Qinheng Zheng, Ph.D.
Affiliations: | 2010-2014 | College of Chemistry and Molecular Engineering | Peking University, Beijing, Beijing Shi, China |
2014-2020 | Department of Chemistry | Scripps Research Institute, La Jolla, La Jolla, CA, United States | |
2020- | Department of Cellular and Molecular Pharmacology | University of California, San Francisco, San Francisco, CA |
Area:
ChemistryGoogle:
"Qinheng Zheng"Mean distance: 39813
Parents
Sign in to add mentorZhi-Xiang Yu | research assistant | 2012-2014 | Peking University |
K. Barry Sharpless | grad student | 2014- | Scripps Institute |
Kevan Michael Shokat | post-doc | 2020- | UCSF |
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Publications
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Zheng Q, Zhang Z, Guiley KZ, et al. (2024) Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature Chemical Biology |
Malakoutikhah M, Mahran R, Gooran N, et al. (2023) Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes. Analytical Chemistry |
Vasta JD, Peacock DM, Zheng Q, et al. (2022) KRAS is vulnerable to reversible switch-II pocket engagement in cells. Nature Chemical Biology |
Zheng Q, Peacock DM, Shokat KM. (2022) Drugging the Next Undruggable KRAS Allele-Gly12Asp. Journal of Medicinal Chemistry |
Garnar-Wortzel L, Bishop TR, Kitamura S, et al. (2021) Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia. Acs Central Science. 7: 815-830 |
Zheng Q, Xu H, Wang H, et al. (2021) Sulfur [F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis. Journal of the American Chemical Society |
Kitamura S, Zheng Q, Woehl JL, et al. (2020) SuFEx-enabled high-throughput medicinal chemistry. Journal of the American Chemical Society |
Zheng Q, Woehl JL, Kitamura S, et al. (2019) SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proceedings of the National Academy of Sciences of the United States of America |
Barrow AS, Smedley CJ, Zheng Q, et al. (2019) The growing applications of SuFEx click chemistry. Chemical Society Reviews |
Smedley CJ, Zheng Q, Gao B, et al. (2019) Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angewandte Chemie (International Ed. in English) |