James M. Cook, Ph.D.
|1973-||Chemistry||University of Wisconsin-Milwaukee, Milwaukee, WI|
Area:Alkaloid total synthesis
Google:"James" Cook "alkaloids"
Mean distance: 7.17
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|Mitrović JR, Bjelošević Žiberna M, Vukadinović A, et al. (2023) Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 189: 106557|
|Huang YH, Lee MT, Hsueh HY, et al. (2023) Cerebellar α6GABA Receptors as a Therapeutic Target for Essential Tremor: Proof-of-Concept Study with Ethanol and Pyrazoloquinolinones. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics|
|Mitrović JR, Divović-Matović B, Knutson DE, et al. (2023) High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. International Journal of Pharmaceutics. 633: 122613|
|Pareek T, Overton JS, Nguyen LT, et al. (2022) Modeling cue-exposure therapy for alcohol use disorder in rhesus monkeys: Effects of putative cognitive enhancers. Drug and Alcohol Dependence. 243: 109735|
|Lee MT, Mouri A, Kubota H, et al. (2022) Targeting α6GABA receptors as a novel therapy for schizophrenia: A proof-of-concept preclinical study using various animal models. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 150: 113022|
|Rahman MT, Tiruveedhula VVNPB, Stephen MR, et al. (2022) Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor -Methyltalpinine. Molecules (Basel, Switzerland). 27|
|Souza AJ, Cortez IL, Silva NR, et al. (2022) Distinct sex-dependent behavioral responses induced by two positive allosteric modulators of alpha 5 subunit-containing GABA receptors. Behavioural Brain Research. 113832|
|Witkin JM, Lippa A, Smith JL, et al. (2022) The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders. Pharmacology, Biochemistry, and Behavior. 213: 173321|
|Roni MSR, Zahn NM, Mikulsky BN, et al. (2021) Identification and Quantification of MIDD0301 metabolites. Current Drug Metabolism|
|Cerne R, Lippa A, Poe MM, et al. (2021) GABAkines - Advances in the discovery, development, and commercialization of positive allosteric modulators of GABA receptors. Pharmacology & Therapeutics. 108035|