Zhilei Chen, Ph.D.

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Directed evolution, metabolic engineering, natural product, gene therapy, synthetic biology
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"Zhilei Chen"
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Parents

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Huimin Zhao grad student 2006 UIUC
 (Protein engineering via in vitro coevolution.)
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Publications

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Thomas B, Chockalingam K, Chen Z. (2023) Methods for Engineering Binders to Multi-Pass Membrane Proteins. Bioengineering (Basel, Switzerland). 10
Zeng Y, Woolley M, Chockalingam K, et al. (2023) Click display: a rapid and efficient in vitro protein display method for directed evolution. Nucleic Acids Research
Chockalingam K, Kumar A, Song J, et al. (2022) Chicken-derived CD20 antibodies with potent B-cell depletion activity. British Journal of Haematology
Chockalingam K, Peng Z, Vuong CN, et al. (2020) Golden Gate assembly with a bi-directional promoter (GBid): A simple, scalable method for phage display Fab library creation. Scientific Reports. 10: 2888
Heinzelman P, Low A, Simeon R, et al. (2019) De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions. Journal of Biological Engineering. 13: 76
Simeon R, Jiang M, Chamoun-Emanuelli AM, et al. (2019) Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B. Plos Biology. 17: e3000311
Kasaraneni N, Chamoun-Emanuelli AM, Wright GA, et al. (2018) A simple strategy for retargeting lentiviral vectors to desired cell types via a disulfide-bond-forming protein-peptide pair. Scientific Reports. 8: 10990
Kasaraneni N, Chamoun-Emanuelli AM, Wright G, et al. (2017) Retargeting Lentiviruses via SpyCatcher-SpyTag Chemistry for Gene Delivery into Specific Cell Types. Mbio. 8
Simeon R, Chen Z. (2017) In vitro-engineered non-antibody protein therapeutics. Protein & Cell
Ramirez MA, Chen Z. (2017) Split-Intein Triggered Protein Hydrogels. Methods in Molecular Biology (Clifton, N.J.). 1495: 161-171
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