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Kent S. Gates, Ph.D.

Affiliations: 
1993- Chemistry University of Missouri, Columbia, MO 
Area:
Medicinal Chemistry
Website:
http://faculty.missouri.edu/~gatesk/index.html
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"Kent Gates"
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Publications

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Wyatt JW, Korasick DA, Qureshi IA, et al. (2020) Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1. Archives of Biochemistry and Biophysics. 108477
Campbell AC, Becker DF, Gates KS, et al. (2020) Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. Acs Chemical Biology
Laciak AR, Korasick DA, Gates KS, et al. (2019) Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. Journal of Inherited Metabolic Disease
Laciak AR, Korasick DA, Wyatt JW, et al. (2019) Structural and Biochemical Consequences of Pyridoxine-Dependent Epilepsy Mutations That Target the Aldehyde Binding Site of Aldehyde Dehydrogenase ALDH7A1. The Febs Journal
Nejad MI, Price NE, Haldar T, et al. (2019) Interstrand DNA Cross-Links Derived from Reaction of a 2-Aminopurine Residue with an Abasic Site. Acs Chemical Biology
Nejad MI, Guo X, Housh K, et al. (2019) Preparation and Purification of Oligodeoxynucleotide Duplexes Containing a Site-Specific, Reduced, Chemically Stable Covalent Interstrand Cross-Link Between a Guanine Residue and an Abasic Site. Methods in Molecular Biology (Clifton, N.J.). 1973: 163-175
Shen X, Laber CH, Sarkar U, et al. (2018) Exploiting the inherent photophysical properties of the major tirapazamine metabolite in the development of profluorescent substrates for enzymes that catalyze the bioreductive activation of hypoxia-selective anticancer prodrugs. The Journal of Organic Chemistry
Korasick D, Wyatt J, Luo M, et al. (2017) Importance of the C-terminus of ALDH7A1 for Oligomerization and Catalytic Activity. Biochemistry
Wang Y, Tian K, Shi R, et al. (2017) Nanolock-Nanopore Facilitated Digital Diagnostics of Cancer Driver Mutation in Tumor Tissue. Acs Sensors. 2: 975-981
Yang Z, Price NE, Johnson KM, et al. (2017) Interstrand cross-links arising from strand breaks at true abasic sites in duplex DNA. Nucleic Acids Research
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