Chien P. Chen, Ph.D.

computational biophysics and bioinformatics

Barry H. Honig	grad student	2006	Columbia
(Theoretical and experimental insights into specificity determinants and molecular mechanisms of cadherin mediated adhesion.)

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Chen YY, Chuang PY, Chen CP, et al. (2014) Functional antagonism between high temperature requirement protein A (HtrA) family members regulates trophoblast invasion. The Journal of Biological Chemistry. 289: 22958-68
Patel SD, Ciatto C, Chen CP, et al. (2006) Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell. 124: 1255-68
Chen CP, Posy S, Ben-Shaul A, et al. (2005) Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping. Proceedings of the National Academy of Sciences of the United States of America. 102: 8531-6
May C, Doody JF, Abdullah R, et al. (2005) Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature. Blood. 105: 4337-44
Patel SD, Chen CP, Bahna F, et al. (2003) Cadherin-mediated cell-cell adhesion: sticking together as a family. Current Opinion in Structural Biology. 13: 690-8