MRC Laboratory of Molecular Biology

Name Area Department Start Year Stop Year Advisor
Ethan Royal Signer Sydney Brenner (post-doc)
Roger D. KornbergTranscription, Gene Regulation, Structural Biology Francis Harry Compton Crick (post-doc), Aaron Klug (post-doc)
Alexander RichDNA Structure, Structural Biology Francis Harry Compton Crick (post-doc)
Tom ManiatisRegulation of RNA Transcription and Splicing, The Role of Neuroinflammation in ALS, Neurobiology of Disease, Synapses and Circuits, Stem Cell Biology, ALS Disease Mechanisms, Genetic Basis of Neurological Diseases Frederick Sanger (post-doc)
Gerald M. Rubinstructure, function of fly genome Sydney Brenner (grad student)
Rodney Robert PorterImmunology1948 Frederick Sanger (grad student)
Sidney AltmanBiochemistry Sydney Brenner (post-doc)
John E. SulstonApoptosis, developement Sydney Brenner (research scientist)
Jamie JohnstonK channels, T-type Ca channels, calyx of Held, retina, olfactory bulb Leon Lagnado (post-doc)
Keith BurridgeCytoskeleton, Focal Adhesions Dennis Bray (grad student)
T. Martin Schmeing Venkatraman Ramakrishnan (post-doc)
Alexander N. GlazerPhycobilisome Architecture1964 Frederick Sanger (post-doc)
William S. Allisonbioenergetics; molecular mechanism of ATP synthase1966 J. Ieuan Harris (post-doc)
Elizabeth H. Blackburnstructure, function, and synthesis of telomeres1975 Frederick Sanger (grad student)
Jonathan R. Beckwithbacterial genetics1964 Sydney Brenner (post-doc)
James E. DahlbergsnRNA, mRNA splicing Frederick Sanger (post-doc)
Gérard Bricogneprotein and virus structure determination David M. Blow (grad student), Aaron Klug (post-doc)
Clarence E. Schuttstructures and roles of actin-binding proteins1985 Aaron Klug (post-doc), Hugh Esmor Huxley (post-doc)
Jonathan A. KingProtein Folding1970 Aaron Klug (post-doc)
Venkat GopalanStructure and mechanism of action of ribonuclease P, a catalytic ribonucleoprotein (RNP) complex1998 Aaron Klug (post-doc)
Andrew TraversChromatin folding and unfolding1964 John Derek Smith (grad student)
Matthew Powner John D. Sutherland (grad student)
Lee B. Mullen John D. Sutherland (grad student)
Michael Crowe John D. Sutherland (grad student)
Saidul Islam John D. Sutherland (grad student)
John W. SedatNuclear Architecture and Chromosome Organization Frederick Sanger (post-doc)
Harry F. NollerRibosome1966 J. Ieuan Harris (post-doc)
William A. EatonKinetics, dynamics, and mechanisms of protein folding1962 Sydney Brenner (research assistant)
Michael B. MathewsRegulatory RNAs; RNA–protein interactions; Novel targets for anti-HIV drugs Frederick Sanger (post-doc)
Nicholas ProudfootmRNA processing, transcription termination George G. Brownlee (grad student)
David A. AgardStructure, function, and folding of proteins, chromosomes, and centrosomes1981 Richard Henderson (post-doc)
Byung-Gil LeeStructural Biology, Protein Crystallography
Richard Perhamimmunology Frederick Sanger (grad student)
Simon Brunner Jason William Chin (post-doc), Jason William Chin (grad student)
Tiong Sun Chia Jason William Chin (post-doc)
Tom Elliott Jason William Chin (post-doc)
Russell Ernst Jason William Chin (post-doc)
Julius Fredens Jason William Chin (post-doc)
Benjami Oller Salvia Jason William Chin (post-doc)
Alexandria Liang Jason William Chin (post-doc)
Inja Radman Jason William Chin (post-doc)
Wolfgang Schmied Jason William Chin (post-doc)
Zakir Tnimov Jason William Chin (post-doc)
Fiona Townsley Jason William Chin (post-doc)
Tao Uttamapinant Jason William Chin (post-doc)
Kaihang Wang Jason William Chin (post-doc)
Shaofei Zhang Jason William Chin (post-doc)
Vaclav Beranek Jason William Chin (grad student)
Nicolas Huguenin Jason William Chin (grad student)
Julian Willis Jason William Chin (grad student)
Arnaud Gautier Jason William Chin (post-doc)
Michael Lammers Jason William Chin (post-doc)
Roger L. Williams
Sabine Petry Venkatraman Ramakrishnan (grad student)
Albert Weixlbaumer Venkatraman Ramakrishnan (grad student)
Maria Selmer Venkatraman Ramakrishnan (post-doc)
John L. RubinsteinBiochemistry Structural Studies Protein and Nucleic Acid Chemistry Richard Henderson (grad student), John E. Walker (grad student)
Patrycja Kozik Sebastian Springer (research assistant)
William R. Schafer
John D. Sutherland
Robert DiamondStructural Biology
J. Ieuan Harrisprotein chemistry
Philipp Holliger
Michael Samuel NeubergerImmunology, Antibodies Gregory Paul Winter (collaborator)
Daniela Rhodes
Sarah A. TeichmannComputational Biology
Richard J. Robertsmolecular biology1970 Frederick Sanger (post-doc)
Winship HerrMolecular epigenetics; cell-cycle; differentiation; transcription; herpes simplex virus; cancer Frederick Sanger (post-doc)
Murray Stewart
Juan B. Rodriguez MolinaTranscription and RNA processing Lori Passmore (post-doc)
Katerina Naydenova Christopher J. Russo (grad student)
Christopher J. RussoElectron Microscopy, Radiation Physics, Rapid Sequencing
Anantha KumarStructural Biology, Gene Regulation, Biochemistry
Robert Henry Symonsstructure, function and replication of plant viruses, viroids and virusoids1978 Frederick Sanger (research scientist)
Judith E. KimbleMolecular Biology, Biochemistry1983 John E. Sulston (post-doc)
Charles W Morgan
Min Kyung Kim
Sukhvinder S. BansalChemical Biology, Peptide, Organic Chemistry1989 Robert C. Sheppard (post-doc)
Claudia Bonfio2017 Sheref S. Mansy (grad student)
Jisnuson Svasti1972 César Milstein (grad student)
Meindert H. LamersDNA replication
Rob R Kay
Nicholas J. CowanMolecular Biology, Biochemistry Biochemistry César Milstein (grad student)
Max F. Perutzproteins
Frederick Sangerprotein sequencing, chemistry
John E. WalkerBiochemistry
Cemre Manav
Chayasith Uttamapinant
César MilsteinImmunology
Francis H. C.
Morten P. Meldal Robert C. Sheppard (post-doc)
Frank W. Putnamprotein chemistry19521953 Frederick Sanger (research scientist)
Michael G. RossmannX-ray crystallography, cryo electron microscopy and molecular biology to study the three dimensional structures of viruses and their component proteins19581964 Max F. Perutz (research scientist)
Kenneth C. Holmes19611968 Hugh Esmor Huxley (research scientist)
Hugh Esmor Huxleymuscle structure and function
Brian W. MatthewsX-ray crystallography, protein folding19631967 David M. Blow (post-doc)
Robert Harvey RowndDNA replication control, molecular medicine19631965 Sydney Brenner (post-doc)
Bart BarrellDNA sequencing
Paul B. Siglerregulation of gene expression mediated by proteins that bind specifically to DNA, signal transduction pathway involved in vision, structural biology19641967 David M. Blow (grad student)
Harvey F. LodishCell biology, hematology, endocrinology19661968 Francis Harry Compton Crick (post-doc), Sydney Brenner (post-doc)
Arthur Landysite-specific recombination, global regulation of cell physiology, and protein-DNA interactions19661968 Sydney Brenner (post-doc), Francis Harry Compton Crick (post-doc)
Thomas A. SteitzBiochemistry, structural chemistry19671970 David M. Blow (post-doc)
Joan A. SteitzRNA, Splicing19671970 Francis Harry Compton Crick (post-doc)
Andrew McLachlanElectron spin resonance spectroscopy, Protein structure comparison, protein evolution, gene duplication
Michael Levittcomputational structural biology19711972 Robert Diamond (grad student), Aaron Klug (post-doc)
Susan Serota TaylorStructure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase Superfamily19681971 Brian S. Hartley (post-doc)
Victor Ling19691971 Frederick Sanger (post-doc)
William H McClainMolecular Biology Cell and Molecular Biology Unit19691971 Sydney Brenner (post-doc), Francis H. C. (post-doc)
Edward Ziff19701973 Frederick Sanger (post-doc)
Gillian M. AirVirology Biology, Biochemistry19701973 Frederick Sanger (post-doc)
Samuel Wardmutants of C. elegans19711973 Sydney Brenner (post-doc)
Robert C. Sheppardpeptide, chemistry, solid phase peptide synthesis, chemical biology
Jon D. RobertusBiochemistry: Structural Biology, Protein Engineering, And Drug Design19721974 Aaron Klug (post-doc)
Gregory Paul Wintertherapeutic monoclonal antibodies humanise antibodies, using phage display, antibodies for therapeutic uses19761980 Brian S. Hartley (grad student), George G. Brownlee (post-doc)
Joel Janin19731974 David M. Blow (post-doc)
Jens Nyborgcrystallography19731975 David M. Blow (post-doc)
H. Robert HorvitzALS19741978 Sydney Brenner (post-doc)
Georges J.F. Köhler19741976 César Milstein (post-doc)
Janet E. MertzTranscriptional regulation in DNA tumor viruses and breast cancer19751976 John B. Gurdon (post-doc)
Clyde A. Hutchisonbiochemical study of DNA genomes19751976 Frederick Sanger (research scientist)
Timothy A. SpringerImmunology19761977 César Milstein (post-doc)
Timothy J. RichmondNucleosome structure19781980 Aaron Klug (post-doc)
Prescott DeiningerHuman Mobile Elements19801981 Frederick Sanger (post-doc)
Kevin StruhlTranscription19801981 Sydney Brenner (post-doc)
Alfonso Mondragónstructure and function of proteins and nucleic acids19811984 Aaron Klug (grad student)
Mary Miu Yee WAYEDyslexia, Psychiatric Diseases, Suicide, Reading & Writing, twins, KIAA0319, HBX19841986 Gregory Paul Winter (post-doc), Timothy J. Richmond (post-doc)
Andrew Zachary FireRNAi19831986 Sydney Brenner (post-doc)
Graham F. HatfullMicrobiology Biology, Biochemistry Molecualr Biology19831984 Bart Barrell (post-doc)
Hugues BedouelleProtein engineering19841986 Gregory Paul Winter (research scientist)
Christopher Winslow Akeycryo-electron microscopy Structural Studies19881990 Nigel Unwin (research scientist)
Robert DutnallBiochemistry Structural Studies19901995 Daniela Rhodes (grad student)
Gabriele VaraniNMR spectroscopy to elucidate the structure and the dynamics of protein-RNA complexes
Dario Neri19921996 Gregory Paul Winter (post-doc)
William Gregory ScottRNA structure, catalysis and the origin of life19931996 Aaron Klug (post-doc)
Brian G. AyreBiochemistry, Botany Biology, Physiology Biology Plant Biology19951998 James P. Haseloff (post-doc)
Michael E. PacoldCancer metabolism, metabolomics Protein and Nucleic Acid Chemistry19992003 Roger L. Williams (grad student)
Venkatraman RamakrishnanBiochemistry, structural chemistry
Oliver Rackham20032005 Jason William Chin (post-doc)
Jason William Chin
Benjamin OdermattCNS, Myelin, zebrafish, imaging2004 Leon Lagnado (post-doc)
Christine M. DunhamRNA structure, catalysis and the origin of life20042008 Venkatraman Ramakrishnan (post-doc)
Heinz Neumann20062009 Jason William Chin (post-doc)
Christian Heinis20062008 Gregory Paul Winter (post-doc)
Andre E. Brownbehaviour, genetics, C. elegans20092013 William R. Schafer (post-doc)
Sebastian Greiss20092014 Jason William Chin (post-doc)
Satpal Virdee20092011 Jason William Chin (post-doc)
Lori Passmore Venkatraman Ramakrishnan (post-doc)
Kathrin Lang20102014 Jason William Chin (post-doc)
Eyal Arbely20102012 Jason William Chin (post-doc)
Amit SachdevaDNA as a catalyst20112015 Jason William Chin (post-doc)
Yu-Hsuan Tsai20122014 Jason William Chin (post-doc)
Simon Elsaesser20122014 Jason William Chin (post-doc)
Shintaro Aibara Structural Studies20122015 Murray Stewart (grad student)
Stephen D. FriedBiophysics, Chemical and Synthetic Biology20142018 Jason William Chin (post-doc)
Isaac GállegoDNA biophysics, DNA nanotechnology, in vitro evolution PNAC2016 Philipp Holliger (post-doc)
Hanting Yangmembrane transport, protein synthesis, mitochondrial quality control Structural Studies20182021 Venkatraman Ramakrishnan (post-doc)
Meng Su2019 John D. Sutherland (post-doc)