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Ann R. Spevacek, Ph.D.

Affiliations: 
Chemistry University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
biophysical methods to study neurological proteins, their cofactors and how misregulation contributes to disease
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"Ann Spevacek"
Mean distance: 11.71
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Glenn L. Millhauser grad student 2012 UC Santa Cruz
 (The influence of metal ions on the tertiary structure of the prion protein and inherited prion disease.)

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Publications

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Stellato F, Minicozzi V, Millhauser GL, et al. (2014) Copper-zinc cross-modulation in prion protein binding. European Biophysics Journal : Ebj. 43: 631-42
Stellato F, Minicozzi V, Millhauser GL, et al. (2014) Copper-zinc cross-modulation in prion protein binding European Biophysics Journal. 43: 631-642
Spevacek AR, Evans EG, Miller JL, et al. (2013) Zinc drives a tertiary fold in the prion protein with familial disease mutation sites at the interface. Structure (London, England : 1993). 21: 236-46
Stellato F, Spevacek A, Proux O, et al. (2011) Zinc modulates copper coordination mode in prion protein octa-repeat subdomains European Biophysics Journal. 40: 1259-1270
Spevacek AR, Howard A, Millhauser GL. (2010) The Influence of Zn2+ on the Global Structure of the Prion Protein Biophysical Journal. 98: 175a
Walter ED, Stevens DJ, Spevacek AR, et al. (2009) Copper binding extrinsic to the octarepeat region in the prion protein. Current Protein & Peptide Science. 10: 529-35
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