Tom Curran - Publications

Children's Mercy Kansas City 
 1984-1995 Roche Institute of Molecular Biology 
Biology, Cancer Research, Neuroscience

161 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 7. PMID 29360039 DOI: 10.7554/eLife.32586  1
2016 Park T, Koptyra M, Curran T. Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL). The Journal of Biological Chemistry. PMID 27807028 DOI: 10.1074/jbc.M116.764613  1
2015 Ng JM, Martinez D, Marsh ED, Zhang Z, Rappaport E, Santi M, Curran T. Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53. Cancer Research. PMID 26363008 DOI: 10.1158/0008-5472.CAN-15-0874  1
2015 Dang MT, Wehrli S, Dang CV, Curran T. The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice. Plos One. 10: e0133633. PMID 26192445 DOI: 10.1371/journal.pone.0133633  1
2015 Huang Y, Clarke F, Karimi M, Roy NH, Williamson EK, Okumura M, Mochizuki K, Chen EJ, Park TJ, Debes GF, Zhang Y, Curran T, Kambayashi T, Burkhardt JK. CRK proteins selectively regulate T cell migration into inflamed tissues. The Journal of Clinical Investigation. 125: 1019-32. PMID 25621495 DOI: 10.1172/JCI77278  1
2015 Koptyra M, Park TJ, Curran T. Crk and CrkL are required for cell transformation by v-fos and v-ras. Molecular Carcinogenesis. PMID 25557916 DOI: 10.1002/mc.22262  1
2015 Kim J, Park TJ, Kwon N, Lee D, Kim S, Kohmura Y, Ishikawa T, Kim KT, Curran T, Je JH. Dendritic planarity of Purkinje cells is independent of Reelin signaling. Brain Structure & Function. 220: 2263-73. PMID 24828132 DOI: 10.1007/s00429-014-0780-2  1
2014 Park TJ, Curran T. Neurobiology: Reelin mediates form and function. Current Biology : Cb. 24: R1089-92. PMID 25458219 DOI: 10.1016/j.cub.2014.10.012  1
2014 George B, Fan Q, Dlugos CP, Soofi AA, Zhang J, Verma R, Park TJ, Wong H, Curran T, Nihalani D, Holzman LB. Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis. Kidney International. 85: 1382-94. PMID 24499776 DOI: 10.1038/ki.2013.556  1
2013 Gajjar A, Stewart CF, Ellison DW, Kaste S, Kun LE, Packer RJ, Goldman S, Chintagumpala M, Wallace D, Takebe N, Boyett JM, Gilbertson RJ, Curran T. Phase I study of vismodegib in children with recurrent or refractory medulloblastoma: a pediatric brain tumor consortium study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6305-12. PMID 24077351 DOI: 10.1158/1078-0432.CCR-13-1425  1
2013 Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X. Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. Cancer Research. 73: 2650-8. PMID 23580576 DOI: 10.1158/0008-5472.CAN-12-3158  1
2012 Wang Y, Davidow L, Arvanites AC, Blanchard J, Lam K, Xu K, Oza V, Yoo JW, Ng JM, Curran T, Rubin LL, McMahon AP. Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity. Chemistry & Biology. 19: 972-82. PMID 22921064 DOI: 10.1016/j.chembiol.2012.06.012  1
2012 George B, Verma R, Soofi AA, Garg P, Zhang J, Park TJ, Giardino L, Ryzhova L, Johnstone DB, Wong H, Nihalani D, Salant DJ, Hanks SK, Curran T, Rastaldi MP, et al. Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. The Journal of Clinical Investigation. 122: 674-92. PMID 22251701 DOI: 10.1172/JCI60070  1
2012 Austgen K, Johnson ET, Park TJ, Curran T, Oakes SA. The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress. Nature Cell Biology. 14: 87-92. PMID 22179045 DOI: 10.1038/ncb2395  1
2011 Ng JM, Curran T. The Hedgehog's tale: developing strategies for targeting cancer. Nature Reviews. Cancer. 11: 493-501. PMID 21614026 DOI: 10.1038/nrc3079  1
2011 Brechbiel JL, Ng JM, Curran T. PTHrP treatment fails to rescue bone defects caused by Hedgehog pathway inhibition in young mice. Toxicologic Pathology. 39: 478-85. PMID 21411723 DOI: 10.1177/0192623311399788  1
2011 Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, ... ... Curran T, et al. The genetic landscape of the childhood cancer medulloblastoma. Science (New York, N.Y.). 331: 435-9. PMID 21163964 DOI: 10.1126/science.1198056  1
2010 Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD. Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (Cambridge, England). 137: 3753-61. PMID 20978073 DOI: 10.1242/dev.056358  1
2010 Curran T. Mouse models and mouse supermodels. Embo Molecular Medicine. 2: 385-6; author reply . PMID 20721989 DOI: 10.1002/emmm.201000090  1
2010 Park TJ, Curran T. Alternative splicing disabled by Nova2. Neuron. 66: 811-3. PMID 20620865 DOI: 10.1016/j.neuron.2010.06.012  1
2009 Ng L, Ma M, Curran T, Forrest D. Developmental expression of thyroid hormone receptor beta2 protein in cone photoreceptors in the mouse. Neuroreport. 20: 627-31. PMID 19282790 DOI: 10.1097/WNR.0b013e32832a2c63  1
2008 Park TJ, Curran T. Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13551-62. PMID 19074029 DOI: 10.1523/JNEUROSCI.4323-08.2008  1
2008 Curran T, Ng JM. Cancer: Hedgehog's other great trick. Nature. 455: 293-4. PMID 18800119 DOI: 10.1038/455293a  1
2008 De Gasperi R, Gama Sosa MA, Wen PH, Li J, Perez GM, Curran T, Elder GA. Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2405-14. PMID 18729224 DOI: 10.1002/dvdy.21661  1
2007 Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS. Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Molecular and Cellular Biology. 27: 6706-17. PMID 17646384 DOI: 10.1128/MCB.01225-07  1
2007 Sasai K, Romer JT, Kimura H, Eberhart DE, Rice DS, Curran T. Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor. Cancer Research. 67: 3871-7. PMID 17413002 DOI: 10.1158/0008-5472.CAN-07-0493  1
2006 Park TJ, Boyd K, Curran T. Cardiovascular and craniofacial defects in Crk-null mice. Molecular and Cellular Biology. 26: 6272-82. PMID 16880535 DOI: 10.1128/MCB.00472-06  1
2006 Lee Y, Miller HL, Russell HR, Boyd K, Curran T, McKinnon PJ. Patched2 modulates tumorigenesis in patched1 heterozygous mice. Cancer Research. 66: 6964-71. PMID 16849540 DOI: 10.1158/0008-5472.CAN-06-0505  1
2006 Dellovade T, Romer JT, Curran T, Rubin LL. The hedgehog pathway and neurological disorders. Annual Review of Neuroscience. 29: 539-63. PMID 16776596 DOI: 10.1146/annurev.neuro.29.051605.112858  1
2006 Brumwell CL, Curran T. Developmental mouse brain gene expression maps. The Journal of Physiology. 575: 343-6. PMID 16728446 DOI: 10.1113/jphysiol.2006.112607  1
2006 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, ... Curran T, et al. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Plos Biology. 4: e86. PMID 16602821 DOI: 10.1371/journal.pbio.0040086  1
2005 Uziel T, Zindy F, Xie S, Lee Y, Forget A, Magdaleno S, Rehg JE, Calabrese C, Solecki D, Eberhart CG, Sherr SE, Plimmer S, Clifford SC, Hatten ME, McKinnon PJ, ... ... Curran T, et al. The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes & Development. 19: 2656-67. PMID 16260494 DOI: 10.1101/gad.1368605  1
2005 Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, et al. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell. 8: 323-35. PMID 16226707 DOI: 10.1016/j.ccr.2005.09.001  1
2005 Curran T. Lost in translation: the future of cancer research? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4644-5. PMID 16000555 DOI: 10.1158/1078-0432.CCR-05-0333  1
2005 Romer J, Curran T. Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics. Cancer Research. 65: 4975-8. PMID 15958535 DOI: 10.1158/0008-5472.CAN-05-0481  1
2005 Ordway JM, Fenster SD, Ruan H, Curran T. A transcriptome map of cellular transformation by the fos oncogene. Molecular Cancer. 4: 19. PMID 15918904 DOI: 10.1186/1476-4598-4-19  1
2005 Kimura H, Stephen D, Joyner A, Curran T. Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene. 24: 4026-36. PMID 15806168 DOI: 10.1038/sj.onc.1208567  1
2004 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T. A neurogenomics approach to gene expression analysis in the developing brain. Brain Research. Molecular Brain Research. 132: 116-27. PMID 15582152 DOI: 10.1016/j.molbrainres.2004.10.002  1
2004 Romer JT, Kimura H, Magdaleno S, Sasai K, Fuller C, Baines H, Connelly M, Stewart CF, Gould S, Rubin LL, Curran T. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell. 6: 229-40. PMID 15380514 DOI: 10.1016/j.ccr.2004.08.019  1
2004 Ordway JM, Williams K, Curran T. Transcription repression in oncogenic transformation: common targets of epigenetic repression in cells transformed by Fos, Ras or Dnmt1. Oncogene. 23: 3737-48. PMID 14990994 DOI: 10.1038/sj.onc.1207483  1
2003 Curran T. From bings to biology: taking a different path in cancer research. Cancer Biology & Therapy. 2: 456-9. PMID 14508121 DOI: 10.4161/cbt.2.4.449  1
2003 Lee Y, Miller HL, Jensen P, Hernan R, Connelly M, Wetmore C, Zindy F, Roussel MF, Curran T, Gilbertson RJ, McKinnon PJ. A molecular fingerprint for medulloblastoma. Cancer Research. 63: 5428-37. PMID 14500378  1
2003 Homayouni R, Magdaleno S, Keshvara L, Rice DS, Curran T. Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain. Brain Research. Molecular Brain Research. 115: 121-9. PMID 12877983 DOI: 10.1016/S0169-328X(03)00176-1  1
2003 Li L, Connelly MC, Wetmore C, Curran T, Morgan JI. Mouse embryos cloned from brain tumors. Cancer Research. 63: 2733-6. PMID 12782575  1
2003 Ordway JM, Eberhart D, Curran T. Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding. Molecular and Cellular Biology. 23: 4257-66. PMID 12773568  1
2002 Gilbertson RJ, Bentley L, Hernan R, Junttila TT, Frank AJ, Haapasalo H, Connelly M, Wetmore C, Curran T, Elenius K, Ellison DW. ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3054-64. PMID 12374672  1
2002 Ordway JM, Curran T. Methylation matters: modeling a manageable genome. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 149-62. PMID 11971815  1
2002 Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 415: 436-42. PMID 11807556 DOI: 10.1038/415436a  1
1999 Bakin AV, Curran T. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science (New York, N.Y.). 283: 387-90. PMID 9888853 DOI: 10.1126/science.283.5400.387  1
1998 Curran T. c-fos and Signal Transduction In Vivo. Toxicology in Vitro : An International Journal Published in Association With Bibra. 12: 523-4. PMID 20654433 DOI: 10.1016/S0887-2333(98)00028-9  1
1998 Vendrell M, Curran T, Morgan JI. A gene expression approach to mapping the functional maturation of the hippocampus. Brain Research. Molecular Brain Research. 63: 25-34. PMID 9838029 DOI: 10.1016/S0169-328X(98)00248-4  1
1997 Kerppola TK, Curran T. The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. The Embo Journal. 16: 2907-16. PMID 9184234 DOI: 10.1093/emboj/16.10.2907  1
1996 Ito K, Asano M, Hughes P, Kohzaki H, Masutani C, Hanaoka F, Kerppola T, Curran T, Murakami Y, Ito Y. c-Jun stimulates origin-dependent DNA unwinding by polyomavirus large Tantigen. The Embo Journal. 15: 5636-46. PMID 8896457  1
1996 Kasof GM, Smeyne RJ, Curran T, Morgan JI. Developmental expression of Fos-lacZ in the brains of postnatal transgenic rats. Brain Research. Developmental Brain Research. 93: 191-7. PMID 8804706 DOI: 10.1016/0165-3806(96)00005-3  1
1996 Xanthoudakis S, Smeyne RJ, Wallace JD, Curran T. The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 8919-23. PMID 8799128 DOI: 10.1073/pnas.93.17.8919  1
1996 Martin ML, Lieberman PM, Curran T. Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF. Molecular and Cellular Biology. 16: 2110-8. PMID 8628277  1
1996 Chen RH, Juo PC, Curran T, Blenis J. Phosphorylation of c-Fos at the C-terminus enhances its transforming activity. Oncogene. 12: 1493-502. PMID 8622865  1
1996 Hermida-Matsumoto ML, Chock PB, Curran T, Yang DC. Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes. The Journal of Biological Chemistry. 271: 4930-6. PMID 8617766  0.01
1995 Kasof GM, Mahanty NK, Pozzo Miller LD, Curran T, Connor JA, Morgan JI. Spontaneous and evoked glutamate signalling influences Fos-lacZ expression and pyramidal cell death in hippocampal slice cultures from transgenic rats. Brain Research. Molecular Brain Research. 34: 197-208. PMID 8750823 DOI: 10.1016/0169-328X(95)00158-O  1
1995 Robertson LM, Kerppola TK, Vendrell M, Luk D, Smeyne RJ, Bocchiaro C, Morgan JI, Curran T. Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron. 14: 241-52. PMID 7857636 DOI: 10.1016/0896-6273(95)90282-1  0.01
1995 Kerppola T, Curran T. Zen and the art of Fos and Jun Nature. 373: 199-200. PMID 7816132  1
1995 Kasof GM, Mandelzys A, Maika SD, Hammer RE, Curran T, Morgan JI. Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4238-49. PMID 7790908  1
1995 Curran T, Morgan JI. Fos: an immediate-early transcription factor in neurons. Journal of Neurobiology. 26: 403-12. PMID 7775973 DOI: 10.1002/neu.480260312  1
1995 D'Arcangelo G, Miao GG, Chen SC, Soares HD, Morgan JI, Curran T. A protein related to extracellular matrix proteins deleted in the mouse mutant reeler. Nature. 374: 719-23. PMID 7715726 DOI: 10.1038/374719a0  1
1995 Chen SC, Curran T, Morgan JI. Apoptosis in the nervous system: new revelations. Journal of Clinical Pathology. 48: 7-12. PMID 7706524  1
1995 Morgan JI, Curran T. Immediate-early genes: ten years on. Trends in Neurosciences. 18: 66-7. PMID 7537412 DOI: 10.1016/0166-2236(95)80022-T  1
1995 Ng L, Forrest D, Haugen BR, Wood WM, Curran T. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone. Molecular Endocrinology (Baltimore, Md.). 9: 1202-13. PMID 7491112 DOI: 10.1210/mend.9.9.7491112  1
1994 Hsu W, Kerppola TK, Chen PL, Curran T, Chen-Kiang S. Fos and jun repress transcription activation by NF-IL6 through association at the basic zipper region Molecular and Cellular Biology. 14: 268-276. PMID 8264594  1
1994 Miao GG, Curran T. Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle Molecular and Cellular Biology. 14: 4295-4310. PMID 8196666  1
1994 Kerppola TK, Curran T. Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun Oncogene. 9: 675-684. PMID 8108109  1
1994 Yao KS, Xanthoudakis S, Curran T, O'Dwyer PJ. Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. Molecular and Cellular Biology. 14: 5997-6003. PMID 8065332  1
1994 Forrest D, Yuzaki M, Soares HD, Ng L, Luk DC, Sheng M, Stewart CL, Morgan JI, Connor JA, Curran T. Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron. 13: 325-38. PMID 8060614 DOI: 10.1016/0896-6273(94)90350-6  1
1994 Patel LR, Curran T, Kerppola TK. Energy transfer analysis of fos-jun dimerization and DNA binding Proceedings of the National Academy of Sciences of the United States of America. 91: 7360-7364. PMID 8041795 DOI: 10.1073/pnas.91.15.7360  1
1994 Miao GG, Smeyne RJ, D'Arcangelo G, Copeland NG, Jenkins NA, Morgan JI, Curran T. Isolation of an allele of reeler by insertional mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 91: 11050-4. PMID 7972007 DOI: 10.1073/pnas.91.23.11050  1
1994 Kerppola TK, Curran T. A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins Oncogene. 9: 3149-3158. PMID 7936637  1
1994 Yaseen NR, Park J, Kerppola T, Curran T, Sharma S. A central role for Fos in human B- and T-cell NFAT (nuclear factor of activated T cells): an acidic region is required for in vitro assembly. Molecular and Cellular Biology. 14: 6886-95. PMID 7935406  1
1994 Xanthoudakis S, Curran T. Analysis of c-fos and c-jun redox-dependent DNA binding activity Methods in Enzymology. 234: 163-174. PMID 7808290 DOI: 10.1016/0076-6879(94)34086-2  1
1994 Soares HD, Curran T, Morgan JI. Transcription factors as molecular mediators in cell death. Annals of the New York Academy of Sciences. 747: 172-82. PMID 7531406  1
1994 Xanthoudakis S, Miao GG, Curran T. The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains Proceedings of the National Academy of Sciences of the United States of America. 91: 23-27. PMID 7506414 DOI: 10.1073/pnas.91.1.23  1
1993 Kerppola TK, Luk D, Curran T. Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro Molecular and Cellular Biology. 13: 3782-3791. PMID 8497279  1
1993 Molinar-Rode R, Smeyne RJ, Curran T, Morgan JI. Regulation of proto-oncogene expression in adult and developing lungs. Molecular and Cellular Biology. 13: 3213-20. PMID 8497249  1
1993 Smeyne RJ, Vendrell M, Hayward M, Baker SJ, Miao GG, Schilling K, Robertson LM, Curran T, Morgan JI. Continuous c-fos expression precedes programmed cell death in vivo. Nature. 363: 166-9. PMID 8483500 DOI: 10.1038/363166a0  1
1993 Okuno H, Akahori A, Sato H, Xanthoudakis S, Curran T, Iba H. Escape from redox regulation enhances the transforming activity of Fos. Oncogene. 8: 695-701. PMID 8437852  1
1993 Smeyne RJ, Schilling K, Oberdick J, Robertson L, Luk D, Curran T, Morgan JI. A fos-lac Z transgenic mouse that can be used for neuroanatomic mapping. Advances in Neurology. 59: 285-91. PMID 8420113  1
1993 Curran T, Abate C, Baker S, Kerppola T, Xanthoudakis S. The regulation of c-fos: too much is never enough. Advances in Second Messenger and Phosphoprotein Research. 28: 271-7. PMID 8398414  1
1993 Jain J, McCaffrey PG, Miner Z, Kerppola TK, Lambert JN, Verdine GL, Curran T, Rao A. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature. 365: 352-5. PMID 8397339 DOI: 10.1038/365352a0  1
1993 Kerppola TK, Curran T. Selective DNA bending by a variety of bZIP proteins Molecular and Cellular Biology. 13: 5479-5489. PMID 8355695  1
1993 Abate C, Baker SJ, Lees-Miller SP, Anderson CW, Marshak DR, Curran T. Dimerization and DNA binding alter phosphorylation of Fos and Jun. Proceedings of the National Academy of Sciences of the United States of America. 90: 6766-70. PMID 8341696  1
1993 Ng L, Forrest D, Curran T. Differential roles for fos and jun in DNA-binding: Redoxdependent and independent functions Nucleic Acids Research. 21: 5831-5837. PMID 8290340 DOI: 10.1093/nar/21.25.5831  1
1993 McCaffrey PG, Luo C, Kerppola TK, Jain J, Badalian TM, Ho AM, Burgeon E, Lane WS, Lambert JN, Curran T, Verdine GL, Rao A, Hogan PG. Isolation of the cyclosporin-sensitive T cell transcription factor NFATp Science. 262: 750-754. PMID 8235597  1
1993 Vendrell M, Curran T, Morgan JI. Glutamate, immediate-early genes, and cell death in the nervous system. Annals of the New York Academy of Sciences. 679: 132-41. PMID 8099770  1
1992 Smeyne RJ, Schilling K, Robertson L, Luk D, Oberdick J, Curran T, Morgan JI. fos-lacZ transgenic mice: mapping sites of gene induction in the central nervous system. Neuron. 8: 13-23. PMID 1730004 DOI: 10.1016/0896-6273(92)90105-M  1
1992 Forrest D, Curran T. Crossed signals: oncogenic transcription factors Current Opinion in Genetics and Development. 2: 19-27. PMID 1633422 DOI: 10.1016/S0959-437X(05)80316-8  1
1992 Xanthoudakis S, Curran T. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity Embo Journal. 11: 653-665. PMID 1537340  1
1992 Xanthoudakis S, Miao G, Wang F, Pan YC, Curran T. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. The Embo Journal. 11: 3323-35. PMID 1380454  1
1992 Smeyne RJ, Curran T, Morgan JI. Temporal and spatial expression of a fos-lacZ transgene in the developing nervous system. Brain Research. Molecular Brain Research. 16: 158-62. PMID 1334194 DOI: 10.1016/0169-328X(92)90206-Q  1
1992 Baker SJ, Kerppola TK, Luk D, Vandenberg MT, Marshak DR, Curran T, Abate C. Jun Is Phosphorylated by Several Protein Kinases at the Same Sites That Are Modified in Serum-Stimulated Fibroblasts Molecular and Cellular Biology. 12: 4694-4705. PMID 1328860  1
1992 Curran T. Fos and Jun: oncogenic transcription factors Tohoku Journal of Experimental Medicine. 168: 169-174. PMID 1306301  1
1991 Kerppola TK, Curran T. DNA bending by Fos and Jun: The flexible hinge model Science. 254: 1210-1214. PMID 1957173  1
1991 Morgan JI, Curran T. Proto-oncogene transcription factors and epilepsy. Trends in Pharmacological Sciences. 12: 343-9. PMID 1949203 DOI: 10.1016/0165-6147(91)90594-I  1
1991 Okuno H, Suzuki T, Yoshida T, Hashimoto Y, Curran T, Iba H. Inhibition of jun transformation by a mutated fos gene: design of an anti-oncogene. Oncogene. 6: 1491-7. PMID 1923517  1
1991 Schilling K, Curran T, Morgan JI. Fosvergnügen. The excitement of immediate-early genes. Annals of the New York Academy of Sciences. 627: 115-23. PMID 1909106  1
1991 Kerppola TK, Curran T. Fos-Jun heterodimers and jun homodimers bend DNA in opposite orientations: Implications for transcription factor cooperativity Cell. 66: 317-326. PMID 1906785 DOI: 10.1016/0092-8674(91)90621-5  1
1991 Abate C, Luk D, Curran T. Transcriptional regulation by Fos and Jun in vitro: Interaction among multiple activator and regulatory domains Molecular and Cellular Biology. 11: 3624-3632. PMID 1904542  1
1991 Morgan JI, Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annual Review of Neuroscience. 14: 421-51. PMID 1903243 DOI: 10.1146/  1
1991 Hai T, Curran T. Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity Proceedings of the National Academy of Sciences of the United States of America. 88: 3720-3724. PMID 1827203  1
1991 Abate C, Marshak DR, Curran T. Fos is phosphorylated by p34cdc2, cAMP-dependent protein kinase and protein kinase C at multiple sites clustered within regulatory regions Oncogene. 6: 2179-2185. PMID 1766667  1
1991 Schilling K, Luk D, Morgan JI, Curran T. Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling. Proceedings of the National Academy of Sciences of the United States of America. 88: 5665-9. PMID 1648227  1
1990 Macgregor PF, Abate C, Curran T. Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1. Oncogene. 5: 451-8. PMID 2139203  1
1990 Abate C, Curran T. Encounters with Fos and Jun on the road to AP-1 Seminars in Cancer Biology. 1: 19-26. PMID 2133107  1
1990 Curran T, Abate C, Cohen DR, Macgregor PF, Rauscher FJ, Sonnenberg JL, Connor JA, Morgan JI. Inducible proto-oncogene transcription factors: third messengers in the brain? Cold Spring Harbor Symposia On Quantitative Biology. 55: 225-34. PMID 2132816  1
1990 Morgan JI, Curran T. Inducible proto-oncogenes of the nervous system: their contribution to transcription factors and neuroplasticity. Progress in Brain Research. 86: 287-94. PMID 2128418  1
1990 Abate C, Luk D, Curran T. A ubiquitous nuclear protein stimulates the DNA-binding activity of fos and jun indirectly. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 1: 455-62. PMID 2126189  1
1990 Patel L, Abate C, Curran T. Altered protein conformation on DNA binding by Fos and Jun Nature. 347: 572-575. PMID 2120592  1
1990 Abate C, Luk D, Gagne E, Roeder RG, Curran T. Fos and jun cooperate in transcriptional regulation via heterologous activation domains. Molecular and Cellular Biology. 10: 5532-5. PMID 2119000  1
1990 Abate C, Patel L, Rauscher FJ, Curran T. Redox regulation of Fos and Jun DNA-binding activity in vitro Science. 249: 1157-1161. PMID 2118682  1
1990 Shin C, McNamara JO, Morgan JI, Curran T, Cohen DR. Induction of c-fos mRNA expression by afterdischarge in the hippocampus of naive and kindled rats. Journal of Neurochemistry. 55: 1050-5. PMID 2117045  1
1990 Gius D, Cao XM, Rauscher FJ, Cohen DR, Curran T, Sukhatme VP. Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements. Molecular and Cellular Biology. 10: 4243-55. PMID 2115122  1
1990 Cohen DR, Curran T. Analysis of dimerization and DNA binding functions in Fos and Jun by domain-swapping: involvement of residues outside the leucine zipper/basic region. Oncogene. 5: 929-39. PMID 2113670  1
1990 Abate C, Luk D, Gentz R, Rauscher FJ, Curran T. Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: Both Fos and Jun contact DNA directly Proceedings of the National Academy of Sciences of the United States of America. 87: 1032-1036. PMID 2105492  1
1989 Mugnaini E, Berrebi AS, Morgan JI, Curran T. Fos-Like Immunoreactivity Induced by Seizure in Mice Is Specifically Associated With Euchromatin in Neurons. The European Journal of Neuroscience. 1: 46-52. PMID 12106173  1
1989 Sonnenberg JL, Mitchelmore C, Macgregor-Leon PF, Hempstead J, Morgan JI, Curran T. Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain. Journal of Neuroscience Research. 24: 72-80. PMID 2553994 DOI: 10.1002/jnr.490240111  1
1989 Cohen DR, Curran T. The structure and function of the fos proto-oncogene. Critical Reviews in Oncogenesis. 1: 65-88. PMID 2518683  1
1989 Morgan JI, Curran T. Calcium and proto-oncogene involvement in the immediate-early response in the nervous system. Annals of the New York Academy of Sciences. 568: 283-90. PMID 2516994 DOI: 10.1111/j.1749-6632.1989.tb12518.x  1
1989 Sonnenberg JL, Rauscher FJ, Morgan JI, Curran T. Regulation of proenkephalin by Fos and Jun. Science (New York, N.Y.). 246: 1622-5. PMID 2512642  1
1989 Cohen DR, Ferreira PC, Gentz R, Franza BR, Curran T. The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes. Genes & Development. 3: 173-84. PMID 2497053  1
1989 Gentz R, Rauscher FJ, Abate C, Curran T. Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains Science. 243: 1695-1699. PMID 2494702  1
1989 Bos TJ, Rauscher FJ, Curran T, Vogt PK. The carboxy terminus of the viral Jun oncoprotein is required for complex formation with the cellular Fos protein Oncogene. 4: 123-126. PMID 2494630  1
1989 Morgan JI, Curran T. Stimulus-transcription coupling in neurons: role of cellular immediate-early genes. Trends in Neurosciences. 12: 459-62. PMID 2479148 DOI: 10.1016/0166-2236(89)90096-9  1
1988 Lee WM, Lin C, Curran T. Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos protein. Molecular and Cellular Biology. 8: 5521-7. PMID 3149716  0.01
1988 Morgan JI, Curran T. Calcium as a modulator of the immediate-early gene cascade in neurons. Cell Calcium. 9: 303-11. PMID 3147142 DOI: 10.1016/0143-4160(88)90011-5  1
1988 Curran T, Franza BR. Fos and jun: The AP-1 connection Cell. 55: 395-397. PMID 3141060  1
1988 Cohen DR, Curran T. fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen. Molecular and Cellular Biology. 8: 2063-9. PMID 3133553  1
1988 Sagar SM, Sharp FR, Curran T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science (New York, N.Y.). 240: 1328-31. PMID 3131879  1
1988 Rauscher FJ, Cohen DR, Curran T, Bos TJ, Vogt PK, Bohmann D, Tjian R, Franza BR. Fos-associated protein p39 is the product of the jun proto-oncogene. Science (New York, N.Y.). 240: 1010-6. PMID 3130660  1
1988 Sukhatme VP, Cao XM, Chang LC, Tsai-Morris CH, Stamenkovich D, Ferreira PC, Cohen DR, Edwards SA, Shows TB, Curran T. A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell. 53: 37-43. PMID 3127059  1
1988 Rauscher FJ, Sambucetti LC, Curran T, Distel RJ, Spiegelman BM. Common DNA binding site for Fos protein complexesand transcription factor AP-1 Cell. 52: 471-480. PMID 3125983 DOI: 10.1016/S0092-8674(88)80039-4  1
1988 Curran T, Rauscher FJ, Cohen DR, Franza BR. Beyond the second messenger: oncogenes and transcription factors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 769-77. PMID 3076095  1
1988 Franza BR, Rauscher FJ, Josephs SF, Curran T. The fos complex and fos-related antigens recognize sequence elements that contain AP-1 binding sites Science. 239: 1150-1153. PMID 2964084  1
1988 Rauscher FJ, Voulalas PJ, Franza BR, Curran T. Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro Genes &Amp; Development. 2: 1687-1699. PMID 2467839  1
1987 O'Hara BM, Klinger HP, Curran T, Zhang YD, Blair DG. Levels of fos, ets2, and myb proto-oncogene RNAs correlate with segregation of chromosome 11 of normal cells and with suppression of tumorigenicity in human cell hybrids. Molecular and Cellular Biology. 7: 2941-6. PMID 3670301  0.01
1987 Curran T, Gordon MB, Rubino KL, Sambucetti LC. Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro. Oncogene. 2: 79-84. PMID 3325886  1
1987 Franza BR, Sambucetti LC, Cohen DR, Curran T. Analysis of Fos protein complexes and Fos-related antigens by high-resolution two-dimensional gel electrophoresis. Oncogene. 1: 213-21. PMID 3325882  1
1987 Curran T, Morgan JI. Memories of fos. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 7: 255-8. PMID 3124834 DOI: 10.1002/bies.950070606  1
1987 Pompidou A, Corral M, Michel P, Defer N, Kruh J, Curran T. The effects of phorbol ester and Ca ionophore on c-fos and c-myc expression and on DNA synthesis in human lymphocytes are not directly related. Biochemical and Biophysical Research Communications. 148: 435-42. PMID 3118872  0.01
1987 Stacey DW, Watson T, Kung HF, Curran T. Microinjection of transforming ras protein induces c-fos expression. Molecular and Cellular Biology. 7: 523-7. PMID 3104768  0.01
1987 Morgan JI, Cohen DR, Hempstead JL, Curran T. Mapping patterns of c-fos expression in the central nervous system after seizure. Science (New York, N.Y.). 237: 192-7. PMID 3037702  1
1986 Sambucetti LC, Curran T. The Fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose Science. 234: 1417-1419. PMID 3491427  1
1986 Curran T, Morgan JI. Barium modulates c-fos expression and post-translational modification. Proceedings of the National Academy of Sciences of the United States of America. 83: 8521-4. PMID 2430291  1
1985 Curran T, Bravo R, Müller R. Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation. Cancer Surveys. 4: 655-81. PMID 3939686  1
1985 Curran T, Van Beveren C, Verma IM. Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein. Molecular and Cellular Biology. 5: 167-72. PMID 3885008  1
1985 Meijlink F, Curran T, Miller AD, Verma IM. Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene. Proceedings of the National Academy of Sciences of the United States of America. 82: 4987-91. PMID 2991903 DOI: 10.1073/pnas.82.15.4987  1
1985 Miller AD, Verma IM, Curran T. Deletion of the gag region from FBR murine osteosarcoma virus does not affect its enhanced transforming activity Journal of Virology. 55: 521-526. PMID 2991577  1
1984 Dusty Miller A, Curran T, Verma IM. c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene Cell. 36: 51-60. PMID 6607118 DOI: 10.1016/0092-8674(84)90073-4  1
1984 Curran T, Miller AD, Zokas L, Verma IM. Viral and cellular fos proteins: a comparative analysis. Cell. 36: 259-68. PMID 6319013  1
1984 Van Beveren C, Enami S, Curran T, Verma IM. FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences acquired from two cellular genes. Virology. 135: 229-43. PMID 6203215  1
1984 Curran T, Verma IM. FBR murine osteosarcoma virus I. Molecular analysis and characterization of a 75,000-Da gag-fos fusion product Virology. 135: 218-228. PMID 6203214 DOI: 10.1016/0042-6822(84)90132-6  1
1983 van Straaten F, Müller R, Curran T, Van Beveren C, Verma IM. Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein. Proceedings of the National Academy of Sciences of the United States of America. 80: 3183-7. PMID 6574479 DOI: 10.1073/pnas.80.11.3183  1
1983 Curran T, MacConnell WP, van Straaten F, Verma IM. Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells. Molecular and Cellular Biology. 3: 914-21. PMID 6306448  1
1983 Van Beveren C, van Straaten F, Curran T, Müller R, Verma IM. Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini. Cell. 32: 1241-55. PMID 6301687  1
1982 Curran T, Peters G, Van Beveren C, Teich NM, Verma IM. FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. Journal of Virology. 44: 674-82. PMID 6292525  1
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