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Rachel A. Beckerman, Ph.D.

Affiliations: 
Columbia University, New York, NY 
Area:
p53 tumour suppressor protein
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"Rachel Beckerman"
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Parents

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Carol L. Prives grad student 2009 Columbia
 (Mechanisms of regulation within the p53 transcriptional program.)

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Publications

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Beckerman R, Yoh K, Mattia-Sansobrino M, et al. (2016) Lysines in the tetramerization domain of p53 selectively modulate G1 arrest. Cell Cycle (Georgetown, Tex.). 1-14
Barsotti AM, Beckerman R, Laptenko O, et al. (2012) p53-Dependent induction of PVT1 and miR-1204. The Journal of Biological Chemistry. 287: 2509-19
Huggins P, Zhong S, Shiff I, et al. (2011) DECOD: fast and accurate discriminative DNA motif finding. Bioinformatics (Oxford, England). 27: 2361-7
Laptenko O, Beckerman R, Freulich E, et al. (2011) p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 108: 10385-90
Poyurovsky MV, Katz C, Laptenko O, et al. (2011) Erratum: The C terminus of p53 binds the N-terminal domain of MDM2 Nature Structural & Molecular Biology. 18: 516-516
Beckerman R, Prives C. (2010) Transcriptional regulation by p53. Cold Spring Harbor Perspectives in Biology. 2: a000935
Poyurovsky MV, Katz C, Laptenko O, et al. (2010) The C terminus of p53 binds the N-terminal domain of MDM2. Nature Structural & Molecular Biology. 17: 982-9
Prives C, Barsotti AM, Beckerman R, et al. (2010) 636 Mechanisms by which the p53 tumour suppressor protein selects its target genes Ejc Supplements. 8: 161
Beckerman R, Donner AJ, Mattia M, et al. (2009) A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint. Genes & Development. 23: 1364-77
Ahn J, Poyurovsky MV, Baptiste N, et al. (2009) Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein. Cell Cycle (Georgetown, Tex.). 8: 1603-15
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