Masha Poyurovsky, Ph.D.

Affiliations: 
Columbia University, New York, NY 
Area:
p53 tumour suppressor protein
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"Masha Poyurovsky"
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Parents

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Carol L. Prives grad student 2005 Columbia
 (Biochemical and molecular studies of the Mdm2 RING domain.)
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Publications

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Zanin-Zhorov A, Weiss JM, Nyuydzefe MS, et al. (2014) Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 111: 16814-9
Poyurovsky MV, Prives C. (2014) P53: Guardian of the metabolome P53 in the Clinics. 47-64
Hosokawa H, Tanaka T, Kato M, et al. (2013) Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression. Proceedings of the National Academy of Sciences of the United States of America. 110: 18626-31
Poyurovsky MV. (2012) Length matters: C-terminal tails regulate Mdm2-MdmX complexes. Cell Cycle (Georgetown, Tex.). 11: 1485
Biderman L, Poyurovsky MV, Assia Y, et al. (2012) MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress. Molecular and Cellular Biology. 32: 1214-25
Herman AG, Hayano M, Poyurovsky MV, et al. (2011) Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. Cancer Discovery. 1: 312-25
Peart MJ, Poyurovsky MV, Kass EM, et al. (2010) APC/C(Cdc20) targets E2F1 for degradation in prometaphase. Cell Cycle (Georgetown, Tex.). 9: 3956-64
Priest C, Prives C, Poyurovsky MV. (2010) Deconstructing nucleotide binding activity of the Mdm2 RING domain Nucleic Acids Research. 38: 7587-7598
Poyurovsky MV, Prives C. (2010) P53 and aging: A fresh look at an old paradigm. Aging. 2: 380-2
Poyurovsky MV, Katz C, Laptenko O, et al. (2010) The C terminus of p53 binds the N-terminal domain of MDM2. Nature Structural & Molecular Biology. 17: 982-9
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