Chun Pong Tam
Affiliations: | 2011- | Chemistry | Harvard University, Cambridge, MA, United States |
Area:
ChemistryGoogle:
"Chun Pong Tam"Mean distance: 39813
Collaborators
Sign in to add collaboratorAlbert C. Fahrenbach | collaborator | 2013- | Harvard Medical School |
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Publications
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Zhang W, Kim SC, Tam CP, et al. (2020) Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization. Nucleic Acids Research |
Walton T, Zhang W, Li L, et al. (2019) The mechanism of nonenzymatic template copying with imidazole-activated nucleotides. Angewandte Chemie (International Ed. in English) |
Zhang W, Tam CP, Zhou L, et al. (2018) A structural rationale for the enhanced catalysis of nonenzymatic RNA primer extension by a downstream oligonucleotide. Journal of the American Chemical Society |
Tam CP, Zhou L, Fahrenbach AC, et al. (2017) Synthesis of a nonhydrolyzable nucleotide phosphoroimidazolide analogue that catalyzes nonenzymatic RNA primer extension. Journal of the American Chemical Society |
Giurgiu C, Li L, O'Flaherty DK, et al. (2017) A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society |
Zhang W, Tam CP, Walton T, et al. (2017) Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex. Proceedings of the National Academy of Sciences of the United States of America |
Fahrenbach AC, Giurgiu C, Tam CP, et al. (2017) Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation. Journal of the American Chemical Society |
Li L, Prywes N, Tam CP, et al. (2017) Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides. Journal of the American Chemical Society |
Tam CP, Fahrenbach AC, Björkbom A, et al. (2017) Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer-Template Complexes. Journal of the American Chemical Society |
Zhang W, Tam CP, Wang J, et al. (2016) Unusual Base-Pairing Interactions in Monomer-Template Complexes. Acs Central Science. 2: 916-926 |