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Richard DeForest Palmiter, Ph.D. - Publications

Affiliations: 
Biochemistry University of Washington, Seattle, Seattle, WA 
Area:
neuropeptide signaling, receptor biology
Website:
http://depts.washington.edu/biowww/pages/faculty-Palmiter.shtml
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373 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Angelakos CC, Girven KS, Liu Y, Gonzalez OC, Murphy KR, Jennings KJ, Giardino WJ, Zweifel LS, Suko A, Palmiter RD, Clark SD, Krasnow MA, Bruchas MR, de Lecea L. A cluster of neuropeptide S neurons regulates breathing and arousal. Current Biology : Cb. PMID 38056461 DOI: 10.1016/j.cub.2023.11.018  0.689
2023 Machuca-Márquez P, Sánchez-Benito L, Menardy F, Urpi A, Girona M, Puighermanal E, Appiah I, Palmiter RD, Sanz E, Quintana A. Vestibular CCK signaling drives motion sickness-like behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304933120. PMID 37847729 DOI: 10.1073/pnas.2304933120  0.774
2023 Machado N, Raffin F, Kaur S, Banks A, Lynch N, Fanari O, Plascencia O, Aten S, Lima J, Bandaru S, Palmiter R, Arrigoni E, Saper C. Prolonged activation of EP3 receptor-expressing preoptic neurons underlies torpor responses. Research Square. PMID 37205518 DOI: 10.21203/rs.3.rs-2861253/v1  0.307
2023 Zagmutt S, Mera P, González-García I, Ibeas K, Romero MDM, Obri A, Martin B, Esteve-Codina A, Soler-Vázquez MC, Bastias-Pérez M, Cañes L, Augé E, Pelegri C, Vilaplana J, Ariza X, ... ... Palmiter R, et al. CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst. Biology of Sex Differences. 14: 14. PMID 36966335 DOI: 10.1186/s13293-023-00498-8  0.744
2023 Kim DI, Park S, Ye M, Chen JY, Jhang J, Hunker AC, Zweifel LS, Palmiter RD, Han S. Novel genetically encoded tools for imaging or silencing neuropeptide release from presynaptic terminals . Biorxiv : the Preprint Server For Biology. PMID 36712060 DOI: 10.1101/2023.01.19.524797  0.764
2022 Pauli JL, Chen JY, Basiri ML, Park S, Carter ME, Sanz E, McKnight GS, Stuber GD, Palmiter RD. Molecular and anatomical characterization of parabrachial neurons and their axonal projections. Elife. 11. PMID 36317965 DOI: 10.7554/eLife.81868  0.781
2021 Mogul AS, Hadley CK, Province HS, Pauli J, Gavrilova O, Xiao C, Palmiter RD, Piñol RA, Reitman ML. recombinase driver mice reveal lineage-dependent and -independent expression of in the mouse brain. Eneuro. PMID 34326065 DOI: 10.1523/ENEURO.0252-21.2021  0.371
2021 Liu S, Kim DI, Oh TG, Pao GM, Kim JH, Palmiter RD, Banghart MR, Lee KF, Evans RM, Han S. Neural basis of opioid-induced respiratory depression and its rescue. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074761 DOI: 10.1073/pnas.2022134118  0.631
2021 Hagihara KM, Bukalo O, Zeller M, Aksoy-Aksel A, Karalis N, Limoges A, Rigg T, Campbell T, Mendez A, Weinholtz C, Mahn M, Zweifel LS, Palmiter RD, Ehrlich I, Lüthi A, et al. Intercalated amygdala clusters orchestrate a switch in fear state. Nature. PMID 34040259 DOI: 10.1038/s41586-021-03593-1  0.571
2021 Xia G, Han Y, Meng F, He Y, Srisai D, Farias M, Dang M, Palmiter RD, Xu Y, Wu Q. Reciprocal control of obesity and anxiety-depressive disorder via a GABA and serotonin neural circuit. Molecular Psychiatry. PMID 33767348 DOI: 10.1038/s41380-021-01053-w  0.339
2021 Jarvie BC, Chen JY, King HO, Palmiter RD. Satb2 neurons in the parabrachial nucleus mediate taste perception. Nature Communications. 12: 224. PMID 33431851 DOI: 10.1038/s41467-020-20100-8  0.78
2020 Sanchis P, Fernández-Gayol O, Comes G, Aguilar K, Escrig A, Giralt M, Palmiter RD, Hidalgo J. A new mouse model to study restoration of interleukin-6 (IL-6) expression in a Cre-dependent manner: microglial IL-6 regulation of experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 17: 304. PMID 33059703 DOI: 10.1186/s12974-020-01969-0  0.447
2020 Ewbank SN, Campos CA, Chen JY, Bowen AJ, Padilla SL, Dempsey JL, Cui JY, Palmiter RD. Chronic G signaling in AgRP neurons does not cause obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32764144 DOI: 10.1073/Pnas.2004941117  0.656
2020 Bloodgood DW, Hardaway JA, Stanhope CM, Pati D, Pina MM, Neira S, Desai S, Boyt KM, Palmiter RD, Kash TL. Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake. Molecular Psychiatry. PMID 32099099 DOI: 10.1038/S41380-020-0690-Z  0.321
2020 Sanchis P, Fernández-Gayol O, Comes G, Escrig A, Giralt M, Palmiter RD, Hidalgo J. Interleukin-6 Derived from the Central Nervous System May Influence the Pathogenesis of Experimental Autoimmune Encephalomyelitis in a Cell-Dependent Manner. Cells. 9. PMID 32023844 DOI: 10.3390/Cells9020330  0.523
2020 Bowen AJ, Chen JY, Huang YW, Baertsch NA, Park S, Palmiter RD. Author response: Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons Elife. DOI: 10.7554/Elife.59799.Sa2  0.312
2019 Heymann G, Jo YS, Reichard KL, McFarland N, Chavkin C, Palmiter RD, Soden ME, Zweifel LS. Synergy of Distinct Dopamine Projection Populations in Behavioral Reinforcement. Neuron. PMID 31879163 DOI: 10.1016/J.Neuron.2019.11.024  0.669
2019 Zhang Z, Zhong P, Hu F, Barger Z, Ren Y, Ding X, Li S, Weber F, Chung S, Palmiter RD, Dan Y. An Excitatory Circuit in the Perioculomotor Midbrain for Non-REM Sleep Control. Cell. PMID 31031008 DOI: 10.1016/J.Cell.2019.03.041  0.309
2019 Padilla SL, Perez JG, Ben-Hamo M, Johnson CW, Sanchez REA, Bussi IL, Palmiter RD, de la Iglesia HO. Kisspeptin Neurons in the Arcuate Nucleus of the Hypothalamus Orchestrate Circadian Rhythms and Metabolism. Current Biology : Cb. PMID 30744968 DOI: 10.1016/J.Cub.2019.01.022  0.775
2018 Fergani C, Leon S, Padilla SL, Verstegen AM, Palmiter RD, Navarro VM. NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice. Elife. 7. PMID 30565563 DOI: 10.7554/Elife.40476  0.669
2018 Chen JY, Campos CA, Jarvie BC, Palmiter RD. Parabrachial CGRP Neurons Establish and Sustain Aversive Taste Memories. Neuron. PMID 30344042 DOI: 10.1016/j.neuron.2018.09.032  0.783
2018 Melief EJ, McKinley JW, Lam JY, Whiteley NM, Gibson AW, Neumaier JF, Henschen CW, Palmiter RD, Bamford NS, Darvas M. Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors. Npj Parkinson's Disease. 4: 23. PMID 30083593 DOI: 10.1038/S41531-018-0060-6  0.769
2018 Qiu J, Rivera HM, Bosch MA, Padilla SL, Stincic TL, Palmiter RD, Kelly MJ, Rønnekleiv OK. Estrogenic-dependent glutamatergic neurotransmission from kisspeptin neurons governs feeding circuits in females. Elife. 7. PMID 30079889 DOI: 10.7554/Elife.35656  0.676
2018 Padilla SL, Johnson CW, Barker FD, Patterson MA, Palmiter RD. A Neural Circuit Underlying the Generation of Hot Flushes. Cell Reports. 24: 271-277. PMID 29996088 DOI: 10.1016/J.Celrep.2018.06.037  0.747
2018 Palmiter RD. The Parabrachial Nucleus: CGRP Neurons Function as a General Alarm. Trends in Neurosciences. 41: 280-293. PMID 29703377 DOI: 10.1016/j.tins.2018.03.007  0.408
2018 Campos CA, Bowen AJ, Roman CW, Palmiter RD. Encoding of danger by parabrachial CGRP neurons. Nature. PMID 29562230 DOI: 10.1038/nature25511  0.414
2018 Qiu J, Rivera HM, Bosch MA, Padilla SL, Stincic TL, Palmiter RD, Kelly MJ, Rønnekleiv OK. Author response: Estrogenic-dependent glutamatergic neurotransmission from kisspeptin neurons governs feeding circuits in females Elife. DOI: 10.7554/Elife.35656.036  0.637
2017 Ryan PJ, Ross SI, Campos CA, Derkach VA, Palmiter RD. Oxytocin-receptor-expressing neurons in the parabrachial nucleus regulate fluid intake. Nature Neuroscience. 20: 1722-1733. PMID 29184212 DOI: 10.1038/s41593-017-0014-z  0.391
2017 Chen B, Hui J, Montgomery KS, Gella A, Bolea I, Sanz E, Palmiter RD, Quintana A. Loss of Mitochondrial Ndufs4 in Striatal Medium Spiny Neurons Mediates Progressive Motor Impairment in a Mouse Model of Leigh Syndrome. Frontiers in Molecular Neuroscience. 10: 265. PMID 28883788 DOI: 10.3389/Fnmol.2017.00265  0.78
2017 Rainwater A, Sanz E, Palmiter RD, Quintana A. Striatal GPR88 modulates foraging efficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28729439 DOI: 10.1523/Jneurosci.2439-16.2017  0.801
2017 Roman CW, Sloat SR, Palmiter RD. A tale of two circuits: CCK(NTS) neuron stimulation controls appetite and induces opposing motivational states by projections to distinct brain regions. Neuroscience. PMID 28684275 DOI: 10.1016/j.neuroscience.2017.06.049  0.355
2017 Campos CA, Bowen AJ, Han S, Wisse BE, Palmiter RD, Schwartz MW. Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus. Nature Neuroscience. PMID 28581479 DOI: 10.1038/Nn.4574  0.504
2017 Denis RG, Joly-Amado A, Webber E, Langlet F, Schaeffer M, Padilla SL, Cansell C, Dehouck B, Castel J, Delbès AS, Martinez S, Lacombe A, Rouch C, Kassis N, Fehrentz JA, ... ... Palmiter RD, et al. Palatability Can Drive Feeding Independent of AgRP Neurons. Cell Metabolism. 25: 975. PMID 28380385 DOI: 10.1016/J.Cmet.2017.03.001  0.8
2017 Choi WS, Kim HW, Tronche F, Palmiter RD, Storm DR, Xia Z. Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons. Scientific Reports. 7: 44989. PMID 28327638 DOI: 10.1038/Srep44989  0.423
2017 Padilla SL, Qiu J, Nestor CC, Zhang C, Smith AW, Whiddon BB, Rønnekleiv OK, Kelly MJ, Palmiter RD. AgRP to Kiss1 neuron signaling links nutritional state and fertility. Proceedings of the National Academy of Sciences of the United States of America. PMID 28196880 DOI: 10.1073/Pnas.1621065114  0.805
2016 Palmiter RD. Fast-acting neurons that suppress appetite. Nature Neuroscience. 20: 2-4. PMID 28025984 DOI: 10.1038/nn.4456  0.417
2016 Sanford CA, Soden ME, Baird MA, Miller SM, Schulkin J, Palmiter RD, Clark M, Zweifel LS. A Central Amygdala CRF Circuit Facilitates Learning about Weak Threats. Neuron. PMID 28017470 DOI: 10.1016/J.Neuron.2016.11.034  0.644
2016 Jarvie BC, Palmiter RD. HSD2 neurons in the hindbrain drive sodium appetite. Nature Neuroscience. PMID 27918529 DOI: 10.1038/nn.4451  0.795
2016 Qiu J, Nestor CC, Zhang C, Padilla SL, Palmiter RD, Kelly MJ, Rønnekleiv OK. High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons. Elife. 5. PMID 27549338 DOI: 10.7554/Elife.16246  0.671
2016 Roman CW, Derkach VA, Palmiter RD. Genetically and functionally defined NTS to PBN brain circuits mediating anorexia. Nature Communications. 7: 11905. PMID 27301688 DOI: 10.1038/ncomms11905  0.317
2016 Campos CA, Bowen AJ, Schwartz MW, Palmiter RD. Parabrachial CGRP Neurons Control Meal Termination. Cell Metabolism. 23: 811-20. PMID 27166945 DOI: 10.1016/J.Cmet.2016.04.006  0.317
2016 Nestor CC, Qiu J, Padilla SL, Zhang C, Bosch MA, Fan W, Aicher SA, Palmiter RD, Rønnekleiv OK, Kelly MJ. Optogenetic stimulation of arcuate nucleus Kiss1 neurons reveals a steroid-dependent glutamatergic input to POMC and AgRP neurons in male mice. Molecular Endocrinology (Baltimore, Md.). me20161026. PMID 27093227 DOI: 10.1210/Me.2016-1026  0.659
2016 Padilla SL, Qiu J, Soden ME, Sanz E, Nestor CC, Barker FD, Quintana A, Zweifel LS, Rønnekleiv OK, Kelly MJ, Palmiter RD. Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nature Neuroscience. PMID 27019015 DOI: 10.1038/Nn.4274  0.799
2016 Melief EJ, Gibbs JT, Li X, Morgan RG, Keene CD, Montine TJ, Palmiter RD, Darvas M. Characterization of cognitive impairments and neurotransmitter changes in a novel transgenic mouse lacking Slc10a4. Neuroscience. PMID 27001174 DOI: 10.1016/J.Neuroscience.2016.03.037  0.666
2016 Meng F, Han Y, Srisai D, Belakhov V, Farias M, Xu Y, Palmiter RD, Baasov T, Wu Q. New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976589 DOI: 10.1073/Pnas.1602049113  0.399
2016 Qiu J, Nestor CC, Zhang C, Padilla SL, Palmiter RD, Kelly MJ, Rønnekleiv OK. Author response: High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons Elife. DOI: 10.7554/Elife.16246.016  0.642
2015 Chen X, Luo J, Leng Y, Yang Y, Zweifel LS, Palmiter RD, Storm DR. Ablation of Type III Adenylyl Cyclase in Mice Causes Reduced Neuronal Activity, Altered Sleep Pattern, and Depression-like Phenotypes. Biological Psychiatry. PMID 26868444 DOI: 10.1016/J.Biopsych.2015.12.012  0.593
2015 Piroli GG, Manuel AM, Clapper AC, Walla MD, Baatz JE, Palmiter RD, Quintana A, Frizzell N. Succination is increased on select proteins in the brainstem of the Ndufs4 knockout mouse, a model of Leigh syndrome. Molecular & Cellular Proteomics : McP. PMID 26450614 DOI: 10.1074/Mcp.M115.051516  0.491
2015 Denis RG, Joly-Amado A, Webber E, Langlet F, Schaeffer M, Padilla SL, Cansell C, Dehouck B, Castel J, Delbès AS, Martinez S, Lacombe A, Rouch C, Kassis N, Fehrentz JA, ... ... Palmiter RD, et al. Palatability Can Drive Feeding Independent of AgRP Neurons. Cell Metabolism. PMID 26278050 DOI: 10.1016/J.Cmet.2015.07.011  0.811
2015 Han S, Soleiman MT, Soden ME, Zweifel LS, Palmiter RD. Elucidating an Affective Pain Circuit that Creates a Threat Memory. Cell. 162: 363-74. PMID 26186190 DOI: 10.1016/J.Cell.2015.05.057  0.776
2015 Garrett Morgan R, Gibbs JT, Melief EJ, Postupna NO, Sherfield EE, Wilson A, Dirk Keene C, Montine TJ, Palmiter RD, Darvas M. Relative contributions of severe dopaminergic neuron ablation and dopamine depletion to cognitive impairment. Experimental Neurology. 271: 205-214. PMID 26079646 DOI: 10.1016/J.Expneurol.2015.06.013  0.677
2015 Kim HW, Choi WS, Sorscher N, Park HJ, Tronche F, Palmiter RD, Xia Z. Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo. Neurobiology of Aging. PMID 26070241 DOI: 10.1016/J.Neurobiolaging.2015.05.008  0.353
2015 Sanz E, Quintana A, Deem JD, Steiner RA, Palmiter RD, McKnight GS. Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5549-56. PMID 25855171 DOI: 10.1523/Jneurosci.3614-14.2015  0.799
2015 Carter ME, Han S, Palmiter RD. Parabrachial calcitonin gene-related peptide neurons mediate conditioned taste aversion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4582-6. PMID 25788675 DOI: 10.1523/Jneurosci.3729-14.2015  0.652
2015 Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B. The paraventricular thalamus controls a central amygdala fear circuit. Nature. 519: 455-9. PMID 25600269 DOI: 10.1038/Nature13978  0.682
2015 Darvas M, Palmiter RD. Specific contributions of N-methyl-D-aspartate receptors in the dorsal striatum to cognitive flexibility. Neuroscience. 284: 934-42. PMID 25446363 DOI: 10.1016/J.Neuroscience.2014.11.011  0.663
2015 Piroli' GG, Capps' AC, Manuel' AM, Baatz JE, Palmiter RD, Quintana A, Frizzell N. Protein Succination Is Increased in a Model of Leigh Syndrome Free Radical Biology and Medicine. 87: S32. DOI: 10.1016/J.Freeradbiomed.2015.10.086  0.481
2015 Han S, Soleiman M, Soden M, Zweifel L, Palmiter RD. Elucidating an Affective Pain Circuit that Creates a Threat Memory Cell. 162: 363-374. DOI: 10.1016/j.cell.2015.05.057  0.752
2015 Chen X, Luo J, Leng Y, Yang Y, Zweifel LS, Palmiter RD, Storm DR. Ablation of Type III Adenylyl Cyclase in Mice Causes Reduced Neuronal Activity, Altered Sleep Pattern, and Depression-like Phenotypes Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.12.012  0.616
2014 Gallardo CM, Darvas M, Oviatt M, Chang CH, Michalik M, Huddy TF, Meyer EE, Shuster SA, Aguayo A, Hill EM, Kiani K, Ikpeazu J, Martinez JS, Purpura M, Smit AN, ... ... Palmiter RD, et al. Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice. Elife. 3: e03781. PMID 25217530 DOI: 10.7554/Elife.03781  0.701
2014 Naydenov AV, Sepers MD, Swinney K, Raymond LA, Palmiter RD, Stella N. Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice. Neurobiology of Disease. 71: 140-50. PMID 25134728 DOI: 10.1016/J.Nbd.2014.08.009  0.384
2014 Darvas M, Wunsch AM, Gibbs JT, Palmiter RD. Dopamine dependency for acquisition and performance of Pavlovian conditioned response. Proceedings of the National Academy of Sciences of the United States of America. 111: 2764-9. PMID 24550305 DOI: 10.1073/Pnas.1400332111  0.679
2014 Darvas M, Henschen CW, Palmiter RD. Contributions of signaling by dopamine neurons in dorsal striatum to cognitive behaviors corresponding to those observed in Parkinson's disease. Neurobiology of Disease. 65: 112-23. PMID 24491966 DOI: 10.1016/J.Nbd.2014.01.017  0.654
2014 Gallardo CM, Darvas M, Oviatt M, Chang CH, Michalik M, Huddy TF, Meyer EE, Shuster SA, Aguayo A, Hill EM, Kiani K, Ikpeazu J, Martinez JS, Purpura M, Smit AN, ... ... Palmiter RD, et al. Author response: Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice Elife. DOI: 10.7554/Elife.03781.023  0.712
2013 Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, et al. mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science (New York, N.Y.). 342: 1524-8. PMID 24231806 DOI: 10.1126/Science.1244360  0.522
2013 Carter ME, Soden ME, Zweifel LS, Palmiter RD. Genetic identification of a neural circuit that suppresses appetite. Nature. 503: 111-4. PMID 24121436 DOI: 10.1038/Nature12596  0.762
2013 Wu Q, Zheng R, Srisai D, McKnight GS, Palmiter RD. NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus. Proceedings of the National Academy of Sciences of the United States of America. 110: 14765-70. PMID 23964123 DOI: 10.1073/Pnas.1314137110  0.512
2013 Henschen CW, Palmiter RD, Darvas M. Restoration of dopamine signaling to the dorsal striatum is sufficient for aspects of active maternal behavior in female mice. Endocrinology. 154: 4316-27. PMID 23959937 DOI: 10.1210/En.2013-1257  0.664
2013 Wang W, Darvas M, Storey GP, Bamford IJ, Gibbs JT, Palmiter RD, Bamford NS. Acetylcholine encodes long-lasting presynaptic plasticity at glutamatergic synapses in the dorsal striatum after repeated amphetamine exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10405-26. PMID 23785153 DOI: 10.1523/Jneurosci.0014-13.2013  0.684
2013 Popa SM, Moriyama RM, Caligioni CS, Yang JJ, Cho CM, Concepcion TL, Oakley AE, Lee IH, Sanz E, Amieux PS, Caraty A, Palmiter RD, Navarro VM, Chan YM, Seminara SB, et al. Redundancy in Kiss1 expression safeguards reproduction in the mouse. Endocrinology. 154: 2784-94. PMID 23736293 DOI: 10.1210/En.2013-1222  0.82
2013 Eldred KC, Palmiter RD. Amphetamine-induced sensitization has little effect on multiple learning paradigms and fails to rescue mice with a striatal learning defect. Plos One. 8: e59964. PMID 23596507 DOI: 10.1371/journal.pone.0059964  0.366
2013 Whiddon BB, Palmiter RD. Ablation of neurons expressing melanin-concentrating hormone (MCH) in adult mice improves glucose tolerance independent of MCH signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2009-16. PMID 23365238 DOI: 10.1523/Jneurosci.3921-12.2013  0.833
2013 Arnett AL, Beutler LR, Quintana A, Allen J, Finn E, Palmiter RD, Chamberlain JS. Heparin-binding correlates with increased efficiency of AAV1- and AAV6-mediated transduction of striated muscle, but negatively impacts CNS transduction. Gene Therapy. 20: 497-503. PMID 22855092 DOI: 10.1038/Gt.2012.60  0.653
2013 Darvas M, Palmiter RD. Contributions of Dopamine in the Dorsal Striatum to Behaviors Corresponding to Cognitive Dysfunction in Parkinson's Disease Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 132. DOI: 10.1016/B978-0-12-800044-1.00116-1  0.593
2012 Golub JS, Tong L, Ngyuen TB, Hume CR, Palmiter RD, Rubel EW, Stone JS. Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15093-105. PMID 23100430 DOI: 10.1523/JNEUROSCI.1709-12.2012  0.314
2012 Quintana A, Sanz E, Wang W, Storey GP, Güler AD, Wanat MJ, Roller BA, La Torre A, Amieux PS, McKnight GS, Bamford NS, Palmiter RD. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nature Neuroscience. 15: 1547-55. PMID 23064379 DOI: 10.1038/Nn.3239  0.806
2012 Quintana A, Morgan PG, Kruse SE, Palmiter RD, Sedensky MM. Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I. Plos One. 7: e42904. PMID 22912761 DOI: 10.1371/Journal.Pone.0042904  0.601
2012 Palmiter RD. New game for hunger neurons. Nature Neuroscience. 15: 1060-1. PMID 22837033 DOI: 10.1038/nn.3167  0.405
2012 Jackson CR, Ruan GX, Aseem F, Abey J, Gamble K, Stanwood G, Palmiter RD, Iuvone PM, McMahon DG. Retinal dopamine mediates multiple dimensions of light-adapted vision. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9359-68. PMID 22764243 DOI: 10.1523/Jneurosci.0711-12.2012  0.319
2012 Quintana A, Zanella S, Koch H, Kruse SE, Lee D, Ramirez JM, Palmiter RD. Fatal breathing dysfunction in a mouse model of Leigh syndrome. The Journal of Clinical Investigation. 122: 2359-68. PMID 22653057 DOI: 10.1172/Jci62923  0.587
2012 Güler AD, Rainwater A, Parker JG, Jones GL, Argilli E, Arenkiel BR, Ehlers MD, Bonci A, Zweifel LS, Palmiter RD. Transient activation of specific neurons in mice by selective expression of the capsaicin receptor. Nature Communications. 3: 746. PMID 22434189 DOI: 10.1038/Ncomms1749  0.819
2012 Wu Q, Clark MS, Palmiter RD. Deciphering a neuronal circuit that mediates appetite. Nature. 483: 594-7. PMID 22419158 DOI: 10.1038/Nature10899  0.426
2012 Wu Q, Whiddon BB, Palmiter RD. Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertility. Proceedings of the National Academy of Sciences of the United States of America. 109: 3155-60. PMID 22232663 DOI: 10.1073/Pnas.1120501109  0.823
2012 Morgan PG, Quintana A, Palmiter RD, Sedensky MM. Specific hypersensitivity to volatile anesthetics in a mouse lacking Ndufs4, a subunit of mitochondrial complex I Mitochondrion. 12: 566-567. DOI: 10.1016/J.Mito.2012.07.043  0.502
2011 Beutler LR, Eldred KC, Quintana A, Keene CD, Rose SE, Postupna N, Montine TJ, Palmiter RD. Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons. Plos One. 6: e28168. PMID 22132236 DOI: 10.1371/Journal.Pone.0028168  0.73
2011 Parker JG, Wanat MJ, Soden ME, Ahmad K, Zweifel LS, Bamford NS, Palmiter RD. Attenuating GABA(A) receptor signaling in dopamine neurons selectively enhances reward learning and alters risk preference in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17103-12. PMID 22114279 DOI: 10.1523/Jneurosci.1715-11.2011  0.796
2011 Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, Kelly MJ, Rønnekleiv OK, Sanz E, McKnight GS, Clifton DK, Palmiter RD, Steiner RA. Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology. 152: 4298-309. PMID 21933870 DOI: 10.1210/En.2011-1521  0.782
2011 Navarro VM, Gottsch ML, Wu M, García-Galiano D, Hobbs SJ, Bosch MA, Pinilla L, Clifton DK, Dearth A, Ronnekleiv OK, Braun RE, Palmiter RD, Tena-Sempere M, Alreja M, Steiner RA. Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse. Endocrinology. 152: 4265-75. PMID 21914775 DOI: 10.1210/En.2011-1143  0.701
2011 Palmiter RD. Dopamine signaling as a neural correlate of consciousness. Neuroscience. 198: 213-20. PMID 21839810 DOI: 10.1016/j.neuroscience.2011.06.089  0.445
2011 Bruchas MR, Schindler AG, Shankar H, Messinger DI, Miyatake M, Land BB, Lemos JC, Hagan CE, Neumaier JF, Quintana A, Palmiter RD, Chavkin C. Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction. Neuron. 71: 498-511. PMID 21835346 DOI: 10.1016/J.Neuron.2011.06.011  0.718
2011 Parker JG, Beutler LR, Palmiter RD. The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11362-9. PMID 21813695 DOI: 10.1523/Jneurosci.2411-11.2011  0.753
2011 Zweifel LS, Fadok JP, Argilli E, Garelick MG, Jones GL, Dickerson TM, Allen JM, Mizumori SJ, Bonci A, Palmiter RD. Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety. Nature Neuroscience. 14: 620-6. PMID 21499253 DOI: 10.1038/Nn.2808  0.818
2011 Choi WS, Palmiter RD, Xia Z. Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. The Journal of Cell Biology. 192: 873-82. PMID 21383081 DOI: 10.1083/Jcb.201009132  0.41
2011 Beutler LR, Wanat MJ, Quintana A, Sanz E, Bamford NS, Zweifel LS, Palmiter RD. Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization. Proceedings of the National Academy of Sciences of the United States of America. 108: 4206-11. PMID 21368124 DOI: 10.1073/Pnas.1101424108  0.819
2011 Darvas M, Fadok JP, Palmiter RD. Requirement of dopamine signaling in the amygdala and striatum for learning and maintenance of a conditioned avoidance response. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 136-43. PMID 21325435 DOI: 10.1101/Lm.2041211  0.81
2011 Sindreu C, Palmiter RD, Storm DR. Zinc transporter ZnT-3 regulates presynaptic Erk1/2 signaling and hippocampus-dependent memory. Proceedings of the National Academy of Sciences of the United States of America. 108: 3366-70. PMID 21245308 DOI: 10.1073/pnas.1019166108  0.782
2011 Wu Q, Palmiter RD. GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism. European Journal of Pharmacology. 660: 21-7. PMID 21211531 DOI: 10.1016/J.Ejphar.2010.10.110  0.514
2011 Darvas M, Palmiter RD. Contributions of striatal dopamine signaling to the modulation of cognitive flexibility. Biological Psychiatry. 69: 704-7. PMID 21074144 DOI: 10.1016/J.Biopsych.2010.09.033  0.665
2011 Wall VZ, Parker JG, Fadok JP, Darvas M, Zweifel L, Palmiter RD. A behavioral genetics approach to understanding D1 receptor involvement in phasic dopamine signaling. Molecular and Cellular Neurosciences. 46: 21-31. PMID 20888914 DOI: 10.1016/J.Mcn.2010.09.011  0.815
2010 Fadok JP, Darvas M, Dickerson TM, Palmiter RD. Long-term memory for pavlovian fear conditioning requires dopamine in the nucleus accumbens and basolateral amygdala. Plos One. 5: e12751. PMID 20856811 DOI: 10.1371/Journal.Pone.0012751  0.804
2010 Parker JG, Zweifel LS, Clark JJ, Evans SB, Phillips PE, Palmiter RD. Absence of NMDA receptors in dopamine neurons attenuates dopamine release but not conditioned approach during Pavlovian conditioning. Proceedings of the National Academy of Sciences of the United States of America. 107: 13491-6. PMID 20616081 DOI: 10.1073/Pnas.1007827107  0.793
2010 Quintana A, Kruse SE, Kapur RP, Sanz E, Palmiter RD. Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome. Proceedings of the National Academy of Sciences of the United States of America. 107: 10996-1001. PMID 20534480 DOI: 10.1073/Pnas.1006214107  0.791
2010 Yuan J, Darvas M, Sotak B, Hatzidimitriou G, McCann UD, Palmiter RD, Ricaurte GA. Dopamine is not essential for the development of methamphetamine-induced neurotoxicity. Journal of Neurochemistry. 114: 1135-42. PMID 20533999 DOI: 10.1111/J.1471-4159.2010.06839.X  0.667
2010 Hnasko TS, Chuhma N, Zhang H, Goh GY, Sulzer D, Palmiter RD, Rayport S, Edwards RH. Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron. 65: 643-56. PMID 20223200 DOI: 10.1016/J.Neuron.2010.02.012  0.73
2010 Darvas M, Palmiter RD. Restricting dopaminergic signaling to either dorsolateral or medial striatum facilitates cognition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1158-65. PMID 20089924 DOI: 10.1523/Jneurosci.4576-09.2010  0.679
2010 Madisen L, Zwingman TA, Sunkin SM, Oh SW, Zariwala HA, Gu H, Ng LL, Palmiter RD, Hawrylycz MJ, Jones AR, Lein ES, Zeng H. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nature Neuroscience. 13: 133-40. PMID 20023653 DOI: 10.1038/Nn.2467  0.402
2009 Land BB, Bruchas MR, Schattauer S, Giardino WJ, Aita M, Messinger D, Hnasko TS, Palmiter RD, Chavkin C. Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking. Proceedings of the National Academy of Sciences of the United States of America. 106: 19168-73. PMID 19864633 DOI: 10.1073/Pnas.0910705106  0.707
2009 Fadok JP, Dickerson TM, Palmiter RD. Dopamine is necessary for cue-dependent fear conditioning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11089-97. PMID 19741115 DOI: 10.1523/Jneurosci.1616-09.2009  0.761
2009 Darvas M, Palmiter RD. Restriction of dopamine signaling to the dorsolateral striatum is sufficient for many cognitive behaviors. Proceedings of the National Academy of Sciences of the United States of America. 106: 14664-9. PMID 19667174 DOI: 10.1073/Pnas.0907299106  0.685
2009 Wu Q, Boyle MP, Palmiter RD. Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation. Cell. 137: 1225-34. PMID 19563755 DOI: 10.1016/J.Cell.2009.04.022  0.503
2009 Zweifel LS, Parker JG, Lobb CJ, Rainwater A, Wall VZ, Fadok JP, Darvas M, Kim MJ, Mizumori SJ, Paladini CA, Phillips PE, Palmiter RD. Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 7281-8. PMID 19342487 DOI: 10.1073/Pnas.0813415106  0.813
2008 Choi WS, Kruse SE, Palmiter RD, Xia Z. Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proceedings of the National Academy of Sciences of the United States of America. 105: 15136-41. PMID 18812510 DOI: 10.1073/Pnas.0807581105  0.393
2008 Wu Q, Howell MP, Palmiter RD. Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9218-26. PMID 18784302 DOI: 10.1523/Jneurosci.2449-08.2008  0.516
2008 Zweifel LS, Argilli E, Bonci A, Palmiter RD. Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron. 59: 486-96. PMID 18701073 DOI: 10.1016/J.Neuron.2008.05.028  0.735
2008 Neri C, Ghelardini C, Sotak B, Palmiter RD, Guarna M, Stefano G, Bianchi E. Dopamine is necessary to endogenous morphine formation in mammalian brain in vivo. Journal of Neurochemistry. 106: 2337-44. PMID 18643791 DOI: 10.1111/j.1471-4159.2008.05572.x  0.368
2008 Heusner CL, Beutler LR, Houser CR, Palmiter RD. Deletion of GAD67 in dopamine receptor-1 expressing cells causes specific motor deficits. Genesis (New York, N.Y. : 2000). 46: 357-67. PMID 18615733 DOI: 10.1002/Dvg.20405  0.817
2008 Palmiter RD. Dopamine signaling in the dorsal striatum is essential for motivated behaviors: lessons from dopamine-deficient mice. Annals of the New York Academy of Sciences. 1129: 35-46. PMID 18591467 DOI: 10.1196/annals.1417.003  0.435
2008 Kruse SE, Watt WC, Marcinek DJ, Kapur RP, Schenkman KA, Palmiter RD. Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy. Cell Metabolism. 7: 312-20. PMID 18396137 DOI: 10.1016/J.Cmet.2008.02.004  0.321
2008 Wu Q, Howell MP, Cowley MA, Palmiter RD. Starvation after AgRP neuron ablation is independent of melanocortin signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 2687-92. PMID 18272480 DOI: 10.1073/Pnas.0712062105  0.517
2008 Kim DS, Palmiter RD. Interaction of dopamine and adenosine receptor function in behavior: studies with dopamine-deficient mice. Frontiers in Bioscience : a Journal and Virtual Library. 13: 2311-8. PMID 17981713 DOI: 10.2741/2845  0.581
2008 Phillips CT, Palmiter RD. Role of agouti-related protein-expressing neurons in lactation. Endocrinology. 149: 544-50. PMID 17974621 DOI: 10.1210/en.2007-1153  0.426
2007 Hnasko TS, Sotak BN, Palmiter RD. Cocaine-conditioned place preference by dopamine-deficient mice is mediated by serotonin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12484-8. PMID 18003826 DOI: 10.1523/Jneurosci.3133-07.2007  0.699
2007 Hanahan D, Wagner EF, Palmiter RD. The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer. Genes & Development. 21: 2258-70. PMID 17875663 DOI: 10.1101/Gad.1583307  0.312
2007 Hnasko TS, Hnasko RM, Sotak BN, Kapur RP, Palmiter RD. Genetic disruption of dopamine production results in pituitary adenomas and severe prolactinemia. Neuroendocrinology. 86: 48-57. PMID 17622754 DOI: 10.1159/000105242  0.71
2007 Palmiter RD. Is dopamine a physiologically relevant mediator of feeding behavior? Trends in Neurosciences. 30: 375-81. PMID 17604133 DOI: 10.1016/j.tins.2007.06.004  0.421
2007 Robinson S, Rainwater AJ, Hnasko TS, Palmiter RD. Viral restoration of dopamine signaling to the dorsal striatum restores instrumental conditioning to dopamine-deficient mice. Psychopharmacology. 191: 567-78. PMID 17093978 DOI: 10.1007/S00213-006-0579-9  0.767
2006 Olson VG, Griner NB, Heusner CL, Palmiter RD. Lack of neuropeptide Y attenuates the somatic signs of opiate withdrawal. Synapse (New York, N.Y.). 60: 553-6. PMID 16952158 DOI: 10.1002/Syn.20328  0.777
2006 Hunsley MS, Curtis WR, Palmiter RD. Behavioral and sleep/wake characteristics of mice lacking norepinephrine and hypocretin. Genes, Brain, and Behavior. 5: 451-7. PMID 16923149 DOI: 10.1111/j.1601-183X.2005.00179.x  0.36
2006 Hnasko TS, Perez FA, Scouras AD, Stoll EA, Gale SD, Luquet S, Phillips PE, Kremer EJ, Palmiter RD. Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia. Proceedings of the National Academy of Sciences of the United States of America. 103: 8858-63. PMID 16723393 DOI: 10.1073/Pnas.0603081103  0.739
2006 Robinson S, Sotak BN, During MJ, Palmiter RD. Local dopamine production in the dorsal striatum restores goal-directed behavior in dopamine-deficient mice. Behavioral Neuroscience. 120: 196-200. PMID 16492130 DOI: 10.1037/0735-7044.120.1.000  0.696
2006 Olson VG, Heusner CL, Bland RJ, During MJ, Weinshenker D, Palmiter RD. Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward. Science (New York, N.Y.). 311: 1017-20. PMID 16484499 DOI: 10.1126/Science.1119311  0.803
2006 Kim DS, Palmiter RD, Cummins A, Gerfen CR. Reversal of supersensitive striatal dopamine D1 receptor signaling and extracellular signal-regulated kinase activity in dopamine-deficient mice. Neuroscience. 137: 1381-8. PMID 16388913 DOI: 10.1016/j.neuroscience.2005.10.054  0.587
2005 Perez FA, Curtis WR, Palmiter RD. Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity. Bmc Neuroscience. 6: 71. PMID 16375772 DOI: 10.1186/1471-2202-6-71  0.445
2005 Hnasko TS, Sotak BN, Palmiter RD. Morphine reward in dopamine-deficient mice. Nature. 438: 854-7. PMID 16341013 DOI: 10.1038/Nature04172  0.694
2005 Ste Marie L, Luquet S, Cole TB, Palmiter RD. Modulation of neuropeptide Y expression in adult mice does not affect feeding. Proceedings of the National Academy of Sciences of the United States of America. 102: 18632-7. PMID 16339312 DOI: 10.1073/Pnas.0509240102  0.612
2005 Luquet S, Perez FA, Hnasko TS, Palmiter RD. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science (New York, N.Y.). 310: 683-5. PMID 16254186 DOI: 10.1126/Science.1115524  0.716
2005 Sotak BN, Hnasko TS, Robinson S, Kremer EJ, Palmiter RD. Dysregulation of dopamine signaling in the dorsal striatum inhibits feeding. Brain Research. 1061: 88-96. PMID 16226228 DOI: 10.1016/J.Brainres.2005.08.053  0.748
2005 Ste Marie L, Luquet S, Curtis W, Palmiter RD. Norepinephrine- and epinephrine-deficient mice gain weight normally on a high-fat diet. Obesity Research. 13: 1518-22. PMID 16222052 DOI: 10.1038/oby.2005.185  0.356
2005 Hasbani DM, Perez FA, Palmiter RD, O'Malley KL. Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9428-33. PMID 16221852 DOI: 10.1523/Jneurosci.0130-05.2005  0.44
2005 Heusner CL, Palmiter RD. Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6651-7. PMID 16014726 DOI: 10.1523/Jneurosci.1474-05.2005  0.778
2005 Cannon CM, Scannell CA, Palmiter RD. Mice lacking dopamine D1 receptors express normal lithium chloride-induced conditioned taste aversion for salt but not sucrose. The European Journal of Neuroscience. 21: 2600-4. PMID 15932618 DOI: 10.1111/j.1460-9568.2005.04077.x  0.403
2005 Thiriet N, Deng X, Solinas M, Ladenheim B, Curtis W, Goldberg SR, Palmiter RD, Cadet JL. Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5273-9. PMID 15930374 DOI: 10.1523/Jneurosci.4893-04.2005  0.438
2005 Robinson S, Sandstrom SM, Denenberg VH, Palmiter RD. Distinguishing whether dopamine regulates liking, wanting, and/or learning about rewards. Behavioral Neuroscience. 119: 5-15. PMID 15727507 DOI: 10.1037/0735-7044.119.1.5  0.571
2005 Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, Grandy DK, Premont RT, Sotnikova TD, Boksa P, El-Ghundi M, O'dowd BF, George SR, Perreault ML, Männistö PT, Robinson S, ... Palmiter RD, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3513-8. PMID 15716360 DOI: 10.1073/Pnas.0409766102  0.666
2005 Chartoff EH, Heusner CL, Palmiter RD. Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1324-33. PMID 15688082 DOI: 10.1038/Sj.Npp.1300678  0.786
2005 Perez FA, Palmiter RD. Parkin-deficient mice are not a robust model of parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 102: 2174-9. PMID 15684050 DOI: 10.1073/pnas.0409598102  0.394
2004 Bamford NS, Robinson S, Palmiter RD, Joyce JA, Moore C, Meshul CK. Dopamine modulates release from corticostriatal terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9541-52. PMID 15509741 DOI: 10.1523/Jneurosci.2891-04.2004  0.605
2004 Cannon CM, Abdallah L, Tecott LH, During MJ, Palmiter RD. Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice. Neuron. 44: 509-20. PMID 15504330 DOI: 10.1016/j.neuron.2004.10.009  0.62
2004 Andrews GK, Wang H, Dey SK, Palmiter RD. Mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis (New York, N.Y. : 2000). 40: 74-81. PMID 15452870 DOI: 10.1002/Gene.20067  0.33
2004 Hnasko TS, Szczypka MS, Alaynick WA, During MJ, Palmiter RD. A role for dopamine in feeding responses produced by orexigenic agents. Brain Research. 1023: 309-18. PMID 15374756 DOI: 10.1016/J.Brainres.2004.07.051  0.813
2004 Chartoff EH, Szczypka MS, Palmiter RD, Dorsa DM. Endogenous neurotensin attenuates dopamine-dependent locomotion and stereotypy. Brain Research. 1022: 71-80. PMID 15353215 DOI: 10.1016/j.brainres.2004.06.061  0.409
2004 Robinson S, Smith DM, Mizumori SJ, Palmiter RD. Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor activation and anesthesia. Proceedings of the National Academy of Sciences of the United States of America. 101: 13329-34. PMID 15317940 DOI: 10.1073/Pnas.0405084101  0.609
2004 Szot P, Lester M, Laughlin ML, Palmiter RD, Liles LC, Weinshenker D. The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors. Neuroscience. 126: 795-803. PMID 15183527 DOI: 10.1016/J.Neuroscience.2004.04.030  0.591
2004 Sindelar DK, Ste Marie L, Miura GI, Palmiter RD, McMinn JE, Morton GJ, Schwartz MW. Neuropeptide Y is required for hyperphagic feeding in response to neuroglucopenia. Endocrinology. 145: 3363-8. PMID 15064281 DOI: 10.1210/En.2003-1727  0.357
2004 Friedlich AL, Lee JY, van Groen T, Cherny RA, Volitakis I, Cole TB, Palmiter RD, Koh JY, Bush AI. Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3453-9. PMID 15056725 DOI: 10.1523/Jneurosci.0297-04.2004  0.556
2004 Denenberg VH, Kim DS, Palmiter RD. The role of dopamine in learning, memory, and performance of a water escape task. Behavioural Brain Research. 148: 73-8. PMID 14684249 DOI: 10.1016/S0166-4328(03)00183-9  0.558
2004 Swoap SJ, Weinshenker D, Palmiter RD, Garber G. Dbh(-/-) mice are hypotensive, have altered circadian rhythms, and have abnormal responses to dieting and stress. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R108-13. PMID 12969876 DOI: 10.1152/Ajpregu.00405.2003  0.592
2003 Cannon CM, Palmiter RD. Reward without dopamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10827-31. PMID 14645475 DOI: 10.1523/Jneurosci.23-34-10827.2003  0.419
2003 Lee JY, Kim JH, Palmiter RD, Koh JY. Zinc released from metallothionein-iii may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury. Experimental Neurology. 184: 337-47. PMID 14637104 DOI: 10.1016/S0014-4886(03)00382-0  0.371
2003 Ste Marie L, Palmiter RD. Norepinephrine and epinephrine-deficient mice are hyperinsulinemic and have lower blood glucose. Endocrinology. 144: 4427-32. PMID 12959968 DOI: 10.1210/en.2003-0561  0.325
2003 Heusner CL, Hnasko TS, Szczypka MS, Liu Y, During MJ, Palmiter RD. Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain Research. 980: 266-74. PMID 12867267 DOI: 10.1016/S0006-8993(03)02986-X  0.81
2003 Ceballos D, Lago N, Verdú E, Penkowa M, Carrasco J, Navarro X, Palmiter RD, Hidalgo J. Role of metallothioneins in peripheral nerve function and regeneration. Cellular and Molecular Life Sciences : Cmls. 60: 1209-16. PMID 12861386 DOI: 10.1007/S00018-003-3047-2  0.537
2003 Carrasco J, Penkowa M, Giralt M, Camats J, Molinero A, Campbell IL, Palmiter RD, Hidalgo J. Role of metallothionein-III following central nervous system damage. Neurobiology of Disease. 13: 22-36. PMID 12758064 DOI: 10.1016/S0969-9961(03)00015-9  0.607
2003 Cannon CM, Palmiter RD. Peptides that regulate food intake: norepinephrine is not required for reduction of feeding induced by cholecystokinin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R1384-8. PMID 12736175 DOI: 10.1152/ajpregu.00689.2002  0.402
2003 Paladini CA, Robinson S, Morikawa H, Williams JT, Palmiter RD. Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proceedings of the National Academy of Sciences of the United States of America. 100: 2866-71. PMID 12604788 DOI: 10.1073/Pnas.0138018100  0.604
2003 Kim DS, Palmiter RD. Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 1346-51. PMID 12538862 DOI: 10.1073/pnas.252753799  0.582
2003 Lopantsev V, Wenzel HJ, Cole TB, Palmiter RD, Schwartzkroin PA. Lack of vesicular zinc in mossy fibers does not affect synaptic excitability of CA3 pyramidal cells in zinc transporter 3 knockout mice. Neuroscience. 116: 237-48. PMID 12535956 DOI: 10.1016/S0306-4522(02)00570-5  0.562
2002 Brot MD, Szczypka MS, Reavell R, Marck BT, Matsumoto AM, Palmiter RD. Neonatal 6-hydroxydopamine administration to mice is fatal. Developmental Neuroscience. 24: 531-8. PMID 12697991 DOI: 10.1159/000069364  0.425
2002 Kim DS, Froelick GJ, Palmiter RD. Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9841-9. PMID 12427840 DOI: 10.1523/Jneurosci.22-22-09841.2002  0.588
2002 Weinshenker D, Miller NS, Blizinsky K, Laughlin ML, Palmiter RD. Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals. Proceedings of the National Academy of Sciences of the United States of America. 99: 13873-7. PMID 12370425 DOI: 10.1073/Pnas.212519999  0.65
2002 Weinshenker D, White SS, Javors MA, Palmiter RD, Szot P. Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo. Brain Research. 946: 239-46. PMID 12137927 DOI: 10.1016/S0006-8993(02)02889-5  0.626
2002 Lee JY, Cole TB, Palmiter RD, Suh SW, Koh JY. Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 7705-10. PMID 12032347 DOI: 10.1073/Pnas.092034699  0.576
2002 Laybutt DR, Weir GC, Kaneto H, Lebet J, Palmiter RD, Sharma A, Bonner-Weir S. Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes. Diabetes. 51: 1793-804. PMID 12031967 DOI: 10.2337/Diabetes.51.6.1793  0.334
2002 Pralong FP, Gonzales C, Voirol MJ, Palmiter RD, Brunner HR, Gaillard RC, Seydoux J, Pedrazzini T. The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 712-4. PMID 11978737 DOI: 10.1096/fj.01-0754fje  0.336
2002 Sindelar DK, Mystkowski P, Marsh DJ, Palmiter RD, Schwartz MW. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. 51: 778-83. PMID 11872679 DOI: 10.2337/Diabetes.51.3.778  0.343
2002 Jasmin L, Tien D, Weinshenker D, Palmiter RD, Green PG, Janni G, Ohara PT. The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proceedings of the National Academy of Sciences of the United States of America. 99: 1029-34. PMID 11805341 DOI: 10.1073/Pnas.012598599  0.584
2002 Guo H, Castro PA, Palmiter RD, Baraban SC. Y5 receptors mediate neuropeptide Y actions at excitatory synapses in area CA3 of the mouse hippocampus. Journal of Neurophysiology. 87: 558-66. PMID 11784771 DOI: 10.1152/Jn.00532.2001  0.367
2001 Weinshenker D, Szot P, Miller NS, Rust NC, Hohmann JG, Pyati U, White SS, Palmiter RD. Genetic comparison of seizure control by norepinephrine and neuropeptide Y. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7764-9. PMID 11567066 DOI: 10.1523/Jneurosci.21-19-07764.2001  0.565
2001 Chartoff EH, Marck BT, Matsumoto AM, Dorsa DM, Palmiter RD. Induction of stereotypy in dopamine-deficient mice requires striatal D1 receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 98: 10451-6. PMID 11517332 DOI: 10.1073/pnas.181356498  0.425
2001 Weinshenker D, Szot P, Miller NS, Palmiter RD. Alpha(1) and beta(2) adrenoreceptor agonists inhibit pentylenetetrazole-induced seizures in mice lacking norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 298: 1042-8. PMID 11504801  0.52
2001 Szczypka MS, Kwok K, Brot MD, Marck BT, Matsumoto AM, Donahue BA, Palmiter RD. Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice. Neuron. 30: 819-28. PMID 11430814 DOI: 10.1016/S0896-6273(01)00319-1  0.448
2001 Di Marzo V, Goparaju SK, Wang L, Liu J, Bátkai S, Járai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature. 410: 822-5. PMID 11298451 DOI: 10.1038/35071088  0.339
2001 Cole TB, Martyanova A, Palmiter RD. Removing zinc from synaptic vesicles does not impair spatial learning, memory, or sensorimotor functions in the mouse. Brain Research. 891: 253-65. PMID 11164830 DOI: 10.1016/S0006-8993(00)03220-0  0.554
2000 Thiele TE, Miura GI, Marsh DJ, Bernstein IL, Palmiter RD. Neurobiological responses to ethanol in mutant mice lacking neuropeptide Y or the Y5 receptor. Pharmacology, Biochemistry, and Behavior. 67: 683-91. PMID 11166058 DOI: 10.1016/S0091-3057(00)00413-5  0.305
2000 Ste Marie L, Miura GI, Marsh DJ, Yagaloff K, Palmiter RD. A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 12339-44. PMID 11027312 DOI: 10.1073/pnas.220409497  0.367
2000 Kim DS, Szczypka MS, Palmiter RD. Dopamine-deficient mice are hypersensitive to dopamine receptor agonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4405-13. PMID 10844009 DOI: 10.1523/Jneurosci.20-12-04405.2000  0.605
2000 Jo SM, Won MH, Cole TB, Jensen MS, Palmiter RD, Danscher G. Zinc-enriched (ZEN) terminals in mouse olfactory bulb. Brain Research. 865: 227-36. PMID 10821925 DOI: 10.1016/S0006-8993(00)02227-7  0.443
2000 Lee JY, Cole TB, Palmiter RD, Koh JY. Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC79. PMID 10807937 DOI: 10.1523/Jneurosci.20-11-J0003.2000  0.606
2000 Szczypka MS, Rainey MA, Palmiter RD. Dopamine is required for hyperphagia in Lep(ob/ob) mice. Nature Genetics. 25: 102-4. PMID 10802666 DOI: 10.1038/75484  0.45
2000 Weinshenker D, Rust NC, Miller NS, Palmiter RD. Ethanol-associated behaviors of mice lacking norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3157-64. PMID 10777779 DOI: 10.1523/Jneurosci.20-09-03157.2000  0.552
2000 Cole TB, Robbins CA, Wenzel HJ, Schwartzkroin PA, Palmiter RD. Seizures and neuronal damage in mice lacking vesicular zinc. Epilepsy Research. 39: 153-69. PMID 10759303 DOI: 10.1016/S0920-1211(99)00121-7  0.606
1999 Marsh DJ, Miura GI, Yagaloff KA, Schwartz MW, Barsh GS, Palmiter RD. Effects of neuropeptide Y deficiency on hypothalamic agouti-related protein expression and responsiveness to melanocortin analogues. Brain Research. 848: 66-77. PMID 10612698 DOI: 10.1016/S0006-8993(99)01962-9  0.576
1999 Szot P, Weinshenker D, White SS, Robbins CA, Rust NC, Schwartzkroin PA, Palmiter RD. Norepinephrine-deficient mice have increased susceptibility to seizure-inducing stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10985-92. PMID 10594079 DOI: 10.1523/Jneurosci.19-24-10985.1999  0.582
1999 Marsh DJ, Baraban SC, Hollopeter G, Palmiter RD. Role of the Y5 neuropeptide Y receptor in limbic seizures. Proceedings of the National Academy of Sciences of the United States of America. 96: 13518-23. PMID 10557353 DOI: 10.1073/Pnas.96.23.13518  0.306
1999 Szczypka MS, Rainey MA, Kim DS, Alaynick WA, Marck BT, Matsumoto AM, Palmiter RD. Feeding behavior in dopamine-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 12138-43. PMID 10518589 DOI: 10.1073/Pnas.96.21.12138  0.794
1999 Commins SP, Marsh DJ, Thomas SA, Watson PM, Padgett MA, Palmiter R, Gettys TW. Norepinephrine is required for leptin effects on gene expression in brown and white adipose tissue. Endocrinology. 140: 4772-8. PMID 10499537 DOI: 10.1210/endo.140.10.7043  0.58
1999 Cho MC, Rao M, Koch WJ, Thomas SA, Palmiter RD, Rockman HA. Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine. Circulation. 99: 2702-7. PMID 10338466 DOI: 10.1161/01.Cir.99.20.2702  0.559
1999 Quaife CJ, Cherne RL, Newcomb TG, Kapur RP, Palmiter RD. Metallothionein overexpression suppresses hepatic hyperplasia induced by hepatitis B surface antigen. Toxicology and Applied Pharmacology. 155: 107-16. PMID 10053165 DOI: 10.1006/taap.1998.8609  0.315
1999 Alaniz RC, Thomas SA, Perez-Melgosa M, Mueller K, Farr AG, Palmiter RD, Wilson CB. Dopamine beta-hydroxylase deficiency impairs cellular immunity. Proceedings of the National Academy of Sciences of the United States of America. 96: 2274-8. PMID 10051631 DOI: 10.1073/pnas.96.5.2274  0.561
1999 Szczypka MS, Mandel RJ, Donahue BA, Snyder RO, Leff SE, Palmiter RD. Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice. Neuron. 22: 167-78. PMID 10027299 DOI: 10.1016/S0896-6273(00)80688-1  0.445
1999 Cole TB, Wenzel HJ, Kafer KE, Schwartzkroin PA, Palmiter RD. Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene. Proceedings of the National Academy of Sciences of the United States of America. 96: 1716-21. PMID 9990090 DOI: 10.1073/Pnas.96.4.1716  0.563
1999 Marsh DJ, Hollopeter G, Huszar D, Laufer R, Yagaloff KA, Fisher SL, Burn P, Palmiter RD. Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nature Genetics. 21: 119-22. PMID 9916804 DOI: 10.1038/5070  0.353
1998 Thiele TE, Marsh DJ, Ste Marie L, Bernstein IL, Palmiter RD. Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature. 396: 366-9. PMID 9845072 DOI: 10.1038/24614  0.327
1998 Szczypka MS, Zhou QY, Palmiter RD. Dopamine-stimulated sexual behavior is testosterone dependent in mice. Behavioral Neuroscience. 112: 1229-35. PMID 9829800 DOI: 10.1037//0735-7044.112.5.1229  0.424
1998 Hollopeter G, Erickson JC, Seeley RJ, Marsh DJ, Palmiter RD. Response of neuropeptide Y-deficient mice to feeding effectors. Regulatory Peptides. 75: 383-9. PMID 9802433 DOI: 10.1016/S0167-0115(98)00092-5  0.396
1998 Shi TJ, Zhang X, Berge OG, Erickson JC, Palmiter RD, Hökfelt T. Effect of peripheral axotomy on dorsal root ganglion neuron phenotype and autonomy behaviour in neuropeptide Y-deficient mice. Regulatory Peptides. 75: 161-73. PMID 9802405 DOI: 10.1016/S0167-0115(98)00064-0  0.411
1998 Palmiter RD, Erickson JC, Hollopeter G, Baraban SC, Schwartz MW. Life without neuropeptide Y. Recent Progress in Hormone Research. 53: 163-99. PMID 9769708  0.313
1998 Marsh DJ, Hollopeter G, Kafer KE, Palmiter RD. Role of the Y5 neuropeptide Y receptor in feeding and obesity. Nature Medicine. 4: 718-21. PMID 9623983 DOI: 10.1038/Nm0698-718  0.38
1998 Thomas SA, Marck BT, Palmiter RD, Matsumoto AM. Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. Journal of Neurochemistry. 70: 2468-76. PMID 9603211  0.499
1998 Baskin DG, Seeley RJ, Kuijper JL, Lok S, Weigle DS, Erickson JC, Palmiter RD, Schwartz MW. Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting. Diabetes. 47: 538-43. PMID 9568684 DOI: 10.2337/Diabetes.47.4.538  0.365
1998 Schwartz MW, Erickson JC, Baskin DG, Palmiter RD. Effect of fasting and leptin deficiency on hypothalamic neuropeptide Y gene transcription in vivo revealed by expression of a lacZ reporter gene. Endocrinology. 139: 2629-35. PMID 9564880 DOI: 10.1210/Endo.139.5.6000  0.435
1998 Quaife CJ, Kelly EJ, Masters BA, Brinster RL, Palmiter RD. Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic mice. Toxicology and Applied Pharmacology. 148: 148-57. PMID 9465274 DOI: 10.1006/Taap.1997.8321  0.713
1998 Thomas SA, Palmiter RD. Examining adrenergic roles in development, physiology, and behavior through targeted disruption of the mouse dopamine beta-hydroxylase gene. Advances in Pharmacology (San Diego, Calif.). 42: 57-60. PMID 9327846 DOI: 10.1016/S1054-3589(08)60695-X  0.599
1997 Thomas SA, Palmiter RD. Impaired maternal behavior in mice lacking norepinephrine and epinephrine. Cell. 91: 583-92. PMID 9393852 DOI: 10.1016/S0092-8674(00)80446-8  0.532
1997 Baraban SC, Hollopeter G, Erickson JC, Schwartzkroin PA, Palmiter RD. Knock-out mice reveal a critical antiepileptic role for neuropeptide Y. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8927-36. PMID 9364040 DOI: 10.1523/Jneurosci.17-23-08927.1997  0.352
1997 Wenzel HJ, Cole TB, Born DE, Schwartzkroin PA, Palmiter RD. Ultrastructural localization of zinc transporter-3 (ZnT-3) to synaptic vesicle membranes within mossy fiber boutons in the hippocampus of mouse and monkey. Proceedings of the National Academy of Sciences of the United States of America. 94: 12676-81. PMID 9356509 DOI: 10.1073/Pnas.94.23.12676  0.536
1997 Kelly EJ, Sandgren EP, Brinster RL, Palmiter RD. A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proceedings of the National Academy of Sciences of the United States of America. 94: 10045-50. PMID 9294160 DOI: 10.1073/Pnas.94.19.10045  0.684
1997 Erickson JC, Ahima RS, Hollopeter G, Flier JS, Palmiter RD. Endocrine function of neuropeptide Y knockout mice. Regulatory Peptides. 70: 199-202. PMID 9272634 DOI: 10.1016/S0167-0115(97)01007-0  0.378
1997 Thomas SA, Palmiter RD. Disruption of the dopamine beta-hydroxylase gene in mice suggests roles for norepinephrine in motor function, learning, and memory. Behavioral Neuroscience. 111: 579-89. PMID 9189272 DOI: 10.1037/0735-7044.111.3.579  0.572
1997 Tafari AT, Thomas SA, Palmiter RD. Norepinephrine facilitates the development of the murine sweat response but is not essential. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4275-81. PMID 9151744 DOI: 10.1523/Jneurosci.17-11-04275.1997  0.591
1997 Thomas SA, Palmiter RD. Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline. Nature. 387: 94-7. PMID 9139828 DOI: 10.1038/387094a0  0.529
1997 Erickson JC, Hollopeter G, Thomas SA, Froelick GJ, Palmiter RD. Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1271-81. PMID 9006971 DOI: 10.1523/Jneurosci.17-04-01271.1997  0.583
1996 Palmiter RD, Cole TB, Quaife CJ, Findley SD. ZnT-3, a putative transporter of zinc into synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 93: 14934-9. PMID 8962159 DOI: 10.1073/pnas.93.25.14934  0.492
1996 Dalton T, Fu K, Enders GC, Palmiter RD, Andrews GK. Analysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmium. Environmental Health Perspectives. 104: 68-76. PMID 8834864 DOI: 10.1289/Ehp.9610468  0.356
1996 Quaife CJ, Veith GC, Palmiter RD. Transformation of liver by SV-40 T-antigen in transgenic mice is unaffected by metallothionein. Cancer Letters. 106: 125-31. PMID 8827056 DOI: 10.1016/0304-3835(96)04316-9  0.337
1996 Kelly EJ, Quaife CJ, Froelick GJ, Palmiter RD. Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice. The Journal of Nutrition. 126: 1782-90. PMID 8683339 DOI: 10.1093/Jn/126.7.1782  0.612
1996 Liu YP, Liu J, Palmiter RD, Klaassen CD. Metallothionein-I-transgenic mice are not protected from acute cadmium-metallothionein-induced nephrotoxicity. Toxicology and Applied Pharmacology. 137: 307-15. PMID 8661357 DOI: 10.1006/Taap.1996.0085  0.35
1996 Kelly EJ, Palmiter RD. A murine model of Menkes disease reveals a physiological function of metallothionein. Nature Genetics. 13: 219-22. PMID 8640230 DOI: 10.1038/Ng0696-219  0.568
1996 Erickson JC, Clegg KE, Palmiter RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature. 381: 415-21. PMID 8632796 DOI: 10.1038/381415a0  0.358
1996 Kapur RP, Livingston R, Doggett B, Sweetser DA, Siebert JR, Palmiter RD. Abnormal microenvironmental signals underlie intestinal aganglionosis in Dominant megacolon mutant mice. Developmental Biology. 174: 360-9. PMID 8631507 DOI: 10.1006/Dbio.1996.0080  0.32
1996 Verchere CB, D'Alessio DA, Palmiter RD, Weir GC, Bonner-Weir S, Baskin DG, Kahn SE. Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. Proceedings of the National Academy of Sciences of the United States of America. 93: 3492-6. PMID 8622964 DOI: 10.1073/Pnas.93.8.3492  0.331
1996 Palmiter RD, Cole TB, Findley SD. ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. The Embo Journal. 15: 1784-91. PMID 8617223 DOI: 10.1002/J.1460-2075.1996.Tb00527.X  0.509
1996 Dalton T, Fu K, Palmiter RD, Andrews GK. Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency. The Journal of Nutrition. 126: 825-33. PMID 8613884 DOI: 10.1093/Jn/126.4.825  0.375
1995 Zhou QY, Palmiter RD. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell. 83: 1197-209. PMID 8548806 DOI: 10.1016/0092-8674(95)90145-0  0.469
1995 Wu ZL, Thomas SA, Villacres EC, Xia Z, Simmons ML, Chavkin C, Palmiter RD, Storm DR. Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 220-4. PMID 7816821 DOI: 10.1073/Pnas.92.1.220  0.513
1995 Rhim JA, Sandgren EP, Palmiter RD, Brinster RL. Complete reconstitution of mouse liver with xenogeneic hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 4942-6. PMID 7761429 DOI: 10.1073/PNAS.92.11.4942  0.527
1995 Thomas SA, Matsumoto AM, Palmiter RD. Noradrenaline is essential for mouse fetal development. Nature. 374: 643-6. PMID 7715704 DOI: 10.1038/374643a0  0.537
1995 Zhou QY, Quaife CJ, Palmiter RD. Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature. 374: 640-3. PMID 7715703 DOI: 10.1038/374640a0  0.376
1995 Rhim JA, Connor W, Dixon GH, Harendza CJ, Evenson DP, Palmiter RD, Brinster RL. Expression of an avian protamine in transgenic mice disrupts chromatin structure in spermatozoa. Biology of Reproduction. 52: 20-32. PMID 7711180 DOI: 10.1095/Biolreprod52.1.20  0.535
1995 Erickson JC, Masters BA, Kelly EJ, Brinster RL, Palmiter RD. Expression of human metallothionein-III in transgenic mice. Neurochemistry International. 27: 35-41. PMID 7655346 DOI: 10.1016/0197-0186(94)00166-R  0.693
1994 Masters BA, Kelly EJ, Quaife CJ, Brinster RL, Palmiter RD. Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proceedings of the National Academy of Sciences of the United States of America. 91: 584-8. PMID 8290567 DOI: 10.1073/Pnas.91.2.584  0.693
1994 Hoyle GW, Mercer EH, Palmiter RD, Brinster RL. Cell-specific expression from the human dopamine beta-hydroxylase promoter in transgenic mice is controlled via a combination of positive and negative regulatory elements. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2455-63. PMID 8182421  0.347
1994 Winn SR, Hammang JP, Emerich DF, Lee A, Palmiter RD, Baetge EE. Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 2324-8. PMID 8134395 DOI: 10.1073/Pnas.91.6.2324  0.301
1994 Rhim JA, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. Replacement of diseased mouse liver by hepatic cell transplantation. Science (New York, N.Y.). 263: 1149-52. PMID 8108734 DOI: 10.1126/Science.8108734  0.478
1994 Quaife CJ, Findley SD, Erickson JC, Froelick GJ, Kelly EJ, Zambrowicz BP, Palmiter RD. Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry. 33: 7250-9. PMID 8003488 DOI: 10.1021/Bi00189A029  0.567
1994 Quaife CJ, Hoyle GW, Froelick GJ, Findley SD, Baetge EE, Behringer RR, Hammang JP, Brinster RL, Palmiter RD. Visualization and ablation of phenylethanolamine N-methyltransferase producing cells in transgenic mice. Transgenic Research. 3: 388-400. PMID 8000434 DOI: 10.1007/Bf01976770  0.66
1994 Bamber BA, Masters BA, Hoyle GW, Brinster RL, Palmiter RD. Leukemia inhibitory factor induces neurotransmitter switching in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 7839-43. PMID 7914698 DOI: 10.1073/pnas.91.17.7839  0.596
1994 Masters B, Quaife C, Erickson J, Kelly E, Froelick G, Zambrowicz B, Brinster R, Palmiter R. Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles The Journal of Neuroscience. 14: 5844-5857. DOI: 10.1523/Jneurosci.14-10-05844.1994  0.69
1994 Messing A, Behringer R, Wrabetz L, Hammang J, Lemke G, Palmiter R, Brinster R. Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen The Journal of Neuroscience. 14: 3533-3539. DOI: 10.1523/Jneurosci.14-06-03533.1994  0.661
1994 Hoyle G, Mercer E, Palmiter R, Brinster R. Cell-specific expression from the human dopamine beta-hydroxylase promoter in transgenic mice is controlled via a combination of positive and negative regulatory elements The Journal of Neuroscience. 14: 2455-2463. DOI: 10.1523/JNEUROSCI.14-05-02455.1994  0.529
1993 Le Van Thai A, Coste E, Allen JM, Palmiter RD, Weber MJ. Identification of a neuron-specific promoter of human aromatic L-amino acid decarboxylase gene. Brain Research. Molecular Brain Research. 17: 227-38. PMID 8510497 DOI: 10.1016/0169-328X(93)90006-B  0.339
1993 Sandgren EP, Luetteke NC, Qiu TH, Palmiter RD, Brinster RL, Lee DC. Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver. Molecular and Cellular Biology. 13: 320-30. PMID 8417334 DOI: 10.1128/MCB.13.1.320  0.43
1993 Hammang JP, Behringer RR, Baetge EE, Palmiter RD, Brinster RL, Messing A. Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration. Neuron. 10: 1197-209. PMID 8391281 DOI: 10.1016/0896-6273(93)90067-2  0.559
1993 Zambrowicz BP, Harendza CJ, Zimmermann JW, Brinster RL, Palmiter RD. Analysis of the mouse protamine 1 promoter in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 5071-5. PMID 8389466 DOI: 10.1073/Pnas.90.11.5071  0.566
1993 Palmiter RD, Sandgren EP, Koeller DM, Brinster RL. Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Molecular and Cellular Biology. 13: 5266-75. PMID 8355681 DOI: 10.1128/MCB.13.9.5266  0.513
1993 Kapur RP, Yost C, Palmiter RD. Aggregation chimeras demonstrate that the primary defect responsible for aganglionic megacolon in lethal spotted mice is not neuroblast autonomous. Development (Cambridge, England). 117: 993-9. PMID 8325247  0.331
1993 Hoyle GW, Mercer EH, Palmiter RD, Brinster RL. Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues. Neuron. 10: 1019-34. PMID 8318227 DOI: 10.1016/0896-6273(93)90051-R  0.537
1992 Palmiter RD, Findley SD, Whitmore TE, Durnam DM. MT-III, a brain-specific member of the metallothionein gene family. Proceedings of the National Academy of Sciences of the United States of America. 89: 6333-7. PMID 1631128 DOI: 10.1073/Pnas.89.14.6333  0.308
1992 Kapur RP, Yost C, Palmiter RD. A transgenic model for studying development of the enteric nervous system in normal and aganglionic mice. Development (Cambridge, England). 116: 167-75. PMID 1483385  0.337
1992 Cadd GG, Hoyle GW, Quaife CJ, Marck B, Matsumoto AM, Brinster RL, Palmiter RD. Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 6: 1951-60. PMID 1480181 DOI: 10.1210/Mend.6.11.1480181  0.653
1992 Sandgren EP, Palmiter RD, Heckel JL, Brinster RL, Degen JL. DNA rearrangement causes hepatocarcinogenesis in albumin-plasminogen activator transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 89: 11523-7. PMID 1454842 DOI: 10.1073/Pnas.89.23.11523  0.554
1992 Messing A, Behringer RR, Hammang JP, Palmiter RD, Brinster RL, Lemke G. P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice. Neuron. 8: 507-20. PMID 1372510 DOI: 10.1016/0896-6273(92)90279-M  0.536
1992 Lo D, Freedman J, Hesse S, Palmiter RD, Brinster RL, Sherman LA. Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells. European Journal of Immunology. 22: 1013-22. PMID 1348026 DOI: 10.1002/eji.1830220421  0.471
1992 Peschon JJ, Behringer RR, Cate RL, Harwood KA, Idzerda RL, Brinster RL, Palmiter RD. Directed expression of an oncogene to Sertoli cells in transgenic mice using mullerian inhibiting substance regulatory sequences. Molecular Endocrinology (Baltimore, Md.). 6: 1403-11. PMID 1331774 DOI: 10.1210/Mend.6.9.1331774  0.643
1991 Maronpot RR, Palmiter RD, Brinster RL, Sandgren EP. Pulmonary carcinogenesis in transgenic mice. Experimental Lung Research. 17: 305-20. PMID 2050033 DOI: 10.3109/01902149109064420  0.525
1991 Lo D, Pursel V, Linton PJ, Sandgren E, Behringer R, Rexroad C, Palmiter RD, Brinster RL. Expression of mouse IgA by transgenic mice, pigs and sheep. European Journal of Immunology. 21: 1001-6. PMID 2019284 DOI: 10.1002/Eji.1830210421  0.66
1991 Caterina JJ, Ryan TM, Pawlik KM, Palmiter RD, Brinster RL, Behringer RR, Townes TM. Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 88: 1626-30. PMID 2000371 DOI: 10.1073/Pnas.88.5.1626  0.607
1991 Palmiter RD, Sandgren EP, Avarbock MR, Allen DD, Brinster RL. Heterologous introns can enhance expression of transgenes in mice. Proceedings of the National Academy of Sciences of the United States of America. 88: 478-82. PMID 1988947 DOI: 10.1073/PNAS.88.2.478  0.503
1991 Sandgren EP, Quaife CJ, Paulovich AG, Palmiter RD, Brinster RL. Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proceedings of the National Academy of Sciences of the United States of America. 88: 93-7. PMID 1986386 DOI: 10.1073/PNAS.88.1.93  0.522
1991 Guthrie HD, Pursel VG, Miller KF, Bolt DJ, Palmiter RD, Brinster RL. Effect of bovine growth hormone gene expression, sex and age on plasma gonadotropins, estrone and testosterone in prepuberal pigs. Domestic Animal Endocrinology. 8: 423-9. PMID 1748001 DOI: 10.1016/0739-7240(91)90010-H  0.514
1991 Kapur RP, Hoyle GW, Mercer EH, Brinster RL, Palmiter RD. Some neuronal cell populations express human dopamine beta-hydroxylase-lacZ transgenes transiently during embryonic development. Neuron. 7: 717-27. PMID 1742022 DOI: 10.1016/0896-6273(91)90275-5  0.574
1991 Mercer EH, Hoyle GW, Kapur RP, Brinster RL, Palmiter RD. The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron. 7: 703-16. PMID 1742021 DOI: 10.1016/0896-6273(91)90274-4  0.59
1991 Rexroad CE, Mayo K, Bolt DJ, Elsasser TH, Miller KF, Behringer RR, Palmiter RD, Brinster RL. Transferrin- and albumin-directed expression of growth-related peptides in transgenic sheep. Journal of Animal Science. 69: 2995-3004. PMID 1715850 DOI: 10.2527/1991.6972995X  0.485
1991 Sandgren EP, Palmiter RD, Heckel JL, Daugherty CC, Brinster RL, Degen JL. Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell. 66: 245-56. PMID 1713128 DOI: 10.1016/0092-8674(91)90615-6  0.335
1991 Wilkie TM, Braun RE, Ehrman WJ, Palmiter RD, Hammer RE. Germ-line intrachromosomal recombination restores fertility in transgenic MyK-103 male mice. Genes & Development. 5: 38-48. PMID 1671218 DOI: 10.1101/Gad.5.1.38  0.613
1990 Behringer RR, Lewin TM, Quaife CJ, Palmiter RD, Brinster RL, D'Ercole AJ. Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice. Endocrinology. 127: 1033-40. PMID 2387246 DOI: 10.1210/Endo-127-3-1033  0.642
1990 Hammang JP, Baetge EE, Behringer RR, Brinster RL, Palmiter RD, Messing A. Immortalized retinal neurons derived from SV40 T-antigen-induced tumors in transgenic mice. Neuron. 4: 775-82. PMID 2344410 DOI: 10.1016/0896-6273(90)90204-S  0.676
1990 Behringer RR, Cate RL, Froelick GJ, Palmiter RD, Brinster RL. Abnormal sexual development in transgenic mice chronically expressing müllerian inhibiting substance. Nature. 345: 167-70. PMID 2336108 DOI: 10.1038/345167A0  0.509
1990 Lo D, Burkly LC, Flavell RA, Palmiter RD, Brinster RL. Antigen presentation in MHC class II transgenic mice: stimulation versus tolerization. Immunological Reviews. 117: 121-34. PMID 2258189 DOI: 10.1111/J.1600-065X.1990.Tb00570.X  0.53
1990 Ryan TM, Townes TM, Reilly MP, Asakura T, Palmiter RD, Brinster RL, Behringer RR. Human sickle hemoglobin in transgenic mice. Science (New York, N.Y.). 247: 566-8. PMID 2154033 DOI: 10.1126/Science.2154033  0.653
1990 Braun RE, Lo D, Pinkert CA, Widera G, Flavell RA, Palmiter RD, Brinster RL. Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells. Biology of Reproduction. 43: 684-93. PMID 1963095 DOI: 10.1095/Biolreprod43.4.684  0.715
1990 Heckel JL, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell. 62: 447-56. PMID 1696178 DOI: 10.1016/0092-8674(90)90010-C  0.586
1990 Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell. 61: 1121-35. PMID 1693546 DOI: 10.1016/0092-8674(90)90075-P  0.457
1990 Behringer RR, Ryan TM, Palmiter RD, Brinster RL, Townes TM. Human gamma- to beta-globin gene switching in transgenic mice. Genes & Development. 4: 380-9. PMID 1692558 DOI: 10.1101/Gad.4.3.380  0.627
1990 Moriyama T, Guilhot S, Klopchin K, Moss B, Pinkert CA, Palmiter RD, Brinster RL, Kanagawa O, Chisari FV. Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science (New York, N.Y.). 248: 361-4. PMID 1691527 DOI: 10.1126/Science.1691527  0.445
1990 BEHRINGER RR, RYAN TM, REILLY MP, ASAKURA T, PALMITER RD, BRINSTER RL, TOWNES TM. A Transgenic Mouse Model for Human Sickle Cell Disease Proceedings of the Japanese Association of Animal Models For Human Diseases. 6: 6-12. DOI: 10.1538/Expanim1985.6.6  0.562
1989 Markmann J, Lo D, Naji A, Palmiter RD, Brinster RL, Heber-Katz E. Antigen presenting function of class II MHC expressing pancreatic beta cells. Nature. 336: 476-9. PMID 3143077 DOI: 10.1038/336476A0  0.496
1989 Miller KF, Bolt DJ, Pursel VG, Hammer RE, Pinkert CA, Palmiter RD, Brinster RL. Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I Journal of Endocrinology. 120: 481-488. PMID 2926315 DOI: 10.1677/Joe.0.1200481  0.483
1989 Ryan TM, Behringer RR, Townes TM, Palmiter RD, Brinster RL. High-level erythroid expression of human α-globin genes in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 86: 37-41. PMID 2911581 DOI: 10.1073/Pnas.86.1.37  0.596
1989 Braun RE, Behringer RR, Peschon JJ, Brinster RL, Palmiter RD. Genetically haploid spermatids are phenotypically diploid. Nature. 337: 373-6. PMID 2911388 DOI: 10.1038/337373A0  0.71
1989 Habener JF, Cwikel BJ, Hermann H, Hammer RE, Palmiter RD, Brinster RL. Metallothionein-vasopressin fusion gene expression in transgenic mice. Nephrogenic diabetes insipidus and brain transcripts localized to magnocellular neurons. The Journal of Biological Chemistry. 264: 18844-52. PMID 2808395  0.327
1989 Brinster RL, Sandgren EP, Behringer RR, Palmiter RD. No simple solution for making transgenic mice. Cell. 59: 239-41. PMID 2805065 DOI: 10.1016/0092-8674(89)90282-1  0.617
1989 Peschon JJ, Behringer RR, Palmiter RD, Brinster RL. Expression of mouse protamine 1 genes in transgenic mice. Annals of the New York Academy of Sciences. 564: 186-97. PMID 2774416 DOI: 10.1111/J.1749-6632.1989.Tb25897.X  0.656
1989 Behringer RR, Ryan TM, Reilly MP, Asakura T, Palmiter RD, Brinster RL, Townes TM. Synthesis of functional human hemoglobin in transgenic mice. Science (New York, N.Y.). 245: 971-3. PMID 2772649 DOI: 10.1126/Science.2772649  0.641
1989 Braun RE, Peschon JJ, Behringer RR, Brinster RL, Palmiter RD. Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes & Development. 3: 793-802. PMID 2744463 DOI: 10.1101/Gad.3.6.793  0.74
1989 Ryan TM, Behringer RR, Martin NC, Townes TM, Palmiter RD, Brinster RL. A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice Genes &Amp; Development. 3: 314-323. PMID 2721958 DOI: 10.1101/gad.3.3.314  0.578
1989 Quaife CJ, Mathews LS, Pinkert CA, Hammer RE, Brinster RL, Palmiter RD. Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. Endocrinology. 124: 40-8. PMID 2642417 DOI: 10.1210/Endo-124-1-40  0.531
1989 Wolgemuth DJ, Behringer RR, Mostoller MP, Brinster RL, Palmiter RD. Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development. Nature. 337: 464-7. PMID 2563568 DOI: 10.1038/337464A0  0.659
1989 Lo D, Burkly LC, Flavell RA, Palmiter RD, Brinster RL. Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells. The Journal of Experimental Medicine. 170: 87-104. PMID 2526197 DOI: 10.1084/Jem.170.1.87  0.508
1989 Brinster RL, Braun RE, Lo D, Avarbock MR, Oram F, Palmiter RD. Targeted correction of a major histocompatibility class II E alpha gene by DNA microinjected into mouse eggs. Proceedings of the National Academy of Sciences of the United States of America. 86: 7087-91. PMID 2506546 DOI: 10.1073/Pnas.86.18.7087  0.666
1989 Pursel VG, Pinkert CA, Miller KF, Bolt DJ, Campbell RG, Palmiter RD, Brinster RL, Hammer RE. Genetic engineering of livestock. Science (New York, N.Y.). 244: 1281-8. PMID 2499927 DOI: 10.1126/Science.2499927  0.462
1989 Messing A, Behrinqer RR, Hammang JP, Lemke G, Brinster RL, Palmiter RD. SCHWANN-CEIL-SPECIFIC GENE EXPRESSION IN TRANSGENIC MICE Journal of Neuropathology and Experimental Neurology. 48: 347. DOI: 10.1097/00005072-198905000-00144  0.544
1988 Brinster RL, Allen JM, Behringer RR, Gelinas RE, Palmiter RD. Introns increase transcriptional efficiency in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 85: 836-40. PMID 3422466 DOI: 10.1073/Pnas.85.3.836  0.612
1988 Mathews LS, Hammer RE, Brinster RL, Palmiter RD. Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. Endocrinology. 123: 433-7. PMID 3383777 DOI: 10.1210/endo-123-1-433  0.544
1988 Behringer RR, Mathews LS, Palmiter RD, Brinster RL. Dwarf mice produced by genetic ablation of growth hormone-expressing cells. Genes & Development. 2: 453-61. PMID 3286373 DOI: 10.1101/Gad.2.4.453  0.641
1988 Marrack P, Lo D, Brinster R, Palmiter R, Burkly L, Flavell RH, Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 53: 627-34. PMID 3259471 DOI: 10.1016/0092-8674(88)90578-8  0.427
1988 Mathews LS, Hammer RE, Behringer RR, D'Ercole AJ, Bell GI, Brinster RL, Palmiter RD. Growth enhancement of transgenic mice expressing human insulin-like growth factor I. Endocrinology. 123: 2827-33. PMID 3197646 DOI: 10.1210/endo-123-6-2827  0.632
1988 Lo D, Burkly LC, Widera G, Cowing C, Flavell RA, Palmiter RD, Brinster RL. Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell. 53: 159-68. PMID 2964908 DOI: 10.1016/0092-8674(88)90497-7  0.524
1988 Baetge EE, Behringer RR, Messing A, Brinster RL, Palmiter RD. Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina. Proceedings of the National Academy of Sciences of the United States of America. 85: 3648-52. PMID 2835776 DOI: 10.1073/Pnas.85.10.3648  0.644
1988 Behringer RR, Peschon JJ, Messing A, Gartside CL, Hauschka SD, Palmiter RD, Brinster RL. Heart and bone tumors in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 85: 2648-52. PMID 2833748 DOI: 10.1073/Pnas.85.8.2648  0.592
1987 Quaife C, Hammer RE, Mottet NK, Palmiter RD. Glucocorticoid regulation of metallothionein during murine development. Developmental Biology. 118: 549-55. PMID 3792622 DOI: 10.1016/0012-1606(86)90025-4  0.32
1987 Ornitz DM, Hammer RE, Davison BL, Brinster RL, Palmiter RD. Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers Molecular and Cellular Biology. 7: 3466-3472. PMID 3683390 DOI: 10.1128/Mcb.7.10.3466  0.551
1987 Pinkert CA, Ornitz DM, Brinster RL, Palmiter RD. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice Genes &Amp; Development. 1: 268-276. PMID 3678824 DOI: 10.1101/Gad.1.3.268  0.556
1987 Hammer RE, Swift GH, Ornitz DM, Quaife CJ, Palmiter RD, Brinster RL, MacDonald RJ. The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice Molecular and Cellular Biology. 7: 2956-2967. PMID 3670302 DOI: 10.1128/Mcb.7.8.2956  0.5
1987 Palmiter RD, Behringer RR, Quaife CJ, Maxwell F, Maxwell IH, Brinster RL. Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell. 50: 435-43. PMID 3649277 DOI: 10.1016/0092-8674(87)90497-1  0.66
1987 Wilkie TM, Palmiter RD. Analysis of the integrant in MyK-103 transgenic mice in which males fail to transmit the integrant. Molecular and Cellular Biology. 7: 1646-55. PMID 3600641 DOI: 10.1128/MCB.7.5.1646  0.302
1987 Palmiter RD, Brinster RL. Germ-line transformation of mice. Annual Review of Genetics. 20: 465-99. PMID 3545063 DOI: 10.1146/annurev.ge.20.120186.002341  0.54
1987 Cory S, Harris AW, Langdon WY, Alexander WS, Corcoran LM, Palmiter RD, Pinkert CA, Brinster RL, Adams JM. The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice. Haematology and Blood Transfusion. 31: 248-51. PMID 3502109 DOI: 10.1007/978-3-642-72624-8_51  0.528
1987 Widera G, Burkly LC, Pinkert CA, Böttger EC, Cowing C, Palmiter RD, Brinster RL, Flavell RA. Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: an in vivo approach to investigate Ia gene function. Cell. 51: 175-87. PMID 3499228 DOI: 10.1016/0092-8674(87)90145-0  0.334
1987 Pursel VG, Rexroad CE, Bolt DJ, Miller KF, Wall RJ, Hammer RE, Pinkert CA, Palmiter RD, Brinster RL. Progress on gene transfer in farm animals Veterinary Immunology and Immunopathology. 17: 303-312. PMID 3481144 DOI: 10.1016/0165-2427(87)90149-8  0.539
1987 Behringer RR, Hammer RE, Brinster RL, Palmiter RD, Townes TM. Two 3' sequences direct adult erythroid-specific expression of human β-globulin genes in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 84: 7056-7060. PMID 3478680 DOI: 10.1073/Pnas.84.20.7056  0.583
1987 Chisari FV, Filippi P, Buras J, McLachlan A, Popper H, Pinkert CA, Palmiter RD, Brinster RL. Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 84: 6909-13. PMID 3477814 DOI: 10.1073/Pnas.84.19.6909  0.453
1987 Quaife CJ, Pinkert CA, Ornitz DM, Palmiter RD, Brinster RL. Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice Cell. 48: 1023-1034. PMID 3470144 DOI: 10.1016/0092-8674(87)90710-0  0.543
1987 MacDonald RJ, Swift GH, Hammer RE, Ornitz DM, Davis BP, Brinster RL, Palmiter RD. Chapter 1 Targeted expression of cloned genes in transgenic mice Progress in Brain Research. 71: 3-12. PMID 3295992 DOI: 10.1016/S0079-6123(08)61809-9  0.55
1987 Palmiter RD, Brinster RL. Gene transplants into germ cells. Hospital Practice (Office Ed.). 22: 77-83, 87-8. PMID 3040788 DOI: 10.1080/21548331.1987.11703306  0.478
1987 Peschon JJ, Behringer RR, Brinster RL, Palmiter RD. Spermatid-specific expression of protamine 1 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 84: 5316-9. PMID 3037541 DOI: 10.1073/pnas.84.15.5316  0.639
1987 Palmiter RD. Molecular biology of metallothionein gene expression. Experientia. Supplementum. 52: 63-80. PMID 2959555 DOI: 10.1007/978-3-0348-6784-9_4  0.308
1987 Ornitz DM, Hammer RE, Messing A, Palmiter RD, Brinster RL. Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. Science (New York, N.Y.). 238: 188-93. PMID 2821617 DOI: 10.1126/Science.2821617  0.526
1987 Pinkert CA, Brinster RL, Palmiter RD, Wong C, Butel JS. Tumorigenesis in transgenic mice by a nuclear transport-defective SV40 large T-antigen gene. Virology. 160: 169-75. PMID 2820126 DOI: 10.1016/0042-6822(87)90057-2  0.477
1987 Messing A, Pinkert CA, Palmiter RD, Brinster RL. DEVELOPMENTAL STUDY OF SV*** GENE EXPRESSION IN TRANSGENIC MICE WITH DISORDERS OF CHOROID PLEXUS, THYMUS AND KIDNEY Journal of Neuropathology and Experimental Neurology. 46: 373. DOI: 10.1097/00005072-198705000-00132  0.517
1986 Chisari FV, Filippi P, McLachlan A, Milich DR, Riggs M, Lee S, Palmiter RD, Pinkert CA, Brinster RL. Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. Journal of Virology. 60: 880-7. PMID 3783819 DOI: 10.1128/Jvi.60.3.880-887.1986  0.438
1986 Wilkie TM, Brinster RL, Palmiter RD. Germline and somatic mosaicism in transgenic mice. Developmental Biology. 118: 9-18. PMID 3770310 DOI: 10.1016/0012-1606(86)90068-0  0.548
1986 MacDonald RJ, Hammer RE, Swift GH, Ornitz DM, Davis BP, Palmiter RD, Brinster RL. Tissue-specific expression of pancreatic genes in transgenic mice Annals of the New York Academy of Sciences. 478: 131-146. PMID 3541749 DOI: 10.1111/J.1749-6632.1986.Tb15527.X  0.576
1986 Adams JM, Harris AW, Langdon WY, Pinkert CA, Brinster RL, Palmiter RD, Corcoran L, Alexander WS, Graham MW, Cory S. c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia. Current Topics in Microbiology and Immunology. 132: 1-8. PMID 3491731 DOI: 10.1007/978-3-642-71562-4_1  0.504
1986 Hammer RE, Pursel VG, Rexroad CE, Wall RJ, Bolt DJ, Palmiter RD, Brinster RL. Genetic engineering of mammalian embryos. Journal of Animal Science. 63: 269-78. PMID 3460980 DOI: 10.2527/jas1986.631269x  0.466
1986 Hammer RE, Brinster RL, Palmiter RD. Use of gene transfer to increase animal growth. Cold Spring Harbor Symposia On Quantitative Biology. 50: 379-87. PMID 3006997 DOI: 10.1101/SQB.1985.050.01.048  0.422
1985 Palmiter RD, Hammer RE, Brinster RL. Expression of Growth Hormone Genes in Transgenic Mice. Banbury Report. 20: 123-132. PMID 27358506  0.541
1985 Brinster RL, Palmiter RD. Transgenic mice containing growth hormone fusion genes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 309-12. PMID 6151702 DOI: 10.1098/rstb.1984.0132  0.589
1985 Adams JM, Harris AW, Pinkert CA, Corcoran LM, Alexander WS, Cory S, Palmiter RD, Brinster RL. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature. 318: 533-8. PMID 3906410 DOI: 10.1038/318533A0  0.557
1985 Brinster RL, Chen HY, Trumbauer ME, Yagle MK, Palmiter RD. Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proceedings of the National Academy of Sciences of the United States of America. 82: 4438-42. PMID 3892534 DOI: 10.1073/pnas.82.13.4438  0.562
1985 Hammer RE, Pursel VG, Rexroad CE, Wall RJ, Bolt DJ, Ebert KM, Palmiter RD, Brinster RL. Production of transgenic rabbits, sheep and pigs by microinjection. Nature. 315: 680-3. PMID 3892305 DOI: 10.1038/315680a0  0.579
1985 Chisari FV, Pinkert CA, Milich DR, Filippi P, McLachlan A, Palmiter RD, Brinster RL. A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science (New York, N.Y.). 230: 1157-60. PMID 3865369 DOI: 10.1126/Science.3865369  0.464
1985 Ornitz DM, Palmiter RD, Hammer RE, Brinster RL, Swift GH, MacDonald RJ. Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice Nature. 313: 600-602. PMID 3844051 DOI: 10.1038/313600A0  0.562
1985 Townes TM, Chen HY, Lingrel JB, Palmiter RD, Brinster RL. Expression of human β-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene Molecular and Cellular Biology. 5: 1977-1983. PMID 3018541 DOI: 10.1128/Mcb.5.8.1977  0.548
1985 Ornitz DM, Palmiter RD, Messing A, Hammer RE, Pinkert CA, Brinster RL. Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. Cold Spring Harbor Symposia On Quantitative Biology. 50: 399-409. PMID 3006998 DOI: 10.1101/Sqb.1985.050.01.050  0.567
1985 Messing A, Chen HY, Palmiter RD, Brinster RL. Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice. Nature. 316: 461-3. PMID 2991772 DOI: 10.1038/316461A0  0.583
1985 Palmiter RD, Chen HY, Messing A, Brinster RL. SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature. 316: 457-60. PMID 2991771 DOI: 10.1038/316457A0  0.552
1985 Palmiter RD, Brinster RL. Transgenic mice. Cell. 41: 343-5. PMID 2985274 DOI: 10.1016/S0092-8674(85)80004-0  0.527
1985 Low MJ, Hammer RE, Goodman RH, Habener JF, Palmiter RD, Brinster RL. Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice. Cell. 41: 211-9. PMID 2859927 DOI: 10.1016/0092-8674(85)90075-3  0.543
1985 Mayo KE, Palmiter RD. CHAPTER 3 – Glucocorticoid Regulation of Metallothionein Gene Expression Biochemical Actions of Hormones. 69-88. DOI: 10.1016/B978-0-12-452812-3.50007-5  0.593
1985 Pinkert C, Widera G, Cowing C, Heber-Katz E, Palmiter R, Flavell R, Brinster R. Tissue-specific, inducible and functional expression of the E alpha d MHC class II gene in transgenic mice. The Embo Journal. 4: 2225-2230. DOI: 10.1002/J.1460-2075.1985.Tb03918.X  0.559
1985 Townes T, Lingrel J, Chen H, Brinster R, Palmiter R. Erythroid-specific expression of human beta-globin genes in transgenic mice. The Embo Journal. 4: 1715-1723. DOI: 10.1002/J.1460-2075.1985.Tb03841.X  0.552
1984 Hammer RE, Palmiter RD, Brinster RL. Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene. Nature. 311: 65-7. PMID 6472463 DOI: 10.1038/311065a0  0.542
1984 Brinster RL, Chen HY, Messing A, van Dyke T, Levine AJ, Palmiter RD. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell. 37: 367-79. PMID 6327063 DOI: 10.1016/0092-8674(84)90367-2  0.558
1984 Palmiter RD, Wilkie TM, Chen HY, Brinster RL. Transmission distortion and mosaicism in an unusual transgenic mouse pedigree. Cell. 36: 869-77. PMID 6323025 DOI: 10.1016/0092-8674(84)90036-9  0.53
1984 Norstedt G, Palmiter R. Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver. Cell. 36: 805-12. PMID 6323022 DOI: 10.1016/0092-8674(84)90030-8  0.348
1984 Durnam DM, Hoffman JS, Quaife CJ, Benditt EP, Chen HY, Brinster RL, Palmiter RD. Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones. Proceedings of the National Academy of Sciences of the United States of America. 81: 1053-6. PMID 6322185 DOI: 10.1073/Pnas.81.4.1053  0.509
1984 Stuart GW, Searle PF, Chen HY, Brinster RL, Palmiter RD. A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene Proceedings of the National Academy of Sciences of the United States of America. 81: 7318-7322. PMID 6095286 DOI: 10.1073/pnas.81.23.7318  0.512
1983 Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM. Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature. 300: 611-5. PMID 6958982 DOI: 10.1038/300611a0  0.557
1983 Palmiter RD, Norstedt G, Gelinas RE, Hammer RE, Brinster RL. Metallothionein-human GH fusion genes stimulate growth of mice. Science (New York, N.Y.). 222: 809-14. PMID 6356363 DOI: 10.1126/science.6356363  0.512
1982 Palmiter RD, Chen HY, Brinster RL. Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring. Cell. 29: 701-10. PMID 7116454 DOI: 10.1016/0092-8674(82)90186-6  0.582
1982 Mayo KE, Warren R, Palmiter RD. The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells Cell. 29: 99-108. PMID 6955027 DOI: 10.1016/0092-8674(82)90094-0  0.597
1982 Brinster RL, Chen HY, Warren R, Sarthy A, Palmiter RD. Regulation of metallothionein--thymidine kinase fusion plasmids injected into mouse eggs. Nature. 296: 39-42. PMID 6278311 DOI: 10.1038/296039a0  0.521
1982 Brinster RL, Chen HY, Trumbauer M, Senear AW, Warren R, Palmiter RD. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell. 27: 223-31. PMID 6276022 DOI: 10.1016/0092-8674(81)90376-7  0.572
1982 Brinster R, Palmiter R. Induction of foreign genes in animals Trends in Biochemical Sciences. 7: 438-440. DOI: 10.1016/S0968-0004(82)80012-1  0.441
1981 Lemeur M, Glanville N, Mandel JL, Gerlinger P, Palmiter R, Chambon P. The ovalbumin gene family: Hormonal control of X and Y gene transcription and mRNA accumulation Cell. 23: 561-571. PMID 7471213 DOI: 10.1016/0092-8674(81)90152-5  0.409
1979 Cochet M, Perrin F, Gannon F, Krust A, Chambon P, Mcknight GS, Lee DC, Mayo KE, Palmiter R. Cloning of an almost full-length chicken conalbumin double-stranded cDNA Nucleic Acids Research. 6: 2435-2452. PMID 88720 DOI: 10.1093/Nar/6.7.2435  0.608
1973 Schimke RT, Palacios R, Palmiter RD, Rhoads RE. Hormonal regulation of ovalbumin synthesis in chick oviduct. Basic Life Sciences. 1: 123-35. PMID 4797927 DOI: 10.1007/978-1-4684-0877-5_10  0.607
1973 Palmiter RD, Schimke RT. Regulation of protein synthesis in chick oviduct. 3. Mechanism of ovalbumin "superinduction" by actinomycin D. The Journal of Biological Chemistry. 248: 1502-12. PMID 4694721  0.579
1972 Palmiter RD, Palacios R, Schimke RT. Identification and isolation of ovalbumin-synthesizing polysomes. II. Quantification and immunoprecipitation of polysomes. The Journal of Biological Chemistry. 247: 3296-304. PMID 4112809  0.564
1972 Palacios R, Palmiter RD, Schimke RT. Identification and isolation of ovalbumin-synthesizing polysomes. I. Specific binding of 125 I-anti-ovalbumin to polysomes. The Journal of Biological Chemistry. 247: 2316-21. PMID 4111967  0.566
1971 Palmiter RD, Oka T, Schimke RT. Modulation of ovalbumin synthesis by estradiol-17 beta and actinomycin D as studied in explants of chick oviduct in culture. The Journal of Biological Chemistry. 246: 724-37. PMID 5542686  0.577
1970 Palmiter RD, Christensen AK, Schimke RT. Organization of polysomes from pre-existing ribosomes in chick oviduct by a secondary administration of either estradiol or progesterone. The Journal of Biological Chemistry. 245: 833-45. PMID 5416666  0.57
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