Troy Ryba

Affiliations: 
Scripps Research Institute Florida 
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"Troy Ryba"
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Thomas Robert Hoye grad student 2005 UMN
 (Efforts towards a total synthesis of (+)-peloruside A.)
William R. Roush post-doc Scripps Research Institute Florida
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Publications

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Pope BD, Ryba T, Dileep V, et al. (2014) Topologically associating domains are stable units of replication-timing regulation. Nature. 515: 402-5
Pandya BA, Dandapani S, Duvall JR, et al. (2011) Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions. Tetrahedron. 67: 6131-6137
Marcaurelle LA, Comer E, Dandapani S, et al. (2010) An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. Journal of the American Chemical Society. 132: 16962-76
Hoye TR, Jeon J, Kopel LC, et al. (2010) Total synthesis of peloruside A through kinetic lactonization and relay ring-closing metathesis cyclization reactions. Angewandte Chemie (International Ed. in English). 49: 6151-5
Ryba TD, Depew KM, Marcaurelle LA. (2009) Large scale preparation of silicon-functionalized SynPhase Polystyrene lanterns for solid-phase synthesis. Journal of Combinatorial Chemistry. 11: 110-6
Hoye TR, Kopel LC, Ryba TD. (2006) In situ generation and nucleophilic capture of 1,n-dial equivalents from 1,n-dioates (α,ω-diesters) Synthesis. 1572-1574
Hoye TR, Ryba TD. (2005) Divergent kinetic control of classical versus ozonolytic lactonization: mechanism-based diastereoselection. Journal of the American Chemical Society. 127: 8256-7
Hoye TR, Aspaas AW, Eklov BM, et al. (2005) Reaction titration: a convenient method for titering reactive hydride agents (Red-Al, LiAlH4, DIBALH, L-Selectride, NaH, and KH) by No-D NMR spectroscopy. Organic Letters. 7: 2205-8
Hoye TR, Eklov BM, Ryba TD, et al. (2004) No-D NMR (no-deuterium proton NMR) spectroscopy: a simple yet powerful method for analyzing reaction and reagent solutions. Organic Letters. 6: 953-6
Ryba TD, Harran PG. (2000) Two useful photolabile surfaces for solid-phase synthesis Organic Letters. 2: 851-853
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