Brent K. Rubio, Ph.D.

Affiliations: 
University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
chemistry of tropical marine sponges and marine-derived fungi
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"Brent Rubio"
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Parents

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Phillip Crews grad student 2008 UC Santa Cruz
 (Bioactive natural products for global health from Papua New Guinea marine sponges.)
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Publications

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Rubio BK, Parrish SM, Yoshida W, et al. (2010) Depsipeptides from a Guamanian Marine Cyanobacterium, Lyngbya bouillonii, with Selective Inhibition of Serine Proteases. Tetrahedron Letters. 51: 6718-6721
Fisch KM, Gurgui C, Heycke N, et al. (2009) Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting. Nature Chemical Biology. 5: 494-501
Rubio BK, Tenney K, Ang KH, et al. (2009) The marine sponge Diacarnus bismarckensis as a source of peroxiterpene inhibitors of Trypanosoma brucei, the causative agent of sleeping sickness Journal of Natural Products. 72: 218-222
Rubio BK, Robinson SJ, Avalos CE, et al. (2008) Revisiting the sponge sources, stereostructure, and biological activity of cyclocinamide A Journal of Natural Products. 71: 1475-1478
Rubio BK, Van Soest RWM, Crews P. (2007) Extending the record of meroditerpenes from Cacospongia marine sponges Journal of Natural Products. 70: 628-631
Casaschi A, Rubio BK, Maiyoh GK, et al. (2004) Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: potential role in the regulation of apolipoprotein B secretion. Atherosclerosis. 176: 247-53
Casaschi A, Maiyoh GK, Rubio BK, et al. (2004) The chalcone xanthohumol inhibits triglyceride and apolipoprotein B secretion in HepG2 cells. The Journal of Nutrition. 134: 1340-6
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