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Xiao-wei Chen, Ph.D.

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
diabetes, receptors, signal transduction
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"Xiao-wei Chen"
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Parents

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Alan R. Saltiel grad student 2008 University of Michigan
 (Coordination of cell signaling and transport machinery during insulin-stimulated glucose transport.)

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Publications

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Su L, Zhou L, Chen FJ, et al. (2019) Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. The Embo Journal
Emmer BT, Hesketh GG, Kotnik E, et al. (2018) The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9. Elife. 7
Skorobogatko Y, Dragan M, Cordon C, et al. (2018) RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America
Nie C, Chen XW. (2015) Recycling of the insulin-responsive glucose transporter Glut4 regulated by the small GTPase RalA and the exocyst complex. Methods in Cell Biology. 130: 307-18
Karunanithi S, Xiong T, Uhm M, et al. (2014) A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. Molecular Biology of the Cell. 25: 3059-69
Liu S, Xu R, Gerin I, et al. (2014) SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling. Plos One. 9: e95416
Martin TD, Chen XW, Kaplan RE, et al. (2014) Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion. Molecular Cell. 53: 209-20
Leto D, Uhm M, Williams A, et al. (2013) Negative regulation of the RalGAP complex by 14-3-3. The Journal of Biological Chemistry. 288: 9272-83
Li S, Chen XW, Yu L, et al. (2011) Circadian metabolic regulation through crosstalk between casein kinase 1δ and transcriptional coactivator PGC-1α. Molecular Endocrinology (Baltimore, Md.). 25: 2084-93
Chen XW, Saltiel AR. (2011) Ral's engagement with the exocyst: breaking up is hard to do. Cell Cycle (Georgetown, Tex.). 10: 2299-304
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