Kent S. Gates, Ph.D.

1993- Chemistry University of Missouri, Columbia, MO 
Medicinal Chemistry
"Kent Gates"
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Wyatt JW, Korasick DA, Qureshi IA, et al. (2020) Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1. Archives of Biochemistry and Biophysics. 108477
Campbell AC, Becker DF, Gates KS, et al. (2020) Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. Acs Chemical Biology
Laciak AR, Korasick DA, Gates KS, et al. (2019) Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. Journal of Inherited Metabolic Disease
Laciak AR, Korasick DA, Wyatt JW, et al. (2019) Structural and Biochemical Consequences of Pyridoxine-Dependent Epilepsy Mutations That Target the Aldehyde Binding Site of Aldehyde Dehydrogenase ALDH7A1. The Febs Journal
Korasick D, Wyatt J, Luo M, et al. (2017) Importance of the C-terminus of ALDH7A1 for Oligomerization and Catalytic Activity. Biochemistry
Punthasee P, Laciak AR, Cummings AH, et al. (2017) Covalent allosteric inactivation of PTP1B by an inhibitor-electrophile conjugate. Biochemistry
Ruddraraju KV, Parsons ZD, Lewis CD, et al. (2017) Correction to "Allylation and Alkylation of Biologically Relevant Nucleophiles by Diallyl Sulfides". The Journal of Organic Chemistry
Viswanatharaju Ruddraraju K, Parsons ZD, Lewis CD, et al. (2016) Allylation and Alkylation of Biologically Relevant Nucleophiles by Diallyl Sulfides. The Journal of Organic Chemistry
Catalano MJ, Ruddraraju KV, Barnes CL, et al. (2016) Crystal structure of a nucleoside model for the inter-strand cross-link formed by the reaction of 2'-de-oxy-guanosine and an abasic site in duplex DNA. Acta Crystallographica. Section E, Crystallographic Communications. 72: 624-7
Parsons ZD, Ruddraraju KV, Santo N, et al. (2016) Sulfone-stabilized carbanions for the reversible covalent capture of a posttranslationally-generated cysteine oxoform found in protein tyrosine phosphatase 1B (PTP1B). Bioorganic & Medicinal Chemistry
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