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Spyridon Theofilopoulos - Publications

Affiliations: 
2007-2015 MBB Karolinska Institute, Stockholm, Sweden 
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hennegan J, Bryant AH, Griffiths L, Trigano M, Bartley OJM, Bartlett JJ, Minahan C, Abreu de Oliveira WA, Yutuc E, Ntikas S, Bartsocas CS, Markouri M, Antoniadou E, Laina I, Howell OW, ... ... Theofilopoulos S, et al. Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development. Iscience. 27: 108670. PMID 38155767 DOI: 10.1016/j.isci.2023.108670  0.38
2021 Griffiths WJ, Abdel-Khalik J, Moore SF, Wijeyekoon RS, Crick PJ, Yutuc E, Farrell K, Breen DP, Williams-Gray CH, Theofilopoulos S, Arenas E, Trupp M, Barker RA, Wang Y. The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features. Frontiers in Aging Neuroscience. 13: 685594. PMID 34526889 DOI: 10.3389/fnagi.2021.685594  0.487
2019 Meljon A, Crick PJ, Yutuc E, Yau JL, Seckl JR, Theofilopoulos S, Arenas E, Wang Y, Griffiths WJ. Mining for Oxysterols in Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. Biomolecules. 9. PMID 31013940 DOI: 10.3390/biom9040149  0.531
2019 Theofilopoulos S, Abreu de Oliveira WA, Yang S, Yutuc E, Saeed A, Abdel-Khalik J, Ullgren A, Cedazo-Minguez A, Björkhem I, Wang Y, Griffiths WJ, Arenas E. 24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis . The Journal of Biological Chemistry. PMID 30655290 DOI: 10.1074/Jbc.Ra118.005639  0.798
2018 Griffiths WJ, Crick PJ, Meljon A, Theofilopoulos S, Abdel-Khalik J, Yutuc E, Parker JE, Kelly DE, Kelly SL, Arenas E, Wang Y. Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 30471425 DOI: 10.1016/J.Bbalip.2018.11.006  0.625
2018 Gyllborg D, Ahmed M, Toledo EM, Theofilopoulos S, Yang S, Ffrench-Constant C, Arenas E. The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation. Stem Cell Reports. PMID 30146491 DOI: 10.1016/J.Stemcr.2018.07.014  0.706
2016 Hedlund E, Belnoue L, Theofilopoulos S, Salto C, Bye C, Parish C, Deng Q, Kadkhodaei B, Ericson J, Arenas E, Perlmann T, Simon A. Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors. Scientific Reports. 6: 26448. PMID 27246266 DOI: 10.1038/Srep26448  0.742
2015 Theofilopoulos S, Arenas E. Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration. F1000prime Reports. 7: 37. PMID 26097711 DOI: 10.12703/P7-37  0.68
2014 Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, et al. Cholestenoic acids regulate motor neuron survival via liver X receptors. The Journal of Clinical Investigation. 124: 4829-42. PMID 25271621 DOI: 10.1172/Jci68506  0.754
2013 Theofilopoulos S, Wang Y, Kitambi SS, Sacchetti P, Sousa KM, Bodin K, Kirk J, Saltó C, Gustafsson M, Toledo EM, Karu K, Gustafsson JÃ…, Steffensen KR, Ernfors P, Sjövall J, et al. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nature Chemical Biology. 9: 126-33. PMID 23292650 DOI: 10.1038/Nchembio.1156  0.783
2013 ÄŒajánek L, Ganji RS, Henriques-Oliveira C, Theofilopoulos S, Koník P, Bryja V, Arenas E. Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. Molecular and Cellular Biology. 33: 59-70. PMID 23109420 DOI: 10.1128/Mcb.00745-12  0.746
2012 Meljon A, Theofilopoulos S, Shackleton CH, Watson GL, Javitt NB, Knölker HJ, Saini R, Arenas E, Wang Y, Griffiths WJ. Analysis of bioactive oxysterols in newborn mouse brain by LC/MS. Journal of Lipid Research. 53: 2469-83. PMID 22891291 DOI: 10.1194/Jlr.D028233  0.577
2011 Ribeiro D, Ellwanger K, Glagow D, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C, Arenas E. Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. Plos One. 6: e15786. PMID 21347250 DOI: 10.1371/Journal.Pone.0015786  0.771
2011 Theofilopoulos S, Karu K, Kitambi S, Sacchetti P, Sousa K, Sjovall J, Griffiths W, Arenas E. Identification and characterisation of endogenous LXR ligands in ventral midbrain development Neuroscience Research. 71: e50. DOI: 10.1016/J.Neures.2011.07.211  0.725
2010 Ogundare M, Theofilopoulos S, Lockhart A, Hall LJ, Arenas E, Sjövall J, Brenton AG, Wang Y, Griffiths WJ. Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? The Journal of Biological Chemistry. 285: 4666-79. PMID 19996111 DOI: 10.1074/Jbc.M109.086678  0.535
2009 Sacchetti P, Sousa KM, Hall AC, Liste I, Steffensen KR, Theofilopoulos S, Parish CL, Hazenberg C, Richter LA, Hovatta O, Gustafsson JA, Arenas E. Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell. 5: 409-19. PMID 19796621 DOI: 10.1016/J.Stem.2009.08.019  0.758
2009 Wang Y, Sousa KM, Bodin K, Theofilopoulos S, Sacchetti P, Hornshaw M, Woffendin G, Karu K, Sjövall J, Arenas E, Griffiths WJ. Targeted lipidomic analysis of oxysterols in the embryonic central nervous system. Molecular Biosystems. 5: 529-41. PMID 19381367 DOI: 10.1039/B819502A  0.7
2004 Riaz SS, Theofilopoulos S, Jauniaux E, Stern GM, Bradford HF. The differentiation potential of human foetal neuronal progenitor cells in vitro. Brain Research. Developmental Brain Research. 153: 39-51. PMID 15464216 DOI: 10.1016/J.Devbrainres.2004.07.006  0.528
2001 Theofilopoulos S, Goggi J, Riaz SS, Jauniaux E, Stern GM, Bradford HF. Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain-derived neurotrophic factor and glial-cell derived neurotrophic factor. Brain Research. Developmental Brain Research. 127: 111-22. PMID 11334998 DOI: 10.1016/S0165-3806(01)00125-0  0.421
2000 Goggi J, Theofilopoulos S, Riaz SS, Jauniaux E, Stern GM, Bradford HF. The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture. Neuroreport. 11: 3937-41. PMID 11192605 DOI: 10.1097/00001756-200012180-00007  0.473
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