Christine M. Dunham, Ph.D.

Affiliations: 
Emory University, Atlanta, GA 
Area:
RNA structure, catalysis and the origin of life
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Parents

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William Gregory Scott grad student 2003 UC Santa Cruz
 (Structural and mechanistic studies of an RNA enzyme.)
Venkatraman Ramakrishnan post-doc 2004-2008 MRC-LMB

Children

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Crystal Fagan grad student Emory
Eric D. Hoffer grad student Emory
Ha An Nguyen grad student Emory
Ian J. Pavelich grad student Emory
Marc Schureck grad student Emory
Pooja Srinivas grad student Emory
Jack A. Dunkle post-doc Emory
Samuel Hong post-doc Emory
Tatsuya Maehigashi post-doc Emory (Neurotree)
Ajchareeya Ruangprasert post-doc Emory
S. Sunita post-doc Emory
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Publications

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Hoffer E, Hong S, Sunita S, et al. (2020) Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife. 9
Nguyen HA, Sunita S, Dunham CM. (2020) Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proceedings of the National Academy of Sciences of the United States of America
Nosrati M, Dey D, Mehrani A, et al. (2019) Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition. The Journal of Biological Chemistry
Pavelich IJ, Maehigashi T, Hoffer ED, et al. (2019) Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Research
Schureck MA, Meisner J, Hoffer ED, et al. (2019) Structural basis of transcriptional regulation by the HigA antitoxin. Molecular Microbiology
Nguyen HA, Hoffer ED, Dunham CM. (2019) Importance of tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing in tRNA for decoding. The Journal of Biological Chemistry
Hoffer ED, Maehigashi T, Fredrick K, et al. (2018) Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Nucleic Acids Research
Rivera S, Young PG, Hoffer ED, et al. (2018) Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors. Inorganic Chemistry
Hong S, Sunita S, Maehigashi T, et al. (2018) Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proceedings of the National Academy of Sciences of the United States of America
Zhang Y, Hong S, Ruangprasert A, et al. (2018) Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel. Structure (London, England : 1993)
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