| Year |
Citation |
Score |
| 2017 |
Murone M, Radpour R, Attinger A, Vaslin Chessex A, Huguenin AL, Schürch CM, Banz Y, Sengupta S, Aguet M, Rigotti S, Bachhav Y, Massiere F, Ramachandra M, McAllister A, Riether C. The multi-kinase inhibitor Debio 0617B reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells. Molecular Cancer Therapeutics. PMID 28468777 DOI: 10.1158/1535-7163.Mct-16-0889 |
0.303 |
|
| 2016 |
Cironi L, Petricevic T, Fernandes Vieira V, Provero P, Fusco C, Cornaz S, Fregni G, Letovanec I, Aguet M, Stamenkovic I. The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma. Scientific Reports. 6: 22113. PMID 26905812 DOI: 10.1038/Srep22113 |
0.314 |
|
| 2013 |
Cantù C, Valenta T, Hausmann G, Vilain N, Aguet M, Basler K. The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development (Cambridge, England). 140: 2377-86. PMID 23637336 DOI: 10.1242/Dev.093591 |
0.303 |
|
| 2011 |
Valenta T, Gay M, Steiner S, Draganova K, Zemke M, Hoffmans R, Cinelli P, Aguet M, Sommer L, Basler K. Probing transcription-specific outputs of β-catenin in vivo. Genes & Development. 25: 2631-43. PMID 22190459 DOI: 10.1101/Gad.181289.111 |
0.332 |
|
| 2010 |
Deka J, Wiedemann N, Anderle P, Murphy-Seiler F, Bultinck J, Eyckerman S, Stehle JC, André S, Vilain N, Zilian O, Robine S, Delorenzi M, Basler K, Aguet M. Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. Cancer Research. 70: 6619-28. PMID 20682801 DOI: 10.1158/0008-5472.Can-10-0148 |
0.336 |
|
| 2009 |
Brack AS, Murphy-Seiler F, Hanifi J, Deka J, Eyckerman S, Keller C, Aguet M, Rando TA. BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration. Developmental Biology. 335: 93-105. PMID 19699733 DOI: 10.1016/J.Ydbio.2009.08.014 |
0.3 |
|
| 2007 |
Wilson A, Ardiet DL, Saner C, Vilain N, Beermann F, Aguet M, Macdonald HR, Zilian O. Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike. Journal of Immunology (Baltimore, Md. : 1950). 178: 6746-51. PMID 17513721 DOI: 10.4049/Jimmunol.178.11.6746 |
0.332 |
|
| 2001 |
Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, Miele L, Aguet M, Radtke F, Dotto GP. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. The Embo Journal. 20: 3427-36. PMID 11432830 DOI: 10.1093/Emboj/20.13.3427 |
0.313 |
|
| 2001 |
Zilian O, Saner C, Hagedorn L, Lee HY, Säuberli E, Suter U, Sommer L, Aguet M. Multiple roles of mouse Numb in tuning developmental cell fates. Current Biology : Cb. 11: 494-501. PMID 11412999 DOI: 10.1016/S0960-9822(01)00149-X |
0.315 |
|
| 2000 |
Radtke F, Ferrero I, Wilson A, Lees R, Aguet M, MacDonald HR. Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. The Journal of Experimental Medicine. 191: 1085-94. PMID 10748227 DOI: 10.1084/Jem.191.7.1085 |
0.342 |
|
| 1999 |
Radtke F, Wilson A, Stark G, Bauer M, Meerwijk Jv, MacDonald HR, Aguet M. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity. 10: 547-558. PMID 10367900 DOI: 10.1016/S1074-7613(00)80054-0 |
0.388 |
|
| 1998 |
Kaplan DH, Shankaran V, Dighe AS, Stockert E, Aguet M, Old LJ, Schreiber RD. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 7556-61. PMID 9636188 DOI: 10.1073/Pnas.95.13.7556 |
0.399 |
|
| 1998 |
Spencer SD, Di Marco F, Hooley J, Pitts-Meek S, Bauer M, Ryan AM, Sordat B, Gibbs VC, Aguet M. The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor Journal of Experimental Medicine. 187: 571-578. PMID 9463407 DOI: 10.1084/Jem.187.4.571 |
0.377 |
|
| 1997 |
Wang B, André I, Gonzalez A, Katz JD, Aguet M, Benoist C, Mathis D. Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 94: 13844-9. PMID 9391115 DOI: 10.1073/Pnas.94.25.13844 |
0.336 |
|
| 1997 |
Bach EA, Aguet M, Schreiber RD. The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annual Review of Immunology. 15: 563-91. PMID 9143700 DOI: 10.1146/Annurev.Immunol.15.1.563 |
0.395 |
|
| 1997 |
Merlin G, van der Leede BJ, McKune K, Knezevic N, Bannwarth W, Romquin N, Viegas-Pequignot E, Kiefer H, Aguet M, Dembic Z. The gene for the ligand binding chain of the human interferon gamma receptor. Immunogenetics. 45: 413-21. PMID 9089099 DOI: 10.1007/S002510050223 |
0.318 |
|
| 1996 |
Gibbs VC, Takahashi M, Aguet M, Chuntharapai A. A negative regulatory region in the intracellular domain of the human interferon-alpha receptor. Journal of Biological Chemistry. 271: 28710-28716. PMID 8910507 DOI: 10.1074/Jbc.271.45.28710 |
0.398 |
|
| 1996 |
Eugster HP, Muller M, Karrer U, Car BD, Schnyder B, Eng VM, Woerly G, Le Hir M, di Padova F, Aguet M, Zinkernagel R, Bluethmann H, Ryffel B. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. International Immunology. 8: 23-36. PMID 8671586 DOI: 10.1093/Intimm/8.1.23 |
0.391 |
|
| 1996 |
Bach EA, Tanner JW, Marsters S, Ashkenazi A, Aguet M, Shaw AS, Schreiber RD. Ligand-induced assembly and activation of the gamma interferon receptor in intact cells. Molecular and Cellular Biology. 16: 3214-21. PMID 8649432 DOI: 10.1128/Mcb.16.6.3214 |
0.413 |
|
| 1996 |
Bridges A, Birch A, Williams G, Aguet M, Schlatter D, Huber W, Garotta G, Robinson JA. Variable region cDNA sequences and characterization of murine anti-human interferon gamma receptor monoclonal antibodies that inhibit receptor binding by interferon gamma. Molecular Immunology. 32: 1329-38. PMID 8643102 DOI: 10.1016/0161-5890(95)00114-X |
0.361 |
|
| 1996 |
Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, Dighe AS, Kaplan DH, Riley JK, Greenlund AC, Campbell D, Carver-Moore K, DuBois RN, Clark R, Aguet M, Schreiber RD. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell. 84: 431-42. PMID 8608597 DOI: 10.1016/S0092-8674(00)81288-X |
0.424 |
|
| 1996 |
Haas C, Ryffel B, Aguet M, Le Hir M. MHC antigens in interferon gamma (IFN gamma) receptor deficient mice: IFN gamma-dependent up-regulation of MHC class II in renal tubules. Kidney International. 48: 1721-7. PMID 8587232 DOI: 10.1038/Ki.1995.470 |
0.396 |
|
| 1995 |
van den Broek MF, Müller U, Huang S, Zinkernagel RM, Aguet M. Immune defence in mice lacking type I and/or type II interferon receptors. Immunological Reviews. 148: 5-18. PMID 8825279 DOI: 10.1111/J.1600-065X.1995.Tb00090.X |
0.43 |
|
| 1995 |
Yang YL, Reis LF, Pavlovic J, Aguzzi A, Schäfer R, Kumar A, Williams BR, Aguet M, Weissmann C. Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase. The Embo Journal. 14: 6095-106. PMID 8557029 DOI: 10.1002/J.1460-2075.1995.Tb00300.X |
0.409 |
|
| 1995 |
Rousseau V, Cremer I, Lauret E, Rivière I, Aguet M, De Maeyer E. Antiviral activity of autocrine interferon-beta requires the presence of a functional interferon type I receptor. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 15: 785-9. PMID 8536106 DOI: 10.1089/Jir.1995.15.785 |
0.37 |
|
| 1995 |
Steinhoff U, Müller U, Schertler A, Hengartner H, Aguet M, Zinkernagel RM. Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice. Journal of Virology. 69: 2153-8. PMID 7884863 DOI: 10.1128/Jvi.69.4.2153-2158.1995 |
0.398 |
|
| 1995 |
Swihart K, Fruth U, Messmer N, Hug K, Behin R, Huang S, Giudice GD, Aguet M, Louis JA. Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response Journal of Experimental Medicine. 181: 961-971. PMID 7869054 DOI: 10.1084/Jem.181.3.961 |
0.445 |
|
| 1995 |
Williams G, Ruegg N, Birch A, Weber C, Hofstädter K, Robinson JA, Aguet M, Garotta G, Schlatter D, Huber W. Dissection of the extracellular human interferon gamma receptor alpha-chain into two immunoglobulin-like domains. Production in an Escherichia coli thioredoxin gene fusion expression system and recognition by neutralizing antibodies. Biochemistry. 34: 1787-97. PMID 7849039 DOI: 10.1021/Bi00005A036 |
0.379 |
|
| 1995 |
Fiette L, Aubert C, Muller U, Huang S, Aguet M, Brahic M, Bureau J-. Theiler"s virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors Journal of Experimental Medicine. 181: 2069-2076. PMID 7759999 DOI: 10.1084/Jem.181.6.2069 |
0.354 |
|
| 1995 |
Eng VM, Car BD, Schnyder B, Lorenz M, Lugli S, Aguet M, Anderson TD, Ryffel B, Quesniaux VF. The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo. The Journal of Experimental Medicine. 181: 1893-8. PMID 7722464 DOI: 10.1084/Jem.181.5.1893 |
0.377 |
|
| 1995 |
Flesch IE, Hess JH, Huang S, Aguet M, Rothe J, Bluethmann H, Kaufmann SH. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha. The Journal of Experimental Medicine. 181: 1615-21. PMID 7722441 DOI: 10.1084/Jem.181.5.1615 |
0.361 |
|
| 1995 |
Kühn R, Schwenk F, Aguet M, Rajewsky K. Inducible gene targeting in mice. Science (New York, N.Y.). 269: 1427-9. PMID 7660125 DOI: 10.1126/Science.7660125 |
0.33 |
|
| 1995 |
Rosat JP, Conceiçao-Silva F, Waanders GA, Beermann F, Wilson A, Owen MJ, Hayday AC, Huang S, Aguet M, MacDonald HR. Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells. Infection and Immunity. 63: 3000-4. PMID 7622222 DOI: 10.1128/Iai.63.8.3000-3004.1995 |
0.382 |
|
| 1995 |
van den Broek MF, Müller U, Huang S, Aguet M, Zinkernagel RM. Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors. Journal of Virology. 69: 4792-6. PMID 7609046 DOI: 10.1128/Jvi.69.8.4792-4796.1995 |
0.422 |
|
| 1995 |
Ruby J, Bluethmann H, Aguet M, Ramshaw IA. CD40 ligand has potent antiviral activity. Nature Medicine. 1: 437-41. PMID 7585091 DOI: 10.1038/Nm0595-437 |
0.354 |
|
| 1995 |
Bach EA, Szabo SJ, Dighe AS, Ashkenazi A, Aguet M, Murphy KM, Schreiber RD. Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets. Science (New York, N.Y.). 270: 1215-8. PMID 7502050 DOI: 10.1126/Science.270.5239.1215 |
0.437 |
|
| 1995 |
Ozmen L, Aguet M, Trinchieri G, Garotta G. The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon Journal of Virology. 69: 8147-8150. PMID 7494339 DOI: 10.1128/Jvi.69.12.8147-8150.1995 |
0.353 |
|
| 1995 |
Saulnier M, Huang S, Aguet M, Ryffel B. Role of interferon-gamma in contact hypersensitivity assessed in interferon-gamma receptor-deficient mice. Toxicology. 102: 301-312. PMID 7482569 DOI: 10.1016/0300-483X(95)03101-K |
0.445 |
|
| 1994 |
Car BD, Eng VM, Schnyder B, Ozmen L, Huang S, Gallay P, Heumann D, Aguet M, Ryffel B. Interferon gamma receptor deficient mice are resistant to endotoxic shock. The Journal of Experimental Medicine. 179: 1437-44. PMID 8163930 DOI: 10.1084/Jem.179.5.1437 |
0.398 |
|
| 1994 |
Hemmi S, Bohni R, Stark G, Marco FD, Aguet M. A novel member of the interferon receptor family complements functionality of the murine interferon γ receptor in human cells Cell. 76: 803-810. PMID 8124717 DOI: 10.1016/0092-8674(94)90355-7 |
0.437 |
|
| 1994 |
Weissmann C, Büeler H, Fischer M, Sailer A, Aguzzi A, Aguet M. PrP-deficient mice are resistant to scrapie. Annals of the New York Academy of Sciences. 724: 235-40. PMID 8030944 DOI: 10.1111/J.1749-6632.1994.Tb38913.X |
0.341 |
|
| 1994 |
Müller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Aguet M. Functional role of type I and type II interferons in antiviral defense. Science (New York, N.Y.). 264: 1918-21. PMID 8009221 DOI: 10.1126/Science.8009221 |
0.419 |
|
| 1994 |
Reis LF, Ruffner H, Stark G, Aguet M, Weissmann C. Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes. The Embo Journal. 13: 4798-806. PMID 7957048 DOI: 10.1002/J.1460-2075.1994.Tb06805.X |
0.417 |
|
| 1994 |
Weissmann C, Büeler H, Fischer M, Sauer A, Aguet M. Susceptibility to scrapie in mice is dependent on PrPC. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 431-3. PMID 7913762 DOI: 10.1098/Rstb.1994.0040 |
0.318 |
|
| 1994 |
Heuchel R, Radtke F, Georgiev O, Stark G, Aguet M, Schaffner W. The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. The Embo Journal. 13: 2870-2875. DOI: 10.1002/J.1460-2075.1994.Tb06581.X |
0.305 |
|
| 1993 |
Huang S, Hendriks W, Althage A, Hemmi S, Bluethmann H, Kamijo R, Vilcek J, Zinkernagel RM, Aguet M. Immune response in mice that lack the interferon-gamma receptor. Science (New York, N.Y.). 259: 1742-5. PMID 8456301 DOI: 10.1126/Science.8456301 |
0.468 |
|
| 1993 |
Weissmann C, Büeler H, Fischer M, Aguet M. Role of the PrP gene in transmissible spongiform encephalopathies. Intervirology. 35: 164-75. PMID 8407244 DOI: 10.1159/000150307 |
0.31 |
|
| 1993 |
Kamijo R, Le J, Shapiro D, Havell EA, Huang S, Aguet M, Bosland M, Vilček J. Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide Journal of Experimental Medicine. 178: 1435-1440. PMID 8376946 DOI: 10.1084/Jem.178.4.1435 |
0.419 |
|
| 1993 |
Kamijo R, Shapiro D, Le J, Huang S, Aguet M, Vilcek J. Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 6626-6630. PMID 8341679 DOI: 10.1073/Pnas.90.14.6626 |
0.424 |
|
| 1993 |
Büeler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, Weissmann C. Mice devoid of PrP are resistant to scrapie. Cell. 73: 1339-47. PMID 8100741 DOI: 10.1016/0092-8674(93)90360-3 |
0.333 |
|
| 1992 |
Hemmi S, Merlin G, Aguet M. Functional characterization of a hybrid human-mouse interferon gamma receptor: evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer. Proceedings of the National Academy of Sciences of the United States of America. 89: 2737-2741. PMID 1532657 DOI: 10.1073/Pnas.89.7.2737 |
0.433 |
|
| 1992 |
Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M, Weissmann C. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature. 356: 577-82. PMID 1373228 DOI: 10.1038/356577A0 |
0.339 |
|
| 1991 |
Aguet M. Molecular cloning of interferon receptors: a short review. British Journal of Haematology. 79: 6-8. PMID 1834158 DOI: 10.1111/J.1365-2141.1991.Tb08109.X |
0.431 |
|
| 1990 |
Fischer T, Rehm A, Aguet M, Pfizenmaier K. Human chromosome 21 is necessary and sufficient to confer human IFN γ responsiveness to somatic cell hybrids expressing the cloned human IFN γ receptor gene Cytokine. 2: 157-161. PMID 2151764 DOI: 10.1016/1043-4666(90)90010-Q |
0.401 |
|
| 1990 |
Aguet M. The interferon-gamma receptor: a comparison with other cytokine receptors. Journal of Interferon Research. 10: 551-558. PMID 1707936 DOI: 10.1089/Jir.1990.10.551 |
0.353 |
|
| 1989 |
Mao C, Aguet M, Merlin G. Molecular Characterization of the Human Interferon-γ Receptor: Analysis of Polymorphism and Glycosylation Journal of Interferon Research. 9: 659-669. PMID 2532662 DOI: 10.1089/Jir.1989.9.659 |
0.322 |
|
| 1989 |
Hemmi S, Peghini P, Metzler M, Merlin G, Dembic Z, Aguet M. Cloning of murine interferon gamma receptor cDNA: expression in human cells mediates high-affinity binding but is not sufficient to confer sensitivity to murine interferon gamma. Proceedings of the National Academy of Sciences of the United States of America. 86: 9901-9905. PMID 2532365 DOI: 10.1073/Pnas.86.24.9901 |
0.439 |
|
| 1988 |
Aguet M, Dembić Z, Merlin G. Molecular cloning and expression of the human interferon-γ receptor Cell. 55: 273-280. PMID 2971451 DOI: 10.1016/0092-8674(88)90050-5 |
0.389 |
|
| 1987 |
Aguet M, Merlin G. Purification of human gamma interferon receptors by sequential affinity chromatography on immobilized monoclonal antireceptor antibodies and human gamma interferon. Journal of Experimental Medicine. 165: 988-999. PMID 2435837 DOI: 10.1084/Jem.165.4.988 |
0.411 |
|
| 1986 |
Pircher H, Groscurth P, Baumhütter S, Aguet M, Zinkernagel RM, Hengartner H. A monoclonal antibody against altered LFA-1 induces proliferation and lymphokine release of cloned T cells. European Journal of Immunology. 16: 172-81. PMID 2420606 DOI: 10.1002/Eji.1830160212 |
0.321 |
|
| 1986 |
Billard C, Sigaux F, Castaigne S, Valensi F, Flandrin G, Degos L, Falcoff E, Aguet M. Treatment of hairy cell leukemia with recombinant alpha interferon: II. In vivo down-regulation of alpha interferon receptors on tumor cells Blood. 67: 821-826. DOI: 10.1182/Blood.V67.3.821.Bloodjournal673821 |
0.435 |
|
| 1985 |
Merlin G, Falcoff E, Aguet M. 125I-labelled Human Interferons Alpha, Beta and Gamma: Comparative Receptor-binding Data Journal of General Virology. 66: 1149-1152. PMID 3158718 DOI: 10.1099/0022-1317-66-5-1149 |
0.394 |
|
| 1985 |
Aguet M, Salgam P, Gutte B, Arnheiter H. A crystalline synthetic peptide representing the epitope of a monoclonal antibody raised against synthetic interferon‐a1 fragment 111 – 166 Febs Journal. 146: 689-691. PMID 2578959 DOI: 10.1111/J.1432-1033.1985.Tb08705.X |
0.357 |
|
| 1984 |
Aguet M, Gröbke M, Dreiding P. Various human interferon alpha subclasses cross-react with common receptors: their binding affinities correlate with their specific biological activities. Virology. 132: 211-216. PMID 6320534 DOI: 10.1016/0042-6822(84)90105-3 |
0.37 |
|
| 1982 |
Aguet M, Belardelli F, Blanchard B, Marcucci F, Gresser I. High-affinity binding of 125I-labeled mouse interferon to a specific cell surface receptor. IV. Mouse gamma interferon and cholera toxin do not compete for the common receptor site of alpha / beta interferon. Virology. 117: 541-4. PMID 6175095 DOI: 10.1016/0042-6822(82)90497-4 |
0.374 |
|
| 1981 |
Aguet M, Vignaux F, Fridman WH, Gresser I. Enhancement of Fc gamma receptor expression in interferon-treated mice. European Journal of Immunology. 11: 926-930. PMID 6173231 DOI: 10.1002/Eji.1830111114 |
0.384 |
|
| 1981 |
Aguet M, Blanchard B. High affinity binding of 125I-Labeled mouse interferon to a specific cell surface receptor. II. Analysis of binding properties. Virology. 115: 249-61. PMID 6171930 DOI: 10.1016/0042-6822(81)90108-2 |
0.371 |
|
| 1981 |
Aguet M, Gresser I, Hovanessian AG, Bandu MT, Blanchard B, Blangy D. Specific high-affinity binding of 125I-labeled mouse interferon to interfevon resistant embryonal carcinoma cells in vitro. Virology. 114: 585-8. PMID 6170161 DOI: 10.1016/0042-6822(81)90241-5 |
0.37 |
|
| 1980 |
Aguet M. High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor Nature. 284: 459-461. PMID 6444699 DOI: 10.1038/284459A0 |
0.368 |
|
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