Joshua Michener

Affiliations: 
2015- Biosciences Oak Ridge National Laboratory, Oak Ridge, TN, United States 
Website:
michenerlab.org
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"Joshua Michener"
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Christina D. Smolke grad student 2006-2012 Caltech
 (Combining Rational and Evolutionary Approaches to Optimize Enzyme Activity in Saccharomyces cerevisiae.)
Christopher J. Marx post-doc 2012-2014 Harvard (Evolution Tree)
Eric J. Alm post-doc 2014-2015 MIT (BME Tree)
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Publications

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Close DM, Cooper CJ, Wang X, et al. (2019) Horizontal transfer of a pathway for coumarate catabolism unexpectedly inhibits purine nucleotide biosynthesis. Molecular Microbiology
Chaves JE, Presley GN, Michener JK. (2019) Modular Engineering of Biomass Degradation Pathways Processes. 7: 230
Cecil JH, Garcia DC, Giannone RJ, et al. (2018) Rapid, parallel identification of pathways for catabolism of lignin-derived aromatic compounds in . Applied and Environmental Microbiology
Standaert RF, Giannone RJ, Michener JK. (2018) Identification of parallel and divergent optimization solutions for homologous metabolic enzymes. Metabolic Engineering Communications. 6: 56-62
Clarkson SM, Giannone RJ, Kridelbaugh DM, et al. (2017) Construction and optimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli enables bioconversion of model aromatic compounds. Applied and Environmental Microbiology
Michener JK, Vuilleumier S, Bringel F, et al. (2016) Transfer of a Catabolic Pathway for Chloromethane in Methylobacterium Strains Highlights Different Limitations for Growth with Chloromethane or with Dichloromethane. Frontiers in Microbiology. 7: 1116
Houser JR, Barnhart C, Boutz DR, et al. (2015) Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation. Plos Computational Biology. 11: e1004400
Houser JR, Barnhart C, Boutz DR, et al. (2015) Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation Plos Computational Biology. 11
Michener JK, Marx CJ. (2015) After horizontal gene transfers, metabolic pathways may need further optimization: Effective use of a horizontally transferred pathway can require co-evolutionary changes in the host or pathway Microbe. 10: 61-67
Michener JK, Camargo Neves AA, Vuilleumier S, et al. (2014) Effective use of a horizontally-transferred pathway for dichloromethane catabolism requires post-transfer refinement. Elife. 3
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