Brigitte Lesur

1980-1982 Chemistry  
"Brigitte Lesur"
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Lancelot N, Piotto M, Theret I, et al. (2014) Applications of NMR screening techniques to the pharmaceutical target Checkpoint kinase 1. Journal of Pharmaceutical and Biomedical Analysis. 93: 125-35
Lesur B, Lin YG, Marcy VR, et al. (2013) Aryl-heteroaryl derivatives as novel wake-promoting agents. Chemical Biology & Drug Design. 81: 429-32
Louvet P, Schweizer D, Gourdel ME, et al. (2012) Wake-promoting agents: search for next generation modafinil: part IV. European Journal of Medicinal Chemistry. 54: 949-51
Sundar BG, Bailey TR, Dunn D, et al. (2012) Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity. Bioorganic & Medicinal Chemistry Letters. 22: 1546-9
Pirotte B, Francotte P, Goffin E, et al. (2010) Ring-fused thiadiazines as core structures for the development of potent AMPA receptor potentiators. Current Medicinal Chemistry. 17: 3575-82
Vayer P, Arrault A, Lesur B, et al. (2009) [Chemoinformatics and virtual screening of molecules for therapeutic use]. MéDecine Sciences : M/S. 25: 871-7
Langer T, Hoffmann R, Bryant S, et al. (2009) Hit finding: towards 'smarter' approaches. Current Opinion in Pharmacology. 9: 589-93
Farard J, Logé C, Pfeiffer B, et al. (2009) A convenient synthesis of 5-arylamino-4H-pyran-4-ones using palladium-catalyzed amination Tetrahedron Letters. 50: 5729-5732
Legentil L, Benel L, Bertrand V, et al. (2006) Synthesis and antitumor characterization of pyrazolic analogues of the marine pyrroloquinoline alkaloids: wakayin and tsitsikammamines. Journal of Medicinal Chemistry. 49: 2979-88
Legentil L, Lesur B, Delfourne E. (2006) Aza-analogues of the marine pyrroloquinoline alkaloids wakayin and tsitsikammamines: synthesis and topoisomerase inhibition. Bioorganic & Medicinal Chemistry Letters. 16: 427-9
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