Anthony M. Barsotti, Ph.D.
Affiliations: | Biological Sciences | Columbia University, New York, NY |
Area:
p53 tumour suppressor proteinGoogle:
"Anthony Barsotti"Mean distance: 12.26 | S | N | B | C | P |
Parents
Sign in to add mentor| Carol L. Prives | grad student | 2011 | Columbia | |
| (Negative regulation of gene expression by the tumor suppressor p53.) | ||||
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Publications
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| Olszewski K, Barsotti A, Feng XJ, et al. (2021) Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors. Cell Chemical Biology |
| Liu KG, Kim JI, Olszewski K, et al. (2020) Discovery and Optimization of Glucose Uptake Inhibitors. Journal of Medicinal Chemistry |
| Moon SH, Huang CH, Houlihan SL, et al. (2018) p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell |
| Singer S, Zhao R, Barsotti AM, et al. (2012) Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Molecular Cell. 48: 799-810 |
| Freed-Pastor WA, Mizuno H, Zhao X, et al. (2012) Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell. 148: 244-58 |
| Barsotti AM, Beckerman R, Laptenko O, et al. (2012) p53-Dependent induction of PVT1 and miR-1204. The Journal of Biological Chemistry. 287: 2509-19 |
| Barsotti AM, Prives C. (2010) Noncoding RNAs: the missing "linc" in p53-mediated repression. Cell. 142: 358-60 |
| Barsotti AM, Prives C. (2009) Pro-proliferative FoxM1 is a target of p53-mediated repression. Oncogene. 28: 4295-305 |
| Baptiste-Okoh N, Barsotti AM, Prives C. (2008) Caspase 2 is both required for p53-mediated apoptosis and downregulated by p53 in a p21-dependent manner. Cell Cycle (Georgetown, Tex.). 7: 1133-8 |
| Baptiste-Okoh N, Barsotti AM, Prives C. (2008) A role for caspase 2 and PIDD in the process of p53-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 1937-42 |