Xiaoxiang Liu

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2002 Chemistry University of Wisconsin-Milwaukee, Milwaukee, WI 
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"Xiaoxiang Liu"
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James M. Cook grad student 2002 UW-Milwaukee
 (The enantiospecific stereospecific total synthesis of the enantiomers of the indole alkaloids N(a)-methylvellosimine, affinisine and macroline as well as the total synthesis of the indole alkaloids triervine, alstophylline and the antimalarial bisindole m)
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Jain HD, Zhang C, Zhou S, et al. (2008) Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein. Bioorganic & Medicinal Chemistry. 16: 4626-51
Han D, Försterling FH, Deschamps JR, et al. (2007) Conformational analysis of the cis- and trans-adducts of the Pictet - Spengler reaction. Evidence for the structural basis for the C(1) - N(2) scission process in the cis- to trans-isomerization. Journal of Natural Products. 70: 75-82
Liu X, Hartwig JF. (2004) Palladium-catalyzed arylation of trimethylsilyl enolates of esters and imides. High functional group tolerance and stereoselective synthesis of alpha-aryl carboxylic acid derivatives. Journal of the American Chemical Society. 126: 5182-91
Hama T, Liu X, Culkin DA, et al. (2003) Palladium-catalyzed alpha-arylation of esters and amides under more neutral conditions. Journal of the American Chemical Society. 125: 11176-7
Yu J, Wang T, Liu X, et al. (2003) General approach for the synthesis of sarpagine indole alkaloids. Enantiospecific total synthesis of (+)-vellosimine, (+)-normacusine B, (-)-alkaloid Q3, (-)-panarine, (+)-Na-methylvellosimine, and (+)-Na-methyl-16-epipericyclivine. The Journal of Organic Chemistry. 68: 7565-81
Liu X, Hartwig JF. (2003) Palladium-catalyzed alpha-arylation of azlactones to form quaternary amino acid derivatives. Organic Letters. 5: 1915-8
Cao H, Yu J, Wearing XZ, et al. (2003) The first enantiospecific synthesis of (-)-koumidine via the intramolecular palladium-catalyzed enolate driven cross coupling reaction. The stereospecific introduction of the 19-(Z) ethylidene side chain Tetrahedron Letters. 44: 8013-8017
Jørgensen M, Lee S, Liu X, et al. (2002) Efficient synthesis of alpha-aryl esters by room-temperature palladium-catalyzed coupling of aryl halides with ester enolates. Journal of the American Chemical Society. 124: 12557-65
Liu X, Deschamp JR, Cook JM. (2002) Regiospecific, enantiospecific total synthesis of the alkoxy-substituted indole bases, 16-epi-N(a)-methylgardneral, 11-methoxyaffinisine, and 11-methoxymacroline as well as the indole alkaloids alstophylline and macralstonine. Organic Letters. 4: 3339-42
Liu X, Zhang C, Liao X, et al. (2002) Enantiospecific total synthesis of the enantiomer of the indole alkaloid intermediate macroline Tetrahedron Letters. 43: 7373-7377
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