Andrew Coop, Ph.D.

Affiliations: 
1999- Pharmaceutical Sciences University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Opioid synthesis
Website:
http://faculty.rx.umaryland.edu/acoop/
Google:
"Andrew Coop"
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Publications

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Healy JR, Bezawada P, Griggs NW, et al. (2016) Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta opioid receptor ligands. Bioorganic & Medicinal Chemistry Letters
Huang J, Lakkaraju SK, Coop A, et al. (2016) Conformational Heterogeneity of Intracellular Loop 3 of the µ-Opioid G-Protein Coupled Receptor. The Journal of Physical Chemistry. B
Cavalier MC, Ansari MI, Pierce AD, et al. (2016) Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations. Journal of Medicinal Chemistry
Ben Haddou T, Malfacini D, Calo G, et al. (2014) Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor. Molecular Pain. 10: 48
Metcalf MD, Rosicky AD, Hassan HE, et al. (2014) Opioids and efflux transporters. Part 4: influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues. Bioorganic & Medicinal Chemistry Letters. 24: 3592-5
Motel WC, Healy JR, Viard E, et al. (2013) Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands. Bioorganic & Medicinal Chemistry Letters. 23: 6920-2
Stavitskaya L, Seminerio MJ, Healy JR, et al. (2013) Effect of ring-constrained phenylpropyloxyethylamines on sigma receptors. Bioorganic & Medicinal Chemistry. 21: 4923-7
Shim J, Coop A, MacKerell AD. (2013) Molecular details of the activation of the μ opioid receptor. The Journal of Physical Chemistry. B. 117: 7907-17
Robson MJ, Seminerio MJ, McCurdy CR, et al. (2013) σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation. Pharmacological Reports : Pr. 65: 343-9
Healy JR, Bezawada P, Shim J, et al. (2013) Synthesis, modeling, and pharmacological evaluation of UMB 425, a mixed μ agonist/δ antagonist opioid analgesic with reduced tolerance liabilities. Acs Chemical Neuroscience. 4: 1256-66
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