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R. Michael Linden, PhD - Publications

Affiliations: 
King's College London, London, UK 
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52/387 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Araujo VG, Dias MS, Hauswirth WW, Linden R, Petrs-Silva H. rAAV-compatible human mini promoters enhance transgene expression in rat retinal ganglion cells. Experimental Eye Research. 239: 109758. PMID 38123011 DOI: 10.1016/j.exer.2023.109758  0.485
2022 Lani-Louzada R, Marra C, Dias MS, de Araújo VG, Abreu CA, Ribas VT, Adesse D, Allodi S, Chiodo V, Hauswirth W, Petrs-Silva H, Linden R. Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration. Investigative Ophthalmology & Visual Science. 63: 5. PMID 35103748 DOI: 10.1167/iovs.63.2.5  0.46
2019 Dias MS, Araujo VG, Vasconcelos T, Li Q, Hauswirth WW, Linden R, Petrs-Silva H. Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat. Gene Therapy. PMID 31562387 DOI: 10.1038/S41434-019-0100-9  0.449
2018 Agúndez L, Zárate-Pérez F, Meier AF, Bardelli M, Llosa M, Escalante CR, Linden RM, Henckaerts E. Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus. Plos One. 13: e0200841. PMID 30016371 DOI: 10.1371/Journal.Pone.0200841  0.365
2018 Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, ... ... Linden RM, et al. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency. Brain : a Journal of Neurology. PMID 29788236 DOI: 10.1093/Brain/Awy126  0.423
2018 Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E. Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581310 DOI: 10.1073/Pnas.1721883115  0.486
2017 Cabral-Miranda F, Nicoloso-Simões E, Adão-Novaes J, Chiodo V, Hauswirth WW, Linden R, Chiarini LB, Petrs-Silva H. rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 392-400. PMID 28153090 DOI: 10.1016/J.Ymthe.2016.11.017  0.444
2017 Seyffert M, Glauser DL, Schraner EM, de Oliveira AP, Mansilla-Soto J, Vogt B, Büning H, Linden RM, Ackermann M, Fraefel C. Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. Plos One. 12: e0170908. PMID 28125695 DOI: 10.1371/Journal.Pone.0170908  0.487
2016 Bardelli M, Zárate-Pérez F, Agúndez L, Linden RM, Escalante CR, Henckaerts E. Identification of a functionally relevant AAV Rep68 oligomeric interface. Journal of Virology. PMID 27170758 DOI: 10.1128/Jvi.00356-16  0.396
2015 Petri K, Gabriel R, Agundez L, Fronza R, Afzal S, Kaeppel C, Linden RM, Henckaerts E, Schmidt M. Presence of a trs-Like Motif Promotes Rep-Mediated Wild-Type Adeno-Associated Virus Type 2 Integration. Journal of Virology. 89: 7428-32. PMID 25972561 DOI: 10.1128/Jvi.00426-15  0.442
2014 Cabral Miranda F, Adão-Novaes J, Hauswirth WW, Linden R, Petrs-Silva H, Chiarini LB. CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system. Frontiers in Cellular Neuroscience. 8: 438. PMID 25620910 DOI: 10.3389/Fncel.2014.00438  0.388
2014 Dutheil N, Smith SC, Agúndez L, Vincent-Mistiaen ZI, Escalante CR, Linden RM, Henckaerts E. Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter. Journal of Virology. 88: 8227-41. PMID 24829354 DOI: 10.1128/Jvi.00412-14  0.506
2014 Petri K, Fronza R, Gabriel R, Käppel C, Nowrouzi A, Linden RM, Henckaerts E, Schmidt M. Comparative next-generation sequencing of adeno-associated virus inverted terminal repeats. Biotechniques. 56: 269-73. PMID 24806228 DOI: 10.2144/000114170  0.306
2013 Petrs-Silva H, Linden R. Advances in recombinant adeno-associated viral vectors for gene delivery. Current Gene Therapy. 13: 335-45. PMID 24060313 DOI: 10.2174/15665232113136660028  0.305
2013 González-Prieto C, Agúndez L, Linden RM, Llosa M. HUH site-specific recombinases for targeted modification of the human genome. Trends in Biotechnology. 31: 305-12. PMID 23545167 DOI: 10.1016/j.tibtech.2013.02.002  0.396
2013 Zarate-Perez F, Mansilla-Soto J, Bardelli M, Burgner JW, Villamil-Jarauta M, Kekilli D, Samso M, Linden RM, Escalante CR. Oligomeric properties of adeno-associated virus Rep68 reflect its multifunctionality. Journal of Virology. 87: 1232-41. PMID 23152528 DOI: 10.1128/Jvi.02441-12  0.388
2012 Kohlbrenner E, Henckaerts E, Rapti K, Gordon RE, Linden RM, Hajjar RJ, Weber T. Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels. Human Gene Therapy Methods. 23: 198-203. PMID 22816378 DOI: 10.1089/Hgtb.2012.049  0.393
2012 Zarate-Perez F, Bardelli M, Burgner JW, Villamil-Jarauta M, Das K, Kekilli D, Mansilla-Soto J, Linden RM, Escalante CR. The interdomain linker of AAV-2 Rep68 is an integral part of its oligomerization domain: role of a conserved SF3 helicase residue in oligomerization. Plos Pathogens. 8: e1002764. PMID 22719256 DOI: 10.1371/Journal.Ppat.1002764  0.36
2011 Weitzman MD, Linden RM. Adeno-associated virus biology. Methods in Molecular Biology (Clifton, N.J.). 807: 1-23. PMID 22034024 DOI: 10.1007/978-1-61779-370-7_1  0.473
2010 Henckaerts E, Linden RM. Adeno-associated virus: a key to the human genome? Future Virology. 5: 555-574. PMID 21212830 DOI: 10.2217/Fvl.10.48  0.475
2010 Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden RM, Radu A, Grundke-Iqbal I, Iqbal K. The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4420-32. PMID 20651003 DOI: 10.1096/Fj.10-158477  0.304
2010 Linden RM, Berns KI. Viral Vectors for Gene Therapy Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0274  0.643
2009 Dutheil N, Henckaerts E, Kohlbrenner E, Linden RM. Transcriptional analysis of the adeno-associated virus integration site. Journal of Virology. 83: 12512-25. PMID 19759129 DOI: 10.1128/Jvi.01754-09  0.458
2009 Mansilla-Soto J, Yoon-Robarts M, Rice WJ, Arya S, Escalante CR, Linden RM. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68. Plos Pathogens. 5: e1000513. PMID 19593381 DOI: 10.1371/Journal.Ppat.1000513  0.427
2009 Henckaerts E, Dutheil N, Zeltner N, Kattman S, Kohlbrenner E, Ward P, Clément N, Rebollo P, Kennedy M, Keller GM, Linden RM. Site-specific integration of adeno-associated virus involves partial duplication of the target locus. Proceedings of the National Academy of Sciences of the United States of America. 106: 7571-6. PMID 19372372 DOI: 10.1073/Pnas.0806821106  0.465
2007 Ward P, Clément N, Linden RM. cis effects in adeno-associated virus type 2 replication. Journal of Virology. 81: 9976-89. PMID 17626079 DOI: 10.1128/Jvi.00630-07  0.476
2007 Hirosue S, Senn K, Clément N, Nonnenmacher M, Gigout L, Linden RM, Weber T. Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction. Virology. 367: 10-8. PMID 17588632 DOI: 10.1016/J.Virol.2007.05.009  0.341
2007 Glauser DL, Strasser R, Laimbacher AS, Saydam O, Clément N, Linden RM, Ackermann M, Fraefel C. Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction. Journal of Virology. 81: 4732-43. PMID 17314170 DOI: 10.1128/Jvi.02476-06  0.47
2006 Vasileva A, Linden RM, Jessberger R. Homologous recombination is required for AAV-mediated gene targeting. Nucleic Acids Research. 34: 3345-60. PMID 16822856 DOI: 10.1093/Nar/Gkl455  0.409
2005 Zhang N, Clément N, Chen D, Fu S, Zhang H, Rebollo P, Linden RM, Bromberg JS. Transduction of pancreatic islets with pseudotyped adeno-associated virus: effect of viral capsid and genome conversion. Transplantation. 80: 683-90. PMID 16177645 DOI: 10.1097/01.Tp.0000173381.97556.0D  0.435
2005 Glauser DL, Saydam O, Balsiger NA, Heid I, Linden RM, Ackermann M, Fraefel C. Four-dimensional visualization of the simultaneous activity of alternative adeno-associated virus replication origins. Journal of Virology. 79: 12218-30. PMID 16160148 DOI: 10.1128/Jvi.79.19.12218-12230.2005  0.483
2005 Gigout L, Rebollo P, Clement N, Warrington KH, Muzyczka N, Linden RM, Weber T. Altering AAV tropism with mosaic viral capsids. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 856-65. PMID 15922956 DOI: 10.1016/J.Ymthe.2005.03.005  0.408
2005 Petrs-Silva H, Chiodo V, Chiarini LB, Hauswirth WW, Linden R. Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 38: 375-9. PMID 15761617 DOI: 10.1590/S0100-879X2005000300008  0.467
2005 Henckaerts E, Zeltner N, Kattman S, Dutheil N, Ward P, Kennedy M, Clement N, Rebollo P, Keller G, Linden RM. 20. Targeted Gene Delivery to Embryonic Stem Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.023  0.391
2004 Yoon-Robarts M, Blouin AG, Bleker S, Kleinschmidt JA, Aggarwal AK, Escalante CR, Linden RM. Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2. The Journal of Biological Chemistry. 279: 50472-81. PMID 15371437 DOI: 10.1074/Jbc.M403900200  0.382
2004 James JA, Aggarwal AK, Linden RM, Escalante CR. Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases. Proceedings of the National Academy of Sciences of the United States of America. 101: 12455-60. PMID 15310852 DOI: 10.1073/Pnas.0403454101  0.333
2004 Dutheil N, Yoon-Robarts M, Ward P, Henckaerts E, Skrabanek L, Berns KI, Campagne F, Linden RM. Characterization of the mouse adeno-associated virus AAVS1 ortholog. Journal of Virology. 78: 8917-21. PMID 15280500 DOI: 10.1128/Jvi.78.16.8917-8921.2004  0.687
2003 Ward P, Elias P, Linden RM. Rescue of the adeno-associated virus genome from a plasmid vector: evidence for rescue by replication. Journal of Virology. 77: 11480-90. PMID 14557633 DOI: 10.1128/Jvi.77.21.11480-11490.2003  0.509
2003 James JA, Escalante CR, Yoon-Robarts M, Edwards TA, Linden RM, Aggarwal AK. Crystal structure of the SF3 helicase from adeno-associated virus type 2. Structure (London, England : 1993). 11: 1025-35. PMID 12906833 DOI: 10.1016/S0969-2126(03)00152-7  0.429
2003 Yoon-Robarts M, Linden RM. Identification of active site residues of the adeno-associated virus type 2 Rep endonuclease. The Journal of Biological Chemistry. 278: 4912-8. PMID 12480938 DOI: 10.1074/Jbc.M209750200  0.403
2001 Ward P, Falkenberg M, Elias P, Weitzman M, Linden RM. Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system. Journal of Virology. 75: 10250-8. PMID 11581393 DOI: 10.1128/Jvi.75.21.10250-10258.2001  0.473
2001 Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, Linden RM, Moullier P, Salvetti A. Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences. Journal of Virology. 75: 9991-4. PMID 11559833 DOI: 10.1128/Jvi.75.20.9991-9994.2001  0.456
2001 Yoon M, Smith DH, Ward P, Medrano FJ, Aggarwal AK, Linden RM. Amino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro. Journal of Virology. 75: 3230-9. PMID 11238849 DOI: 10.1128/Jvi.75.7.3230-3239.2001  0.502
2000 Linden RM, Berns KI. Molecular biology of adeno-associated viruses. Contributions to Microbiology. 4: 68-84. PMID 10941571 DOI: 10.1159/000060327  0.555
2000 Dutheil N, Shi F, Dupressoir T, Linden RM. Adeno-associated virus site-specifically integrates into a muscle-specific DNA region. Proceedings of the National Academy of Sciences of the United States of America. 97: 4862-6. PMID 10758163 DOI: 10.1073/Pnas.080079397  0.478
2000 Ward P, Linden RM. A role for single-stranded templates in cell-free adeno-associated virus DNA replication. Journal of Virology. 74: 744-54. PMID 10623736 DOI: 10.1128/Jvi.74.2.744-754.2000  0.385
1999 Smith DH, Ward P, Linden RM. Comparative characterization of rep proteins from the helper-dependent adeno-associated virus type 2 and the autonomous goose parvovirus. Journal of Virology. 73: 2930-7. PMID 10074142 DOI: 10.1128/Jvi.73.4.2930-2937.1999  0.493
1997 Linden RM, Berns KI. Site-specific integration by adeno-associated virus: a basis for a potential gene therapy vector. Gene Therapy. 4: 4-5. PMID 9068788 DOI: 10.1038/Sj.Gt.3300357  0.631
1996 Linden RM, Ward P, Giraud C, Winocour E, Berns KI. Site-specific integration by adeno-associated virus. Proceedings of the National Academy of Sciences of the United States of America. 93: 11288-94. PMID 8876128 DOI: 10.1073/pnas.93.21.11288  0.679
1996 Linden RM, Winocour E, Berns KI. The recombination signals for adeno-associated virus site-specific integration. Proceedings of the National Academy of Sciences of the United States of America. 93: 7966-72. PMID 8755586 DOI: 10.1073/Pnas.93.15.7966  0.648
1995 Berns KI, Linden RM. The cryptic life style of adeno-associated virus. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 17: 237-45. PMID 7748178 DOI: 10.1002/Bies.950170310  0.649
1992 Kotin RM, Linden RM, Berns KI. Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination. The Embo Journal. 11: 5071-8. PMID 1334463 DOI: 10.1002/J.1460-2075.1992.Tb05614.X  0.705
Low-probability matches (unlikely to be authored by this person)
2002 Linden RM. Gene therapy gets the Beauty treatment. Nature Biotechnology. 20: 987-8. PMID 12355113 DOI: 10.1038/Nbt1002-987  0.291
2017 Zarate-Perez F, Santosh V, Bardelli M, Agundez L, Linden RM, Henckaerts E, Escalante C. Determination of Adeno-associated Virus Rep DNA Binding Using Fluorescence Anisotropy Bio-Protocol. 7. DOI: 10.21769/bioprotoc.2194  0.286
2009 Clément N, Battaglioli G, Jensen RL, Schnepp BC, Johnson PR, St George K, Linden RM. Prevalence of human bocavirus in human tonsils and adenoids. Emerging Infectious Diseases. 15: 1149-50. PMID 19624951 DOI: 10.3201/Eid1507.090102  0.276
2016 Henckaerts E, Tordo J, Palomar N, Rahman J, Aldrin-Kirk P, Basche M, Bennett A, O'Leary C, Ali R, Agbandje-McKenna M, Bigger B, Rahim AA, Björklund T, Waddington S, Linden RM. 256. A Novel Rationally Designed AAV Capsid Yields a Potent Neurotropic Gene Therapy Vector Molecular Therapy. 24: S101. DOI: 10.1016/S1525-0016(16)33065-9  0.274
1999 Linden RM, Woo SL. AAVant-garde gene therapy. Nature Medicine. 5: 21-2. PMID 9883831 DOI: 10.1038/4698  0.269
2019 Rosenblad C, Li Q, Pioli EY, Dovero S, Antunes ASLM, Agúndez L, Bardelli M, Linden RM, Henckaerts E, Björklund A, Bezard E, Björklund T. Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease. Brain : a Journal of Neurology. PMID 31243443 DOI: 10.1093/Brain/Awz176  0.268
2010 Zeltner N, Kohlbrenner E, Clément N, Weber T, Linden RM. Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors. Gene Therapy. 17: 872-9. PMID 20336156 DOI: 10.1038/gt.2010.27  0.262
2008 Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature. 453: 524-8. PMID 18432194 DOI: 10.1038/Nature06894  0.259
2017 Zarate-Perez F, Santosh V, Bardelli M, Agundez L, Linden RM, Henckaerts E, Escalante CR. Determination of Adeno-associated Virus Rep DNA Binding Using Fluorescence Anisotropy. Bio-Protocol. 7. PMID 28612042  0.258
2021 Lani-Louzada R, Dias MS, Linden R, de Toledo Ribas V, Petrs-Silva H. Gene Therapy Strategies for Glaucomatous Neurodegeneration. Current Gene Therapy. PMID 33573569 DOI: 10.2174/1566523221666210126152000  0.227
2012 Ponfick M, Hacker S, Gdynia HJ, Linden R, Gränz M, Nowak DA. Meningoencephaloradiculomyelitis after tick-borne encephalitis virus infection: a case series. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 19: 776-82. PMID 22289138 DOI: 10.1111/j.1468-1331.2011.03651.x  0.218
2021 Victorino PH, Marra C, Iacobas DA, Iacobas S, Spray DC, Linden R, Adesse D, Petrs-Silva H. Retinal Genomic Fabric Remodeling after Optic Nerve Injury. Genes. 12. PMID 33799827 DOI: 10.3390/genes12030403  0.205
2014 Petrs-Silva H, Linden R. Advances in gene therapy technologies to treat retinitis pigmentosa. Clinical Ophthalmology (Auckland, N.Z.). 8: 127-36. PMID 24391438 DOI: 10.2147/Opth.S38041  0.203
2023 Silva De Castro I, Granato A, Mariante RM, Lima MA, Leite ACC, Espindola OM, Pise-Masison CA, Franchini G, Linden R, Echevarria-Lima J. HTLV-1 p12 modulates the levels of prion protein (PrP) in CD4 T cells. Frontiers in Microbiology. 14: 1175679. PMID 37637115 DOI: 10.3389/fmicb.2023.1175679  0.198
2000 Chiarini LB, Freitas FG, Petrs-Silva H, Linden R. Evidence that the bifunctional redox factor / AP endonuclease Ref-1 is an anti-apoptotic protein associated with differentiation in the developing retina. Cell Death and Differentiation. 7: 272-81. PMID 10745272 DOI: 10.1038/Sj.Cdd.4400639  0.183
2018 Guimarães RPM, Landeira BS, Coelho DM, Golbert DCF, Silveira MS, Linden R, de Melo Reis RA, Costa MR. Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2. Frontiers in Cellular Neuroscience. 12: 410. PMID 30483060 DOI: 10.3389/Fncel.2018.00410  0.177
2013 da Silva BS, Rovaris DL, Bonotto RM, Meyer JB, Grohe RE, Perassolo MS, Palazzo Rde P, Maluf SW, Linden R, de Andrade FM. The influence on DNA damage of glycaemic parameters, oral antidiabetic drugs and polymorphisms of genes involved in the DNA repair system. Mutagenesis. 28: 525-30. PMID 23793614 DOI: 10.1093/mutage/get029  0.174
1999 Linden R, Rehen SK, Chiarini LB. Apoptosis in developing retinal tissue. Progress in Retinal and Eye Research. 18: 133-65. PMID 9932281 DOI: 10.1016/S1350-9462(98)00020-2  0.171
2008 Borges HL, Linden R, Wang JY. DNA damage-induced cell death: lessons from the central nervous system. Cell Research. 18: 17-26. PMID 18087290 DOI: 10.1038/Cr.2007.110  0.17
2005 Lopes MH, Hajj GN, Muras AG, Mancini GL, Castro RM, Ribeiro KC, Brentani RR, Linden R, Martins VR. Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11330-9. PMID 16339028 DOI: 10.1523/Jneurosci.2313-05.2005  0.168
1992 Schilling B, Linden RM, Kupper U, Lerch K. Expression of Neurospora crassa laccase under the control of the copper-inducible metallothionein-promoter. Current Genetics. 22: 197-203. PMID 1388108 DOI: 10.1007/BF00351726  0.168
2007 Magdesian MH, Tonelli RR, Fessel MR, Silveira MS, Schumacher RI, Linden R, Colli W, Alves MJ. A conserved domain of the gp85/trans-sialidase family activates host cell extracellular signal-regulated kinase and facilitates Trypanosoma cruzi infection. Experimental Cell Research. 313: 210-8. PMID 17101128 DOI: 10.1016/J.Yexcr.2006.10.008  0.167
2019 Rocha-Martins M, de Toledo BC, Santos-França PL, Oliveira-Valença VM, Vieira-Vieira CH, Matos-Rodrigues GE, Linden R, Norden C, Martins RAP, Silveira MS. genesis of retinal ganglion cells by targeted expression of . Development (Cambridge, England). 146. PMID 31405994 DOI: 10.1242/Dev.176586  0.166
2023 Garcia ALH, de Souza MR, Picinini J, Soares S, Rohr P, Linden R, Schneider A, Freitas MPM, Ely HC, Bobermin LD, Dos Santos AQ, Dalberto D, da Silva J. Unraveling gene expression and genetic instability in dental fluorosis: Investigating the impact of chronic fluoride exposure. The Science of the Total Environment. 906: 167393. PMID 37769727 DOI: 10.1016/j.scitotenv.2023.167393  0.163
2014 Linden R, Matte U. A snapshot of gene therapy in Latin America. Genetics and Molecular Biology. 37: 294-8. PMID 24764763 DOI: 10.1590/S1415-47572014000200015  0.163
2015 Musayev FN, Zarate-Perez F, Bardelli M, Bishop C, Saniev EF, Linden RM, Henckaerts E, Escalante CR. Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation. Biochemistry. 54: 5907-19. PMID 26314310 DOI: 10.1021/acs.biochem.5b00610  0.158
2012 Ribas VT, Gonçalves BS, Linden R, Chiarini LB. Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. Plos One. 7: e34483. PMID 22496813 DOI: 10.1371/Journal.Pone.0034483  0.154
2017 Linden R. The Biological Function of the Prion Protein: A Cell Surface Scaffold of Signaling Modules. Frontiers in Molecular Neuroscience. 10: 77. PMID 28373833 DOI: 10.3389/Fnmol.2017.00077  0.154
2007 Erlich RB, Kahn SA, Lima FR, Muras AG, Martins RA, Linden R, Chiarini LB, Martins VR, Moura Neto V. STI1 promotes glioma proliferation through MAPK and PI3K pathways. Glia. 55: 1690-8. PMID 17886292 DOI: 10.1002/Glia.20579  0.151
2007 Lobo DS, Pereira IB, Fragel-Madeira L, Medeiros LN, Cabral LM, Faria J, Bellio M, Campos RC, Linden R, Kurtenbach E. Antifungal Pisum sativum defensin 1 interacts with Neurospora crassa cyclin F related to the cell cycle. Biochemistry. 46: 987-96. PMID 17240982 DOI: 10.1021/Bi061441J  0.149
1999 Linden R, Chiarini LB. Nuclear exclusion of transcription factors associated with apoptosis in developing nervous tissue. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 32: 813-20. PMID 10454738 DOI: 10.1590/S0100-879X1999000700003  0.149
1996 Linden R, Rehen SK, Chiarini LB, Nakatani M, Rocha M, Campos CB, Borges HL, Varella MH, Freitas FG, Correa DF, Guimarães CA. Death in a dish: controls of apoptosis within the developing retinal tissue. Revista Brasileira De Biologia. 56: 89-103. PMID 9394492  0.148
2004 Petrs-Silva H, de Freitas FG, Linden R, Chiarini LB. Early nuclear exclusion of the transcription factor max is associated with retinal ganglion cell death independent of caspase activity. Journal of Cellular Physiology. 198: 179-87. PMID 14603520 DOI: 10.1002/Jcp.10404  0.147
1999 Rehen SK, Neves DD, Fragel-Madeira L, Britto LR, Linden R. Selective sensitivity of early postmitotic retinal cells to apoptosis induced by inhibition of protein synthesis. The European Journal of Neuroscience. 11: 4349-56. PMID 10594661 DOI: 10.1046/J.1460-9568.1999.00868.X  0.146
2002 Zanata SM, Lopes MH, Mercadante AF, Hajj GN, Chiarini LB, Nomizo R, Freitas AR, Cabral AL, Lee KS, Juliano MA, de Oliveira E, Jachieri SG, Burlingame A, Huang L, Linden R, et al. Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. The Embo Journal. 21: 3307-16. PMID 12093732 DOI: 10.1093/Emboj/Cdf325  0.145
1993 de Araujo EG, Linden R. Trophic factors produced by retinal cells increase the survival of retinal ganglion cells in vitro. The European Journal of Neuroscience. 5: 1181-8. PMID 8281322 DOI: 10.1111/J.1460-9568.1993.Tb00972.X  0.144
2009 Martini SV, Fagundes SS, Schmidt AC, Avila M, Ornellas DS, Ribas VT, Petrs-Silva H, Linden R, Faffe DS, Guggino SE, Rocco PR, Zin WA, Morales MM. Does the use of recombinant AAV5 in pulmonary gene therapy lead to lung damage? Respiratory Physiology & Neurobiology. 168: 203-9. PMID 19573627 DOI: 10.1016/J.Resp.2009.06.016  0.144
2010 Njaine B, Martins RA, Santiago MF, Linden R, Silveira MS. Pituitary adenylyl cyclase-activating polypeptide controls the proliferation of retinal progenitor cells through downregulation of cyclin D1. The European Journal of Neuroscience. 32: 311-21. PMID 20646049 DOI: 10.1111/J.1460-9568.2010.07286.X  0.143
1994 Rehen SK, Linden R. Apoptosis in the developing retina: paradoxical effects of protein synthesis inhibition. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 27: 1647-51. PMID 7874031  0.143
2014 Njaine B, Rocha-Martins M, Vieira-Vieira CH, De-Melo LD, Linden R, Braas K, May V, Martins RA, Silveira MS. Pleiotropic functions of pituitary adenylyl cyclase-activating polypeptide on retinal ontogenesis: involvement of KLF4 in the control of progenitor cell proliferation. Journal of Molecular Neuroscience : Mn. 54: 430-42. PMID 24715357 DOI: 10.1007/S12031-014-0299-2  0.143
1997 Ary-Pires R, Nakatani M, Rehen SK, Linden R. Developmentally regulated release of intraretinal neurotrophic factors in vitro. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 15: 239-55. PMID 9178042 DOI: 10.1016/S0736-5748(96)00087-1  0.142
2006 Martins RA, Linden R, Dyer MA. Glutamate regulates retinal progenitors cells proliferation during development. The European Journal of Neuroscience. 24: 969-80. PMID 16925590 DOI: 10.1111/J.1460-9568.2006.04966.X  0.142
2011 Ribas VT, Arruda-Carvalho M, Linden R, Chiarini LB. Early c-Jun N-terminal kinase-dependent phosphorylation of activating transcription factor-2 is associated with degeneration of retinal ganglion cells. Neuroscience. 180: 64-74. PMID 21300140 DOI: 10.1016/J.Neuroscience.2011.01.059  0.141
2010 Martins VR, Beraldo FH, Hajj GN, Lopes MH, Lee KS, Prado MA, Linden R. Prion protein: orchestrating neurotrophic activities. Current Issues in Molecular Biology. 12: 63-86. PMID 19767651  0.141
2006 Campos CB, Bédard PA, Linden R. Requirement of p38 stress-activated MAP kinase for cell death in the developing retina depends on the stage of cell differentiation. Neurochemistry International. 49: 494-9. PMID 16782232 DOI: 10.1016/J.Neuint.2006.03.011  0.14
2008 Carneiro AC, Fragel-Madeira L, Silva-Neto MA, Linden R. A role for CK2 upon interkinetic nuclear migration in the cell cycle of retinal progenitor cells. Developmental Neurobiology. 68: 620-31. PMID 18278803 DOI: 10.1002/Dneu.20613  0.138
2003 Chiarini LB, Leal-Ferreira ML, de Freitas FG, Linden R. Changing sensitivity to cell death during development of retinal photoreceptors. Journal of Neuroscience Research. 74: 875-83. PMID 14648592 DOI: 10.1002/Jnr.10739  0.138
2000 Chiarini LB, Linden R. Tissue biology of apoptosis. Ref-1 and cell differentiation in the developing retina. Annals of the New York Academy of Sciences. 926: 64-78. PMID 11193042 DOI: 10.1111/J.1749-6632.2000.Tb05599.X  0.137
2002 Silveira MS, Costa MR, Bozza M, Linden R. Pituitary adenylyl cyclase-activating polypeptide prevents induced cell death in retinal tissue through activation of cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 277: 16075-80. PMID 11847214 DOI: 10.1074/Jbc.M110106200  0.137
2002 Campos CB, Bédard PA, Linden R. Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina. Neuroscience. 112: 583-91. PMID 12074900 DOI: 10.1016/S0306-4522(02)00096-9  0.137
2005 Linden R, Martins RA, Silveira MS. Control of programmed cell death by neurotransmitters and neuropeptides in the developing mammalian retina. Progress in Retinal and Eye Research. 24: 457-91. PMID 15845345 DOI: 10.1016/J.Preteyeres.2004.10.001  0.135
2015 Pinheiro LP, Linden R, Mariante RM. Activation and function of murine primary microglia in the absence of the prion protein. Journal of Neuroimmunology. 286: 25-32. PMID 26298321 DOI: 10.1016/J.Jneuroim.2015.07.002  0.135
2003 Lee KS, Linden R, Prado MA, Brentani RR, Martins VR. Towards cellular receptors for prions. Reviews in Medical Virology. 13: 399-408. PMID 14625887 DOI: 10.1002/Rmv.408  0.135
2004 Prado MA, Alves-Silva J, Magalhães AC, Prado VF, Linden R, Martins VR, Brentani RR. PrPc on the road: trafficking of the cellular prion protein. Journal of Neurochemistry. 88: 769-81. PMID 14756798 DOI: 10.1046/J.1471-4159.2003.02199.X  0.134
1993 Bosco A, Carri NG, Linden R. Neuritogenesis of retinal ganglion cells is differentially promoted by target extract. Brain Research. 632: 303-7. PMID 8149235 DOI: 10.1016/0006-8993(93)91165-O  0.133
2002 Martins VR, Linden R, Prado MA, Walz R, Sakamoto AC, Izquierdo I, Brentani RR. Cellular prion protein: on the road for functions. Febs Letters. 512: 25-8. PMID 11852045 DOI: 10.1016/S0014-5793(02)02291-3  0.133
2003 Campos CB, Bédard PA, Linden R. Selective involvement of the PI3K/PKB/bad pathway in retinal cell death. Journal of Neurobiology. 56: 171-7. PMID 12838582 DOI: 10.1002/Neu.10234  0.132
2008 Linden R, Martins VR, Prado MA, Cammarota M, Izquierdo I, Brentani RR. Physiology of the prion protein. Physiological Reviews. 88: 673-728. PMID 18391177 DOI: 10.1152/Physrev.00007.2007  0.132
1990 Serfaty CA, Reese BE, Linden R. Cell death and interocular interactions among retinofugal axons: lack of binocularly matched specificity. Brain Research. Developmental Brain Research. 56: 198-204. PMID 1702041 DOI: 10.1016/0165-3806(90)90082-A  0.132
2007 De Almeida Dias F, Souza Dos Santos AL, Ferreira-Pereira A, Romeiro A, Teixeira Zimmermann L, Cunha do Nascimento MT, Correa Atella G, Saraiva EM, Linden R, Hampshire Lopes A. Development of a ligand blot assay using biotinylated live cells. Journal of Biomolecular Screening. 12: 1006-10. PMID 17942794 DOI: 10.1177/1087057107307146  0.132
1996 Rehen SK, Varella MH, Freitas FG, Moraes MO, Linden R. Contrasting effects of protein synthesis inhibition and of cyclic AMP on apoptosis in the developing retina. Development (Cambridge, England). 122: 1439-48. PMID 8625832  0.132
2014 Ali SR, Fong JJ, Carlin AF, Busch TD, Linden R, Angata T, Areschoug T, Parast M, Varki N, Murray J, Nizet V, Varki A. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. The Journal of Experimental Medicine. 211: 1231-42. PMID 24799499 DOI: 10.1084/Jem.20131853  0.131
2003 Cusato K, Bosco A, Rozental R, Guimarães CA, Reese BE, Linden R, Spray DC. Gap junctions mediate bystander cell death in developing retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6413-22. PMID 12878681 DOI: 10.1523/Jneurosci.23-16-06413.2003  0.13
2002 Chiarini LB, de Freitas FG, Leal-Ferreira ML, Tolkovsky A, Linden R. Cytoplasmic c-Jun N-terminal immunoreactivity: a hallmark of retinal apoptosis. Cellular and Molecular Neurobiology. 22: 711-26. PMID 12585690 DOI: 10.1023/A:1021857007976  0.129
2002 Rehen SK, Cid M, Fragel-Madeira L, Linden R. Differential effects of cyclin-dependent kinase blockers upon cell death in the developing retina. Brain Research. 947: 78-83. PMID 12144855 DOI: 10.1016/S0006-8993(02)02909-8  0.129
2007 Arruda-Carvalho M, Njaine B, Silveira MS, Linden R, Chiarini LB. Hop/STI1 modulates retinal proliferation and cell death independent of PrPC. Biochemical and Biophysical Research Communications. 361: 474-80. PMID 17651690 DOI: 10.1016/J.Bbrc.2007.07.038  0.128
2002 Freire E, Gomes FC, Linden R, Neto VM, Coelho-Sampaio T. Structure of laminin substrate modulates cellular signaling for neuritogenesis. Journal of Cell Science. 115: 4867-76. PMID 12432074 DOI: 10.1242/Jcs.00173  0.128
1993 Rehen SK, Ary-Pires R, Linden R. Intraretinal neurotrophic activity prevents the degeneration of ganglion cells in retinal explants. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 26: 955-9. PMID 7905330  0.128
2002 Cusato K, Bosco A, Linden R, Reese BE. Cell death in the inner nuclear layer of the retina is modulated by BDNF. Brain Research. Developmental Brain Research. 139: 325-30. PMID 12480149 DOI: 10.1016/S0165-3806(02)00570-9  0.127
2001 Neves DD, Rehen SK, Linden R. Differentiation-dependent sensitivity to cell death induced in the developing retina by inhibitors of the ubiquitin-proteasome proteolytic pathway. The European Journal of Neuroscience. 13: 1938-44. PMID 11403687 DOI: 10.1046/J.0953-816X.2001.01571.X  0.127
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Linden R, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.127
2005 de Almeida CJ, Chiarini LB, da Silva JP, E Silva PM, Martins MA, Linden R. The cellular prion protein modulates phagocytosis and inflammatory response. Journal of Leukocyte Biology. 77: 238-46. PMID 15539455 DOI: 10.1189/Jlb.1103531  0.126
1992 Ary-Pires R, Rehen SK, Linden R. Evidence for a developmentally regulated neurotrophic activity from chick retina affecting the survival of retinal ganglion cells from newborn rats. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 25: 845-8. PMID 1342620  0.126
2005 de Almeida CJ, Linden R. Phagocytosis of apoptotic cells: a matter of balance. Cellular and Molecular Life Sciences : Cmls. 62: 1532-46. PMID 15905967 DOI: 10.1007/S00018-005-4511-Y  0.125
2008 Caetano FA, Lopes MH, Hajj GN, Machado CF, Pinto Arantes C, Magalhães AC, Vieira Mde P, Américo TA, Massensini AR, Priola SA, Vorberg I, Gomez MV, Linden R, Prado VF, Martins VR, et al. Endocytosis of prion protein is required for ERK1/2 signaling induced by stress-inducible protein 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6691-702. PMID 18579743 DOI: 10.1523/Jneurosci.1701-08.2008  0.125
1986 Linden R, Cavalcante LA, Barradas PC. Mononuclear phagocytes in the retina of developing rats. Histochemistry. 85: 335-9. PMID 3759506 DOI: 10.1007/Bf00493486  0.124
2004 Borges HL, Chao C, Xu Y, Linden R, Wang JY. Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53. Cell Death and Differentiation. 11: 494-502. PMID 14752509 DOI: 10.1038/Sj.Cdd.4401366  0.124
1990 de Araujo EG, Linden R. Survival of retinal ganglion cells in vitro: the effect of conditioned medium from retinal cell aggregates. Brazilian Journal of Medical and Biological Research. 23: 743-746. PMID 2101104  0.124
2000 Linden R. The anti-death league: associative control of apoptosis in developing retinal tissue. Brain Research. Brain Research Reviews. 32: 146-58. PMID 10751664 DOI: 10.1016/S0165-0173(99)00073-9  0.122
2021 Hollmann G, da Silva PGC, Linden R, Allodi S. Cell proliferation in the central nervous system of an adult semiterrestrial crab. Cell and Tissue Research. PMID 33599819 DOI: 10.1007/s00441-021-03413-y  0.122
1982 Perry VH, Linden R. Evidence for dendritic competition in the developing retina. Nature. 297: 683-5. PMID 7088156 DOI: 10.1038/297683A0  0.122
2009 Romano SA, Cordeiro Y, Lima LM, Lopes MH, Silva JL, Foguel D, Linden R. Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4308-16. PMID 19703931 DOI: 10.1096/Fj.09-138974  0.122
2008 Lassance RM, Pássaro CP, Martini SV, Castiglione RC, Gutierrez TM, Abreu SC, Antunes MA, Xisto DG, Cebotaru L, Petrs-Silva H, Zin WA, Guggino WB, Linden R, Rocco PR, Morales MM. Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function? Respiratory Physiology & Neurobiology. 160: 91-8. PMID 17950048 DOI: 10.1016/J.Resp.2007.09.002  0.122
2003 Erlich RB, Werneck CC, Mourão PA, Linden R. Major glycosaminoglycan species in the developing retina: synthesis, tissue distribution and effects upon cell death. Experimental Eye Research. 77: 157-65. PMID 12873445 DOI: 10.1016/S0014-4835(03)00129-5  0.122
1985 Linden R, Pinto LH. Developmental genetics of the retina: evidence that the pearl mutation in the mouse affects the time course of natural cell death in the ganglion cell layer. Experimental Brain Research. 60: 79-86. PMID 4043284 DOI: 10.1007/BF00237021  0.121
2001 Guimarães C, Assreuy J, Linden R. Paracrine neuroprotective effect of nitric oxide in the developing retina. Journal of Neurochemistry. 76: 1233-41. PMID 11181842 DOI: 10.1046/J.1471-4159.2001.00126.X  0.121
2011 Fragel-Madeira L, Meletti T, Mariante RM, Monteiro RQ, Einicker-Lamas M, Bernardo RR, Lopes AH, Linden R. Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition. Plos One. 6: e16058. PMID 21298035 DOI: 10.1371/Journal.Pone.0016058  0.12
1999 Borges HL, Linden R. Gamma irradiation leads to two waves of apoptosis in distinct cell populations of the retina of newborn rats. Journal of Cell Science. 112: 4315-24. PMID 10564649  0.119
1996 Piñón LG, Linden R. Target and afferents interact to control developmental cell death in the mesencephalic parabigeminal nucleus of the rat. Journal of Neuroscience Research. 45: 174-82. PMID 8843034 DOI: 10.1002/(Sici)1097-4547(19960715)45:2<174::Aid-Jnr9>3.0.Co;2-7  0.118
1997 Varella MH, Correa DF, Campos CB, Chiarini LB, Linden R. Protein kinases selectively modulate apoptosis in the developing retina in vitro. Neurochemistry International. 31: 217-27. PMID 9220454 DOI: 10.1016/S0197-0186(96)00151-9  0.118
1999 Bosco A, Linden R. BDNF and NT-4 differentially modulate neurite outgrowth in developing retinal ganglion cells. Journal of Neuroscience Research. 57: 759-69. PMID 10467247 DOI: 10.1002/(Sici)1097-4547(19990915)57:6<759::Aid-Jnr1>3.0.Co;2-Y  0.117
2008 Petrs-Silva H, Chiarini LB, Linden R. Nuclear proteasomal degradation and cytoplasmic retention underlie early nuclear exclusion of transcription factor Max upon axon damage. Experimental Neurology. 213: 202-9. PMID 18601921 DOI: 10.1016/J.Expneurol.2008.06.001  0.117
2013 Hajj GN, Arantes CP, Dias MV, Roffé M, Costa-Silva B, Lopes MH, Porto-Carreiro I, Rabachini T, Lima FR, Beraldo FH, Prado MA, Prado MM, Linden R, Martins VR. The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles. Cellular and Molecular Life Sciences : Cmls. 70: 3211-27. PMID 23543276 DOI: 10.1007/S00018-013-1328-Y  0.117
2001 Schmidt SL, Vitral RW, Linden R. Effects of prenatal ionizing irradiation on the development of the ganglion cell layer of the mouse retina. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 469-73. PMID 11378306 DOI: 10.1016/S0736-5748(00)00068-X  0.116
2003 Guimarães CA, Benchimol M, Amarante-Mendes GP, Linden R. Alternative programs of cell death in developing retinal tissue. The Journal of Biological Chemistry. 278: 41938-46. PMID 12917395 DOI: 10.1074/Jbc.M306547200  0.116
2007 Americo TA, Chiarini LB, Linden R. Signaling induced by hop/STI-1 depends on endocytosis. Biochemical and Biophysical Research Communications. 358: 620-5. PMID 17498662 DOI: 10.1016/J.Bbrc.2007.04.202  0.115
2011 Trindade P, Antonioli-Santos R, Teixeira AC, Lanzillotta-Mattos B, Melibeu AC, Campello-Costa P, Linden R, Serfaty CA. Evidence for a role of calcineurin in the development of retinocollicular fine topography. Neuroscience Letters. 487: 47-52. PMID 20920550 DOI: 10.1016/J.Neulet.2010.09.071  0.115
2022 Lani-Louzada R, Abreu CA, Araújo VG, Dias MS, Petrs-Silva H, Linden R. Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents. Journal of Visualized Experiments : Jove. PMID 35253788 DOI: 10.3791/63442  0.114
2006 Villegas SN, Njaine B, Linden R, Carri NG. Glial-derived neurotrophic factor (GDNF) prevents ethanol (EtOH) induced B92 glial cell death by both PI3K/AKT and MEK/ERK signaling pathways. Brain Research Bulletin. 71: 116-26. PMID 17113937 DOI: 10.1016/J.Brainresbull.2006.08.014  0.113
2006 Silveira MS, Linden R. Neuroprotection by cAMP: Another brick in the wall. Advances in Experimental Medicine and Biology. 557: 164-76. PMID 16955710 DOI: 10.1007/0-387-30128-3_10  0.113
1990 Serfaty CA, Linden R. Development of abnormal lamination and binocular segregation of retinal afferents onto the rat superior colliculus. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 23: 663-6. PMID 2101090  0.113
2013 Luz AJ, Poeta J, Linden R, Antunes MV, Caminha LI, Callegari-Jacques SM, Sprinz E. Association between atazanavir plasma levels and renal function in HIV-positive individuals on antiretroviral therapy with undetectable viral load. International Journal of Antimicrobial Agents. 41: 497-8. PMID 23453620 DOI: 10.1016/j.ijantimicag.2013.01.013  0.112
2000 de Ary-Pires R, Linden R. Laminin modulates neuritogenesis of developing rat retinal ganglion cells through a protein kinase C-dependent pathway. Journal of Neuroscience Research. 60: 291-301. PMID 10797531 DOI: 10.1002/(Sici)1097-4547(20000501)60:3<291::Aid-Jnr3>3.0.Co;2-Y  0.112
1987 Linden R. Displaced ganglion cells in the retina of the rat. The Journal of Comparative Neurology. 258: 138-43. PMID 3571534 DOI: 10.1002/Cne.902580111  0.111
2019 Lani R, Dias MS, Abreu CA, Araújo VG, Gonçalo T, Nascimento-Dos-Santos G, Dantas AM, Allodi S, Fiorani M, Petrs-Silva H, Linden R. A subacute model of glaucoma based on limbal plexus cautery in pigmented rats. Scientific Reports. 9: 16286. PMID 31705136 DOI: 10.1038/S41598-019-52500-2  0.111
2010 Sternberg C, Benchimol M, Linden R. Caspase dependence of the death of neonatal retinal ganglion cells induced by axon damage and induction of autophagy as a survival mechanism. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 43: 950-6. PMID 20802972 DOI: 10.1590/S0100-879X2010007500082  0.11
1990 Williams MA, Piñon LG, Linden R, Pinto LH. The pearl mutation accelerates the schedule of natural cell death in the early postnatal retina. Experimental Brain Research. 82: 393-400. PMID 2286240 DOI: 10.1007/BF00231258  0.11
2005 Martins RA, Silveira MS, Curado MR, Police AI, Linden R. NMDA receptor activation modulates programmed cell death during early post-natal retinal development: a BDNF-dependent mechanism. Journal of Neurochemistry. 95: 244-53. PMID 16181428 DOI: 10.1111/J.1471-4159.2005.03360.X  0.108
1985 Linden R, Serfaty CA. Evidence for differential effects of terminal and dendritic competition upon developmental neuronal death in the retina. Neuroscience. 15: 853-68. PMID 4069356 DOI: 10.1016/0306-4522(85)90083-1  0.108
2010 Adão-Novaes J, de Cássia Belem Guterrres C, Linden R, Sholl-Franco A. Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1. Neurochemistry International. 57: 128-35. PMID 20466029 DOI: 10.1016/J.Neuint.2010.04.021  0.108
2002 Chiarini LB, Freitas AR, Zanata SM, Brentani RR, Martins VR, Linden R. Cellular prion protein transduces neuroprotective signals. The Embo Journal. 21: 3317-26. PMID 12093733 DOI: 10.1093/Emboj/Cdf324  0.107
2021 Nascimento-Dos-Santos G, de-Souza-Ferreira E, Linden R, Galina A, Petrs-Silva H. Mitotherapy: Unraveling a Promising Treatment for Disorders of the Central Nervous System and Other Systemic Conditions. Cells. 10. PMID 34359994 DOI: 10.3390/cells10071827  0.106
2011 Beraldo FH, Arantes CP, Santos TG, Machado CF, Roffe M, Hajj GN, Lee KS, Magalhães AC, Caetano FA, Mancini GL, Lopes MH, Américo TA, Magdesian MH, Ferguson SS, Linden R, et al. Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 265-79. PMID 20876210 DOI: 10.1096/Fj.10-161653  0.106
1983 Perry VH, Henderson Z, Linden R. Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat. The Journal of Comparative Neurology. 219: 356-68. PMID 6619343 DOI: 10.1002/Cne.902190309  0.105
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Linden R, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.105
1994 Linden R. The survival of developing neurons: a review of afferent control. Neuroscience. 58: 671-82. PMID 8190251 DOI: 10.1016/0306-4522(94)90447-2  0.104
2012 Linden R, Cordeiro Y, Lima LM. Allosteric function and dysfunction of the prion protein. Cellular and Molecular Life Sciences : Cmls. 69: 1105-24. PMID 21984610 DOI: 10.1007/S00018-011-0847-7  0.104
2020 Nascimento-Dos-Santos G, de-Souza-Ferreira E, Lani R, de Faria CC, Araujo VG, Teixeira-Pinheiro LC, de Souza Vasconcelos T, Leandro TG, Santiago MF, Linden R, Galina A, Petrs-Silva H. Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165686. PMID 31953215 DOI: 10.1016/J.Bbadis.2020.165686  0.103
1991 Nakatani M, Linden R. Axon orientation and axo-dendritic polarity of retinal ganglion cells during postnatal development in the rat. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 24: 937-41. PMID 1797289  0.103
2001 Schmidt SL, Vitral RW, Linden R. Depletion of cortical target induced by prenatal ionizing irradiation: effects on the lateral geniculate nucleus and on the retinofugal pathways. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 475-83. PMID 11378307 DOI: 10.1016/S0736-5748(00)00067-8  0.103
2013 Luz AJ, Poeta J, Linden R, Antunes MV, Caminha LI, Sprinz E. Related factors to atazanavir plasma levels in a cohort of HIV positive individuals with undetectable viral load. The Brazilian Journal of Infectious Diseases : An Official Publication of the Brazilian Society of Infectious Diseases. 17: 657-60. PMID 23933406 DOI: 10.1016/j.bjid.2013.04.002  0.102
2018 Barbosa E, Dos Santos ALA, Peteffi GP, Schneider A, Müller D, Rovaris D, Bau CHD, Linden R, Antunes MV, Charão MF. Increase of global DNA methylation patterns in beauty salon workers exposed to low levels of formaldehyde. Environmental Science and Pollution Research International. PMID 30421373 DOI: 10.1007/s11356-018-3674-7  0.102
1985 Lent R, Linden R, Cavalcante LA. Transient populations of presumptive macrophages in the brain of the developing hamster, as indicated by endocytosis of blood-borne horseradish peroxidase. Neuroscience. 15: 1203-15. PMID 4047400 DOI: 10.1016/0306-4522(85)90263-5  0.102
2012 Feksa LR, Oliveira E, Trombini T, Luchese M, Bisi S, Linden R, Berlese DB, Rojas DB, Andrade RB, Schuck PF, Lacerda LM, Wajner M, Wannmacher CM, Emanuelli T. Pyruvate kinase activity and δ-aminolevulinic acid dehydratase activity as biomarkers of toxicity in workers exposed to lead. Archives of Environmental Contamination and Toxicology. 63: 453-60. PMID 22864587 DOI: 10.1007/s00244-012-9786-z  0.101
1990 Piñon LG, Linden R. Interactive effects of deafferentation and target removal on cell death in the parabigeminal nucleus of developing rats. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 23: 659-62. PMID 2101089  0.1
2016 Beckman D, Linden R. A roadmap for investigating the role of the prion protein in depression associated with neurodegenerative disease. Prion. 0. PMID 27057694 DOI: 10.1080/19336896.2016.1152437  0.1
1982 Linden R, Perry VH. Ganglion cell death within the developing retina: a regulatory role for retinal dendrites? Neuroscience. 7: 2813-27. PMID 7155355 DOI: 10.1016/0306-4522(82)90104-X  0.099
2018 da Silva Chagas L, Trindade P, Gomes ALT, Mendonça HR, Campello-Costa P, da Cunha Faria Melibeu A, Linden R, Serfaty CA. Rapid plasticity of intact axons following a lesion to the visual pathways during early brain development is triggered by microglial activation. Experimental Neurology. PMID 30312606 DOI: 10.1016/J.Expneurol.2018.10.002  0.099
2006 Silva KL, Vasconcellos DV, Castro ED, Coelho AM, Linden R, Maia RC. Apoptotic effect of fludarabine is independent of expression of IAPs in B-cell chronic lymphocytic leukemia. Apoptosis : An International Journal On Programmed Cell Death. 11: 277-85. PMID 16502265 DOI: 10.1007/s10495-006-3560-5  0.099
2008 da Fonseca CO, Linden R, Futuro D, Gattass CR, Quirico-Santos T. Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol. Archivum Immunologiae Et Therapiae Experimentalis. 56: 267-76. PMID 18726148 DOI: 10.1007/S00005-008-0027-0  0.099
2005 Wasilewska-Sampaio AP, Silveira MS, Holub O, Goecking R, Gomes FC, Neto VM, Linden R, Ferreira ST, De Felice FG. Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1627-36. PMID 16195371 DOI: 10.1096/Fj.05-3812Com  0.098
1993 Linden R. Dendritic competition in the developing retina: ganglion cell density gradients and laterally displaced dendrites. Visual Neuroscience. 10: 313-24. PMID 8485094 DOI: 10.1017/S0952523800003710  0.097
2010 Sholl-Franco A, Fragel-Madeira L, Macama Ada C, Linden R, Ventura AL. ATP controls cell cycle and induces proliferation in the mouse developing retina. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 28: 63-73. PMID 19799993 DOI: 10.1016/J.Ijdevneu.2009.09.004  0.097
2000 Guimarães CA, Linden R. Chloramphenicol induces apoptosis in the developing brain. Neuropharmacology. 39: 1673-9. PMID 10854912 DOI: 10.1016/S0028-3908(99)00246-4  0.096
2016 Carneiro MV, Americo TA, Guimarães MZ, Linden R. The prion protein selectively binds to and modulates the content of purinergic receptor P2X4R. Biochemical and Biophysical Research Communications. PMID 26946358 DOI: 10.1016/J.Bbrc.2016.02.122  0.096
2004 Assunção Guimarães C, Linden R. Programmed cell deaths. Apoptosis and alternative deathstyles. European Journal of Biochemistry / Febs. 271: 1638-50. PMID 15096203 DOI: 10.1111/J.1432-1033.2004.04084.X  0.096
2019 Adão-Novaes J, Valverde RHF, Landemberger MC, Silveira MS, Simões-Pires EN, Lowe J, Linden R. Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice. Brain Research. 146550. PMID 31726043 DOI: 10.1016/J.Brainres.2019.146550  0.095
2012 Moro AM, Brucker N, Charão M, Bulcão R, Freitas F, Baierle M, Nascimento S, Valentini J, Cassini C, Salvador M, Linden R, Thiesen F, Buffon A, Moresco R, Garcia SC. Evaluation of genotoxicity and oxidative damage in painters exposed to low levels of toluene. Mutation Research. 746: 42-8. PMID 22405974 DOI: 10.1016/j.mrgentox.2012.02.007  0.094
2011 Marra C, Gomes Moret D, de Souza Corrêa A, Chagas da Silva F, Moraes P, Linden R, Sholl-Franco A. Protein kinases JAK and ERK mediate protective effect of interleukin-2 upon ganglion cells of the developing rat retina. Journal of Neuroimmunology. 233: 120-6. PMID 21262542 DOI: 10.1016/J.Jneuroim.2010.12.008  0.094
1987 Linden R, Esbérard CE. Displaced amacrine cells in the ganglion cell layer of the hamster retina. Vision Research. 27: 1071-6. PMID 3660661 DOI: 10.1016/0042-6989(87)90021-6  0.092
1983 Linden R, Perry VH. Massive retinotectal projection in rats. Brain Research. 272: 145-9. PMID 6616190 DOI: 10.1016/0006-8993(83)90371-2  0.092
2012 Mariante RM, Nóbrega A, Martins RA, Areal RB, Bellio M, Linden R. Neuroimmunoendocrine regulation of the prion protein in neutrophils. The Journal of Biological Chemistry. 287: 35506-15. PMID 22910907 DOI: 10.1074/Jbc.M112.394924  0.089
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Linden R, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.089
2002 Reis RA, Cabral da Silva MC, Loureiro dos Santos NE, Bampton E, Taylor JS, de Mello FG, Linden R. Sympathetic neuronal survival induced by retinal trophic factors. Journal of Neurobiology. 50: 13-23. PMID 11748629 DOI: 10.1002/Neu.10008  0.087
2003 Mariante RM, Guimarães CA, Linden R, Benchimol M. Hydrogen peroxide induces caspase activation and programmed cell death in the amitochondrial Tritrichomonas foetus. Histochemistry and Cell Biology. 120: 129-41. PMID 12844218 DOI: 10.1007/S00418-003-0548-X  0.087
2009 Adão-Novaes J, Guterres Cde C, da Silva AG, Campello-Costa P, Linden R, Sholl-Franco A. Interleukin-4 blocks thapsigargin-induced cell death in rat rod photoreceptors: involvement of cAMP/PKA pathway. Journal of Neuroscience Research. 87: 2167-74. PMID 19235892 DOI: 10.1002/Jnr.22026  0.087
2018 Hahn RZ, Antunes MV, Verza SG, Perassolo MS, Suyenaga ES, Schwartsmann G, Linden R. Pharmacokinetic and pharmacogenetic markers of irinotecan toxicity. Current Medicinal Chemistry. PMID 29932028 DOI: 10.2174/0929867325666180622141101  0.086
2022 Basso J, Schwartsmann G, Ibaldi MR, Schaefer VD, Pavei CC, Hahn RZ, Antunes MV, Linden R. Evaluation of UGT1A1 and CYP3A Genotyping and Single-Point Irinotecan and Metabolite Concentrations as Predictors of the Occurrence of Adverse Events in Cancer Treatment. Journal of Gastrointestinal Cancer. PMID 35710870 DOI: 10.1007/s12029-022-00840-0  0.085
2023 Chiarini LB, Petrs-Silva H, Linden R. Novel approaches to glaucomatous neurodegeneration, based on the integrated stress response. Molecular Therapy. Nucleic Acids. 33: 845-847. PMID 37662966 DOI: 10.1016/j.omtn.2023.08.022  0.084
1999 Varella MH, de Mello FG, Linden R. Evidence for an antiapoptotic role of dopamine in developing retinal tissue. Journal of Neurochemistry. 73: 485-92. PMID 10428043 DOI: 10.1046/J.1471-4159.1999.0730485.X  0.084
2005 Serfaty CA, Campello-Costa P, Linden R. Rapid and long-term plasticity in the neonatal and adult retinotectal pathways following a retinal lesion. Brain Research Bulletin. 66: 128-34. PMID 15982529 DOI: 10.1016/J.Brainresbull.2005.04.005  0.083
1994 Serfaty CA, Linden R. Development of abnormal lamination and binocular segregation in the retinotectal pathways of the rat. Brain Research. Developmental Brain Research. 82: 35-44. PMID 7531121 DOI: 10.1016/0165-3806(94)90146-5  0.082
2012 Antunes MV, Linden R, Santos TV, Wallemacq P, Haufroid V, Classen JF, Andreolla H, Costa N, Fontanive TO, Rosa DD. Endoxifen levels and its association with CYP2D6 genotype and phenotype: evaluation of a southern Brazilian population under tamoxifen pharmacotherapy. Therapeutic Drug Monitoring. 34: 422-31. PMID 22777153 DOI: 10.1097/FTD.0b013e318260b46e  0.082
2018 Andriguetti NB, Hahn RZ, Lizot LF, Raymundo S, Costa JL, da Cunha KF, Vilela RMM, Kluck HM, Schwartsmann G, Antunes MV, Linden R. Analytical and clinical validation of a dried blood spot assay for the determination of paclitaxel using high-performance liquid chromatography-tandem mass spectrometry. Clinical Biochemistry. PMID 29514052 DOI: 10.1016/j.clinbiochem.2018.02.020  0.082
2022 Krützmann ME, Martini RR, de Souza Guterres F, Kohlrausch R, Wagner SC, Mattevi VS, Torriani MS, Fogliatto LM, Linden R, Antunes MV. Volumetric dried blood microsampling for monitoring imatinib mesylate therapy: Method development and clinical application in patients with chronic myeloid leukemia. Journal of Pharmaceutical and Biomedical Analysis. 222: 115108. PMID 36279845 DOI: 10.1016/j.jpba.2022.115108  0.081
2011 Lindoso RS, Araujo DS, Adão-Novaes J, Mariante RM, Verdoorn KS, Fragel-Madeira L, Caruso-Neves C, Linden R, Vieyra A, Einicker-Lamas M. Paracrine interaction between bone marrow-derived stem cells and renal epithelial cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 267-78. PMID 21865734 DOI: 10.1159/000331739  0.081
2020 Tagliari CFDS, de Oliveira CN, Vogel GM, da Silva PB, Linden R, Lazzaretti RK, Notti RK, Sprinz E, Mattevi VS. Investigation of SIRT1 gene variants in HIV-associated lipodystrophy and metabolic syndrome. Genetics and Molecular Biology. 43: e20190142. PMID 32106282 DOI: 10.1590/1678-4685-GMB-2019-0142  0.077
2021 Delahaye L, Veenhof H, Koch BCP, Alffenaar JC, Linden R, Stove C. Alternative Sampling Devices to Collect Dried Blood Microsamples: State-of-the-Art. Therapeutic Drug Monitoring. PMID 33470777 DOI: 10.1097/FTD.0000000000000864  0.076
2016 Hollmann G, Linden R, Giangrande A, Allodi S. Increased p53 and decreased p21 accompany apoptosis induced by ultraviolet radiation in the nervous system of a crustacean. Aquatic Toxicology (Amsterdam, Netherlands). 173: 1-8. PMID 26807499 DOI: 10.1016/J.Aquatox.2015.12.025  0.076
1990 Linden R. Control of neuronal survival by anomalous targets in the developing brain. The Journal of Comparative Neurology. 294: 594-606. PMID 2341627 DOI: 10.1002/Cne.902940407  0.075
2015 Peteffi GP, Basso da Silva L, Antunes MV, Wilhelm C, Valandro ET, Glaeser J, Kaefer D, Linden R. Evaluation of genotoxicity in workers exposed to low levels of formaldehyde in a furniture manufacturing facility. Toxicology and Industrial Health. PMID 25971585 DOI: 10.1177/0748233715584250  0.075
2011 Poeta J, Linden R, Antunes MV, Real L, Menezes AM, Ribeiro JP, Sprinz E. Plasma concentrations of efavirenz are associated with body weight in HIV-positive individuals. The Journal of Antimicrobial Chemotherapy. 66: 2601-4. PMID 21890538 DOI: 10.1093/jac/dkr360  0.075
1991 Serfaty CA, Linden R. Evidence that the relative densities of afferents from both eyes control laminar distribution and binocular segregation of retinotectal projections in rats. Brain Research. Developmental Brain Research. 60: 9-17. PMID 1914147 DOI: 10.1016/0165-3806(91)90150-H  0.074
2016 Antunes MV, Charão MF, Linden R. Dried blood spots analysis with mass spectrometry: Potentials and pitfalls in therapeutic drug monitoring. Clinical Biochemistry. PMID 27179588 DOI: 10.1016/j.clinbiochem.2016.05.004  0.074
2023 Rodrigues VB, Menezes JM, da Silva LC, Müller I, Mallmann L, Hermann BS, Menezes C, Brucker N, da Vida RL, Picada JN, Boaretto FBM, Schneider A, Linden R, Zanella R, Fleck JD, et al. as a suitable model to evaluate the toxicity of water from Rolante River, southern Brazil. Toxicology Research. 13: tfad117. PMID 38178995 DOI: 10.1093/toxres/tfad117  0.074
2015 Peteffi GP, Antunes MV, Carrer C, Valandro ET, Santos S, Glaeser J, Mattos L, da Silva LB, Linden R. Environmental and biological monitoring of occupational formaldehyde exposure resulting from the use of products for hair straightening. Environmental Science and Pollution Research International. PMID 26351198 DOI: 10.1007/s11356-015-5343-4  0.073
2018 Peteffi GP, Fleck JD, Kael IM, Girardi V, Bündchen R, Krajeski DM, Demoliner M, Silva FP, da Rosa DC, Antunes MV, Linden R. Caffeine levels as a predictor of Human mastadenovirus presence in surface waters-a case study in the Sinos River basin-Brazil. Environmental Science and Pollution Research International. PMID 29582324 DOI: 10.1007/s11356-018-1649-3  0.073
2020 Dillenburg Weiss TL, Gössling G, Venzon Antunes M, Schwartsmann G, Linden R, Gasparin Verza S. Evaluation of dried blood spots as an alternative matrix for therapeutic drug monitoring of abiraterone and delta(4)-abiraterone in prostate cancer patients. Journal of Pharmaceutical and Biomedical Analysis. 195: 113861. PMID 33373824 DOI: 10.1016/j.jpba.2020.113861  0.071
2019 Capiau S, Veenhof H, Koster RA, Bergqvist Y, Boettcher M, Halmingh O, Keevil BG, Koch BCP, Linden R, Pistos C, Stolk LM, Touw DJ, Stove CP, Alffenaar JC. Official International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot-Based Methods for Therapeutic Drug Monitoring. Therapeutic Drug Monitoring. 41: 409-430. PMID 31268966 DOI: 10.1097/FTD.0000000000000643  0.071
1987 Linden R, Piñon LG. Dual control by targets and afferents of developmental neuronal death in the mammalian central nervous system: a study in the parabigeminal nucleus of the rat. The Journal of Comparative Neurology. 266: 141-9. PMID 3437072 DOI: 10.1002/Cne.902660202  0.07
2022 Carniel E, Dos Santos KA, de Andrade de Lima L, Kohlrausch R, Linden R, Antunes MV. Determination of clozapine and norclozapine in dried plasma spot and dried blood spot by liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 210: 114591. PMID 35033943 DOI: 10.1016/j.jpba.2022.114591  0.07
1984 Cavalcante LA, Rocha-Miranda CE, Linden R. Observations on postnatal neurogenesis in the superior colliculus and the pretectum in the opossum. Brain Research. 315: 241-9. PMID 6722588 DOI: 10.1016/0165-3806(84)90158-5  0.069
2020 Simões-Pires EN, Ferreira ST, Linden R. Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular and Alzheimer's diseases. Journal of Neurochemistry. PMID 32683713 DOI: 10.1111/Jnc.15129  0.069
2021 Hahn RZ, Augusto do Nascimento C, Linden R. Evaluation of Illicit Drug Consumption by Wastewater Analysis Using Polar Organic Chemical Integrative Sampler as a Monitoring Tool. Frontiers in Chemistry. 9: 596875. PMID 33859973 DOI: 10.3389/fchem.2021.596875  0.068
2020 Weiss TLD, Furtado CM, Antunes MV, Gössling G, Schwartsmann G, Linden R, Verza SG. A quick UPLC-MS/MS method for therapeutic drug monitoring of abiraterone and delta(4)-abiraterone (D4A) in human plasma. Biomedical Chromatography : Bmc. e4947. PMID 32652651 DOI: 10.1002/bmc.4947  0.068
1988 Linden R, Renteria AS. Afferent control of neuron numbers in the developing brain Developmental Brain Research. 44: 291-295. PMID 3224429 DOI: 10.1016/0165-3806(88)90227-1  0.067
2017 Hahn RZ, Antunes MV, Costa Arnhold P, Andriguetti NB, Verza SG, Linden R. Determination of topiramate in dried blood spots using single-quadrupole gas chromatography-mass spectrometry after flash methylation with trimethylanilinium hydroxide. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1046: 131-137. PMID 28178597 DOI: 10.1016/j.jchromb.2017.01.047  0.067
2020 Noal Granzotto FC, Cezimbra da Silva AC, Lizot LF, Antunes MV, Linden R. Dried Plasma Spots and Oral Fluid as Alternative Matrices for Therapeutic Drug Monitoring of Busulfan: Analytical Method Development and Clinical Evaluation. Therapeutic Drug Monitoring. PMID 32960547 DOI: 10.1097/FTD.0000000000000807  0.066
2015 Antunes MV, Raymundo S, Wagner SC, Mattevi VS, Vieira N, Leite R, Reginato F, Capra MZ, Fogliatto L, Linden R. DBS sampling in imatinib therapeutic drug monitoring: from method development to clinical application. Bioanalysis. 7: 2105-17. PMID 26327189 DOI: 10.4155/bio.15.101  0.066
2008 da Silva AG, Campello-Costa P, Linden R, Sholl-Franco A. Interleukin-4 blocks proliferation of retinal progenitor cells and increases rod photoreceptor differentiation through distinct signaling pathways. Journal of Neuroimmunology. 196: 82-93. PMID 18378323 DOI: 10.1016/J.Jneuroim.2008.03.003  0.066
2014 Linden R, Ledez K, Hopf H, Fife C. Topical oxygen therapy is not hyperbaric therapy and the two treatments should not be confused. International Wound Journal. 11: 230-1. PMID 22913614 DOI: 10.1111/J.1742-481X.2012.01069.X  0.065
2020 da Silva ACC, de Lima Feltraco Lizot L, Bastiani MF, Venzon Antunes M, Brucker N, Linden R. Dried plasma spots for therapeutic monitoring of amikacin: Validation of an UHPLC-MS/MS assay and pharmacokinetic application. Journal of Pharmaceutical and Biomedical Analysis. 184: 113201. PMID 32113122 DOI: 10.1016/j.jpba.2020.113201  0.065
2013 Antunes MV, Niederauer CG, Linden R. Development, validation and clinical evaluation of a dried urine spot method for determination of hippuric acid and creatinine. Clinical Biochemistry. 46: 1276-80. PMID 23868019 DOI: 10.1016/j.clinbiochem.2013.07.004  0.065
2007 Linden R, Bhaya A. Evolving fuzzy rules to model gene expression. Bio Systems. 88: 76-91. PMID 16870324 DOI: 10.1016/j.biosystems.2006.04.006  0.065
2023 da Silva LC, Grando AP, de Baco LS, Hahn RZ, Ferreira Filho AF, Brucker N, Linden R, Antunes MV. Evaluation of dried blood spots as an alternative sampling strategy for 5-fluorouracil monitoring: From method development to clinical application. Journal of Pharmaceutical and Biomedical Analysis. 235: 115539. PMID 37517245 DOI: 10.1016/j.jpba.2023.115539  0.064
2017 Hahn RZ, Arnhold PC, Andriguetti NB, Schneider A, Klück HM, Dos Reis SL, Bastiani MF, Kael I, da Silva ACC, Schwartsmann G, Antunes MV, Linden R. Determination of irinotecan and its metabolite SN-38 in dried blood spots using high-performance liquid-chromatography with fluorescence detection. Journal of Pharmaceutical and Biomedical Analysis. 150: 51-58. PMID 29216585 DOI: 10.1016/j.jpba.2017.11.079  0.064
2018 Neto OV, Raymundo S, Franzoi MA, do Carmo Artmann A, Tegner M, Müller VV, Hahn RZ, Alves GV, Schwartsmann G, Linden R, Antunes MV. DPD functional tests in plasma, fresh saliva and dried saliva samples as predictors of 5-fluorouracil exposure and occurrence of drug-related severe toxicity. Clinical Biochemistry. PMID 29625079 DOI: 10.1016/j.clinbiochem.2018.04.001  0.064
2017 da Silva ACC, Raasch JR, Vargas TG, Peteffi GP, Hahn RZ, Antunes MV, Perassolo MS, Linden R. Simultaneous determination of fluoxetine and norfluoxetine in dried blood spots using high-performance liquid chromatography-tandem mass spectrometry. Clinical Biochemistry. PMID 28987790 DOI: 10.1016/j.clinbiochem.2017.10.002  0.063
2022 Müller D, Grevet EH, Figueira da Silva NA, Bandeira CE, Barbosa E, Vitola ES, Charão MF, Linden R, Rohde LA, Ramos JKN, da Silva BS, Rovaris DL, Bau CHD. Global DNA methylation changes in adults with attention deficit-hyperactivity disorder and its comorbidity with bipolar disorder: links with polygenic scores. Molecular Psychiatry. PMID 35256746 DOI: 10.1038/s41380-022-01493-y  0.063
1999 Rocha M, Martins RA, Linden R. Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins. Brain Research. 827: 79-92. PMID 10320696 DOI: 10.1016/S0006-8993(99)01307-4  0.062
2020 Manfro ID, Tegner M, Krutzmann ME, Artmann ADC, Brandeburski MR, Peteffi GP, Linden R, Antunes MV. Determination of lithium in dried blood spots and dried plasma spots by graphite furnace atomic absorption spectrometry: Method development, validation and clinical application. Talanta. 216: 120907. PMID 32456895 DOI: 10.1016/j.talanta.2020.120907  0.062
2021 Janner DR, de Lima EV, da Silva RT, Clarke JR, Linden R. Dissociation of genotype-dependent cognitive and motor behavior in a strain of aging mice devoid of the prion protein. Behavioural Brain Research. 411: 113386. PMID 34052264 DOI: 10.1016/j.bbr.2021.113386  0.062
2014 Rhoden L, Antunes MV, Hidalgo P, Álvares da Silva C, Linden R. Simple procedure for determination of valproic acid in dried blood spots by gas chromatography-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 96: 207-12. PMID 24769300 DOI: 10.1016/j.jpba.2014.03.044  0.062
2011 Martins DH, Wagner SC, Dos Santos TV, Lizot Lde L, Antunes MV, Capra M, Linden R. Monitoring imatinib plasma concentrations in chronic myeloid leukemia. Revista Brasileira De Hematologia E Hemoterapia. 33: 302-6. PMID 23049322 DOI: 10.5581/1516-8484.20110081  0.06
2015 Moro AM, Brucker N, Charão MF, Sauer E, Freitas F, Durgante J, Bubols G, Campanharo S, Linden R, Souza AP, Bonorino C, Moresco R, Pilger D, Gioda A, Farsky S, et al. Early hematological and immunological alterations in gasoline station attendants exposed to benzene. Environmental Research. 137: 349-56. PMID 25601738 DOI: 10.1016/j.envres.2014.11.003  0.06
2007 Derringer K, Linden R. Epidermal growth factor released in human dental pulp following orthodontic force. European Journal of Orthodontics. 29: 67-71. PMID 17290017 DOI: 10.1093/ejo/cjl059  0.06
2013 Antunes MV, Rosa DD, Viana Tdos S, Andreolla H, Fontanive TO, Linden R. Sensitive HPLC-PDA determination of tamoxifen and its metabolites N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 76: 13-20. PMID 23291438 DOI: 10.1016/j.jpba.2012.12.005  0.06
2023 Lizot LLF, Bastiani MF, Hahn RZ, Meireles YF, Freitas M, Bondan AP, do Nascimento CA, Quevedo DM, Linden R. Risk assessment of a Brazilian urban population due to the exposure to pyrethroid insecticides during the COVID-19 pandemic using wastewater-based epidemiology. Chemosphere. 345: 140526. PMID 37879376 DOI: 10.1016/j.chemosphere.2023.140526  0.059
1983 Linden R, Perry VH. Retrograde and anterograde-transneuronal degeneration in the parabigeminal nucleus following tectal lesions in developing rats. The Journal of Comparative Neurology. 218: 270-81. PMID 6886075 DOI: 10.1002/Cne.902180304  0.059
2017 Becker DF, Linden R, Schmitt JL. Richness, coverage and concentration of heavy metals in vascular epiphytes along an urbanization gradient. The Science of the Total Environment. 584: 48-54. PMID 28135612 DOI: 10.1016/j.scitotenv.2017.01.092  0.059
2015 Linden R, Antunes MV, Heinzelmann LS, Fleck JD, Staggemeier R, Fabres RB, Vecchia AD, Nascimento CA, Spilki FR. Caffeine as an indicator of human fecal contamination in the Sinos River: a preliminary study. Brazilian Journal of Biology = Revista Brasleira De Biologia. 75: 81-4. PMID 26270218 DOI: 10.1590/1519-6984.0513  0.058
2018 Andriguetti NB, Lisboa LL, Hahn SR, Pagnussat LR, Antunes MV, Linden R. Simultaneous determination of vancomycin and creatinine in plasma applied to volumetric absorptive microsampling devices using liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 165: 315-324. PMID 30579232 DOI: 10.1016/j.jpba.2018.12.023  0.058
2002 Borges VM, Lopes MF, Falcão H, Leite-Júnior JH, Rocco PR, Davidson WF, Linden R, Zin WA, DosReis GA. Apoptosis underlies immunopathogenic mechanisms in acute silicosis. American Journal of Respiratory Cell and Molecular Biology. 27: 78-84. PMID 12091249 DOI: 10.1165/Ajrcmb.27.1.4717  0.057
2015 Beckman D, Santos LE, Americo TA, Ledo JH, de Mello FG, Linden R. Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice. The Journal of Biological Chemistry. 290: 20488-98. PMID 26152722 DOI: 10.1074/Jbc.M115.666156  0.057
2015 Hollmann G, Ferreira Gde J, Geihs MA, Vargas MA, Nery LE, Leitão Á, Linden R, Allodi S. Antioxidant activity stimulated by ultraviolet radiation in the nervous system of a crustacean. Aquatic Toxicology (Amsterdam, Netherlands). 160: 151-62. PMID 25630046 DOI: 10.1016/J.Aquatox.2015.01.008  0.057
2021 Schaefer VD, de Lima Feltraco Lizot L, Hahn RZ, Schneider A, Antunes MV, Linden R. Simple determination of valproic acid serum concentrations using BioSPME followed by gas chromatography-mass spectrometric analysis. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1167: 122574. PMID 33621796 DOI: 10.1016/j.jchromb.2021.122574  0.056
2023 Müller IR, Linden G, Charão MF, Antunes MV, Linden R. Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities. Expert Review of Clinical Pharmacology. 1-11. PMID 37300458 DOI: 10.1080/17512433.2023.2224562  0.055
2018 Raymundo S, Muller VV, Andriguetti NB, Tegner M, Artmann AC, Kluck HM, Franzoi MA, Vilela RMM, Schwartsmann G, Linden R, Antunes MV. Determination of docetaxel in dried blood spots by LC-MS/MS: Method development, validation and clinical application. Journal of Pharmaceutical and Biomedical Analysis. 157: 84-91. PMID 29775811 DOI: 10.1016/j.jpba.2018.05.011  0.055
2002 LINDEN R. Methionine therapy in liver disease. Canadian Medical Association Journal. 75: 680-1. PMID 13364814  0.055
1976 Rocha-Miranda CE, Linden R, Volchan E, Lent R, Bombar-Dieri RA. Receptive field properties of single units in the opossum striate cortex. Brain Research. 104: 197-219. PMID 816419 DOI: 10.1016/0006-8993(76)90614-4  0.055
2010 Linden R, Feltraco LL, Comerlato LC, Kellermann E, Antunes MV. Computer assisted substance identification in systematic toxicological analysis: New life for old methods? Forensic Science International. 202: e53-60. PMID 20554409 DOI: 10.1016/j.forsciint.2010.05.011  0.054
1981 Linden R, Rocha-Miranda CE. The pretectal complex in the opossum: projections from the striate cortex and correlation with retinal terminal fields. Brain Research. 207: 267-77. PMID 7470909 DOI: 10.1016/0006-8993(81)90364-4  0.054
2018 Wolff FC, Dillenburg TL, Antunes MV, Linden R, Wagner SC, Verza SG. Characterization of imatinib mesylate formulations distributed in South American Countries: determination of genotoxic impurities by UHPLC-MS/MS and dissolution profile. Biomedical Chromatography : Bmc. PMID 29488235 DOI: 10.1002/bmc.4222  0.054
2020 Müller VV, Hahn RZ, Lizot LLF, Schneider A, da Silva CP, Gerbase FE, Pereira D, Linden R, Antunes MV. Validation of an analytical method for the simultaneous determination of 16 drugs and metabolites in hair in the context of driving license granting. Forensic Science International. 315: 110428. PMID 32771886 DOI: 10.1016/j.forsciint.2020.110428  0.053
2022 Hahn RZ, Bastiani MF, Lizot LLF, Schneider A, da Silva Moreira IC, Meireles YF, Viana MF, do Nascimento CA, Linden R. Long-term monitoring of drug consumption patterns during the COVID-19 pandemic in a small-sized community in Brazil through wastewater-based epidemiology. Chemosphere. 302: 134907. PMID 35561781 DOI: 10.1016/j.chemosphere.2022.134907  0.053
2001 Borges VM, Falcão H, Leite-Júnior JH, Alvim L, Teixeira GP, Russo M, Nóbrega AF, Lopes MF, Rocco PM, Davidson WF, Linden R, Yagita H, Zin WA, DosReis GA. Fas ligand triggers pulmonary silicosis. The Journal of Experimental Medicine. 194: 155-64. PMID 11457890 DOI: 10.1084/Jem.194.2.155  0.053
2021 Da Silva CP, Dalpiaz LPP, Gerbase FE, Muller VV, Lizot LLF, Antunes MV, Linden R. Simple extraction of toxicologically relevant psychotropic compounds and metabolites from whole blood using Mini-QuEChERS followed by UPLC-MS/MS analysis. Biomedical Chromatography : Bmc. e5142. PMID 33864392 DOI: 10.1002/bmc.5142  0.053
2015 Antunes MV, Raymundo S, de Oliveira V, Staudt DE, Gössling G, Peteffi GP, Biazús JV, Cavalheiro JA, Tre-Hardy M, Capron A, Haufroid V, Wallemacq P, Schwartsmann G, Linden R. Ultra-high performance liquid chromatography tandem mass spectrometric method for the determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots--development, validation and clinical application during breast cancer adjuvant therapy. Talanta. 132: 775-84. PMID 25476377 DOI: 10.1016/j.talanta.2014.10.040  0.052
2019 da Silva ACC, de Lima Feltraco Lizot L, Bastiani MF, Antunes MV, Brucker N, Linden R. Ready for TDM: Simultaneous quantification of amikacin, vancomycin and creatinine in human plasma employing ultra-performance liquid chromatography-tandem mass spectrometry. Clinical Biochemistry. PMID 31228434 DOI: 10.1016/j.clinbiochem.2019.06.011  0.052
2016 Tré-Hardy M, Capron A, Antunes MV, Linden R, Wallemacq P. Fast method for simultaneous quantification of tamoxifen and metabolites in dried blood spots using an entry level LC-MS/MS system. Clinical Biochemistry. PMID 27498307 DOI: 10.1016/j.clinbiochem.2016.07.018  0.052
2010 Pasqualotto AC, Xavier MO, Andreolla HF, Linden R. Voriconazole therapeutic drug monitoring: focus on safety. Expert Opinion On Drug Safety. 9: 125-37. PMID 20021293 DOI: 10.1517/14740330903485637  0.052
2017 Figueiró LR, Linden R, Ziulkoski AL, Dantas DCM. Cellular effects of thirdhand tobacco smoke from smokers' homes. Toxicology Mechanisms and Methods. 1-9. PMID 29185369 DOI: 10.1080/15376516.2017.1411411  0.051
2014 Charão MF, Moro AM, Valentini J, Brucker N, Bubols GB, Bulcão RP, Baierle M, Freitas FA, Nascimento SN, Barth A, Linden R, Saldiva PH, Garcia SC. Exogenous and endogenous antioxidants attenuate the lipid peroxidation in workers occupationally exposed to paints. Drug and Chemical Toxicology. 37: 69-75. PMID 23841515 DOI: 10.3109/01480545.2013.806534  0.051
2003 Cabral-da-Silva MC, dos Santos NE, de Mello FG, Taylor JS, Tolkovsky AM, Linden R, Reis RA. Herbimycin A induces sympathetic neuron survival and protects against hypoxia. Neuroreport. 14: 2397-401. PMID 14663199 DOI: 10.1097/00001756-200312190-00022  0.05
2004 Pinto DO, Ferreira PL, Andrade LR, Petrs-Silva H, Linden R, Abdelhay E, Araújo HM, Alonso CE, Pavão MS. Biosynthesis and metabolism of sulfated glycosaminoglycans during Drosophila melanogaster development. Glycobiology. 14: 529-36. PMID 15044397 DOI: 10.1093/Glycob/Cwh070  0.05
2021 Schaefer VD, Müller VV, Feltraco Lizot LL, Hahn RZ, Schneider A, Antunes MV, Linden R. Sensitive determination of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol and complementary cannabinoids in hair using alkaline digestion and mixed-mode solid phase extraction followed by liquid-chromatography-tandem mass spectrometry. Forensic Science International. 328: 111047. PMID 34649099 DOI: 10.1016/j.forsciint.2021.111047  0.05
2015 Capron A, Antunes MV, Wagner SC, Mattevi VS, Vieira N, Leite R, Reginato F, Capra M, Fogliatto L, Wallemacq P, Linden R. First report of imatinib measurement in hair: Method development and preliminary evaluation of the relation between hair and plasma concentrations with therapeutic response in chronic myeloid leukemia. Clinica Chimica Acta; International Journal of Clinical Chemistry. 453: 42-47. PMID 26657979 DOI: 10.1016/j.cca.2015.11.032  0.049
2019 Bastiani MF, Lizot LLF, Da Silva ACC, Hahn RZ, Dries SS, Perassolo MS, Antunes MV, Linden R. Improved measurement of ethyl glucuronide concentrations in hair using UPLCMS/MS for the evaluation of chronic ethanol consumption. Forensic Science International. 306: 110071. PMID 31785510 DOI: 10.1016/j.forsciint.2019.110071  0.049
2020 Da Silva CP, Dalpiaz LPP, Gerbase FE, Muller VV, Cezimbra da Silva A, Lizot LL, Hahn R, Costa JL, Antunes MV, Linden R. Determination of cannabinoids in plasma using salting-out assisted liquid-liquid extraction followed by LC-MS/MS analysis. Biomedical Chromatography : Bmc. e4952. PMID 32706449 DOI: 10.1002/bmc.4952  0.049
2019 Lizot LLF, da Silva ACC, Bastiani MF, Maurer TF, Hahn RZ, Perassolo MS, Antunes MV, Linden R. Simultaneous Determination of Cocaine and Metabolites in Human Plasma Using Solid Phase Micro-Extraction Fiber Tips C18 and UPLC-MS/MS. Journal of Analytical Toxicology. PMID 31095712 DOI: 10.1093/jat/bkz042  0.049
2015 Beckman D, Santos LE, Americo TA, Ledo JH, de Mello FG, Linden R. Reply to Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice. The Journal of Biological Chemistry. 290: 26351. PMID 26500296 DOI: 10.1074/Jbc.L115.689232  0.049
2022 Menestrina Dewes M, Cé da Silva L, Fazenda Meireles Y, Viana de Freitas M, Frank Bastiani M, Feltraco Lizot L, Zilles Hahn R, Venzon Antunes M, Linden R. Evaluation of the Tasso-SST® capillary blood microsampling device for the measurement of endogenous uracil levels. Clinical Biochemistry. PMID 35709975 DOI: 10.1016/j.clinbiochem.2022.06.003  0.048
2011 O'Reilly D, Linden R, Fedorko L, Tarride JE, Jones WG, Bowen JM, Goeree R. A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive hyperbaric oxygen therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients with diabetes mellitus: a study protocol. Trials. 12: 69. PMID 21385365 DOI: 10.1186/1745-6215-12-69  0.048
2015 Hahn RZ, Galarza AF, Schneider A, Antunes MV, Schwartsmann G, Linden R. Improved determination of uracil and dihydrouracil in plasma after a loading oral dose of uracil using high-performance liquid chromatography with photodiode array detection and porous graphitic carbon stationary phase. Clinical Biochemistry. PMID 25940841 DOI: 10.1016/j.clinbiochem.2015.04.019  0.048
2022 Tegner M, Ott IR, de Souza Guterres F, de Barros VM, Linden R, Antunes MV. Determination of Ethyl Glucuronide and Ethyl Sulfate in Dried Blood Spots by UHPLC-MS-MS: Method Validation and Assessment of Ethanol Exposure in Postmortem Samples from Road Traffic Victims. Journal of Analytical Toxicology. PMID 36087096 DOI: 10.1093/jat/bkac074  0.048
1994 Bosco A, Linden R, Carri NG. Expression of alpha-1 integrin subunit in the mammalian retina. Cell Biology International. 18: 211-3. PMID 8019496 DOI: 10.1006/Cbir.1994.1064  0.047
2020 de Franceschi ID, da Silva JD, Minuzzi BN, de Barros KC, Fernandes EK, Bortoluzzi VT, Rieger E, Preissler T, Feksa LR, Hahn RZ, Linden R, Rech VC, Casalli EA, Wannmacher CMD. Ibuprofen during gestation prevents some changes in physical and reflex development in offspring in a model of hyperleucinemia and maternal inflammation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 32379904 DOI: 10.1002/jdn.10035  0.047
1991 Linden RM, Schilling BC, Germann UA, Lerch K. Regulation of laccase synthesis in induced Neurospora crassa cultures. Current Genetics. 19: 375-81. PMID 1833078  0.046
2015 Antunes MV, Timm TA, de Oliveira V, Staudt DE, Raymundo S, Gössling G, Biazús JV, Cavalheiro JA, Rosa DD, Wallemacq P, Haufroid V, Linden R, Schwartsmann G. Influence of CYP2D6 and CYP3A4 phenotypes, drug interactions and vitamin D status on tamoxifen biotransformation. Therapeutic Drug Monitoring. PMID 25853922 DOI: 10.1097/FTD.0000000000000212  0.046
2019 de Lima Feltraco Lizot L, da Silva ACC, Bastiani MF, Hahn RZ, Bulcão R, Perassolo MS, Antunes MV, Linden R. Simultaneous determination of cocaine, ecgonine methyl ester, benzoylecgonine, cocaethylene and norcocaine in dried blood spots by ultra-performance liquid chromatography coupled to tandem mass spectrometry. Forensic Science International. 298: 408-416. PMID 30954922 DOI: 10.1016/j.forsciint.2019.03.026  0.046
2017 Andriguetti NB, Raymundo S, Antunes MV, Perasolo MS, Verza SG, Suyenaga ES, Linden R. Pharmacogenetic and pharmacokinetic dose individualization of the taxane chemotherapeutic drugs paclitaxel and docetaxel. Current Medicinal Chemistry. PMID 28641556 DOI: 10.2174/0929867324666170623093445  0.046
1983 Linden R, Rocha-Miranda CE. Organization of the visual thalamus: corticothalamic projections from the primary visual area in the opossum. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 16: 247-60. PMID 6652295  0.045
2016 Figueiró LR, Dantas DC, Linden R, Ziulkoski AL. Thirdhand tobacco smoke: procedures to evaluate cytotoxicity in cell cultures. Toxicology Mechanisms and Methods. 1-7. PMID 27268319 DOI: 10.1080/15376516.2016.1188190  0.045
2021 Tomazelli J, Rodrigues GZP, Franco D, de Souza MS, Burghausen JH, Panizzon J, Kayser JM, Loiko MR, Schneider A, Linden R, Gehlen G. Potential use of distinct biomarkers (trace metals, micronuclei, and nuclear abnormalities) in a heterogeneous sample of birds in southern Brazil. Environmental Science and Pollution Research International. PMID 34622404 DOI: 10.1007/s11356-021-16657-6  0.044
2016 Galarza AF, Linden R, Antunes MV, Hahn RZ, Raymundo S, da Silva AC, Staggemeier R, Spilki FR, Schwartsmann G. Endogenous plasma and salivary uracil to dihydrouracil ratios and DPYD genotyping as predictors of severe fluoropyrimidine toxicity in patients with gastrointestinal malignancies. Clinical Biochemistry. PMID 27399164 DOI: 10.1016/j.clinbiochem.2016.07.004  0.044
2023 Lorini Franciscatto I, Scherer Seibert B, Dries SS, Linden R, Ziulkoski AL, Perassolo MS. Evaluation of oxidative stress and its association with drug therapy in inpatients treated for cocaine dependence. Drug and Chemical Toxicology. 1-9. PMID 37259499 DOI: 10.1080/01480545.2023.2219039  0.043
2021 Anibaletto Dos Santos AL, Cezimbra da Silva AC, Feltraco Lizot LL, Schneider A, Meireles YF, Hahn RZ, Pagnussat LR, Nonnenmacher JL, Hahn SR, Linden R. Development and validation of an assay for the measurement of gentamicin concentrations in dried blood spots using UHPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 208: 114448. PMID 34740086 DOI: 10.1016/j.jpba.2021.114448  0.043
2022 Smidt M, Bastiani MF, Hahn RZ, Lima Feltraco Lizot L, Perassolo MS, Linden R. Evaluation of hemaPEN sampling device for measurement of cocaine and metabolites in capillary blood by LC-MS/MS. Bioanalysis. PMID 36468628 DOI: 10.4155/bio-2022-0192  0.043
2020 Bastiani MF, Lizot LLF, Da Silva ACC, Hahn RZ, Dries SS, Perassolo MS, Antunes MV, Linden R. An Optimized Solid-Phase Microextraction and Gas Chromatography-Mass Spectrometry Assay for the Determination of Ethyl Palmitate in Hair. Journal of Analytical Toxicology. PMID 31909801 DOI: 10.1093/jat/bkz085  0.043
2024 de Castilhos Busato MA, Bondan AP, Bastiani MF, Lizot LF, Hahn RZ, Antunes MV, Linden R. Determination of meropenem in capillary plasma microsamples using LC-MS/MS. Bioanalysis. PMID 38497756 DOI: 10.4155/bio-2023-0268  0.041
2019 Rennie MY, Dunham D, Lindvere-Teene L, Raizman R, Hill R, Linden R. Understanding Real-Time Fluorescence Signals from Bacteria and Wound Tissues Observed with the MolecuLight i:X. Diagnostics (Basel, Switzerland). 9. PMID 30813551 DOI: 10.3390/diagnostics9010022  0.041
2020 Antunes MV, Linden R, Schaiquevich P. Therapeutic drug monitoring in developing nations: assessing the current state of affairs in South America. Expert Opinion On Drug Metabolism & Toxicology. PMID 33276703 DOI: 10.1080/17425255.2021.1859478  0.041
2021 Decker Soares DR, Antunes MV, Linden R. Determination of cortisol in hair using liquid chromatography-tandem mass spectrometry: a short review. Bioanalysis. PMID 34187201 DOI: 10.4155/bio-2021-0101  0.04
2023 Linden G, Charão MF, Linden R. Evaluation of the HealthID PSD microsampling device for the simultaneous determination of cholesterol, high-density lipoprotein, triglycerides, creatinine, and HbAc in capillary blood. Clinical Biochemistry. 118: 110597. PMID 37307936 DOI: 10.1016/j.clinbiochem.2023.110597  0.039
2015 Antunes MV, de Oliveira V, Raymundo S, Staudt DE, Gössling G, Biazús JV, Cavalheiro JA, Rosa DD, Mathy G, Wallemacq P, Linden R, Schwartsmann G, Haufroid V. CYP3A4*22 is related to increased plasma levels of 4-hydroxytamoxifen and partially compensates for reduced CYP2D6 activation of tamoxifen. Pharmacogenomics. 16: 601-17. PMID 25893704 DOI: 10.2217/pgs.15.13  0.039
2019 Antunes MV, Raymundo S, Cezimbra da Silva AC, Muller VV, Vicente Neto OJ, Schwartsmann G, Linden R. Determination of endogenous concentrations of uracil and dihydrouracil in dried saliva spots by LC-MS/MS: method development, validation and clinical application. Therapeutic Drug Monitoring. PMID 30807536 DOI: 10.1097/FTD.0000000000000615  0.039
2018 Karppinen N, Lindén R, Sintonen H, Tarkkanen M, Roine R, Heiskanen I, Matikainen N, Schalin-Jäntti C. Health-Related Quality of Life in Patients with Small Intestine Neuroendocrine Tumours. Neuroendocrinology. PMID 30293074 DOI: 10.1159/000494293  0.038
2015 DaCosta RS, Kulbatski I, Lindvere-Teene L, Starr D, Blackmore K, Silver JI, Opoku J, Wu YC, Medeiros PJ, Xu W, Xu L, Wilson BC, Rosen C, Linden R. Point-of-care autofluorescence imaging for real-time sampling and treatment guidance of bioburden in chronic wounds: first-in-human results. Plos One. 10: e0116623. PMID 25790480 DOI: 10.1371/journal.pone.0116623  0.038
2010 Moro AM, Charão M, Brucker N, Bulcão R, Freitas F, Guerreiro G, Baierle M, Nascimento S, Waechter F, Hirakata V, Linden R, Thiesen FV, Garcia SC. Effects of low-level exposure to xenobiotics present in paints on oxidative stress in workers. The Science of the Total Environment. 408: 4461-7. PMID 20655097 DOI: 10.1016/j.scitotenv.2010.06.058  0.038
2024 Müller IR, Grandi VT, Santos Paulino SG, Villa B, Zembruski BM, Forcelini CM, Hahn SR, Antunes MV, Linden R. Determination of carbamazepine in fingerprints: a feasibility study to evaluate adherence in epilepsy patients. Bioanalysis. PMID 38497729 DOI: 10.4155/bio-2023-0265  0.037
2023 Schneider A, Lima Feltraco Lizot L, Reginatto GC, Hahn RZ, Bastiani MF, Bondan AP, Perassolo MS, Linden R. Determination of amphetamines, opioids, cocaine metabolites and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in urine using biocompatible solid-phase microextraction and ultra-performance LC-MS/MS. Bioanalysis. PMID 37354101 DOI: 10.4155/bio-2023-0094  0.036
2003 LINDEN R. [What the physician is allowed to deduct from his income tax. IX..]. Die Medizinische. 26: 889-90; contd. PMID 13086235  0.036
1986 Linden R. Materials management's role in product line development. Hospital Material[Dollar Sign] Management. 11: 8-12. PMID 10311583  0.035
2019 Scribel L, Zavascki AP, Matos D, Silveira F, Peralta T, Gonçalves Landgraf N, Lamb Wink P, Cezimbra da Silva AC, Bordin Andriguetti N, Loss Lisboa L, Venzon Antunes M, Linden R. Vancomycin and creatinine determination in dried blood spots: Analytical validation and clinical assessment. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1137: 121897. PMID 31891859 DOI: 10.1016/j.jchromb.2019.121897  0.035
2015 Wu YC, Smith M, Chu A, Lindvere-Teene L, Starr D, Tapang K, Shekhman R, Wong O, Linden R, DaCosta RS. Handheld fluorescence imaging device detects subclinical wound infection in an asymptomatic patient with chronic diabetic foot ulcer: a case report. International Wound Journal. PMID 25907362 DOI: 10.1111/iwj.12451  0.035
2022 Nowak DA, Linden R, Arnold P, Seitz V, Stangl K, Wendl C, Schlachetzki F. Case report: A complicated course of Collet-Sicard syndrome after internal carotid artery dissection and lenticulo-striatal artery infarction. Frontiers in Neurology. 13: 939236. PMID 36341084 DOI: 10.3389/fneur.2022.939236  0.034
2014 Antunes MV, Staudt DE, Raymundo S, de Oliveira V, Gössling G, Pirolli R, Biazús JV, Cavalheiro JA, Rosa DD, Schwartsmann G, Linden R. Development, validation and clinical application of a HPLC-FL method for CYP2D6 phenotyping in South Brazilian breast cancer patients. Clinical Biochemistry. 47: 1084-90. PMID 24747158 DOI: 10.1016/j.clinbiochem.2014.04.008  0.034
2021 Sistonen HJ, Aro K, Atula T, Jouhi L, Lindén R, Tapiovaara L, Loimu V, Markkola A. Prognostic Value of Apparent Diffusion Coefficient in Oropharyngeal Carcinoma. Clinical Neuroradiology. PMID 33877396 DOI: 10.1007/s00062-021-01014-4  0.034
2021 Anibaletto Dos Santos AL, Cezimbra da Silva AC, de Lima Feltraco Lizot L, Schneider A, Hahn RZ, Meireles YF, Pagnussat LR, Nonnenmacher JL, Hahn SR, Linden R. Sensitive determination of gentamicin in plasma using ion-exchange solid-phase extraction followed by UHPLC-MS/MS analysis. Practical Laboratory Medicine. 26: e00246. PMID 34337126 DOI: 10.1016/j.plabm.2021.e00246  0.034
2017 Ottolino-Perry K, Chamma E, Blackmore KM, Lindvere-Teene L, Starr D, Tapang K, Rosen CF, Pitcher B, Panzarella T, Linden R, DaCosta RS. Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers. International Wound Journal. PMID 28244218 DOI: 10.1111/iwj.12717  0.034
2000 LINDEN R. [Current income tax problems; medical expenses as maintenance costs in typical cases of occupational disease in a physician]. Die Medizinische. 2: 97-8. PMID 13516223  0.033
2023 E Silva LS, Machado CDSB, Linden R, Antunes MV, da Silva LC, Wayhs CAY, Capp E, Ness SLR. Residual contamination in antineoplastic drug packaging. Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners. 10781552231151693. PMID 36659825 DOI: 10.1177/10781552231151693  0.032
2011 Moreira MC, Lara GM, Linden R, Feksa LR, Tavares RG, Almeida SE, Berlese DB. Frequency of the anti-glutamic acid decarboxylase immunological marker in patients with diabetes duration longer than three years in southern Brazil. SãO Paulo Medical Journal = Revista Paulista De Medicina. 129: 130-3. PMID 21755246  0.032
2023 Bondan AP, Linden R. Capillary plasma separation microsampling devices: a solution for dried blood spot limitations in clinical testing. Bioanalysis. 15: 591-593. PMID 37350402 DOI: 10.4155/bio-2023-0109  0.032
2018 Peteffi GP, Fleck JD, Kael IM, Rosa DC, Antunes MV, Linden R. Ecotoxicological risk assessment due to the presence of bisphenol A and caffeine in surface waters in the Sinos River Basin - Rio Grande do Sul - Brazil. Brazilian Journal of Biology = Revista Brasleira De Biologia. PMID 30427383 DOI: 10.1590/1519-6984.189752  0.031
2021 Decker Soares DR, Bastiani MF, Schneider A, Hahn RZ, Lizot LF, Perassolo MS, Antunes MV, Linden R. Determination of cortisol in hair using UHPLC-MS/MS: application to patients admitted for ethanol dependence treatment. Bioanalysis. PMID 34636657 DOI: 10.4155/bio-2021-0170  0.03
1999 Linden R. Using a copper band to isolate severely broken teeth before endodontic procedures. Journal of the American Dental Association (1939). 130: 1095. PMID 10422405  0.03
2000 LINDEN R. [Tax deductibility of expenses for medical conferences in foreign countries]. Die Medizinische. 3: 727-9. PMID 13551707  0.03
2003 LINDEN R. [Explanation for the 1952 income tax]. Die Medizinische. 21: 825-6. PMID 13071396  0.029
1996 Linden R. A simple technique for manipulating small prosthetic restorations. Journal of the American Dental Association (1939). 127: 1378. PMID 8854616  0.029
2020 Dries SS, Seibert BS, Bastiani MF, Linden R, Perassolo MS. Evaluation of oxidative stress biomarkers and liver and renal functional parameters in patients during treatment a mental health unit to treat alcohol dependence. Drug and Chemical Toxicology. 1-7. PMID 32567384 DOI: 10.1080/01480545.2020.1780251  0.029
2019 Raizman R, Dunham D, Lindvere-Teene L, Jones LM, Tapang K, Linden R, Rennie MY. Use of a bacterial fluorescence imaging device: wound measurement, bacterial detection and targeted debridement. Journal of Wound Care. 28: 824-834. PMID 31825778 DOI: 10.12968/jowc.2019.28.12.824  0.029
2003 LINDEN R. [Use of special tax rates on income from medical testimony]. Die Medizinische. 359-61. PMID 13321422  0.029
2013 Arpini J, Antunes MV, Pacheco LS, Gnatta D, Rodrigues MF, Keitel E, Linden R. Clinical evaluation of a dried blood spot method for determination of mycophenolic acid in renal transplant patients. Clinical Biochemistry. 46: 1905-8. PMID 24161478 DOI: 10.1016/j.clinbiochem.2013.10.011  0.028
1970 Linden R. [Are the expenses for my practice correct? Aid for comparison with the figures of official statistics]. Zahnarztliche Mitteilungen. 59: 1183-4. PMID 5262771  0.027
2002 LINDEN R. [Is the doctor permitted to declare depreciation of roentgen instruments in his income tax return?]. Die Medizinische. 1028-9. PMID 13451051  0.027
2011 Groh A, Linden R. Addressing elder abuse: the Waterloo restorative justice approach to elder abuse project. Journal of Elder Abuse & Neglect. 23: 127-46. PMID 21462047 DOI: 10.1080/08946566.2011.558780  0.027
2002 LINDEN R. [Income tax of pediatricians]. Die Medizinische. 7: 1004-5. PMID 13358432  0.026
2017 De Capitani EM, Borrasca-Fernandes CF, Branco Pimenta M, Prado CC, Soubhia PC, Lanaro R, Mello Moreira S, Linden R, Nóbrega HV, Bucaretchi F, Costa JL. Suicide attempt with acetonitrile ingestion in a nursing mother. Clinical Toxicology (Philadelphia, Pa.). 1-5. PMID 28494173 DOI: 10.1080/15563650.2017.1324977  0.026
2023 Moraes L, Dries SS, Seibert BS, Linden R, Perassolo MS. Evaluation of oxidative stress markers in ethanol users. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 56: e12465. PMID 36856254 DOI: 10.1590/1414-431X2023e12465  0.025
2003 LINDEN R. [What the physician can deduct in his income tax return; an ABC of office expenses, advertising costs, special expenses and tax allowances]. Die Medizinische. 6: 31-2. PMID 13054302  0.025
1986 Linden R. Product line cost accounting: an overview. Hospital Material[Dollar Sign] Management. 11: 11-4. PMID 10278411  0.025
2015 Ponfick M, Linden R, Nowak DA. Dysphagia--a common, transient symptom in critical illness polyneuropathy: a fiberoptic endoscopic evaluation of swallowing study*. Critical Care Medicine. 43: 365-72. PMID 25377021 DOI: 10.1097/CCM.0000000000000705  0.023
2017 Renkonen S, Lindén R, Bäck L, Silén R, Mäenpää H, Tapiovaara L, Aro K. Accuracy of preoperative MRI to assess lateral neck metastases in papillary thyroid carcinoma. European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (Eufos) : Affiliated With the German Society For Oto-Rhino-Laryngology - Head and Neck Surgery. PMID 28866793 DOI: 10.1007/s00405-017-4728-z  0.023
2020 Fontanive TO, Dick NRM, Valente MCS, Laranjeira VDS, Antunes MV, Corrêa MP, Alves RCM, Linden R, Furlanetto TW. Seasonal variation of vitamin D among healthy adult men in a subtropical region. Revista Da Associacao Medica Brasileira (1992). 66: 1431-1436. PMID 33174939 DOI: 10.1590/1806-9282.66.10.1431  0.023
2015 Antunes MV, da Silva CF, Finger MA, Moore C, Linden R. Correlation analysis between cotinine hair concentrations from active smokers and nicotine intake and dependence. Therapeutic Drug Monitoring. 37: 405-7. PMID 25254413 DOI: 10.1097/FTD.0000000000000140  0.023
2022 Linden R, Vassilaki M, Henderson EJ, Mohan D. Editorial: Multimorbidity in the context of neurodegenerative disorders. Frontiers in Neuroscience. 16: 1076486. PMID 36483182 DOI: 10.3389/fnins.2022.1076486  0.023
1983 Newkirk W, Linden R. EMS management: improving communication through active listening. Emergency Medical Services. 11: 8, 10-1. PMID 10261539  0.023
2020 Gerbase FE, Tegner M, Krutzmann ME, Muller VV, Alff JA, da Silva VB, Sagrilo OP, Linden R, Antunes MV. Blood phosphatidyl ethanol levels as a tool to detect alcohol misuse in trauma patients. Clinical Toxicology (Philadelphia, Pa.). 1-8. PMID 33021410 DOI: 10.1080/15563650.2020.1822531  0.023
2003 LINDEN R. [Scientific activities of physicians favored by tax policy]. Die Medizinische. 21: 589. PMID 13071328  0.019
2003 LINDEN R. [Physician's income tax deductions. VII]. Die Medizinische. 21: 423-5; contd. PMID 13071278  0.018
2000 Linden R, Ortega GG, Petrovick PR, Bassani VL. Response surface analysis applied to the preparation of tablets containing a high concentration of vegetable spray-dried extract. Drug Development and Industrial Pharmacy. 26: 441-6. PMID 10769786 DOI: 10.1081/DDC-100101251  0.018
2003 LINDEN R. [Physician's income tax deductions]. Die Medizinische. 21: 166. PMID 13063083  0.018
2008 Vasques CA, Rossetto S, Halmenschlager G, Linden R, Heckler E, Fernandez MS, Alonso JL. Evaluation of the pharmacotherapeutic efficacy of Garcinia cambogia plus Amorphophallus konjac for the treatment of obesity. Phytotherapy Research : Ptr. 22: 1135-40. PMID 18729243 DOI: 10.1002/ptr.2323  0.018
2016 Aaltonen G, Keränen I, Carpelan-Holmström M, Savolainen R, Lindén R, Lepistö A. Intra-Abdominal Adhesions Make the Interpretation of Magnetic Resonance Enterography in Crohn's Disease More Difficult. Digestive Surgery. 34: 30-35. PMID 27384313 DOI: 10.1159/000447721  0.018
2003 LINDEN R. [Physician's income tax deductions. XIII..]. Die Medizinische. 4: 132-3; contd. PMID 13144197  0.017
2003 LINDEN R. [Physicians deduction from income tax]. Die Medizinische. 13: 440-1. PMID 13175930  0.017
2003 LINDEN R. [What the physician can deduct from his income tax]. Die Medizinische. 21: 356-7; contd. PMID 13071255  0.017
2003 LINDEN R. [What the physician can deduct in his income tax return. III]. Die Medizinische. 6: 132; contd. PMID 13054334  0.017
2003 LINDEN R. [Moderation of taxes for war-disabled doctors]. Die Medizinische. 6: 96-7. PMID 13054324  0.017
1998 LINDEN R. [Sales tax exemption for medical aids]. Die Medizinische Welt. 7: 392-5. PMID 14417107  0.017
2003 LINDEN R. [Physician's income deduction. VIII]. Die Medizinische. 21: 857-9; contd. PMID 13071405  0.016
2022 Kostiainen I, Karppinen N, Simonen P, Rosengård-Bärlund M, Lindén R, Tarkkanen M, Gordin D, Rapola J, Schalin-Jäntti C, Matikainen N. Arterial function, biomarkers, carcinoid syndrome and carcinoid heart disease in patients with small intestinal neuroendocrine tumours. Endocrine. PMID 35536452 DOI: 10.1007/s12020-022-03065-0  0.014
2003 LINDEN R. [Several questions of income tax return in 1954]. Die Medizinische. 19: 720-2. PMID 14393392  0.014
1987 Linden R, Byrd BF. Superior vena cava Doppler: a non-invasive method for the diagnosis of pericardial disease. International Journal of Cardiology. 16: 145-53. PMID 2957326 DOI: 10.1016/0167-5273(87)90245-2  0.013
2017 Rennie MY, Lindvere-Teene L, Tapang K, Linden R. Point-of-care fluorescence imaging predicts the presence of pathogenic bacteria in wounds: a clinical study. Journal of Wound Care. 26: 452-460. PMID 28795890 DOI: 10.12968/jowc.2017.26.8.452  0.013
2003 LINDEN R. [Problem of physician's income tax]. Medizinische Monatsschrift. 7: 56. PMID 13071569  0.013
2003 LINDEN R. [The physician's income-tax deductions beginning with 1955; new deductions in taxation]. Die Medizinische. 2: 93-4. PMID 14355461  0.012
2003 LINDEN R. [Which physician should pay capital gains tax?]. Die Medizinische. 199-201. PMID 13308680  0.012
1972 Linden R. [Medical records for general practice]. Zeitschrift Fur Allgemeinmedizin. 46: 407-8. PMID 5522748  0.012
1978 Johnson SD, Gibson L, Linden R. Alcohol and rape in Winnipeg, 1966-1975 Journal of Studies On Alcohol. 39: 1887-1894. PMID 739769  0.011
1973 Rocha-Miranda CE, Bombardieri RA, de Monasterio FM, Linden R. Receptive fields in the visual cortex of the opossum. Brain Research. 63: 362-7. PMID 4764305 DOI: 10.1016/0006-8993(73)90105-4  0.011
2003 LINDEN R. [Income tax problems of physicians]. Die Medizinische. 233-4. PMID 13308689  0.01
2006 Hopfiald J, Linden RM, Tevelow BJ. Getting patients to take their medicine McKinsey Quarterly. 14-17.  0.01
2005 Linden R. The surfer wears a suit. A report on the II Symposium on Creativity, Imagination and Interactivity in Science Education. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 38: 315-9. PMID 15761610 DOI: 10.1590/S0100-879X2005000300001  0.01
2004 Pihakari A, Rintala J, Kitti U, Könönen M, Linden R, Peltola J, Santavirta S, Konttinen YT. [Tooth implant--a spare part becoming commonly used]. Duodecim; Lã¤ã¤Ketieteellinen Aikakauskirja. 120: 1474-82. PMID 15293708  0.01
2004 Linden R. Funding research. Journal of the American Dental Association (1939). 135: 566, 568. PMID 15202746  0.01
2003 LINDEN R. [Tax reform of 1953 and the physician]. Die Medizinische. 925. PMID 13086246  0.01
2003 LINDEN R. [Are physicians permitted to deduct travel expenses?]. Die Medizinische. 21: 464-6. PMID 13071291  0.01
2002 LINDEN R. Nephrectomy in hypertension. Canadian Medical Association Journal. 75: 682-3. PMID 13364816  0.01
2000 LINDEN R. [Official depreciation tables for institutions & in private practice of health]. Die Medizinische. 2: 285-6. PMID 13516268  0.01
1998 Schiller VL, Raft E, Linden R. Uterine arteriovenous malformation. Ajr. American Journal of Roentgenology. 170: 219-20. PMID 9423639 DOI: 10.2214/ajr.170.1.9423639  0.01
1993 Spengler RW, Braun CA, Linden RM, Martin LG, Ross-Brown DM, Blackburn RL. Structural character of the Ghost Dance fault, Yucca Mountain, Nevada High Level Radioactive Waste Management. 653-659.  0.01
1979 Currie R, Driedger L, Linden R. Abstinence and moderation: mixing Mennonite drinking norms. The Mennonite Quarterly Review. 53: 263-81. PMID 11620386  0.01
1975 Matthews B, Searle BN, Adams D, Linden R. Thresholds of vital and non-vital teeth to stimulation with electric pulp testers. British Dental Journal. 137: 352-5. PMID 4531348 DOI: 10.1038/sj.bdj.4803321  0.01
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