 |
0.322 |
|
| 2019 |
Rostami M, Zuo W, Crystal RG, Mezey JG. Cell-specific upregulation of lung “cancer signature genes” in the small airway epithelium of asymptomatic smokers. Journal of Clinical Oncology. 37: 3109-3109. DOI: 10.1200/Jco.2019.37.15_Suppl.3109 |
0.34 |
|
| 2018 |
Stiles KM, Sondhi D, Kaminsky SM, De BP, Rosenberg JB, Crystal RG. Intrapleural Gene Therapy for Alpha-1 Antitrypsin Deficiency-Related Lung Disease. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 5: 244-257. PMID 30723782 DOI: 10.15326/Jcopdf.5.4.2017.0160 |
0.364 |
|
| 2018 |
Qiu T, Chiuchiolo MJ, Whaley AS, Russo AR, Sondhi D, Kaminsky SM, Crystal RG, Pagovich OE. Gene Therapy for C1 Esterase Inhibitor Deficiency in a Murine Model of Hereditary Angioedema. Allergy. PMID 30059156 DOI: 10.1111/All.13582 |
0.31 |
|
| 2018 |
De BP, Chen A, Salami CO, Van De Graaf B, Rosenberg JB, Pagovich OE, Sondhi D, Crystal RG, Kaminsky SM. In Vivo Potency Assay for AAV-based Gene Therapy Vectors. Human Gene Therapy Methods. PMID 29706115 DOI: 10.1089/Hgtb.2017.246 |
0.316 |
|
| 2018 |
Markmann S, Reid J, Rosenberg JB, De BP, Kaminsky SM, Crystal RG, Sondhi D. Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2. Experimental Neurology. PMID 29655638 DOI: 10.1016/J.Expneurol.2018.04.001 |
0.328 |
|
| 2018 |
Zhang H, Yang J, Walters MS, Staudt MR, Strulovici-Barel Y, Salit J, Mezey JG, Leopold PL, Crystal RG. Mandatory role of HMGA1 in human airway epithelial normal differentiation and post-injury regeneration. Oncotarget. 9: 14324-14337. PMID 29581847 DOI: 10.18632/Oncotarget.24511 |
0.365 |
|
| 2018 |
Martinez FJ, Han MK, Allinson JP, Barr RG, Boucher RC, Calverley P, Celli BR, Christenson SA, Crystal RG, Fagerås M, Freeman CM, Groenke L, Hoffman EA, Kesimer M, Kostikas K, et al. At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 29406779 DOI: 10.1164/Rccm.201710-2028Pp |
0.344 |
|
| 2018 |
Markmann S, De BP, Reid J, Jose C, Rosenberg JB, Leopold P, Kaminsky SM, Sondhi D, Pagovich OE, Crystal RG. Biology of the Adrenal Gland Cortex Obviates Effective Use of Adeno-associated Virus Vectors to Treat Hereditary Adrenal Disorders. Human Gene Therapy. PMID 29316814 DOI: 10.1089/Hum.2017.203 |
0.343 |
|
| 2017 |
Wang G, Zhou H, Strulovici-Barel Y, Al-Hijji M, Ou X, Salit J, Walters MS, Staudt MR, Kaner RJ, Crystal RG. Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium. Autophagy. 0. PMID 28548877 DOI: 10.1080/15548627.2017.1301327 |
0.31 |
|
| 2017 |
Yang J, Zuo WL, Fukui T, Chao I, Gomi K, Lee B, Staudt MR, Kaner RJ, Strulovici-Barel Y, Salit J, Crystal RG, Shaykhiev R. Smoking-dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium. American Journal of Respiratory and Critical Care Medicine. PMID 28345955 DOI: 10.1164/Rccm.201608-1672Oc |
0.312 |
|
| 2017 |
Kothari P, De BP, He B, Chen A, Chiuchiolo MJ, Kim D, Nikolopoulou A, Amor-Coarasa A, Dyke JP, Voss HU, Kaminsky SM, Foley CP, Vallabhajosula S, Hu B, DiMagno SG, ... ... Crystal RG, et al. Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors. Scientific Reports. 7: 39594. PMID 28059103 DOI: 10.1038/Srep39594 |
0.327 |
|
| 2017 |
Gomi K, Tang Y, Arbelaez V, Crystal RG, Walters MS. Endothelial Cell Mediated Promotion of Ciliated Cell Differentiation of Human Airway Basal Cells via Insulin and Insulin-Like Growth Factor 1 Receptor Mediated Signaling. Stem Cell Reviews. PMID 28050756 DOI: 10.1007/S12015-016-9707-Z |
0.314 |
|
| 2016 |
Sondhi D, Stiles K, De BP, Crystal RG. Genetic Modification of the Lung Directed Toward Treatment of Human Disease. Human Gene Therapy. PMID 27927014 DOI: 10.1089/Hum.2016.152 |
0.368 |
|
| 2016 |
Hicks MJ, Chiuchiolo MJ, Ballon D, Dyke JP, Aronowitz E, Funato K, Tabar V, Havlicek D, Fan F, Sondhi D, Kaminsky SM, Crystal RG. Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma. Plos One. 11: e0162978. PMID 27711187 DOI: 10.1371/Journal.Pone.0162978 |
0.304 |
|
| 2016 |
Zuo WL, Yang J, Gomi K, Chao I, Crystal RG, Shaykhiev R. EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-induced Lesions in the Human Airway Epithelium. Stem Cells (Dayton, Ohio). PMID 27709733 DOI: 10.1002/Stem.2512 |
0.341 |
|
| 2016 |
Rosenberg JB, Kaminsky SM, Aubourg P, Crystal RG, Sondhi D. Gene therapy for metachromatic leukodystrophy. Journal of Neuroscience Research. 94: 1169-79. PMID 27638601 DOI: 10.1002/Jnr.23792 |
0.316 |
|
| 2016 |
Chiuchiolo MJ, Crystal RG. Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease. Annals of the American Thoracic Society. 13: S352-69. PMID 27564673 DOI: 10.1513/Annalsats.201506-344Kv |
0.349 |
|
| 2016 |
Strulovici-Barel Y, Staudt MR, Krause A, Gordon C, Tilley AE, Harvey BG, Kaner RJ, Hollmann C, Mezey JG, Bitter H, Pillai SG, Hilton H, Wolff G, Stevenson CS, Visvanathan S, ... ... Crystal RG, et al. Persistence of circulating endothelial microparticles in COPD despite smoking cessation. Thorax. PMID 27462120 DOI: 10.1136/Thoraxjnl-2015-208274 |
0.302 |
|
| 2016 |
Gomi K, Staudt MR, Salit J, Kaner RJ, Heldrich J, Rogalski AM, Arbelaez V, Crystal RG, Walters MS. JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium. Stem Cell Reviews. PMID 27216293 DOI: 10.1007/S12015-016-9656-6 |
0.302 |
|
| 2016 |
Zhou H, Brekman A, Zuo WL, Ou X, Shaykhiev R, Agosto-Perez FJ, Wang R, Walters MS, Salit J, Strulovici-Barel Y, Staudt MR, Kaner RJ, Mezey JG, Crystal RG, Wang G. POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes. Journal of Immunology (Baltimore, Md. : 1950). PMID 26927796 DOI: 10.4049/Jimmunol.1502400 |
0.374 |
|
| 2016 |
Tilley AE, Staudt MR, Salit J, Van de Graaf B, Strulovici-Barel Y, Kaner RJ, Vincent T, Agosto-Perez F, Mezey JG, Raby BA, Crystal RG. Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders. American Journal of Respiratory and Critical Care Medicine. 193: 215-217. PMID 26771416 DOI: 10.1164/Rccm.201412-2290Le |
0.329 |
|
| 2016 |
Pagovich OE, Qiu T, Whaley AS, Russo AR, Rosenberg J, De BP, Russo C, Chiuchiolo MJ, Sondhi D, Kaminsky SM, Crystal RG. 755. One-time Gene Therapy for Hereditary Angioedema Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33563-8 |
0.332 |
|
| 2016 |
Rosenberg JB, De BP, Quach L, Russo C, Kaminsky SM, Sondhi D, Crystal RG. 474. Consequences of Infusion Time on Efficiency of Intravenous Delivery of Vector Genomes to the Liver Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33283-X |
0.309 |
|
| 2016 |
De BP, Chen A, Rosenberg JB, Chiuchiolo M, Graaf BVd, Pagovich OE, Sondhi D, Russo C, Kaminsky SM, Crystal RG. 471. In Vivo Potency Assay for AAV-Based Gene Therapy Vectors Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33280-4 |
0.302 |
|
| 2015 |
Harvey BG, Strulovici-Barel Y, Kaner RJ, Sanders A, Vincent TL, Mezey JG, Crystal RG. Risk of COPD with obstruction in active smokers with normal spirometry and reduced diffusion capacity. The European Respiratory Journal. PMID 26541521 DOI: 10.1183/13993003.02377-2014 |
0.315 |
|
| 2015 |
Ding BS, Gomi K, Rafii S, Crystal RG, Walters MS. Endothelial MMP14 is required for endothelial dependent growth support of human airway basal cells. Journal of Cell Science. PMID 26116571 DOI: 10.1242/Dev.129791 |
0.302 |
|
| 2015 |
Zerah M, Piguet F, Colle MA, Raoul S, Deschamps JY, Deniaud J, Gautier B, Toulgoat F, Bieche I, Laurendeau I, Sondhi D, Souweidane MM, Cartier-Lacave N, Moullier P, Crystal RG, et al. Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates. Human Gene Therapy. Clinical Development. 26: 113-24. PMID 25758611 DOI: 10.1089/Humc.2014.139 |
0.322 |
|
| 2015 |
Hicks MJ, Funato K, Wang L, Aronowitz E, Dyke JP, Ballon DJ, Havlicek DF, Frenk EZ, De BP, Chiuchiolo MJ, Sondhi D, Hackett NR, Kaminsky SM, Tabar V, Crystal RG. Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma. Cancer Gene Therapy. 22: 1-8. PMID 25501993 DOI: 10.1038/Cgt.2014.58 |
0.321 |
|
| 2015 |
Durgan J, Tao G, Walters MS, Florey O, Schmidt A, Arbelaez V, Rosen N, Crystal RG, Hall A. SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1. Embo Reports. 16: 87-96. PMID 25394671 DOI: 10.15252/Embr.201439218 |
0.306 |
|
| 2015 |
Tilley AE, Walters MS, Shaykhiev R, Crystal RG. Cilia dysfunction in lung disease. Annual Review of Physiology. 77: 379-406. PMID 25386990 DOI: 10.1146/Annurev-Physiol-021014-071931 |
0.339 |
|
| 2015 |
Hunninghake GW, Kawanami O, Ferrans VJ, Young RC, Roberts WC, Crystal RG. Characterization of the Inflammatory and Immune Effector Cells in the Lung Parenchyma of Patients with Interstitial Lung Disease1,2 The American Review of Respiratory Disease. 123: 407. PMID 7224352 DOI: 10.1164/Arrd.1981.123.4.407 |
0.337 |
|
| 2015 |
Keogh BA, Bernardo J, Hunninghake GW, Line BR, Price DL, Crystal RG. Effect of Intermittent High Dose Parenteral Corticosteroids on the Alveolitis of Idiopathic Pulmonary Fibrosis1,2 The American Review of Respiratory Disease. 127: 18-22. PMID 6849542 DOI: 10.1164/Arrd.1983.127.1.18 |
0.327 |
|
| 2015 |
Rossi GA, Hunninghake GW, Gadek JE, Szapiel SV, Kawanami O, Ferrans VJ, Crystal RG. Hereditary emphysema in the tight-skin mouse. Evaluation of pathogenesis. The American Review of Respiratory Disease. 129: 850-855. PMID 6562869 DOI: 10.1164/Arrd.1984.129.5.850 |
0.348 |
|
| 2015 |
Langston C, Sachdeva P, Cowan MJ, Haines J, Crystal RG, Thurlbeck WM. Alveolar Multiplication in the Contralateral Lung after Unilateral Pneumonectomy in the Rabbit1–3 The American Review of Respiratory Disease. 115: 7-13. PMID 835893 DOI: 10.1164/Arrd.1977.115.1.7 |
0.302 |
|
| 2015 |
Kawanami O, Ferrans VJ, Crystal RG. Anchoring Fibrils in the Normal Canine Respiratory System1,2 The American Review of Respiratory Disease. 120: 595-611. PMID 484934 DOI: 10.1164/Arrd.1979.120.3.595 |
0.302 |
|
| 2015 |
Hunninghake GW, Fulmer JD, Young RC, Gadek JE, Crystal RG. Localization of the immune response in sarcoidosis. The American Review of Respiratory Disease. 120: 49-57. PMID 313729 DOI: 10.1164/Arrd.1979.120.1.49 |
0.337 |
|
| 2015 |
Szapiel SV, Elson NA, Fulmer JD, Hunninghake GW, Crystal RG. Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. The American Review of Respiratory Disease. 120: 893. PMID 92208 DOI: 10.1164/Arrd.1979.120.4.893 |
0.322 |
|
| 2015 |
Chiuchiolo MJ, Hicks MJ, Xie Y, Fan F, Rosenberg JB, Dyke JP, Funato K, Havlicek DF, Ballon DJ, Tabar V, Sondhi D, Kaminsky SM, Crystal RG. 718. AAV-Mediated Local Anti-EGFR Antibody Gene Expression in CNS Delays Tumor Growth and Increases Survival in a Human Glioblastoma Xenograft Model Molecular Therapy. 23: S287. DOI: 10.1016/S1525-0016(16)34327-1 |
0.311 |
|
| 2015 |
Kothari PJ, De BP, He B, Foley C, Chen A, Chiuchiolo MJ, Sondhi D, Kaminsky S, Babich J, Vallabajosula S, Crystal RG, Ballon D. 501. Radioiodinated Adeno-Associated Virus: A Promising New Approach for Monitoring Gene Therapy Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34110-7 |
0.303 |
|
| 2015 |
Pagovich OE, Wang B, Price CC, Jose C, Kaminsky SM, Chiuchiolo MJ, Crystal RG. 444. One-Time Gene Therapy to Prevent Peanut-Induced Anaphylaxis Molecular Therapy. 23: S176. DOI: 10.1016/S1525-0016(16)34053-9 |
0.32 |
|
| 2014 |
Shaykhiev R, Crystal RG. Early events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cells. Annals of the American Thoracic Society. 11: S252-8. PMID 25525728 DOI: 10.1513/Annalsats.201402-049Aw |
0.35 |
|
| 2014 |
Crystal RG. Airway basal cells. The "smoking gun" of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 190: 1355-62. PMID 25354273 DOI: 10.1164/Rccm.201408-1492Pp |
0.328 |
|
| 2014 |
Walters MS, De BP, Salit J, Buro-Auriemma LJ, Wilson T, Rogalski AM, Lief L, Hackett NR, Staudt MR, Tilley AE, Harvey BG, Kaner RJ, Mezey JG, Ashbridge B, Moore MA, ... Crystal RG, et al. Smoking accelerates aging of the small airway epithelium. Respiratory Research. 15: 94. PMID 25248511 DOI: 10.1186/S12931-014-0094-1 |
0.303 |
|
| 2014 |
Brekman A, Walters MS, Tilley AE, Crystal RG. FOXJ1 prevents cilia growth inhibition by cigarette smoke in human airway epithelium in vitro. American Journal of Respiratory Cell and Molecular Biology. 51: 688-700. PMID 24828273 DOI: 10.1165/Rcmb.2013-0363Oc |
0.322 |
|
| 2014 |
Ryan DM, Vincent TL, Salit J, Walters MS, Agosto-Perez F, Shaykhiev R, Strulovici-Barel Y, Downey RJ, Buro-Auriemma LJ, Staudt MR, Hackett NR, Mezey JG, Crystal RG. Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. Plos One. 9: e88051. PMID 24498427 DOI: 10.1371/Journal.Pone.0088051 |
0.328 |
|
| 2014 |
Hessel J, Heldrich J, Fuller J, Staudt MR, Radisch S, Hollmann C, Harvey BG, Kaner RJ, Salit J, Yee-Levin J, Sridhar S, Pillai S, Hilton H, Wolff G, Bitter H, ... ... Crystal RG, et al. Intraflagellar transport gene expression associated with short cilia in smoking and COPD. Plos One. 9: e85453. PMID 24465567 DOI: 10.1371/Journal.Pone.0085453 |
0.313 |
|
| 2014 |
Crystal RG. Adenovirus: the first effective in vivo gene delivery vector. Human Gene Therapy. 25: 3-11. PMID 24444179 DOI: 10.1089/Hum.2013.2527 |
0.312 |
|
| 2014 |
Sondhi D, Scott EC, Chen A, Hackett NR, Wong AM, Kubiak A, Nelvagal HR, Pearse Y, Cotman SL, Cooper JD, Crystal RG. Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene. Human Gene Therapy. 25: 223-39. PMID 24372003 DOI: 10.1089/Hum.2012.253 |
0.31 |
|
| 2014 |
Shaykhiev R, Crystal RG. Basal cell origins of smoking-induced airway epithelial disorders. Cell Cycle (Georgetown, Tex.). 13: 341-2. PMID 24335435 DOI: 10.4161/Cc.27510 |
0.366 |
|
| 2013 |
Reardon BJ, Hansen JG, Crystal RG, Houston DK, Kritchevsky SB, Harris T, Lohman K, Liu Y, O'Connor GT, Wilk JB, Mezey J, Gao C, Cassano PA. Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. Bmc Medical Genetics. 14: 122. PMID 24274704 DOI: 10.1186/1471-2350-14-122 |
0.341 |
|
| 2013 |
Kaminsky SM, Rosengart TK, Rosenberg J, Chiuchiolo MJ, Van de Graaf B, Sondhi D, Crystal RG. Gene therapy to stimulate angiogenesis to treat diffuse coronary artery disease. Human Gene Therapy. 24: 948-63. PMID 24164242 DOI: 10.1089/Hum.2013.2516 |
0.31 |
|
| 2013 |
Harvey BG, Strulovici-Barel Y, Vincent TL, Mezey JG, Raviram R, Gordon C, Salit J, Tilley AE, Chung A, Sanders A, Crystal RG. High correlation of the response of upper and lower lobe small airway epithelium to smoking. Plos One. 8: e72669. PMID 24039793 DOI: 10.1371/Journal.Pone.0072669 |
0.307 |
|
| 2013 |
Shaykhiev R, Crystal RG. Innate immunity and chronic obstructive pulmonary disease: a mini-review. Gerontology. 59: 481-9. PMID 24008598 DOI: 10.1159/000354173 |
0.328 |
|
| 2013 |
Agler AH, Crystal RG, Mezey JG, Fuller J, Gao C, Hansen JG, Cassano PA. Differential expression of vitamin E and selenium-responsive genes by disease severity in chronic obstructive pulmonary disease. Copd. 10: 450-8. PMID 23875740 DOI: 10.3109/15412555.2012.761958 |
0.333 |
|
| 2013 |
Shaykhiev R, Wang R, Zwick RK, Hackett NR, Leung R, Moore MA, Sima CS, Chao IW, Downey RJ, Strulovici-Barel Y, Salit J, Crystal RG. Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer. Stem Cells (Dayton, Ohio). 31: 1992-2002. PMID 23857717 DOI: 10.1002/Stem.1459 |
0.361 |
|
| 2013 |
Didon L, Zwick RK, Chao IW, Walters MS, Wang R, Hackett NR, Crystal RG. RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium. Respiratory Research. 14: 70. PMID 23822649 DOI: 10.1186/1465-9921-14-70 |
0.357 |
|
| 2013 |
Shaykhiev R, Zuo WL, Chao I, Fukui T, Witover B, Brekman A, Crystal RG. EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype. Proceedings of the National Academy of Sciences of the United States of America. 110: 12102-7. PMID 23818594 DOI: 10.1073/Pnas.1303058110 |
0.317 |
|
| 2013 |
Fukui T, Shaykhiev R, Agosto-Perez F, Mezey JG, Downey RJ, Travis WD, Crystal RG. Lung adenocarcinoma subtypes based on expression of human airway basal cell genes. The European Respiratory Journal. 42: 1332-44. PMID 23645403 DOI: 10.1183/09031936.00144012 |
0.37 |
|
| 2013 |
Krause A, Whu WZ, Qiu J, Wafadari D, Hackett NR, Sharma A, Crystal RG, Worgall S. RGD capsid modification enhances mucosal protective immunity of a non-human primate adenovirus vector expressing Pseudomonas aeruginosa OprF. Clinical and Experimental Immunology. 173: 230-41. PMID 23607394 DOI: 10.1111/Cei.12101 |
0.332 |
|
| 2013 |
Shaykhiev R, Sackrowitz R, Fukui T, Zuo WL, Chao IW, Strulovici-Barel Y, Downey RJ, Crystal RG. Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer. American Journal of Respiratory Cell and Molecular Biology. 49: 418-25. PMID 23597004 DOI: 10.1165/Rcmb.2012-0396Oc |
0.359 |
|
| 2013 |
Wewers MD, Crystal RG. Alpha-1 antitrypsin augmentation therapy. Copd. 10: 64-7. PMID 23527997 DOI: 10.3109/15412555.2013.764402 |
0.341 |
|
| 2013 |
Hansel NN, Ruczinski I, Rafaels N, Sin DD, Daley D, Malinina A, Huang L, Sandford A, Murray T, Kim Y, Vergara C, Heckbert SR, Psaty BM, Li G, Elliott WM, ... ... Crystal RG, et al. Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD. Human Genetics. 132: 79-90. PMID 22986903 DOI: 10.1007/S00439-012-1219-6 |
0.317 |
|
| 2012 |
Wang R, Ahmed J, Wang G, Hassan I, Strulovici-Barel Y, Salit J, Mezey JG, Crystal RG. Airway epithelial expression of TLR5 is downregulated in healthy smokers and smokers with chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 189: 2217-25. PMID 22855713 DOI: 10.4049/Jimmunol.1101895 |
0.315 |
|
| 2012 |
Wang G, Xu Z, Wang R, Al-Hijji M, Salit J, Strulovici-Barel Y, Tilley AE, Mezey JG, Crystal RG. Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers. Bmc Medical Genomics. 5: 21. PMID 22676183 DOI: 10.1186/1755-8794-5-21 |
0.369 |
|
| 2012 |
Crystal RG. The challenge of using gene- or cell-based therapies to treat lung disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1077-8. PMID 22652992 DOI: 10.1038/Mt.2012.91 |
0.359 |
|
| 2012 |
Piguet F, Sondhi D, Piraud M, Fouquet F, Hackett NR, Ahouansou O, Vanier MT, Bieche I, Aubourg P, Crystal RG, Cartier N, Sevin C. Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice. Human Gene Therapy. 23: 903-14. PMID 22642214 DOI: 10.1089/Hum.2012.015 |
0.322 |
|
| 2012 |
Wang L, Rosenberg JB, De BP, Ferris B, Wang R, Rivella S, Kaminsky SM, Crystal RG. In vivo gene transfer strategies to achieve partial correction of von Willebrand disease. Human Gene Therapy. 23: 576-88. PMID 22482515 DOI: 10.1089/Hum.2011.238 |
0.356 |
|
| 2012 |
Curradi G, Walters MS, Ding BS, Rafii S, Hackett NR, Crystal RG. Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cellular and Molecular Life Sciences : Cmls. 69: 2217-31. PMID 22382924 DOI: 10.1007/S00018-012-0922-8 |
0.333 |
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| 2012 |
Hackett NR, Butler MW, Shaykhiev R, Salit J, Omberg L, Rodriguez-Flores JL, Mezey JG, Strulovici-Barel Y, Wang G, Didon L, Crystal RG. RNA-Seq quantification of the human small airway epithelium transcriptome. Bmc Genomics. 13: 82. PMID 22375630 DOI: 10.1186/1471-2164-13-82 |
0.304 |
|
| 2012 |
Shaykhiev R, Fukui T, Crystal RG. Abstract B33: Identification of the Early Molecular Cancerization Features in the Airway Epithelium of Smokers without Cancer Clinical Cancer Research. 18. DOI: 10.1158/1078-0432.12Aacriaslc-B33 |
0.343 |
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| 2011 |
Ding BS, Nolan DJ, Guo P, Babazadeh AO, Cao Z, Rosenwaks Z, Crystal RG, Simons M, Sato TN, Worgall S, Shido K, Rabbany SY, Rafii S. Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell. 147: 539-53. PMID 22036563 DOI: 10.1016/J.Cell.2011.10.003 |
0.344 |
|
| 2011 |
Hackett NR, Shaykhiev R, Walters MS, Wang R, Zwick RK, Ferris B, Witover B, Salit J, Crystal RG. The human airway epithelial basal cell transcriptome. Plos One. 6: e18378. PMID 21572528 DOI: 10.1371/Journal.Pone.0018378 |
0.35 |
|
| 2011 |
Gordon C, Gudi K, Krause A, Sackrowitz R, Harvey BG, Strulovici-Barel Y, Mezey JG, Crystal RG. Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers. American Journal of Respiratory and Critical Care Medicine. 184: 224-32. PMID 21471087 DOI: 10.1164/Rccm.201012-2061Oc |
0.306 |
|
| 2011 |
Butler MW, Hackett NR, Salit J, Strulovici-Barel Y, Omberg L, Mezey J, Crystal RG. Glutathione S-transferase copy number variation alters lung gene expression. The European Respiratory Journal. 38: 15-28. PMID 21349909 DOI: 10.1183/09031936.00029210 |
0.356 |
|
| 2011 |
Butler MW, Fukui T, Salit J, Shaykhiev R, Mezey JG, Hackett NR, Crystal RG. Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer. Cancer Research. 71: 2572-81. PMID 21325429 DOI: 10.1158/0008-5472.Can-10-2046 |
0.353 |
|
| 2011 |
Krause A, Whu WZ, Xu Y, Joh J, Crystal RG, Worgall S. Protective anti-Pseudomonas aeruginosa humoral and cellular mucosal immunity by AdC7-mediated expression of the P. aeruginosa protein OprF. Vaccine. 29: 2131-9. PMID 21215829 DOI: 10.1016/J.Vaccine.2010.12.087 |
0.358 |
|
| 2011 |
Shaykhiev R, Otaki F, Bonsu P, Dang DT, Teater M, Strulovici-Barel Y, Salit J, Harvey BG, Crystal RG. Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo. Cellular and Molecular Life Sciences : Cmls. 68: 877-92. PMID 20820852 DOI: 10.1007/S00018-010-0500-X |
0.313 |
|
| 2011 |
Dvorak A, Tilley AE, Shaykhiev R, Wang R, Crystal RG. Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome? American Journal of Respiratory Cell and Molecular Biology. 44: 465-73. PMID 20525805 DOI: 10.1165/Rcmb.2009-0453Oc |
0.352 |
|
| 2011 |
Fukui T, Shaykhiev R, Wang R, Zwick RK, Hackett NR, Downey RJ, Crystal RG. Abstract 4721: Airway basal cell signature predicts aggressive phenotype of human lung adenocarcinoma Cancer Research. 71: 4721-4721. DOI: 10.1158/1538-7445.Am2011-4721 |
0.33 |
|
| 2010 |
Wang R, Wang G, Ricard MJ, Ferris B, Strulovici-Barel Y, Salit J, Hackett NR, Gudas LJ, Crystal RG. Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals. Chest. 138: 1402-10. PMID 20705797 DOI: 10.1378/Chest.09-2634 |
0.343 |
|
| 2010 |
Watanabe M, Boyer JL, Crystal RG. AAVrh.10-mediated genetic delivery of bevacizumab to the pleura to provide local anti-VEGF to suppress growth of metastatic lung tumors. Gene Therapy. 17: 1042-51. PMID 20596059 DOI: 10.1038/Gt.2010.87 |
0.342 |
|
| 2010 |
Wang G, Qiu J, Wang R, Krause A, Boyer JL, Hackett NR, Crystal RG. Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer. Cancer Gene Therapy. 17: 559-70. PMID 20448672 DOI: 10.1038/Cgt.2010.11 |
0.321 |
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| 2010 |
Van Blarcom TJ, Sofer-Podesta C, Ang J, Boyer JL, Crystal RG, Georgiou G. Affinity maturation of an anti-V antigen IgG expressed in situ through adenovirus gene delivery confers enhanced protection against Yersinia pestis challenge. Gene Therapy. 17: 913-21. PMID 20393511 DOI: 10.1038/Gt.2010.42 |
0.311 |
|
| 2010 |
Shaykhiev R, Wang R, Zwick R, Hackett N, Leung R, Moore MAS, Downey RJ, Strulovici-Barel Y, Salit J, Crystal R. Abstract LB-250: Smoking reprograms human airway basal cells in vivo toward an embryonic stem cell-like molecular phenotype similar to that of lung adenocarcinoma Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-250 |
0.379 |
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| 2009 |
Saitoh H, Leopold PL, Harvey BG, O'Connor TP, Worgall S, Hackett NR, Crystal RG. Emphysema mediated by lung overexpression of ADAM10. Clinical and Translational Science. 2: 50-6. PMID 20443867 DOI: 10.1111/J.1752-8062.2008.00085.X |
0.386 |
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| 2009 |
Leopold PL, O'Mahony MJ, Lian XJ, Tilley AE, Harvey BG, Crystal RG. Smoking is associated with shortened airway cilia. Plos One. 4: e8157. PMID 20016779 DOI: 10.1371/Journal.Pone.0008157 |
0.315 |
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| 2009 |
Shaykhiev R, Krause A, Salit J, Strulovici-Barel Y, Harvey BG, O'Connor TP, Crystal RG. Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 2867-83. PMID 19635926 DOI: 10.4049/Jimmunol.0900473 |
0.32 |
|
| 2009 |
Hübner RH, Schwartz JD, De Bishnu P, Ferris B, Omberg L, Mezey JG, Hackett NR, Crystal RG. Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking. Molecular Medicine (Cambridge, Mass.). 15: 203-19. PMID 19593404 DOI: 10.2119/Molmed.2008.00130 |
0.324 |
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| 2009 |
Xu Y, Tertilt C, Krause A, Quadri LE, Crystal RG, Worgall S. Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells. Respiratory Research. 10: 26. PMID 19344509 DOI: 10.1186/1465-9921-10-26 |
0.32 |
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| 2009 |
Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG. Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing. Human Gene Therapy. 20: 267-81. PMID 19257851 DOI: 10.1089/Hum.2008.173 |
0.325 |
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| 2009 |
Watanabe M, Boyer JL, Crystal RG. Genetic delivery of bevacizumab to suppress vascular endothelial growth factor-induced high-permeability pulmonary edema. Human Gene Therapy. 20: 598-610. PMID 19254174 DOI: 10.1089/Hum.2008.169 |
0.347 |
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| 2009 |
Vanni H, Kazeros A, Wang R, Harvey BG, Ferris B, De BP, Carolan BJ, Hübner RH, O'Connor TP, Crystal RG. Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human. Chest. 135: 1197-208. PMID 19188554 DOI: 10.1378/Chest.08-1024 |
0.312 |
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| 2009 |
Sofer-Podesta C, Ang J, Hackett NR, Senina S, Perlin D, Crystal RG, Boyer JL. Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge. Infection and Immunity. 77: 1561-8. PMID 19124600 DOI: 10.1128/Iai.00856-08 |
0.311 |
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| 2009 |
Tilley AE, Harvey BG, Heguy A, Hackett NR, Wang R, O'Connor TP, Crystal RG. Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 179: 457-66. PMID 19106307 DOI: 10.1164/Rccm.200705-795Oc |
0.357 |
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| 2009 |
Yin LH, Fu SQ, Nanakorn T, Garcia-Sanchez F, Chung I, Cote RJ, Pizzorno G, Hanania E, Heimfeld S, Crystal R, Deisseroth A. Results of retroviral and adenoviral approaches to cancer gene therapy. Stem Cells. 16: 247-250. PMID 11012168 DOI: 10.1002/Stem.5530160830 |
0.308 |
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| 2009 |
Song Y, Lou H, Boyer J, Limberis M, Vandenberghe L, Hackett N, Leopold P, Wilson J, Crystal R. Functional CFTR Expression in Cystic Fibrosis Airway Epithelial Cells by AAV6.2-mediated Segmental Trans-splicing Human Gene Therapy. 90205172040003. DOI: 10.1089/Hgt.2008.173 |
0.317 |
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| 2008 |
Carolan BJ, Harvey BG, De BP, Vanni H, Crystal RG. Decreased expression of intelectin 1 in the human airway epithelium of smokers compared to nonsmokers. Journal of Immunology (Baltimore, Md. : 1950). 181: 5760-7. PMID 18832735 DOI: 10.4049/Jimmunol.181.8.5760 |
0.325 |
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| 2008 |
Kazeros A, Harvey BG, Carolan BJ, Vanni H, Krause A, Crystal RG. Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokers. American Journal of Respiratory Cell and Molecular Biology. 39: 747-57. PMID 18587056 DOI: 10.1165/Rcmb.2007-0306Oc |
0.318 |
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| 2008 |
Skaricic D, Traube C, De B, Joh J, Boyer J, Crystal RG, Worgall S. Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV. Virology. 378: 79-85. PMID 18556039 DOI: 10.1016/J.Virol.2008.04.016 |
0.304 |
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| 2007 |
Worgall S, Krause A, Qiu J, Joh J, Hackett NR, Crystal RG. Protective immunity to pseudomonas aeruginosa induced with a capsid-modified adenovirus expressing P. aeruginosa OprF. Journal of Virology. 81: 13801-8. PMID 17942539 DOI: 10.1128/Jvi.01246-07 |
0.317 |
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| 2007 |
Strulovici Y, Leopold PL, O'Connor TP, Pergolizzi RG, Crystal RG. Human embryonic stem cells and gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 850-66. PMID 17356540 DOI: 10.1038/Mt.Sj.6300125 |
0.339 |
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| 2007 |
Sondhi D, Hackett NR, Peterson DA, Stratton J, Baad M, Travis KM, Wilson JM, Crystal RG. Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 481-91. PMID 17180118 DOI: 10.1038/Sj.Mt.6300049 |
0.318 |
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| 2007 |
Heguy A, Harvey BG, Leopold PL, Dolgalev I, Raman T, Crystal RG. Responses of the human airway epithelium transcriptome to in vivo injury Physiological Genomics. 29: 139-148. PMID 17164391 DOI: 10.1152/Physiolgenomics.00167.2006 |
0.335 |
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| 2006 |
Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, Crystal RG. Modification of gene expression of the small airway epithelium in response to cigarette smoking. Journal of Molecular Medicine. 85: 39-53. PMID 17115125 DOI: 10.1007/S00109-006-0103-Z |
0.357 |
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| 2006 |
Carolan BJ, Heguy A, Harvey BG, Leopold PL, Ferris B, Crystal RG. Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers Cancer Research. 66: 10729-10740. PMID 17108109 DOI: 10.1158/0008-5472.Can-06-2224 |
0.361 |
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| 2006 |
Chiuchiolo MJ, Boyer JL, Krause A, Senina S, Hackett NR, Crystal RG. Protective immunity against respiratory tract challenge with Yersinia pestis in mice immunized with an adenovirus-based vaccine vector expressing V antigen. The Journal of Infectious Diseases. 194: 1249-57. PMID 17041851 DOI: 10.1086/507644 |
0.318 |
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| 2006 |
Leopold PL, Wendland RL, Vincent T, Crystal RG. Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway Journal of Virology. 80: 10237-10247. PMID 17005701 DOI: 10.1128/Jvi.00512-06 |
0.339 |
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| 2006 |
Pergolizzi RG, Jin G, Chan D, Pierre L, Bussel J, Ferris B, Leopold PL, Crystal RG. Correction of a murine model of von Willebrand disease by gene transfer Blood. 108: 862-869. PMID 16638935 DOI: 10.1182/Blood-2005-06-2330 |
0.332 |
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| 2006 |
Heguy A, O'Connor TP, Luettich K, Worgall S, Cieciuch A, Harvey BG, Hackett NR, Crystal RG. Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking. Journal of Molecular Medicine (Berlin, Germany). 84: 318-28. PMID 16520944 DOI: 10.1007/S00109-005-0008-2 |
0.333 |
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| 2006 |
Zhu W, Kim J, Cheng C, Rawlins BA, Boachie-Adjei O, Crystal RG, Hidaka C. Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro Bone. 39: 61-71. PMID 16488673 DOI: 10.1016/J.Bone.2005.12.018 |
0.315 |
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| 2006 |
Passini MA, Dodge JC, Bu J, Yang W, Zhao Q, Sondhi D, Hackett NR, Kaminsky SM, Mao Q, Shihabuddin LS, Cheng SH, Sleat DE, Stewart GR, Davidson BL, Lobel P, ... Crystal RG, et al. Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1334-42. PMID 16452657 DOI: 10.1523/Jneurosci.2676-05.2006 |
0.309 |
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| 2006 |
De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG. High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 67-76. PMID 16260185 DOI: 10.1016/J.Ymthe.2005.09.003 |
0.358 |
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| 2006 |
Traube C, Heguy A, De B, Krause A, Wilson JM, Crystal RG, Worgall S. 779. Genetic Delivery of an Anti-RSV Antibody Protects Against Pulmonary Infection with RSV in Mice Molecular Therapy. 13: S301-S302. DOI: 10.1016/J.Ymthe.2006.08.866 |
0.341 |
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| 2006 |
De BP, Hackett NR, Qiu JP, Boyer JL, Wilson JM, Crystal RG. 611. Induction of Persistent Passive Immunity Against Anthrax Toxin by an Adeno-Associated Virus Type rh10 Vector Expressing Anti-Protective Antigen Antibody Molecular Therapy. 13: S236. DOI: 10.1016/J.Ymthe.2006.08.685 |
0.308 |
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| 2006 |
Jung J, Kim J, Pergolizzi RG, Crystal RG. 448. Suicide Gene-Mediated Conditional Ablation of Tumors Derived from Transplanted Embryonic Stem Cells Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.516 |
0.326 |
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| 2006 |
Hübner R, Kiuru M, Krause A, Rivella S, Pergolizzi RG, Crystal RG. 341. Lentivirus Transduction of Murine Embryonic Stem Cells with Truncated Human Low-Affinity Nerve Growth Factor Permits Efficient Purification of Genetically Modified Cells without Loss of Stem Cell Characteristics Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.399 |
0.346 |
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| 2006 |
Boyer JL, Kasuya K, Howard J, Hackett NR, Wilson JM, Crystal RG. 1101. Rapid and Long-Term Protection Against Anthrax Lethal Toxin Molecular Therapy. 13: S423. DOI: 10.1016/J.Ymthe.2006.08.1205 |
0.301 |
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| 2006 |
Krause A, Joh J, Gess A, Lou H, Crystal RG, Worgall S. 93. Increased Number of Lung CD34+ Sca-1+ Putative Stem Cells Mediated by Adenovirus Overexpression by Sonic Hedgehog in the Respiratory Tract of Adult Mice Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.112 |
0.363 |
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| 2005 |
Hashimoto M, Boyer JL, Hackett NR, Wilson JM, Crystal RG. Induction of protective immunity to anthrax lethal toxin with a nonhuman primate adenovirus-based vaccine in the presence of preexisting anti-human adenovirus immunity. Infection and Immunity. 73: 6885-91. PMID 16177368 DOI: 10.1128/Iai.73.10.6885-6891.2005 |
0.305 |
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| 2005 |
Mae M, O'Connor TP, Crystal RG. Gene transfer of the vascular endothelial growth factor receptor flt-1 suppresses pulmonary metastasis associated with lung growth. American Journal of Respiratory Cell and Molecular Biology. 33: 629-35. PMID 16151052 DOI: 10.1165/Rcmb.2005-0092Oc |
0.347 |
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| 2005 |
Sondhi D, Peterson DA, Giannaris EL, Sanders CT, Mendez BS, De B, Rostkowski AB, Blanchard B, Bjugstad K, Sladek JR, Redmond DE, Leopold PL, Kaminsky SM, Hackett NR, Crystal RG. AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL. Gene Therapy. 12: 1618-32. PMID 16052206 DOI: 10.1038/Sj.Gt.3302549 |
0.329 |
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| 2005 |
Worgall S, Heguy A, Luettich K, O'Connor TP, Harvey BG, Quadri LE, Crystal RG. Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia. Infection and Immunity. 73: 5262-8. PMID 16041053 DOI: 10.1128/Iai.73.8.5262-5268.2005 |
0.323 |
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| 2005 |
Amano H, Hackett NR, Kaner RJ, Whitlock P, Rosengart TK, Crystal RG. Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy Molecular Therapy. 12: 716-724. PMID 16039163 DOI: 10.1016/J.Ymthe.2005.03.031 |
0.307 |
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| 2005 |
Ware LB, Kaner RJ, Crystal RG, Schane R, Trivedi NN, McAuley D, Matthay MA. VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedama European Respiratory Journal. 26: 101-105. PMID 15994395 DOI: 10.1183/09031936.05.00106604 |
0.313 |
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| 2005 |
Worgall S, Krause A, Rivara M, Hee KK, Vintayen EV, Hackett NR, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG. Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid. The Journal of Clinical Investigation. 115: 1281-9. PMID 15841217 DOI: 10.1172/Jci23135 |
0.324 |
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| 2005 |
Zhang F, Cheng J, Lam G, Jin DK, Vincent L, Hackett NR, Wang S, Young LM, Hempstead B, Crystal RG, Rafii S. Adenovirus vector E4 gene regulates connexin 40 and 43 expression in endothelial cells via PKA and PI3K signal pathways. Circulation Research. 96: 950-7. PMID 15831817 DOI: 10.1161/01.Res.0000165867.95291.7B |
0.307 |
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| 2005 |
Kasuya K, Boyer JL, Tan Y, Alipui DO, Hackett NR, Crystal RG. Passive immunotherapy for anthrax toxin mediated by an adenovirus expressing an anti-protective antigen single-chain antibody. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 237-44. PMID 15668135 DOI: 10.1016/J.Ymthe.2004.10.018 |
0.318 |
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| 2005 |
Worgall S, Qiu J, Krause A, Kim K, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG. 975. Immunization with an Adenovirus Vector Expressing a P. aeruginosa OprF Epitope in the Capsid Enables Boosting of Anti-Epitope Immune Responses and Protects Against Pulmonary Infection with P. aeruginosa Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.518 |
0.327 |
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| 2005 |
Boyer JL, Howard J, Hackett NR, Pergolizzi RG, Wilson JM, Crystal RG. 853. Persistent Expression of Single Chain Antibodies Mediated by AAV5 and AAVrh.10 Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.396 |
0.333 |
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| 2005 |
Gelbman BD, Heguy A, O'Connor TP, Zabner J, Crystal RG. 814. Adenovirus-Mediated Gene Transfer Demonstrates That Pirin, a Transcription Factor Up-Regulated in the Bronchial Epithelium by Cigarette Smoke, Mediates Bronchial Epithelial Cell Apoptosis Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.351 |
0.375 |
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| 2005 |
Sondhi D, Peterson DA, Vassallo E, Sanders CT, Stratton JA, Hackett NR, Gao G, Wilson JM, Crystal RG. 660. Quantitative Comparison of AAV Serotypes AAV2, AAV5, and AAVrh.10 Efficiency for CNS Gene Therapy Following Intracranial Gene Delivery Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.200 |
0.35 |
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| 2005 |
Harvey B, De BP, Ayala JP, Hackett NR, Heguy A, Crystal R. 367. Safety and Immunological Responses Following Intrapleural Administration of an AAV5 Vector Encoding Human |[alpha]|1-Antitrypsin to Non-Human Primates Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.370 |
0.314 |
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| 2005 |
Pergolizzi RG, Guang J, Chan D, Wagner D, Lenting P, Crystal RG. 335. Correction of a Murine Model of Von Willebrand Disease by Gene Transfer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.338 |
0.338 |
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| 2004 |
Tomashefski JF, Crystal RG, Wiedemann HP, Mascha E, Stoller JK. The bronchopulmonary pathology of alpha-1 antitrypsin (AAT) deficiency: findings of the Death Review Committee of the national registry for individuals with Severe Deficiency of Alpha-1 Antitrypsin. Human Pathology. 35: 1452-1461. PMID 15619203 DOI: 10.1016/J.Humpath.2004.08.013 |
0.329 |
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| 2004 |
Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D, Dinner M, Wisniewski K, Kaplitt M, Greenwald BM, Howell JD, et al. Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis. Human Gene Therapy. 15: 1131-54. PMID 15610613 DOI: 10.1089/Hum.2004.15.1131 |
0.328 |
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| 2004 |
De B, Heguy A, Leopold PL, Wasif N, Korst RJ, Hackett NR, Crystal RG. Intrapleural administration of a serotype 5 adeno-associated virus coding for α1-antitrypsin mediates persistent, high lung and serum levels of α1-antitrypsin Molecular Therapy. 10: 1003-1010. PMID 15564132 DOI: 10.1016/J.Ymthe.2004.08.022 |
0.308 |
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| 2004 |
Zhu W, Rawlins BA, Boachie-Adjei O, Myers ER, Arimizu J, Choi E, Lieberman JR, Crystal RG, Hidaka C. Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model Journal of Bone and Mineral Research. 19: 2021-2032. PMID 15537446 DOI: 10.1359/Jbmr.040821 |
0.311 |
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| 2004 |
Pergolizzi RG, Crystal RG. Genetic medicine at the RNA level: modifications of the genetic repertoire for therapeutic purposes by pre-mRNA trans-splicing. Comptes Rendus Biologies. 327: 695-709. PMID 15506518 DOI: 10.1016/J.Crvi.2004.05.008 |
0.314 |
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| 2004 |
Hogan RJ, Gao G, Rowe T, Bell P, Flieder D, Paragas J, Kobinger GP, Wivel NA, Crystal RG, Boyer J, Feldmann H, Voss TG, Wilson JM. Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1. Journal of Virology. 78: 11416-21. PMID 15452265 DOI: 10.1128/Jvi.78.20.11416-11421.2004 |
0.32 |
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| 2004 |
Merritt RE, Yamada RE, Wasif N, Crystal RG, Korst RJ. Effect of inhibition of multiple steps of angiogenesis in syngeneic murine pleural mesothelioma The Annals of Thoracic Surgery. 78: 1042-1051. PMID 15337045 DOI: 10.1016/J.Athoracsur.2004.03.021 |
0.31 |
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| 2004 |
Wu JC, Chen IY, Wang Y, Tseng JR, Chhabra A, Salek M, Min JJ, Fishbein MC, Crystal R, Gambhir SS. Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium. Circulation. 110: 685-91. PMID 15302807 DOI: 10.1161/01.Cir.0000138153.02213.22 |
0.326 |
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| 2004 |
Vincent T, Pettersson RF, Crystal RG, Leopold PL. Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells. Journal of Virology. 78: 8047-8058. PMID 15254176 DOI: 10.1128/Jvi.78.15.8047-8058.2004 |
0.356 |
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| 2004 |
Worgall S, Busch A, Rivara M, Bonnyay D, Leopold PL, Merritt R, Hackett NR, Rovelink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG. Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses. Journal of Virology. 78: 2572-80. PMID 14963160 DOI: 10.1128/Jvi.78.5.2572-2580.2004 |
0.306 |
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| 2004 |
Whitlock PR, Hackett NR, Leopold PL, Rosengart TK, Crystal RG. Adenovirus-Mediated Transfer of a Minigene Expressing Multiple Isoforms of VEGF Is More Effective at Inducing Angiogenesis Than Comparable Vectors Expressing Individual VEGF cDNAs Molecular Therapy. 9: 67-75. PMID 14741779 DOI: 10.1016/J.Ymthe.2003.09.014 |
0.319 |
|
| 2004 |
Cheng J, Zhang F, Lam G, Hackett NR, Wang S, Amano H, Shmelkov SV, Young LM, Hempstead B, Crystal RG, Rafii S. Adenovirus Vector E4 Gene Promotes Angiogenesis through Modulation of Junctional Connexin 40 and 43 Expression. Blood. 104: 5277-5277. DOI: 10.1182/Blood.V104.11.5277.5277 |
0.314 |
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| 2004 |
Zhu W, Boachie-Adjei O, Rawlins B, Crystal RG, Hidaka C. 888. A BMP2/7 Fusion Gene Enhances Osteoblastic Differentiation in Mesenchymal Cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.794 |
0.327 |
|
| 2004 |
Tahara M, Pergolizzi RG, Crystal RG. 711. Trans-splicing correction of CD40 ligand deficiency resulting in naturally regulated correction of a murine model of hyper IgM X-linked immunodeficiency Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.727 |
0.339 |
|
| 2004 |
Nakayama K, Pergolizzi RG, Crystal RG. 670. Intracellular Shigatoxin 1A1 Delivered by Adenovirus-Mediated Segmental Trans-Splicing Causes Apototic Cell Death In Vitro and In Vivo Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.634 |
0.35 |
|
| 2004 |
Worgall S, Rivara M, Krause A, Hackett NR, Rovelink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG. 689. Protection against pulmonary infection with P. aeruginosa following immunization with an adenovirus vector expressing a P. aeruginosa OprF Epitope Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.589 |
0.309 |
|
| 2004 |
Boyer J, Krause A, Qiu J, Hackett N, Kobinger G, Zhi Y, Wilson JM, Crystal RG. 558. Anti-SARS Humoral and Cellular Immunity Evoked by an Adenovirus Vector Expressing Spike Glycoprotein from SARS Coronavirus Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.485 |
0.325 |
|
| 2004 |
Tertilt C, Worgall S, Rivara MC, Crystal RG. 557. Co-administration of an adenovirus encoding the B cell stimulating factor BAFF with heat-inactivated Pseudomonas aeruginosa leads to increased anti-pseudomonal humoral immunity Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.484 |
0.307 |
|
| 2004 |
Kaner RJ, Santiago F, Igonkin D, Schaack J, Amalfitano A, Crystal RG. 543. Ad DNA polymerase and preterminal protein (pTP) genes each mediate inhibition of HIV-1 replication in human alveolar macrophages Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.458 |
0.301 |
|
| 2004 |
Hackett NR, Redmond DE, Sondhi D, Giannaris EL, Vassallo E, Kaminsky SM, Crystal RG. 432. Safety of Administration of AAV2CUhCLN2, a Candidate Treatment for Late Infantile Neuronal Lipofuscinosis to the Brain of Rats and Non-Human Primates Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.395 |
0.305 |
|
| 2004 |
Kasuya K, Boyer JL, Tan Y, Alipui DO, Hackett NR, Crystal RG. 372. Passive Immunotherapy for Anthrax Mediated by an Adenovirus Expressing Anti-Protective Antigen Single Chain Antibody Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.315 |
0.31 |
|
| 2004 |
De BP, Wasif N, Hackett NR, Gao G, Wilson JM, Crystal RG. 338. Therapeutic Levels for |[alpha]|1-Antitrypsin Following Intrapleural Administration of a Non-Human Primate Serotype rh10 AAV Vector Expressing |[alpha]|1-Antitrypsin Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.280 |
0.36 |
|
| 2004 |
Pergolizzi RG, Dragos R, Nakayama K, Wagner D, Crystal RG. 160. Overcoming the size limitations of gene transfer vectors: using segmental trans-splicing to deliver the coding sequence of Von Willebrand factor Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.120 |
0.348 |
|
| 2004 |
Saitoh H, Heguy A, O'Connor TP, Harvey B, Leopold PL, Hackett NR, Cieciuch A, Crystal RG. 488. Adenovirus-mediated delivery of ADAM10, a novel candidate gene for COPD, results in emphysematous changes in the mouse lung Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.1017 |
0.403 |
|
| 2004 |
Sondhi D, Peterson DA, Giannaris EL, Vassallo E, Hackett NR, Sanders CT, Bjugstad KB, Sladek JRR, Crystal RG. 1060. Long Term Expression of TPP-I in Rat and Non-Human Primate Brain Following Administration of AAV2CUhCLN2, a Candidate Gene Therapy Treatment for Late Infantile Neuronal Ceroid Lipofuscinosis Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.1005 |
0.331 |
|
| 2003 |
Heguy A, Harvey BG, O'Connor TP, Hackett NR, Crystal RG. Sampling-dependent up-regulation of gene expression in sequential samples of human airway epithelial cells. Molecular Medicine (Cambridge, Mass.). 9: 200-8. PMID 15208741 DOI: 10.2119/2003-00051.Crystal |
0.326 |
|
| 2003 |
Merritt RE, Mahtabifard A, Yamada RE, Crystal RG, Korst RJ. Cisplatin augments cytotoxic T-lymphocyte-mediated antitumor immunity in poorly immunogenic murine lung cancer. The Journal of Thoracic and Cardiovascular Surgery. 126: 1609-1617. PMID 14666041 DOI: 10.1016/S0022-5223(03)00707-4 |
0.364 |
|
| 2003 |
Mahtabifard A, Merritt RE, Yamada RE, Crystal RG, Korst RJ. In vivo gene transfer of pigment epithelium-derived factor inhibits tumor growth in syngeneic murine models of thoracic malignancies. The Journal of Thoracic and Cardiovascular Surgery. 126: 28-38. PMID 12878936 DOI: 10.1016/S0022-5223(02)73616-7 |
0.356 |
|
| 2003 |
Zhang F, Hackett NR, Lam G, Cheng J, Pergolizzi R, Luo L, Shmelkov SV, Edelberg J, Crystal RG, Rafii S. Green fluorescent protein selectively induces HSP70-mediated up-regulation of COX-2 expression in endothelial cells. Blood. 102: 2115-21. PMID 12805066 DOI: 10.1182/Blood-2003-01-0049 |
0.309 |
|
| 2003 |
Hackett NR, Heguy A, Harvey BG, O'Connor TP, Luettich K, Flieder DB, Kaplan R, Crystal RG. Variability of antioxidant-related gene expression in the airway epithelium of cigarette smokers. American Journal of Respiratory Cell and Molecular Biology. 29: 331-43. PMID 12702543 DOI: 10.1165/Rcmb.2002-0321Oc |
0.333 |
|
| 2003 |
O'Bryan L, Pinkston P, Kumaraswami V, Vijayan V, Yenokida G, Rosenberg HF, Crystal R, Ottesen EA, Nutman TB. Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia. Infection and Immunity. 71: 1337-42. PMID 12595450 DOI: 10.1128/Iai.71.3.1337-1342.2003 |
0.319 |
|
| 2002 |
Worgall S, Martushova K, Busch A, Lande L, Crystal RG. Apoptosis induced by Pseudomonas aeruginosa in antigen presenting cells is diminished by genetic modification with CD40 ligand. Pediatric Research. 52: 636-44. PMID 12409507 DOI: 10.1203/00006450-200211000-00006 |
0.343 |
|
| 2002 |
Harvey B, McKinney RL, Rosengart T, Lesser ML, Crystal RG. Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes. Molecular Therapy. 6: 287-297. PMID 12349828 DOI: 10.1006/Mthe.2002.0658 |
0.318 |
|
| 2002 |
Mae M, Crystal RG. Gene transfer to the pleural mesothelium as a strategy to deliver proteins to the lung parenchyma. Human Gene Therapy. 13: 1471-1482. PMID 12215268 DOI: 10.1089/10430340260185102 |
0.39 |
|
| 2002 |
Bergstein I, Leopold PL, Sato N, Panteleyev A, Christiano A, Crystal R. In vivo enhanced expression of patched dampens the sonic hedgehog pathway. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 258-64. PMID 12161193 DOI: 10.1006/Mthe.2002.0628 |
0.307 |
|
| 2002 |
Crystal RG, Bitterman PB, Mossman B, Schwarz MI, Sheppard D, Almasy L, Chapman HA, Friedman SL, King TE, Leinwand LA, Liotta L, Martin GR, Schwartz DA, Schultz GS, Wagner CR, et al. Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. American Journal of Respiratory and Critical Care Medicine. 166: 236-46. PMID 12119236 DOI: 10.1164/Rccm.2201069 |
0.305 |
|
| 2002 |
Hidaka C, Ibarra C, Hannafin JA, Torzilli PA, Quitoriano M, Jen SS, Warren RF, Crystal RG. Formation of vascularized meniscal tissue by combining gene therapy with tissue engineering. Tissue Engineering. 8: 93-105. PMID 11886658 DOI: 10.1089/107632702753503090 |
0.305 |
|
| 2002 |
Korst RJ, Mahtabifard A, Yamada R, Crystal RG. Effect of adenovirus gene transfer vectors on the immunologic functions of mouse dendritic cells. Molecular Therapy. 5: 307-315. PMID 11863421 DOI: 10.1006/Mthe.2002.0538 |
0.348 |
|
| 2002 |
Crystal RG, Harvey BG, Wisnivesky JP, O'Donoghue KA, Chu KW, Maroni J, Muscat JC, Pippo AL, Wright CE, Kaner RJ, Leopold PL, Kessler PD, Rasmussen HS, Rosengart TK, Hollmann C. Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions. Human Gene Therapy. 13: 65-100. PMID 11779413 DOI: 10.1089/10430340152712647 |
0.306 |
|
| 2002 |
Harvey BG, Maroni J, O'Donoghue KA, Chu KW, Muscat JC, Pippo AL, Wright CE, Hollmann C, Wisnivesky JP, Kessler PD, Rasmussen HS, Rosengart TK, Crystal RG. Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions. Human Gene Therapy. 13: 15-63. PMID 11779412 DOI: 10.1089/10430340152712638 |
0.34 |
|
| 2001 |
Song W, Crystal RG. Adenoviral-Vector-Mediated Gene Transfer to Dendritic Cells Methods in Molecular Medicine. 64: 429-439. PMID 21374280 DOI: 10.1385/1-59259-150-7:429 |
0.311 |
|
| 2001 |
Landesberg LJ, Ramalingam R, Lee K, Rosengart TK, Crystal RG. Upregulation of transcription factors in lung in the early phase of postpneumonectomy lung growth. American Journal of Physiology-Lung Cellular and Molecular Physiology. 281. PMID 11597905 DOI: 10.1152/Ajplung.2001.281.5.L1138 |
0.316 |
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| 2001 |
Seidman MA, Hogan SM, Wendland RL, Worgall S, Crystal RG, Leopold PL. Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 13-21. PMID 11472101 DOI: 10.1006/Mthe.2001.0414 |
0.321 |
|
| 2001 |
Walters RW, van't Hof W, Yi SM, Schroth MK, Zabner J, Crystal RG, Welsh MJ. Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia. Journal of Virology. 75: 7703-11. PMID 11462042 DOI: 10.1128/Jvi.75.16.7703-7711.2001 |
0.333 |
|
| 2001 |
Moore MA, Hattori K, Heissig B, Shieh JH, Dias S, Crystal RG, Rafii S. Mobilization of endothelial and hematopoietic stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF, and angiopoietin-1. Annals of the New York Academy of Sciences. 938: 36-45; discussion 45. PMID 11458524 DOI: 10.1111/J.1749-6632.2001.Tb03572.X |
0.318 |
|
| 2001 |
Worgall S, Kikuchi T, Singh R, Martushova K, Lande L, Crystal RG. Protection against pulmonary infection with Pseudomonas aeruginosa following immunization with P. aeruginosa-pulsed dendritic cells. Infection and Immunity. 69: 4521-7. PMID 11401995 DOI: 10.1128/Iai.69.7.4521-4527.2001 |
0.485 |
|
| 2001 |
Harvey B, Hackett NR, Ely S, Crystal RG. Host responses and persistence of vector genome following intrabronchial administration of an E1(-)E3(-) adenovirus gene transfer vector to normal individuals. Molecular Therapy. 3: 206-215. PMID 11237677 DOI: 10.1006/Mthe.2000.0244 |
0.374 |
|
| 2001 |
Hof Wv, Crystal RG. Manipulation of the cytoplasmic and transmembrane domains alters cell surface levels of the coxsackie-adenovirus receptor and changes the efficiency of adenovirus infection. Human Gene Therapy. 12: 25-34. PMID 11177539 DOI: 10.1089/104303401450933 |
0.304 |
|
| 2001 |
Crystal RG. Research opportunities and advances in lung disease. Jama. 285: 612-618. PMID 11176868 DOI: 10.1001/Jama.285.5.612 |
0.364 |
|
| 2001 |
Sanborn TA, Hackett NR, Lee LY, El-Sawy T, Blanco I, Tarazona N, Deutsch E, Crystal R, Rosengart TK. Percutaneous endocardial transfer and expression of genes to the myocardium utilizing fluoroscopic guidance. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. 52: 260-6. PMID 11170342 DOI: 10.1002/1522-726X(200102)52:2<260::Aid-Ccd1061>3.0.Co;2-T |
0.334 |
|
| 2001 |
Kaner RJ, Crystal RG. Compartmentalization of vascular endothelial growth factor to the epithelial surface of the human lung. Molecular Medicine. 7: 240-246. DOI: 10.1007/Bf03401843 |
0.339 |
|
| 2000 |
Hackett NR, Sawy TE, Lee LY, Silva I, O'Leary J, Rosengart TK, Crystal RG. Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo. Molecular Therapy. 2: 649-656. PMID 11124067 DOI: 10.1006/Mthe.2000.0203 |
0.355 |
|
| 2000 |
Ramalingam R, Worgall S, Rafii S, Crystal RG. Downregulation of CXCR4 gene expression in primary human endothelial cells following infection with E1(-)E4(+) adenovirus gene transfer vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 381-6. PMID 11020354 DOI: 10.1006/Mthe.2000.0131 |
0.309 |
|
| 2000 |
Kikuchi T, Worgall S, Singh R, Moore MA, Crystal RG. Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4+ T cells. Nature Medicine. 6: 1154-9. PMID 11017148 DOI: 10.1038/80498 |
0.472 |
|
| 2000 |
Worgall S, Worgall TS, Kostarelos K, Singh R, Leopold PL, Hackett NR, Crystal RG. Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 39-48. PMID 10933910 DOI: 10.1006/Mthe.1999.0013 |
0.627 |
|
| 2000 |
Kaner RJ, Ladetto JV, Singh R, Fukuda N, Matthay MA, Crystal RG. Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. American Journal of Respiratory Cell and Molecular Biology. 22: 657-64. PMID 10837361 DOI: 10.1165/Ajrcmb.22.6.3779 |
0.529 |
|
| 2000 |
Labow D, Lee S, Ginsberg RJ, Crystal RG, Korst RJ. Adenovirus vector-mediated gene transfer to regional lymph nodes. Human Gene Therapy. 11: 759-69. PMID 10757355 DOI: 10.1089/10430340050015653 |
0.336 |
|
| 2000 |
Cipolla DC, Gonda I, Shak S, Kovesdi I, Crystal R, Sweeney TD. Coarse spray delivery to a localized region of the pulmonary airways for gene therapy. Human Gene Therapy. 11: 361-71. PMID 10680848 DOI: 10.1089/10430340050016085 |
0.342 |
|
| 2000 |
Lee LY, Patel SR, Hackett NR, Mack CA, Polce DR, El-Sawy T, Hachamovitch R, Zanzonico P, Sanborn TA, Parikh M, Isom OW, Crystal RG, Rosengart TK. Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121. The Annals of Thoracic Surgery. 69: 14-23; discussion 23. PMID 10654479 DOI: 10.1016/S0003-4975(99)01102-9 |
0.301 |
|
| 2000 |
MacKenzie KL, Hackett NR, Crystal RG, Moore MAS. Adenoviral vector-mediated gene transfer to primitive human hematopoietic progenitor cells: assessment of transduction and toxicity in long-term culture. Blood. 96: 100-108. DOI: 10.1182/Blood.V96.1.100.013K41_100_108 |
0.357 |
|
| 2000 |
Schulick AH, Heller J, Kent KC, Crystal RG. Adenovirus-mediated gene transfer into hypoxic cells Journal of the American College of Surgeons. 191. DOI: 10.1016/S1072-7515(00)00379-3 |
0.321 |
|
| 1999 |
Hirschowitz EA, Naama HA, Evoy D, Lieberman MD, Daly J, Crystal RG. Regional treatment of hepatic micrometastasis by adenovirus vector-mediated delivery of interleukin-2 and interleukin-12 cDNAs to the hepatic parenchyma. Cancer Gene Therapy. 6: 491-8. PMID 10608345 DOI: 10.1038/Sj.Cgt.7700089 |
0.311 |
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| 1999 |
Ozawa H, Ding W, Torii H, Hosoi J, Seiffert K, Campton K, Granstein RD, Hackett NR, Topf N, Crystal RG. Granulocyte-macrophage colony-stimulating factor gene transfer to dendritic cells or epidermal cells augments their antigen-presenting function including induction of anti-tumor immunity. Journal of Investigative Dermatology. 113: 999-1005. PMID 10594743 DOI: 10.1046/J.1523-1747.1999.00769.X |
0.314 |
|
| 1999 |
Crystal RG. Bad for cats, good for humans? Modified feline immunodeficiency virus for gene therapy. Journal of Clinical Investigation. 104: 1491-1493. PMID 10587510 DOI: 10.1172/Jci8838 |
0.335 |
|
| 1999 |
Harvey BG, Worgall S, Ely S, Leopold PL, Crystal RG. Cellular immune responses of healthy individuals to intradermal administration of an E1-E3- adenovirus gene transfer vector. Human Gene Therapy. 10: 2823-37. PMID 10584928 DOI: 10.1089/10430349950016555 |
0.321 |
|
| 1999 |
Ramalingam R, Rafii S, Worgall S, Hackett NR, Crystal RG. Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector. Journal of Virology. 73: 10183-90. PMID 10559334 DOI: 10.1128/Jvi.73.12.10183-10190.1999 |
0.373 |
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| 1999 |
Harvey B, Leopold PL, Hackett NR, Grasso TM, Williams PM, Tucker AL, Kaner RJ, Ferris B, Gonda I, Sweeney TD, Ramalingam R, Kovesdi I, Shak S, Crystal RG. Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus Journal of Clinical Investigation. 104: 1245-1255. PMID 10545523 DOI: 10.1172/Jci7935 |
0.359 |
|
| 1999 |
Rosengart TK, Lee LY, Patel SR, Kligfield PD, Okin PM, Hackett NR, Isom OW, Crystal RG. Six-month assessment of a phase I trial of angiogenic gene therapy for the treatment of coronary artery disease using direct intramyocardial administration of an adenovirus vector expressing the VEGF121 cDNA. Annals of Surgery. 230: 466-70; discussion 4. PMID 10522716 DOI: 10.1097/00000658-199910000-00002 |
0.308 |
|
| 1999 |
Worgall S, Bezdicek P, Kim MK, Park JG, Singh R, Christofidou-Solomidou M, Prince A, Kovesdi I, Schreiber AD, Crystal RG. Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium. The Journal of Clinical Investigation. 104: 409-18. PMID 10449433 DOI: 10.1172/Jci5432 |
0.555 |
|
| 1999 |
Rosengart TK, Lee LY, Patel SR, Sanborn TA, Parikh M, Bergman GW, Hachamovitch R, Szulc M, Kligfield PD, Okin PM, Hahn RT, Devereux RB, Post MR, Hackett NR, Foster T, ... ... Crystal RG, et al. Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation. 100: 468-74. PMID 10430759 DOI: 10.1161/01.Cir.100.5.468 |
0.314 |
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| 1999 |
Roum JH, Borok Z, McElvaney NG, Grimes GJ, Bokser AD, Buhl R, Crystal RG. Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis. Journal of Applied Physiology. 87: 438-443. PMID 10409605 DOI: 10.1152/Jappl.1999.87.1.438 |
0.313 |
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| 1999 |
Harvey BG, Hackett NR, El-Sawy T, Rosengart TK, Hirschowitz EA, Lieberman MD, Lesser ML, Crystal RG. Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs. Journal of Virology. 73: 6729-42. PMID 10400771 DOI: 10.1128/Jvi.73.8.6729-6742.1999 |
0.31 |
|
| 1999 |
Lee LY, Zhou X, Polce DR, El-Sawy T, Patel SR, Thakker GD, Narumi K, Crystal RG, Rosengart TK. Exogenous control of cardiac gene therapy: evidence of regulated myocardial transgene expression after adenovirus and adeno-associated virus transfer of expression cassettes containing corticosteroid response element promoters. The Journal of Thoracic and Cardiovascular Surgery. 118: 26-4, discussion 34-. PMID 10384181 DOI: 10.1016/S0022-5223(99)70137-6 |
0.322 |
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| 1999 |
Patel SR, Lee LY, Mack CA, Polce DR, El-Sawy T, Hackett NR, Ilercil A, Jones EC, Hahn RT, Isom OW, Rosengart TK, Crystal RG. Safety of direct myocardial administration of an adenovirus vector encoding vascular endothelial growth factor 121. Human Gene Therapy. 10: 1331-48. PMID 10365664 DOI: 10.1089/10430349950018012 |
0.315 |
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| 1999 |
Worgall S, Connor R, Kaner RJ, Fenamore E, Sheridan K, Singh R, Crystal RG. Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages. Journal of Virology. 73: 5865-74. PMID 10364338 DOI: 10.1128/Jvi.73.7.5865-5874.1999 |
0.463 |
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| 1999 |
Crystal RG. In vivo and ex vivo gene therapy strategies to treat tumors using adenovirus gene transfer vectors. Cancer Chemotherapy and Pharmacology. 43. PMID 10357566 DOI: 10.1007/S002800051105 |
0.313 |
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| 1999 |
Peng Y, Trevejo J, Zhou J, Marino MW, Crystal RG, Falck-Pedersen E, Elkon KB. Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung Journal of Virology. 73: 5098-5109. PMID 10233973 DOI: 10.1128/Jvi.73.6.5098-5109.1999 |
0.341 |
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| 1999 |
Hirschowitz EA, Crystal RG. Adenovirus-mediated expression of interleukin-12 induces natural killer cell activity and complements adenovirus-directed gp75 treatment of melanoma lung metastases. American Journal of Respiratory Cell and Molecular Biology. 20: 935-941. PMID 10226063 DOI: 10.1165/Ajrcmb.20.5.3412 |
0.357 |
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| 1999 |
Chung I, Schwartz PE, Crystal RG, Pizzorno G, Leavitt J, Deisseroth AB. Use of L-plastin promoter to develop an adenoviral system that confers transgene expression in ovarian cancer cells but not in normal mesothelial cells. Cancer Gene Therapy. 6: 99-106. PMID 10195877 DOI: 10.1038/Sj.Cgt.7700017 |
0.333 |
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| 1999 |
Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J, Finberg R, Falck-Pedersen E, Crystal RG. Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. American Journal of Respiratory Cell and Molecular Biology. 20: 361-70. PMID 10030833 DOI: 10.1165/Ajrcmb.20.3.3398 |
0.538 |
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| 1999 |
Hidaka C, Milano E, Leopold PL, Bergelson JM, Hackett NR, Finberg RW, Wickham TJ, Kovesdi I, Roelvink P, Crystal RG. CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts Journal of Clinical Investigation. 103: 579-587. PMID 10021467 DOI: 10.1172/Jci5309 |
0.318 |
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| 1999 |
Bezdicek P, Worgall S, Kovesdi I, Kim M, Park J, Vincent T, Leopold PL, Schreiber AD, Crystal RG. Enhanced Liver Uptake of Opsonized Red Blood Cells After In Vivo Transfer of FcγRIIA cDNA to the Liver Blood. 94: 3448-3455. DOI: 10.1182/Blood.V94.10.3448.422K02_3448_3455 |
0.348 |
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| 1999 |
Ramalingam R, Rafii S, Worgall S, Brough DE, Crystal RG. E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells. Blood. 93: 2936-2944. DOI: 10.1182/Blood.V93.9.2936.409A14_2936_2944 |
0.331 |
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| 1999 |
Worgall S, Singh R, Leopold PL, Kaner RJ, Hackett NR, Topf N, Moore MA, Crystal RG. Selective Expansion of Alveolar Macrophages In Vivo by Adenovirus-Mediated Transfer of the Murine Granulocyte-Macrophage Colony-Stimulating Factor cDNA Blood. 93: 655-666. DOI: 10.1182/Blood.V93.2.655.402K02_655_666 |
0.544 |
|
| 1998 |
Ko N, Kojima A, Crystal RG. Adenovirus vector-mediated perforin expression driven by a glucocorticoid-inducible promoter inhibits tumor growth in vivo American Journal of Respiratory Cell and Molecular Biology. 19: 936-941. PMID 9843928 DOI: 10.1165/Ajrcmb.19.6.3289 |
0.317 |
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| 1998 |
Hirschowitz E, Leonard S, Song W, Ferris B, Leopold P, Lewis J, Bowne W, Wang S, Houghton A, Crystal R. Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma Gene Therapy. 5: 975-983. PMID 9813669 DOI: 10.1038/Sj.Gt.3300668 |
0.312 |
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| 1998 |
Gall JG, Crystal RG, Falck-Pedersen E. Construction and characterization of hexon-chimeric adenoviruses: specification of adenovirus serotype. Journal of Virology. 72: 10260-4. PMID 9811772 DOI: 10.1128/Jvi.72.12.10260-10264.1998 |
0.317 |
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| 1998 |
Danel C, Erzurum SC, Prayssac P, Tony Eissa N, Crystal RG, Hervé P, Baudet B, Mazmanian M, Lemarchand P. Gene therapy for oxidant injury-related diseases: Adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury Human Gene Therapy. 9: 1487-1496. PMID 9681420 DOI: 10.1089/Hum.1998.9.10-1487 |
0.336 |
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| 1998 |
Suzuki M, Singh R, Moore MAS, Song W, Crystal RG. Similarity of strain- and route-dependent murine responses to an adenovirus vector using the homologous thrombopoietin cDNA as the reporter genes. Human Gene Therapy. 9: 1223-1231. PMID 9625262 DOI: 10.1089/Hum.1998.9.8-1223 |
0.507 |
|
| 1998 |
Topf N, Worgall S, Hackett NR, Crystal RG. Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma. Gene Therapy. 5: 507-13. PMID 9614575 DOI: 10.1038/Sj.Gt.3300611 |
0.311 |
|
| 1998 |
Mason RJ, Crystal RG. Pulmonary Cell Biology American Journal of Respiratory and Critical Care Medicine. 157. PMID 9563764 DOI: 10.1164/Ajrccm.157.4.Nhlbi-3 |
0.313 |
|
| 1998 |
Kojima A, Hackett NR, Ohwada A, Crystal RG. In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors. Journal of Clinical Investigation. 101: 1789-1796. PMID 9541511 DOI: 10.1172/Jci119888 |
0.352 |
|
| 1998 |
Stern M, Caplen NJ, Browning JE, Griesenbach U, Sorgi F, Huang L, Gruenert DC, Marriot C, Crystal RG, Geddes DM, Alton EW. The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro. Gene Therapy. 5: 91-8. PMID 9536269 DOI: 10.1038/Sj.Gt.3300556 |
0.352 |
|
| 1998 |
Leopold PL, Ferris B, Grinberg I, Worgall S, Hackett NR, Crystal RG. Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Human Gene Therapy. 9: 367-78. PMID 9508054 DOI: 10.1089/Hum.1998.9.3-367 |
0.339 |
|
| 1998 |
Suzuki M, Singh RN, Crystal RG. Pharmacological expression in rat hepatocytes of a gene transferred by an adenovirus vector enabled by a chimeric promoter containing multiple cyclic adenosine monophosphate response elements Hepatology. 27: 160-165. PMID 9425932 DOI: 10.1002/Hep.510270125 |
0.333 |
|
| 1998 |
Narumi K, Suzuki M, Song W, Moore MA, Crystal RG. Intermittent, Repetitive Corticosteroid-Induced Upregulation of Platelet Levels After Adenovirus-Mediated Transfer to the Liver of a Chimeric Glucocorticoid-Responsive Promoter Controlling the Thrombopoietin cDNA Blood. 92: 822-833. DOI: 10.1182/Blood.V92.3.822 |
0.353 |
|
| 1998 |
Garcia-Sanchez F, Pizzorno G, Fu S, Nanakorn T, Krause D, Liang J, Adams E, Leffert J, Yin L, Cooperberg M, Hanania E, Wang W, Won J, Peng X, Cote R, ... ... Crystal R, et al. Cytosine Deaminase Adenoviral Vector and 5-Fluorocytosine Selectively Reduce Breast Cancer Cells 1 Million-Fold When They Contaminate Hematopoietic Cells: A Potential Purging Method for Autologous Transplantation Blood. 92: 672-682. DOI: 10.1182/Blood.V92.2.672 |
0.309 |
|
| 1998 |
Frey BM, Hackett NR, Bergelson JM, Finberg R, Crystal RG, Moore MAS, Rafii S. High-efficiency gene transfer into ex vivo expanded human hematopoietic progenitors and precursor cells by adenovirus vectors. Blood. 91: 2781-2792. DOI: 10.1182/Blood.V91.8.2781.2781_2781_2792 |
0.326 |
|
| 1997 |
Suzuki M, Singh R, Crystal R. Ability of a chimeric cAMP-responsive promoter to confer pharmacologic control of CFTR cDNA expression and cAMP-mediated Cl- secretion. Gene Therapy. 4: 1195-1201. PMID 9425443 DOI: 10.1038/Sj.Gt.3300512 |
0.467 |
|
| 1997 |
Abrahamsen K, Kong HL, Mastrangeli A, Brough D, Lizonova A, Crystal RG, Falck-Pedersen E. Construction of an adenovirus type 7a E1A- vector Journal of Virology. 71: 8946-8951. PMID 9343264 DOI: 10.1128/Jvi.71.11.8946-8951.1997 |
0.327 |
|
| 1997 |
Pili R, Chang J, Muhlhauser J, Crystal RG, Capogrossi MC, Passaniti A. Adenovirus-mediated gene transfer of fibroblast growth factor-1: Angiogenesis and tumorigenicity in nude mice International Journal of Cancer. 73: 258-263. PMID 9335452 DOI: 10.1002/(Sici)1097-0215(19971009)73:2<258::Aid-Ijc16>3.0.Co;2-B |
0.339 |
|
| 1997 |
Worgall S, Leopold PL, Wolff G, Ferris B, Van Roijen N, Crystal RG. Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract. Human Gene Therapy. 8: 1675-84. PMID 9322870 DOI: 10.1089/Hum.1997.8.14-1675 |
0.331 |
|
| 1997 |
Elkon KB, Liu CC, Gall JG, Trevejo J, Marino MW, Abrahamsen KA, Song X, Zhou JL, Old LJ, Crystal RG, Falck-Pedersen E. Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 94: 9814-9. PMID 9275208 DOI: 10.1073/Pnas.94.18.9814 |
0.313 |
|
| 1997 |
Song W, Kong HL, Traktman P, Crystal RG. Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors. Human Gene Therapy. 8: 1207-17. PMID 9215738 DOI: 10.1089/Hum.1997.8.10-1207 |
0.34 |
|
| 1997 |
Cannizzo SJ, Frey BM, Raffi S, Moore MA, Eaton D, Suzuki M, Singh R, Mack CA, Crystal RG. Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA. Nature Biotechnology. 15: 570-3. PMID 9181581 DOI: 10.1038/Nbt0697-570 |
0.5 |
|
| 1997 |
Mack CA, Song WR, Carpenter H, Wickham TJ, Kovesdi I, Harvey BG, Magovern CJ, Isom OW, Rosengart T, Falck-Pedersen E, Hackett NR, Crystal RG, Mastrangeli A. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype Human Gene Therapy. 8: 99-109. PMID 8989999 DOI: 10.1089/Hum.1997.8.1-99 |
0.332 |
|
| 1997 |
Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Human Gene Therapy. 8: 37-44. PMID 8989993 DOI: 10.1089/Hum.1997.8.1-37 |
0.328 |
|
| 1997 |
Wolff G, Worgall S, van Rooijen N, Song WR, Harvey BG, Crystal RG. Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. Journal of Virology. 71: 624-9. PMID 8985392 DOI: 10.1128/Jvi.71.1.624-629.1997 |
0.355 |
|
| 1996 |
Dong Y, Wen P, Manome Y, Parr M, Hirshowitz A, Chen L, Hirschowitz EA, Crystal R, Weichselbaum R, Kufe DW, Fine HA. In Vivo Replication-Deficient Adenovirus Vector-Mediated Transduction of the Cytosine Deaminase Gene Sensitizes Glioma Cells to 5-Fluorocytosine Human Gene Therapy. 7: 713-720. PMID 8919593 DOI: 10.1089/Hum.1996.7.6-713 |
0.33 |
|
| 1996 |
Suzuki M, Singh RN, Crystal RG. Regulatable promoters for use in gene therapy applications: modification of the 5'-flanking region of the CFTR gene with multiple cAMP response elements to support basal, low-level gene expression that can be upregulated by exogenous agents that raise intracellular levels of cAMP. Human Gene Therapy. 7: 1883-1893. PMID 8894680 DOI: 10.1089/Hum.1996.7.15-1883 |
0.337 |
|
| 1996 |
Silver RF, Crystal RG, Moller DR. Limited heterogeneity of biased T-cell receptor Vβ gene usage in lung but not blood T cells in active pulmonary sarcoidosis Immunology. 88: 516-523. PMID 8881751 DOI: 10.1046/J.1365-2567.1996.D01-683.X |
0.316 |
|
| 1996 |
Mastrangeli A, Harvey BG, Yao J, Wolff G, Kovesdi I, Crystal RG, Falck-Pedersen E. "Sero-switch" adenovirus-mediated in vivo gene transfer: Circumvention of anti-Adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype Human Gene Therapy. 7: 79-87. PMID 8825871 DOI: 10.1089/Hum.1996.7.1-79 |
0.35 |
|
| 1996 |
Feuerbach FJ, Crystal RG. Progress in human gene therapy Kidney International. 49: 1791-1794. PMID 8743499 DOI: 10.1038/Ki.1996.269 |
0.33 |
|
| 1996 |
Wersto RP, Rosenthal ER, Crystal RG, Spring KR. Uptake of fluorescent dyes associated with the functional expression of the cystic fibrosis transmembrane conductance regulator in epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 1167-72. PMID 8577734 DOI: 10.1073/Pnas.93.3.1167 |
0.326 |
|
| 1995 |
Hay JG, McElvaney NG, Herena J, Crystal RG. Modification of Nasal Epithelial Potential Differences of Individuals with Cystic Fibrosis Consequent to Local Administration of a Normal CFTR cDNA Adenovirus Gene Transfer Vector Human Gene Therapy. 6: 1487-1496. PMID 8573621 DOI: 10.1089/Hum.1995.6.11-1487 |
0.318 |
|
| 1995 |
Mühlhauser J, Pili R, Merrill MJ, Maeda H, Passaniti A, Crystal RG, Capogrossi MC. In vivo angiogenesis induced by recombinant adenovirus vectors coding either for secreted or nonsecreted forms of acidic fibroblast growth factor. Human Gene Therapy. 6: 1457-65. PMID 8573618 DOI: 10.1089/Hum.1995.6.11-1457 |
0.32 |
|
| 1995 |
Miyashita A, Crystal RG, Hay JG. Identification of a 27 bp 5′-flanking region element responsible for the low level constitutive expression of the human cytosolic phospholipase A2 gene Nucleic Acids Research. 23: 293-301. PMID 7862535 DOI: 10.1093/Nar/23.2.293 |
0.326 |
|
| 1995 |
Korst RJ, Bewig B, Crystal RG. In vitro and in vivo transfer and expression of human surfactant SP-A- and SP-B-associated protein cDNAs mediated by replication-deficient, recombinant adenoviral vectors. Human Gene Therapy. 6: 277-287. PMID 7779911 DOI: 10.1089/Hum.1995.6.3-277 |
0.311 |
|
| 1995 |
Hay JG, Danel C, Chu CS, Crystal RG. Human CC10 gene expression in airway epithelium and subchromosomal locus suggest linkage to airway disease American Journal of Physiology - Lung Cellular and Molecular Physiology. 268. PMID 7733299 DOI: 10.1152/Ajplung.1995.268.4.L565 |
0.354 |
|
| 1995 |
Hirschowitz EA, Ohwada A, Pascal WR, Russi TJ, Crystal RG. In Vivo Adenovirus-Mediated Gene Transfer of the Escherichia coli Cytosine Deaminase Gene to Human Colon Carcinoma-Derived Tumors Induces Chemosensitivity to 5-Fluorocytosine Human Gene Therapy. 6: 1055-1063. PMID 7578418 DOI: 10.1089/Hum.1995.6.8-1055 |
0.323 |
|
| 1995 |
Crystal RG. Transfer of Genes to Humans: Early Lessons and Obstacles to Success Science. 270: 404-410. PMID 7569994 DOI: 10.1126/Science.270.5235.404 |
0.307 |
|
| 1995 |
Korst RJ, McElvaney NG, Chu C, Rosenfeld MA, Mastrangeli A, Hay J, Brody SL, Eissa NT, Danel C, Jaffe HA, Crystal RG. Gene therapy for the respiratory manifestations of cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 151. PMID 7533609 DOI: 10.1164/Ajrccm/151.3_Pt_2.S75 |
0.383 |
|
| 1994 |
Yoo JH, Erzurum SC, Hay JG, Lemarchand P, Crystal RG. Vulnerability of the human airway epithelium to hyperoxia: Constitutive expression of the catalase gene in human bronchial epithelial cells despite oxidant stress Journal of Clinical Investigation. 93: 297-302. PMID 8282800 DOI: 10.1172/Jci116959 |
0.362 |
|
| 1994 |
Maeda H, Danel C, Crystal RG. Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder Gastroenterology. 106: 1638-1644. PMID 8194711 DOI: 10.1016/0016-5085(94)90421-9 |
0.314 |
|
| 1994 |
Setoguchi Y, Jaffe HA, Danel C, Crystal RG. Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors Journal of Investigative Dermatology. 102: 415-421. PMID 8151119 DOI: 10.1111/1523-1747.Ep12372181 |
0.35 |
|
| 1994 |
Setoguchi Y, Jaffe HA, Chu CS, Crystal RG. Intraperitoneal in vivo gene therapy to deliver alpha 1-antitrypsin to the systemic circulation American Journal of Respiratory Cell and Molecular Biology. 10: 369-377. PMID 8136153 DOI: 10.1165/Ajrcmb.10.4.8136153 |
0.348 |
|
| 1994 |
Han SK, Brody SL, Crystal RG. Suppression of in vivo tumorigenicity of human lung cancer cells by retrovirus-mediated transfer of the human tumor necrosis factor-alpha cDNA. American Journal of Respiratory Cell and Molecular Biology. 11: 270-278. PMID 8086165 DOI: 10.1165/Ajrcmb.11.3.8086165 |
0.308 |
|
| 1994 |
Mastrangeli A, O'Connell B, Aladib W, Fox PC, Baum BJ, Crystal RG. Direct in vivo adenovirus-mediated gene transfer to salivary glands. American Journal of Physiology-Gastrointestinal and Liver Physiology. 266. PMID 8023944 DOI: 10.1152/Ajpgi.1994.266.6.G1146 |
0.308 |
|
| 1994 |
Yoshimura K, Chu CS, Crystal RG. Enhancer function of a 53-bp repetitive element in the 5' flanking region of the human neutrophil elastase gene Biochemical and Biophysical Research Communications. 204: 38-42. PMID 7945385 DOI: 10.1006/Bbrc.1994.2422 |
0.333 |
|
| 1994 |
Lemarchand P, Jones M, Danel C, Yamada I, Mastrangeli A, Crystal RG. In vivo adenovirus-mediated gene transfer to lungs via pulmonary artery Journal of Applied Physiology. 76: 2840-2845. PMID 7928919 DOI: 10.1152/Jappl.1994.76.6.2840 |
0.367 |
|
| 1994 |
Maruyama M, Hay JG, Yoshimura K, Chu CS, Crystal RG. Modulation of secretory leukoprotease inhibitor gene expression in human bronchial epithelial cells by phorbol ester. Journal of Clinical Investigation. 94: 368-375. PMID 7913712 DOI: 10.1172/Jci117331 |
0.363 |
|
| 1994 |
Birrer P, McElvaney NG, Rüdeberg A, Sommer CW, Liechti-Gallati S, Kraemer R, Hubbard R, Crystal RG. Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 150: 207-213. PMID 7912987 DOI: 10.1164/Ajrccm.150.1.7912987 |
0.325 |
|
| 1994 |
Eissa NT, Chu CS, Danel C, Crystal RG. Evaluation of the respiratory epithelium of normals and individuals with cystic fibrosis for the presence of adenovirus ela sequences relevant to the use of Ela- adenovirus vectors for gene therapy for the respiratory manifestations of cystic fibrosis Human Gene Therapy. 5: 1105-1114. PMID 7833370 DOI: 10.1089/Hum.1994.5.9-1105 |
0.348 |
|
| 1994 |
Rosenfeld MA, Rosenfeld SJ, Danel C, Banks TC, Crystal RG. Increasing Expression of the Normal Human CFTR cDNA in Cystic Fibrosis Epithelial Cells Results in a Progressive Increase in the Level of CFTR Protein Expression, but a Limit on the Level of cAMP-Stimulated Chloride Secretion Human Gene Therapy. 5: 1121-1129. PMID 7530494 DOI: 10.1089/Hum.1994.5.9-1121 |
0.349 |
|
| 1994 |
Crystal RG, Mcelvaney NG, Rosenfeld MA, Chu C, Mastrangeli A, Hay JG, Brody SL, Jaffe HA, Eissa NT, Danel C. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nature Genetics. 8: 42-51. PMID 7527271 DOI: 10.1038/Ng0994-42 |
0.336 |
|
| 1994 |
Brody SL, Metzger M, Danel C, Rosenfeld MA, Crystal RG. Acute responses of non-human primates to airway delivery of an adenovirus vector containing the human cystic fibrosis transmembrane conductance regulator cDNA. Human Gene Therapy. 5: 821-836. PMID 7526901 DOI: 10.1089/Hum.1994.5.7-821 |
0.382 |
|
| 1994 |
Brody SL, Jaffe HA, Han SK, Wersto RP, Crystal RG. Direct In Vivo Gene Transfer and Expression in Malignant Cells Using Adenovirus Vectors Human Gene Therapy. 5: 437-447. PMID 7519451 DOI: 10.1089/Hum.1994.5.4-437 |
0.353 |
|
| 1994 |
Brody SL, Crystal RG, Boris-Lawrie K, Ledley FD, Curiel DT. Adenovirus-mediated in vivo gene transfer Annals of the New York Academy of Sciences. 716: 90-103. PMID 7517653 DOI: 10.1111/J.1749-6632.1994.Tb21705.X |
0.395 |
|
| 1994 |
Rosenfeld MA, Chu C, Seth P, Danel C, Banks T, Yoneyama K, Yoshimura K, Crystal RG. Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA. Human Gene Therapy. 5: 331-342. PMID 7517189 DOI: 10.1089/Hum.1994.5.3-331 |
0.365 |
|
| 1994 |
Seth P, Rosenfeld M, Higginbotham J, Crystal RG. Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA. Journal of Virology. 68: 933-40. PMID 7507187 DOI: 10.1128/Jvi.68.2.933-940.1994 |
0.333 |
|
| 1994 |
Setoguchi Y, Danel C, Crystal RG. Stimulation of erythropoiesis by in vivo gene therapy: physiologic consequences of transfer of the human erythropoietin gene to experimental animals using an adenovirus vector Blood. 84: 2946-2953. DOI: 10.1182/Blood.V84.9.2946.Bloodjournal8492946 |
0.356 |
|
| 1993 |
Erzurum SC, Lemarchand P, Rosenfeld MA, Yoo JH, Crystal RG. Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA Nucleic Acids Research. 21: 1607-1612. PMID 8479912 DOI: 10.1093/Nar/21.7.1607 |
0.319 |
|
| 1993 |
Lemarchand P, Jones M, Yamada I, Crystal RG. In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circulation Research. 72: 1132-1138. PMID 8477524 DOI: 10.1161/01.Res.72.5.1132 |
0.342 |
|
| 1993 |
Mastrangeli A, Danel C, Rosenfeld MA, Stratford-Perricaudet L, Perricaudet M, Pavirani A, Lecocq JP, Crystal RG. Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. Journal of Clinical Investigation. 91: 225-234. PMID 8423221 DOI: 10.1172/Jci116175 |
0.371 |
|
| 1993 |
Gillissen A, Roum JH, Hoyt RF, Crystal RG. Aerosolization of superoxide dismutase: Augmentation of respiratory epithelial lining fluid antioxidant screen by aerosolization of recombinant human Cu++/Zn++ superoxide dismutase Chest. 104: 811-815. PMID 8396002 DOI: 10.1378/Chest.104.3.811 |
0.301 |
|
| 1993 |
Travis WD, Borok Z, Roum JH, Zhang J, Feuerstein I, Ferrans VJ, Crystal RG. Pulmonary Langerhans cell granulomatosis (histiocytosis X). A clinicopathologic study of 48 cases. The American Journal of Surgical Pathology. 17: 971-986. PMID 8372949 DOI: 10.1097/00000478-199310000-00002 |
0.314 |
|
| 1993 |
Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T. Efficient gene transfer into myocardium by direct injection of adenovirus vectors. Circulation Research. 73: 1202-1207. PMID 8222091 DOI: 10.1161/01.Res.73.6.1202 |
0.311 |
|
| 1993 |
Roum JH, Buhl R, McElvaney NG, Borok Z, Crystal RG. Systemic deficiency of glutathione in cystic fibrosis. Journal of Applied Physiology. 75: 2419-2424. PMID 8125859 DOI: 10.1152/Jappl.1993.75.6.2419 |
0.314 |
|
| 1993 |
Gillissen A, Birrer P, McElvaney NG, Buhl R, Vogelmeier C, Hoyt RF, Hubbard RC, Crystal RG. Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid Journal of Applied Physiology. 75: 825-832. PMID 7901193 DOI: 10.1152/Jappl.1993.75.2.825 |
0.318 |
|
| 1992 |
Lemarchand P, Jaffe HA, Danel C, Cid MC, Kleinman HK, Stratford-Perricaudet LD, Perricaudet M, Pavirani A, Lecocq JP, Crystal RG. Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 6482-6486. PMID 1631146 DOI: 10.1073/Pnas.89.14.6482 |
0.33 |
|
| 1992 |
Crystal RG. Gene therapy strategies for pulmonary disease. The American Journal of Medicine. 92. PMID 1621744 DOI: 10.1016/0002-9343(92)90607-D |
0.384 |
|
| 1992 |
Kawanami O, Matsuda K, Yoneyama H, Ferrans VJ, Crystal RG. Endothelial fenestration of the alveolar capillaries in interstitial fibrotic lung diseases. Pathology International. 42: 177-184. PMID 1570740 DOI: 10.1111/J.1440-1827.1992.Tb01669.X |
0.342 |
|
| 1992 |
Nakamura H, Yoshimura K, McElvaney NG, Crystal RG. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. Journal of Clinical Investigation. 89: 1478-1484. PMID 1569186 DOI: 10.1172/Jci115738 |
0.311 |
|
| 1992 |
Hubbard RC, McElvaney NG, Birrer P, Shak S, Robinson WW, Jolley C, Wu M, Chernick MS, Crystal RG. A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis. The New England Journal of Medicine. 326: 812-5. PMID 1538726 DOI: 10.1056/Nejm199203193261207 |
0.348 |
|
| 1992 |
Bois RMD, Kirby M, Balbi B, Saltini C, Crystal RG. T-Lymphocytes that Accumulate in the Lung in Sarcoidosis Have Evidence of Recent Stimulation of the T-Cell Antigen Receptor The American Review of Respiratory Disease. 145: 1205-1211. PMID 1533998 DOI: 10.1164/Ajrccm/145.5.1205 |
0.313 |
|
| 1992 |
Chu CS, Trapnell BC, Curristin SM, Cutting GR, Crystal RG. Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manifestations of cystic fibrosis. The Journal of Clinical Investigation. 90: 785-90. PMID 1381723 DOI: 10.1172/Jci115952 |
0.335 |
|
| 1992 |
Yoshimura K, Rosenfeld MA, Nakamura H, Scherer EM, Pavirani A, Lecocq J, Crystal RG. Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer Nucleic Acids Research. 20: 3233-3240. PMID 1377820 DOI: 10.1093/Nar/20.12.3233 |
0.399 |
|
| 1992 |
Bargon J, Trapnell BC, Chu CS, Rosenthal ER, Yoshimura K, Guggino WB, Dalemans W, Pavirani A, Lecocq JP, Crystal RG. Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations. Molecular and Cellular Biology. 12: 1872-8. PMID 1372390 DOI: 10.1128/Mcb.12.4.1872 |
0.308 |
|
| 1992 |
McElvaney NG, Nakamura H, Birrer P, Hébert CA, Wong WL, Alphonso M, Baker JB, Catalano MA, Crystal RG. Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor. The Journal of Clinical Investigation. 90: 1296-301. PMID 1357002 DOI: 10.1172/Jci115994 |
0.303 |
|
| 1992 |
Birrer P, McElvaney NG, Gillissen A, Hoyt RF, Bloedow DC, Hubbard RC, Crystal RG. Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense Journal of Applied Physiology. 73: 317-323. PMID 1354669 DOI: 10.1152/Jappl.1992.73.1.317 |
0.31 |
|
| 1992 |
Nakamura H, Yoshimura K, Bajocchi G, Trapnell BC, Pavirani A, Crystal RG. Tumor necrosis factor modulation of expression of the cystic fibrosis transmembrane conductance regulator gene. Febs Letters. 314: 366-370. PMID 1281791 DOI: 10.1016/0014-5793(92)81507-I |
0.334 |
|
| 1992 |
Yoshimura K, Crystal R. Transcriptional and posttranscriptional modulation of human neutrophil elastase gene expression. Blood. 79: 2733-2740. DOI: 10.1182/Blood.V79.10.2733.2733 |
0.327 |
|
| 1991 |
Borok Z, Gillissen A, Buhl R, Hoyt RF, Hubbard RC, Ozaki T, Rennard SI, Crystal RG. Augmentation of functional prostaglandin E levels on the respiratory epithelial surface by aerosol administration of prostaglandin E American Review of Respiratory Disease. 144: 1080-1084. PMID 1952435 DOI: 10.1164/Ajrccm/144.5.1080 |
0.355 |
|
| 1991 |
Crystal RG. Alpha 1-antitrypsin deficiency: pathogenesis and treatment. Hospital Practice. 26: 81-94. PMID 1899256 DOI: 10.1080/21548331.1991.11704145 |
0.334 |
|
| 1991 |
Tamura N, Möller DR, Balbi B, Crystal RG. Preferential Usage of the T-Cell Antigen Receptor β-Chain Constant Region Cβ1 Element by Lung T-Lymphocytes of Patients with Pulmonary Sarcoidosis The American Review of Respiratory Disease. 143: 635-639. PMID 1848052 DOI: 10.1164/Ajrccm/143.3.635 |
0.308 |
|
| 1991 |
Hamosh A, Trapnell BC, Zeitlin PL, Montrose-Rafizadeh C, Rosenstein BJ, Crystal RG, Cutting GR. Severe deficiency of cystic fibrosis transmembrane conductance regulator messenger RNA carrying nonsense mutations R553X and W1316X in respiratory epithelial cells of patients with cystic fibrosis Journal of Clinical Investigation. 88: 1880-1885. PMID 1721624 DOI: 10.1172/Jci115510 |
0.303 |
|
| 1991 |
Yoshimura K, Nakamura H, Trapnell BC, Chu C, Dakemans W, Pavirani A, Lecocq J, Crystal RG. Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin. Nucleic Acids Research. 19: 5417-5423. PMID 1717947 DOI: 10.1093/Nar/19.19.5417 |
0.346 |
|
| 1991 |
Trapnell BC, Chu CS, Paakko PK, Banks TC, Yoshimura K, Ferrans VJ, Chernick MS, Crystal RG. Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 88: 6565-9. PMID 1713683 DOI: 10.1073/Pnas.88.15.6565 |
0.35 |
|
| 1991 |
Abe T, Kobayashi N, Yoshimura K, Trapnell BC, Kim H, Hubbard RC, Brewer MT, Thompson RC, Crystal RG. Expression of the secretory leukoprotease inhibitor gene in epithelial cells. Journal of Clinical Investigation. 87: 2207-2215. PMID 1674946 DOI: 10.1172/Jci115255 |
0.353 |
|
| 1991 |
McElvaney NG, Hubbard RC, Birrer P, Chernick MS, Caplan DB, Frank MM, Crystal RG. Aerosol alpha 1-antitrypsin treatment for cystic fibrosis. Lancet. 337: 392-4. PMID 1671425 DOI: 10.1016/0140-6736(91)91167-S |
0.326 |
|
| 1991 |
Vogelmeier C, Hubbard RC, Fells GA, Schnebli H, Thompson RC, Fritz H, Crystal RG. Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor. Journal of Clinical Investigation. 87: 482-488. PMID 1671391 DOI: 10.1172/Jci115021 |
0.325 |
|
| 1991 |
Hubbard RC, Fells G, Gadek J, Pacholok S, Humes J, Crystal RG. Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages. Journal of Clinical Investigation. 88: 891-897. PMID 1653278 DOI: 10.1172/Jci115391 |
0.311 |
|
| 1990 |
Cantin AM, Fells GA, Hubbard RC, Crystal RG. Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract. Journal of Clinical Investigation. 86: 962-971. PMID 2394842 DOI: 10.1172/Jci114798 |
0.331 |
|
| 1990 |
Buhl R, Vogelmeier C, Critenden M, Hubbard RC, Hoyt RF, Wilson EM, Cantin AM, Crystal RG. Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol Proceedings of the National Academy of Sciences of the United States of America. 87: 4063-4067. PMID 2349219 DOI: 10.1073/Pnas.87.11.4063 |
0.334 |
|
| 1990 |
Nagaoka I, Trapnell BC, Crystal RG. Upregulation of platelet-derived growth factor-A and -B gene expression in alveolar macrophages of individuals with idiopathic pulmonary fibrosis Journal of Clinical Investigation. 85: 2023-2027. PMID 2347924 DOI: 10.1172/Jci114669 |
0.321 |
|
| 1990 |
Vogelmeier C, Buhl R, Hoyt RF, Wilson E, Fells GA, Hubbard RC, Schnebli HP, Thompson RC, Crystal RG. Aerosolization of recombinant SLPI to augment antineutrophil elastase protection of pulmonary epithelium. Journal of Applied Physiology (Bethesda, Md. : 1985). 69: 1843-8. PMID 2272977 DOI: 10.1152/Jappl.1990.69.5.1843 |
0.336 |
|
| 1990 |
Rom WN, Vijayan VK, Cornelius MJ, Kumaraswami V, Prabhakar R, Ottesen EA, Crystal RG. Persistent lower respiratory tract inflammation associated with interstitial lung disease in patients with tropical pulmonary eosinophilia following conventional treatment with diethylcarbamazine. The American Review of Respiratory Disease. 142: 1088-92. PMID 2173455 DOI: 10.1164/Ajrccm/142.5.1088 |
0.341 |
|
| 1990 |
Saltini C, Kirby M, Trapnell BC, Tamura N, Crystal RG. Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung. Journal of Experimental Medicine. 171: 1123-1140. PMID 2139099 DOI: 10.1084/Jem.171.4.1123 |
0.31 |
|
| 1990 |
Hubbard RC, Crystal RG. Strategies for aerosol therapy of alpha 1-antitrypsin deficiency by the aerosol route. Lung. 168: 565-578. PMID 2117165 DOI: 10.1007/Bf02718179 |
0.359 |
|
| 1990 |
Nagaoka I, Trapnell BC, Crystal RG. Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937. Journal of Clinical Investigation. 85: 448-455. PMID 1688884 DOI: 10.1172/Jci114458 |
0.303 |
|
| 1989 |
Hubbard RC, Brantly ML, Sellers SE, Mitchell ME, Crystal RG. Anti-neutrophil-elastase defenses of the lower respiratory tract in α1-antitrypsin deficiency directly augmented with an aerosol of α1-antitrypsin Annals of Internal Medicine. 111: 206-212. PMID 2787611 DOI: 10.7326/0003-4819-111-3-206 |
0.304 |
|
| 1989 |
Hubbard RC, Casolaro MA, Mitchell M, Sellers SE, Arabia F, Matthay MA, Crystal RG. Fate of aerosolized recombinant DNA-produced alpha 1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance Proceedings of the National Academy of Sciences of the United States of America. 86: 680-684. PMID 2783491 DOI: 10.1073/Pnas.86.2.680 |
0.323 |
|
| 1989 |
Nutman TB, Vijayan VK, Pinkston P, Kumaraswami V, Steel C, Crystal RG, Ottesen EA. Tropical pulmonary eosinophilia: analysis of antifilarial antibody localized to the lung. The Journal of Infectious Diseases. 160: 1042-50. PMID 2685125 DOI: 10.1093/Infdis/160.6.1042 |
0.305 |
|
| 1989 |
Crystal RG, Brantly ML, Hubbard RC, Curiel DT, States DJ, Holmes MD. The alpha 1-antitrypsin gene and its mutations. Clinical consequences and strategies for therapy. Chest. 95: 196-208. PMID 2642408 DOI: 10.1378/Chest.95.1.196 |
0.32 |
|
| 1989 |
Fouret P, Bois RMd, Bernaudin JF, Takahashi H, Ferrans VJ, Crystal RG. Expression of the neutrophil elastase gene during human bone marrow cell differentiation. Journal of Experimental Medicine. 169: 833-845. PMID 2538548 DOI: 10.1084/Jem.169.3.833 |
0.309 |
|
| 1989 |
Spurzem JR, Saltini C, Kirby M, Konishi K, Crystal RG. Expression of HLA class II genes in alveolar macrophages of patients with sarcoidosis. The American Review of Respiratory Disease. 140: 89-94. PMID 2526608 DOI: 10.1164/Ajrccm/140.1.89 |
0.309 |
|
| 1989 |
Saltini C, Winestock K, Kirby M, Pinkston P, Crystal RG. Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells. The New England Journal of Medicine. 320: 1103-1109. PMID 2469014 DOI: 10.1056/Nejm198904273201702 |
0.312 |
|
| 1988 |
Rennard SI, Bitterman PB, Ozaki T, Rom WN, Crystal RG. Colchicine suppresses the release of fibroblast growth factors from alveolar macrophages in vitro. The basis of a possible therapeutic approach ot the fibrotic disorders. The American Review of Respiratory Disease. 137: 181-5. PMID 3337460 DOI: 10.1164/Ajrccm/137.1.181 |
0.329 |
|
| 1988 |
Hance AJ, Saltini C, Crystal RG. Does de novo immunoglobulin synthesis occur on the epithelial surface of the human lower respiratory tract The American Review of Respiratory Disease. 137: 17-24. PMID 3276252 DOI: 10.1164/Ajrccm/137.1.17 |
0.364 |
|
| 1988 |
Martinet Y, Pinkston P, Saltini C, Spurzem J, Müller-Quernheim J, Crystal RG. Evaluation of the in vitro and in vivo effects of cyclosporine on the lung T-lymphocyte alveolitis of active pulmonary sarcoidosis. The American Review of Respiratory Disease. 138: 1242-1248. PMID 3264483 DOI: 10.1164/Ajrccm/138.5.1242 |
0.324 |
|
| 1988 |
Brantly ML, Paul LD, Miller BH, Falk RT, Wu M, Crystal RG. Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms. The American Review of Respiratory Disease. 138: 327-36. PMID 3264124 DOI: 10.1164/Ajrccm/138.2.327 |
0.326 |
|
| 1988 |
Saltini C, Hemler ME, Crystal RG. T lymphocytes compartmentalized on the epithelial surface of the lower respiratory tract express the very late activation antigen complex VLA-1 Clinical Immunology and Immunopathology. 46: 221-233. PMID 3257425 DOI: 10.1016/0090-1229(88)90185-7 |
0.318 |
|
| 1988 |
Martinet Y, Yamauchi K, Crystal RG. Differential expression of the tumor necrosis factor/cachectin gene by blood and lung mononuclear phagocytes. The American Review of Respiratory Disease. 138: 659-665. PMID 3202418 DOI: 10.1164/Ajrccm/138.3.659 |
0.307 |
|
| 1988 |
Rom WN, Bitterman PB, Rennard SI, Cantin A, Crystal RG. Characterization of the lower respiratory tract inflammation of nonsmoking individuals with interstitial lung disease associated with chronic inhalation of inorganic dusts. The American Review of Respiratory Disease. 136: 1429-34. PMID 2825569 DOI: 10.1164/Ajrccm/136.6.1429 |
0.345 |
|
| 1988 |
Moller D, Konishi K, Kirby M, Balbi B, Crystal RG. Bias toward use of a specific T cell receptor beta-chain variable region in a subgroup of individuals with sarcoidosis. Journal of Clinical Investigation. 82: 1183-1191. PMID 2459159 DOI: 10.1172/Jci113715 |
0.31 |
|
| 1988 |
Hubbard RC, Crystal RG. Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiency The American Journal of Medicine. 84: 52-62. DOI: 10.1016/S0002-9343(88)80071-8 |
0.335 |
|
| 1988 |
Brantly M, Nukiwa T, Crystal RG. Molecular basis of alpha-1-antitrypsin deficiency The American Journal of Medicine. 84: 13-31. DOI: 10.1016/S0002-9343(88)80066-4 |
0.314 |
|
| 1988 |
Hubbard RC, Sellers S, Czerski D, Stephens L, Crystal RG. Biochemical efficacy and safety of monthly augmentation therapy for alpha 1-antitrypsin deficiency. Jama. 260: 1259-1264. DOI: 10.1001/Jama.1988.03410090091037 |
0.341 |
|
| 1987 |
Yamauchi K, Martinet Y, Crystal RG. Modulation of fibronectin gene expression in human mononuclear phagocytes. Journal of Clinical Investigation. 80: 1720-1727. PMID 3680524 DOI: 10.1172/Jci113263 |
0.314 |
|
| 1987 |
O'Donnell K, Keogh B, Cantin A, Crystal RG. Pharmacologic suppression of the neutrophil component of the alveolitis in idiopathic pulmonary fibrosis. The American Review of Respiratory Disease. 136: 288-292. PMID 3619187 DOI: 10.1164/Ajrccm/136.2.288 |
0.341 |
|
| 1987 |
Martinet Y, Rom WN, Grotendorst GR, Martin GR, Crystal RG. Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis The New England Journal of Medicine. 317: 202-209. PMID 3600711 DOI: 10.1056/Nejm198707233170404 |
0.339 |
|
| 1987 |
Garver RI, Chytil A, Courtney M, Crystal RG. Clonal gene therapy: transplanted mouse fibroblast clones express human alpha 1-antitrypsin gene in vivo. Science. 237: 762-764. PMID 3497452 DOI: 10.1126/Science.3497452 |
0.332 |
|
| 1987 |
Spurzem JR, Saltini C, Rom W, Winchester RJ, Crystal RG. Mechanisms of Macrophage Accumulation in the Lungs of Asbestos-Exposed Subjects The American Review of Respiratory Disease. 136: 276-280. PMID 3304044 DOI: 10.1164/Ajrccm/136.2.276 |
0.319 |
|
| 1987 |
Cantin AM, North SL, Hubbard RC, Crystal RG. Normal alveolar epithelial lining fluid contains high levels of glutathione. Journal of Applied Physiology. 63: 152-157. PMID 3040659 DOI: 10.1152/Jappl.1987.63.1.152 |
0.334 |
|
| 1987 |
Cantin AM, North SL, Fells GA, Hubbard RC, Crystal RG. Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. Journal of Clinical Investigation. 79: 1665-1673. PMID 3034979 DOI: 10.1172/Jci113005 |
0.339 |
|
| 1987 |
Garver RI, Chytil A, Karlsson S, Fells GA, Brantly ML, Courtney M, Kantoff PW, Nienhuis AW, Anderson WF, Crystal RG. Production of glycosylated physiologically 'normal' human α1-antitrypsin by mouse fibroblasts modified by insertion of a human α1-antitrypsin cDNA using a retroviral vector Proceedings of the National Academy of Sciences of the United States of America. 84: 1050-1054. PMID 3029759 DOI: 10.1073/Pnas.84.4.1050 |
0.522 |
|
| 1986 |
Martinet Y, Bitterman PB, Mornex JF, Grotendorst GR, Martin GR, Crystal RG. Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity. Nature. 319: 158-60. PMID 3941744 DOI: 10.1038/319158A0 |
0.32 |
|
| 1986 |
Mornex JF, Martinet Y, Yamauchi K, Bitterman PB, Grotendorst GR, Chytil-Weir A, Martin GR, Crystal RG. Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages. The Journal of Clinical Investigation. 78: 61-6. PMID 3722386 DOI: 10.1172/Jci112574 |
0.329 |
|
| 1986 |
Crystal RG, Reynolds HY, Kalica AR. Bronchoalveolar Lavage: The Report of an International Conference Chest. 90: 122-131. PMID 3720374 DOI: 10.1378/Chest.90.1.122 |
0.335 |
|
| 1986 |
Bitterman PB, Rennard SI, Keogh BA, Wewers MD, Adelberg S, Crystal RG. Familial idiopathic pulmonary fibrosis. Evidence of lung inflammation in unaffected family members. The New England Journal of Medicine. 314: 1343-7. PMID 3702942 DOI: 10.1056/Nejm198605223142103 |
0.317 |
|
| 1986 |
Saltini C, Spurzem JR, Lee JJ, Pinkston P, Crystal RG. Spontaneous release of interleukin 2 by lung T lymphocytes in active pulmonary sarcoidosis is primarily from the Leu3+DR+ T cell subset. Journal of Clinical Investigation. 77: 1962-1970. PMID 3486888 DOI: 10.1172/Jci112525 |
0.323 |
|
| 1986 |
Mornex JF, Chytil-Weir A, Martinet Y, Courtney M, LeCocq JP, Crystal RG. Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals. Journal of Clinical Investigation. 77: 1952-1961. PMID 3486887 DOI: 10.1172/Jci112524 |
0.346 |
|
| 1986 |
Bitterman PB, Wewers MD, Rennard SI, Adelberg S, Crystal RG. Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. The Journal of Clinical Investigation. 77: 700-8. PMID 3081573 DOI: 10.1172/Jci112364 |
0.326 |
|
| 1985 |
Rossi GA, Bitterman PB, Rennard SI, Ferrans VJ, Crystal RG. Evidence for chronic inflammation as a component of the interstitial lung disease associated with progressive systemic sclerosis. The American Review of Respiratory Disease. 131: 612-7. PMID 3994157 DOI: 10.1164/Arrd.1985.131.4.612 |
0.342 |
|
| 1985 |
Rossi GA, Hunninghake GW, Kawanami O, Ferrans VJ, Hansen CT, Crystal RG. Motheaten mice--an animal model with an inherited form of interstitial lung disease. The American Review of Respiratory Disease. 131: 150-158. PMID 3966703 DOI: 10.1164/Arrd.1985.131.1.150 |
0.318 |
|
| 1985 |
Venet A, Hance AJ, Saltini C, Robinson BW, Crystal RG. Enhanced alveolar macrophage-mediated antigen-induced T-lymphocyte proliferation in sarcoidosis. Journal of Clinical Investigation. 75: 293-301. PMID 3871200 DOI: 10.1172/Jci111688 |
0.313 |
|
| 1984 |
Bitterman PB, Saltzman LE, Adelberg S, Ferrans VJ, Crystal RG. Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung. The Journal of Clinical Investigation. 74: 460-9. PMID 6746904 DOI: 10.1172/Jci111443 |
0.325 |
|
| 1984 |
Robinson BW, Pinkston P, Crystal RG. Natural killer cells are present in the normal human lung but are functionally impotent. Journal of Clinical Investigation. 74: 942-950. PMID 6590570 DOI: 10.1172/Jci111513 |
0.34 |
|
| 1984 |
Lacronique JG, Rennard SI, Bitterman PB, Ozaki T, Crystal RG. Alveolar macrophages in idiopathic pulmonary fibrosis have glucocorticoid receptors, but glucocorticoid therapy does not suppress alveolar macrophage release of fibronectin and alveolar macrophage derived growth factor. The American Review of Respiratory Disease. 130: 450-6. PMID 6476595 DOI: 10.1164/Arrd.1984.130.3.450 |
0.303 |
|
| 1984 |
Berg RA, Schwartz ML, Rome LH, Crystal RG. Lysosomal function in the degradation of defective collagen in cultured lung fibroblasts. Biochemistry. 23: 2134-2138. PMID 6375717 DOI: 10.1021/Bi00305A005 |
0.305 |
|
| 1984 |
Crystal RG, Bitterman PB, Rennard SI, Hance AJ, Keogh BA. Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts). The New England Journal of Medicine. 310: 154-66. PMID 6361560 DOI: 10.1056/Nejm198401193100304 |
0.315 |
|
| 1984 |
Rennard SI, Bitterman PB, Crystal RG. Response of the lower respiratory tract to injury. Mechanisms of repair of the parenchymal cells of the alveolar wall. Chest. 84: 735-9. PMID 6357653 DOI: 10.1378/Chest.84.6.735 |
0.338 |
|
| 1984 |
Davis WB, Fells GA, Sun XH, Gadek JE, Venet A, Crystal RG. Eosinophil-mediated injury to lung parenchymal cells and interstitial matrix. A possible role for eosinophils in chronic inflammatory disorders of the lower respiratory tract. Journal of Clinical Investigation. 74: 269-278. PMID 6330175 DOI: 10.1172/Jci111411 |
0.371 |
|
| 1984 |
Gadek JE, Fells GA, Zimmerman RL, Crystal RG. Role of connective tissue proteases in the pathogenesis of chronic inflammatory lung disease. Environmental Health Perspectives. 55: 297-306. PMID 6329673 DOI: 10.1289/Ehp.8455297 |
0.33 |
|
| 1983 |
Davis WB, Rennard SI, Bitterman PB, Crystal RG. Pulmonary oxygen toxicity. Early reversible changes in human alveolar structures induced by hyperoxia. The New England Journal of Medicine. 309: 878-83. PMID 6888481 DOI: 10.1056/Nejm198310133091502 |
0.315 |
|
| 1983 |
Berg RA, Steinmann B, Rennard SI, Crystal RG. Ascorbate deficiency results in decreased collagen production: under-hydroxylation of proline leads to increased intracellular degradation. Archives of Biochemistry and Biophysics. 226: 681-6. PMID 6639074 DOI: 10.1016/0003-9861(83)90338-7 |
0.301 |
|
| 1983 |
Bitterman PB, Adelberg S, Crystal RG. Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders. The Journal of Clinical Investigation. 72: 1801-13. PMID 6630527 DOI: 10.1172/Jci111140 |
0.33 |
|
| 1983 |
Fukuda Y, Ferrans VJ, Crystal RG. The development of alveolar septa in fetal sheep lung. An ultrastructural and immunohistochemical study. American Journal of Anatomy. 167: 405-439. PMID 6624688 DOI: 10.1002/Aja.1001670402 |
0.306 |
|
| 1983 |
Keogh BA, Hunninghake GW, Line BR, Crystal R. The alveolitis of pulmonary sarcoidosis. Evaluation of natural history and alveolitis-dependent changes in lung function The American Review of Respiratory Disease. 128: 256-265. PMID 6603804 DOI: 10.1164/Arrd.1983.128.2.256 |
0.32 |
|
| 1983 |
Pinkston P, Bitterman PB, Crystal RG. Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis. The New England Journal of Medicine. 308: 793-800. PMID 6601235 DOI: 10.1056/Nejm198304073081401 |
0.331 |
|
| 1983 |
Gadek JE, Crystal RG. Experience with replacement therapy in the destructive lung disease associated with severe alpha-1-antitrypsin deficiency. The American Review of Respiratory Disease. 127. PMID 6600893 DOI: 10.1164/Arrd.1983.127.2P2.S45 |
0.308 |
|
| 1983 |
Bitterman P, Rennard S, Adelberg S, Crystal RG. Role of Fibronectin in Fibrotic Lung Disease: A Growth Factor for Human Lung Fibroblasts Chest. 83. DOI: 10.1378/Chest.83.5_Supplement.96S |
0.323 |
|
| 1983 |
Davis W, Rennard S, Bitterman P, Gadek J, Sun X, Wewers M, Keogh B, Crystal R. Pulmonary Oxygen Toxicity Chest. 83: 35S. DOI: 10.1378/Chest.83.5_Supplement.35S |
0.307 |
|
| 1982 |
Schoenberger CI, Hunninghake GW, Kawanami O, Ferrans VJ, Crystal RG. Role of alveolar macrophages in asbestosis: modulation of neutrophil migration to the lung after acute asbestos exposure. Thorax. 37: 803-809. PMID 7163997 DOI: 10.1136/Thx.37.11.803 |
0.315 |
|
| 1982 |
Davidson JM, Crystal RG. The molecular aspects of elastin gene expression. The Journal of Investigative Dermatology. 79: 133s-137s. PMID 7086184 DOI: 10.1038/Jid.1982.25 |
0.311 |
|
| 1982 |
Rennard SI, Crystal RG. Fibronectin in human bronchopulmonary lavage fluid. Elevation in patients with interstitial lung disease. Journal of Clinical Investigation. 69: 113-122. PMID 7054232 DOI: 10.1172/Jci110421 |
0.345 |
|
| 1982 |
Rennard SI, Hunninghake GW, Bitterman PB, Crystal RG. Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. Proceedings of the National Academy of Sciences of the United States of America. 78: 7147-51. PMID 6947279 DOI: 10.1073/Pnas.78.11.7147 |
0.352 |
|
| 1982 |
Tolstoshev P, Crystal RG. The collagen alpha-2 chain gene. Journal of Investigative Dermatology. 79: 60-64. DOI: 10.1038/Jid.1982.11 |
0.31 |
|
| 1981 |
Shibahara SU, Davidson JM, Smith K, Crystal RG. Modulation of tropoelastin production and elastin messenger ribonucleic acid activity in developing sheep lung. Biochemistry. 20: 6577-84. PMID 7306525 DOI: 10.1021/Bi00526A009 |
0.307 |
|
| 1981 |
nd WJM, Gadek JE, Hunninghake GW, Crystal RG. Oxidant injury of lung parenchymal cells. Journal of Clinical Investigation. 68: 1277-1288. PMID 7298852 DOI: 10.1172/Jci110374 |
0.323 |
|
| 1981 |
Hunninghake GW, Gadek JE, Lawley TJ, Crystal RG. Mechanisms of neutrophil accumulation in the lungs of patients with idiopathic pulmonary fibrosis. The Journal of Clinical Investigation. 68: 259-69. PMID 7251862 DOI: 10.1172/Jci110242 |
0.313 |
|
| 1981 |
Bitterman P, Rennard S, Schoenberger C, Crystal R. Asbestos stimulates alveolar macrophages to release a factor causing human lung fibroblasts to replicate. Chest. 80: 38-9. PMID 7249735 DOI: 10.1378/Chest.80.1_Supplement.38S |
0.31 |
|
| 1981 |
Crystal RG, Rennard SI. Pulmonary Connective Tissue and Environmental Lung Disease Chest. 80: 33. PMID 7249734 DOI: 10.1378/Chest.80.1_Supplement.33S-A |
0.307 |
|
| 1981 |
Hunninghake GW, Davidson JM, Rennard S, Szapiel S, Gadek JE, Crystal RG. Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema. Science (New York, N.Y.). 212: 925-7. PMID 7233186 DOI: 10.1126/Science.7233186 |
0.304 |
|
| 1981 |
Crystal RG, Gadek JE, Ferrans VJ, Fulmer JD, Line BR, Hunninghake GW. Interstitial lung disease: Current concepts of pathogenesis, staging and therapy The American Journal of Medicine. 70: 542-568. PMID 7011012 DOI: 10.1016/0002-9343(81)90577-5 |
0.366 |
|
| 1981 |
Crystal RG, Roberts WC, Hunninghake GW, Gadek JE, Fulmer JD, Line BR. Pulmonary Sarcoidosis: A Disease Characterized and Perpetuated by Activated Lung T-Lymphocytes Annals of Internal Medicine. 94: 73-94. PMID 7004303 DOI: 10.7326/0003-4819-94-1-73 |
0.322 |
|
| 1981 |
Hunninghake GW, Crystal RG. Mechanisms of hypergammaglobulinemia in pulmonary sarcoidosis. Site of increased antibody production and role of T lymphocytes. Journal of Clinical Investigation. 67: 86-92. PMID 6969734 DOI: 10.1172/Jci110036 |
0.347 |
|
| 1981 |
Hunninghake GW, Crystal RG. Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. The New England Journal of Medicine. 305: 429-434. PMID 6454846 DOI: 10.1056/Nejm198108203050804 |
0.337 |
|
| 1980 |
Rosenberg DM, Weinberger SE, Fulmer JD, Flye MW, Fauci AS, Crystal RG. Functional correlates of lung involvement in Wegener's granulomatosis. Use of pulmonary function tests in staging and follow-up. The American Journal of Medicine. 69: 387-394. PMID 7416186 DOI: 10.1016/0002-9343(80)90009-1 |
0.318 |
|
| 1980 |
Gadek JE, Hunninghake GW, Fells GA, Zimmerman RL, Keogh BA, Crystal RG. Evaluation of the protease-antiprotease theory of human destructive lung disease. Bulletin EuropéEn De Physiopathologie Respiratoire. 16: 27-41. PMID 7013877 DOI: 10.1016/B978-0-08-027379-2.50005-3 |
0.358 |
|
| 1980 |
Hunninghake GW, Gadek JE, Szapiel SV, Strumpf IJ, Kawanami O, Ferrans VJ, Keogh BA, Crystal RG. Chapter 6 The Human Alveolar Macrophage Methods in Cell Biology. 21: 95-112. PMID 6997688 DOI: 10.1016/S0091-679X(08)60760-8 |
0.324 |
|
| 1980 |
Bradley KH, Kawanami O, Ferrans VJ, Crystal RG. Chapter 3 The Fibroblast of Human Lung Alveolar Structures: A Differentiated Cell with a Major Role in Lung Structure and Function Methods in Cell Biology. 21: 37-64. PMID 6997687 DOI: 10.1016/S0091-679X(08)60757-8 |
0.335 |
|
| 1980 |
Hunninghake GW, Gadek JE, Fales HM, Crystal RG. Human Alveolar Macrophage-derived Chemotactic Factor for Neutrophils: STIMULI AND PARTIAL CHARACTERIZATION Journal of Clinical Investigation. 66: 473-483. PMID 6995485 DOI: 10.1172/Jci109878 |
0.322 |
|
| 1980 |
Gadek JE, Keogh BA, Crystal R. Opportunities for the specific therapy of destructive lung disease. Bulletin EuropéEn De Physiopathologie Respiratoire. 16: 389-398. PMID 6971680 DOI: 10.1016/B978-0-08-027379-2.50041-7 |
0.344 |
|
| 1980 |
Rossi GA, Hunninghake GW, Szapiel SV, Gadek JE, Fulmer JD, Kawanami O, Ferrans VJ, Crystal RG. The tight-skin mouse: an animal model of inherited emphysema. Bulletin EuropéEn De Physiopathologie Respiratoire. 157-166. PMID 6971670 DOI: 10.1016/B978-0-08-027379-2.50016-8 |
0.35 |
|
| 1980 |
Hunninghake GW, Gadek JE, Young RC, Kawanami O, Ferrans VJ, Crystal RG. Maintenance of Granuloma Formation in Pulmonary Sarcoidosis by T Lymphocytes within the Lung The New England Journal of Medicine. 302: 594-598. PMID 6965420 DOI: 10.1056/Nejm198003133021102 |
0.339 |
|
| 1979 |
Fulmer JD, Roberts WC, Gal ERv, Crystal RG. Morphologic-physiologic correlates of the severity of fibrosis and degree of cellularity in idiopathic pulmonary fibrosis. Journal of Clinical Investigation. 63: 665-676. PMID 438328 DOI: 10.1172/Jci109349 |
0.305 |
|
| 1979 |
Gadek JE, Fells GA, Crystal R. Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans. Science. 206: 1315-1316. PMID 316188 DOI: 10.1126/Science.316188 |
0.307 |
|
| 1979 |
Bernardo J, Hunninghake GW, Gadek JE, Ferrans VJ, Crystal RG. Acute hypersensitivity pneumonitis: serial changes in lung lymphocyte subopulations after exposure to antigen. The American Review of Respiratory Disease. 120: 985-994. PMID 315742 DOI: 10.1164/Arrd.1979.120.5.985 |
0.343 |
|
| 1978 |
Crystal RG, Fulmer JD, Baum BJ, Bernardo J, Bradley KH, Bruel SD, Elson NA, Fells GA, Ferrans VJ, Gadek JE, Hunninghake GW, Kawanami O, Kelman JA, Line BR, McDonald JA, et al. Cells, collagen and idiopathic pulmonary fibrosis. Lung. 155: 199-224. PMID 703380 DOI: 10.1007/Bf02730694 |
0.352 |
|
| 1977 |
Reynolds HY, Fulmer JD, Kazmierowski JA, Roberts WC, Frank MM, Crystal RG. Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. Journal of Clinical Investigation. 59: 165-175. PMID 830661 DOI: 10.1172/Jci108615 |
0.344 |
|
| 1976 |
Hance AJ, Horwitz AL, Cowan MJ, Elson NA, Collins JF, Bienkowski RS, Bradley KH, McConnell-Breul S, Wagner WM, Crystal RG. Biochemical Approaches to the Investigation of Fibrotic Lung Disease Chest. 69: 257-261. PMID 1248297 DOI: 10.1378/Chest.69.2_Supplement.257 |
0.301 |
|
| 1976 |
Hance AJ, Bradley K, Crystal RG. Lung collagen heterogeneity. Synthesis of type I and type III collagen by rabbit and human lung cells in culture Journal of Clinical Investigation. 57: 102-111. PMID 1245595 DOI: 10.1172/Jci108250 |
0.323 |
|
| 1976 |
Crystal RG, Fulmer JD, Roberts WC, Moss ML, Line BR, Reynolds HY. Idiopathic Pulmonary Fibrosis: Clinical, Histologic, Radiographic, Physiologic, Scintigraphic, Cytologic, and Biochemical Aspects Annals of Internal Medicine. 85: 769-788. PMID 793466 DOI: 10.7326/0003-4819-85-6-769 |
0.311 |
|
| 1976 |
Kravis TC, Ahmed A, Brown TE, Fulmer JD, Crystal RG. Pathogenic mechanisms in pulmonary fibrosis. Collagen induced migration inhibition factor production and cytotoxicity mediated by lymphocytes Journal of Clinical Investigation. 58: 1223-1232. PMID 62760 DOI: 10.1172/Jci108576 |
0.364 |
|
| 1975 |
Cowan MJ, Crystal RG. Lung growth after unilateral pneumonectomy: quantitation of collagen synthesis and content. The American Review of Respiratory Disease. 111: 267-277. PMID 1119740 DOI: 10.1164/Arrd.1975.111.3.267 |
0.338 |
|
| 1975 |
Bradley K, McConnell Breul S, Crystal RG. Collagen in the human lung. Quantitation of rates of synthesis and partial characterization of composition Journal of Clinical Investigation. 55: 543-550. PMID 163849 DOI: 10.1172/Jci107961 |
0.318 |
|
| 1975 |
Crystal RG, Bradley KH, McConnell-Breu SD, Collins JF, Hanca AJ, Cowan MJ. Collagen in the lung: development of a technology applicable to human lung disease. Chest. 67: 30. DOI: 10.1378/Chest.67.2_Supplement.30S |
0.328 |
|
| 1972 |
Crystal RG, Nienhuis AW, Prichard PM, Picciano D, Elson NA, Merrick WC, Graf H, Shafritz DA, Laycock DG, Last JA, Anderson WF. Initiation of globin synthesis. Febs Letters. 24: 310-314. PMID 11946695 DOI: 10.1016/0014-5793(72)80379-X |
0.474 |
|
| 1972 |
Crystal RG, Nienhuis AW, Prichard PM, Picciano D, Elson NA, Merrick WC, Graf H, Shafritz DA, Laycock DG, Last JA, Anderson WF. Initiation of globin synthesis Febs Letters. 24: 310-314. DOI: 10.1016/0014-5793(72)80379-X |
0.427 |
|
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