Thomas J. Lynch, Ph.D. - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Cystic Fibrosis, Stem Cells, Regenerative Medicine, Gene Therapy, Cell Therapy, Lung Transplantation

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Choi SH, Reeves RE, Romano Ibarra GS, Lynch TJ, Shahin WS, Feng Z, Gasser GN, Winter MC, Evans TIA, Liu X, Luo M, Zhang Y, Stoltz DA, Devor EJ, Yan Z, et al. Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b. Genes. 11. PMID 33036232 DOI: 10.3390/genes11101169  1
2020 Gao J, Petraki S, Sun X, Brooks LA, Lynch TJ, Hsieh CL, Elteriefi R, Lorenzana Z, Punj V, Engelhardt JF, Parekh KR, Ryan AL. Derivation of induced pluripotent stem cells from ferret somatic cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32073882 DOI: 10.1152/Ajplung.00456.2019  1
2019 Lynch TJ, Ievlev V, Parekh KR. Heterogeneity of Pulmonary Stem Cells. Advances in Experimental Medicine and Biology. 1169: 95-117. PMID 31487021 DOI: 10.1007/978-3-030-24108-7_6  1
2019 Yu M, Sun X, Tyler SR, Liang B, Swatek AM, Lynch TJ, He N, Yuan F, Feng Z, Rotti PG, Choi SH, Shahin W, Liu X, Yan Z, Engelhardt JF. Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus. Scientific Reports. 9: 1971. PMID 30760763 DOI: 10.1038/S41598-018-37192-4  1
2018 Lynch TJ, Ahlers BA, Parekh KR. Lung transplantation: chronic rejection and stem cell depletion. Journal of Thoracic Disease. 10: E666-E668. PMID 30233912 DOI: 10.21037/Jtd.2018.07.70  1
2018 Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, et al. Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. 22: 779. PMID 29727685 DOI: 10.1016/J.Stem.2018.04.007  1
2018 Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, et al. Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. PMID 29656941 DOI: 10.1016/J.Stem.2018.03.017  1
2017 Swatek AM, Lynch TJ, Crooke AK, Anderson PJ, Tyler SR, Brooks L, Ivanovic M, Klesney-Tait JA, Eberlein M, Pena T, Meyerholz DK, Engelhardt JF, Parekh KR. Depletion of Airway Submucosal Glands and TP63+KRT5+ Basal Cells in Obliterative Bronchiolitis. American Journal of Respiratory and Critical Care Medicine. PMID 29236513 DOI: 10.1164/Rccm.201707-1368Oc  1
2017 Anderson PJ, Lynch TJ, Engelhardt JF. Multipotent Myoepithelial Progenitor Cells Are Born Early During Airway Submucosal Gland Development. American Journal of Respiratory Cell and Molecular Biology. PMID 28125268 DOI: 10.1165/Rcmb.2016-0304Oc  1
2016 Sun Z, Yu W, Navarro MS, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, et al. Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development (Cambridge, England). PMID 27660324 DOI: 10.1242/Dev.138883  1
2016 Lynch TJ, Anderson PJ, Xie W, Crooke AK, Liu X, Tyler SR, Luo M, Kusner DM, Zhang Y, Neff T, Burnette DC, Walters KS, Goodheart MJ, Parekh KR, Engelhardt JF. Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands. Stem Cells (Dayton, Ohio). PMID 27341073 DOI: 10.1002/Stem.2443  1
2016 Purnell TS, Lynch TJ, Bone L, Segal JB, Evans C, Longo DR, Bridges JF. Perceived Barriers and Potential Strategies to Improve Self-Management Among Adults with Type 2 Diabetes: A Community-Engaged Research Approach. The Patient. PMID 26939674 DOI: 10.1007/S40271-016-0162-3  0.01
2015 Carrasco JM, Lynch TJ, Garralda E, Woitha K, Elsner F, Filbet M, Ellershaw JE, Clark D, Centeno C. Palliative Care Medical Education in European Universities: A Descriptive Study and Numerical Scoring System Proposal for Assessing Educational Development. Journal of Pain and Symptom Management. PMID 26025273 DOI: 10.1016/j.jpainsymman.2015.04.019  0.01
2015 Xie W, Fisher JT, Lynch TJ, Luo M, Evans TI, Neff TL, Zhou W, Zhang Y, Ou Y, Bunnett NW, Russo AF, Goodheart MJ, Parekh KR, Liu X, Engelhardt JF. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice. The Journal of Clinical Investigation. 125: 2179. PMID 25932677 DOI: 10.1172/Jci82138  1
2015 Jackman DM, Cioffredi LA, Jacobs L, Sharmeen F, Morse LK, Lucca J, Plotkin SR, Marcoux PJ, Rabin MS, Lynch TJ, Johnson BE, Kesari S. A phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer. Oncotarget. 6: 4527-36. PMID 25784657 DOI: 10.18632/Oncotarget.2886  0.01
2015 Heist RS, Duda DG, Sahani DV, Ancukiewicz M, Fidias P, Sequist LV, Temel JS, Shaw AT, Pennell NA, Neal JW, Gandhi L, Lynch TJ, Engelman JA, Jain RK. Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 1547-52. PMID 25605928 DOI: 10.1073/Pnas.1424024112  0.01
2015 Kosty MP, Wozniak AJ, Jahanzeb M, Leon L, Fish S, Hazard SJ, Lynch TJ. Effectiveness and safety of post-induction phase bevacizumab treatment for patients with non-small-cell lung cancer: results from the ARIES observational cohort study. Targeted Oncology. PMID 25559289 DOI: 10.1007/S11523-014-0355-4  0.01
2014 Lynch TJ, Spigel DR, Brahmer J, Fischbach N, Garst J, Jahanzeb M, Kumar P, Vidaver RM, Wozniak AJ, Fish S, Flick ED, Leon L, Hazard SJ, Kosty MP. Safety and effectiveness of bevacizumab-containing treatment for non-small-cell lung cancer: final results of the ARIES observational cohort study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1332-9. PMID 25122429 DOI: 10.1097/Jto.0000000000000257  0.01
2014 Lynch TJ, Engelhardt JF. Progenitor cells in proximal airway epithelial development and regeneration. Journal of Cellular Biochemistry. 115: 1637-45. PMID 24818588 DOI: 10.1002/Jcb.24834  1
2014 Sun X, Olivier AK, Yi Y, Pope CE, Hayden HS, Liang B, Sui H, Zhou W, Hager KR, Zhang Y, Liu X, Yan Z, Fisher JT, Keiser NW, Song Y, ... Lynch TJ, et al. Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets. The American Journal of Pathology. 184: 1309-22. PMID 24637292 DOI: 10.1016/J.Ajpath.2014.01.035  1
2014 Xie W, Lynch TJ, Liu X, Tyler SR, Yu S, Zhou X, Luo M, Kusner DM, Sun X, Yi Y, Zhang Y, Goodheart MJ, Parekh KR, Wells JM, Xue HH, et al. Sox2 modulates Lef-1 expression during airway submucosal gland development. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L645-60. PMID 24487391 DOI: 10.1152/Ajplung.00157.2013  1
2014 Pujol JL, Pirker R, Lynch TJ, Butts CA, Rosell R, Shepherd FA, Vansteenkiste J, O'Byrne KJ, de Blas B, Heighway J, von Heydebreck A, Thatcher N. Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 83: 211-8. PMID 24332319 DOI: 10.1016/j.lungcan.2013.11.006  0.01
2014 Sun X, Olivier AK, Liang B, Yi Y, Sui H, Evans TI, Zhang Y, Zhou W, Tyler SR, Fisher JT, Keiser NW, Liu X, Yan Z, Song Y, Goeken JA, ... Lynch TJ, et al. Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 50: 502-12. PMID 24074402 DOI: 10.1165/Rcmb.2013-0261Oc  1
2013 Spencer NY, Zhou W, Li Q, Zhang Y, Luo M, Yan Z, Lynch TJ, Abbott D, Banfi B, Engelhardt JF. Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G84-94. PMID 23639811 DOI: 10.1152/Ajpgi.00430.2012  1
2011 Xie W, Fisher JT, Lynch TJ, Luo M, Evans TI, Neff TL, Zhou W, Zhang Y, Ou Y, Bunnett NW, Russo AF, Goodheart MJ, Parekh KR, Liu X, Engelhardt JF. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice. The Journal of Clinical Investigation. 121: 3144-58. PMID 21765217 DOI: 10.1172/Jci41857  1
2005 Kwak EL, Sordella R, Bell DW, Godin-Heymann N, Okimoto RA, Brannigan BW, Harris PL, Driscoll DR, Fidias P, Lynch TJ, Rabindran SK, McGinnis JP, Wissner A, Sharma SV, Isselbacher KJ, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proceedings of the National Academy of Sciences of the United States of America. 102: 7665-70. PMID 15897464 DOI: 10.1073/Pnas.0502860102  1
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