| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2020 | Kweon HJ, Gu S, Witham E, Dhara M, Yu H, Mandon ED, Jawhari A, Bredt DS. NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly. Cell Reports. 32: 108025. PMID 32783947 DOI: 10.1016/J.Celrep.2020.108025 | 0.547 | |||
| 2020 | Dhara M, Matta JA, Lei M, Knowland D, Yu H, Gu S, Bredt DS. Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. Nature Communications. 11: 2799. PMID 32493979 DOI: 10.1038/S41467-020-16629-3 | 0.539 | |||
| 2019 | Dawe GB, Yu H, Gu S, Blackler AN, Matta JA, Siuda ER, Rex EB, Bredt DS. α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins. Nature Communications. 10: 2746. PMID 31227712 DOI: 10.1038/S41467-019-10723-X | 0.565 | |||
| 2016 | Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, et al. Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine. PMID 27820603 DOI: 10.1038/Nm.4221 | 0.588 | |||
| 2016 | Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, ... ... Yu H, et al. The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry. PMID 27067148 DOI: 10.1021/Acs.Jmedchem.6B00125 | 0.598 | |||
| 2016 | Erlenhardt N, Yu H, Abiraman K, Yamasaki T, Wadiche JI, Tomita S, Bredt DS. Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Reports. PMID 26776514 DOI: 10.1016/J.Celrep.2015.12.078 | 0.568 | |||
| 2011 | Gill MB, Kato AS, Roberts MF, Yu H, Wang H, Tomita S, Bredt DS. Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6928-38. PMID 21543622 DOI: 10.1523/Jneurosci.6271-10.2011 | 0.58 | |||
| 2011 | Schober DA, Gill MB, Yu H, Gernert DL, Jeffries MW, Ornstein PL, Kato AS, Felder CC, Bredt DS. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of Biological Chemistry. 286: 13134-42. PMID 21343286 DOI: 10.1074/Jbc.M110.212522 | 0.597 | |||
| 2010 | Kato AS, Gill MB, Ho MT, Yu H, Tu Y, Siuda ER, Wang H, Qian YW, Nisenbaum ES, Tomita S, Bredt DS. Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron. 68: 1082-96. PMID 21172611 DOI: 10.1016/J.Neuron.2010.11.026 | 0.595 | |||
| 2010 | Kato AS, Gill MB, Yu H, Nisenbaum ES, Bredt DS. TARPs differentially decorate AMPA receptors to specify neuropharmacology. Trends in Neurosciences. 33: 241-8. PMID 20219255 DOI: 10.1016/J.Tins.2010.02.004 | 0.575 | |||
| 2008 | Perry KW, Falcone JF, Fell MJ, Ryder JW, Yu H, Love PL, Katner J, Gordon KD, Wade MR, Man T, Nomikos GG, Phebus LA, Cauvin AJ, Johnson KW, Jones CK, et al. Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas. Neuropharmacology. 55: 743-54. PMID 18602930 DOI: 10.1016/J.Neuropharm.2008.06.016 | 0.347 | |||
| 2007 | Walter MW, Hoffman BJ, Gordon K, Johnson K, Love P, Jones M, Man T, Phebus L, Reel JK, Rudyk HC, Shannon H, Svensson K, Yu H, Valli MJ, Porter WJ. Discovery and SAR studies of novel GlyT1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 5233-8. PMID 17629697 DOI: 10.1016/J.Bmcl.2007.06.074 | 0.692 | |||
| 2007 | Kato AS, Zhou W, Milstein AD, Knierman MD, Siuda ER, Dotzlaf JE, Yu H, Hale JE, Nisenbaum ES, Nicoll RA, Bredt DS. New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4969-77. PMID 17475805 DOI: 10.1523/Jneurosci.5561-06.2007 | 0.586 | |||
| 2003 | Johnson KW, Clemens-Smith A, Nomikos G, Davis R, Phebus L, Shannon H, Love P, Perry K, Katner J, Bymaster F, Yu H, Hoffman BJ. In vivo characterization of changes in glycine levels induced by GlyT1 inhibitors. Annals of the New York Academy of Sciences. 1003: 412-4. PMID 14684475 DOI: 10.1196/Annals.1300.039 | 0.694 | |||
| 2002 | Quirk JC, Linden AM, Strakhova M, Yu H, Skolnick P, Nisenbaum ES. A single residue contributes sensitivity to allosteric modulation of AMPA receptors by LY395153. European Journal of Pharmacology. 454: 125-9. PMID 12421639 DOI: 10.1016/S0014-2999(02)02491-3 | 0.51 | |||
| 2001 | Harvey SC, Köster A, Yu H, Skolnick P, Baumbarger P, Nisenbaum ES. AMPA receptor function is altered in GLUR2-deficient mice. Journal of Molecular Neuroscience : Mn. 17: 35-43. PMID 11665861 DOI: 10.1385/Jmn:17:1:35 | 0.517 | |||
| 2001 | Lindén AM, Yu H, Zarrinmayeh H, Wheeler WJ, Skolnick P. Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors. Neuropharmacology. 40: 1010-8. PMID 11406192 DOI: 10.1016/S0028-3908(01)00013-2 | 0.535 | |||
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