David J. Brunell, Ph.D.

Affiliations: 
Florida Atlantic University, Boca Raton, FL, United States 
Area:
protection against oxidative damage and specifically the role of the methionine sulfoxide reductase system in this process
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Herbert Weissbach grad student 2009 Florida Atlantic University
 (Methionine sulfoxide reductases: Studies on the reducing requirements and role in the metabolism of sulindac.)
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Brunell D, Sagher D, Kesaraju S, et al. (2011) Studies on the metabolism and biological activity of the epimers of sulindac Drug Metabolism and Disposition. 39: 1014-1021
Brunell D, Weissbach H, Hodder P, et al. (2010) A high-throughput screening compatible assay for activators and inhibitors of methionine sulfoxide reductase A Assay and Drug Development Technologies. 8: 615-620
Brunell DJ, Lowther T, Sagher D, et al. (2007) A disulfide intermediate is required for the reduction of methionine sulfoxide reductase by thioredoxin The Faseb Journal. 21
Sagher D, Brunell D, Brot N, et al. (2006) Selenocompounds can serve as oxidoreductants with the methionine sulfoxide reductase enzymes Journal of Biological Chemistry. 281: 31184-31187
Sagher D, Brunell D, Hejtmancik JF, et al. (2006) Thionein can serve as a reducing agent for the methionine sulfoxide reductases Proceedings of the National Academy of Sciences of the United States of America. 103: 8656-8661
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