Yen Ting Chen

Affiliations: 
Scripps Research Institute Florida 
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"Yen Chen"
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Kennedy NM, Schmid CL, Ross NC, et al. (2018) Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. Journal of Medicinal Chemistry
Li J, Huang J, Jeong JH, et al. (2014) Selective TBK1/IKKi dual inhibitors with anticancer potency. International Journal of Cancer. Journal International Du Cancer. 134: 1972-80
Andero R, Brothers SP, Jovanovic T, et al. (2013) Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Science Translational Medicine. 5: 188ra73
Chowdhury S, Chen YT, Fang X, et al. (2013) Amino acid derived quinazolines as Rock/PKA inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 1592-9
Chen YT, Brinen LS, Kerr ID, et al. (2013) Structure of WRR-483 bound to cruzain Plos Neglected Tropical Diseases
Zhou Y, Agudelo J, Lu K, et al. (2011) Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. Antiviral Research. 92: 187-94
Fang X, Chen YT, Sessions EH, et al. (2011) Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1844-8
Chen YT, Vojkovsky T, Fang X, et al. (2011) Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors Medchemcomm. 2: 73-75
Yin Y, Cameron MD, Lin L, et al. (2010) Discovery of Potent and Selective Urea-Based ROCK Inhibitors and Their Effects on Intraocular Pressure in Rats. Acs Medicinal Chemistry Letters. 1: 175-9
Chen YT, Brinen LS, Kerr ID, et al. (2010) In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. Plos Neglected Tropical Diseases. 4
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