Premal H. Patel, Ph.D.

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
mutations and human cancer
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"Premal Patel"
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Parents

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Lawrence A. Loeb grad student 2001 University of Washington
 (Evolution of DNA polymerase active site.)
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Publications

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Patel PH, Loeb LA. (2001) Getting a grip on how DNA polymerases function. Nature Structural Biology. 8: 656-9
Patel PH, Suzuki M, Adman E, et al. (2001) Prokaryotic DNA polymerase I: evolution, structure, and "base flipping" mechanism for nucleotide selection. Journal of Molecular Biology. 308: 823-37
Shinkai A, Patel PH, Loeb LA. (2001) The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable. The Journal of Biological Chemistry. 276: 18836-42
Patel PH, Kawate H, Adman E, et al. (2001) A single highly mutable catalytic site amino acid is critical for DNA polymerase fidelity. The Journal of Biological Chemistry. 276: 5044-51
Patel PH, Loeb LA. (2000) Multiple amino acid substitutions allow DNA polymerases to synthesize RNA. The Journal of Biological Chemistry. 275: 40266-72
Patel PH, Loeb LA. (2000) DNA polymerase active site is highly mutable: evolutionary consequences. Proceedings of the National Academy of Sciences of the United States of America. 97: 5095-100
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