Thomas J. Lynch, Ph.D. - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Cystic Fibrosis, Stem Cells, Regenerative Medicine, Gene Therapy, Cell Therapy, Lung Transplantation

17/168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gao J, Petraki S, Sun X, Brooks LA, Lynch TJ, Hsieh CL, Elteriefi R, Lorenzana Z, Punj V, Engelhardt JF, Parekh KR, Ryan AL. Derivation of induced pluripotent stem cells from ferret somatic cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32073882 DOI: 10.1152/Ajplung.00456.2019  0.686
2020 Jensen-Cody CW, Crooke A, Lynch T, Engelhardt J. Lef‐1 is Required for Proper Cell Cycle Progression in Airway Basal Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01752  0.403
2019 Lynch TJ, Ievlev V, Parekh KR. Heterogeneity of Pulmonary Stem Cells. Advances in Experimental Medicine and Biology. 1169: 95-117. PMID 31487021 DOI: 10.1007/978-3-030-24108-7_6  0.681
2019 Yu M, Sun X, Tyler SR, Liang B, Swatek AM, Lynch TJ, He N, Yuan F, Feng Z, Rotti PG, Choi SH, Shahin W, Liu X, Yan Z, Engelhardt JF. Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus. Scientific Reports. 9: 1971. PMID 30760763 DOI: 10.1038/S41598-018-37192-4  0.529
2018 Lynch TJ, Ahlers BA, Parekh KR. Lung transplantation: chronic rejection and stem cell depletion. Journal of Thoracic Disease. 10: E666-E668. PMID 30233912 DOI: 10.21037/Jtd.2018.07.70  0.643
2018 Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, et al. Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. 22: 779. PMID 29727685 DOI: 10.1016/J.Stem.2018.04.007  0.658
2018 Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, et al. Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. PMID 29656941 DOI: 10.1016/J.Stem.2018.03.017  0.712
2017 Swatek AM, Lynch TJ, Crooke AK, Anderson PJ, Tyler SR, Brooks L, Ivanovic M, Klesney-Tait JA, Eberlein M, Pena T, Meyerholz DK, Engelhardt JF, Parekh KR. Depletion of Airway Submucosal Glands and TP63+KRT5+ Basal Cells in Obliterative Bronchiolitis. American Journal of Respiratory and Critical Care Medicine. PMID 29236513 DOI: 10.1164/Rccm.201707-1368Oc  0.685
2017 Anderson PJ, Lynch TJ, Engelhardt JF. Multipotent Myoepithelial Progenitor Cells Are Born Early During Airway Submucosal Gland Development. American Journal of Respiratory Cell and Molecular Biology. PMID 28125268 DOI: 10.1165/Rcmb.2016-0304Oc  0.415
2016 Sun Z, Yu W, Navarro MS, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, et al. Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development (Cambridge, England). PMID 27660324 DOI: 10.1242/Dev.138883  0.421
2016 Lynch TJ, Anderson PJ, Xie W, Crooke AK, Liu X, Tyler SR, Luo M, Kusner DM, Zhang Y, Neff T, Burnette DC, Walters KS, Goodheart MJ, Parekh KR, Engelhardt JF. Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands. Stem Cells (Dayton, Ohio). PMID 27341073 DOI: 10.1002/Stem.2443  0.703
2015 Xie W, Fisher JT, Lynch TJ, Luo M, Evans TI, Neff TL, Zhou W, Zhang Y, Ou Y, Bunnett NW, Russo AF, Goodheart MJ, Parekh KR, Liu X, Engelhardt JF. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice. The Journal of Clinical Investigation. 125: 2179. PMID 25932677 DOI: 10.1172/Jci82138  0.721
2014 Lynch TJ, Engelhardt JF. Progenitor cells in proximal airway epithelial development and regeneration. Journal of Cellular Biochemistry. 115: 1637-45. PMID 24818588 DOI: 10.1002/Jcb.24834  0.5
2014 Sun X, Olivier AK, Yi Y, Pope CE, Hayden HS, Liang B, Sui H, Zhou W, Hager KR, Zhang Y, Liu X, Yan Z, Fisher JT, Keiser NW, Song Y, ... ... Lynch TJ, et al. Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets. The American Journal of Pathology. 184: 1309-22. PMID 24637292 DOI: 10.1016/J.Ajpath.2014.01.035  0.657
2014 Xie W, Lynch TJ, Liu X, Tyler SR, Yu S, Zhou X, Luo M, Kusner DM, Sun X, Yi Y, Zhang Y, Goodheart MJ, Parekh KR, Wells JM, Xue HH, et al. Sox2 modulates Lef-1 expression during airway submucosal gland development. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L645-60. PMID 24487391 DOI: 10.1152/Ajplung.00157.2013  0.647
2014 Sun X, Olivier AK, Liang B, Yi Y, Sui H, Evans TI, Zhang Y, Zhou W, Tyler SR, Fisher JT, Keiser NW, Liu X, Yan Z, Song Y, Goeken JA, ... ... Lynch TJ, et al. Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 50: 502-12. PMID 24074402 DOI: 10.1165/Rcmb.2013-0261Oc  0.67
2011 Xie W, Fisher JT, Lynch TJ, Luo M, Evans TI, Neff TL, Zhou W, Zhang Y, Ou Y, Bunnett NW, Russo AF, Goodheart MJ, Parekh KR, Liu X, Engelhardt JF. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice. The Journal of Clinical Investigation. 121: 3144-58. PMID 21765217 DOI: 10.1172/Jci41857  0.751
Low-probability matches (unlikely to be authored by this person)
2012 Goldberg SB, Supko JG, Neal JW, Muzikansky A, Digumarthy S, Fidias P, Temel JS, Heist RS, Shaw AT, McCarthy PO, Lynch TJ, Sharma S, Settleman JE, Sequist LV. A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1602-8. PMID 22878749 DOI: 10.1097/Jto.0B013E318262De4A  0.26
2009 Lynch TJ, Fenton D, Hirsh V, Bodkin D, Middleman EL, Chiappori A, Halmos B, Favis R, Liu H, Trepicchio WL, Eton O, Shepherd FA. A randomized phase 2 study of erlotinib alone and in combination with bortezomib in previously treated advanced non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 1002-9. PMID 19633475 DOI: 10.1097/JTO.0b013e3181aba89f  0.256
2020 Choi SH, Reeves RE, Romano Ibarra GS, Lynch TJ, Shahin WS, Feng Z, Gasser GN, Winter MC, Evans TIA, Liu X, Luo M, Zhang Y, Stoltz DA, Devor EJ, Yan Z, et al. Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b. Genes. 11. PMID 33036232 DOI: 10.3390/genes11101169  0.249
2009 Sequist LV, Fidias P, Heist RS, Ostler P, Muzikansky A, Lynch TJ. Brief report of biweekly pemetrexed and gemcitabine in elderly patients with non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 1170-3. PMID 19704338 DOI: 10.1097/JTO.0b013e3181b28efe  0.247
2009 Sequist LV, Nagrath S, Toner M, Haber DA, Lynch TJ. The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 281-3. PMID 19247082 DOI: 10.1097/Jto.0B013E3181989565  0.238
2013 Spencer NY, Zhou W, Li Q, Zhang Y, Luo M, Yan Z, Lynch TJ, Abbott D, Banfi B, Engelhardt JF. Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G84-94. PMID 23639811 DOI: 10.1152/Ajpgi.00430.2012  0.237
2010 Heist RS, Duda GD, Sahani D, Pennell NA, Neal JW, Ancukiewicz M, Engelman JA, Lynch TJ, Jain RK. In vivo assessment of the effects of bevacizumab in advanced non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 28: 7612-7612. DOI: 10.1200/Jco.2010.28.15_Suppl.7612  0.235
2016 Leon L, Kosty M, Jahanzeb M, Spigel D, Wozniak AJ, Brahmer J, Fish S, Flick ED, Hazard SJ, Lynch TJ. Effectiveness of bevacizumab exposure beyond disease progression in patients with non-small-cell lung cancer: analyses of the ARIES observational cohort study. Pharmacoepidemiology and Drug Safety. 25: 569-77. PMID 26748833 DOI: 10.1002/Pds.3948  0.231
2000 Salgia R, Lynch T, Skarin A, Lynch C, Lucca J, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, DeCamp M, Wain J, Mathiesen D, Wright C, Carey R, et al. A phase I study of vaccination with lethally irradiated, autologous nonsmall cell lung carcinoma cells engineered by adenoviral mediated gene transfer to secrete human granulocyte-macrophage colony stimulating factor Lung Cancer. 29: 186. DOI: 10.1016/S0169-5002(00)80626-1  0.229
1982 Matsumoto J, Lynch TJ, Grabowski SM, Taylor JD, Tchen TT. Induction of melanized cells from a goldfish erythrophoroma: isolation of pigment translocation variants. Science (New York, N.Y.). 217: 1149-51. PMID 6287577 DOI: 10.1126/science.6287577  0.224
2009 Fidias P, Pennell NA, Boral AL, Shapiro GI, Skarin AT, Eder JP, Kwoh TJ, Geary RS, Johnson BE, Lynch TJ, Supko JG. Phase I study of the c-raf-1 antisense oligonucleotide ISIS 5132 in combination with carboplatin and paclitaxel in patients with previously untreated, advanced non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 1156-62. PMID 19704336 DOI: 10.1097/JTO.0b013e3181b2793f  0.223
2008 Heist RS, Zhai R, Liu G, Zhou W, Lin X, Su L, Asomaning K, Lynch TJ, Wain JC, Christiani DC. VEGF polymorphisms and survival in early-stage non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 856-62. PMID 18281657 DOI: 10.1200/Jco.2007.13.5947  0.219
2009 Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, ... ... Lynch TJ, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 4247-53. PMID 19667264 DOI: 10.1200/Jco.2009.22.6993  0.219
2008 Heist RS, Fidias P, Huberman M, Ardman B, Sequist LV, Temel JS, Lynch TJ. A phase II study of oxaliplatin, pemetrexed, and bevacizumab in previously treated advanced non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 1153-8. PMID 18827612 DOI: 10.1097/JTO.0b013e318187273f  0.213
2012 Decker RH, Lynch TJ. Unmet challenges in the use of novel agents in locally advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 582-4. PMID 22271476 DOI: 10.1200/Jco.2011.40.1471  0.208
2009 Sequist LV, Engelman JA, Lynch TJ. Toward noninvasive genomic screening of lung cancer patients Journal of Clinical Oncology. 27: 2589-2591. PMID 19414671 DOI: 10.1200/JCO.2008.20.4875  0.202
2007 Gandhi L, Harding MW, Neubauer M, Langer CJ, Moore M, Ross HJ, Johnson BE, Lynch TJ. A phase II study of the safety and efficacy of the multidrug resistance inhibitor VX-710 combined with doxorubicin and vincristine in patients with recurrent small cell lung cancer. Cancer. 109: 924-32. PMID 17285598 DOI: 10.1002/cncr.22492  0.202
2007 Heist RS, Zhou W, Chirieac LR, Cogan-Drew T, Liu G, Su L, Neuberg D, Lynch TJ, Wain JC, Christiani DC. MDM2 polymorphism, survival, and histology in early-stage non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 2243-7. PMID 17538168 DOI: 10.1200/Jco.2006.08.8914  0.199
2007 Lynch TJ, Bonomi PD, Butts C, Davies AM, Engelman J, Govindan R, Herbst RS, Heymach JV, Johnson BE, Martins RG, Perez-Soler R, Riely GJ, Sandler AB, Sequist LV, Socinski MA, et al. Novel agents in the treatment of lung cancer: Fourth Cambridge Conference. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: s4583-8. PMID 17671145 DOI: 10.1158/1078-0432.CCR-07-0716  0.197
2007 Yee AJ, Lynch TJ. CT screening for lung cancer. The New England Journal of Medicine. 356: 744-5; author reply . PMID 17310519  0.196
2008 Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW, Digumarthy S, Muzikansky A, Irimia D, Settleman J, Tompkins RG, ... Lynch TJ, et al. Detection of mutations in EGFR in circulating lung-cancer cells. The New England Journal of Medicine. 359: 366-77. PMID 18596266 DOI: 10.1056/Nejmoa0800668  0.191
2010 Lynch TJ, Patel T, Dreisbach L, McCleod M, Heim WJ, Hermann RC, Paschold E, Iannotti NO, Dakhil S, Gorton S, Pautret V, Weber MR, Woytowitz D. Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: results of the randomized multicenter phase III trial BMS099. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 911-7. PMID 20100966 DOI: 10.1200/JCO.2009.21.9618  0.191
2008 Heist RS, Zhou W, Wang Z, Liu G, Neuberg D, Su L, Asomaning K, Hollis BW, Lynch TJ, Wain JC, Giovannucci E, Christiani DC. Circulating 25-hydroxyvitamin D, VDR polymorphisms, and survival in advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 5596-602. PMID 18936471 DOI: 10.1200/Jco.2008.18.0406  0.188
2012 Lynch TJ, Bondarenko I, Luft A, Serwatowski P, Barlesi F, Chacko R, Sebastian M, Neal J, Lu H, Cuillerot JM, Reck M. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 2046-54. PMID 22547592 DOI: 10.1200/Jco.2011.38.4032  0.187
2007 Zhou W, Heist RS, Liu G, Asomaning K, Neuberg DS, Hollis BW, Wain JC, Lynch TJ, Giovannucci E, Su L, Christiani DC. Circulating 25-hydroxyvitamin D levels predict survival in early-stage non-small-cell lung cancer patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 479-85. PMID 17290055 DOI: 10.1200/Jco.2006.07.5358  0.183
2010 Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, Ou SH, Dezube BJ, Jänne PA, Costa DB, Varella-Garcia M, Kim WH, Lynch TJ, Fidias P, Stubbs H, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. The New England Journal of Medicine. 363: 1693-703. PMID 20979469 DOI: 10.1056/Nejmoa1006448  0.182
2014 Pujol JL, Pirker R, Lynch TJ, Butts CA, Rosell R, Shepherd FA, Vansteenkiste J, O'Byrne KJ, de Blas B, Heighway J, von Heydebreck A, Thatcher N. Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 83: 211-8. PMID 24332319 DOI: 10.1016/j.lungcan.2013.11.006  0.182
2009 Temel JS, Greer JA, Goldberg S, Vogel PD, Sullivan M, Pirl WF, Lynch TJ, Christiani DC, Smith MR. A structured exercise program for patients with advanced non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 595-601. PMID 19276834 DOI: 10.1097/Jto.0B013E31819D18E5  0.179
1986 Lazo JS, Lynch TJ, McCallister J. Bleomycin inhibition of angiotensin-converting enzyme activity from serum, lungs, and cultured pulmonary artery endothelial cells. The American Review of Respiratory Disease. 134: 73-8. PMID 2425674 DOI: 10.1164/ARRD.1986.134.1.73  0.173
2008 Nanda A, Dias-Santagata DC, Stubbs H, O'Hara CJ, Zaner KS, Lynch TJ, Willers H. Unusual tumor response and toxicity from radiation and concurrent erlotinib for non-small-cell lung cancer. Clinical Lung Cancer. 9: 285-7. PMID 18824451 DOI: 10.3816/Clc.2008.N.044  0.172
2009 Lennes IT, Lynch TJ. Quality indicators in cancer care: development and implementation for improved health outcomes in non-small-cell lung cancer. Clinical Lung Cancer. 10: 341-6. PMID 19808192 DOI: 10.3816/CLC.2009.n.046  0.17
2007 Jackman DM, Yeap BY, Lindeman NI, Fidias P, Rabin MS, Temel J, Skarin AT, Meyerson M, Holmes AJ, Borras AM, Freidlin B, Ostler PA, Lucca J, Lynch TJ, Johnson BE, et al. Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 760-6. PMID 17228019 DOI: 10.1200/Jco.2006.07.5754  0.168
2008 Asomaning K, Miller DP, Liu G, Wain JC, Lynch TJ, Su L, Christiani DC. Second hand smoke, age of exposure and lung cancer risk. Lung Cancer (Amsterdam, Netherlands). 61: 13-20. PMID 18191495 DOI: 10.1016/J.Lungcan.2007.11.013  0.168
2008 Stinchcombe TE, Mauer AM, Hodgson LD, Herndon JE, Lynch TJ, Green MR, Vokes EE. Phase II trial of paclitaxel and cisplatin in patients with extensive stage small cell lung cancer: Cancer and Leukemia Group B Trial 9430. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 1301-7. PMID 18978566 DOI: 10.1097/JTO.0b013e318187494a  0.167
1983 Matsumoto J, Lynch TJ, Grabowski S, Richards CM, Lo SL, Clark C, Kern D, Taylor JD, Tchen TT, Ishikawa T, Masahito P, Takayama S. Fish tumor pigment cells: Differentiation and comparison to their normal counterparts Integrative and Comparative Biology. 23: 569-580. DOI: 10.1093/Icb/23.3.569  0.167
2008 Lynch TJ, Blumenschein GR, Engelman JA, Espinoza-Delgado I, Govindan R, Hanke J, Hanna NH, Heymach JV, Hirsch FR, Janne PA, Lilenbaum RC, Natale RB, Riely GJ, Sequist LV, Shapiro GI, et al. Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge conference assessing opportunities for combination therapy Journal of Thoracic Oncology. 3. PMID 18520291 DOI: 10.1097/JTO.0b013e318174e9d3  0.165
2009 Pao W, Kris MG, Iafrate AJ, Ladanyi M, Jänne PA, Wistuba II, Miake-Lye R, Herbst RS, Carbone DP, Johnson BE, Lynch TJ. Integration of molecular profiling into the lung cancer clinic. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5317-22. PMID 19706816 DOI: 10.1158/1078-0432.Ccr-09-0913  0.16
2015 Kosty MP, Wozniak AJ, Jahanzeb M, Leon L, Fish S, Hazard SJ, Lynch TJ. Effectiveness and safety of post-induction phase bevacizumab treatment for patients with non-small-cell lung cancer: results from the ARIES observational cohort study. Targeted Oncology. PMID 25559289 DOI: 10.1007/S11523-014-0355-4  0.158
2010 Suk Heist R, Fain J, Chinnasami B, Khan W, Molina JR, Sequist LV, Temel JS, Fidias P, Brainerd V, Leopold L, Lynch TJ. Phase I/II study of AT-101 with topotecan in relapsed and refractory small cell lung cancer Journal of Thoracic Oncology. 5: 1637-1643. PMID 20808253 DOI: 10.1097/JTO.0b013e3181e8f4dc  0.156
2006 Zhou W, Heist RS, Liu G, Asomaning K, Miller DP, Neuberg DS, Wain JC, Lynch TJ, Christiani DC. Second hand smoke exposure and survival in early-stage non-small-cell lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7187-93. PMID 17145845 DOI: 10.1158/1078-0432.Ccr-06-1460  0.155
2009 Sequist LV, Fidias PM, Temel JS, Kolevska T, Rabin MS, Boccia RV, Burris HA, Belt RJ, Huberman MS, Melnyk O, Mills GM, Englund CW, Caldwell DC, Keck JG, Meng L, ... ... Lynch TJ, et al. Phase 1-2a multicenter dose-ranging study of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy for patients with advanced non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 1389-96. PMID 19701107 DOI: 10.1097/JTO.0b013e3181b6b84b  0.154
2010 Sequist LV, Besse B, Lynch TJ, Miller VA, Wong KK, Gitlitz B, Eaton K, Zacharchuk C, Freyman A, Powell C, Ananthakrishnan R, Quinn S, Soria JC. Neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor: results of a phase II trial in patients with advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 3076-83. PMID 20479403 DOI: 10.1200/JCO.2009.27.9414  0.154
2009 Miksad RA, Gönen M, Lynch TJ, Roberts TG. Interpreting trial results in light of conflicting evidence: a Bayesian analysis of adjuvant chemotherapy for non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2245-52. PMID 19307513 DOI: 10.1200/JCO.2008.16.2586  0.152
2006 Heist RS, Marshall AL, Liu G, Zhou W, Su L, Neuberg D, Lynch TJ, Wain J, Christiani DC. Matrix metalloproteinase polymorphisms and survival in stage I non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5448-53. PMID 17000679 DOI: 10.1158/1078-0432.Ccr-06-0262  0.151
2010 Neal JW, Heist RS, Fidias P, Temel JS, Huberman M, Marcoux JP, Muzikansky A, Lynch TJ, Sequist LV. Cetuximab monotherapy in patients with advanced non-small cell lung cancer after prior epidermal growth factor receptor tyrosine kinase inhibitor therapy. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 1855-8. PMID 20975380 DOI: 10.1097/Jto.0B013E3181F0Bee0  0.144
2012 Pietanza MC, Gadgeel SM, Dowlati A, Lynch TJ, Salgia R, Rowland KM, Wertheim MS, Price KA, Riely GJ, Azzoli CG, Miller VA, Krug LM, Kris MG, Beumer JH, Tonda M, et al. Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 856-65. PMID 22722787 DOI: 10.1097/Jto.0B013E31824C943F  0.139
2008 Greer JA, Pirl WF, Park ER, Lynch TJ, Temel JS. Behavioral and psychological predictors of chemotherapy adherence in patients with advanced non-small cell lung cancer. Journal of Psychosomatic Research. 65: 549-52. PMID 19027443 DOI: 10.1016/J.Jpsychores.2008.03.005  0.138
1975 Lynch TJ, Tallant EA, Cheung WY. Brevibacterium liquefaciens adenylate cyclase and its in vivo stimulation by pyruvate. Journal of Bacteriology. 124: 1106-12. PMID 172486  0.138
2014 Lynch TJ, Spigel DR, Brahmer J, Fischbach N, Garst J, Jahanzeb M, Kumar P, Vidaver RM, Wozniak AJ, Fish S, Flick ED, Leon L, Hazard SJ, Kosty MP. Safety and effectiveness of bevacizumab-containing treatment for non-small-cell lung cancer: final results of the ARIES observational cohort study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1332-9. PMID 25122429 DOI: 10.1097/Jto.0000000000000257  0.138
2008 Chin TM, Quinlan MP, Singh A, Sequist LV, Lynch TJ, Haber DA, Sharma SV, Settleman J. Reduced Erlotinib sensitivity of epidermal growth factor receptor-mutant non-small cell lung cancer following cisplatin exposure: a cell culture model of second-line erlotinib treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6867-76. PMID 18980981 DOI: 10.1158/1078-0432.Ccr-08-0093  0.137
1989 Fukui Y, Lynch TJ, Brzeska H, Korn ED. Myosin I is located at the leading edges of locomoting Dictyostelium amoebae. Nature. 341: 328-31. PMID 2797149 DOI: 10.1038/341328A0  0.137
2011 Temel JS, Greer JA, Admane S, Gallagher ER, Jackson VA, Lynch TJ, Lennes IT, Dahlin CM, Pirl WF. Longitudinal perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer: results of a randomized study of early palliative care. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2319-26. PMID 21555700 DOI: 10.1200/Jco.2010.32.4459  0.136
2008 Zhai R, Liu G, Zhou W, Su L, Heist RS, Lynch TJ, Wain JC, Asomaning K, Lin X, Christiani DC. Vascular endothelial growth factor genotypes, haplotypes, gender, and the risk of non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 612-7. PMID 18223238 DOI: 10.1158/1078-0432.Ccr-07-1655  0.136
2008 Pirl WF, Temel JS, Billings A, Dahlin C, Jackson V, Prigerson HG, Greer J, Lynch TJ. Depression after diagnosis of advanced non-small cell lung cancer and survival: a pilot study. Psychosomatics. 49: 218-24. PMID 18448776 DOI: 10.1176/Appi.Psy.49.3.218  0.136
2015 Jackman DM, Cioffredi LA, Jacobs L, Sharmeen F, Morse LK, Lucca J, Plotkin SR, Marcoux PJ, Rabin MS, Lynch TJ, Johnson BE, Kesari S. A phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer. Oncotarget. 6: 4527-36. PMID 25784657 DOI: 10.18632/Oncotarget.2886  0.132
2009 Herbst RS, Lynch TJ, Sandler AB. Beyond doublet chemotherapy for advanced non-small-cell lung cancer: combination of targeted agents with first-line chemotherapy. Clinical Lung Cancer. 10: 20-7. PMID 19289368 DOI: 10.3816/CLC.2009.n.003  0.129
2008 Liu G, Wheatley-Price P, Zhou W, Park S, Heist RS, Asomaning K, Wain JC, Lynch TJ, Su L, Christiani DC. Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk. International Journal of Cancer. Journal International Du Cancer. 122: 915-8. PMID 17957785 DOI: 10.1002/Ijc.23178  0.128
2011 Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, ... Lynch TJ, et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Science Translational Medicine. 3: 75ra26. PMID 21430269 DOI: 10.1126/scitranslmed.3002003  0.127
2013 Choi NC, Chun TT, Niemierko A, Ancukiewicz M, Fidias PM, Kradin RL, Mathisen DJ, Lynch TJ, Fischman AJ. Potential of 18F-FDG PET toward personalized radiotherapy or chemoradiotherapy in lung cancer. European Journal of Nuclear Medicine and Molecular Imaging. 40: 832-41. PMID 23400506 DOI: 10.1007/s00259-013-2348-4  0.124
2010 Eichler AF, Kahle KT, Wang DL, Joshi VA, Willers H, Engelman JA, Lynch TJ, Sequist LV. EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer. Neuro-Oncology. 12: 1193-9. PMID 20627894 DOI: 10.1200/Jco.2010.28.15_Suppl.7542  0.122
2010 Khambata-Ford S, Harbison CT, Hart LL, Awad M, Xu LA, Horak CE, Dakhil S, Hermann RC, Lynch TJ, Weber MR. Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 918-27. PMID 20100958 DOI: 10.1200/JCO.2009.25.2890  0.122
2007 Temel JS, Jackson VA, Billings JA, Dahlin C, Block SD, Buss MK, Ostler P, Fidias P, Muzikansky A, Greer JA, Pirl WF, Lynch TJ. Phase II study: integrated palliative care in newly diagnosed advanced non-small-cell lung cancer patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 2377-82. PMID 17557950 DOI: 10.1200/Jco.2006.09.2627  0.122
2008 Sequist LV, Martins RG, Spigel D, Grunberg SM, Spira A, Jänne PA, Joshi VA, McCollum D, Evans TL, Muzikansky A, Kuhlmann GL, Han M, Goldberg JS, Settleman J, Iafrate AJ, ... ... Lynch TJ, et al. First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2442-9. PMID 18458038 DOI: 10.1200/Jco.2007.14.8494  0.121
2008 Sequist LV, Lynch TJ. EGFR tyrosine kinase inhibitors in lung cancer: an evolving story. Annual Review of Medicine. 59: 429-42. PMID 17716025 DOI: 10.1146/annurev.med.59.090506.202405  0.114
2006 Haber DA, Bell DW, Sordella R, Kwak EL, Godin-Heymann N, Sharma SV, Lynch TJ, Settleman J. Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors. Cold Spring Harbor Symposia On Quantitative Biology. 70: 419-26. PMID 16869779 DOI: 10.1101/Sqb.2005.70.043  0.114
2007 Sequist LV, Bell DW, Lynch TJ, Haber DA. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 587-95. PMID 17290067 DOI: 10.1200/Jco.2006.07.3585  0.113
2006 Zhou W, Heist RS, Liu G, Neuberg DS, Asomaning K, Su L, Wain JC, Lynch TJ, Giovannucci E, Christiani DC. Polymorphisms of vitamin D receptor and survival in early-stage non-small cell lung cancer patients. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 2239-45. PMID 17119052 DOI: 10.1158/1055-9965.Epi-06-0023  0.11
2015 Heist RS, Duda DG, Sahani DV, Ancukiewicz M, Fidias P, Sequist LV, Temel JS, Shaw AT, Pennell NA, Neal JW, Gandhi L, Lynch TJ, Engelman JA, Jain RK. Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 1547-52. PMID 25605928 DOI: 10.1073/Pnas.1424024112  0.109
2009 Pennell NA, Lynch TJ. Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC. The Oncologist. 14: 399-411. PMID 19357226 DOI: 10.1634/theoncologist.2008-0276  0.109
2012 Politi K, Lynch TJ. Two sides of the same coin: EGFR exon 19 deletions and insertions in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1490-2. PMID 22317760 DOI: 10.1158/1078-0432.Ccr-11-3282  0.102
2005 Kwak EL, Sordella R, Bell DW, Godin-Heymann N, Okimoto RA, Brannigan BW, Harris PL, Driscoll DR, Fidias P, Lynch TJ, Rabindran SK, McGinnis JP, Wissner A, Sharma SV, Isselbacher KJ, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proceedings of the National Academy of Sciences of the United States of America. 102: 7665-70. PMID 15897464 DOI: 10.1073/Pnas.0502860102  0.1
2007 Lynch TJ, Kim ES, Eaby B, Garey J, West DP, Lacouture ME. Epidermal growth factor receptor inhibitor-associated cutaneous toxicities: an evolving paradigm in clinical management. The Oncologist. 12: 610-21. PMID 17522250 DOI: 10.1634/theoncologist.12-5-610  0.099
2012 Lynch TJ. Choosing optimal antimicrobial therapies. The Medical Clinics of North America. 96: 1079-94. PMID 23102478 DOI: 10.1016/j.mcna.2012.08.006  0.099
2007 Sequist LV, Joshi VA, Jänne PA, Muzikansky A, Fidias P, Meyerson M, Haber DA, Kucherlapati R, Johnson BE, Lynch TJ. Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. The Oncologist. 12: 90-8. PMID 17285735 DOI: 10.1634/Theoncologist.12-1-90  0.098
2008 Ter-Minassian M, Zhai R, Asomaning K, Su L, Zhou W, Liu G, Heist RS, Lynch TJ, Wain JC, Lin X, De Vivo I, Christiani DC. Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer. Carcinogenesis. 29: 2147-52. PMID 18757527 DOI: 10.1093/Carcin/Bgn205  0.097
2010 Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, Dahlin CM, Blinderman CD, Jacobsen J, Pirl WF, Billings JA, Lynch TJ. Early palliative care for patients with metastatic non-small-cell lung cancer. The New England Journal of Medicine. 363: 733-42. PMID 20818875 DOI: 10.1056/Nejmoa1000678  0.092
1985 Lynch TJ, Blackwell GJ, Moncada S. Carbon tetrachloride-induced eicosanoid synthesis and enzyme release from rat peritoneal leucocytes. Biochemical Pharmacology. 34: 1515-22. PMID 2986650 DOI: 10.1016/0006-2952(85)90693-8  0.089
1975 Lynch TJ, Tallant EA, Cheung WY. Separate genetic regulation of cyclic nucleotide phosphodiesterase and its protein activator in cultured mouse fibroblasts. Biochemical and Biophysical Research Communications. 63: 967-70. PMID 165822  0.086
1990 Wu BY, Yu FX, Lynch TJ, Taylor JD, Tchen TT. Partial characterization of a carotenoid droplet ATPase and its possible significance in carotenoid droplet dispersion in goldfish xanthophores. Cell Motility and the Cytoskeleton. 15: 147-55. PMID 2138933 DOI: 10.1002/cm.970150303  0.084
1989 Palazzo RE, Lynch TJ, Lo SJ, Taylor JD, Tchen TT. Rearrangements of pterinosomes and cytoskeleton accompanying pigment dispersion in goldfish xanthophores. Cell Motility and the Cytoskeleton. 13: 9-20. PMID 2543509 DOI: 10.1002/Cm.970130103  0.083
2008 Temel JS, McCannon J, Greer JA, Jackson VA, Ostler P, Pirl WF, Lynch TJ, Billings JA. Aggressiveness of care in a prospective cohort of patients with advanced NSCLC. Cancer. 113: 826-33. PMID 18618579 DOI: 10.1002/Cncr.23620  0.078
2016 Purnell TS, Lynch TJ, Bone L, Segal JB, Evans C, Longo DR, Bridges JF. Perceived Barriers and Potential Strategies to Improve Self-Management Among Adults with Type 2 Diabetes: A Community-Engaged Research Approach. The Patient. PMID 26939674 DOI: 10.1007/S40271-016-0162-3  0.076
1988 Tchen TT, Lo SJ, Lynch TJ, Palazzo RE, Peng G, Walker GR, Wu BY, Yu FX, Taylor JD. Regulation of the distribution of carotenoid droplets in goldfish xanthophores and possible implication to secretory processes. Cell Motility and the Cytoskeleton. 10: 143-52. PMID 2972398 DOI: 10.1002/Cm.970100119  0.076
2010 Dias-Santagata D, Akhavanfard S, David SS, Vernovsky K, Kuhlmann G, Boisvert SL, Stubbs H, McDermott U, Settleman J, Kwak EL, Clark JW, Isakoff SJ, Sequist LV, Engelman JA, Lynch TJ, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. Embo Molecular Medicine. 2: 146-58. PMID 20432502 DOI: 10.1002/Emmm.201000070  0.072
1975 Lynch TJ, Tallant EA, Cheung WY. Marked reduction of cyclic GMP phosphodiesterase activity in virally transformed mouse fibroblasts. Biochemical and Biophysical Research Communications. 65: 1115-22. PMID 168890  0.068
2008 Bradbury PA, Heist RS, Kulke MH, Zhou W, Marshall AL, Miller DP, Su L, Park S, Temel J, Fidias P, Sequist L, Lynch TJ, Wain JC, Shepherd FA, Christiani DC, et al. A rapid outcomes ascertainment system improves the quality of prognostic and pharmacogenetic outcomes from observational studies. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 204-11. PMID 18199725 DOI: 10.1158/1055-9965.Epi-07-0470  0.067
2009 Bradbury PA, Kulke MH, Heist RS, Zhou W, Ma C, Xu W, Marshall AL, Zhai R, Hooshmand SM, Asomaning K, Su L, Shepherd FA, Lynch TJ, Wain JC, Christiani DC, et al. Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes. Pharmacogenetics and Genomics. 19: 613-25. PMID 19620936 DOI: 10.1097/Fpc.0B013E32832F3010  0.065
1963 LYNCH TJ, MOLONEY WC. Observations on Serum B12 and Folate Activity in Normal and Leukemic Rats Blood. 21: 764-768. DOI: 10.1182/blood.V21.6.764.764  0.064
1982 Lo SJ, Grabowski SM, Lynch TJ, Kern DG, Taylor JD, Tchen TT. Isolation of xanthophores from the goldfish (Carassius auratus L.). In Vitro. 18: 356-60. PMID 6288547 DOI: 10.1007/BF02796335  0.062
2000 Orton DF, LeVeen RF, Saigh JA, Culp WC, Fidler JL, Lynch TJ, Goertzen TC, McCowan TC. Aortic prosthetic graft infections: radiologic manifestations and implications for management. Radiographics : a Review Publication of the Radiological Society of North America, Inc. 20: 977-93. PMID 10903688 DOI: 10.1148/RADIOGRAPHICS.20.4.G00JL12977  0.062
2008 Tse D, Zhai R, Zhou W, Heist RS, Asomaning K, Su L, Lynch TJ, Wain JC, Christiani DC, Liu G. Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk. Cancer Causes & Control : Ccc. 19: 1077-83. PMID 18478337 DOI: 10.1007/S10552-008-9171-4  0.06
1987 Marks JR, Lynch TJ, Karlinsey JE, Thomashow MF. Agrobacterium tumefaciens virulence locus pscA is related to the Rhizobium meliloti exoC locus Journal of Bacteriology. 169: 5835-5837. PMID 3680180 DOI: 10.1128/Jb.169.12.5835-5837.1987  0.055
2007 Liu G, Zhou W, Yeap BY, Su L, Wain JC, Poneros JM, Nishioka NS, Lynch TJ, Christiani DC. XRCC1 and XPD polymorphisms and esophageal adenocarcinoma risk. Carcinogenesis. 28: 1254-8. PMID 17264068 DOI: 10.1093/Carcin/Bgm020  0.054
1975 Lynch TJ, Cheung WY. Underestimation of cyclic 3',5'-nucleotide phosphodiesterase activity by a radioisotopic assay using an anionic-exchange resin. Analytical Biochemistry. 67: 130-8. PMID 167606 DOI: 10.1016/0003-2697(75)90280-8  0.052
2009 Zhu AX, Ready N, Clark JW, Safran H, Amato A, Salem N, Pace S, He X, Zvereva N, Lynch TJ, Ryan DP, Supko JG. Phase I and pharmacokinetic study of gimatecan given orally once a week for 3 of 4 weeks in patients with advanced solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 374-81. PMID 19118068 DOI: 10.1158/1078-0432.CCR-08-1024  0.051
2006 Temel JS, Pirl WF, Recklitis CJ, Cashavelly B, Lynch TJ. Feasibility and validity of a one-item fatigue screen in a thoracic oncology clinic. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 1: 454-9. PMID 17409899  0.049
1982 JENSEN CM, LYNCH TJ, KNOBLER CB, KAESZ HD. ChemInform Abstract: SYNTHESIS AND STRUCTURE DETERMINATION OF OS3(1,2-μ-H;1,2-μ-O:C(ME))(1-C(OME)ME)(CO)9: THE FIRST CLUSTER COMPLEX CONTAINING A FISCHER-TYPE CARBENE GROUP Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198247321  0.045
1975 Cheung WY, Bradham LS, Lynch TJ, Lin YM, Tallant EA. Protein activator of cyclic 3':5'-nucleotide phosphodiesterase of bovine or rat brain also activates its adenylate cyclase. Biochemical and Biophysical Research Communications. 66: 1055-62. PMID 170936  0.041
1989 Palazzo RE, Lynch TJ, Taylor JD, Tchen TT. cAMP-independent and cAMP-dependent protein phosphorylations by isolated goldfish xanthophore cytoskeletons: evidence for the association of cytoskeleton with a carotenoid droplet protein. Cell Motility and the Cytoskeleton. 13: 21-9. PMID 2543507 DOI: 10.1002/Cm.970130104  0.04
1989 Dalrymple GV, Lynch TJ, Hardin JW. Deinococcus radiodurans DNA increases the radiation resistance of Escherichia coli Radiation Research. 120: 532-536. PMID 2687934 DOI: 10.2307/3577802  0.038
2017 Aslakson RA, Schuster ALR, Lynch TJ, Weiss MJ, Gregg L, Miller J, Isenberg SR, Crossnohere NL, Conca-Cheng AM, Volandes AE, Smith TJ, Bridges JFP. Developing the Storyline for an Advance Care Planning Video for Surgery Patients: Patient-Centered Outcomes Research Engagement from Stakeholder Summit to State Fair. Journal of Palliative Medicine. PMID 28817359 DOI: 10.1089/Jpm.2017.0106  0.038
1990 Lynch TJ, Adler MW, Eisenstein TK. Comparison of the mechanisms of interleukin-1 and morphine-induced hyperthermia in the rat Annals of the New York Academy of Sciences. 594: 469-471. DOI: 10.1111/J.1749-6632.1990.Tb40531.X  0.038
1973 Lynch TJ, Henney HR. Carbohydrate metabolism during differentiation (sclerotization) of the myxomycete Physarum flavicomum. Archiv Fur Mikrobiologie. 90: 189-98. PMID 4350874 DOI: 10.1007/BF00424971  0.038
1980 Lynch TJ, Newcomb M, Bergbreiter DE, Hall MB. Molecular structure of the lithium enolate of acetaldehyde The Journal of Organic Chemistry. 45: 5005-5006. DOI: 10.1021/Jo01312A045  0.037
1989 Lynch TJ, Helvenston MC, Rheingold AL, Staley DL. Metal carbonyl complexes of the trindenyl ligand: crystal structure of trans-[Re(CO)3]3(trindenyl) Organometallics. 8: 1959-1963. DOI: 10.1021/Om00110A018  0.034
1988 Korn ED, Atkinson MA, Brzeska H, Hammer JA, Jung G, Lynch TJ. Structure-function studies on Acanthamoeba myosins IA, IB, and II. Journal of Cellular Biochemistry. 36: 37-50. PMID 3277984 DOI: 10.1002/Jcb.240360105  0.032
1982 Jensen CM, Lynch TJ, Knobler CB, Kaesz HD. Synthesis and structure determination of Os3[1,2-.mu.-H;1,2-.mu.-O:C(Me)][1-C(OMe)Me][CO)9: the first cluster complex containing a Fischer-type carbene group Journal of the American Chemical Society. 104: 4679-4680. DOI: 10.1021/Ja00381A031  0.031
1969 Henney HR, Lynch T. Growth of Physarum flavicomum and Physarum rigidum in chemically defined minimal media. Journal of Bacteriology. 99: 531-4. PMID 5817554 DOI: 10.1128/jb.99.2.531-534.1969  0.03
1992 Bang H, Lynch TJ, Basolo F. Kinetics and mechanism of carbon monoxide substitution of (.eta.5-Ind)Re(CO)3 (Ind = indenyl) with phosphines and phosphites. The indenyl ligand effect on related trindenylmetal carbonyls Organometallics. 11: 40-48. DOI: 10.1021/Om00037A015  0.03
2008 Zhai R, Liu G, Asomaning K, Su L, Kulke MH, Heist RS, Nishioka NS, Lynch TJ, Wain JC, Lin X, Christiani DC. Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk. Carcinogenesis. 29: 2330-4. PMID 18780893 DOI: 10.1093/Carcin/Bgn210  0.029
1976 Lynch TJ, Tallant EA, Cheung WY. Ca++-dependent formation of brain adenylate cyclase-protein activator complex. Biochemical and Biophysical Research Communications. 68: 616-25. PMID 814900  0.028
1978 Brown RK, Johnson PL, Lynch TJ, Williams JM. Structural studies of precursor and partially oxidized conducting complexes. XIV. An X-ray diffraction investigation of one-dimensional potassium tetracyanoplatinate bifluoride trihydrate Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34: 1965-1968. DOI: 10.1107/S0567740878007074  0.027
2009 Cescon DW, Bradbury PA, Asomaning K, Hopkins J, Zhai R, Zhou W, Wang Z, Kulke M, Su L, Ma C, Xu W, Marshall AL, Heist RS, Wain JC, Lynch TJ, et al. p53 Arg72Pro and MDM2 T309G polymorphisms, histology, and esophageal cancer prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3103-9. PMID 19383811 DOI: 10.1158/1078-0432.Ccr-08-3120  0.027
2008 Wright CD, Choi NC, Wain JC, Mathisen DJ, Lynch TJ, Fidias P. Induction chemoradiotherapy followed by resection for locally advanced Masaoka stage III and IVA thymic tumors. The Annals of Thoracic Surgery. 85: 385-9. PMID 18222230 DOI: 10.1016/j.athoracsur.2007.08.051  0.025
2008 Pennell NA, Daniels GH, Haddad RI, Ross DS, Evans T, Wirth LJ, Fidias PH, Temel JS, Gurubhagavatula S, Heist RS, Clark JR, Lynch TJ. A phase II study of gefitinib in patients with advanced thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 18: 317-23. PMID 17985985 DOI: 10.1089/thy.2007.0120  0.025
1988 Lynch TJ, Dominguez R, Helvenston MC. Synthesis of the trimetallic manganese and rhenium complexes: N[CH2(.eta.5-C5H4)M(CO)3]3. Derivatives of the nonadentate "TCp" ligand tris(cyclopentadienylmethyl)amine trianion Organometallics. 7: 2566-2567. DOI: 10.1021/OM00102A024  0.024
2007 Penson RT, Gu F, Harris S, Thiel MM, Lawton N, Fuller AF, Lynch TJ. Hope. The Oncologist. 12: 1105-13. PMID 17914080 DOI: 10.1634/theoncologist.12-9-1105  0.024
1991 Lynch TJ, Brzeska H, Baines IC, Korn ED. Purification of myosin I and myosin I heavy chain kinase from Acanthamoeba castellanii. Methods in Enzymology. 196: 12-23. PMID 1851936 DOI: 10.1016/0076-6879(91)96004-B  0.023
1989 Tisch TL, Lynch TJ, Dominguez R. Polymetallic compounds of extended polyaromatic ligands. Rhenium and manganese carbonyl derivatives of truxene Journal of Organometallic Chemistry. 377: 265-273. DOI: 10.1016/0022-328X(89)80088-9  0.022
1984 LYNCH TJ, BANAH M, KAESZ HD, PORTER CR. ChemInform Abstract: HYDROGENATION OF ANTHRACENE AND NITROGEN HETEROCYCLES CATALYZED BY IRON PENTACARBONYL UNDER WATER-GAS SHIFT CONDITIONS Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198434125  0.02
1983 Bergbreiter DE, Lynch TJ, Shimazu S. Nuclear magnetic resonance studies of methylsilver(I) complexes Organometallics. 2: 1354-1359. DOI: 10.1021/Om50004A017  0.02
1977 Lynch TJ, Tallant EA, Cheung WY. Rat brain adenylate cyclase. Further studies on its stimulation by a Ca2+-binding protein. Archives of Biochemistry and Biophysics. 182: 124-33. PMID 407845  0.019
2010 Penson RT, Schapira L, Mack S, Stanzler M, Lynch TJ. Connection: Schwartz Center Rounds at Massachusetts General Hospital Cancer Center. The Oncologist. 15: 760-4. PMID 20584809 DOI: 10.1634/theoncologist.2009-0329  0.019
2015 Murphy T, Tuzova A, O`Rourke CJ, S O, Greene C, Sullivan L, Thornhill J, Barrett C, Loftus B, Lynch T, Perry A. Multigene Methylation Biomarker Analysis in Prostate Cancer Epigenetic Diagnosis & Therapy. 1: 19-27. DOI: 10.2174/2214083201666150221001559  0.018
1984 Lynch TJ, Banah M, Kaesz HD, Porter CR. Hydrogenation of anthracene and nitrogen heterocycles catalyzed by iron pentacarbonyl under water-gas shift conditions The Journal of Organic Chemistry. 49: 1266-1270. DOI: 10.1021/jo00181a026  0.017
1987 Helvenston MC, Lynch TJ. Asymmetric recognition between triosmium clusters and their .mu.-acyl ligands Organometallics. 6: 208-210. DOI: 10.1021/OM00144A047  0.017
2008 Wang G, Lee A, Ivanov L, Lynch TJ, Serratella C, Basu R. A statistical investigation of time-variant hull girder strength of aging ships and coating life Marine Structures. 21: 240-256. DOI: 10.1016/J.MARSTRUC.2007.10.002  0.015
1981 Bergbreiter DE, Lynch TJ. Thermolysis of butylsilver(I) ate complexes The Journal of Organic Chemistry. 46: 727-733. DOI: 10.1021/Jo00317A015  0.014
1994 Winter R, Pierce DT, Geiger WE, Lynch TJ. Stepwise oxidation of three communicating metal centres: Electrochemistry of trinuclear trindenyl complexes of manganese or rhodium Journal of the Chemical Society, Chemical Communications. 1949-1950. DOI: 10.1039/C39940001949  0.014
1979 Lynch TJ, Cheung WY. Human erythrocyte Ca2+-Mg2+-ATPase: mechanism of stimulation by Ca2+. Archives of Biochemistry and Biophysics. 194: 165-70. PMID 156003 DOI: 10.1016/0003-9861(79)90606-4  0.014
2015 Carrasco JM, Lynch TJ, Garralda E, Woitha K, Elsner F, Filbet M, Ellershaw JE, Clark D, Centeno C. Palliative Care Medical Education in European Universities: A Descriptive Study and Numerical Scoring System Proposal for Assessing Educational Development. Journal of Pain and Symptom Management. PMID 26025273 DOI: 10.1016/j.jpainsymman.2015.04.019  0.013
2012 Lynch TJ, Carroll JM, Helvenston MC, Tisch TL, Rheingold AL, Staley DL, Mahmoudkhani A. Trindenyl trimolybdenum and tritungsten complexes: Crystal structure of (trindenyl)[(OC) 3W-W(CO) 3]W(CO) 3Bn Organometallics. 31: 3300-3307. DOI: 10.1021/Om3001263  0.012
1982 Lynch TJ, Banah M, McDougall M, Kaesz HD, Porter CR. Synergism and phase transfer effects in hydrogenations of model coal constituents using iron carbonyl as a catalyst Journal of Molecular Catalysis. 17: 109-113. DOI: 10.1016/0304-5102(82)80082-5  0.012
1981 Lee JY, Lynch TJ, Mao DT, Bergbreiter DE, Newcomb M. Facile carbon-carbon bond rotation in azaallyllithium reagents Journal of the American Chemical Society. 103: 6215-6217. DOI: 10.1021/Ja00410A042  0.011
2009 Wong KK, Fracasso PM, Bukowski RM, Lynch TJ, Munster PN, Shapiro GI, Jänne PA, Eder JP, Naughton MJ, Ellis MJ, Jones SF, Mekhail T, Zacharchuk C, Vermette J, Abbas R, et al. A phase I study with neratinib (HKI-272), an irreversible pan ErbB receptor tyrosine kinase inhibitor, in patients with solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2552-8. PMID 19318484 DOI: 10.1158/1078-0432.CCR-08-1978  0.01
2010 Lynch TJ, Khambata-Ford S. Reply to I. Floriani et al Journal of Clinical Oncology. 28: e468-e468. DOI: 10.1200/JCO.2010.28.8290  0.01
2009 Pirl WF, Solis J, Greer J, Sequist L, Temel JS, Lynch TJ. Epidermal growth factor receptor tyrosine kinase inhibitors and depression. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e49-50; author reply. PMID 19597022 DOI: 10.1200/Jco.2009.22.5219  0.01
2009 Bradbury PA, Zhai R, Ma C, Xu W, Hopkins J, Kulke MJ, Asomaning K, Wang Z, Su L, Heist RS, Lynch TJ, Wain JC, Christiani D, Liu G. Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4680-5. PMID 19584152 DOI: 10.1158/1078-0432.Ccr-09-0192  0.01
1989 Hartzell CJ, Stein PC, Lynch TJ, Werbelow LG, Earl WL. Differential line broadening in the NMR spectrum of methanol adsorbed on sol-gel silica Journal of the American Chemical Society. 111: 5114-5119. DOI: 10.1021/JA00196A014  0.01
1989 Helvenston MC, Lynch TJ. Trindenyl[tris(rheniumtricarbonyl)] Journal of Organometallic Chemistry. 359: C50-C52. DOI: 10.1016/0022-328X(89)85441-5  0.01
1987 Gallagher GJ, Lynch TJ, Fitzsimons B. Lodgepole pine in the Republic of Ireland II. Yield and management of coastal lodgepole pine Forest Ecology and Management. 22: 185-203. DOI: 10.1016/0378-1127(87)90104-6  0.01
1986 Tchen TT, Allen RD, Lo SC, Lynch TJ, Palazzo RE, Hayden J, Walker GR, Taylor JD. Role of microtubules in the formation of carotenoid droplet aggregate in goldfish xanthophores. Annals of the New York Academy of Sciences. 466: 887-94. PMID 3460460 DOI: 10.1111/J.1749-6632.1986.Tb38474.X  0.01
1984 BERGBREITER DE, CHEN B, LYNCH TJ. ChemInform Abstract: PALLADIUM/POLYSTYRENE CATALYSTS Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198418082  0.01
1983 Bergbreiter DE, Chen B, Lynch TJ. Palladium/polystyrene catalysts The Journal of Organic Chemistry. 48: 4179-4186. DOI: 10.1002/Chin.198418082  0.01
1981 Lynch TJ, Lo SJ, Taylor JD, Tchen TT. Characterization of and hormonal effects on subcellular fractions from xanthophores of the goldfish Carassius auratus L. Biochemical and Biophysical Research Communications. 102: 127-34. PMID 6272788 DOI: 10.1016/0006-291X(81)91498-4  0.01
1981 LYNCH TJ, NEWCOMB M, BERGBREITER DE, HALL MB. ChemInform Abstract: MOLECULAR STRUCTURE OF THE LITHIUM ENOLATE OF ACETALDEHYDE Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198114069  0.01
1980 Dominguez R, Lynch TJ, Wang F. Stabilization of the bis(diphenylphosphino) methanide ion by bridging dirhenium octacarbonyl: [Li(THF)4 ]IRe2(CO)8(Ph2PCHPPh2)] Journal of Organometallic Chemistry. 338: C7-C10. DOI: 10.1016/0022-328X(80)83016-6  0.01
1979 Swain CG, Powell AL, Lynch TJ, Alpha SR, Dunlap RP. Reduction of benzaldehyde by methoxide ion in aqueous methanol Journal of the American Chemical Society. 101: 3584-3587. DOI: 10.1021/ja00507a024  0.01
1979 SWAIN CG, POWELL AL, LYNCH TJ, ALPHA SR, DUNLAP RP. ChemInform Abstract: REDUCTION OF BENZALDEHYDE BY METHOXIDE ION IN AQUEOUS METHANOL Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197940135  0.01
1978 Wallace RW, Lynch TJ, Tallant EA, Cheung WY. An endogenous inhibitor protein of brain adenylate cyclase and cyclic nucleotide phosphodiesterase. Archives of Biochemistry and Biophysics. 187: 328-34. PMID 208465  0.01
1973 Lynch TJ, Henney HR. Carbohydrate metabolism in the plasmodium of the myxomycete Physarum flavicomum. Canadian Journal of Microbiology. 19: 803-10. PMID 4353806 DOI: 10.1139/m73-130  0.01
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