Lauren E. Brown, Ph.D.
Affiliations: | University of California, Santa Cruz, Santa Cruz, CA, United States |
Area:
Synthetic organic chemistry; heterocyclic chemistry, bio-organic chemistryGoogle:
"Lauren Brown"Mean distance: 9.63 | S | N | B | C | P |
Parents
Sign in to add mentor| Nicos A. Petasis | research assistant | 2001-2003 | USC | |
| Joseph P. Konopelski | grad student | 2009 | UC Santa Cruz | |
| (Synthetic studies toward welwistatin, psymberin and a protective pharmaceutical.) | ||||
| Scott E. Schaus | post-doc | 2009-2012 | Boston University | |
| John A. Porco | research scientist | 2012-2014 | Boston University | |
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Publications
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| Fallah S, Duncan D, Reichl KD, et al. (2024) A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen . Microbiology Spectrum. e0409523 |
| Millimaci AM, Trilles RV, McNeely JH, et al. (2023) Synthesis of Neocannabinoids Using Controlled Friedel-Crafts Reactions. The Journal of Organic Chemistry |
| Naineni SK, Cencic R, Robert F, et al. (2023) Exploring the Targeting Spectrum of Rocaglates Among eIF4A Homologs. Rna (New York, N.Y.) |
| Kavouris JA, McCall LI, Giardini MA, et al. (2023) Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of infection. Frontiers in Tropical Diseases. 3 |
| Shaashua L, Ben-Shmuel A, Pevsner-Fischer M, et al. (2022) BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling. Nature Communications. 13: 6513 |
| Brown LE, Seitz S, Kondas AV, et al. (2022) Identification of Small Molecules with Improved Potency against Orthopoxviruses from Vaccinia to Smallpox. Antimicrobial Agents and Chemotherapy. e0084122 |
| Lehman SL, Wechsler T, Schwartz K, et al. (2022) Inhibition of the translation initiation factor eIF4A enhances tumor cell radiosensitivity. Molecular Cancer Therapeutics |
| Praditya DF, Klöhn M, Brüggemann Y, et al. (2022) Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication. Antiviral Research. 105359 |
| Xu W, Brown LE, Porco JA. (2021) Divergent, C-C Bond Forming Macrocyclizations Using Modular Sulfonylhydrazone and Derived Substrates. The Journal of Organic Chemistry |
| Chatterjee S, Yabaji SM, Rukhlenko OS, et al. (2021) Channeling macrophage polarization by rocaglates increases macrophage resistance to . Iscience. 24: 102845 |