James M. Cook, Ph.D.
Affiliations: | 1973- | Chemistry | University of Wisconsin-Milwaukee, Milwaukee, WI |
Area:
Alkaloid total synthesisWebsite:
http://alchemy.chem.uwm.edu/research/cook/Google:
"James" Cook "alkaloids"Bio:
https://pantherfile.uwm.edu/capncook/www/jmc_chem_vit.pdf
https://scholar.google.com/citations?hl=en&user=W9KC0FsAAAAJ
Mean distance: 7.17 | S | N | B | C | P |
Parents
Sign in to add mentorPhilip LeQuesne | grad student | 1968-1971 | University of Michigan | |
(I. Alkaloidal N-Oxides in Hallucinogenic Drugs. II. Studies on the Alkaloids of Alstonia muelleriana Domin) | ||||
James P. Kutney | post-doc | 1972-1973 | UBC |
Children
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Publications
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Rajaratnam V, Islam MM, Kub EF, et al. (2023) Development and validation of an LC-MS/MS method for the determination of ARN14988, an acid ceramidase inhibitor, and its application to a pharmacokinetic study in a mouse model. Biomedical Chromatography : Bmc. e5754 |
Mitrović JR, Bjelošević Žiberna M, Vukadinović A, et al. (2023) Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 189: 106557 |
Huang YH, Lee MT, Hsueh HY, et al. (2023) Cerebellar α6GABA Receptors as a Therapeutic Target for Essential Tremor: Proof-of-Concept Study with Ethanol and Pyrazoloquinolinones. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics |
Mitrović JR, Divović-Matović B, Knutson DE, et al. (2023) High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. International Journal of Pharmaceutics. 633: 122613 |
Pareek T, Overton JS, Nguyen LT, et al. (2022) Modeling cue-exposure therapy for alcohol use disorder in rhesus monkeys: Effects of putative cognitive enhancers. Drug and Alcohol Dependence. 243: 109735 |
Lee MT, Mouri A, Kubota H, et al. (2022) Targeting α6GABA receptors as a novel therapy for schizophrenia: A proof-of-concept preclinical study using various animal models. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 150: 113022 |
Rahman MT, Tiruveedhula VVNPB, Stephen MR, et al. (2022) Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor -Methyltalpinine. Molecules (Basel, Switzerland). 27 |
Souza AJ, Cortez IL, Silva NR, et al. (2022) Distinct sex-dependent behavioral responses induced by two positive allosteric modulators of alpha 5 subunit-containing GABA receptors. Behavioural Brain Research. 113832 |
Witkin JM, Lippa A, Smith JL, et al. (2022) The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders. Pharmacology, Biochemistry, and Behavior. 213: 173321 |
Roni MSR, Zahn NM, Mikulsky BN, et al. (2021) Identification and Quantification of MIDD0301 metabolites. Current Drug Metabolism |