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Shian-Huey Chiang, Ph.D.

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
diabetes, receptors, signal transduction
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"Shian-Huey Chiang"
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Alan R. Saltiel grad student 2001 University of Michigan
 (Signaling pathways involved in insulin -stimulated glucose transport.)

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Publications

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Ichikawa T, Kita M, Matsui TS, et al. (2017) Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. Journal of Cell Science
Uhm M, Bazuine M, Zhao P, et al. (2017) Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking. Science Signaling. 10
Mowers J, Uhm M, Reilly SM, et al. (2013) Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1. Elife. 2: e01119
Reilly SM, Chiang SH, Decker SJ, et al. (2013) An inhibitor of the protein kinases TBK1 and IKK-É› improves obesity-related metabolic dysfunctions in mice. Nature Medicine. 19: 313-21
Mowers J, Uhm M, Reilly SM, et al. (2013) Author response: Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1 Elife
Chiang SH, Bazuine M, Lumeng CN, et al. (2009) The protein kinase IKKepsilon regulates energy balance in obese mice. Cell. 138: 961-75
Lodhi IJ, Bridges D, Chiang SH, et al. (2008) Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5. Molecular Biology of the Cell. 19: 2718-28
Cha HC, Oak NR, Kang S, et al. (2008) Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes. The Journal of Biological Chemistry. 283: 18002-11
Chen XW, Leto D, Chiang SH, et al. (2007) Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c. Developmental Cell. 13: 391-404
Lesniewski LA, Hosch SE, Neels JG, et al. (2007) Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Nature Medicine. 13: 455-62
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