Aaron T. Wecksler, Ph.D.

Affiliations: 
University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
lipoxygenase
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"Aaron Wecksler"
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SNBCP

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Theodore R. Holman grad student 2009 UC Santa Cruz
 (Allosteric, mechanistic, and inhibitory investigations of human platelet 12-lipoxygenase, human reticulocyte 15-lipoxygenase-1 and human epithelial 15-lipoxygenase-2.)
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Publications

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Garcia NK, Deperalta G, Wecksler AT. (2018) Current Trends in Biotherapeutic Higher Order Structure Characterization by Irreversible Covalent Footprinting Mass Spectrometry. Protein and Peptide Letters
Lin M, Krawitz D, Callahan MD, et al. (2018) Characterization of ELISA Antibody-Antigen Interaction using Footprinting-Mass Spectrometry and Negative Staining Transmission Electron Microscopy. Journal of the American Society For Mass Spectrometry
Wecksler AT, Yin J, Lee Tao P, et al. (2018) Photo-Disruption of the Structurally Conserved Cys-Cys-Trp Triads Leads to Reduction-Resistant Scrambled Intrachain Disulfides in an IgG1 Monoclonal Antibody. Molecular Pharmaceutics
Zhang Y, Wecksler AT, Molina P, et al. (2017) Mapping the Binding Interface of VEGF and a Monoclonal Antibody Fab-1 Fragment with Fast Photochemical Oxidation of Proteins (FPOP) and Mass Spectrometry. Journal of the American Society For Mass Spectrometry
Liao J, Hwang SH, Li H, et al. (2015) Inhibition of mutant Kras(G12D) -initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. Cancer Letters
Wecksler AT, Kalo MS, Deperalta G. (2015) Mapping of Fab-1:VEGF Interface Using Carboxyl Group Footprinting Mass Spectrometry. Journal of the American Society For Mass Spectrometry
Kaur P, Tomechko SE, Kiselar J, et al. (2015) Characterizing monoclonal antibody structure by carboxyl group footprinting. Mabs. 7: 540-52
Wecksler AT, Hwang SH, Liu JY, et al. (2015) Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemotherapy and Pharmacology. 75: 161-71
Kaur P, Tomechko S, Kiselar J, et al. (2014) Characterizing monoclonal antibody structure by carbodiimide/GEE footprinting. Mabs. 6: 1486-99
Morisseau C, Wecksler AT, Deng C, et al. (2014) Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. Journal of Lipid Research. 55: 1131-1138
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